堵国成，江南大学生物工程学院教授、博士生导师，长期从事发酵工程和微生物代谢工程领域的教学与科研工作。研究方向包括轻工业手工业、生物学、一般化学工业。担任Microb Cell Fact副主编、Journal of the Science of Food and Agriculture编委、Bioresource Technology编委。
Fengling Yang, Ruirui Xu, Hao Huang, Jie Lu, Jiamin Feng, Xiaoyuan Sun, Jiang-Hua Li, Guo-Cheng Du, Zhen Kang (2026). Controllable Polysaccharide Depolymerization by Heparinases for Efficient Low Molecular Weight Heparin Production. Carbohydrate Polymer Technologies and Applications.DOI
Ping Zhang, Weijiao Zhang, Haibo Xiong, Guo-Bin Yin, Guo-Cheng Du, Jian Chen, Jiang-Hua Li, Ruirui Xu, Zhen Kang (2026). Multidimensionally engineered Escherichia coli for efficient gadusol biosynthesis with high-throughput quantitative analysis. Trends in Biotechnology.DOI
Xintong Xi, Ruirui Xu, Daoan Wang, Guo-Bin Yin, Xin-Jing Wang, Hai-Qin Chen, Guo-Cheng Du, Jian Chen, Zhen Kang (2026). Design and Engineering of an Artificial Bifunctional N‐Deacetylase/N‐Sulfotransferase for the Biosynthesis of N‐Sulfated Heparosan. Advancement of science.DOI
Xin-Wei Gao, Hao Huang, Li-Tao Hu, Weiquan Ding, Zhiliang Hou, Ruirui Xu, Guo-Cheng Du, Zhen Kang (2026). High-molecular weight hyaluronic acid protects against colitis by remodeling microbiota and restoring barrier function. Carbohydrate Polymers.DOI
Jie Lu, Xiaoyuan Sun, Hanzhi Weng, Weiquan Ding, Fengling Yang, Guo-Cheng Du, Ruirui Xu, Zhen Kang (2026). Scalable ergothioneine production via integrating chemical methylation and rhodanese-catalyzed C S bond formation. Chemical Engineering Journal.DOI
Luyao Zhang, Guo-Bin Yin, Sen-Yu Pan, Xi-Nai Zheng, Siyan Zhou, Guo-Cheng Du, Jiang-Hua Li, Jian Chen, Ruirui Xu, Zhen Kang (2026). Engineering a heme-dependent tryptophan hydroxylase pathway in E. coli for enhanced melatonin production. Synthetic and Systems Biotechnology.DOI
Xin-Jing Wang, Ya-Xin Yu, Ping Dong, Daoan Wang, Ruirui Xu, Guo-Cheng Du, Xintong Xi, Zhen Kang (2026). Expression Optimization and Semirational Engineering of Ga6OST1 for Improved Catalytic Performance in Heparin Biosynthesis. ACS Synthetic Biology.DOI
顾升波，Na Wang，Yadong Tu，Jialu Li，Huiyue Li，Jianhua Bao，Yaokang Wu，Xueqin Lv，Long Liu，Guocheng Du，Jian Chen，Yanfeng Liu (2026). Replicon engineering-driven modular synthetic biology toolkit for efficiently iterative genome editing in Fusarium venenatum. Metabolic Engineering.DOI
Xiaohui Wu, Shijun Luo, Yaru Chen, Guocheng Du, Jian Chen, Xiao Liu (2026). High-Level Mycoprotein Production through Metabolic Regulation of Concanavalin A-Like Lectin/Glucanase Domain-Containing Protein in Fusarium venenatum. Journal of Agricultural and Food Chemistry.DOI
Baodong Hu, Cuiping Pang, Ding Luo, Yongchao Wang, Chixiang Sun, Jingwen Zhou, Jian Chen, Guocheng Du, Fang Zhong, Jiahai Zhou, Binju Wang, Xinrui Zhao (2026). Corrigendum to “Improved catalytic efficiency of P450 OleP for converting lithocholic acid into murideoxycholic and ursodeoxycholic acids through semi-rational and rational design” [Synth Syst Biotechnol 15 (2027) 94-104]. Synthetic and Systems Biotechnology.DOI
Chihe Sun, Ling Zhang, Xianzhong Chen, Long Liu, Guocheng Du (2026). [Construction and practice of a talent training model for synthetic biology]. PubMed.DOI
Yangyang Li, Ke Jin, Jiangong Lu, Haidong Huang, XIANHAO XU, Guocheng Du, Zhendong Li, Jian Chen, Long Liu, Xueqin Lv (2026). Mechanism‐Guided Synergistic Engineering of Substrate Access and Catalytic Microenvironment in Oxidosqualene Cyclase for Enhanced Amyrin Biosynthesis. Biotechnology and Bioengineering.DOI
Yanan Sun, Yuhan Zhang, Yulong Xiang, Guosen Cheng, Jianghua Li, Jian Chen, Guocheng Du, Yang Wang (2026). Characterization and engineering of carbohydrate-binding modules from novel Paenibacillus polysaccharide lyases for in situ glycosaminoglycans visualization. Chemical Engineering Journal.DOI
Xuan Zhou, Jiaheng Hou, Zikai Wang, Zhendong Li, Yang Li, Xitong Li, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Dacheng Ma, Jian Tang, Jian Chen, Xueqin Lv, Long Liu (2026). De novo L-(+)-tartaric acid biosynthesis in multi-modular engineered yeasts. Nature Communications.DOI
Haidong Huang, Yangyang Li, Jinsong Song, Yuhan Zhao, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Zhendong Li, Xueqin Lv, Xianhao Xu, Long Liu (2026). Computationally Guided Engineering of Multi-Enzyme Cascades Enables Efficient Trehalose Biosynthesis. Journal of Agricultural and Food Chemistry.DOI
Anqi Chen, Qingyun Xu, Jiaming Li, Yuehua Chen, Qiance Shen, Guocheng Du, Jianghua Li, J S Chen (2026). Time-resolved volatile profiles and molecular-species lipid remodeling during lipase treatment of anhydrous milk fat. Food Research International.DOI
Yang Liu, Caiyin Jin, Wentao Shen, Yaokang Wu, Xueqin Lv, J H Li, L T Liu, Guocheng Du, J X Chen, Yanfeng Liu (2026). Precursor supply and translational machinery engineering of Saccharomyces cerevisiae for improving cellular protein content and biomass-based microbial protein bioproduction. Bioresource Technology.DOI
Le Zeng, Tian Yang, Pengfei Sun, Guocheng Du, X D Liu, J S Chen, Yue Wang (2026). Modulating wettability of yeast protein particles by ball-milling to fabricate capillary oleogels with tunable rheology. Food Chemistry.DOI
Zhiqiang Liu, Binglin Li, Jieying Deng, Yanfeng Liu, J Li, Guocheng Du, J S Chen, Xueqin Lv, Xianhao Xu, Long Liu (2026). Plasmid- and Inducer-Free Biosynthesis of Difucosyllactose through Rational Fusion Enzyme Engineering and Systematic Pathway Optimization. ACS Synthetic Biology.DOI
Shijun Luo, Wu Xl, Guocheng Du, Jian Chen, Xiao Liu (2026). Sustainable bioconversion of food waste into high-yield and low-RNA Fusarium venenatum mycoprotein. Bioresource Technology.DOI
Baodong Hu, Cuiping Pang, Ding Luo, Yue Wang, Chixiang Sun, Jin Zhou, J S Chen, Guocheng Du, Fang Zhong, Jin Zhou, B Q Wang, Xinrui Zhao (2026). Improved catalytic efficiency of P450 OleP for converting lithocholic acid into murideoxycholic and ursodeoxycholic acids through semi-rational and rational design. Synthetic and Systems Biotechnology.DOI
Anqi Chen, Chenwei Pan, Chen Bo, Weiming Xiao, Guocheng Du, J Li, Hui Liu, J S Chen (2026). Coordinated metabolic and structural adaptation drives improved baking performance of a robust Saccharomyces cerevisiae strain in high-sugar dough. Food Research International.DOI
Qi Li, J Li, Guocheng Du, Zhaofeng Li, Guoqiang Zhang, Song Liu (2026). High-throughput screening to improve the yield of Monascus red pigment from Monascus purpureus. Systems Microbiology and Biomanufacturing.DOI
Yi Yang, Ping Lin, Guocheng Du, Jian Chen, Zheng Peng, J F Zhang (2026). Engineered Microbial Production of Sesquiterpenoids: Recent Advances and Prospects. ACS Synthetic Biology.DOI
Xiangdi Chen, Shuaili Chen, Jingwen Zhou, Guocheng Du, Guoqiang Zhang (2026). In situ continuous evolution of native transporter HGT1 unlocks xylose utilization in Kluyveromyces lactis. Synthetic and Systems Biotechnology.DOI
Pengfei Chen, Guocheng Du, Jian Chen, Fang Fang (2026). Construction of Synthetic Microbial Community with Core Microorganisms for Soy Sauce Fermentation. Foods.DOI
Kai Gu, Ping Lin, Guocheng Du, Jian Chen, J F Zhang, Zheng Peng (2026). Engineering Modification for the Efficient Synthesis of β‐ionone by Yarrowia lipolytica. Biotechnology Journal.DOI
Jiayi Luo, Baodong Hu, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2026). Efficient Secretory Expression of Soybean Peroxidase in Saccharomyces cerevisiae Through Systematic Engineering. Journal of Agricultural and Food Chemistry.DOI
Yulong Xiang, Huawei Li, Jianghua Li, Guocheng Du, Jian Chen, Yang Wang (2026). Uncovering N‐Glycosylation‐Mediated Allosteric Activation Coupled With Stability Design Enabling High‐Yield Human Enterokinase Production. Biotechnology and Bioengineering.DOI
Yuting Shi, Yanmei Li, Jiaheng Liu, Dongxu Chen, XIANHAO XU, Zhendong Li, Yanfeng Liu, Guocheng Du, Jianghua Li, Jian Chen, Xueqin Lv, L T Liu (2026). Combinatorial engineering of Saccharomyces cerevisiae for high level production of astaxanthin. Systems Microbiology and Biomanufacturing.DOI
Yanan Wang, Le Zeng, Tianxi Sun, Pengfei Sun, Hanyun Jiang, Guocheng Du, Jian Chen, Xiaojing Liu (2026). High-pressure modified yeast protein for stabilizing high internal phase emulsions with nonlinear rheological behavior and lubrication property. Innovative Food Science & Emerging Technologies.DOI
Qinan Shao, Yulong Xiang, Mingcong Xu, Jianghua Li, Guocheng Du, Jian Chen, Yang Wang (2026). Harnessing Pichia pastoris microbial cell factory construction and site-specific proteolysis for the production of native-form sweet-tasting protein brazzein. Food Bioscience.DOI
Jinming Xie, Lingjie Kong, Guocheng Du, Jian Chen, Zheng Peng, Juan Zhang (2026). Heterologous expression of Listeria monocytogenes-targeting bacteriocin in Bacillus subtilis. Food Bioscience.DOI
Dejun Wan, Baodong Hu, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2026). Efficient biosynthesis of serotonin and melatonin through combinatorial metabolic engineering in Escherichia coli. Food Bioscience.DOI
Xiaohui Wu, Mengru Wang, Xinwen Zhang, Zhitong Zhou, Yanan Wang, Jianghua Li, Guocheng Du, Jian Chen, Xiao Liu (2026). Toward the Next-Generation of Alternative Protein Production from Sustainability-Oriented Technological Revolution. Journal of Agricultural and Food Chemistry.DOI
Binglin Li, Zhiqiang Liu, Yanfeng Liu, Yanfeng Liu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, XIANHAO XU, Long Liu (2026). Engineering plasmid-free, antibiotic-free, and inducer-free Escherichia coli strain for efficient 2′-fucosyllactose biosynthesis. Bioresource Technology.DOI
Yameng Tan, Penghui Yang, Wenxuan Qiu, Hongjian Xue, Guocheng Du, Jingwen Zhou, Song Liu (2026). Thermostability Enhancement of Streptomyces mobaraensis Transglutaminase by Folding Free Energy-Guided Helix-Corner Motif Engineering. Journal of Agricultural and Food Chemistry.DOI
Wen Zhang, Yang Li, Zhendong Li, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu, Long Liu, Yaokang Wu, Ziyang Huang, Yanfeng Liu (2026). Multiple pathway engineering combined with tolerance engineering promotes high-level acetoin biosynthesis in Bacillus subtilis. Food Bioscience.DOI
Yang Li, Zhendong Li, Yufeng Lin, Yaokang Wu, XIANHAO XU, Yan Zhang, Yexu Wu, Yanfeng Liu, Jianghua Li, Jianghua Li, Guocheng Du, Xueqin Lv, Jian Chen, Long Liu (2026). A metabolizable inducer–based carbon-source autoinduction (MICA) system enables low-cost, high-level protein expression and metabolic control in Bacillus subtilis. Metabolic Engineering.DOI
Fang Luan, Yong Li, XIANHAO XU, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu, Zhendong Li, Xueqin Lv (2026). Multi‐Level Engineering of Bacillus Subtilis for High‐Level Extracellular Production of Functional Expansins. Biotechnology Journal.DOI
Tianai Kong, Yongrong Sun, Guobin Yin, Guosen Cheng, Jianghua Li, Guocheng Du, Jie Chen, Yang Wang (2026). A lightweight toolkit of synthetic promoters and regulatory sRNAs for gene expression regulation in industrial Streptococcus. Systems Microbiology and Biomanufacturing.DOI
Mengrui Wang, Yaokang Wu, Xueqin Lv, Jianghua Li, Long Liu, Long Liu, Guocheng Du, Jian Chen, Yanfeng Liu (2026). Balancing dual-enzyme expression and synergistically engineering of 4-hydroxyphenylpyruvate dioxygenase for efficient 3-hydroxy-3-methylbutyrate biosynthesis by whole-cell catalysis. Food Bioscience.DOI
Yangyang Li, Guocheng Du, Jianzhong Chen, Xueqin Lv, Long Liu (2026). Computational dual-loop frameworks bridging single-enzyme design and cascade tunnel network engineering for next-generation biosynthetic systems. Biotechnology Advances.DOI
Lingtong Liao, Xiuru Shen, Jianghua Li, Guocheng Du, Jian Chen, Guoqiang Zhang (2026). A dual strategy of metabolic engineering and multisite integration for enhanced lactase production in Kluyveromyces lactis. Chemical Engineering Journal.DOI
Yinghan Zhao, Tianxi Sun, Yanan Wang, Guocheng Du, Jian Chen, Jianghua Li, Xiao Liu, Xinwen Zhang (2026). Yeast protein-based high-moisture extrudates mimicking chicken breast in structural and digestive properties. Food Chemistry.DOI
Hongjian Xue, Jingwen Zhou, Guocheng Du, Song Liu (2026). Heterologous expression of phospholipase A1 in Streptomyces mobaraensis and its application in crude oil degumming. Process Biochemistry.DOI
Zijun Wang, Yaokang Wu, Xueqin Lv, Jianghua Li, Long Liu, Guocheng Du, Jian Chen, Yanfeng Liu (2026). Advances in the biosynthesis of milk proteins fueled by synthetic biology. Agricultural Products Processing and Storage.DOI
Minxia Song, Jiayi Liu, XIANHAO XU, Shixiu Cui, Yaokang Wu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2026). Multidimensional Engineering of Saccharomyces cerevisiae for Efficient Production of Retinol. Biotechnology Journal.DOI
Yangyang Li, Chenyang Zhang, Haidong Huang, XIANHAO XU, Yanfeng Liu, Guocheng Du, Jian Chen, Zhendong Li, Xueqin Lv, Long Liu (2026). Engineering the substrate tunnel of diacylglycerol acyltransferase ScDGA1 enhances triacylglycerol biosynthesis in Saccharomyces cerevisiae. International Journal of Biological Macromolecules.DOI
Yanting Cao, Yaokang Wu, Xueqin Lv, J. F. Li, Long Liu, Guocheng Du, J. Chen, Yanfeng Liu (2026). Development of central metabolite-responsive genetic circuits for auto-dynamic and multi-layered regulation of cell metabolism in Bacillus subtilis. Chemical Engineering Journal.DOI
XIANHAO XU, Keyi Zou, Weihao Qian, Xueqin Lv, Shixiu Cui, Yangyang Li, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Long Liu (2026). Engineering Programmable Tryptophan-Responsive Biosensors Based on RNA-Binding Attenuation Protein for Strain Optimization. ACS Synthetic Biology.DOI
Xin Guan, L. C. Wang, Wanqiang Sun, Yiwei Feng, Dandan Wang, Haohao Tang, Zhenwu Ma, Guocheng Du, Jian Chen, Jingwen Zhou (2026). Creating Cell‐Based Hybrid Noodles for Sustainable and Nutrient‐Balanced Diets via a Serum‐Free and Animal‐Free 3D Co‐Differentiation System. Advanced Science.DOI
Cenyu Su, Zhendong Li, XIANHAO XU, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2026). Combinatorial Engineering of Escherichia coli for Enhancing Lipoic Acid Production. ACS Synthetic Biology.DOI
Lingtong Liao, Laichuang Han, Yanfang Sun, Xuexian Du, Yuqi Wu, Jiaoyan Luo, Jianghua Li, Guocheng Du, Guoqiang Zhang (2026). Engineering β-Galactosidase with Enhanced Catalytic and Transglycosylation Activity for GOS Production. Journal of Agricultural and Food Chemistry.DOI
Bo Zeng, Shuiping Ouyang, Zhaoxiang Wang, Cui Shixiu, Guocheng Du, Song Liu (2026). Ancestral bacterial laccase enables efficient biodetoxification of inhibitory wheat straw hydrolysate for sustainable microbial protein production. Green Chemistry.DOI
Xiaofei Hu, Jiacai Ye, Jingwen Zhou, Du Guocheng, Song Liu (2026). Combinatorial optimization of ribosomal binding site, promoter and genomic locus for high-yield production of a thermostable transglutaminase in Streptomyces mobaraensis. Enzyme and Microbial Technology.DOI
Li-Tao Hu, Sen Xiao, Jieyu Sun, Fa-Yin Wang, Guo-Bin Yin, Wen-Jie Xu, Jian-Hua Cheng, Guo-Cheng Du, Jian Chen, Zhen Kang (2025). Regulating cellular metabolism and morphology to achieve high-yield synthesis of hyaluronan with controllable molecular weights. Nature Communications.DOI
Guo-Bin Yin, Luyao Zhang, Diwen Zhou, Siyan Zhou, Ruirui Xu, Guo-Cheng Du, Jian Chen, Zhen Kang (2025). Design of orthogonal and portable RNA devices for post-transcriptional regulation by reverse engineering type I toxin-antitoxin systems. Nucleic Acids Research.DOI
Wuxia Chen, Daoan Wang, Xintong Xi, Linpei Zhang, Guo-Cheng Du, Ruirui Xu, Zhen Kang (2025). Efficient Expression of an Engineered Heparan Sulfate 2-O-Sulfotransferase with Improved Catalytic Properties. Journal of Agricultural and Food Chemistry.DOI
Yangyang Li, Haidong Huang, XIANHAO XU, Yanfeng Liu, Yanfeng Liu, Guocheng Du, Jian Chen, Zhendong Li, Xueqin Lv, Long Liu (2025). Engineering microbial cell factories for milk-derived bioactive proteins: Structural-functional profiling, chassis selection, and full-pipeline expression control. Trends in Food Science & Technology.DOI
Shuya Zhang, Jianghua Li, Jian Chen, Guocheng Du, Guochang Sun, Zhifang Yu, Qingzhong Mao, Qizhong Wu, Ming Zhao, Lixia Yang, Mengsha Hu, Xinrui Zhao (2025). Characterization of bioactive compounds (GABA, glutathione, phenolic acids and isomaltooligosaccharides) and enhancement of GABA via mutagenesis during Shaoxing Huangjiu fermentation. International Journal of Food Science & Technology.DOI
Xin Geng, Maofang Teng, Qinghua Li, Juan Zhang, Jingwen Zhou, Jianghua Li, Guocheng Du, Guoqiang Zhang (2025). Intein-Mediated Proenzyme Activation for Protein-Glutaminase Production in Bacillus subtilis. Journal of Agricultural and Food Chemistry.DOI
Li Ying Sun, XIANHAO XU, Y. Wu, Yanfeng Liu, Tianmin Zhang, Jianghua Li, Guocheng Du, Long Liu, Xueqin Lv (2025). Transcription Factor ROX1 Controls Oxidative Stress Homeostasis in Saccharomyces cerevisiae at Low pH. Journal of Agricultural and Food Chemistry.DOI
Ruowei Hua, Yangyang Li, XIANHAO XU, Yanfeng Liu, Jianghua Li, Guocheng Du, Zhendong Li, J. Chen, Long Liu, Xueqin Lv (2025). Multiplexed Metabolic and Protein Engineering for D‐Limonene Overproduction in Saccharomyces cerevisiae. Biotechnology and Bioengineering.DOI
Siqi Liu, Jiangong Lu, Wenwen Yu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2025). Development of a CRISPR-Cpf1 and endogenous recombinase synergy platform for N-acetylglucosamine overproduction in Corynebacterium glutamicum S9114. Systems Microbiology and Biomanufacturing.DOI
Baoyuan Guo, Yangyang Li, Yujie Liu, Qingxin Zeng, Sun Li, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu, Xueqin Lv (2025). Reprogramming Carbon Flux to Eliminate Crabtree Effect-Associated Ethanol Production for High-Yield l -Lactic Acid Biosynthesis in Saccharomyces cerevisiae. Journal of Agricultural and Food Chemistry.DOI
Xiaohui Wu, Mengru Wang, Shijun Luo, Zhitong Zhou, Yanan Wang, Guocheng Du, Jian Chen, Xiao Liu (2025). Dual enhancement of mycoprotein nutrition and sustainability via CRISPR-mediated metabolic engineering of Fusarium venenatum. Trends in biotechnology.DOI
Fan Liu, Chunxiang Feng, Zirui Yin, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2025). Engineering strategies for microbial synthesis, customized modification, and application of hemoglobin. Biotechnology Advances.DOI
Shuangxin Han, Kecheng Sun, Xiaoping Hou, Xiujuan Wan, Jiahui Ding, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao, Hua Yin (2025). High-Throughput Screening of Industrial Brewing Yeast with Lower Synthetic Level of Acetaldehyde During Beer Production. Foods.DOI
Lei Peng, Wenwen Yu, Xianhao Xu, Yaokang Wu, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Long Liu, Xueqin Lv (2025). Directed evolution of α1,2-fucosyltransferase via a scalable high-throughput screening platform. International Journal of Biological Macromolecules.DOI
Zirui Yin, Fan Liu, Zhaoxuan Zhang, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2025). Application of synthetic biology in the cultured meat production. Trends in Food Science & Technology.DOI
Zixin Yao, Jianbin Weng, Mengxin Wang, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2025). Recent advances in microbial fermentation for the production of leghemoglobin. World Journal of Microbiology and Biotechnology.DOI
Xutao Lang, Wenwen Yu, Xuewen Zhu, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Xueqin Lv, Long Liu (2025). Multi-layered transcriptional and post-translational fine-tuning of metabolic pathways for overproduction of L-valine. Metabolic Engineering.DOI
Xiaohui Wu, Shijun Luo, Zhitong Zhou, Yanan Wang, Guocheng Du, Jian She Chen, Xiao Liu (2025). Tuning Fusarium venenatum mycelium structure through genetic modification for customized texture and digestibility of chicken breast analogues. Food Research International.DOI
Manxiang Zhu, Hongzhi Xia, Xianhao Xu, Yanfeng Liu, Guocheng Du, Xueqin Lv, Long Liu, Cui Shixiu, Jianghua Li, Y. Li (2025). A Novel De Novo Biosynthetic Pathway for Efficient Synthesis of 6′-Sialyllactose in Escherichia coli. ACS Synthetic Biology.DOI
Ping Lin, Guocheng Du, Jian Chen, Juan Zhang, Zheng Peng (2025). Engineered microbial production of carotenoids and their cleavage products: Recent advances and prospects. Biotechnology Advances.DOI
Xiaoxi Li, Wenwen Yu, Baoyuan Guo, Xutao Lang, Xiangnan Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2025). Metabolic engineering of Escherichia coli for biosynthesis of inosinic acid. Systems Microbiology and Biomanufacturing.DOI
Manxiang Zhu, Xianhao Xu, Xinyu Bi, Shixiu Cui, Yanfeng Liu, Guocheng Du, Xueqin Lv, Long Liu, Jianghua Li (2025). Development and application of synthetic biology tools for improved production of human breast milk components. Synthetic and Systems Biotechnology.DOI
Xiaohui Wu, Zhitong Zhou, Shijun Luo, Yanan Wang, Mingqian Yang, Yaru Chen, Guocheng Du, Jian Chen, Xiao Liu (2025). Cell wall engineering-guided strategy for high-efficiency biosynthesis of nutrient-fortified Fusarium venenatum mycoprotein. Bioresource Technology.DOI
Haohao Tang, Luyi Wang, Wanqiang Sun, Guocheng Du, Jingwen Zhou, Jian Chen, Xin Guan (2025). Production of cultured fat using peanut oil as a safe and efficient adipogenic inducer. Journal of Future Foods.DOI
Haibo Xiong, Xiaogang Yang, Weijiao Zhang, Litao Hu, Gege Liu, Guocheng Du, Jian Chen, Jianghua Li, Ruirui Xu, Zhen Kang (2025). Engineering Komagataella phaffii cell factories for the production of chondroitin sulfate A with high sulfation degree. Chemical Engineering Journal.DOI
Song Wang, Zhou Jingwen, Jianghua Li, Jian Chen, Guocheng Du, Zhengqiang Li, Sang Yup Lee, Xinrui Zhao (2025). Metabolic engineering of Bacillus subtilis for the production of active hemoglobins and myoglobins by improving heme supply. Proceedings of the National Academy of Sciences.DOI
Hongtao Chen, Yueheng Niu, Liuxia Zhang, Yunpeng Wang, Ao Luo, Zhihui Dai, Guocheng Du, Xinrui Zhao (2025). The optimized signal peptide and feeding strategy to enhance secretory expression of LegH in Komagataella phaffii. Process Biochemistry.DOI
Song Wang, Zirui Yin, Yue Fan, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Zhengqiang Li, Xinrui Zhao (2025). Engineering Corynebacterium glutamicum with Effective Heme Supply for the Synthesis of High-Activity Hemoglobins and Myoglobins. Journal of Agricultural and Food Chemistry.DOI
Xirui Hua, Wenwen Yu, Yangyang Li, Xiangnan Xu, Yaokang Wu, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu, Xueqin Lv (2025). A high-throughput screening platform for improving the rolling-circle amplification efficiency of Phi29 DNA polymerase under high-salt conditions. Systems Microbiology and Biomanufacturing.DOI
Yanting Cao, Yaokang Wu, Xueqin Lv, Jianghua Li, Long Liu, Guocheng Du, Jian Chen, Yanfeng Liu (2025). Reduced Genetic Heterogeneity for Stable Bioproduction by Harnessing the Bias and Mechanism of Mutation. Microbial Biotechnology.DOI
Yanfeng Liu, Guocheng Du, Jian Chen, Xueqin Lv, Long Liu (2025). Glycosyltransferases in human milk oligosaccharide synthesis: structural mechanisms and rational design. Current Opinion in Biotechnology.DOI
Tianzhi Qu, Guocheng Du, Jian Chen, Anqi Chen, Jianghua Li (2025). Development of Freeze–Thaw Tolerant Yeast Strains via a Hybrid Fusion Evolutionary Strategy. Journal of Agricultural and Food Chemistry.DOI
Yuhua Sheng, Yaokang Wu, Linpei Zhang, Xueqin Lv, Jianghua Li, Long Liu, Guocheng Du, Jian Chen, Yanfeng Liu (2025). Reconstitution of Methionine Cycle With ATP Regeneration for Whole‐Cell Catalysis of Creatine Production in Engineered Escherichia coli. Microbial Biotechnology.DOI
Xiaoyan Sun, Yunpeng Wang, Yijie Wang, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2025). Efficient Synthesis of High-Active Myoglobin and Hemoglobin by Reconstructing the Mitochondrial Heme Synthetic Pathway in Engineered Saccharomyces cerevisiae. Fermentation.DOI
Lingfeng Yi, Xinyue Li, Menglin She, Yaokang Wu, Jianghua Li, Guocheng Du, Long Liu, Li Wang, Yanfeng Liu (2025). High-throughput screening and inhibition mechanism analysis of Bacillus licheniformis BL-4 as an antagonistic strain for Lactobacillus panis. Systems Microbiology and Biomanufacturing.DOI
Bin Wang, Yaokang Wu, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Jian Chen, Yanfeng Liu (2025). T7 RNA polymerase-guided base editor for accelerated continuous evolution in Bacillus subtilis. Synthetic and Systems Biotechnology.DOI
Bin Qi, Jianing Zhang, Wenlong Ma, Yaokang Wu, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Yanfeng Liu (2025). Biosensor-Assisted Multitarget Gene Fine-Tuning for N -Acetylneuraminic Acid Production in Escherichia coli with Sole Carbon Source Glucose. Journal of Agricultural and Food Chemistry.DOI
Jingya Liu, Laichuang Han, Jianghua Li, Guocheng Du, Guoqiang Zhang (2025). Modification of Flexible Regions for Enhanced Thermal Stability of Alkaline Amylase. Journal of Agricultural and Food Chemistry.DOI
Baoyuan Guo, Wenwen Yu, Xianhao Xu, Yujie Liu, Yanfeng Liu, Guocheng Du, Long Liu, Xueqin Lv (2025). Adaptively Evolved and Multiplexed Engineered Saccharomyces cerevisiae for Neutralizer-Free Production of l -Lactic Acid. Journal of Agricultural and Food Chemistry.DOI
Yuan Qian, Xuan Wang, Yang Liu, Yunpeng Wang, Jianghua Li, Guocheng Du, Xinrui Zhao, Jian Chen (2025). Enhancing heme import to synthesize active myoglobin and hemoglobin in Pichia pastoris. 3 Biotech.DOI
Ping Lin, Linpei Zhang, Guocheng Du, Jian Chen, Juan Zhang, Zheng Peng (2025). Construction of Saccharomyces cerevisiae Platform Strain for the Biosynthesis of Carotenoids and Apocarotenoids. Journal of Agricultural and Food Chemistry.DOI
K.-H. Liu, Cuiping Pang, Qinghua Li, Jianghua Li, Guocheng Du, Guoqiang Zhang (2025). Step Enzymatic Hydrolysis and In Silico Screening-Assisted Preparation of Bioactive Peptides from Abalone. Foods.DOI
Chixiang Sun, Yongchao Wang, Baodong Hu, Jianan Wang, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Binju Wang, Xinrui Zhao (2025). Establishing an Efficient Electron Transfer System for P450 Enzyme OleP to Improve the Biosynthesis of Murideoxycholic Acid by Redox Partner Engineering. Angewandte Chemie.DOI
Fan Liu, Yunpeng Wang, Yijie Wang, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2025). Efficient synthesis of high-active multi-subunit hemoglobins through balanced expression of globins and robust heme-supply in Saccharomyces cerevisiae. Bioresource Technology.DOI
Jiaheng Liu, Yanfeng Liu, Xianhao Xu, Yaokang Wu, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Xueqin Lv, Long Liu (2025). Multiplexed engineering of cytochrome P450 enzymes for promoting terpenoid synthesis in Saccharomyces cerevisiae cell factories: A review. Biotechnology Advances.DOI
Yang Cheng, Wenwen Yu, Xinyu Bi, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Xueqin Lv, Long Liu (2025). CarveAdornCurate: a versatile cloud-based platform for constructing multiscale metabolic models. Trends in biotechnology.DOI
Fan Liu, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2025). Precise Engineering and Efficient Biosynthesis of Robust and High‐Activity Human Haemoglobin for Artificial Oxygen Carriers. Microbial Biotechnology.DOI
Baodong Hu, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Fang Zhong, Yucheng Zhao, Xinrui Zhao (2025). Efficient Biosynthesis of Furanocoumarin Intermediate Marmesin by Engineered Escherichia coli. ACS Synthetic Biology.DOI
Zihan Zhang, Baodong Hu, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2025). Construction of a Plasmid-Free Escherichia coli Strain with Enhanced Heme Supply to Produce Active Hemoglobins. Metabolites.DOI
Hao Xu, Wenwen Yu, Xuan Zhou, Jiaheng Liu, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu, Xueqin Lv (2025). Engineering Saccharomyces cerevisiae for improving itaconic acid production. Systems Microbiology and Biomanufacturing.DOI
Yiwei Zhao, Xiaohui Wu, Zhitong Zhou, Guocheng Du, Jian She Chen, Xiao Liu (2025). Comparative evaluation of antioxidant activity and protein digestion of plant-based milk from different sources under dynamic in vitro digestion models. Food Bioscience.DOI
Yuan Qian, Guijiang Liang, Junli Dong, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Jie Chen, Zhaojun Wang, Xinrui Zhao (2025). Effect of myoglobin on the flavor, color and texture of high-moisture soy protein concentrate -wheat gluten extrudates. Food Chemistry.DOI
Weiran Chu, Rongzhen Tian, Yaxin Guo, Yaokang Wu, Fabian B. H. Rehm, Long Liu, Jianghua Li, Guocheng Du, Jian Chen, Yanfeng Liu (2025). An evolved, orthogonal ssDNA generator for targeted hypermutation of multiple genomic loci. Nucleic Acids Research.DOI
Danni Sun, Yunpeng Wang, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2025). Modifications of Constitutive Promoter to Large-Scale Synthesize Porcine Myoglobin in Komagataella phaffii. Fermentation.DOI
Yang Li, Yaokang Wu, Yaokang Wu, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu, Yanfeng Liu, Long Liu (2025). A cross-species inducible system for enhanced protein expression and multiplexed metabolic pathway fine-tuning in bacteria. Nucleic Acids Research.DOI
Guanyi Qu, Yunfei Song, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu, Yangyang Li, Xueqin Lv (2025). De novo biosynthesis of mogroside V by multiplexed engineered yeasts. Metabolic Engineering.DOI
Xiangnan Xu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Rodrigo Ledesma‐Amaro, Long Liu (2025). CRISPR/Cas13X-assisted programmable and multiplexed translation regulation for controlled biosynthesis. Nucleic Acids Research.DOI
Haibo Yu, Yunpeng Wang, Yijie Wang, Yueheng Niu, Jingwen Zhou, Jianghua Li, Chen Jian, Guocheng Du, Xinrui Zhao (2025). Metabolic engineering of yeast to efficiently synthesize heme and hemoproteins: recent advance and prospects. FEMS Yeast Research.DOI
Yilin Zheng, Ruirui Xu, Yang Wang, Chengge Fang, Guo-Cheng Du, Zhen Kang (2024). [Heterologous expression of bacterial tyrosinase and its applications in biological hair dyeing and DOPA modification of hydrolyzed silk fibroin]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology.DOI
Xin-Wei Gao, Hong-Kang Zhu, Li-Tao Hu, Jieyu Sun, Wenjie Zuo, Ping Liu, Yang Wang, Guo-Cheng Du, Zhen Kang (2024). Characterization of the effects of hyaluronan oligosaccharides on human gut microbiota using a simulated batch fermentation system. Food Science and Human Wellness.DOI
Fengling Yang, Xiaoyuan Sun, Jie Lu, Linpei Zhang, Guo-Cheng Du, Jiang-Hua Li, Ruirui Xu, Zhen Kang (2024). Immobilized high-performance heparin lyase III for efficient preparation of low molecular weight heparin. International Journal of Biological Macromolecules.DOI
Liu Yang, Yang Liu, Yaokang Wu, Xueqin Lv, Ku Li, Jian Xiong, Xiao Liu, Jianghua Li, Long Liu, Guocheng Du, Jian Chen, Yanfeng Liu, Yanfeng Liu (2024). Improving Cellular Protein Content of Saccharomyces cerevisiae Based on Adaptive Evolution and Flow Cytometry-Aided High Throughput Screening. Journal of Agricultural and Food Chemistry.DOI
Qinghua Li, Chen Zhang, Jianghua Li, Guocheng Du, Zhaofeng Li, Jingwen Zhou, Guoqiang Zhang (2024). Characterization of Aspergillus oryzae mutant and its application in heterologous lipase expression. Synthetic and Systems Biotechnology.DOI
Yangyang Li, Yu Li, Zihe Lin, Shaoxiong Shen, Ruirui Xu, Wenwen Yu, Jingwen Zhou, Jianghua Li, Song Liu, Guocheng Du (2024). Heterologous expression of a highly thermostable L-asparaginase from Thermococcus zilligii in Aspergillus niger for efficient reduction of acrylamide in French fries. International Journal of Biological Macromolecules.DOI
Yanting Cao, Jianghua Li, Long Liu, Guocheng Du, Yanfeng Liu (2024). Harnessing microbial heterogeneity for improved biosynthesis fueled by synthetic biology. Synthetic and Systems Biotechnology.DOI
Jiaheng Liu, Minxia Song, Xianhao Xu, Yaokang Wu, Yanfeng Liu, Guocheng Du, Jianghua Li, Long Liu, Xueqin Lv (2024). Multiple metabolic engineering of Saccharomyces cerevisiae for the production of lycopene. Food Bioengineering.DOI
Ziqi Ye, Xianhao Xu, Yaokang Wu, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu, Xueqin Lv (2024). Efficient 7-Dehydrocholesterol Production by Multiple Metabolic Engineering of Diploid Saccharomyces cerevisiae. Journal of Agricultural and Food Chemistry.DOI
Jiayuan Wang, Laichuang Han, Maofang Teng, Qinghua Li, Jingwen Zhou, Jianghua Li, Guocheng Du, Guoqiang Zhang (2024). Maltose gradient-induced biosensor-based high-throughput screening for directed evolution of maltogenic amylase from Bacillus stearothermophilus. International Journal of Biological Macromolecules.DOI
Zhaoxiang Wang, Kangkang Chen, Song Liu, Jianghua Li, Guocheng Du (2024). Engineering the C-Terminal Region to Enhance the Thermal Stability of Streptomyces hygroscopicus Transglutaminase. Catalysts.DOI
Bin Wang, Yaokang Wu, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Jian Chen, Yanfeng Liu (2024). Synergistic regulation of chassis cell growth and screening of promoters, signal peptides and fusion protein linkers for enhanced recombinant protein expression in Bacillus subtilis. International Journal of Biological Macromolecules.DOI
Xinyu Bi, Yang Cheng, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Long Liu (2024). A Multi‐Omics, Machine Learning‐Aware, Genome‐Wide Metabolic Model of Bacillus Subtilis Refines the Gene Expression and Cell Growth Prediction. Advanced Science.DOI
Weiran Chu, Yaxin Guo, Yaokang Wu, Xueqin Lv, Jianghua Li, Long Liu, Guocheng Du, Jian Chen, Yanfeng Liu (2024). Enhancing Cellular and Enzymatic Properties Through In Vivo Continuous Evolution. ChemBioChem.DOI
Xin Guan, Zhuocheng Fei, Luyi Wang, Guohui Ji, Guocheng Du, Zhenwu Ma, Jingwen Zhou (2024). Engineered streaky pork by 3D co-printing and co-differentiation of muscle and fat cells. Food Hydrocolloids.DOI
Xiaomin Dong, Ying Chih Lin, Jianing Zhang, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Yanfeng Liu (2024). Modification of the Endoplasmic Reticulum to Enhance Ovalbumin Secretion in Saccharomyces cerevisiae. Journal of Agricultural and Food Chemistry.DOI
Zheng Peng, Hanlin Zhou, Zhijun Zhao, Chengjian Wu, Guocheng Du, Jian Chen, Juan Zhang (2024). Enzymatic quality enhancement of oolong tea based on grade difference analysis. Food Bioscience.DOI
Shufang Tian, Yanbin Li, Guocheng Du, Qingtao Liu (2024). Effect of cultures of synthetic starters on the flavour and ethyl carbamate content of rice wine. International Journal of Food Science & Technology.DOI
Xian Liang Sun, Xinyu Bi, Guyue Li, Shixiu Cui, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2024). Combinatorial metabolic engineering of Bacillus subtilis for menaquinone‐7 biosynthesis. Biotechnology and Bioengineering.DOI
Bo Zeng, Yishan Fu, Jiacai Ye, Penghui Yang, Cui Shixiu, Wenxuan Qiu, Yangyang Li, Taoxu Wu, Haiyun Zhang, Yachan Wang, Guocheng Du, Song Liu (2024). Ancestral sequence reconstruction of the prokaryotic three-domain laccases for efficiently degrading polyethylene. Journal of Hazardous Materials.DOI
Yuting Zhang, Yang Li, Yaokang Wu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2024). [The expression and secretion of human lactoferrin in Bacillus subtilis]. PubMed.DOI
Sahibzada Muhammad Aqeel, Abdulqader Al‐Adeeb, Guocheng Du, Song Liu (2024). Integrated strategies for efficient production of Streptomyces mobaraensis transglutaminase in Komagataella phaffii. International Journal of Biological Macromolecules.DOI
Lingtong Liao, Xiuru Shen, Zhiyu Shen, Guocheng Du, Jianghua Li, Guoqiang Zhang (2024). CRISPR/Cas9-Based Genome Editing for Protein Expression and Secretion in Kluyveromyces lactis. ACS Synthetic Biology.DOI
Zhihang Zhang, Yangyang Li, Zhenmin Liu, Shixiu Cui, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2024). Efficient secretory expression of human milk Osteopontin in Komagataella phaffii. Future Foods.DOI
Fan Liu, Xiaoyan Sun, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2024). Efficient biosynthesis of active hemoglobins through enhancing the import of heme in Saccharomyces cerevisiae. FEBS Journal.DOI
Huiyuan Huang, Wenwen Yu, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2024). Combinatorial Engineering of Escherichia coli for Enhancing 3-Fucosyllactose Production. ACS Synthetic Biology.DOI
Fei Yu, Chenyang Li, Tao Zhang, Zhou Jingwen, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2024). Developing a novel heme biosensor to produce high-active hemoproteins in Pichia pastoris through comparative transcriptomics. Metabolic Engineering.DOI
Qi Chen, Xiangnan Xu, Zhengyan Sun, Yu Wang, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2024). Metabolic engineering of Bacillus subtilis for de novo synthesis of 6′-sialyllactose. Systems Microbiology and Biomanufacturing.DOI
Mei Tang, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2024). Combinatorial Metabolic Engineering for Improving Betulinic Acid Biosynthesis in Saccharomyces cerevisiae. ACS Synthetic Biology.DOI
Yangyang Li, Haiyun Zhang, Yishan Fu, Zhitong Zhou, Wenwen Yu, Jingwen Zhou, Jianghua Li, Guocheng Du, Song Liu (2024). Enhancing Acid Resistance of Aspergillus niger Pectin Lyase through Surface Charge Design for Improved Application in Juice Clarification. Journal of Agricultural and Food Chemistry.DOI
Zihan Zhang, Baodong Hu, Tao Zhang, Zhengshan Luo, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2024). The modification of heme special importer to improve the production of active hemoglobins in Escherichia coli. Biotechnology Letters.DOI
Jia Li, Qinan Shao, Yulong Xiang, Jianghua Li, Jian Chen, Guocheng Du, Zhen Kang, Yang Wang (2024). High‐activity recombinant human carboxypeptidase B expression in Pichia pastoris through rational protein engineering and enhancing secretion from the Golgi apparatus to the plasma membrane. Biotechnology Journal.DOI
Runzhi Zhao, Rongzhen Tian, Yaokang Wu, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Jian Chen, Yanfeng Liu (2024). Optimization of linear plasmid expression system for protein production and secretion in Bacillus thuringiensis. Systems Microbiology and Biomanufacturing.DOI
Jinning Yang, Yaokang Wu, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Yanfeng Liu (2024). Engineering Redox Cofactor Balance for Improved 5-Methyltetrahydrofolate Production in Escherichia coli. Journal of Agricultural and Food Chemistry.DOI
Haoyu Guo, Rongzhen Tian, Yaokang Wu, Xueqin Lv, Jianghua Li, Long Liu, Guocheng Du, Jian Chen, Yanfeng Liu (2024). Facilitating stable gene integration expression and copy number amplification in Bacillus subtilis through a reversible homologous recombination switch. Synthetic and Systems Biotechnology.DOI
Qiu Tao, Guocheng Du, Jian Chen, Juan Zhang, Zheng Peng (2024). Metabolic Engineering for Efficient Synthesis of Patchoulol in Saccharomyces cerevisiae. Fermentation.DOI
Weijiao Zhang, Ping Zhang, Hao Wang, Ruirui Xu, Zhuan Xie, Yang Wang, Guocheng Du, Zhen Kang (2024). Enhancing the expression of chondroitin 4-O-sulfotransferase for one-pot enzymatic synthesis of chondroitin sulfate A. Carbohydrate Polymers.DOI
Chenyang Li, Tao Zhang, Zhengshan Luo, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2024). Efficient Secretory Expression for Mammalian Hemoglobins in Pichia pastoris. Fermentation.DOI
Cheng Liu, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Jian Chen, Yanfeng Liu (2024). Constructing an Antibiotic-Free Protein Expression System for Ovalbumin Biosynthesis in Probiotic Escherichia coli Nissle 1917. Journal of Agricultural and Food Chemistry.DOI
Wenqiu Wang, Yulong Xiang, Guobin Yin, Shan Hu, Jian Cheng, Jian Chen, Guocheng Du, Zhen Kang, Yang Wang (2024). Construction of 5-Aminolevulinic Acid Microbial Cell Factories through Identification of Novel Synthases and Metabolic Pathway Screens and Transporters. Journal of Agricultural and Food Chemistry.DOI
Tong Liu, Qingqing Cao, Fan Yang, Jianjun Lu, Xianglian Zeng, Jianghua Li, Guocheng Du, Huabin Tu, Yanfeng Liu (2024). Multi-Omics Analysis of the Co-Regulation of Wood Alcohol Accumulation in Baijiu Fermentation. Fermentation.DOI
Jiangong Lu, Xueqin Lv, Wenwen Yu, Jianing Zhang, Jianxing Lu, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Long Liu (2024). Reshaping Phosphatase Substrate Preference for Controlled Biosynthesis Using a “Design–Build–Test–Learn” Framework. Advanced Science.DOI
Maofang Teng, Shujie Ma, Yuanyang Zou, Jingwen Zhou, Jianghua Li, Guocheng Du, Guoqiang Zhang (2024). Molecular modification and food-grade system construction for protein-glutaminase production in Bacillus subtilis. Food Bioscience.DOI
Chao Liao, Xianhao Xu, Huiyuan Huang, Ruoqing Yang, Xuewen Zhu, Ke Jin, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2024). Construction of a plasmid-free Escherichia coli strain for lacto-N-neotetraose biosynthesis. Systems Microbiology and Biomanufacturing.DOI
Jialian Li, Yanlai Liu, Litao Hu, Ruirui Xu, Weijiao Zhang, Shan Hu, Yang Wang, Guocheng Du, Zhen Kang (2024). Construction of immobilized enzyme cascades for the biosynthesis of nucleotide sugars UDP-N-acetylglucosamine and UDP-glucuronic acid. Systems Microbiology and Biomanufacturing.DOI
Zirui Yin, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2024). The High-Throughput Screening of Microorganisms to Eliminate Ethyl Carbamate in Chinese Liquor. Foods.DOI
Yiyun Huang, Jingwen Zhou, Jianghua Li, Guocheng Du, Jian Chen, Xinrui Zhao (2024). Efficient Secretory Expression of Leghemoglobin in Saccharomyces cerevisiae. Fermentation.DOI
Ziwei Wang, Jingwen Zhou, Jianghua Li, Guocheng Du, Jian Chen, Xinrui Zhao (2024). Rational Design of Key Enzymes to Efficiently Synthesize Phycocyanobilin in Escherichia coli. Biomolecules.DOI
Xintong Xi, Weijiao Zhang, Litao Hu, Ruirui Xu, Yang Wang, Guocheng Du, Jian Chen, Zhen Kang (2024). Enzymatic construction of a library of even- and odd-numbered heparosan oligosaccharides and their N-sulfonated derivatives. International Journal of Biological Macromolecules.DOI
Yang Mo Gu, Yaru Jiang, Changfan Li, Jiang Zhu, Xueyao Lu, Jianyue Ge, Mengchen Hu, Jieying Deng, Jingbo Ma, Zhiliang Yang, Xiao‐Man Sun, Feng Xue, Guocheng Du, Peng Xu, He Huang (2024). High titer production of gastrodin enabled by systematic refactoring of yeast genome and an antisense-transcriptional regulation toolkit. Metabolic Engineering.DOI
Ying Chih Lin, Xiaomin Dong, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Jian Chen, Yanfeng Liu (2024). Construction of short synthetic promoters for optimization of ovalbumin expression level in Saccharomyces cerevisiae. Systems Microbiology and Biomanufacturing.DOI
Shan Hu, Siyan Zhou, Yang Wang, Wuxia Chen, Guobin Yin, Jian Chen, Guocheng Du, Zhen Kang (2024). Coordinated optimization of the polymerization and transportation processes to enhance the yield of exopolysaccharide heparosan. Carbohydrate Polymers.DOI
Jingya Fan, Jian Chen, Guocheng Du, Fang Fang (2024). Mechanism of lactic acid synthesis during strong-flavor baijiu fermentation revealed by transcriptomic analysis. Food Bioscience.DOI
Jiacai Ye, Penghui Yang, Jingwen Zhou, Guocheng Du, Song Liu (2024). Efficient Production of a Thermostable Mutant of Transglutaminase by Streptomyces mobaraensis. Journal of Agricultural and Food Chemistry.DOI
Yangyang Li, Cen Li, Yishan Fu, Quan Zhang, Jianing Ma, Jingwen Zhou, Jianghua Li, Guocheng Du, Song Liu (2024). A CRISPR/Cas9-based visual toolkit enabling multiplex integration at specific genomic loci in Aspergillus niger. Synthetic and Systems Biotechnology.DOI
Anqi Peng, Guobin Yin, Wenjie Zuo, Luyao Zhang, Guocheng Du, Jian Chen, Yang Wang, Zhen Kang (2024). Regulatory RNAs in Bacillus subtilis: A review on regulatory mechanism and applications in synthetic biology. Synthetic and Systems Biotechnology.DOI
Siyan Zhou, Linlin Zhao, Wenjie Zuo, Yilin Zheng, Ping Zhang, Yanan Sun, Yang Wang, Guocheng Du, Zhen Kang (2024). Minimizing endogenous cryptic plasmids to construct antibiotic-free expression systems for Escherichia coli Nissle 1917. Synthetic and Systems Biotechnology.DOI
Shuaili Chen, Zhanhao Yang, Zeyuan Zhong, Shiqin Yu, Jingwen Zhou, Jianghua Li, Guocheng Du, Guoqiang Zhang (2024). Ultrahigh-throughput screening-assisted in vivo directed evolution for enzyme engineering. Biotechnology for Biofuels and Bioproducts.DOI
Jiaxuan Wang, Cuiping Pang, Zhonglin Tu, Jianghua Li, Guocheng Du, Guoqiang Zhang (2024). Double enzymes coupled screening assisted molecular modification of α-Amino acid ester acyltransferase for L-Alanyl-l-Glutamine biosynthesis. Food Bioscience.DOI
Fei Yu, Ziwei Wang, Zihan Zhang, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2024). Biosynthesis, acquisition, regulation, and upcycling of heme: recent advances. Critical Reviews in Biotechnology.DOI
Jianbin Chen, Weigao Wang, Lian Wang, Huijing Wang, Minglong Hu, Jingwen Zhou, Guocheng Du, Weizhu Zeng (2023). Efficient De Novo Biosynthesis of Curcumin in Escherichia coli by Optimizing Pathway Modules and Increasing the Malonyl-CoA Supply. Journal of Agricultural and Food Chemistry.DOI
Xueqin Lv, Yuting Zhang, Lingrui Wang, Shixiu Cui, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu (2023). Expression and antimicrobial activity of the recombinant bovine lactoferricin in Pichia pastoris. Synthetic and Systems Biotechnology.DOI
Guangyao Hu, Yajuan Wang, Jian Chen, Guocheng Du, Fang Fang (2023). Synergistic fermentation with functional bacteria for production of salt-reduced soy sauce with enhanced aroma and saltiness. Food Bioscience.DOI
Qinghua Li, Jinchang Lu, Jingya Liu, Jianghua Li, Guoqiang Zhang, Guocheng Du, Jian Chen (2023). High-throughput droplet microfluidics screening and genome sequencing analysis for improved amylase-producing Aspergillus oryzae. Biotechnology for Biofuels and Bioproducts.DOI
Chixiang Sun, Baodong Hu, Yanchun Li, Zhimeng Wu, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Xinrui Zhao (2023). Efficient stereoselective hydroxylation of deoxycholic acid by the robust whole-cell cytochrome P450 CYP107D1 biocatalyst. Synthetic and Systems Biotechnology.DOI
Ruirui Xu, Weijao Zhang, Xintong Xi, Jiamin Chen, Yang Wang, Guocheng Du, Jianghua Li, Jian Chen, Zhen Kang (2023). Engineering sulfonate group donor regeneration systems to boost biosynthesis of sulfated compounds. Nature Communications.DOI
Yaokang Wu, Yang Li, Yuting Zhang, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2023). Efficient Protein Expression and Biosynthetic Gene Cluster Regulation in Bacillus subtilis Driven by a T7-BOOST System. ACS Synthetic Biology.DOI
Mengting Deng, Yaokang Wu, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Jian Chen, Yanfeng Liu (2023). Heterologous Single-Strand DNA-Annealing and Binding Protein Enhance CRISPR-Based Genome Editing Efficiency in Komagataella phaffii. ACS Synthetic Biology.DOI
Guanyi Qu, Yanfeng Liu, Qinyuan Ma, Jianghua Li, Guocheng Du, Long Liu, Xueqin Lv (2023). Progress and Prospects of Natural Glycoside Sweetener Biosynthesis: A Review. Journal of Agricultural and Food Chemistry.DOI
Xueqin Lv, Yang Li, Xiang Xiu, Chao Liao, Yameng Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu (2023). CRISPR genetic toolkits of classical food microorganisms: Current state and future prospects. Biotechnology Advances.DOI
Qi Zhu, Liangqiang Chen, Xiuxin Pu, Guocheng Du, Fan Yang, Jianjun Lu, Zheng Peng, Juan Zhang, Huabin Tu (2023). The Differences in the Composition of Maillard Components between Three Kinds of Sauce-Flavor Daqu. Fermentation.DOI
Xueqin Lv, Ke Jin, Yi Yu, Lingang Song, Xiang Xiu, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Long Liu (2023). Analysis of acid-tolerance mechanism based on membrane microdomains in Saccharomyces cerevisiae. Microbial Cell Factories.DOI
Daoan Wang, Litao Hu, Ruirui Xu, Weijiao Zhang, Haibo Xiong, Yang Wang, Guocheng Du, Zhen Kang (2023). Production of different molecular weight glycosaminoglycans with microbial cell factories. Enzyme and Microbial Technology.DOI
Weijiao Zhang, Ruirui Xu, Jiamin Chen, Haibo Xiong, Yang Wang, Bo Pang, Guocheng Du, Zhen Kang (2023). Advances and challenges in biotechnological production of chondroitin sulfate and its oligosaccharides. International Journal of Biological Macromolecules.DOI
Fei Yu, Xinrui Zhao, Jingwen Zhou, Wei Lü, Jianghua Li, Jian Chen, Guocheng Du (2023). Biosynthesis of High‐Active Hemoproteins by the Efficient Heme‐Supply Pichia Pastoris Chassis. Advanced Science.DOI
Yadi Ma, Cuiping You, Guoqiang Zhang, Jianghua Li, Guocheng Du (2023). [Improving the position specificity of Themomyces lanuginosus lipase based on semi-rational design]. PubMed.DOI
Jingya Fan, Guanyi Qu, Datao Wang, Jian Chen, Guocheng Du, Fang Fang (2023). Synergistic Fermentation with Functional Microorganisms Improves Safety and Quality of Traditional Chinese Fermented Foods. Foods.DOI
Xiangnan Xu, Xueqin Lv, Shixiu Cui, Yanfeng Liu, Hongzhi Xia, Jianghua Li, Guocheng Du, Zhaofeng Li, Rodrigo Ledesma‐Amaro, Jian Chen, Long Liu (2023). Remodeling Isoprene Pyrophosphate Metabolism for Promoting Terpenoids Bioproduction. Engineering.DOI
Rongzhen Tian, Runzhi Zhao, Haoyu Guo, Kun Yan, Chenyun Wang, Cheng Lu, Xueqin Lv, Jianghua Li, Long Liu, Guocheng Du, Jian Chen, Yanfeng Liu (2023). Engineered bacterial orthogonal DNA replication system for continuous evolution. Nature Chemical Biology.DOI
Jiaqi Sun, Yanting Cao, Xueqin Lü, Jianghua Li, Long Liu, Guocheng Du, Jian Chen, Yanfeng Liu (2023). [Development of biosensors highly responsive to N-acetylneuraminic acid in Bacillus subtilis]. PubMed.DOI
Yajun Dong, Shixiu Cui, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lü, Long Liu (2023). [Functional analysis of functional membrane microdomains in the biosynthesis of menaquinone-7]. PubMed.DOI
Mengting Deng, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Jian Chen, Yanfeng Liu (2023). Cell factory-based milk protein biomanufacturing: Advances and perspectives. International Journal of Biological Macromolecules.DOI
Qingzi Lei, Jun Ma, Guocheng Du, Jingwen Zhou, Xin Guan (2023). Efficient expression of a cytokine combination in Saccharomyces cerevisiae for cultured meat production. Food Research International.DOI
Xiao Kong, Yaokang Wu, Wenwen Yu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2023). Efficient Synthesis of Limonene in Saccharomyces cerevisiae Using Combinatorial Metabolic Engineering Strategies. Journal of Agricultural and Food Chemistry.DOI
Xuan Wang, Xianhao Xu, Jiaheng Liu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2023). Metabolic Engineering of Saccharomyces cerevisiae for Efficient Retinol Synthesis. Journal of Fungi.DOI
Yexu Wu, Senlin Lei, Chuanchuan Lu, Jianghua Li, Guocheng Du, Yanfeng Liu (2023). Enhanced Ribonucleic Acid Production by High-Throughput Screening Based on Fluorescence Activation and Transcriptomic-Guided Fermentation Optimization in Saccharomyces cerevisiae. Journal of Agricultural and Food Chemistry.DOI
Peilin Wang, Ruirui Xu, Linlin Zhao, Yang Wang, Guocheng Du, Jian Chen, Zhen Kang (2023). Construction of a Protein Crystalline Inclusion-Based Enzyme Immobilization System for Biosynthesis of PAPS from ATP and Sulfate. ACS Synthetic Biology.DOI
Penghui Yang, Xinglong Wang, Jiacai Ye, Shengqi Rao, Jingwen Zhou, Guocheng Du, Song Liu (2023). Enhanced Thermostability and Catalytic Activity of Streptomyces mobaraenesis Transglutaminase by Rationally Engineering Its Flexible Regions. Journal of Agricultural and Food Chemistry.DOI
Yong-Lian Zhu, Yaokang Wu, Wenwen Yu, Quanwei Zhang, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2023). Engineering Bacillus subtilis for efficient production of 3′-sialyllactose. Systems Microbiology and Biomanufacturing.DOI
Meng Chai, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2023). Combinatorial Protein Engineering and Metabolic Engineering for Efficient Synthesis of l -Histidine in Corynebacterium glutamicum. ACS Synthetic Biology.DOI
Tiantian Liu, Sun Li, Cheng Zhang, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2023). Combinatorial metabolic engineering and process optimization enables highly efficient production of L-lactic acid by acid-tolerant Saccharomyces cerevisiae. Bioresource Technology.DOI
Lizhi Liao, Hao Huang, Yang Wang, Guocheng Du, Zhen Kang (2023). Yeast surface display of leech hyaluronidase for the industrial production of hyaluronic acid oligosaccharides. Engineering Microbiology.DOI
Yameng Xu, Luyao Han, Cheng Yang, Yonglin Zhang, Yaokang Wu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2023). ATP-Binding Cassette Exporter PDR11-Mediated Terpenoid Secretion in Engineered Yeast. ACS Synthetic Biology.DOI
Qi Zhou, Yaokang Wu, Jieying Deng, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2023). Combinatorial metabolic engineering enables high yield production of α-arbutin from sucrose by biocatalysis. Applied Microbiology and Biotechnology.DOI
Yangyang Li, Cen Li, Sahibzada Muhammad Aqeel, Yachan Wang, Quan Zhang, Jianing Ma, Jingwen Zhou, Jianghua Li, Guocheng Du, Song Liu (2023). Enhanced expression of xylanase in Aspergillus niger enabling a two-step enzymatic pathway for extracting β-glucan from oat bran. Bioresource Technology.DOI
Luyao Han, Yaokang Wu, Yameng Xu, Chenyang Zhang, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2023). Engineered Saccharomyces cerevisiae for de novo δ-tocotrienol biosynthesis. Systems Microbiology and Biomanufacturing.DOI
Peng Wen, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Yanfeng Liu (2023). Crude enzyme immobilization-based cell-free system for efficient N-acetylneuraminic acid biosynthesis aided by N-terminal coding sequence screening. Systems Microbiology and Biomanufacturing.DOI
Litao Hu, Yang Wang, Lingling Wang, Sen Xiao, Yilin Zheng, Guobin Yin, Guocheng Du, Jian Chen, Zhen Kang (2023). Construction of Osmotic Pressure Responsive Vacuole-like Bacterial Organelles with Capsular Polysaccharides as Building Blocks. ACS Synthetic Biology.DOI
Jiaheng Liu, Xinglong Wang, Ke Jin, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2023). In Silico Prediction and Mining of Exporters for Secretory Bioproduction of Terpenoids in Saccharomyces cerevisiae. ACS Synthetic Biology.DOI
Shujie Ma, Xiao Liu, Jingwen Zhou, Yuanxia Sun, Guoqiang Zhang, Jianghua Li, Guocheng Du (2023). Characterization of high internal phase emulsions stabilized by protein glutaminase-deamidated wheat gluten. LWT.DOI
Shufang Tian, Yanbin Li, Yudong Li, Guocheng Du (2023). Effect of two starters (Jiu Yao) on Chinese rice wine microbial community and flavour. International Journal of Food Science & Technology.DOI
Xinrui Zhao, Haibo Yu, Qingfeng Liang, Jingwen Zhou, Jianghua Li, Guocheng Du, Jian Chen (2023). Stepwise Optimization of Inducible Expression System for the Functional Secretion of Horseradish Peroxidase in Saccharomyces cerevisiae. Journal of Agricultural and Food Chemistry.DOI
Xinying Wu, Wen Cai, Pengcheng Zhu, Zheng Peng, Tianfei Zheng, Dongliang Li, Jianghua Li, Guanyu Zhou, Juan Zhang, Guocheng Du (2023). Function-driven design of Bacillus kochii and Filobasidium magnum co-culture to improve quality of flue-cured tobacco. Frontiers in Microbiology.DOI
Yuhang Di, Jianghua Li, Jian Chen, Xinrui Zhao, Guocheng Du (2023). Simulation and Control of the Formation of Ethyl Carbamate during the Fermentation and Distillation Processes of Chinese Baijiu. Foods.DOI
Baodong Hu, Xinrui Zhao, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du (2023). Efficient hydroxylation of flavonoids by using whole-cell P450 sca-2 biocatalyst in Escherichia coli. Frontiers in Bioengineering and Biotechnology.DOI
Xinyu Bi, Yang Cheng, Xianhao Xu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Rodrigo Ledesma‐Amaro, Long Liu (2023). et i Bsu1209: A comprehensive multiscale metabolic model for Bacillus subtilis. Biotechnology and Bioengineering.DOI
Qinghua Li, Jinchang Lu, Guoqiang Zhang, Jingwen Zhou, Jianghua Li, Guocheng Du, Jian Chen (2023). CRISPR/Cas9-Mediated Multiplexed Genome Editing in Aspergillus oryzae. Journal of Fungi.DOI
Xiuru Shen, Lingtong Liao, Guoqiang Zhang, Jingwen Zhou, Jianghua Li, Guocheng Du (2023). Characterization of putative mannoprotein in Kluyveromyces lactis for lactase production. Synthetic and Systems Biotechnology.DOI
Li Ying Sun, Quanwei Zhang, Xiao Kong, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Rodrigo Ledesma‐Amaro, Jian Chen, Long Liu (2023). Highly efficient neutralizer-free l-malic acid production using engineered Saccharomyces cerevisiae. Bioresource Technology.DOI
Yang Cheng, Xinyu Bi, Yameng Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2023). Machine learning for metabolic pathway optimization: A review. Computational and Structural Biotechnology Journal.DOI
Xintong Xi, Litao Hu, Hao Huang, Yang Wang, Ruirui Xu, Guocheng Du, Jian Chen, Zhen Kang (2023). Improvement of the stability and catalytic efficiency of heparan sulfate N-sulfotransferase for preparing N-sulfated heparosan. Journal of Industrial Microbiology & Biotechnology.DOI
Jike Xue, Jingwen Zhou, Jianghua Li, Guocheng Du, Jian Chen, Miao Wang, Xinrui Zhao (2022). Systematic engineering of Saccharomyces cerevisiae for efficient synthesis of hemoglobins and myoglobins. Bioresource Technology.DOI
Baodong Hu, Haibo Yu, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du, Sang Yup Lee, Xinrui Zhao (2022). Whole‐Cell P450 Biocatalysis Using Engineered Escherichia coli with Fine‐Tuned Heme Biosynthesis. Advanced Science.DOI
Xinyi Zhao, Jianghua Li, Guocheng Du, Jian Chen, Tingyue Ren, Junyan Wang, Ying Han, Zhen Pan, Xinrui Zhao (2022). The Influence of Seasons on the Composition of Microbial Communities and the Content of Lactic Acid during the Fermentation of Fen-Flavor Baijiu. Fermentation.DOI
Yang Cheng, Xinyu Bi, Yameng Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2022). Artificial intelligence technologies in bioprocess: Opportunities and challenges. Bioresource Technology.DOI
Chang Liu, Xueqin Lv, Jianghua Li, Long Liu, Guocheng Du, Yanfeng Liu (2022). Metabolic Engineering of Escherichia coli for Increased Bioproduction of N -Acetylneuraminic Acid. Journal of Agricultural and Food Chemistry.DOI
Qingmei Zhang, Guocheng Du, Jian Chen, Jianghua Li, Zongwei Qiao, Jia Zheng, Dong Zhao, Xinrui Zhao (2022). Systematic analysis of Baobaoqu fermentation starter for Wuliangye Baijiu by the combination of metagenomics and metabolomics. Frontiers in Microbiology.DOI
Yang Wang, Guobin Yin, Huanjiao Weng, Luyao Zhang, Guocheng Du, Jian Chen, Zhen Kang (2022). Gene knockdown by structure defined single-stem loop small non-coding RNAs with programmable regulatory activities. Synthetic and Systems Biotechnology.DOI
Guangyao Hu, Jian Chen, Guocheng Du, Fang Fang (2022). Moromi mash dysbiosis trigged by salt reduction is relevant to quality and aroma changes of soy sauce. Food Chemistry.DOI
Jinhua Yang, Zheng Peng, Xiaomei Ji, Juan Zhang, Guocheng Du (2022). Galactitol Transport Factor GatA Relieves ATP Supply Restriction to Enhance Acid Tolerance of Escherichia coli in the Two-Stage Fermentation Production of D-Lactate. Fermentation.DOI
Qiyang Yan, Zhuocheng Fei, Mei Li, Jingwen Zhou, Guocheng Du, Xin Guan (2022). Naringenin Promotes Myotube Formation and Maturation for Cultured Meat Production. Foods.DOI
Qi Zhu, Liangqiang Chen, Zheng Peng, Qiaoling Zhang, Wanqiu Huang, Fan Yang, Guocheng Du, Juan Zhang, Li Wang (2022). The differences in carbohydrate utilization ability between six rounds of Sauce-flavor Daqu. Food Research International.DOI
Guobin Yin, Anqi Peng, Luyao Zhang, Yang Wang, Guocheng Du, Jian Chen, Zhen Kang (2022). Design of artificial small regulatory trans-RNA for gene knockdown in Bacillus subtilis. Synthetic and Systems Biotechnology.DOI
Xueqin Lv, Wenwen Yu, Chenyang Zhang, Peng Ning, Jianghua Li, Yanfeng Liu, Guocheng Du, Long Liu (2022). C1-based biomanufacturing: Advances, challenges and perspectives. Bioresource Technology.DOI
Yameng Xu, Yaokang Wu, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Xueqin Lv, Long Liu (2022). Sustainable bioproduction of natural sugar substitutes: Strategies and challenges. Trends in Food Science & Technology.DOI
Jinhua Yang, Juan Zhang, Zhengming Zhu, Xinyi Jiang, Tianfei Zheng, Guocheng Du (2022). Revealing novel synergistic defense and acid tolerant performance of Escherichia coli in response to organic acid stimulation. Applied Microbiology and Biotechnology.DOI
Bo Pang, Hao Wang, Hao Huang, Lizhi Liao, Yang Wang, Miao Wang, Guocheng Du, Zhen Kang (2022). Enzymatic Production of Low-Molecular-Weight Hyaluronan and Its Oligosaccharides: A Review and Prospects. Journal of Agricultural and Food Chemistry.DOI
Guoyun Sun, Yaokang Wu, Ziyang Huang, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2022). Directed evolution of diacetylchitobiose deacetylase via high-throughput droplet sorting with a novel, bacteria-based biosensor. Biosensors and Bioelectronics.DOI
Cuiping Pang, Guoqiang Zhang, Song Liu, Jingwen Zhou, Jianghua Li, Guocheng Du (2022). Engineering sigma factors and chaperones for enhanced heterologous lipoxygenase production in Escherichia coli. Biotechnology for Biofuels and Bioproducts.DOI
Xueqin Lv, Xuan Zhou, Jun Ma, Mengrui Tao, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu (2022). Engineered Saccharomyces cerevisiae for the De Novo Biosynthesis of (−)-Menthol. Journal of Fungi.DOI
Yangyang Li, Weiyan Song, Xuyue Han, Yachan Wang, Shengqi Rao, Quan Zhang, Jingwen Zhou, Jianghua Li, Song Liu, Guocheng Du (2022). Recent progress in key lignocellulosic enzymes: Enzyme discovery, molecular modifications, production, and enzymatic biomass saccharification. Bioresource Technology.DOI
Cuiping Pang, Song Liu, Guoqiang Zhang, Jingwen Zhou, Guocheng Du, Jianghua Li (2022). Improving the catalytic efficiency of Pseudomonas aeruginosa lipoxygenase by semi-rational design. Enzyme and Microbial Technology.DOI
Yang Li, Yaokang Wu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2022). A genetic toolkit for efficient production of secretory protein in Bacillus subtilis. Bioresource Technology.DOI
Guoyun Sun, Ziyang Huang, Zhiqian Zhang, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2022). A Two-Step Cross-Linked Hydrogel Immobilization Strategy for Diacetylchitobiose Deacetylase. Catalysts.DOI
Xinying Wu, Wen Cai, Pengcheng Zhu, Zheng Peng, Tianfei Zheng, Dongliang Li, Jianghua Li, Guanyu Zhou, Guocheng Du, Juan Zhang (2022). Profiling the role of microorganisms in quality improvement of the aged flue-cured tobacco. BMC Microbiology.DOI
Jialian Li, Bo Wang, Jian Chen, Guocheng Du, Fang Fang (2022). Heme Dependent Catalase Conditionally Contributes to Oxygen Tolerance of Tetragenococcus halophilus Strains Isolated from Soy Sauce Moromi. Applied Sciences.DOI
Guoqiang Zhang, Maofang Teng, Song Liu, Jingwen Zhou, Jianghua Li, Guocheng Du (2022). [Directed evolution of maltose induced promoters with expanded gradient intensity]. PubMed.DOI
Jiangong Lu, Xinyu Bi, Yanfeng Liu, Xueqin Lv, Jianghua Li, Guocheng Du, Long Liu (2022). In silico cell factory design driven by comprehensive genome-scale metabolic models: development and challenges. Systems Microbiology and Biomanufacturing.DOI
Yangyang Li, Weiyan Song, Xiaoqiang Yin, Shengqi Rao, Quan Zhang, Jingwen Zhou, Jianghua Li, Guocheng Du, Song Liu (2022). Enhanced catalytic performance of thermophilic GH11 xylanase by fusing carbohydrate-binding module 9-2 and linker for better synergistic degradation of wheat bran. Process Biochemistry.DOI
Weijiao Zhang, Ruirui Xu, Xuerong Jin, Yang Wang, Litao Hu, Tianmeng Zhang, Guocheng Du, Zhen Kang (2022). Enzymatic Production of Chondroitin Oligosaccharides and Its Sulfate Derivatives. Frontiers in Bioengineering and Biotechnology.DOI
Litao Hu, Yang Wang, Yunxiao Hu, Juyi Yin, Lingling Wang, Guocheng Du, Jian Chen, Zhen Kang (2022). Biosynthesis of non-sulfated high-molecular-weight glycosaminoglycans and specific-sized oligosaccharides. Carbohydrate Polymers.DOI
Xiang Xiu, Yi Ning Sun, Yaokang Wu, Ke Jin, Lisha Qu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2022). Modular remodeling of sterol metabolism for overproduction of 7-dehydrocholesterol in engineered yeast. Bioresource Technology.DOI
Tianfei Zheng, Qianying Zhang, Qiaoyin Wu, Dongliang Li, Xinying Wu, Pinhe Li, Quanwei Zhou, Wen Cai, Juan Zhang, Guocheng Du (2022). Effects of Inoculation With Acinetobacter on Fermentation of Cigar Tobacco Leaves. Frontiers in Microbiology.DOI
Tiantian Liu, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2022). Engineered Microbial Cell Factories for Sustainable Production of L-Lactic Acid: A Critical Review. Fermentation.DOI
Tianfei Zheng, Qianying Zhang, Pinhe Li, Xinying Wu, Yi Liu, Zhen Yang, Dongliang Li, Juan Zhang, Guocheng Du (2022). Analysis of Microbial Community, Volatile Flavor Compounds, and Flavor of Cigar Tobacco Leaves From Different Regions. Frontiers in Microbiology.DOI
Quanwei Zhang, Zhenmin Liu, Hongzhi Xia, Ziyang Huang, Yong-Lian Zhu, Linfeng Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2022). Engineered Bacillus subtilis for the de novo production of 2′-fucosyllactose. Microbial Cell Factories.DOI
Yameng Xu, Xinglong Wang, Chenyang Zhang, Xuan Zhou, Xianhao Xu, Luyao Han, Xueqin Lv, Yanfeng Liu, Song Liu, Jianghua Li, Guocheng Du, Jian Chen, Rodrigo Ledesma‐Amaro, Long Liu (2022). De novo biosynthesis of rubusoside and rebaudiosides in engineered yeasts. Nature Communications.DOI
Siyu Wang, Xianhao Xu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu (2022). Construction and Optimization of the de novo Biosynthesis Pathway of Mogrol in Saccharomyces Cerevisiae. Frontiers in Bioengineering and Biotechnology.DOI
Ke Jin, Hongzhi Xia, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2022). Compartmentalization and transporter engineering strategies for terpenoid synthesis. Microbial Cell Factories.DOI
Tianfei Zheng, Qianying Zhang, Zheng Peng, Dongliang Li, Xinying Wu, Yi Liu, Pinhe Li, Juan Zhang, Guocheng Du (2022). Metabolite-based cell sorting workflow for identifying microbes producing carbonyls in tobacco leaves. Applied Microbiology and Biotechnology.DOI
Jingcheng Shi, Chaofan Duan, Bo Pang, Yang Wang, Guocheng Du, Zhen Kang (2022). Enhanced catalytic efficiency and substrate specificity of Streptomyces griseus trypsin by evolution-guided mutagenesis. Systems Microbiology and Biomanufacturing.DOI
Xinyu Bi, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2022). Construction of Multiscale Genome-Scale Metabolic Models: Frameworks and Challenges. Biomolecules.DOI
Bo Pang, Jing He, Weijiao Zhang, Hao Huang, Yang Wang, Miao Wang, Guocheng Du, Zhen Kang (2022). Active Expression of Human Hyaluronidase PH20 and Characterization of Its Hydrolysis Pattern. Frontiers in Bioengineering and Biotechnology.DOI
Zheng Peng, Xinzhe Mao, Wanmeng Mu, Guocheng Du, Jian Chen, Juan Zhang (2022). Modifying the Substrate Specificity of Keratinase for Industrial Dehairing to Replace Lime-Sulfide. ACS Sustainable Chemistry & Engineering.DOI
Xin Guan, Zihe Pan, Zhuoya Xu, Sidun Zhang, Haohao Tang, Guocheng Du, Jingwen Zhou (2022). Natural flavonoid luteolin promotes the differentiation of porcine myoblasts through activation of PI3K/Akt/mTOR signaling. Food Bioscience.DOI
Han Mo Yang, Jinning Yang, Cheng Liu, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Jian Chen, Yanfeng Liu (2022). High-Level 5-Methyltetrahydrofolate Bioproduction in Bacillus subtilis by Combining Modular Engineering and Transcriptomics-Guided Global Metabolic Regulation. Journal of Agricultural and Food Chemistry.DOI
Xinglong Wang, Beichen Zhao, Jianhui Du, Yameng Xu, Xuewen Zhu, Jingwen Zhou, Shengqi Rao, Guocheng Du, Jian Chen, Song Liu (2022). Active secretion of a thermostable transglutaminase variant in Escherichia coli. Microbial Cell Factories.DOI
Xuewen Zhu, Yaokang Wu, Xueqin Lv, Yanfeng Liu, Guocheng Du, Jianghua Li, Long Liu (2022). Combining CRISPR–Cpf1 and Recombineering Facilitates Fast and Efficient Genome Editing in Escherichia coli. ACS Synthetic Biology.DOI
Qi Zhu, Liangqiang Chen, Zheng Peng, Qiaoling Zhang, Wanqiu Huang, Fan Yang, Guocheng Du, Juan Zhang, Li Wang (2022). Analysis of environmental driving factors on Core Functional Community during Daqu fermentation. Food Research International.DOI
Suwei Li, Xianhao Xu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu (2022). Combinatorial Metabolic Engineering and Enzymatic Catalysis Enable Efficient Production of Colanic Acid. Microorganisms.DOI
Xiaoqiang Yin, Shengqi Rao, Jingwen Zhou, Guocheng Du, Jian Chen, Song Liu (2022). Improved Productivity of Streptomyces mobaraensis Transglutaminase by Regulating Zymogen Activation. Frontiers in Bioengineering and Biotechnology.DOI
Yangyang Li, Cen Li, Hao Huang, Shengqi Rao, Quan Zhang, Jingwen Zhou, Jianghua Li, Guocheng Du, Song Liu (2022). Significantly Enhanced Thermostability of Aspergillus niger Xylanase by Modifying Its Highly Flexible Regions. Journal of Agricultural and Food Chemistry.DOI
Cuiping Pang, Song Liu, Guoqiang Zhang, Jingwen Zhou, Guocheng Du, Jianghua Li (2022). Enhancing extracellular production of lipoxygenase in Escherichia coli by signal peptides and autolysis system. Microbial Cell Factories.DOI
Xin Guan, Qiyang Yan, Dandan Wang, Guocheng Du, Jingwen Zhou (2022). IGF-1 Signaling Regulates Mitochondrial Remodeling during Myogenic Differentiation. Nutrients.DOI
Jinhua Yang, Zheng Peng, Qi Zhu, Juan Zhang, Guocheng Du (2022). [NiFe] Hydrogenase Accessory Proteins HypB–HypC Accelerate Proton Conversion to Enhance the Acid Resistance and d -Lactic Acid Production of Escherichia coli. ACS Synthetic Biology.DOI
Deng Chen, Yaokang Wu, Xueqin Lv, Jianghua Li, Yanfeng Liu, Guocheng Du, Jian Chen, Long Liu (2022). Refactoring transcription factors for metabolic engineering. Biotechnology Advances.DOI
Shixiu Cui, Xueqin Lv, Guoyun Sun, Wen‐Yang Wu, Hong Xu, Yuelong Li, Yanfeng Liu, Jianghua Li, Guocheng Du, Miao Wang, Long Liu (2022). Recent advances and prospects in purification and heterologous expression of lactoferrin. Food Bioengineering.DOI
Li Wang, Yang Wang, Jianghua Li, Guocheng Du, Zhen Kang (2022). [Construction and optimization of ergothioneine-producing Escherichia coli]. PubMed.DOI
Yanfeng Liu, Mengchuang Wang, Fan Yang, Xiaolong Zhang, Jianghua Li, Guocheng Du, Li Wang, Jian Chen (2022). A CRISPR-Cas12a-Based Assay for Efficient Quantification of Lactobacillus panis in Chinese Baijiu Brewing Microbiome. Fermentation.DOI
Shufang Tian, Weizhu Zeng, Jingwen Zhou, Guocheng Du (2022). Correlation between the microbial community and ethyl carbamate generated during Huzhou rice wine fermentation. Food Research International.DOI
Mengting Deng, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Jian Chen, Yanfeng Liu (2022). Efficient Bioproduction of Human Milk Alpha-Lactalbumin in Komagataella phaffii. Journal of Agricultural and Food Chemistry.DOI
Shufang Tian, Weizhu Zeng, Xin Guan, Jingwen Zhou, Guocheng Du (2022). Effects of fortified starter culture containing Saccharomyces cerevisiae and Lactobacillus fermentum on microbial community structure and ethyl carbamate. Food Control.DOI
Lisha Qu, Xiang Xiu, Guoyun Sun, Chenyang Zhang, Haiquan Yang, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2022). Engineered yeast for efficient de novo synthesis of 7‐dehydrocholesterol. Biotechnology and Bioengineering.DOI
Baodong Hu, Xinrui Zhao, Endao Wang, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du (2022). Efficient heterologous expression of cytochrome P450 enzymes in microorganisms for the biosynthesis of natural products. Critical Reviews in Biotechnology.DOI
Qinghua Li, Jinchang Lu, Guoqiang Zhang, Song Liu, Jingwen Zhou, Guocheng Du, Jian Chen (2022). Recent advances in the development of Aspergillus for protein production. Bioresource Technology.DOI
Qingzi Lei, Mei Li, Guocheng Du, Jingwen Zhou, Xin Guan (2022). An effective cytokine combination for ex vivo expansion of porcine muscle stem cells. Food Bioscience.DOI
C. Wang, Wei Zhang, Rongzhen Tian, Jianing Zhang, Linpei Zhang, Zhaohong Deng, Xueqin Lv, Jianghua Li, Long Liu, Guocheng Du, Yanfeng Liu (2022). Model‐driven design of synthetic N‐terminal coding sequences for regulating gene expression in yeast and bacteria. Biotechnology Journal.DOI
Yanfeng Liu, Bing Wan, Fan Yang, Xiaolong Zhang, Jianghua Li, Guocheng Du, Li Wang, Jian Chen (2022). Metabolomics-Driven Elucidation of Interactions between Saccharomyces cerevisiae and Lactobacillus panis from Chinese Baijiu Fermentation Microbiome. Fermentation.DOI
Meixi Ling, Yaokang Wu, Rongzhen Tian, Yanfeng Liu, Wenwen Yu, Guanjun Tao, Xueqin Lv, Jianghua Li, Guocheng Du, Rodrigo Ledesma‐Amaro, Long Liu (2022). Combinatorial pathway engineering of Bacillus subtilis for production of structurally defined and homogeneous chitooligosaccharides. Metabolic Engineering.DOI
Ziyang Huang, Xueqin Lv, Guoyun Sun, Xinzhu Mao, Wei Lu, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu (2022). Chitin deacetylase: from molecular structure to practical applications. Systems Microbiology and Biomanufacturing.DOI
Shufang Tian, Weizhu Zeng, Fang Fang, Jingwen Zhou, Guocheng Du (2022). The microbiome of Chinese rice wine (Huangjiu). Current Research in Food Science.DOI
Yonglin Zhang, Yang Wang, Zhengxiong Zhou, Peilin Wang, Xintong Xi, Shan Hu, Ruirui Xu, Guocheng Du, Jianghua Li, Jian Chen, Zhen Kang (2022). Synthesis of bioengineered heparin by recombinant yeast Pichia pastoris. Green Chemistry.DOI
Fei Yu, Min Zhang, Junfeng Sun, Fang Wang, Xiangfei Li, Yan Liu, Zhou Wang, Xinrui Zhao, Jianghua Li, Jian Chen, Guocheng Du, Zhenglian Xue (2022). Improved Neomycin Sulfate Potency in Streptomyces fradiae Using Atmospheric and Room Temperature Plasma (ARTP) Mutagenesis and Fermentation Medium Optimization. Microorganisms.DOI
Jiahua Fang, Mei Li, Guoqiang Zhang, Guocheng Du, Jingwen Zhou, Xin Guan, Jian Chen (2022). Vitamin C enhances the ex vivo proliferation of porcine muscle stem cells for cultured meat production. Food & Function.DOI
Jiangong Lu, Yaokang Wu, Deng Chen, Yanfeng Liu, Xueqin Lv, Jianghua Li, Guocheng Du, Long Liu (2022). Model-based dynamic engineering of Escherichia coli for N-acetylglucosamine overproduction. Biotechnology Notes.DOI
Shi Cheng, Song Liu, Guocheng Du (2022). Improving Catalytic Activity and Thermal Stability of Methyl‐Parathion Hydrolase for Degrading the Pesticide of Methyl‐Parathion. International Journal of Chemical Engineering.DOI
Xin Guan, Jingwen Zhou, Guocheng Du, Jian Chen (2021). Bioprocessing technology of muscle stem cells: implications for cultured meat. Trends in biotechnology.DOI
Meng Chai, Deng Chen, Qi Chen, Wei Lu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2021). Synthetic Biology Toolkits and Metabolic Engineering Applied in Corynebacterium glutamicum for Biomanufacturing. ACS Synthetic Biology.DOI
Xiaolong Zhang, Chenyun Wang, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Miao Wang, Yanfeng Liu (2021). Engineering of Synthetic Multiplexed Pathways for High-Level N-Acetylneuraminic Acid Bioproduction. Journal of Agricultural and Food Chemistry.DOI
Hao Huang, Xiaodong Hou, Ruirui Xu, Zhiwei Deng, Yang Wang, Guocheng Du, Yijian Rao, Jian Chen, Zhen Kang (2021). Structure and cleavage pattern of a hyaluronate 3-glycanohydrolase in the glycoside hydrolase 79 family. Carbohydrate Polymers.DOI
Jinhua Yang, Juan Zhang, Zhengming Zhu, Guocheng Du (2021). The challenges and prospects of Escherichia coli as an organic acid production host under acid stress. Applied Microbiology and Biotechnology.DOI
Cen Li, Jingwen Zhou, Shengqi Rao, Guocheng Du, Song Liu (2021). Visualized Multigene Editing System for Aspergillus niger. ACS Synthetic Biology.DOI
Daoan Wang, Jiamin Chen, Yang Wang, Guocheng Du, Zhen Kang (2021). Engineering Escherichia coli for high-yield production of ectoine. Green Chemical Engineering.DOI
Xiumei Ni, Jian Chen, Guocheng Du, Fang Fang (2021). Food-grade expression of multicopper oxidase with improved capability in degrading biogenic amines. Systems Microbiology and Biomanufacturing.DOI
Xinying Wu, Pengcheng Zhu, Dongliang Li, Tianfei Zheng, Wen Cai, Jianghua Li, Baoyu Zhang, Beibei Zhu, Juan Zhang, Guocheng Du (2021). Bioaugmentation of Bacillus amyloliquefaciens–Bacillus kochii co-cultivation to improve sensory quality of flue-cured tobacco. Archives of Microbiology.DOI
Xinzhu Mao, Ziyang Huang, Guoyun Sun, Hongzhi Zhang, Wei Ping Lu, Yanfeng Liu, Xueqin Lv, Guocheng Du, Jianghua Li, Long Liu (2021). High level production of diacetylchitobiose deacetylase by refactoring genetic elements and cellular metabolism. Bioresource Technology.DOI
Bohan Zhang, Xinrui Zhao, Ziwei Wang, Haoze Wang, Jingwen Zhou, Guocheng Du, Jian Chen, Jianghua Li (2021). Efficient Secretory Expression and Purification of Food-Grade Porcine Myoglobin in Komagataella phaffii. Journal of Agricultural and Food Chemistry.DOI
Ke Liu, Haoran Yu, Guoyun Sun, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu (2021). Semi-rational design of L-amino acid deaminase for production of pyruvate and d-alanine by Escherichia coli whole-cell biocatalyst. Amino Acids.DOI
Yanting Cao, Rongzhen Tian, Xueqin Lv, Jianghua Li, Long Liu, Guocheng Du, Jian Chen, Yanfeng Liu (2021). Inducible Population Quality Control of Engineered Bacillus subtilis for Improved N-Acetylneuraminic Acid Biosynthesis. ACS Synthetic Biology.DOI
Guoqiang Zhang, Shujie Ma, Xiao Liu, Xinxin Yin, Song Liu, Jingwen Zhou, Guocheng Du (2021). Protein-glutaminase: Research progress and prospect in food manufacturing. Food Bioscience.DOI
Muhammad Iftikhar Hussain, Xiaolong Zhang, Xueqin Lv, Samra Basharat, Umar Shahbaz, Jianghua Li, Guocheng Du, Long Liu, Yanfeng Liu (2021). Enzymatic production of N-acetylneuraminic acid: advances and perspectives. Systems Microbiology and Biomanufacturing.DOI
Ruirui Xu, Yang Wang, Hao Huang, Xuerong Jin, Jianghua Li, Guocheng Du, Zhen Kang (2021). Closed-Loop System Driven by ADP Phosphorylation from Pyrophosphate Affords Equimolar Transformation of ATP to 3′-Phosphoadenosine-5′-phosphosulfate. ACS Catalysis.DOI
Deng Chen, Xueqin Lv, Jianghua Li, Hongzhi Zhang, Yanfeng Liu, Guocheng Du, Rodrigo Ledesma‐Amaro, Long Liu (2021). Synergistic improvement of N-acetylglucosamine production by engineering transcription factors and balancing redox cofactors. Metabolic Engineering.DOI
Zheng Peng, Peng Xu, Yang Song, Guocheng Du, Juan Zhang, Jian Chen (2021). Cysteine-Mediated Cyclic Metabolism Drives the Microbial Degradation of Keratin. ACS Sustainable Chemistry & Engineering.DOI
Fei Yu, Xinrui Zhao, Ziwei Wang, Luyao Liu, Lingfeng Yi, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du (2021). Recent Advances in the Physicochemical Properties and Biotechnological Application of Vitreoscilla Hemoglobin. Microorganisms.DOI
Shixiu Cui, Xueqin Lv, Xianhao Xu, Taichi Chen, Hongzhi Zhang, Yanfeng Liu, Jianghua Li, Guocheng Du, Rodrigo Ledesma‐Amaro, Long Liu (2021). Multilayer Genetic Circuits for Dynamic Regulation of Metabolic Pathways. ACS Synthetic Biology.DOI
Xuan Zhou, Mengyue Gong, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu (2021). Metabolic engineering for the synthesis of steviol glycosides: current status and future prospects. Applied Microbiology and Biotechnology.DOI
Xinxin Yin, Guoqiang Zhang, Jingwen Zhou, Jianghua Li, Guocheng Du (2021). Combinatorial engineering for efficient production of protein-glutaminase in Bacillus subtilis. Enzyme and Microbial Technology.DOI
Guoqiang Zhang, Yukun Chen, Qinghua Li, Jingwen Zhou, Jianghua Li, Guocheng Du (2021). Growth-coupled evolution and high-throughput screening assisted rapid enhancement for amylase-producing Bacillus licheniformis. Bioresource Technology.DOI
Sai Jin, Fuxin Sun, Zhijie Hu, Long Liu, Jianghua Li, Guocheng Du, Youran Li, Guiyang Shi, Jian Chen (2021). Improving Aspergillus niger seed preparation and citric acid production by morphology controlling-based semicontinuous cultivation. Biochemical Engineering Journal.DOI
Quanwei Zhang, Yaokang Wu, Mengyue Gong, Hongzhi Zhang, Yanfeng Liu, Xueqin Lv, Jianghua Li, Guocheng Du, Long Liu (2021). Production of proteins and commodity chemicals using engineered Bacillus subtilis platform strain. Essays in Biochemistry.DOI
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Changjiang Lyu, Lili Yao, Qi Zhu, Jiaqi Mei, Yucheng Cao, Sheng Chuan Hu, Weirui Zhao, Jun Huang, Lehe Mei, Shan‐Jing Yao, Guocheng Du (2021). Reconstruction of the glutamate decarboxylase system in Lactococcus lactis for biosynthesis of food-grade γ-aminobutyric acid. Applied Microbiology and Biotechnology.DOI
Ziyang Huang, Xinzhu Mao, Xueqin Lv, Guoyun Sun, Hongzhi Zhang, Wei Ping Lu, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu (2021). Engineering diacetylchitobiose deacetylase from Pyrococcus horikoshii towards an efficient glucosamine production. Bioresource Technology.DOI
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Panhong Yuan, Guoyun Sun, Shixiu Cui, Yaokang Wu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu (2021). Engineering a ComA Quorum-Sensing circuit to dynamically control the production of Menaquinone-4 in Bacillus subtilis. Enzyme and Microbial Technology.DOI
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Xiaoqiang Yin, Yangyang Li, Jingwen Zhou, Shengqi Rao, Guocheng Du, Jian Chen, Song Liu (2021). Enhanced Production of Transglutaminase in Streptomyces mobaraensis through Random Mutagenesis and Site-Directed Genetic Modification. Journal of Agricultural and Food Chemistry.DOI
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Shufang Tian, Xiaolin Liang, Jian Chen, Weizhu Zeng, Jingwen Zhou, Guocheng Du (2020). Enhancement of 2-phenylethanol production by a wild-type Wickerhamomyces anomalus strain isolated from rice wine. Bioresource Technology.DOI
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Rongzhen Tian, Yanfeng Liu, Yanting Cao, Zhongjie Zhang, Jianghua Li, Long Liu, Guocheng Du, Jian Chen (2020). Titrating bacterial growth and chemical biosynthesis for efficient N-acetylglucosamine and N-acetylneuraminic acid bioproduction. Nature Communications.DOI
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Tengfei Niu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Rodrigo Ledesma‐Amaro, Long Liu (2020). The elucidation of phosphosugar stress response in Bacillus subtilis guides strain engineering for high N‐acetylglucosamine production. Biotechnology and Bioengineering.DOI
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Ke Liu, Mengyue Gong, Xueqin Lv, Jianghua Li, Guocheng Du, Long Liu (2020). Biotransformation and chiral resolution of d , l ‐alanine into pyruvate and d ‐alanine with a whole‐cell biocatalyst expressing l ‐amino acid deaminase. Biotechnology and Applied Biochemistry.DOI
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Taichi Chen, Hongzhi Xia, Shixiu Cui, Xueqin Lv, Xueliang Li, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu (2020). Combinatorial Methylerythritol Phosphate Pathway Engineering and Process Optimization for Increased Menaquinone-7 Synthesis in Bacillus subtilis. Journal of Microbiology and Biotechnology.DOI
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Zhen Fang, Chong Sha, Zheng Peng, Juan Zhang, Guocheng Du (2018). Protein engineering to enhance keratinolytic protease activity and excretion in Escherichia coli and its scale-up fermentation for high extracellular yield. Enzyme and Microbial Technology.DOI
Shuo Wang, Xinxin Ma, Yuying Wang, Guocheng Du, Joo‐Hwa Tay, Ji Li (2018). Piggery wastewater treatment by aerobic granular sludge: Granulation process and antibiotics and antibiotic-resistant bacteria removal and transport. Bioresource Technology.DOI
Shuo Wang, Kai Qian, Yin Zhu, Xuesong Yi, Guangsheng Zhang, Guocheng Du, Joo‐Hwa Tay, Ji Li (2018). Reactivation and pilot-scale application of long-term storage denitrification biofilm based on flow cytometry. Water Research.DOI
Yang Mo Gu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Rodrigo Ledesma‐Amaro, Long Liu (2018). Synthetic redesign of central carbon and redox metabolism for high yield production of N-acetylglucosamine in Bacillus subtilis. Metabolic Engineering.DOI
Yue Min Feng, Song Liu, Yun Jiao, Yunlong Wang, Miao Wang, Guocheng Du (2018). Gene cloning and expression of the l-asparaginase from Bacillus cereus BDRD-ST26 in Bacillus subtilis WB600. Journal of Bioscience and Bioengineering.DOI
Deng Chen, Xueqin Lv, Jianghua Li, Yanfeng Liu, Guocheng Du, Rodrigo Ledesma‐Amaro, Long Liu (2018). Synthetic repetitive extragenic palindromic (REP) sequence as an efficient mRNA stabilizer for protein production and metabolic engineering in prokaryotic cells. Biotechnology and Bioengineering.DOI
Zhengming Zhu, Xiaomei Ji, Zhimeng Wu, Juan Zhang, Guocheng Du (2018). Improved acid-stress tolerance of Lactococcus lactis NZ9000 and Escherichia coli BL21 by overexpression of the anti-acid component recT. Journal of Industrial Microbiology & Biotechnology.DOI
Meixi Ling, Jianghua Li, Guocheng Du, Long Liu (2018). Metabolic engineering for the production of chitooligosaccharides: advances and perspectives. Emerging Topics in Life Sciences.DOI
Sen Yang, Yang Wang, Chaobao Wei, Qingtao Liu, Xuerong Jin, Guocheng Du, Jian Chen, Zhen Kang (2018). A new sRNA‐mediated posttranscriptional regulation system for Bacillus subtilis. Biotechnology and Bioengineering.DOI
Fei Ge, Longbao Zhu, Liangjun Yang, Wanzhen Li, Shenghua Wei, Yugui Tao, Guocheng Du (2018). The Soluble and Particulate Form of Alginates Positively Regulate Immune Response. PubMed.DOI
Haibo Yuan, Yanfeng Liu, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Zhongping Shi, Jian Chen, Long Liu (2018). Cover Image, Volume 115, Number 9, September 2018. Biotechnology and Bioengineering.DOI
Yaokang Wu, Taichi Chen, Yanfeng Liu, Xueqin Lv, Jianghua Li, Guocheng Du, Rodrigo Ledesma‐Amaro, Long Liu (2018). CRISPRi allows optimal temporal control of N-acetylglucosamine bioproduction by a dynamic coordination of glucose and xylose metabolism in Bacillus subtilis. Metabolic Engineering.DOI
Tengfei Niu, Yanfeng Liu, Jianghua Li, Mattheos A. G. Koffas, Guocheng Du, Hal S. Alper, Long Liu (2018). Engineering a Glucosamine-6-phosphate Responsive glmS Ribozyme Switch Enables Dynamic Control of Metabolic Flux in Bacillus subtilis for Overproduction of N-Acetylglucosamine. ACS Synthetic Biology.DOI
Wenlong Ma, Yanfeng Liu, Yue Wang, Xueqin Lv, Jianghua Li, Guocheng Du, Long Liu (2018). Combinatorial Fine-Tuning of GNA1 and GlmS Expression by 5’-Terminus Fusion Engineering Leads to Overproduction of N-Acetylglucosamine inBacillus subtilis. Biotechnology Journal.DOI
Jingjing Liu, Jianghua Li, Yanfeng Liu, Hyun‐Dong Shin, Rodrigo Ledesma‐Amaro, Guocheng Du, Jian Chen, Long Liu (2018). Synergistic Rewiring of Carbon Metabolism and Redox Metabolism in Cytoplasm and Mitochondria of Aspergillus oryzae for Increased l -Malate Production. ACS Synthetic Biology.DOI
Xiuting Wang, Ying Hou, Long Liu, Jianghua Li, Guocheng Du, Jian Chen, Miao Wang (2018). A new approach for efficient synthesis of phenyllactic acid from L-phenylalanine: Pathway design and cofactor engineering. Journal of Food Biochemistry.DOI
Shuo Wang, Jianzheng Li, Guochen Zheng, Guocheng Du, Ji Li (2018). Bioaugmentation with Mixed Hydrogen-Producing Acetogen Cultures Enhances Methane Production in Molasses Wastewater Treatment. Archaea.DOI
Chunhui Ren, Juan Zhang, Guocheng Du, Jian Chen (2018). [Enhancing thermal stability of glucose oxidase by fusing amphiphilic short peptide]. PubMed.DOI
Yongkun Lv, Xiaozhong Cheng, Di Wu, Guocheng Du, Jingwen Zhou, Jian Chen (2018). Improving bioconversion of eugenol to coniferyl alcohol by in situ eliminating harmful H2O2. Bioresource Technology.DOI
Panpan Wang, Weizhu Zeng, Sha Xu, Guocheng Du, Jingwen Zhou, Jian Chen (2018). Current challenges facing one-step production of l-ascorbic acid. Biotechnology Advances.DOI
Weizhu Zeng, Sha Xu, Guocheng Du, Song Liu, Jingwen Zhou (2018). Separation and purification of α-ketoglutarate and pyruvate from the fermentation broth of Yarrowia lipolytica. Bioprocess and Biosystems Engineering.DOI
Weixin Zhao, Li Liu, Guocheng Du, Song Liu (2018). A multifunctional tag with the ability to benefit the expression, purification, thermostability and activity of recombinant proteins. Journal of Biotechnology.DOI
Shuo Wang, Cong Ma, Yin Zhu, Yangkun Yang, Guocheng Du, Ji Li (2018). Deep dewatering process of sludge by chemical conditioning and its potential influence on wastewater treatment plants. Environmental Science and Pollution Research.DOI
Xiaolong Zhang, Yanfeng Liu, Long Liu, Miao Wang, Jianghua Li, Guocheng Du, Jian Chen (2018). Modular pathway engineering of key carbon‐precursor supply‐pathways for improved N ‐acetylneuraminic acid production in Bacillus subtilis. Biotechnology and Bioengineering.DOI
Weiping Zhang, Yan Cheng, Yudong Li, Guocheng Du, Guangfa Xie, Huijun Zou, Jingwen Zhou, Jian Chen (2018). Adaptive Evolution Relieves Nitrogen Catabolite Repression and Decreases Urea Accumulation in Cultures of the Chinese Rice Wine Yeast Strain Saccharomyces cerevisiae XZ-11. Journal of Agricultural and Food Chemistry.DOI
Yang Mo Gu, Xianhao Xu, Yaokang Wu, Tengfei Niu, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu (2018). Advances and prospects of Bacillus subtilis cellular factories: From rational design to industrial applications. Metabolic Engineering.DOI
Yue Min Feng, Song Liu, Yun Jiao, Yunlong Wang, Miao Wang, Guocheng Du, Jian Chen (2018). Improvement of l -asparaginase thermal stability by regulating enzyme kinetic and thermodynamic states. Process Biochemistry.DOI
Haibo Yuan, Yanfeng Liu, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Zhongping Shi, Jian Chen, Long Liu (2018). Combinatorial synthetic pathway fine‐tuning and comparative transcriptomics for metabolic engineering of Raoultella ornithinolytica BF60 to efficiently synthesize 2,5‐furandicarboxylic acid. Biotechnology and Bioengineering.DOI
Yingying Zhang, Bin Tang, Guocheng Du (2018). Transcriptional regulator XYR1 activates the expression of cellobiose synthase to promote the production of cellulase from glucose. Biotechnology Letters.DOI
Zhen Kang, Zhengxiong Zhou, Yang Wang, Hao Huang, Guocheng Du, Jian Chen (2018). Bio-Based Strategies for Producing Glycosaminoglycans and Their Oligosaccharides. Trends in biotechnology.DOI
Zhengming Zhu, Juan Zhang, Xiaomei Ji, Zhen Fang, Zhimeng Wu, Jian Chen, Guocheng Du (2018). Evolutionary engineering of industrial microorganisms-strategies and applications. Applied Microbiology and Biotechnology.DOI
Longbao Zhu, Fei Ge, Wanzhen Li, Ping Song, Hongjin Tang, Yugui Tao, Yi Liu, Guocheng Du (2018). One step synthesis of unnatural β-arylalanines using mutant phenylalanine aminomutase from Taxus chinensis with high β-regioselectivity. Enzyme and Microbial Technology.DOI
Zhengxiong Zhou, Qing Li, Hao Huang, Hao Wang, Yang Wang, Guocheng Du, Jian Chen, Zhen Kang (2018). A microbial–enzymatic strategy for producing chondroitin sulfate glycosaminoglycans. Biotechnology and Bioengineering.DOI
Fang Fang, Jiran Zhang, Jingwen Zhou, Zhaohui Sunny Zhou, Tieqiao Li, Liling Lu, Weizhu Zeng, Guocheng Du, Jian Chen (2018). Accumulation of Citrulline by Microbial Arginine Metabolism during Alcoholic Fermentation of Soy Sauce. Journal of Agricultural and Food Chemistry.DOI
Fang Fang, Yuying Qiu, Guocheng Du, Jian Chen (2018). Evaluation of ethyl carbamate formation in Luzhou-flavor spirit during distillation and storage processes. Food Bioscience.DOI
Fei Ge, Longbao Zhu, Anna Aang, Ping Song, Wanzhen Li, Yugui Tao, Guocheng Du (2018). Recent advances in enhanced enzyme activity, thermostability and secretion by N-glycosylation regulation in yeast. Biotechnology Letters.DOI
Weiping Zhang, Guocheng Du, Jingwen Zhou, Jian Chen (2018). Regulation of Sensing, Transportation, and Catabolism of Nitrogen Sources in Saccharomyces cerevisiae. Microbiology and Molecular Biology Reviews.DOI
Weiping Zhang, Yudong Li, Yiwang Chen, Sha Xu, Guocheng Du, Huidong Shi, Jingwen Zhou, Jian Chen (2018). Complete genome sequence and analysis of the industrial Saccharomyces cerevisiae strain N85 used in Chinese rice wine production. DNA Research.DOI
Chen Deng, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Jian Chen, Long Liu (2017). Efficient expression of cyclodextrin glycosyltransferase from Geobacillus stearothermophilus in Escherichia coli by promoter engineering and downstream box evolution. Journal of Biotechnology.DOI
Jingjing Liu, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Jian Chen, Long Liu (2017). Biological production of l-malate: recent advances and future prospects. World Journal of Microbiology and Biotechnology.DOI
Wenlong Ma, Yanfeng Liu, Hyun‐Dong Shin, Jianghua Li, Jian Chen, Guocheng Du, Long Liu (2017). Metabolic engineering of carbon overflow metabolism of Bacillus subtilis for improved N-acetyl-glucosamine production. Bioresource Technology.DOI
Sen Yang, Qingtao Liu, Yunfeng Zhang, Guocheng Du, Jian Chen, Zhen Kang (2017). Construction and Characterization of Broad-Spectrum Promoters for Synthetic Biology. ACS Synthetic Biology.DOI
Ningzi Guan, Bin Du, Jianghua Li, Hyun‐Dong Shin, Rachel R. Chen, Guocheng Du, Jian Chen, Long Liu (2017). Comparative genomics and transcriptomics analysis‐guided metabolic engineering of Propionibacterium acidipropionici for improved propionic acid production. Biotechnology and Bioengineering.DOI
Zhen Kang, Wenwen Ding, Gong Xu, Qingtao Liu, Guocheng Du, Jian Chen (2017). Recent advances in production of 5-aminolevulinic acid using biological strategies. World Journal of Microbiology and Biotechnology.DOI
Zhengshan Luo, Song Liu, Guocheng Du, Sha Xu, Jingwen Zhou, Jian Chen (2017). Enhanced pyruvate production in Candida glabrata by carrier engineering. Biotechnology and Bioengineering.DOI
Yongkun Lv, Song Gao, Sha Xu, Guocheng Du, Jingwen Zhou, Jian Chen (2017). Spatial organization of silybin biosynthesis in milk thistle [Silybum marianum (L.) Gaertn]. The Plant Journal.DOI
Jingjing Liu, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Jian Chen, Long Liu (2017). Metabolic engineering of Aspergillus oryzae for efficient production of l -malate directly from corn starch. Journal of Biotechnology.DOI
Fei Ge, Qisen Ma, Longbao Zhu, Jingjing Zhan, Siwen Xiang, Wanzhen Li, Ping Song, Yugui Tao, Guocheng Du (2017). Tunable adsorption behavior of silica materials in the removal of dense non-aqueous phase liquids. Journal of Materials Science.DOI
Zhen Fang, Yang‐Chun Yong, Juan Zhang, Guocheng Du, Jian Chen (2017). Keratinolytic protease: a green biocatalyst for leather industry. Applied Microbiology and Biotechnology.DOI
Meixi Ling, Yanfeng Liu, Jianghua Li, Hyun‐Dong Shin, Jian Chen, Guocheng Du, Long Liu (2017). Combinatorial promoter engineering of glucokinase and phosphoglucoisomerase for improved N-acetylglucosamine production in Bacillus subtilis. Bioresource Technology.DOI
Haibo Yuan, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Jian Chen, Zhongping Shi, Long Liu (2017). Improved production of 2,5-furandicarboxylic acid by overexpression of 5-hydroxymethylfurfural oxidase and 5-hydroxymethylfurfural/furfural oxidoreductase in Raoultella ornithinolytica BF60. Bioresource Technology.DOI
Yingying Zhang, Bin Tang, Guocheng Du (2017). Self-induction system for cellulase production by cellobiose produced from glucose in Rhizopus stolonifer. Scientific Reports.DOI
Zhen Fang, Juan Zhang, Guocheng Du, Jian Chen (2017). Rational protein engineering approaches to further improve the keratinolytic activity and thermostability of engineered keratinase KerSMD. Biochemical Engineering Journal.DOI
Yunfeng Zhang, Hao Huang, Xinhui Yao, Guocheng Du, Jian Chen, Zhen Kang (2017). High-yield secretory production of stable, active trypsin through engineering of the N-terminal peptide and self-degradation sites in Pichia pastoris. Bioresource Technology.DOI
Jean Paul Sinumvayo, Sen Yang, Jian Chen, Guocheng Du, Zhen Kang (2017). [Engineering and characterization of new intrinsic transcriptional terminators in Bacillus subtilis 168]. PubMed.DOI
Yang Gu, Jieying Deng, Yanfeng Liu, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Jian Chen, Long Liu (2017). Rewiring the Glucose Transportation and Central Metabolic Pathways for Overproduction of N‐Acetylglucosamine in Bacillus subtilis. Biotechnology Journal.DOI
Taher Khakpour Moghaddam, Juan Zhang, Guocheng Du (2017). Pre-cold stress increases acid stress resistance and induces amino acid homeostasis in Lactococcus lactis NZ9000. Tropical Journal of Pharmaceutical Research.DOI
Yang Song, Jianghua Li, Hyun‐Dong Shin, Long Liu, Guocheng Du, Jian Chen (2017). Tuning the transcription and translation of L-amino acid deaminase in Escherichia coli improves α-ketoisocaproate production from L-leucine. PLoS ONE.DOI
Juan Zhang, Yanqiu Cai, Guocheng Du, Jian Chen, Miao Wang, Zhen Kang (2017). Evaluation and application of constitutive promoters for cutinase production by Saccharomyces cerevisiae. The Journal of Microbiology.DOI
Linpei Zhang, Hao Wang, Zhengxiong Zhou, Guocheng Du, Jian Chen, Zhen Kang (2017). [Optimization of heparosan synthetic pathway in Bacillus subtilis 168]. PubMed.DOI
Qingtao Liu, Yuqi Chen, Minglai Yuan, Guocheng Du, Jian Chen, Zhen Kang (2017). A Bacillus paralicheniformis Iron-Containing Urease Reduces Urea Concentrations in Rice Wine. Applied and Environmental Microbiology.DOI
Jingjing Liu, Zhipeng Xie, Hyun‐Dong Shin, Jianghua Li, Guocheng Du, Jian Chen, Long Liu (2017). Rewiring the reductive tricarboxylic acid pathway and L-malate transport pathway of Aspergillus oryzae for overproduction of L-malate. Journal of Biotechnology.DOI
Ying Hou, Gazi S. Hossain, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Jian Chen, Long Liu (2017). Metabolic engineering of cofactor flavin adenine dinucleotide (FAD) synthesis and regeneration in Escherichia coli for production of α‐keto acids. Biotechnology and Bioengineering.DOI
Yongkun Lv, Xiaozhong Cheng, Guocheng Du, Jingwen Zhou, Jian Chen (2017). Engineering of an H2O2 auto‐scavenging in vivo cascade for pinoresinol production. Biotechnology and Bioengineering.DOI
Jingjing Liu, Jianghua Li, Hyun‐Dong Shin, Long Liu, Guocheng Du, Jian Chen (2017). Protein and metabolic engineering for the production of organic acids. Bioresource Technology.DOI
Ningzi Guan, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Jian Chen, Long Liu (2017). Microbial response to environmental stresses: from fundamental mechanisms to practical applications. Applied Microbiology and Biotechnology.DOI
Wenwen Ding, Huanjiao Weng, Peng Kang Jin, Guocheng Du, Jian Chen, Zhen Kang (2017). Scarless assembly of unphosphorylated DNA fragments with a simplified DATEL method. Bioengineered.DOI
Wenwen Ding, Huanjiao Weng, Guocheng Du, Jian Chen, Zhen Kang (2017). 5-Aminolevulinic acid production from inexpensive glucose by engineering the C4 pathway in Escherichia coli. Journal of Industrial Microbiology & Biotechnology.DOI
Yingyiing Zhang, Bin Hong Tang, Guocheng Du (2017). Production of Cellulases by Rhizopus stolonifer from Glucose-Containing Media Based on the Regulation of Transcriptional Regulator CRE. Journal of Microbiology and Biotechnology.DOI
Zhengshan Luo, Song Liu, Guocheng Du, Jingwen Zhou, Jian Chen (2017). Identification of a polysaccharide produced by the pyruvate overproducer Candida glabrata CCTCC M202019. Applied Microbiology and Biotechnology.DOI
Shenghu Zhou, Renpeng Ding, Jian Chen, Guocheng Du, Huazhong Li, Jingwen Zhou (2017). Obtaining a Panel of Cascade Promoter-5′-UTR Complexes in Escherichia coli. ACS Synthetic Biology.DOI
Taher Khakpour Moghaddam, Juan Zhang, Guocheng Du (2017). UvrA expression of Lactococcus lactis NZ9000 improve multiple stresses tolerance and fermentation of lactic acid against salt stress. Journal of Food Science and Technology.DOI
Sen Yang, Guocheng Du, Jian Chen, Zhen Kang (2017). Characterization and application of endogenous phase-dependent promoters in Bacillus subtilis. Applied Microbiology and Biotechnology.DOI
Peng Zhang, Guocheng Du, Huijun Zou, Guangfa Xie, Jian Chen, Zhongping Shi, Jingwen Zhou (2017). Mutant Potential Ubiquitination Sites in Dur3p Enhance the Urea and Ethyl Carbamate Reduction in a Model Rice Wine System. Journal of Agricultural and Food Chemistry.DOI
Zhengshan Luo, Weizhu Zeng, Guocheng Du, Song Liu, Fang Fang, Jingwen Zhou, Jian Chen (2017). A high-throughput screening procedure for enhancing pyruvate production in Candida glabrata by random mutagenesis. Bioprocess and Biosystems Engineering.DOI
Xian Yin, Hyun‐Dong Shin, Jianghua Li, Guocheng Du, Long Liu, Jian Chen (2017). Comparative genomics and transcriptome analysis of Aspergillus niger and metabolic engineering for citrate production. Scientific Reports.DOI
Xian Yin, Hyun‐Dong Shin, Jianghua Li, Guocheng Du, Long Liu, Jian Chen (2017). P gas , a Low-pH-Induced Promoter, as a Tool for Dynamic Control of Gene Expression for Metabolic Engineering of Aspergillus niger. Applied and Environmental Microbiology.DOI
Shenghu Zhou, Guocheng Du, Zhen Kang, Jianghua Li, Jian Chen, Huazhong Li, Jingwen Zhou (2017). The application of powerful promoters to enhance gene expression in industrial microorganisms. World Journal of Microbiology and Biotechnology.DOI
Ruoxi Li, Hossain Gazi Sakir, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Jian Chen, Long Liu (2017). Rational molecular engineering of l -amino acid deaminase for production of α-ketoisovaleric acid from l -valine by Escherichia coli. RSC Advances.DOI
Na Zhang, Jiang-Hua Li, P. Jin, Guo-Cheng Du, Jian Chen, Zhen Kang (2016). Enhanced Expression of Hyalurondiase in Pichia pastoris by Two-Stage Temperature Induction Strategy.
Zhen Kang, Hao Huang, Yunfeng Zhang, Guocheng Du, Jian Chen (2016). Recent advances of molecular toolbox construction expand Pichia pastoris in synthetic biology applications. World Journal of Microbiology and Biotechnology.DOI
Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Long Liu (2016). Metabolic engineering of Bacillus subtilis fueled by systems biology: Recent advances and future directions. Biotechnology Advances.DOI
Ying Hou, Gazi Sakir Hossain, Jianghua Li, Hyun‐Dong Shin, Long Liu, Guocheng Du, Jian Chen (2016). Two-Step Production of Phenylpyruvic Acid from L-Phenylalanine by Growing and Resting Cells of Engineered Escherichia coli: Process Optimization and Kinetics Modeling. PLoS ONE.DOI
Yue Min Feng, Song Liu, Yun Jiao, Hui Gao, Miao Wang, Guocheng Du, Jian Chen (2016). Enhanced extracellular production of L-asparaginase from Bacillus subtilis 168 by B. subtilis WB600 through a combined strategy. Applied Microbiology and Biotechnology.DOI
Song Liu, Miao Wang, Guocheng Du, Jian Chen (2016). Improving the active expression of transglutaminase in Streptomyces lividans by promoter engineering and codon optimization. BMC Biotechnology.DOI
Xinyao Lu, Guangsheng Wang, Yue Feng, Song Liu, Xiaoman Zhou, Guocheng Du, Jian Chen (2016). The N-Terminal α-Helix Domain of Pseudomonas aeruginosa Lipoxygenase Is Required for Its Soluble Expression in Escherichia coli but Not for Catalysis. Journal of Microbiology and Biotechnology.DOI
Gazi Sakir Hossain, Haibo Yuan, Jianghua Li, Hyun‐Dong Shin, Miao Wang, Guocheng Du, Jian Chen, Long Liu (2016). Metabolic Engineering of Raoultella ornithinolytica BF60 for Production of 2,5-Furandicarboxylic Acid from 5-Hydroxymethylfurfural. Applied and Environmental Microbiology.DOI
Weizhu Zeng, Fang Fang, Song Liu, Guocheng Du, Jian Chen, Jingwen Zhou (2016). Comparative genomics analysis of a series of Yarrowia lipolytica WSH-Z06 mutants with varied capacity for α-ketoglutarate production. Journal of Biotechnology.DOI
Xiaohui Liu, Fang Fang, Xiaole Xia, Guocheng Du, Jian Chen (2016). [Stability enhancement of urethanase from Lysinibacillus fusiformis by site-directed mutagenesis]. PubMed.DOI
Peng Zhang, Guocheng Du, Huijun Zou, Guangfa Xie, Jian Chen, Zhongping Shi, Jingwen Zhou (2016). Genome-wide mapping of nucleosome positions in Saccharomyces cerevisiae in response to different nitrogen conditions. Scientific Reports.DOI
Wei Wang, Yawen Liu, Zhen Sun, Guocheng Du, Xianzhen Li (2016). Hop resistance and beer-spoilage features of foodborne Bacillus cereus newly isolated from filtration-sterilized draft beer. Annals of Microbiology.DOI
Linpei Zhang, Hao Huang, Hao Wang, Jian Chen, Guocheng Du, Zhen Kang (2016). Rapid evolution of hyaluronan synthase to improve hyaluronan production and molecular mass in Bacillus subtilis. Biotechnology Letters.DOI
Huizhi Li, Zhen Kang, Jianghua Li, Jingwen Zhou, Guocheng Du (2016). [Mutagenesis of Methylobacterium extorquens AM1 for increasing pyrroloquinoline quinone production by atmospheric and room temperature plasma]. PubMed.DOI
Yang Song, Jianghua Li, Hyun‐Dong Shin, Long Liu, Guocheng Du, Jian Chen (2016). Biotechnological production of alpha-keto acids: Current status and perspectives. Bioresource Technology.DOI
Shenghu Zhou, Peiran Liu, Jian Chen, Guocheng Du, Huazhong Li, Jingwen Zhou (2016). Characterization of mutants of a tyrosine ammonia-lyase from Rhodotorula glutinis. Applied Microbiology and Biotechnology.DOI
Guocheng Du (2016). Polyvinyl alcohol (PVA)-degrading enzyme: Structure analysis, heterologous overexpression, and applications. New Biotechnology.DOI
Yanfeng Liu, Hannes Link, Long Liu, Guocheng Du, Jian Chen, Uwe Sauer (2016). A dynamic pathway analysis approach reveals a limiting futile cycle in N-acetylglucosamine overproducing Bacillus subtilis. Nature Communications.DOI
Jiran Zhang, Guocheng Du, Jian Chen, Fang Fang (2016). Characterization of a Bacillus amyloliquefaciens strain for reduction of citrulline accumulation during soy sauce fermentation. Biotechnology Letters.DOI
Zhen Fang, Juan Zhang, Guocheng Du, Jian Chen (2016). Improved catalytic efficiency, thermophilicity, anti-salt and detergent tolerance of keratinase KerSMD by partially truncation of PPC domain. Scientific Reports.DOI
Peng Kang Jin, Wenwen Ding, Guocheng Du, Jian Chen, Zhen Kang (2016). DATEL: A Scarless and Sequence-Independent DNA Assembly Method Using Thermostable Exonucleases and Ligase. ACS Synthetic Biology.DOI
Ye Liu, Gong Xu, Cui Wang, Guocheng Du, Jian Chen, Zhen Kang (2016). Production of glucaric acid from myo-inositol in engineered Pichia pastoris. Enzyme and Microbial Technology.DOI
Yunfeng Zhang, Zhenmin Ling, Guocheng Du, Jian Chen, Zhen Kang (2016). Improved Production of Active Streptomyces griseus Trypsin with a Novel Auto-Catalyzed Strategy. Scientific Reports.DOI
Xinrui Zhao, Huijun Zou, Jian Chen, Guocheng Du, Jingwen Zhou (2016). The modification of Gat1p in nitrogen catabolite repression to enhance non-preferred nitrogen utilization in Saccharomyces cerevisiae. Scientific Reports.DOI
Fang Fang, Tingting Feng, Guocheng Du, Jian Chen (2016). Evaluation of the impact on food safety of aLactobacillus coryniformisstrain from pickled vegetables with degradation activity against nitrite and other undesirable compounds. Food Additives & Contaminants Part A.DOI
Peng Zhang, Guocheng Du, Huijun Zou, Jian Chen, Guangfa Xie, Zhongping Shi, Jingwen Zhou (2016). Effects of three permeases on arginine utilization in Saccharomyces cerevisiae. Scientific Reports.DOI
Peng Kang Jin, Zhen Kang, Panhong Yuan, Guocheng Du, Jian Chen (2016). Production of specific-molecular-weight hyaluronan by metabolically engineered Bacillus subtilis 168. Metabolic Engineering.DOI
Long Liu, Ningzi Guan, Zhu Gexin, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Jian Chen (2016). Pathway engineering of Propionibacterium jensenii for improved production of propionic acid. Scientific Reports.DOI
Gazi Sakir Hossain, Hyun‐Dong Shin, Jianghua Li, Miao Wang, Guocheng Du, Jian Chen, Long Liu (2016). Metabolic engineering for amino-, oligo-, and polysugar production in microbes. Applied Microbiology and Biotechnology.DOI
Peng Kang Jin, Zhen Kang, Junli Zhang, Linpei Zhang, Guocheng Du, Jian Chen (2016). Combinatorial Evolution of Enzymes and Synthetic Pathways Using One-Step PCR. ACS Synthetic Biology.DOI
Gazi Sakir Hossain, Hyun‐Dong Shin, Jianghua Li, Guocheng Du, Jian Chen, Long Liu (2016). Transporter engineering and enzyme evolution for pyruvate production from d / l -alanine with a whole-cell biocatalyst expressing l -amino acid deaminase from Proteus mirabilis. RSC Advances.DOI
Gazi Sakir Hossain, Hyun‐Dong Shin, Jianghua Li, Miao Wang, Guocheng Du, Long Liu, Jian Chen (2016). Integrating error-prone PCR and DNA shuffling as an effective molecular evolution strategy for the production of α-ketoglutaric acid by l -amino acid deaminase. RSC Advances.DOI
Zhen Kang, Jian Chen, P. Jin, Guo-Cheng Du, Jun-Li Zhang (2015). A method based on the evolutionary pathway synthesizing single-stranded dna library.
Peng Kang Jin, Linpei Zhang, Panhong Yuan, Zhen Kang, Guocheng Du, Jian Chen (2015). Efficient biosynthesis of polysaccharides chondroitin and heparosan by metabolically engineered Bacillus subtilis. Carbohydrate Polymers.DOI
Jie Bi, Song Liu, Guocheng Du, Jian Chen (2015). Bile salt tolerance of Lactococcus lactis is enhanced by expression of bile salt hydrolase thereby producing less bile acid in the cells. Biotechnology Letters.DOI
Juan Zhang, Qian Liu, Wei Chen, Guocheng Du, Jian Chen (2015). Short communication: Protection of lyophilized milk starter Lactobacillus casei Zhang by glutathione. Journal of Dairy Science.DOI
Long Liu, Ningzi Guan, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Jian Chen (2015). Development of GRAS strains for nutraceutical production using systems and synthetic biology approaches: advances and prospects. Critical Reviews in Biotechnology.DOI
Sen Yang, Zhen Kang, Wenlong Cao, Guocheng Du, Jian Chen (2015). Construction of a novel, stable, food-grade expression system by engineering the endogenous toxin-antitoxin system in Bacillus subtilis. Journal of Biotechnology.DOI
Ningzi Guan, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Jian Chen, Long Liu (2015). Metabolic engineering of acid resistance elements to improve acid resistance and propionic acid production of Propionibacterium jensenii. Biotechnology and Bioengineering.DOI
Junli Zhang, Zhen Kang, Wenwen Ding, Jian Chen, Guocheng Du (2015). Integrated Optimization of the In Vivo Heme Biosynthesis Pathway and the In Vitro Iron Concentration for 5-Aminolevulinate Production. Applied Biochemistry and Biotechnology.DOI
Zhen Fang, Juan Zhang, Baihong Liu, Guocheng Du, Jian Chen (2015). Enhancement of the catalytic efficiency and thermostability of S tenotrophomonas sp. keratinase KerSMD by domain exchange with KerSMF. Microbial Biotechnology.DOI
Ying Hou, Gazi Sakir Hossain, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Long Liu (2015). Combination of phenylpyruvic acid (PPA) pathway engineering and molecular engineering of l-amino acid deaminase improves PPA production with an Escherichia coli whole-cell biocatalyst. Applied Microbiology and Biotechnology.DOI
Hongwei Guo, Catherine Madzak, Guocheng Du, Jingwen Zhou (2015). Mutagenesis of conserved active site residues of dihydrolipoamide succinyltransferase enhances the accumulation of α-ketoglutarate in Yarrowia lipolytica. Applied Microbiology and Biotechnology.DOI
Xinrui Zhao, Huijun Zou, Guocheng Du, Jian Chen, Jingwen Zhou (2015). Effects of nitrogen catabolite repression-related amino acids on the flavour of rice wine. Journal of the Institute of Brewing.DOI
Junjun Wu, Guocheng Du, Jian Chen, Jingwen Zhou (2015). Enhancing flavonoid production by systematically tuning the central metabolic pathways based on a CRISPR interference system in Escherichia coli. Scientific Reports.DOI
Song Liu, Dan Wan, Miao Wang, Catherine Madzak, Guocheng Du, Jian Chen (2015). Overproduction of pro-transglutaminase from Streptomyces hygroscopicus in Yarrowia lipolytica and its biochemical characterization. BMC Biotechnology.DOI
Yang Song, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Long Liu, Jian Chen (2015). One-step biosynthesis of α-ketoisocaproate from l-leucine by an Escherichia coli whole-cell biocatalyst expressing an l-amino acid deaminase from Proteus vulgaris. Scientific Reports.DOI
Zixing Dong, Juan Zhang, Guocheng Du, Jian Chen, Huazhong Li, Byonghoon Lee (2015). Periplasmic Export of Bile Salt Hydrolase in Escherichia coli by the Twin-Arginine Signal Peptides. Applied Biochemistry and Biotechnology.DOI
Yingfang Ma, Haiquan Yang, Xianzhong Chen, Bo Sun, Guocheng Du, Zhemin Zhou, Jiangning Song, You Jun Fan, Wei Shen (2015). Significantly improving the yield of recombinant proteins in Bacillus subtilis by a novel powerful mutagenesis tool (ARTP): Alkaline α-amylase as a case study. Protein Expression and Purification.DOI
Ying Hou, Gazi Sakir Hossain, Jianghua Li, Hyun‐Dong Shin, Long Liu, Guocheng Du (2015). Production of phenylpyruvic acid from l-phenylalanine using an l-amino acid deaminase from Proteus mirabilis: comparison of enzymatic and whole-cell biotransformation approaches. Applied Microbiology and Biotechnology.DOI
Weizhu Zeng, Guocheng Du, Jian Chen, Jianghua Li, Jingwen Zhou (2015). A high-throughput screening procedure for enhancing α-ketoglutaric acid production in Yarrowia lipolytica by random mutagenesis. Process Biochemistry.DOI
Song Liu, Jun Dai, Zhen Kang, Jianghua Li, Jian Chen, Guocheng Du (2015). Production of novel NaN3-resistant creatine amidinohydrolase in recombinantEscherichia coli. Bioengineered.DOI
Panhong Yuan, Mengxian Lv, Peng Kang Jin, Miao Wang, Guocheng Du, Jian Chen, Zhen Kang (2015). Enzymatic production of specifically distributed hyaluronan oligosaccharides. Carbohydrate Polymers.DOI
Chengran Guan, Wenjing Cui, Xiaotian He, Xu Xiao Hu, Jun Yang Xu, Guocheng Du, Jian Chen, Zhemin Zhou (2015). Construction and development of a novel expression system of Streptomyces. Protein Expression and Purification.DOI
Xian Yin, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Long Liu, Jian Chen (2015). Metabolic engineering in the biotechnological production of organic acids in the tricarboxylic acid cycle of microorganisms: Advances and prospects. Biotechnology Advances.DOI
Haiquan Yang, Long Liu, Jianghua Li, Jian Chen, Guocheng Du (2015). Rational Design to Improve Protein Thermostability: Recent Advances and Prospects. ChemBioEng Reviews.DOI
Junli Zhang, Zhen Kang, Jian Chen, Guocheng Du (2015). Optimization of the heme biosynthesis pathway for the production of 5-aminolevulinic acid in Escherichia coli. Scientific Reports.DOI
Chuanzhi Zhang, Junli Zhang, Zhen Kang, Guocheng Du, Jian Chen (2015). Rational engineering of multiple module pathways for the production of l -phenylalanine in Corynebacterium glutamicum. Journal of Industrial Microbiology & Biotechnology.DOI
Hongwei Guo, Peiran Liu, Catherine Madzak, Guocheng Du, Jingwen Zhou, Jian Chen (2015). Identification and application of keto acids transporters in Yarrowia lipolytica. Scientific Reports.DOI
Long Liu, Xin Zhuge, Hyun‐Dong Shin, Rachel R. Chen, Jianghua Li, Guocheng Du, Jian Chen (2015). Improved Production of Propionic Acid in Propionibacterium jensenii via Combinational Overexpression of Glycerol Dehydrogenase and Malate Dehydrogenase from Klebsiella pneumoniae. Applied and Environmental Microbiology.DOI
Zhen Fang, Juan Zhang, Baihong Liu, Guocheng Du, Jian Chen (2015). Insight into the substrate specificity of keratinase KerSMD from Stenotrophomonas maltophilia by site-directed mutagenesis studies in the S1 pocket. RSC Advances.DOI
Raimo Juhani Alén, Murali Anusree, Mario Domingo Baigori, Parameswaran Binod, Rafael Silva Capaz, Guillermo Raul Castro, Coraline Caullet, Miguel Ângelo Cerqueira, Guoqiang Chen, Jian Chen, E. de Jong, Paul J. de Wild, Lilli Dombrowski, Guocheng Du, Bettina Frauz, Balendu Shekher Giri, Mandavi Goswami, Lalitha Devi Gottumukkala, Rainer Höfer, Gerfried Jungmeier, Margarita S. Kambourova, Tyler Kashdan, Ina Körner, Michael Kröger, Jérôme Le Nôtre, Quanfeng Liang, Yanna Liang, Harald Lindorfer, Long Liu, Kesavan Madhavan Nampoothiri, Clarisse Nobre, Luiz Augusto Horta Nogueira, E. Toksoy Oner, Ashok Pandey, Anil Kumar Patel, Licia María Pera, Ingolf Petrick, Annarita Poli, Qingsheng Qi, Lígia R. Rodrigues, Kuttuvan Valappil Sajna, Raveendran Sindhu, Reeta Rani Singhania, Christy Sterner, Rajeev Kumar Sukumaran, José António Teixeira, Leya Thomas, António Augusto Vicente, Ying Wang, Juanyu Zhang (2015). List of Contributors. Elsevier eBooks.DOI
Jian Chen, Guo-Cheng Du, Zhen Kang, Jiang-Hua Li, P. Jin (2014). And a gene encoding hyaluronic acid fermentation and purification methods.
Jian Chen, Guo-Cheng Du, Zhen Kang, P. Jin (2014). Recombinant pichia pastoris for preparing hyaluronic acid and construction method of recombinant pichia pastoris.
Jian Chen, Zhen Kang, Guo-Cheng Du, Jun-Li Zhang (2014). Method for building high-yield 5-aminolevulinic acid escherichia coli engineering strains.
Jian Chen, Guo-Cheng Du, Zhen Kang, P. Jin (2014). Recombinant Pichia pastoris for producing small-molecular hyaluronic acids and construction method thereof.
Ningzi Guan, Jianghua Li, Hyun‐Dong Shin, Jing Wu, Guocheng Du, Zhongping Shi, Long Liu, Jian Chen (2014). Comparative metabolomics analysis of the key metabolic nodes in propionic acid synthesis in Propionibacterium acidipropionici. Metabolomics.DOI
Jun Dai, Linpei Zhang, Zhen Kang, Jian Chen, Guocheng Du (2014). High-level Production of Creatine Amidinohydrolase from Arthrobacter nicotianae 23710 in Escherichia coli. Applied Biochemistry and Biotechnology.DOI
Gazi Sakir Hossain, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Miao Wang, Long Liu, Jian Chen (2014). One-Step Biosynthesis of α-Keto-γ-Methylthiobutyric Acid from L-Methionine by an Escherichia coli Whole-Cell Biocatalyst Expressing an Engineered L-Amino Acid Deaminase from Proteus vulgaris. PLoS ONE.DOI
Yanqiu Zhu, Yanfeng Liu, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Long Liu, Jian Chen (2014). An optimal glucose feeding strategy integrated with step-wise regulation of the dissolved oxygen level improves N-acetylglucosamine production in recombinant Bacillus subtilis. Bioresource Technology.DOI
Lei Gu, Juan Zhang, Baihong Liu, Guocheng Du, Jian Chen (2014). High-Level Extracellular Production of Glucose Oxidase by Recombinant Pichia Pastoris Using a Combined Strategy. Applied Biochemistry and Biotechnology.DOI
Yeon-Hee Lee, Zhi Lin, Guocheng Du, Zhuangmei Deng, Haiquan Yang, Wenxiang Bai (2014). The fungal laccase‐catalyzed oxidation of EGCG and the characterization of its products. Journal of the Science of Food and Agriculture.DOI
Nestor Ishimwe, Eric Daliri, Byong H. Lee, Fang Fang, Guocheng Du (2014). The perspective on cholesterol‐lowering mechanisms of probiotics. Molecular Nutrition & Food Research.DOI
Lei Gu, Juan Zhang, Guocheng Du, Jian Chen (2014). Multivariate modular engineering of the protein secretory pathway for production of heterologous glucose oxidase in Pichia pastoris. Enzyme and Microbial Technology.DOI
Xin Zhuge, Jianghua Li, Hyun‐Dong Shin, Long Liu, Guocheng Du, Jian Chen (2014). Improved propionic acid production with metabolically engineered Propionibacterium jensenii by an oxidoreduction potential-shift control strategy. Bioresource Technology.DOI
Sha Xu, Xiaobei Wang, Guocheng Du, Jingwen Zhou, Jian Chen (2014). Enhanced production of L-sorbose from D-sorbitol by improving the mRNA abundance of sorbitol dehydrogenase in Gluconobacter oxydansWSH-003. Microbial Cell Factories.DOI
Jingwen Zhou, Kui Wang, Sha Xu, Junjun Wu, Peiran Liu, Guocheng Du, Jianghua Li, Jian Chen (2014). Identification of membrane proteins associated with phenylpropanoid tolerance and transport in Escherichia coli BL21. Journal of Proteomics.DOI
Junjun Wu, Oliver S. Yu, Guocheng Du, Jingwen Zhou, Jian Chen (2014). Fine-Tuning of the Fatty Acid Pathway by Synthetic Antisense RNA for Enhanced (2 S )-Naringenin Production from l -Tyrosine in Escherichia coli. Applied and Environmental Microbiology.DOI
Zhen Kang, Sen Yang, Guocheng Du, Jian Chen (2014). Molecular engineering of secretory machinery components for high-level secretion of proteins in Bacillus species. Journal of Industrial Microbiology & Biotechnology.DOI
Yu Yang, Tzu‐Ping Ko, Long Liu, Jianghua Li, Chun‐Hsiang Huang, Hsiu‐Chien Chan, Feifei Ren, Dongxu Jia, Andrew H.‐J. Wang, Rey‐Ting Guo, Jian Chen, Guocheng Du (2014). Inside Cover: Structural Insights into Enzymatic Degradation of Oxidized Polyvinyl Alcohol (ChemBioChem 13/2014). ChemBioChem.DOI
Yu Yang, Tzu‐Ping Ko, Long Liu, Jianghua Li, Chun‐Hsiang Huang, Jian Chen, Rey‐Ting Guo, Guocheng Du (2014). Roles of tryptophan residue and disulfide bond in the variable lid region of oxidized polyvinyl alcohol hydrolase. Biochemical and Biophysical Research Communications.DOI
Junjun Wu, Guocheng Du, Jingwen Zhou, Jian Chen (2014). Systems metabolic engineering of microorganisms to achieve large-scale production of flavonoid scaffolds. Journal of Biotechnology.DOI
Gazi Sakir Hossain, Jianghua Li, Hyun‐Dong Shin, Long Liu, Miao Wang, Guocheng Du, Jian Chen (2014). Improved production of α-ketoglutaric acid (α-KG) by a Bacillus subtilis whole-cell biocatalyst via engineering of l-amino acid deaminase and deletion of the α-KG utilization pathway. Journal of Biotechnology.DOI
Jiran Zhang, Fang Fang, Jian Chen, Guocheng Du (2014). The arginine deiminase pathway of koji bacteria is involved in ethyl carbamate precursor production in soy sauce. FEMS Microbiology Letters.DOI
Yuqing Yang, Zhen Kang, Jianli Zhou, Jian Chen, Guocheng Du (2014). High-level expression and characterization of recombinant acid urease for enzymatic degradation of urea in rice wine. Applied Microbiology and Biotechnology.DOI
Yousef Mohammed, Byong H. Lee, Zhen Kang, Guocheng Du (2014). Development of a two-step cultivation strategy for the production of vitamin B12 by Bacillus megaterium. Microbial Cell Factories.DOI
Yu Yang, Tzu‐Ping Ko, Long Liu, Jianghua Li, Chun‐Hsiang Huang, Hsiu‐Chien Chan, Feifei Ren, Dongxu Jia, Andrew H.‐J. Wang, Rey‐Ting Guo, Jian Chen, Guocheng Du (2014). Structural Insights into Enzymatic Degradation of Oxidized Polyvinyl Alcohol. ChemBioChem.DOI
Junjun Wu, Tiantian Zhou, Guocheng Du, Jingwen Zhou, Jian Chen (2014). Modular Optimization of Heterologous Pathways for De Novo Synthesis of (2S)-Naringenin in Escherichia coli. PLoS ONE.DOI
Sha Xu, Yaqiong Guo, Guocheng Du, Jingwen Zhou, Jian Chen (2014). Self-Cloning Significantly Enhances the Production of Catalase in Bacillus subtilis WSHDZ-01. Applied Biochemistry and Biotechnology.DOI
Wenlong Cao, Zhen Kang, Song Liu, Long Liu, Guocheng Du, Jian Chen (2014). Improved catalytic efficiency of catalase from Bacillus subtilis by rational mutation of Lys114. Process Biochemistry.DOI
Sha Xu, Zhengxiong Zhou, Guocheng Du, Jingwen Zhou, Jian Chen (2014). Efficient transformation of Rhizopus delemar by electroporation of germinated spores. Journal of Microbiological Methods.DOI
Ruizhi Han, Jianghua Li, Hyun‐Dong Shin, Rachel R. Chen, Long Liu, Guocheng Du, Jian Chen (2014). Fusion of Self-Assembling Amphipathic Oligopeptides with Cyclodextrin Glycosyltransferase Improves 2- O - d -Glucopyranosyl- l -Ascorbic Acid Synthesis with Soluble Starch as the Glycosyl Donor. Applied and Environmental Microbiology.DOI
Baihong Liu, Juan Zhang, Zhen Fang, Guocheng Du, Jian Chen, Xiangru Liao (2014). Functional analysis of the C-terminal propeptide of keratinase from Bacillus licheniformis BBE11-1 and its effect on the production of keratinase in Bacillus subtilis. Process Biochemistry.DOI
Yanfeng Liu, Yanqiu Zhu, Wenlong Ma, Hyun‐Dong Shin, Jianghua Li, Long Liu, Guocheng Du, Jian Chen (2014). Spatial modulation of key pathway enzymes by DNA-guided scaffold system and respiration chain engineering for improved N-acetylglucosamine production by Bacillus subtilis. Metabolic Engineering.DOI
Lili Gao, Yudong Hu, Jie Liu, Guocheng Du, Jingwen Zhou, Jian Chen (2014). Stepwise metabolic engineering of Gluconobacter oxydans WSH-003 for the direct production of 2-keto-l-gulonic acid from d-sorbitol. Metabolic Engineering.DOI
Baihong Liu, Juan Zhang, Lei Gu, Guocheng Du, Jian Chen, Xiangru Liao (2014). Comparative Analysis of Bacterial Expression Systems for Keratinase Production. Applied Biochemistry and Biotechnology.DOI
Hongwei Guo, Catherine Madzak, Guocheng Du, Jingwen Zhou, Jian Chen (2014). Effects of pyruvate dehydrogenase subunits overexpression on the α-ketoglutarate production in Yarrowia lipolytica WSH-Z06. Applied Microbiology and Biotechnology.DOI
Peng Kang Jin, Zhen Kang, Na Zhang, Guocheng Du, Jian Chen (2014). High-yield novel leech hyaluronidase to expedite the preparation of specific hyaluronan oligomers. Scientific Reports.DOI
Mengru Zhang, Jian Chen, Juan Zhang, Guocheng Du (2014). The effects of RecO deficiency in Lactococcus lactis NZ9000 on resistance to multiple environmental stresses. Journal of the Science of Food and Agriculture.DOI
Saijie Zhu, Junjun Wu, Guocheng Du, Jingwen Zhou, Jian Chen (2014). Efficient Synthesis of Eriodictyol from l -Tyrosine in Escherichia coli. Applied and Environmental Microbiology.DOI
Lei Feng, Xiufen Li, Ping Song, Guocheng Du, Jian Chen (2014). Physicochemical properties and membrane biofouling of extra-cellular polysaccharide produced by a Micrococcus luteus strain. World Journal of Microbiology and Biotechnology.DOI
Yanfeng Liu, Yanqiu Zhu, Jianghua Li, Hyun‐Dong Shin, Rachel R. Chen, Guocheng Du, Long Liu, Jian Chen (2014). Modular pathway engineering of Bacillus subtilis for improved N-acetylglucosamine production. Metabolic Engineering.DOI
Shaohui Zhao, Xinrui Zhao, Huijun Zou, Jianwei Fu, Guocheng Du, Jingwen Zhou, Jian Chen (2014). Comparative proteomic analysis of Saccharomyces cerevisiae under different nitrogen sources. Journal of Proteomics.DOI
Chuanzhi Zhang, Zhen Kang, Junli Zhang, Guocheng Du, Jian Chen, Xiaobin Yu (2014). Construction and application of novel feedback-resistant 3-deoxy- d -arabino-heptulosonate-7-phosphate synthases by engineering the N-terminal domain for l -phenylalanine synthesis. FEMS Microbiology Letters.DOI
Zhen Kang, Chuanzhi Zhang, Junli Zhang, Peng Kang Jin, Juan Zhang, Guocheng Du, Jian Chen (2014). Small RNA regulators in bacteria: powerful tools for metabolic engineering and synthetic biology. Applied Microbiology and Biotechnology.DOI
Zhen Fang, Juan Zhang, Baihong Liu, Linghuo Jiang, Guocheng Du, Jian Chen (2014). Cloning, heterologous expression and characterization of two keratinases from Stenotrophomonas maltophilia BBE11-1. Process Biochemistry.DOI
Zhenmin Ling, Zhen Kang, Yi Liu, Song Liu, Jian Chen, Guocheng Du (2014). Improvement of catalytic efficiency and thermostability of recombinant Streptomyces griseus trypsin by introducing artificial peptide. World Journal of Microbiology and Biotechnology.DOI
Dongxu Jia, Yu Yang, Zhengcong Peng, Dongxu Zhang, Jianghua Li, Long Liu, Guocheng Du, Jian Chen (2014). High Efficiency Preparation and Characterization of Intact Poly(Vinyl Alcohol) Dehydrogenase from Sphingopyxis sp.113P3 in Escherichia coli by Inclusion Bodies Renaturation. Applied Biochemistry and Biotechnology.DOI
Jian Chen, Guo-Cheng Du, Zhen Kang, Jiang-Hua Li, P. Jin (2013). Efficient recombinant expression method of hyaluronidase.
Ruizhi Han, Jianghua Li, Hyun‐Dong Shin, Rachel R. Chen, Guocheng Du, Long Liu, Jian Chen (2013). Recent advances in discovery, heterologous expression, and molecular engineering of cyclodextrin glycosyltransferase for versatile applications. Biotechnology Advances.DOI
Gazi Sakir Hossain, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Long Liu, Jian Chen (2013). l-Amino acid oxidases from microbial sources: types, properties, functions, and applications. Applied Microbiology and Biotechnology.DOI
Zhen Kang, Chuanzhi Zhang, Guocheng Du, Jian Chen (2013). Metabolic Engineering of Escherichia coli for Production of 2-phenylethanol from Renewable Glucose. Applied Biochemistry and Biotechnology.DOI
Xin Zhuge, Long Liu, Hyun‐Dong Shin, Jianghua Li, Guocheng Du, Jian Chen (2013). Improved propionic acid production from glycerol with metabolically engineered Propionibacterium jensenii by integrating fed-batch culture with a pH-shift control strategy. Bioresource Technology.DOI
Haiquan Yang, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Long Liu, Jian Chen (2013). Molecular engineering of industrial enzymes: recent advances and future prospects. Applied Microbiology and Biotechnology.DOI
Zhuangmei Deng, Haiquan Yang, Jianghua Li, Hyun‐Dong Shin, Guocheng Du, Long Liu, Jian Chen (2013). Structure-based engineering of alkaline α-amylase from alkaliphilic Alkalimonas amylolytica for improved thermostability. Applied Microbiology and Biotechnology.DOI
Kun Du, Zhongmei Liu, Wenjing Cui, Li Zhou, Yi Liu, Guocheng Du, Jian Chen, Zhemin Zhou (2013). pH-Dependent Activation of Streptomyces hygroscopicus Transglutaminase Mediated by Intein. Applied and Environmental Microbiology.DOI
Long Liu, Zhuangmei Deng, Haiquan Yang, Jianghua Li, Hyun‐Dong Shin, Rachel R. Chen, Guocheng Du, Jian Chen (2013). In Silico Rational Design and Systems Engineering of Disulfide Bridges in the Catalytic Domain of an Alkaline α-Amylase from Alkalimonas amylolytica To Improve Thermostability. Applied and Environmental Microbiology.DOI
Xinrui Zhao, Huijun Zou, Jianwei Fu, Jingwen Zhou, Guocheng Du, Jian Chen (2013). Metabolic Engineering of the Regulators in Nitrogen Catabolite Repression To Reduce the Production of Ethyl Carbamate in a Model Rice Wine System. Applied and Environmental Microbiology.DOI
Gazi Sakir Hossain, Jianghua Li, Hyun‐Dong Shin, Rachel R. Chen, Guocheng Du, Long Liu, Jian Chen (2013). Bioconversion of l-glutamic acid to α-ketoglutaric acid by an immobilized whole-cell biocatalyst expressing l-amino acid deaminase from Proteus mirabilis. Journal of Biotechnology.DOI
Jidong Liu, Weiping Zhang, Guocheng Du, Jian Chen, Jingwen Zhou (2013). Overproduction of geraniol by enhanced precursor supply in Saccharomyces cerevisiae. Journal of Biotechnology.DOI
Ruizhi Han, Long Liu, Hyun‐Dong Shin, Rachel R. Chen, Jianghua Li, Guocheng Du, Jian Chen (2013). Iterative Saturation Mutagenesis of −6 Subsite Residues in Cyclodextrin Glycosyltransferase from Paenibacillus macerans To Improve Maltodextrin Specificity for 2- O - d -Glucopyranosyl- l -Ascorbic Acid Synthesis. Applied and Environmental Microbiology.DOI
Long Liu, Haiquan Yang, Hyun‐Dong Shin, Jianghua Li, Guocheng Du, Jian Chen (2013). Recent advances in recombinant protein expression by Corynebacterium, Brevibacterium, and Streptomyces: from transcription and translation regulation to secretion pathway selection. Applied Microbiology and Biotechnology.DOI
Yu Yang, Long Liu, Jianghua Li, Guocheng Du, Jian Chen (2013). Biochemical characterization and high-level production of oxidized polyvinyl alcohol hydrolase from Sphingopyxis sp. 113P3 expressed in methylotrophic Pichia pastoris. Bioprocess and Biosystems Engineering.DOI
Lei Gu, Juan Zhang, Baihong Liu, Chongde Wu, Guocheng Du, Jian Chen (2013). High-level extracellular production of d-Psicose-3-epimerase with recombinant Escherichia coli by a two-stage glycerol feeding approach. Bioprocess and Biosystems Engineering.DOI
Jingwen Zhou, Guocheng Du, Jian Chen (2013). Novel fermentation processes for manufacturing plant natural products. Current Opinion in Biotechnology.DOI
Zhen Kang, Junli Zhang, Sen Yang, Guocheng Du, Jian Chen (2013). [Advances in microbial production of 5-aminolevulinic acid]. PubMed.
Xinrui Zhao, Huijun Zou, Jianwei Fu, Jian Chen, Jingwen Zhou, Guocheng Du (2013). Nitrogen regulation involved in the accumulation of urea in Saccharomyces cerevisiae. Yeast.DOI
Lili Gao, Guocheng Du, Jingwen Zhou, Jian Chen, Jie Liu (2013). Characterization of a group of pyrroloquinoline quinone‐dependent dehydrogenases that are involved in the conversion of L ‐sorbose to 2‐Keto‐ L ‐gulonic acid in Ketogulonicigenium vulgare WSH‐001. Biotechnology Progress.DOI
Zixing Dong, Lei Gu, Juan Zhang, Miao Wang, Guocheng Du, Jian Chen, Huazhong Li (2013). Optimisation for high cell density cultivation of Lactobacillus salivarius BBE 09-18 with response surface methodology. International Dairy Journal.DOI
Haiquan Yang, Long Liu, Hyun‐Dong Shin, Rachel R. Chen, Jianghua Li, Guocheng Du, Jian Chen (2013). Integrating Terminal Truncation and Oligopeptide Fusion for a Novel Protein Engineering Strategy To Improve Specific Activity and Catalytic Efficiency: Alkaline α-Amylase as a Case Study. Applied and Environmental Microbiology.DOI
Junjiao Zhang, Zhen Kang, Zhenmin Ling, Wenlong Cao, Long Liu, Miao Wang, Guocheng Du, Jian Chen (2013). High-level extracellular production of alkaline polygalacturonate lyase in Bacillus subtilis with optimized regulatory elements. Bioresource Technology.DOI
Junjun Wu, Peiran Liu, Yongming Fan, Han Bao, Guocheng Du, Jingwen Zhou, Jian Chen (2013). Multivariate modular metabolic engineering of Escherichia coli to produce resveratrol from l-tyrosine. Journal of Biotechnology.DOI
Qingtao Liu, Long Liu, Jingwen Zhou, Hyun‐Dong Shin, Rachel R. Chen, Catherine Madzak, Jianghua Li, Guocheng Du, Jian Chen (2013). Biosynthesis of homoeriodictyol from eriodictyol by flavone 3′-O-methyltransferase from recombinant Yarrowia lioplytica: Heterologous expression, biochemical characterization, and optimal transformation. Journal of Biotechnology.DOI
Yanfeng Liu, Long Liu, Hyun‐Dong Shin, Rachel R. Chen, Jianghua Li, Guocheng Du, Jian Chen (2013). Pathway engineering of Bacillus subtilis for microbial production of N-acetylglucosamine. Metabolic Engineering.DOI
Zhen Fang, Juan Zhang, Baihong Liu, Guocheng Du, Jian Chen (2013). Corrigendum to “Biochemical characterization of three keratinolytic enzymes from Stenotrophomonas maltophilia BBE11-1 for biodegrading keratin wastes” [Int. Biodeterior. Biodegrad. 82 (2013) 166–172]. International Biodeterioration & Biodegradation.DOI
Jie Bi, Fang Fang, Siyi Lu, Guocheng Du, Jian Chen (2013). New insight into the catalytic properties of bile salt hydrolase. Journal of Molecular Catalysis B Enzymatic.DOI
Xinyao Lu, Song Liu, Yue Min Feng, Shengqi Rao, Xiaoman Zhou, Miao Wang, Guocheng Du, Jian Chen (2013). Enhanced thermal stability of Pseudomonas aeruginosa lipoxygenase through modification of two highly flexible regions. Applied Microbiology and Biotechnology.DOI
Ningzi Guan, Long Liu, Hyun‐Dong Shin, Rachel R. Chen, Juan Zhang, Jianghua Li, Guocheng Du, Zhongping Shi, Jian Chen (2013). Systems-level understanding of how Propionibacterium acidipropionici respond to propionic acid stress at the microenvironment levels: Mechanism and application. Journal of Biotechnology.DOI
Xiaobei Wang, Jie Liu, Guocheng Du, Jingwen Zhou, Jian Chen (2013). Efficient production of l-sorbose from d-sorbitol by whole cell immobilization of Gluconobacter oxydans WSH-003. Biochemical Engineering Journal.DOI
Xinrui Zhao, Guocheng Du, Huijun Zou, Jianwei Fu, Jingwen Zhou, Jian Chen (2013). Progress in preventing the accumulation of ethyl carbamate in alcoholic beverages. Trends in Food Science & Technology.DOI
Long Liu, Yanfeng Liu, Hyun‐Dong Shin, Rachel Chen, Jianghua Li, Guocheng Du, Jian Chen (2013). Microbial production of glucosamine and N-acetylglucosamine: advances and perspectives. Applied Microbiology and Biotechnology.DOI
Long Liu, Yanfeng Liu, Hyun‐Dong Shin, Rachel R. Chen, Nam Sun Wang, Jianghua Li, Guocheng Du, Jian Chen (2013). Developing Bacillus spp. as a cell factory for production of microbial enzymes and industrially important biochemicals in the context of systems and synthetic biology. Applied Microbiology and Biotechnology.DOI
Xin Zhuge, Long Liu, Hyun‐Dong Shin, Rachel R. Chen, Jianghua Li, Guocheng Du, Jian Chen (2013). Development of a Propionibacterium-Escherichia coli Shuttle Vector for Metabolic Engineering of Propionibacterium jensenii, an Efficient Producer of Propionic Acid. Applied and Environmental Microbiology.DOI
Chongde Wu, Juan Zhang, Guocheng Du, Jian Chen (2013). Heterologous expression of Lactobacillus casei RecO improved the multiple-stress tolerance and lactic acid production in Lactococcus lactis NZ9000 during salt stress. Bioresource Technology.DOI
Jingwen Zhou, Qiaoshuang Zheng, Jie Liu, Guocheng Du, Jian Chen (2013). Indigenous plasmids of Bacillus megaterium WSH-002 involved in mutualism with Ketogulonicigenium vulgare WSH-001. Plasmid.DOI
Long Liu, Haiquan Yang, Hyun‐Dong Shin, Rachel R. Chen, Jianghua Li, Guocheng Du, Jian Chen (2013). How to achieve high-level expression of microbial enzymes. Bioengineered.DOI
Long Liu, Qiaoyan Xu, Ruizhi Han, Hyun‐Dong Shin, Rachel R. Chen, Jianghua Li, Guocheng Du, Jian Chen (2013). Improving maltodextrin specificity for enzymatic synthesis of 2-O-d-glucopyranosyl-l-ascorbic acid by site-saturation engineering of subsite-3 in cyclodextrin glycosyltransferase from Paenibacillus macerans. Journal of Biotechnology.DOI
Jidong Liu, Yibo Zhu, Guocheng Du, Jingwen Zhou, Jian Chen (2013). Response of Saccharomyces cerevisiae to D-limonene-induced oxidative stress. Applied Microbiology and Biotechnology.DOI
Zhen Fang, Juan Zhang, Baihong Liu, Guocheng Du, Jian Chen (2013). Biodegradation of wool waste and keratinase production in scale-up fermenter with different strategies by Stenotrophomonas maltophilia BBE11-1. Bioresource Technology.DOI
Baihong Liu, Juan Zhang, Zhen Fang, Lei Gu, Xiangru Liao, Guocheng Du, Jian Chen (2013). Enhanced thermostability of keratinase by computational design and empirical mutation. Journal of Industrial Microbiology & Biotechnology.DOI
Long Liu, Ruizhi Han, Hyun‐Dong Shin, Jianghua Li, Guocheng Du, Jian Chen (2013). Biosynthesis of 2-O-d-glucopyranosyl-l-ascorbic acid from maltose by an engineered cyclodextrin glycosyltransferase from Paenibacillus macerans. Carbohydrate Research.DOI
Zixing Dong, Juan Zhang, Byong H. Lee, Huazhong Li, Guocheng Du, Jian Chen (2013). Secretory expression and characterization of a bile salt hydrolase from Lactobacillus plantarum in Escherichia coli. Journal of Molecular Catalysis B Enzymatic.DOI
Yongkun Lv, Xinrui Zhao, Long Liu, Guocheng Du, Jingwen Zhou, Jian Chen (2013). A simple procedure for protein ubiquitination detection in Saccharomyces cerevisiae: Gap1p as an example. Journal of Microbiological Methods.DOI
Kangkang Chen, Song Liu, Dongxu Zhang, Miao Wang, Zhongping Shi, Guocheng Du, Jian Chen (2013). Altered secretary efficiency of Streptomyces hygroscopicus transglutaminase in Escherichia coli by the pro-peptide modification. Process Biochemistry.DOI
Zhen Fang, Juan Zhang, Baihong Liu, Guocheng Du, Jian Chen (2013). Biochemical characterization of three keratinolytic enzymes from Stenotrophomonas maltophilia BBE11-1 for biodegrading keratin wastes. International Biodeterioration & Biodegradation.DOI
Zhenmin Ling, Yi Liu, Shaolei Teng, Zhen Kang, Jingjing Zhang, Jian Chen, Guocheng Du (2013). Rational Design of a Novel Propeptide for Improving Active Production of Streptomyces griseus Trypsin in Pichia pastoris. Applied and Environmental Microbiology.DOI
Chuanzhi Zhang, Junli Zhang, Zhen Kang, Guocheng Du, Xiaobin Yu, Tianwen Wang, Jian Chen (2013). Enhanced production of l -phenylalanine in Corynebacterium glutamicum due to the introduction of Escherichia coli wild-type gene aroH. Journal of Industrial Microbiology & Biotechnology.DOI
Ruizhi Han, Jianghua Li, Hyun‐Dong Shin, Rachel R. Chen, Guocheng Du, Long Liu, Jian Chen (2013). Carbohydrate-Binding Module–Cyclodextrin Glycosyltransferase Fusion Enables Efficient Synthesis of 2- O - d -Glucopyranosyl- l -Ascorbic Acid with Soluble Starch as the Glycosyl Donor. Applied and Environmental Microbiology.DOI
Haiquan Yang, Long Liu, Hyun‐Dong Shin, Jianghua Li, Guocheng Du, Jian Chen (2013). Structure-Guided Systems-Level Engineering of Oxidation-Prone Methionine Residues in Catalytic Domain of an Alkaline α-Amylase from Alkalimonas amylolytica for Significant Improvement of Both Oxidative Stability and Catalytic Efficiency. PLoS ONE.DOI
Xinyao Lu, Song Liu, Dongxu Zhang, Xiaoman Zhou, Miao Wang, Yi Liu, Jing Wu, Guocheng Du, Jian Chen (2013). Enhanced thermal stability and specific activity of Pseudomonas aeruginosa lipoxygenase by fusing with self-assembling amphipathic peptides. Applied Microbiology and Biotechnology.DOI
Haiquan Yang, Xinyao Lu, Long Liu, Jianghua Li, Hyun‐Dong Shin, Rachel R. Chen, Guocheng Du, Jian Chen (2013). Fusion of an Oligopeptide to the N Terminus of an Alkaline α-Amylase from Alkalimonas amylolytica Simultaneously Improves the Enzyme's Catalytic Efficiency, Thermal Stability, and Resistance to Oxidation. Applied and Environmental Microbiology.DOI
Kangkang Chen, Song Liu, Guang‐Sheng Wang, Dongxu Zhang, Guocheng Du, Jian Chen, Zhongping Shi (2013). Enhancement of Streptomyces transglutaminase activity and pro-peptide cleavage efficiency by introducing linker peptide in the C-terminus of the pro-peptide. Journal of Industrial Microbiology & Biotechnology.DOI
Long Liu, Gazi Sakir Hossain, Hyun‐Dong Shin, Jianghua Li, Guocheng Du, Jian Chen (2013). One-step production of α-ketoglutaric acid from glutamic acid with an engineered l-amino acid deaminase from Proteus mirabilis. Journal of Biotechnology.DOI
Chongde Wu, Juan Zhang, Guocheng Du, Jian Chen (2013). Aspartate protects Lactobacillus casei against acid stress. Applied Microbiology and Biotechnology.DOI
Du Guocheng (2013). Screening of strains for degradation of soybean β-conglycinin and fermentation optimization. Food Science and Technology International.
张娟，吴重德，张梦汝，堵国成，陈坚（2012）. 应用双向荧光差异凝胶技术解析干酪乳杆菌Lactobacillus casei Zhang驯化菌株耐酸胁迫机制. 《工业微生物》.
Baihong Liu, Juan Zhang, Ben Li, Xiangru Liao, Guocheng Du, Jian Chen (2012). Expression and characterization of extreme alkaline, oxidation-resistant keratinase from Bacillus licheniformis in recombinant Bacillus subtilis WB600 expression system and its application in wool fiber processing. World Journal of Microbiology and Biotechnology.DOI
Haiquan Yang, Long Liu, Hyun‐Dong Shin, Rachel R. Chen, Jianghua Li, Guocheng Du, Jian Chen (2012). Structure-based engineering of histidine residues in the catalytic domain of α-amylase from Bacillus subtilis for improved protein stability and catalytic efficiency under acidic conditions. Journal of Biotechnology.DOI
Kangkang Chen, Dongxu Zhang, Song Liu, Nam Sun Wang, Miao Wang, Guocheng Du, Jian Chen (2012). Improvement of transglutaminase production by extending differentiation phase of Streptomyces hygroscopicus: mechanism and application. Applied Microbiology and Biotechnology.DOI
Junjun Wu, Guocheng Du, Jingwen Zhou, Jian Chen (2012). Metabolic engineering of Escherichia coli for (2S)-pinocembrin production from glucose by a modular metabolic strategy. Metabolic Engineering.DOI
Dongxu Jia, Long Liu, Huilin Wang, Dongxu Zhang, Jianghua Li, Guocheng Du, Jian Chen (2012). Overproduction of a truncated poly (vinyl alcohol) dehydrogenase in recombinant Pichia pastoris by low-temperature induction strategy and related mechanism analysis. Bioprocess and Biosystems Engineering.DOI
Ruizhi Han, Long Liu, Hyun‐Dong Shin, Rachel R. Chen, Jianghua Li, Guocheng Du, Jian Chen (2012). Systems Engineering of Tyrosine 195, Tyrosine 260, and Glutamine 265 in Cyclodextrin Glycosyltransferase from Paenibacillus macerans To Enhance Maltodextrin Specificity for 2- O - d -Glucopyranosyl- l -Ascorbic Acid Synthesis. Applied and Environmental Microbiology.DOI
Ruizhi Han, Long Liu, Hyun‐Dong Shin, Rachel R. Chen, Guocheng Du, Jian Chen (2012). Site-saturation engineering of lysine 47 in cyclodextrin glycosyltransferase from Paenibacillus macerans to enhance substrate specificity towards maltodextrin for enzymatic synthesis of 2-O-d-glucopyranosyl-l-ascorbic acid (AA-2G). Applied Microbiology and Biotechnology.DOI
Haiquan Yang, Long Liu, Hyun‐Dong Shin, Rachel R. Chen, Jianghua Li, Guocheng Du, Jian Chen (2012). Comparative analysis of heterologous expression, biochemical characterization optimal production of an alkaline α‐amylase from alkaliphilic Alkalimonas amylolytica in Escherichia coli and Pichia pastoris. Biotechnology Progress.DOI
Jidong Liu, Yibo Zhu, Guocheng Du, Jingwen Zhou, J. Chen (2012). Exogenous ergosterol protects Saccharomyces cerevisiae from d -limonene stress. Journal of Applied Microbiology.DOI
Wenjing Cui, Xiaoyan Yang, Yueqin Fang, Shengmin Zhou, Song Liu, Guocheng Du, Kun Du, Jian Chen, Guanjun Tao, Zhemin Zhou (2012). Discovery of two transglutaminases derived from same zymogen for the Streptomyces hygroscopicus and analysis of their formation processes. Journal of the Science of Food and Agriculture.DOI
Xinyao Lu, Juan Zhang, Song Liu, Dongxu Zhang, Zhihong H. Xu, Jing Wu, Jianghua Li, Guocheng Du, Jian Chen (2012). Overproduction, purification, and characterization of extracellular lipoxygenase of Pseudomonas aeruginosa in Escherichia coli. Applied Microbiology and Biotechnology.DOI
Jingwen Zhou, Hua Liu, Guocheng Du, Jianghua Li, Jian Chen (2012). Production of α-Cyclodextrin Glycosyltransferase in Bacillus megaterium MS941 by Systematic Codon Usage Optimization. Journal of Agricultural and Food Chemistry.DOI
Kangkang Chen, Song Liu, Jianlong Ma, Dongxu Zhang, Zhongping Shi, Guocheng Du, Jian Chen (2012). Deletion combined with saturation mutagenesis of N-terminal residues in transglutaminase from Streptomyces hygroscopicus results in enhanced activity and thermostability. Process Biochemistry.DOI
Huilin Wang, Jianghua Li, Long Liu, Xiaoman Li, Dongxu Jia, Guocheng Du, Jian Chen, Jiangning Song (2012). Increased production of alkaline polygalacturonate lyase in the recombinant Pichia pastoris by controlling cell concentration during continuous culture. Bioresource Technology.DOI
Hua Liu, Jianghua Li, Guocheng Du, Jingwen Zhou, Jian Chen (2012). Enhanced production of α-cyclodextrin glycosyltransferase in Escherichia coli by systematic codon usage optimization. Journal of Industrial Microbiology & Biotechnology.DOI
Haiquan Yang, Long Liu, Jianghua Li, Guocheng Du, Jian Chen (2012). Structure‐based replacement of methionine residues at the catalytic domains with serine significantly improves the oxidative stability of alkaline amylase from alkaliphilic Alkalimonas amylolytica. Biotechnology Progress.DOI
Haiquan Yang, Long Liu, Mingxing Wang, Jianghua Li, Nam Sun Wang, Guocheng Du, Jian Chen (2012). Structure-Based Engineering of Methionine Residues in the Catalytic Cores of Alkaline Amylase from Alkalimonas amylolytica for Improved Oxidative Stability. Applied and Environmental Microbiology.DOI
Lili Gao, Jingwen Zhou, Jie Liu, Guocheng Du, Jian Chen (2012). Draft Genome Sequence of Gluconobacter oxydans WSH-003, a Strain That Is Extremely Tolerant of Saccharides and Alditols. Journal of Bacteriology.DOI
Zhenmin Ling, Tengbo Ma, Jianghua Li, Guocheng Du, Zhen Kang, Jian Chen (2012). Functional expression of trypsin fromStreptomyces griseusbyPichia pastoris. Journal of Industrial Microbiology & Biotechnology.DOI
Jingwen Zhou, Xiaoxia Yin, Catherine Madzak, Guocheng Du, Jian Chen (2012). Enhanced α-ketoglutarate production in Yarrowia lipolytica WSH-Z06 by alteration of the acetyl-CoA metabolism. Journal of Biotechnology.DOI
Chunyu Zhang, Long Liu, Liping Teng, Jinghua Chen, Jinghua Chen, Jian Liu, Jianghua Li, Guocheng Du, Jian Chen, Jian Chen (2012). Metabolic engineering of Escherichia coli BL21 for biosynthesis of heparosan, a bioengineered heparin precursor. Metabolic Engineering.DOI
Zixing Dong, J. Zhang, B. Lee, Hong Li, Guocheng Du, Jian Chen (2012). A bile salt hydrolase gene of Lactobacillus plantarum BBE7 with high cholesterol-removing activity. European Food Research and Technology.DOI
Xiaoxia Yin, Catherine Madzak, Guocheng Du, Jingwen Zhou, Jian Chen (2012). Enhanced alpha-ketoglutaric acid production in Yarrowia lipolytica WSH-Z06 by regulation of the pyruvate carboxylation pathway. Applied Microbiology and Biotechnology.DOI
Ruizhi Han, Long Liu, Jianghua Li, Guocheng Du, Jian Chen (2012). Functions, applications and production of 2-O-d-glucopyranosyl-l-ascorbic acid. Applied Microbiology and Biotechnology.DOI
Feifei Hu, Jidong Liu, Guocheng Du, Zhaozhe Hua, Jingwen Zhou, Jian Chen (2012). Key cytomembrane ABC transporters of Saccharomyces cerevisiae fail to improve the tolerance to d-limonene. Biotechnology Letters.DOI
Zhen Kang, Junli Zhang, Jingwen Zhou, Qingsheng Qi, Guocheng Du, Jian Chen (2012). Recent advances in microbial production of δ-aminolevulinic acid and vitamin B12. Biotechnology Advances.DOI
Juan Zhang, Yin Li, Wei Chen, Guocheng Du, Jian Chen (2012). Glutathione improves the cold resistance of Lactobacillus sanfranciscensis by physiological regulation. Food Microbiology.DOI
Xiaofan Qiu, Tianwen Wang, Xiaomin Zhong, Guocheng Du, Jian Chen (2012). Screening and characterization of an aerobic nitrifying-denitrifying bacterium from activated sludge. Biotechnology and Bioprocess Engineering.DOI
Zongzhong Yu, Guocheng Du, Jingwen Zhou, Jian Chen (2012). Enhanced α-ketoglutaric acid production in Yarrowia lipolytica WSH-Z06 by an improved integrated fed-batch strategy. Bioresource Technology.DOI
Dongxu Jia, Jianghua Li, Long Liu, Dongxu Zhang, Yu Yang, Guocheng Du, Jian Chen (2012). High-level expression, purification, and enzymatic characterization of truncated poly(vinyl alcohol) dehydrogenase in methylotrophic yeast Pichia pastoris. Applied Microbiology and Biotechnology.DOI
Chongde Wu, Juan Zhang, Miao Wang, Guocheng Du, Jian Chen (2012). Lactobacillus casei combats acid stress by maintaining cell membrane functionality. Journal of Industrial Microbiology & Biotechnology.DOI
Yanfeng Liu, Long Liu, Jinghua Chen, Jinghua Chen, Jianghua Li, Guocheng Du, Jian Chen, Jian Chen (2012). Effects of carbon sources and feeding strategies on heparosan production by Escherichia coli K5. Bioprocess and Biosystems Engineering.DOI
Tianwen Wang, Xingyuan Ma, Guocheng Du, Jian Chen (2012). Overview of Regulatory Strategies and Molecular Elements in Metabolic Engineering of Bacteria. Molecular Biotechnology.DOI
Jiaxin Zhang, Long Liu, Jianghua Li, Guocheng Du, Jian Chen (2012). Enhanced glucosamine production by Aspergillus sp. BCRC 31742 based on the time-variant kinetics analysis of dissolved oxygen level. Bioresource Technology.DOI
Du Guocheng (2012). Current Status and Prospects of Enzyme Preparation Industry in China. Journal of Food Science and Biotechnology.
Yibo Zhu, Jie Liu, Guocheng Du, Jingwen Zhou, Jian Chen (2011). Sporulation and spore stability of Bacillus megaterium enhance Ketogulonigenium vulgare propagation and 2-keto-l-gulonic acid biosynthesis. Bioresource Technology.DOI
Xin Chen, Long Liu, Jianghua Li, Guocheng Du, Jian Chen (2011). Improved glucosamine and N-acetylglucosamine production by an engineered Escherichia coli via step-wise regulation of dissolved oxygen level. Bioresource Technology.DOI
Chongde Wu, Juan Zhang, Wei Chen, Miao Wang, Guocheng Du, Jian Chen (2011). A combined physiological and proteomic approach to reveal lactic-acid-induced alterations in Lactobacillus casei Zhang and its mutant with enhanced lactic acid tolerance. Applied Microbiology and Biotechnology.DOI
Song Liu, Dongxu Zhang, Miao Wang, Wenjing Cui, Kangkang Chen, Guocheng Du, Jian Chen, Zhemin Zhou (2011). The order of expression is a key factor in the production of active transglutaminase in Escherichia coli by co-expression with its pro-peptide. Microbial Cell Factories.DOI
Long Liu, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen (2011). Microbial production of hyaluronic acid: current state, challenges, and perspectives. Microbial Cell Factories.DOI
Xin Chen, Long Liu, Jianghua Li, Jie Liu, Guocheng Du, Jian Chen (2011). Optimization of glucose feeding approaches for enhanced glucosamine and N-acetylglucosamine production by an engineered Escherichia coli. Journal of Industrial Microbiology & Biotechnology.DOI
Haiquan Yang, Long Liu, Jianghua Li, Guocheng Du, Jian Chen (2011). Cloning, heterologous expression, and comparative characterization of a mesophilic α-amylase gene from Bacillus subtilis JN16 in Escherichia coli. Annals of Microbiology.DOI
Haiquan Yang, Long Liu, Jianghua Li, Guocheng Du, Jian Chen (2011). Heterologous expression, biochemical characterization, and overproduction of alkaline α-amylase from Bacillus alcalophilus in Bacillus subtilis. Microbial Cell Factories.DOI
Min Li, Xianyan Liao, Dongxu Zhang, Guocheng Du, Jian Chen (2011). Yeast Extract Promotes Cell Growth and Induces Production of Polyvinyl Alcohol-Degrading Enzymes. Enzyme Research.DOI
Jing Wang, Long Liu, Haiyan Zhou, Jianghua Li, Guocheng Du, Jian Chen (2011). Comparative study of L-phenylalanine production in the growing and stationary phases during high cell density cultivation of an auxotrophic Escherichia coli. Biotechnology and Bioprocess Engineering.DOI
Shuying Fang, Jianghua Li, Long Liu, Guocheng Du, Jian Chen (2011). Overproduction of alkaline polygalacturonate lyase in recombinant Escherichia coli by a two-stage glycerol feeding approach. Bioresource Technology.DOI
Song Liu, Dongxu Zhang, Miao Wang, Wenjing Cui, Kangkang Chen, Yi Liu, Guocheng Du, Jian Chen, Zhemin Zhou (2011). The pro-region of Streptomyces hygroscopicus transglutaminase affects its secretion by Escherichia coli. FEMS Microbiology Letters.DOI
Lei Feng, Xiufen Li, Ping Song, Guocheng Du, Jian Chen (2011). Surface Interactions and Fouling Properties of Micrococcus luteus with Microfiltration Membranes. Applied Biochemistry and Biotechnology.DOI
Zhengxiong Zhou, Guocheng Du, Zhaozhe Hua, Jingwen Zhou, Jian Chen (2011). Optimization of fumaric acid production by Rhizopus delemar based on the morphology formation. Bioresource Technology.DOI
Xinhua Wang, Jingmei Li, Xiufen Li, Guocheng Du (2011). Influence of aeration intensity on the performance of A/O-type sequencing batch MBR system treating azo dye wastewater. 《中国环境科学与工程前沿：英文版》.DOI
Yuhong Zhu, Jianghua Li, Long Liu, Guocheng Du, Jian Chen (2011). Production of α-ketoisocaproate via free-whole-cell biotransformation by Rhodococcus opacus DSM 43250 with l-leucine as the substrate. Enzyme and Microbial Technology.DOI
Yu Yang, Dongxu Zhang, Song Liu, Dongxu Jia, Guocheng Du, Jian Chen (2011). Expression and fermentation optimization of oxidized polyvinyl alcohol hydrolase in E. coli. Journal of Industrial Microbiology & Biotechnology.DOI
Zichen Zhang, Jianghua Li, Long Liu, Jun She Sun, Zhaozhe Hua, Guocheng Du, Jian Chen (2011). Enzymatic transformation of 2-O-α-D-glucopyranosyl-L-ascorbic acid by α-cyclodextrin glucanotransferase from recombinant Escherichia coli. Biotechnology and Bioprocess Engineering.DOI
Du Guocheng (2011). Bio-scouring and bleaching of cotton fabric in one bath. Dyeing & Finishing.
Zichen Zhang, Jianghua Li, Long Liu, Jun She Sun, Zhaozhe Hua, Guocheng Du, Jian Chen (2010). Enzymatic transformation of 2-O-α-d-glucopyranosyl-l-ascorbic acid (AA-2G) by immobilized α-cyclodextrin glucanotransferase from recombinant Escherichia coli. Journal of Molecular Catalysis B Enzymatic.DOI
Haiyan Zhou, Xianyan Liao, Long Liu, Tianwen Wang, Guocheng Du, Jian Chen (2010). Enhanced l-phenylalanine production by recombinant Escherichia coli BR-42 (pAP-B03) resistant to bacteriophage BP-1 via a two-stage feeding approach. Journal of Industrial Microbiology & Biotechnology.DOI
Bing‐Jie Ni, He Liu, YanQiu Nie, Raymond Jianxiong Zeng, Guocheng Du, Jian Chen, Han‐Qing Yu (2010). Coupling glucose fermentation and homoacetogenesis for elevated acetate production: Experimental and mathematical approaches. Biotechnology and Bioengineering.DOI
Xiufen Li, Lina Zhang, Guocheng Du (2010). Influence of sludge discharge on sludge settleability and membrane flux in a membrane bioreactor. Environmental Technology.DOI
Haiquan Yang, Jianghua Li, Jun She Sun, Long Liu, Guocheng Du, Jian Chen (2010). Statistical model based optimization of spore production by solid-state culture ofBeauveria bassiana. Biocontrol Science and Technology.DOI
Yunfeng Zhu, Jianghua Li, Ming Tan, Long Liu, Lili Jiang, Jun Sun, Pengsoon Lee, Guocheng Du, Jian Chen (2010). Optimization and scale-up of propionic acid production by propionic acid-tolerant Propionibacterium acidipropionici with glycerol as the carbon source. Bioresource Technology.DOI
Jingwen Zhou, Haiyan Zhou, Guocheng Du, Li Liu, Jian Chen (2010). Screening of a thiamine-auxotrophic yeast for α-ketoglutaric acid overproduction. Letters in Applied Microbiology.DOI
Jianghua Li, Long Liu, Jing Wu, Jun She Sun, Guocheng Du, Jian Chen, Wen‐Yi Tao (2010). Modeling and optimization of cutinase production by recombinant Escherichia coli based on statistical experimental designs. Korean Journal of Chemical Engineering.DOI
Juan Zhang, Guocheng Du, Yanping Zhang, Xianyan Liao, Miao Wang, Yin Li, Jian Chen (2010). Glutathione Protects Lactobacillus sanfranciscensis against Freeze-Thawing, Freeze-Drying, and Cold Treatment. Applied and Environmental Microbiology.DOI
Guobin Liang, Yiwei Mo, Guocheng Du (2010). Optimization of sodium dedecyl sulfate (SDS) addition coupled with adenosine triphosphate (ATP) regeneration for glutathione overproduction in high density cultivation of Candida utilis. Enzyme and Microbial Technology.DOI
Haiyan Zhou, Xianyan Liao, Tianwen Wang, Guocheng Du, Jian Chen (2010). Enhanced l-phenylalanine biosynthesis by co-expression of pheAfbr and aroFwt. Bioresource Technology.DOI
Zhaofeng Li, Bin Li, Zhengbiao Gu, Guocheng Du, Jing Wu, Jian Chen (2010). Extracellular expression and biochemical characterization of α-cyclodextrin glycosyltransferase from Paenibacillus macerans. Carbohydrate Research.DOI
Song Liu, Dongxu Zhang, Long Liu, Miao Wang, Guocheng Du, Jian Chen (2010). Enhanced water absorption of wheat gluten by hydrothermal treatment followed by microbial transglutaminase reaction. Journal of the Science of Food and Agriculture.DOI
Bo Tang, Xianyan Liao, Dongxu Zhang, Min Li, Rong Li, Kelu Yan, Guocheng Du, Jian Chen (2010). Enhanced production of poly(vinyl alcohol)-degrading enzymes by mixed microbial culture using 1,4-butanediol and designed fermentation strategies. Polymer Degradation and Stability.DOI
Gene Drekeke Iyovo, Guocheng Du (2010). Sustainable Bioenergy Bioprocessing: Biomethane Production, Digestate as Biofertilizer and as Supplemental Feed in Algae Cultivation to Promote Algae Biofuel Commercialization. Journal of Microbial & Biochemical Technology.DOI
Zuo-Ping Tan, Shitong Wang, Zhaohong Deng, Guocheng Du (2010). Fermentation process modeling of exopolysaccharide using neural networks and fuzzy systems with entropy criterion. Journal of Biomedical Science and Engineering.DOI
Du Guocheng (2010). Reconstruction Gene Regulatory Network Depend on by Energy Factor. Journal of Food Science and Biotechnology.
Muhammad Salman Qureshi, Dongxu Zhang, Guocheng Du, Jian Chen (2009). Improved production of polygalacturonate lyase by combining a pH and online methanol control strategy in a two-stage induction phase with a shift in the transition phase. Journal of Industrial Microbiology & Biotechnology.DOI
Zhiyu Liu, Dongxu Zhang, Zhaozhe Hua, Jianghua Li, Guocheng Du, Jian Chen (2009). Improvement of laccase production and its properties by low-energy ion implantation. Bioprocess and Biosystems Engineering.DOI
Jianghua Li, Long Liu, Jun Fang, Guocheng Du, Jian Chen (2009). Statistical modeling and optimization for enhanced whole-cell biotransformation synthesis of 2-O-α-d-glucopyranosyl-l-ascorbic acid from maltose and l-ascorbic acid by Aspergillus niger capable of producing α-glucosidase. Journal of Bioscience and Bioengineering.DOI
Guocheng Du, Long Liu, Jianghua Li, Jun Fang, Jian Chen (2009). Process modeling and optimization for enhanced hemicellulase production by Aspergrillus niger using artificial neural network coupling quantum-behaved particle swarm Optimization algorithm. Journal of Bioscience and Bioengineering.DOI
Long Liu, Jun Jie Sun, Miao Wang, Guocheng Du, Jian Chen (2009). Modeling and optimization of mixing performance for enhanced hyaluronic acid production by Streptococcus zooepidemicus using genetic programming coupling quantum-behaved particle swarm optimization algorithm. Journal of Bioscience and Bioengineering.DOI
Zhijian Peng, Jun Fang, Jianghua Li, Guocheng Du, Jian Chen, Xiaoyuan Wang, Jianfei Ning, Liming Cai (2009). Combined dissolved oxygen and pH control strategy to improve the fermentative production of l-isoleucine by Brevibacterium lactofermentum. Journal of Bioscience and Bioengineering.DOI
Zhiyu Liu, Dongxu Zhang, Dapeng Yun, Guocheng Du, Jian Chen (2009). Enhanced laccase production by ion-implanted mutant of Paecilomyces sp. S152. Journal of Bioscience and Bioengineering.DOI
Jun Lin, Xianyan Liao, Guocheng Du, Jian Chen (2009). Use of Escherichia coli add/ade mutant and Saccharomyces cerevisiae WSH2 to construct a highly efficient coupled system for glutathione production. Enzyme and Microbial Technology.DOI
Zhi‐Hao Wang, Yun Wang, Dongxu Zhang, Jianghua Li, Zhaozhe Hua, Guocheng Du, Jian Chen (2009). Enhancement of cell viability and alkaline polygalacturonate lyase production by sorbitol co-feeding with methanol in Pichia pastoris fermentation. Bioresource Technology.DOI
Long Liu, Haiquan Yang, Miao Wang, Guocheng Du, Jian Chen (2009). Statistical modeling and optimization for enhanced hyaluronic acid production by batch culture of Sreptococcus zooepidemicus via the supplement of uracil. Frontiers of Chemical Science and Engineering.DOI
Long Liu, Miao Wang, Jun Sun, Guocheng Du, Jian Chen (2009). Application of a novel cavern volume controlled culture model to microbial hyaluronic acid production by batch culture of Streptococcus zooepidemicus. Biochemical Engineering Journal.DOI
Hejing Yan, Zhaozhe Hua, Guoshi Qian, Miao Wang, Guocheng Du, Jian Chen (2009). Analysis of the chemical composition of cotton seed coat by Fourier-transform infrared (FT-IR) microspectroscopy. Cellulose.DOI
Jun Lin, Xianyan Liao, Juan Zhang, Guocheng Du, Jian Chen (2009). Enhancement of glutathione production with a tripeptidase-deficient recombinant Escherichia coli. Journal of Industrial Microbiology & Biotechnology.DOI
Zhaofeng Li, Jiayu Zhang, Qi Sun, Miao Wang, Zhengbiao Gu, Guocheng Du, Jing Wu, Jian Chen (2009). Mutations of Lysine 47 in Cyclodextrin Glycosyltransferase from Paenibacillus macerans Enhance β-Cyclodextrin Specificity. Journal of Agricultural and Food Chemistry.DOI
Long Liu, Jun Jie Sun, Wenbo Xu, Guocheng Du, Jian Chen (2009). Modeling and optimization of microbial hyaluronic acid production by Streptococcus zooepidemicus using radial basis function neural network coupling quantum‐behaved particle swarm optimization algorithm. Biotechnology Progress.DOI
Lei Feng, Xiufen Li, Guocheng Du, Jian Chen (2009). Adsorption and fouling characterization of Klebsiella oxytoca to microfiltration membranes. Process Biochemistry.DOI
Zhaofeng Li, Zhengbiao Gu, Miao Wang, Guocheng Du, Jing Wu, Jian Chen (2009). Delayed supplementation of glycine enhances extracellular secretion of the recombinant α-cyclodextrin glycosyltransferase in Escherichia coli. Applied Microbiology and Biotechnology.DOI
Zhiyu Liu, Dongxu Zhang, Zhaozhe Hua, Jianghua Li, Guocheng Du, Jian Chen (2009). A newly isolated Paecilomyces sp. WSH-L07 for laccase production: isolation, identification, and production enhancement by complex inducement. Journal of Industrial Microbiology & Biotechnology.DOI
Zhaofeng Li, Bin Li, Zhiguo Liu, Miao Wang, Zhengbiao Gu, Guocheng Du, Jing Wu, Jian Chen (2009). Calcium Leads to Further Increase in Glycine-Enhanced Extracellular Secretion of Recombinant α-Cyclodextrin Glycosyltransferase in Escherichia coli. Journal of Agricultural and Food Chemistry.DOI
Guobin Liang, Guocheng Du, Jian Chen (2009). Salt-induced osmotic stress for glutathione overproduction in Candida utilis. Enzyme and Microbial Technology.DOI
Hejing Yan, Zhaozhe Hua, Guoshi Qian, Miao Wang, Guocheng Du, Jian Chen (2009). Effect of cutinase on the degradation of cotton seed coat in bio-scouring. Biotechnology and Bioprocess Engineering.DOI
Zhijian Peng, Jun Fang, Jianghua Li, Long Liu, Guocheng Du, Jian Chen, Xiaoyuan Wang, Jianfei Ning, Liming Cai (2009). Combined dissolved oxygen and pH control strategy to improve the fermentative production of l-isoleucine by Brevibacterium lactofermentum. Bioprocess and Biosystems Engineering.DOI
Yun Wang, Zhihao Wang, Qing‐Long Xu, Guocheng Du, Zhaozhe Hua, Li Liu, Jianghua Li, Jian Chen (2009). Lowering induction temperature for enhanced production of polygalacturonate lyase in recombinant Pichia pastoris. Process Biochemistry.DOI
Long Liu, Haiquan Yang, Guocheng Du, Jian Chen, Miao Wang (2009). Enhanced Hyaluronic Acid Production ofStreptococcus zooepidemicusby Shifting Dissolved Oxygen Level Based on Broth Rheology and Oxygen Mass Transfer Characteristics. Food Biotechnology.DOI
Dandan Zhang, Nan Liang, Zhongping Shi, Li Liu, Jian Chen, Guocheng Du (2009). Enhancement of α-ketoglutarate production in Torulopsis glabrata: Redistribution of carbon flux from pyruvate to α-ketoglutarate. Biotechnology and Bioprocess Engineering.DOI
Kewei Xu, He Liu, Guocheng Du, Jian Chen (2009). Real-time PCR assays targeting formyltetrahydrofolate synthetase gene to enumerate acetogens in natural and engineered environments. Anaerobe.DOI
Lei Feng, Xiufen Li, Guocheng Du, Jian Chen (2009). Characterization and fouling properties of exopolysaccharide produced by Klebsiella oxytoca. Bioresource Technology.DOI
Long Liu, Guocheng Du, Jian Chen, Miao Wang, Jun Sun (2009). Comparative study on the influence of dissolved oxygen control approaches on the microbial hyaluronic acid production of Streptococcus zooepidemicus. Bioprocess and Biosystems Engineering.DOI
Zhaofeng Li, Jiayu Zhang, Miao Wang, Zhengbiao Gu, Guocheng Du, Jianke Li, Jing Wu, Jian Chen (2009). Mutations at subsite −3 in cyclodextrin glycosyltransferase from Paenibacillus macerans enhancing α-cyclodextrin specificity. Applied Microbiology and Biotechnology.DOI
Gangqiang He, Guanghua Huo, Li Liu, Yang Zhu, Guocheng Du, Jian Chen (2009). Enhanced cutinase production of Thermobifida fusca by a two-stage batch and fed-batch cultivation strategy. Biotechnology and Bioprocess Engineering.DOI
Y.‐Q. Nie, He Liu, Guocheng Du, J. Chen (2009). Acetate production by a coupled syntrophic acetogenesis with homoacetogenesis process: Effect of sludge inoculum concentration. Environmental Technology.DOI
Jun Lin, Xianyan Liao, Guocheng Du, Jian Chen (2009). Enhancement of glutathione production in a coupled system of adenosine deaminase-deficient recombinant Escherichia coli and Saccharomyces cerevisiae. Enzyme and Microbial Technology.DOI
X. L. Liu, He Liu, Guocheng Du, J. Chen (2009). Improved Bioconversion of Volatile Fatty Acids from Waste Activated Sludge by Pretreatment. Water Environment Research.DOI
He Liu, Guangwei Li, Min Zhang, Guocheng Du, Jian Chen (2009). Real-time PCR quantification of ammonia-oxidising bacteria in aerobic granular sludge and activated sludge influenced by pentachlorophenol. International Journal of Environment and Pollution.DOI
Du Guocheng (2009). Mechanism analysis and influence of pH on fouling properties of EPS from membrane fouling layer. Membrane science and technology/Membrane science and technology series.
Du Guocheng (2009). Improvement of MTG Production from Streptomyces hygroscopicus by Fed-batch Fermentation. Zhongguo shengwu gongcheng zazhi.
Du Guocheng (2009). Screening and Breeding of High-yield Transglutaminase (TGase)-producing Streptomyces hygroscopicus Strain Resistant to 2-deoxy-D-Glucose Repression. Food Science.
Du Guocheng (2009). Effect of Solution Chemistry Conditions on Levan Adsorption onto Polyvinylidene Fluoride Membrane. Journal of Food Science and Biotechnology.
Jingwen Zhou, Li Liu, Zhongping Shi, Guocheng Du, Jian Chen (2008). ATP in current biotechnology: Regulation, applications and perspectives. Biotechnology Advances.DOI
Long Liu, Jun Sun, Dongxu Zhang, Guocheng Du, Jian Chen, Wenbo Xu (2008). Culture conditions optimization of hyaluronic acid production by Streptococcus zooepidemicus based on radial basis function neural network and quantum-behaved particle swarm optimization algorithm. Enzyme and Microbial Technology.DOI
Dongxu Zhang, Miao Wang, Jing Wu, Li Cui, Guocheng Du, Jian Chen (2008). Two Different Proteases from Streptomyces hygroscopicus Are Involved in Transglutaminase Activation. Journal of Agricultural and Food Chemistry.DOI
G. Liang, Xianyan Liao, Guocheng Du, J. Chen (2008). Elevated glutathione production by adding precursor amino acids coupled with ATP in high cell density cultivation ofCandida utilis. Journal of Applied Microbiology.DOI
Jingwen Zhou, Li Liu, Guocheng Du, Jian Chen (2008). Citrate protect the growth of Torulopsis glabrata CCTCC M202019 against acidic stress as additional ATP supplier. Journal of Biotechnology.DOI
Zhaofeng Li, Bin Li, Cheng Cheng, Guocheng Du, Jing Wu, Jian Chen (2008). Extracellular expression, purification, and characterization of the recombinant cyclodextrin glycosyltransferase from Peanibacillus macerans. Journal of Biotechnology.DOI
Sha Xu, Li-Ming Liu, Guocheng Du, Jian Chen (2008). Proline protect Torulopsis glabrata against salt stress to enhance pyruvate production. Journal of Biotechnology.DOI
Jingwen Zhou, Zhiyao Dong, Li Liu, Guocheng Du, Jian Chen (2008). A reusable method for construction of non-marker large fragment deletion yeast auxotroph strains: A practice in Torulopsis glabrata. Journal of Microbiological Methods.DOI
Yun Wang, Zhi‐Hao Wang, Guocheng Du, Zhaozhe Hua, Li Liu, Jianghua Li, Jian Chen (2008). Enhancement of alkaline polygalacturonate lyase production in recombinant Pichia pastoris according to the ratio of methanol to cell concentration. Bioresource Technology.DOI
Yang Soo Kim, Weining Huang, Guocheng Du, Zhengxing Pan, Okkyung Kim Chung (2008). Effects of trehalose, transglutaminase, and gum on rheological, fermentation, and baking properties of frozen dough. Food Research International.DOI
Sheng Chen, Xing Tong, Ronald Wesley Woodard, Guocheng Du, Jing Wu, Jian Chen (2008). Identification and Characterization of Bacterial Cutinase. Journal of Biological Chemistry.DOI
Guobin Liang, Xianyan Liao, Guocheng Du, Jian Chen (2008). A new strategy to enhance glutathione production by multiple H2O2-induced oxidative stresses in Candida utilis. Bioresource Technology.DOI
Long Liu, Guocheng Du, Jian Chen, Yang Zhu, Miao Wang, Jun Sun (2008). Microbial production of low molecular weight hyaluronic acid by adding hydrogen peroxide and ascorbate in batch culture of Streptococcus zooepidemicus. Bioresource Technology.DOI
Ling Jun Guo, He Liu, Xin Li, Guocheng Du, Jian Chen (2008). Bioproduction of Volatile Fatty Acids from Excess Municipal Sludge by Multistage Countercurrent Fermentation. Chinese journal of biotechnology/Shengwu gongcheng xuebao.DOI
Long Liu, Guocheng Du, Jian Chen, Miao Wang, Jun Sun (2008). Influence of culture modes on the microbial production of hyaluronic acid by Streptococcus zooepidemicus. Biotechnology and Bioprocess Engineering.DOI
Xiaoling Liu, He Liu, Jinhuan Chen, Jinhuan Chen, Guocheng Du, Jian Chen, Jian Chen (2008). Enhancement of solubilization and acidification of waste activated sludge by pretreatment. Waste Management.DOI
Guobin Liang, Xianyan Liao, Guocheng Du, Jian Chen (2008). Optimization of amino acids addition for efficient production of glutathione in Candida utilis. Biochemical Engineering Journal.DOI
Li Cui, Guocheng Du, Dongxu Zhang, Xuerong Fan, Jian Chen (2008). Stability and conformational changes of transglutaminase from Streptomyces hygroscopicus in ethanol–aqueous medium. Process Biochemistry.DOI
Long Liu, Guocheng Du, Jian Chen, Miao Wang, Jun Sun (2008). Enhanced hyaluronic acid production by a two-stage culture strategy based on the modeling of batch and fed-batch cultivation of Streptococcus zooepidemicus. Bioresource Technology.DOI
Dongxu Zhang, Miao Wang, Guocheng Du, Qingxin Zhao, Jing Wu, Jian Chen (2008). Surfactant Protein of the Streptomyces Subtilisin Inhibitor Family Inhibits Transglutaminase Activation in Streptomyces hygroscopicus. Journal of Agricultural and Food Chemistry.DOI
G YAN, Z HUA, Guocheng Du, Jian Chen (2008). Response of Bacillus sp. F26 to Different Reactive Oxygen Species Stress Characterized by Antioxidative Enzymes Synthesis. Chinese journal of biotechnology/Shengwu gongcheng xuebao.DOI
Guangjie Liang, Guocheng Du, J. Chen (2008). Enhanced glutathione production by using low-pH stress coupled with cysteine addition in the treatment of high cell density culture of Candida utilis. Letters in Applied Microbiology.DOI
Qing-Hao Hu, Xiufen Li, Guocheng Du, Jian Chen (2008). Effect of nitrilotriacetic acid on bioavailability of nickel during methane fermentation. Chemical Engineering Journal.DOI
Long Liu, Guocheng Du, Jian Chen, Maio Wang, Jun Sun (2008). Influence of hyaluronidase addition on the production of hyaluronic acid by batch culture of Streptococcuszooepidemicus. Food Chemistry.DOI
Li Liu, Meng-Qi Wang, Guocheng Du, J. Chen (2008). Enhanced hyaluronic acid production of Streptococcus zooepidemicus by an intermittent alkaline-stress strategy. Letters in Applied Microbiology.DOI
Xianyan Liao, T. Deng, Yuting Zhu, Guocheng Du, J. Chen (2008). Enhancement of glutathione production by altering adenosine metabolism of Escherichia coli in a coupled ATP regeneration system with Saccharomyces cerevisiae. Journal of Applied Microbiology.DOI
Xin Lü, Zhaozhe Hua, Guocheng Du, Xiaolong Ma, Jianhua Cao, Zhanping Yang, Jian Chen (2008). Scavenging of free radicals in gas-phase mainstream cigarette smoke by immobilized catalase at filter level. Free Radical Research.DOI
Li Cui, Guocheng Du, Jian Chen, Qiang Wang, Ping Wang, Xuerong Fan (2008). Effect of microbial transglutaminase on dyeing properties of natural dyes on wool fabric. Biocatalysis and Biotransformation.DOI
Ying Zhang, Guocheng Du, Xuerong Fan, Jian Chen (2008). Effects and statistical optimization of fermentation conditions on growth and poly (vinyl alcohol)-degrading enzyme production ofStreptomyces venezuelaeGY1. Biocatalysis and Biotransformation.DOI
Du Guocheng (2008). GSH Fermentation Process Modeling Based on CCTSK Fuzzy Neural Network. Journal of Food Science and Biotechnology.
Guobin Liang, Guocheng Du, Jian Chen (2007). A novel strategy of enhanced glutathione production in high cell density cultivation of Candida utilis—Cysteine addition combined with dissolved oxygen controlling. Enzyme and Microbial Technology.DOI
Bin Zhuge, Guocheng Du, Wei Shen, Jian Zhuge, Jian Chen (2007). Expression of a Bacillus subtilis pectate lyase gene in Pichia pastoris. Biochemical Engineering Journal.DOI
Junling Shi, Yin Li, Yi Zheng, Yi Zhu, Xiaoping Zhang, Guocheng Du, Jian Chen (2007). Tryptophan supplementation and pH adjustment for optimizing the sporulation of Coniothyrium minitans. Biotechnology Letters.DOI
Zhaofeng Li, Miao Wang, Feng Wang, Zhengbiao Gu, Guocheng Du, Jing Wu, Jian Chen (2007). γ-Cyclodextrin: a review on enzymatic production and applications. Applied Microbiology and Biotechnology.DOI
Li Cui, Guocheng Du, Dongxu Zhang, Jian Chen (2007). Thermal stability and conformational changes of transglutaminase from a newly isolated Streptomyces hygroscopicus. Bioresource Technology.DOI
YanQiu Nie, He Liu, Guocheng Du, Jian Chen (2007). Acetate yield increased by gas circulation and fed-batch fermentation in a novel syntrophic acetogenesis and homoacetogenesis coupling system. Bioresource Technology.DOI
Qing-Hao Hu, Xiufen Li, He Liu, Guocheng Du, Jian Chen (2007). Enhancement of methane fermentation in the presence of Ni2+ chelators. Biochemical Engineering Journal.DOI
Xiufen Li, Yanjun Li, He Liu, Zhaozhe Hua, Guocheng Du, Jian Chen (2007). Correlation between extracellular polymeric substances and aerobic biogranulation in membrane bioreactor. Separation and Purification Technology.DOI
Long Liu, Dengru Liu, Miao Wang, Guocheng Du, Jian Chen (2007). Preparation and characterization of sponge-like composites by cross-linking hyaluronic acid and carboxymethylcellulose sodium with adipic dihydrazide. European Polymer Journal.DOI
Guocheng Du, Li Liu, Zhaoxia Song, Zhaozhe Hua, Yang Zhu, Jian Chen (2007). Production of polyvinyl alcohol‐degrading enzyme with Janthinobacterium sp. and its application in cotton fabric desizing. Biotechnology Journal.DOI
Guocheng Du, Zhang Shou-liang, Zhaozhe Hua, Yang Zhu, Jian Chen (2007). Enhanced cutinase production with Thermobifida fusca by two‐stage pH control strategy. Biotechnology Journal.DOI
Guangwei Li, He Liu, Feng Zhang, Guocheng Du, Jian Chen (2007). [Real time PCR quantification of ammonia-oxidizing bacteria in aerobic granular sludge and activated sludge influenced by pentachlorophenol]. PubMed.
Yu Deng, Dengru Liu, Guocheng Du, Xiufen Li, Jian Chen (2007). Preparation and characterization of hyaluronan/chitosan scaffold cross‐ linked by 1‐ethyl‐3‐(3‐dimethylaminopropyl) carbodiimide. Polymer International.DOI
Bin Zhuge, Guocheng Du, Wei Shen, Jian Zhuge, Jian Chen (2007). Efficient secretory expression of an alkaline pectate lyase gene from Bacillus subtilis in E. coli and the purification and characterization of the protein. Biotechnology Letters.DOI
Zhaozhe Hua, Guoliang Yan, Guocheng Du, Jian Chen, Jian Chen (2007). Study and improvement of the conditions for production of a novel alkali stable catalase. Biotechnology Journal.DOI
Li Cui, Guocheng Du, Dongxu Zhang, He Liu, Jian Chen (2007). Purification and characterization of transglutaminase from a newly isolated Streptomyces hygroscopicus. Food Chemistry.DOI
Du Guocheng (2007). Factors and Mechanism of ATP Biosynthesis by the Cells of Saccharomyces cerevisiae. Journal of Food Science and Biotechnology.
Pan Chun-mei, Bian Chuanzhou, Xiaojing Zhang, Du Guocheng (2007). Effects of promoters on CoQ_(10) fermentation. Industrial Microbiology.
Du Guocheng (2006). Treatment of pharmaceutical wastewater by aerobic jet-loop compact reactor. Industrial Water & Wastewater.
Du Guocheng (2006). Mutagenesis of cutinase-producing strain Thermobifida fusca WSH03-11 and optimization of fermentation conditions of mutant with high cutinase production. Huagong jinzhan.
Guocheng Du, Li Cui, Yang Zhu, Jian Chen (2006). Improvement of shrink-resistance and tensile strength of wool fabric treated with a novel microbial transglutaminase from Streptomyces hygroscopicus. Enzyme and Microbial Technology.DOI
Li Liu, Qing‐Long Xu, Yin Li, Zhongpin Shi, Yang Zhu, Guocheng Du, Jian Chen (2006). Enhancement of pyruvate production by osmotic‐tolerant mutant of Torulopsis glabrata. Biotechnology and Bioengineering.DOI
YanQiu Nie, He Liu, Guocheng Du, Jian Chen (2006). Enhancement of acetate production by a novel coupled syntrophic acetogenesis with homoacetogenesis process. Process Biochemistry.DOI
Xiufen Li, Yanjun Li, He Liu, Zhaozhe Hua, Guocheng Du, Jian Chen (2006). Characteristics of aerobic biogranules from membrane bioreactor system. Journal of Membrane Science.DOI
Jian Chen, Ying Zhang, Guocheng Du, Zhaozhe Hua, Yang Zhu (2006). Biodegradation of polyvinyl alcohol by a mixed microbial culture. Enzyme and Microbial Technology.DOI
Jian Chen, Qiang Wang, Zhaozhe Hua, Guocheng Du (2006). Research and application of biotechnology in textile industries in China. Enzyme and Microbial Technology.DOI
Li Liu, Yin Li, Yang Zhu, Guocheng Du, Jian Chen (2006). Redistribution of carbon flux in Torulopsis glabrata by altering vitamin and calcium level. Metabolic Engineering.DOI
Zhaozhe Hua, Song Ruohai, Guocheng Du, Huazhong Li, Jian Chen (2006). Effects of EDTA and Tween60 on biodegradation of n-hexadecane with two strains of Pseudomonas aeruginosa. Biochemical Engineering Journal.DOI
Li Liu, Yin Li, Zhongping Shi, Guocheng Du, Jian Chen (2006). Enhancement of pyruvate productivity in Torulopsis glabrata: Increase of NAD+ availability. Journal of Biotechnology.DOI
Xianyan Liao, Wei Shen, J. Chen, Yin Li, Guocheng Du (2006). Improved glutathione production by gene expression in Escherichia coli. Letters in Applied Microbiology.DOI
Feng Wang, Guocheng Du, Yin Li, Jian Chen (2006). Regulation of CCR in the γ-CGTase production from Bacillus macorous by the specific cell growth rate control. Enzyme and Microbial Technology.DOI
Li Liu, Yin Li, Guocheng Du, J. Chen (2006). Increasing glycolytic flux in Torulopsis glabrata by redirecting ATP production from oxidative phosphorylation to substrate-level phosphorylation. Journal of Applied Microbiology.DOI
Haijun Gao, Guocheng Du, Jian Chen (2006). Analysis of metabolic fluxes for hyaluronic acid (HA) production by Streptococcus zooepidemicus. World Journal of Microbiology and Biotechnology.DOI
Hua Zou, Guocheng Du, Wenquan Ruan, Jian Chen (2006). Role of nitrate in biological phosphorus removal in a sequencing batch reactor. World Journal of Microbiology and Biotechnology.DOI
Guoliang Yan, Zhaozhe Hua, Guocheng Du, Jian Chen (2006). Adaptive Response of Bacillus sp. F26 to Hydrogen Peroxide and Menadione. Current Microbiology.DOI
Li Cui, Dongxu Zhang, Huang Liang, He Liu, Guocheng Du, Jian Chen (2006). Stabilization of a new microbial transglutaminase from Streptomyces hygroscopicus WSH03-13 by spray drying. Process Biochemistry.DOI
Li Liu, Yin Li, Guocheng Du, Jian Chen (2006). Redirection of the NADH oxidation pathway in Torulopsis glabrata leads to an enhanced pyruvate production. Applied Microbiology and Biotechnology.DOI
Du Guocheng (2006). Enhancement of hyaluronic acid production by Streptococcus zooepidemicus H24 through supplement of CTAB. Huagong jinzhan.
Du Guocheng (2006). Study on Improvement of Cryopreservation of Lactic Acid Bacteria in Frozen Sourdough Starters during Freezing and Frozen-Storage. Food Science.
Guoliang Yan, Zhaozhe Hua, Dengru Liu, Guocheng Du, Jian Chen (2005). Influence of oxygen level on oxidative stress response of Bacillus sp. F26 to menadione. Process Biochemistry.DOI
Li Ma, Xiufen Li, Guocheng Du, Jian Chen, Zhisong Shen (2005). Influence of the filtration modes on colloid adsorption on the membrane in submerged membrane bioreactor. Colloids and Surfaces A Physicochemical and Engineering Aspects.DOI
Xiufen Li, Fangshu Gao, Zhaozhe Hua, Guocheng Du, Jian Chen (2005). Treatment of synthetic wastewater by a novel MBR with granular sludge developed for controlling membrane fouling. Separation and Purification Technology.DOI
Xin Chen, Yin Li, Guocheng Du, Jian Chen (2005). Application of response surface methodology in medium optimization for spore production of Coniothyrium minitans in solid-state fermentation. World Journal of Microbiology and Biotechnology.DOI
Feng Wang, Guocheng Du, Yin Li, Jian Chen (2005). Effects of dissolved oxygen concentration and two-stage oxygen supply strategy on the production of γ-CGTase by Bacillus macorous. Process Biochemistry.DOI
W. Nie, Gongyuan Wei, Guocheng Du, Yin Li, J. Chen (2005). Enhanced intracellular glutathione synthesis and excretion capability of Candida utilis by using a low pH-stress strategy. Letters in Applied Microbiology.DOI
Li-Ming Liu, Guocheng Du, Yin Li, Huazhong Li, Jian Chen (2005). Enhancement of pyruvate production byTorulopsis glabrata through supplement of oxaloacetate as carbon source. Biotechnology and Bioprocess Engineering.DOI
Junling Shi, Yin Li, Qian Huali, Guocheng Du, Chen Jian (2004). Pre-germinated conidia of Coniothyrium minitans enhances the foliar biological control of Sclerotinia sclerotiorum. Biotechnology Letters.DOI
Guocheng Du, Ge Hoa Yang, Yinbo Qu, Jian Chen, Shiyi Lun (2004). Effects of glycerol on the production of poly(γ-glutamic acid) by Bacillus licheniformis. Process Biochemistry.DOI
Ding Qian, Guocheng Du, Jian Chen (2004). Isolation and Culture Characterization of a New Polyvinyl Alcohol-Degrading Strain: Penicillium sp. WSH02-21. World Journal of Microbiology and Biotechnology.DOI
Guoliang Yan, Guocheng Du, Yin Li, Jian Chen, Jian‐Jiang Zhong (2004). Enhancement of microbial transglutaminase production by Streptoverticillium mobaraense: application of a two-stage agitation speed control strategy. Process Biochemistry.DOI
Zhaozhe Hua, Yan Chen, Guocheng Du, Jian Chen (2004). Effects of biosurfactants produced by Candida antarctica on the biodegradation of petroleum compounds. World Journal of Microbiology and Biotechnology.DOI
Feng Wang, Guocheng Du, Yin Li, Jian Chen (2004). Optimization of Cultivation Conditions for the Production of γ-Cyclodextrin Glucanotransferase byBacillus macorous. Food Biotechnology.DOI
Yin Li, Ning He, Hao Guan, Guocheng Du, J. Chen (2003). A novel polygalacturonic acid bioflocculant REA-11 produced by Corynebacterium glutamicum : a proposed biosynthetic pathway and experimental confirmation. Applied Microbiology and Biotechnology.DOI
Zufang Wu, Guocheng Du, Jian Chen (2003). Effects of dissolved oxygen concentration and DO-stat feeding strategy on CoQ10 production with Rhizobium radiobacter. World Journal of Microbiology and Biotechnology.DOI
Qiang Wang, Guocheng Du, Jian Chen (2003). Aerobic granular sludge cultivated under the selective pressure as a driving force. Process Biochemistry.DOI
Qun Yan, Guocheng Du, Jian Chen (2003). Biosynthesis of polyhydroxyalkanoates (PHAs) with continuous feeding of mixed organic acids as carbon sources by Ralstonia eutropha. Process Biochemistry.DOI
Guocheng Du, Jinju Geng, Jian Chen, Shiyi Lun (2003). Mixed culture of nitrifying bacteria and denitrifying bacteria for simultaneous nitrification and denitrification. World Journal of Microbiology and Biotechnology.DOI
Gongyuan Wei, Yin Li, Guocheng Du, Jian Chen (2003). Effect of surfactants on extracellular accumulation of glutathione by Saccharomyces cerevisiae. Process Biochemistry.DOI
Meiying Zheng, Du Guocheng, Chen Jian (2002). pH control strategy of batch microbial transglutaminase production with Streptoverticillium mobaraense. Enzyme and Microbial Technology.DOI
Du Guocheng (2002). The Research on Environmental Enzyme Preparation and Its Current Application. Journal of Suzhou Institute of Urban Construction and Environmental Protection.
Meiying Zheng, Guocheng Du, Jian Chen, Shiyi Lun (2002). Modelling of temperature effects on batch microbial transglutaminase fermentation with Streptoverticillium mobaraense. World Journal of Microbiology and Biotechnology.DOI
Yanan Wang, Le Zeng, Tianxi Sun, Pengfei Sun, Hanyun Jiang, Guocheng Du, Jian Chen, Xiao Liu (2025). From insoluble aggregates to nano-dispersible yeast protein for stabilizing high internal phase emulsions with rheological and oral perception improvements. SSRN Electronic Journal.DOI
书籍章节
Chenyang Zhang, Mengyue Gong, Xueqin Lv, Yanfeng Liu, Long Liu, Guocheng Du (2022). Analysis and modeling tools of metabolic flux. Elsevier eBooks.DOI
Yonglin Zhang, Yang Wang, Jianghua Li, Chao Wang, Guocheng Du, Zhen Kang (2022). Construction of Strong Promoters by Assembling Sigma Factor Binding Motifs. Methods in molecular biology.DOI
Qinghua Li, Guoqiang Zhang, Guocheng Du (2021). Production of food enzymes. Elsevier eBooks.DOI
Yaokang Wu, Guocheng Du, Jian Chen, Long Liu (2020). Genetically Encoded Biosensors and Their Applications in the Development of Microbial Cell Factories. Springer eBooks.DOI
Guoqiang Zhang, Yukun Chen, Guocheng Du (2020). Protein engineering approaches for enhanced catalytic efficiency. Elsevier eBooks.DOI
Xianhao Xu, Yanfeng Liu, Guocheng Du, Long Liu (2020). Systems biology, synthetic biology, and metabolic engineering. Elsevier eBooks.DOI
Rongzhen Tian, Guocheng Du, Yanfeng Liu (2020). Refactoring and optimization of metabolic network. Elsevier eBooks.DOI
Yaokang Wu, Xueqin Lv, Yanfeng Liu, Guocheng Du, Long Liu (2020). Systems and synthetic metabolic engineering for production of biochemicals. Elsevier eBooks.DOI
Yanfeng Liu, Yanting Cao, Guocheng Du, Long Liu (2020). Systems and synthetic metabolic engineering: Challenges and prospects. Elsevier eBooks.DOI
Haiquan Yang, Fengyu Qin, Zilong Wang, Xianzhong Chen, Guocheng Du (2020). Biotransformations with crude enzymes and whole cells. Elsevier eBooks.DOI
Deng Chen, Tingting Huang, Zhu Jiang, Xueqin Lv, Long Liu, Jian Chen, Guocheng Du (2019). Enzyme Engineering and Industrial Bioprocess. Elsevier eBooks.DOI
Yaokang Wu, Yang Mo Gu, Rongzhen Tian, Guocheng Du, Jian Chen, Long Liu (2019). Construction of Microbial Cell Factories by Systems and Synthetic Biotechnology. Springer eBooks.DOI
Panhong Yuan, Shixiu Cui, Jianghua Li, Guocheng Du, Jian Chen, Long Liu (2019). Microbial Production of Vitamins. Springer eBooks.DOI
Xueqin Lv, Jingjing Liu, Xian Yin, Liuyan Gu, Li Sun, Guocheng Du, Jian Chen, Long Liu (2019). Microbial Production of Functional Organic Acids. Springer eBooks.DOI
Ningzi Guan, Jianghua Li, Guocheng Du, Jian Chen, Long Liu (2019). Microbial Production of Nutraceuticals: Challenges and Prospects. Springer eBooks.DOI
Zhen Kang, Wenwen Ding, Peng Kang Jin, Guocheng Du, Jian Chen (2018). DNA Assembly with the DATEL Method. Methods in molecular biology.DOI
Zhen Kang, Wenwen Ding, Peng Kang Jin, Guocheng Du, Jian Chen (2018). Combinatorial Evolution of DNA with RECODE. Methods in molecular biology.DOI
Gazi Sakir Hossain, Lijun Liu, Guocheng Du (2016). Industrial Bioprocesses and the Biorefinery Concept. Elsevier eBooks.DOI
Haiquan Yang, Jianghua Li, Guocheng Du, Long Liu (2016). Microbial Production and Molecular Engineering of Industrial Enzymes. Elsevier eBooks.DOI
Guocheng Du, Long Liu, Jian Chen (2015). White Biotechnology for Organic Acids. Elsevier eBooks.DOI
Jingwen Zhou, Li Liu, Guocheng Du, Jian Chen (2014). Biolistic Transformation of Candida glabrata for Homoplasmic Mitochondrial Genome Transformants. Fungal biology.DOI
Jingwen Zhou, Guocheng Du, Jian Chen (2012). Metabolic Engineering of Microorganisms for Vitamin C Production. Sub-cellular biochemistry/Subcellular biochemistry.DOI
Juan Zhang, Chongde Wu, Feng Xue, Guocheng Du, Jian Chen (2011). Stress Responses of Lactococcus lactis. Springer eBooks.DOI