魏力｜海南师范大学｜学者主页

2026

珊瑚共生虫黄藻对高浓度CO2的响应机制

冯梦，冯渴芯，魏力

《海南师范大学学报(自然科学版)》

2026

Integrated proteomics and glycoproteomics reveal metabolic reprogramming in Nannochloropsis oceanica under CO₂ limitation

Yikai Wu, Meng Feng, Xiangchen Gao, Yunfei Gao, Zhengru Xu, Hang Su, Li Wei

BMC Plant Biology

DOI

2025

SCAP Interacts with Trim27 to Promote Vascular Neointimal Hyperplasia by Regulating the Stability and Ubiquitination of IκBα

Yingcheng Yao, Xing Wang, Chengcheng Xuan, Da Li, Wen-Qin Huang, Li Wei, Xiong Z. Ruan, Dan-Yang Li, Ya-Xi Chen

Aging and Disease

DOI

2025

Selenoprotein K-dependent MyD88 palmitoylation promotes hepatic metaflammation in high-fat diet fed mice.

Mengyue You, Yun Zhang, Mei-Ling Gao, Wei Zhao, Li Wei, Xiong Z Ruan, Ya-Xi Chen

Free Radical Biology & Medicine

DOI

2025

Advances in epigenetics and epigenome editing in microalgae

Meng Feng, Jiaqi Zhang, Li Wei

Food Bioscience

DOI

2025

Epitranscriptomic reprogramming in response to low CO 2 stress and m 6 A engineering to enhance biomass production in Nannochloropsis oceanica

Han Zhu, Yikai Wu, Meng Feng, Lingyu Ouyang, Hang Su, Li Wei

The Plant Journal

DOI

2025

Transcriptomic Survey of How Acetate Addition Affected the Growth in Nannochloropsis oceanica (Suda & Miyashita) R. E. Lee

Yikai Wu, Han Zhu, Hang Su, Li Wei

Life

DOI

2025

Global Profiling of Lysine Succinylation Reveals the Regulation of Carbon Fixation and Oil Production in Nannochloropsis oceanica

Jiecan Yu, Hang Su, Li Wei

Journal of Agricultural and Food Chemistry

DOI

2024

Systemic loss of CD36 aggravates NAFLD-related HCC through MEK1/2-ERK1/2 signaling pathway.

Enze Zheng, Qianqian Chen, Anhua Xiao, Xiaoqing Luo, Qian-Nan Lu, Chuan Tian, Huan Liu, Jinqing Zhao, Li Wei, Ping Yang, Ya-Xi Chen

Biochemical and Biophysical Research Communications - BBRC

DOI

2024

The fatty acid receptor CD36 promotes macrophage infiltration via p110γ signaling to stimulate metastasis

H. Qin, Anhua Xiao, Qian-Nan Lu, Yiyu Li, Xiaoqing Luo, Enze Zheng, Chuan Tian, Huan Liu, Xiaoya Zheng Resource, Li Wei, Xiong Z Ruan, Ping Yang, Ya-Xi Chen

Journal of Advanced Research

DOI

2024

Guanidine‐Derived Polymeric Nanoinhibitors Target the Lysosomal V‐ATPase and Activate AMPK Pathway to Ameliorate Liver Lipid Accumulation

Yunfei Zhao, Ke Hu, Fan Wang, Lulu Zhao, Yu Su, Jun Chen, Gang Zou, Liming Yang, Li Wei, Mengjiao Deng, Yunyu He, Ping Wang, Xiong Z Ruan, Ya-Xi Chen, Chao Yu

Advancement of science

DOI

2024

Global Profiling of Protein Phosphorylation, Acetylation, and β-Hydroxybutyrylation in Nannochloropsis oceanica

Lingyu Ouyang, Wuxin You, Ansgar Poetsch, Li Wei

Journal of Agricultural and Food Chemistry

DOI

2024

Transcriptomic Analysis Reveals the Effect of Urea on Metabolism of Nannochloropsis oceanica

Han Zhu, Zhenli Ye, Zhengru Xu, Li Wei

Life

DOI

2024

Integration of Epigenome and Lactylome Reveals the Regulation of Lipid Production in Nannochloropsis oceanica

Lingyu Ouyang, Jiao Wang, Han Zhu, Yikai Wu, Li Wei

Journal of Agricultural and Food Chemistry

DOI

2023

CD36 regulates diurnal glucose metabolism and hepatic clock to maintain glucose homeostasis in mice

Meng-Yue Chen, Yang Zhang, Shu-Yan Zeng, Dan-Yang Li, Mengyue You, Mingyang Zhang, Zhenyu Wang, Li Wei, Ya-Xi Chen, X. Ruan

iScience

DOI

2023

CES1‐Triggered Liver‐Specific Cargo Release of CRISPR/Cas9 Elements by Cationic Triadic Copolymeric Nanoparticles Targeting Gene Editing of PCSK9 for Hyperlipidemia Amelioration

Yunfei Zhao, Yun Li, Fan Wang, Xuelan Gan, Tian Zheng, Mengyue Chen, Li Wei, Jun Chen, Chao Yu

Advancement of science

DOI

2023

Hepatocyte CD36 modulates UBQLN1-mediated proteasomal degradation of autophagic SNARE proteins contributing to septic liver injury

Yanping Li, Jingyuan Xu, Weiting Chen, Xingxing Wang, Zhi-Bo Zhao, Yuqi Li, Linkun Zhang, Junkui Jiao, Qin Yang, Qiuying Ding, Ping Yang, Li Wei, Yao Chen, Ya-Xi Chen, X. Ruan, Lei Zhao

Autophagy

DOI

2023

SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice

G. Zheng, Yu Su, Li Wei, Yingcheng Yao, Yi-Zhe Wang, Xiao-lin Luo, Xing Wang, X. Ruan, Dan-Yang Li, Ya-Xi Chen

Cell Death and Disease

DOI

2023

Remodeling of the 3D chromatin architecture in the marine microalga Nannochloropsis oceanica during lipid accumulation

Tongtong Yan, Kexin Wang, Kexin Feng, Xiangchen Gao, Yinghong Jin, Hongping Wu, Wenfei Zhang, Li Wei

Biotechnology for Biofuels and Bioproducts

DOI

2023

Novel Insight of Nitrogen Deprivation Affected Lipid Accumulation by Genome-Wide Lactylation in Nannochloropsis oceanica

Jiao Wang, Lingyu Ouyang, Li Wei

Journal of Agricultural and Food Chemistry

DOI

2022

Inhibition of Fatty Acid Translocase (FAT/CD36) Palmitoylation Enhances Hepatic Fatty Acid β-Oxidation by Increasing Its Localization to Mitochondria and Interaction with Long-Chain Acyl-CoA Synthetase 1

Shu-Yan Zeng, Fan Wu, Mengyue Chen, Yun Li, Mengyue You, Y. Zhang, Ping Yang, Li Wei, X. Ruan, Lei Zhao, Ya-Xi Chen

Antioxidants and Redox Signaling

DOI

2022

Selenoprotein K contributes to CD36 subcellular trafficking in hepatocytes by accelerating nascent COPII vesicle formation and aggravates hepatic steatosis

Mengyue You, Fan Wu, Meilin Gao, Mengyue Chen, Shu-Yan Zeng, Yang Zhang, Wei Zhao, Dan-Yang Li, Li Wei, X. Ruan, Ya-Xi Chen

Redox Biology

DOI

2022

Cholesterol sensor SCAP contributes to sorafenib resistance by regulating autophagy in hepatocellular carcinoma

Dan-Yang Li, Yingcheng Yao, Y. Rao, Xinyu Huang, Li Wei, Zhi-Mei You, G. Zheng, Xiaoli S Hou, Yu Su, Z. Varghese, J. Moorhead, Ya-Xi Chen, X. Ruan

Journal of experimental & clinical cancer research : CR

DOI

2022

CD36-mediated metabolic crosstalk between tumor cells and macrophages affects liver metastasis

Ping Yang, H. Qin, Yi-Yu Li, Anhua Xiao, Enze Zheng, H. Zeng, Chunxiao Su, Xiaoqing Luo, Qian-Nan Lu, Meng Liao, Lei Zhao, Li Wei, Z. Varghese, J. Moorhead, Ya-Xi Chen, X. Ruan

Nature Communications

DOI

2022

Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING–NF-κB Signaling Pathway

Xinyu Huang, Yingcheng Yao, Xiaoli S Hou, Li Wei, Y. Rao, Yu Su, G. Zheng, X. Ruan, Dan-Yang Li, Ya-Xi Chen

Cellular and Molecular Gastroenterology and Hepatology

DOI

2022

Identification and expression analysis of genome-wide long noncoding RNA responsive CO2 fluctuated environment in marine microalga Nannochloropsis oceanica

Li Wei, Bingqing Liu, Danmei Liu, Zhengru Xu, Ruiping Wang, Wenfei Zhang

Marine Pollution Bulletin

DOI

2021

Association of APOE E2 and low-density lipoprotein with depressive symptoms in Chinese senile schizophrenia inpatients: A cross-sectional study

Wei Li

Schizophrenia Research-Cognition，Vol. 23

DOI

2021

The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis

Xiaoqing Luo, Enze Zheng, Li Wei, H. Zeng, H. Qin, Xiaoyu Zhang, Meng Liao, Lin Chen, Lei Zhao, X. Ruan, Ping Yang, Ya-Xi Chen

Cell Death and Disease

DOI

2021

Sterol-resistant SCAP Overexpression in Vascular Smooth Muscle Cells Accelerates Atherosclerosis by Increasing Local Vascular Inflammation through Activation of the NLRP3 Inflammasome in Mice

Dan-Yang Li, Mihua Liu, Zhe Li, G. Zheng, A-mei Chen, Lei Zhao, Ping Yang, Li Wei, Ya-Xi Chen, X. Ruan

Aging and Disease

DOI

2021

CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing

H. Zeng, Hong Qin, Meng Liao, Enze Zheng, Xiaoqing Luo, Anhua Xiao, Yi-Yu Li, Lin Chen, Li Wei, Lei Zhao, X. Ruan, Ping Yang, Ya-Xi Chen

Molecular Metabolism

DOI

2021

Transcriptomic survey reveals multiple adaptation mechanisms in response to nitrogen deprivation in marine Porphyridium cruentum

Li Wei, Wuxin You, Zhengru Xu, Wenfei Zhang

PLoS ONE

DOI

2021

Characterization of a novel Bacillus thuringiensis toxin active against Aedes aegypti larvae

Jiangyu Wu, Li Wei, Jiali He, Kang Fu, Xinxin Li, Jia Luyu, Ruiping Wang, Wenfei Zhang

Acta Tropica

DOI

2021

A CRISPR/dCas9-based transcription activated system developed in marine microalga Nannochloropsis oceanica

Li Wei, Zhouyi Jiang, Bingqing Liu

Aquaculture

DOI

2020

SCAP knockout in SM22α-Cre mice induces defective angiogenesis in the placental labyrinth.

Zhe Li, Dan-Yang Li, Y. Rao, Li Wei, Mihua Liu, G. Zheng, Yingcheng Yao, Xiaoli S Hou, Ya-Xi Chen, X. Ruan

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI

2020

Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function

Xiaoxiao Luo, Yanping Li, Ping Yang, Yao Chen, Li Wei, Ting Yu, Jun Xia, X. Ruan, Lei Zhao, Ya-Xi Chen

EBioMedicine

DOI

2020

Loss of CD36 impairs hepatic insulin signaling by enhancing the interaction of PTP1B with IR

Ping Yang, H. Zeng, Wei Tan, Xiaoqing Luo, Enze Zheng, Lei Zhao, Li Wei, Xiong Z. Ruan, Yao Chen, Ya-Xi Chen

The FASEB Journal

DOI

2019

High olive oil diets enhance cervical tumour growth in mice: transcriptome analysis for potential candidate genes and pathways

Xiaoyu Zhang, Ping Yang, Xuan Luo, Chunxiao Su, Yao Chen, Lei Zhao, Li Wei, H. Zeng, Z. Varghese, J. Moorhead, X. Ruan, Ya-Xi Chen

Lipids in Health and Disease

DOI

2019

CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway[S]

Yun Li, Ping Yang, Lei Zhao, Yao Chen, Xiaoyu Zhang, Shu-Yan Zeng, Li Wei, Z. Varghese, J. Moorhead, Ya-Xi Chen, X. Ruan

Journal of Lipid Research

DOI

2018

Long-chain fatty acid activates hepatocytes through CD36 mediated oxidative stress

Jun Liu, Ping Yang, Guo-qing Zuo, Song-Yuan He, Wei Tan, Xiaoyu Zhang, Chunxiao Su, Lei Zhao, Li Wei, Yao Chen, Xiong-Zhong Ruan, Ya-Xi Chen

Lipids in Health and Disease

DOI

2018

SCAP knockdown in vascular smooth muscle cells alleviates atherosclerosis plaque formation via up‐regulating autophagy in ApoE−/− mice

Dan-Yang Li, A-mei Chen, T. Lan, Yang Zou, Lei Zhao, Ping Yang, Haiyang Qu, Li Wei, Z. Varghese, J. Moorhead, Ya-Xi Chen, X. Ruan

The FASEB Journal

DOI

2018

Dietary oleic acid-induced CD36 promotes cervical cancer cell growth and metastasis via up-regulation Src/ERK pathway.

Ping Yang, Chunxiao Su, Xuan Luo, H. Zeng, Lei Zhao, Li Wei, Xiaoyu Zhang, Z. Varghese, J. Moorhead, Ya-Xi Chen, X. Ruan

Cancer Letters

DOI

2018

CD36对炎症因子TNF-α和IL-6诱发HepG2细胞胞内脂质聚集的影响

Li Wei, Li Wei, Jun Wu, Jun Wu, Lei Zhao, Lei Zhao, Ya-xi Chen, Ya-xi Chen, Ping Yang, Ping Yang

DOI

2017

Suppression of CD36 attenuates adipogenesis with a reduction of P2X7 expression in 3T3-L1 cells.

Huanqing Gao, Dan-Yang Li, Ping Yang, Lei Zhao, Li Wei, Ya-Xi Chen, X. Ruan

Biochemical and Biophysical Research Communications - BBRC

DOI

2017

Inflammatory stress promotes the development of obesity-related chronic kidney disease via CD36 in mice[S]

Ping Yang, Yanan Xiao, Xuan Luo, Yunfei Zhao, Lei Zhao, Yan Wang, Tingting Wu, Li Wei, Ya-Xi Chen

Journal of Lipid Research

DOI

精选作品

期刊论文

珊瑚共生虫黄藻对高浓度CO2的响应机制

Integrated proteomics and glycoproteomics reveal metabolic reprogramming in Nannochloropsis oceanica under CO₂ limitation

SCAP Interacts with Trim27 to Promote Vascular Neointimal Hyperplasia by Regulating the Stability and Ubiquitination of IκBα

Selenoprotein K-dependent MyD88 palmitoylation promotes hepatic metaflammation in high-fat diet fed mice.

Advances in epigenetics and epigenome editing in microalgae

Epitranscriptomic reprogramming in response to low CO 2 stress and m 6 A engineering to enhance biomass production in Nannochloropsis oceanica

Transcriptomic Survey of How Acetate Addition Affected the Growth in Nannochloropsis oceanica (Suda & Miyashita) R. E. Lee

Global Profiling of Lysine Succinylation Reveals the Regulation of Carbon Fixation and Oil Production in Nannochloropsis oceanica

Systemic loss of CD36 aggravates NAFLD-related HCC through MEK1/2-ERK1/2 signaling pathway.

The fatty acid receptor CD36 promotes macrophage infiltration via p110γ signaling to stimulate metastasis

Guanidine‐Derived Polymeric Nanoinhibitors Target the Lysosomal V‐ATPase and Activate AMPK Pathway to Ameliorate Liver Lipid Accumulation

Global Profiling of Protein Phosphorylation, Acetylation, and β-Hydroxybutyrylation in Nannochloropsis oceanica

Transcriptomic Analysis Reveals the Effect of Urea on Metabolism of Nannochloropsis oceanica

Integration of Epigenome and Lactylome Reveals the Regulation of Lipid Production in Nannochloropsis oceanica

CD36 regulates diurnal glucose metabolism and hepatic clock to maintain glucose homeostasis in mice

CES1‐Triggered Liver‐Specific Cargo Release of CRISPR/Cas9 Elements by Cationic Triadic Copolymeric Nanoparticles Targeting Gene Editing of PCSK9 for Hyperlipidemia Amelioration

Hepatocyte CD36 modulates UBQLN1-mediated proteasomal degradation of autophagic SNARE proteins contributing to septic liver injury

SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice

Remodeling of the 3D chromatin architecture in the marine microalga Nannochloropsis oceanica during lipid accumulation

Novel Insight of Nitrogen Deprivation Affected Lipid Accumulation by Genome-Wide Lactylation in Nannochloropsis oceanica

Inhibition of Fatty Acid Translocase (FAT/CD36) Palmitoylation Enhances Hepatic Fatty Acid β-Oxidation by Increasing Its Localization to Mitochondria and Interaction with Long-Chain Acyl-CoA Synthetase 1

Selenoprotein K contributes to CD36 subcellular trafficking in hepatocytes by accelerating nascent COPII vesicle formation and aggravates hepatic steatosis

Cholesterol sensor SCAP contributes to sorafenib resistance by regulating autophagy in hepatocellular carcinoma

CD36-mediated metabolic crosstalk between tumor cells and macrophages affects liver metastasis

Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING–NF-κB Signaling Pathway

Identification and expression analysis of genome-wide long noncoding RNA responsive CO2 fluctuated environment in marine microalga Nannochloropsis oceanica

Association of APOE E2 and low-density lipoprotein with depressive symptoms in Chinese senile schizophrenia inpatients: A cross-sectional study

The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis

Sterol-resistant SCAP Overexpression in Vascular Smooth Muscle Cells Accelerates Atherosclerosis by Increasing Local Vascular Inflammation through Activation of the NLRP3 Inflammasome in Mice

CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing

Transcriptomic survey reveals multiple adaptation mechanisms in response to nitrogen deprivation in marine Porphyridium cruentum

Characterization of a novel Bacillus thuringiensis toxin active against Aedes aegypti larvae

A CRISPR/dCas9-based transcription activated system developed in marine microalga Nannochloropsis oceanica

SCAP knockout in SM22α-Cre mice induces defective angiogenesis in the placental labyrinth.

Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function

Loss of CD36 impairs hepatic insulin signaling by enhancing the interaction of PTP1B with IR

High olive oil diets enhance cervical tumour growth in mice: transcriptome analysis for potential candidate genes and pathways

CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway[S]

Long-chain fatty acid activates hepatocytes through CD36 mediated oxidative stress

SCAP knockdown in vascular smooth muscle cells alleviates atherosclerosis plaque formation via up‐regulating autophagy in ApoE−/− mice

Dietary oleic acid-induced CD36 promotes cervical cancer cell growth and metastasis via up-regulation Src/ERK pathway.

CD36对炎症因子TNF-α和IL-6诱发HepG2细胞胞内脂质聚集的影响

Suppression of CD36 attenuates adipogenesis with a reduction of P2X7 expression in 3T3-L1 cells.

Inflammatory stress promotes the development of obesity-related chronic kidney disease via CD36 in mice[S]