百晓学者学者目录

孙昊鹏

副教授、教授、研究员、讲师，中国药科大学

精选作品

期刊论文

2026

靶向DPP4多靶点干预策略治疗糖尿病的研究进展

陈梦销，孙昊鹏

《井冈山大学学报(自然科学版)》

2026

Biomimetic nanodelivery of antagomiR-155-5p ameliorates wear particle-induced osteolysis by dual regulation of Gas6/Axl-mediated macrophage inflammation

Taihe Liu, Si-Peng Lin, C. Pan, Yifan Yu, Haopeng Sun, Jun-Xi Chen, Muyun Tan, Chang-Chuan Li, Shi-Xun Li, Si-Yuan Tan, G. Zeng, Haoxian Liu, W. Ko, Jing Xu, Yujun Sun, P. Saw, Yue Ding

Journal of Orthopaedic Translation

DOI

2026

Nanoparticle-Loaded Injectable Hydrogel Alleviates Titanium Particle-Induced Osteolysis by Disrupting GATA6/DDX3X-Mediated Macrophage Inflammation

Si-Peng Lin, Taihe Liu, Qi Zhu, Z. Ouyang, Yifan Yu, Haopeng Sun, Chang-Chuan Li, Shi-Xun Li, C. Pan, W. Ko, Haoxian Liu, Jin M. Liu, Shuangxing Li, Jinchang Chen, Shaojia Wu, Jichao Ye, Liangbin Gao, Yue Ding

Biomaterials Research

DOI

2026

STAT1 itaconation prevents macrophage cytolistic mtDNA -induced inflammation in wear particle-induced aseptic loosening

Yi-Fan Yu, Taihe Liu, C. Pan, Haopeng Sun, Zhipeng Chen, Haoxian Liu, W. Ko, Si-Yuan Tan, Jiankai Luo, Shi-Xun Li, Chang-Chuan Li, Yue Ding

Cell Communication and Signaling

DOI

2026

Discovery of a BBB-Penetrant Lanosterol Derivative as an Aβ Aggregation Inhibitor for Alzheimer’s Disease

Baichen Xiong, Tengfei Zhen, Xinhai Wang, Weiting Zhang, Wang Zhiqiang, Mingkang Ma, Xiaoxue Bai, Jiawei Zhu, Na Zheng, Yuqing Wei, Mengxiao Chen, Pengkun Sun, Bingbing Lv, Chenyu Zhang, Ziyu Cao, Yuanyuan Wang, 白賢淑, Wenyuan Liu, Chaojun Wang, Yue Wu, Yao Chen, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2026

Current landscape and future perspectives of small-molecule therapeutics for Huntington's disease: From rational design to clinical translation

Yitian Jiang, Xinyi Chen, Zhaoxin Xu, Xiao Chen, Qinjie Wang, Junying Ma, Xiyang Wu, Guangyao Deng, Simeng Li, Haopeng Sun, Yao Chen

European Journal of Medicinal Chemistry

DOI

2026

Design, Synthesis, and Biological Evaluation of a Cathepsin B-Activated Small Molecule-Drug Conjugate Targeting AKR1C3 to Enhance Chemotherapeutic Selectivity

Wang Xl, Can Guo, Yimeng Liu, Bingjie Han, Li Zhang, Zongliang Liu, Yuehua Chen, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2026

Target-driven machine learning–enabled virtual screening (TAME-VS) enables prioritization of AKR1C3 inhibitors

Longjiang Qiao, Xinyu Li, Shuaishuai Xing, Qianwen Guan, Kun Ning, Weijie Han, Luyu Zhang, Anlan Dai, Weiqi Yang, Y Liu, Jason J. Kwon, Xin Gao, Haopeng Sun, Yuemin Bian

Communications Chemistry

DOI

2026

Rewiring cell death and evading repair: Evolution of temozolomide and emerging strategies against resistant glioblastoma

Lu Wang, Tengfei Zhen, Hui Liu, Pengkun Sun, Xiyang Wu, Y C Chen, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2026

Unlocking new frontiers in AKR1B10 inhibition and future opportunities

Sanzida Yeasrim, Hafiz Tanveer Ahmad, Mengxiao Chen, Xinyu Li, Ziming Gao, Haopeng Sun, Shuaishuai Xing

European Journal of Medicinal Chemistry

DOI

2026

Development of tacrine-based multitarget-directed ligands as dual AChE/EGFR inhibitors with neuroprotective activity

Yuqing Wei, Ao Zhang, Weimin Qiu, Baichen Xiong, Zuoaoyun Song, Na Zheng, Yingjia Wu, Chenyu Zhang, Ziyu Cao, Xinhai Wang, Chunlei Xu, Qun Zhao, Yulan Wu, Zongliang Liu, Yao Chen, Haopeng Sun

Bioorganic & Medicinal Chemistry

DOI

2026

Aldo‐Keto Reductase Family 1 Member B10 as a Therapeutic Frontier: Advances in Inhibitor Design and Multimodal Approaches

Jikuan Shao, Xing Wang, Can Guo, Shuaishuai Xing, Haopeng Sun

Medicinal Research Reviews

DOI

2026

A strategy for improving blood−brain barrier permeability of ChE inhibitors through blood-brain barrier (BBB) transporter

Ziming Gao, Yanyu Hu, Na Zheng, Qinghua Wang, Chenlong Xie, Mengxiao Chen, Mengxiao Chen, Sanzida Yeasrim, Lan Wang, Tianyu Zhang, Zhibo Jia, Pengkun Sun, Pengkun Sun, Yaning Li, Chunlei Xu, Qun Zhao, Yulan Wu, Yao Chen, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2026

Sculpting Cell Fate: The Expanding Universe of Nondegradative Proximity‐Inducing Tools

Hangdi Xiao, Lan Wang, Mengxiao Chen, Tengfei Zhen, Yao Chen, Haopeng Sun

ChemMedChem

DOI

2026

Discovery of Highly Selective AKR1C3 Inhibitors to Overcome EGFR C797S-Mediated Osimertinib Resistance in Non-Small Cell Lung Cancer

Can Guo, Xing Wang, Qianwen Guan, Sheng Zhong, Lu Zhang, Yi Liu, Bingjie Han, Jikuan Shao, Zongliang Liu, Yao Chen, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2026

2‐(Diphenylphosphinoyl)acetyl Group Enabled Divergent Synthesis of 2′‐ O ‐Acetyl Phenylethanoid Glycosides

Kai Liu, Longxing Tang, Wenyi Peng, Xiangjia Xu, Ziming Gao, Haopeng Sun, Weijia Xie, Wei Li, Z ZHANG

Chemistry - A European Journal

DOI

2026

Lanolin-derived bioactive fractions promote infected wound healing via synergistic anti-inflammatory and pro-survival effects

Xinhai Wang, Pilin Huang, Baichen Xiong, Yuqing Wei, Xiaoxue Bai, Chenyu Zhang, Chaojun Wang, Yue Wu, Feng Feng, Sun HaoPeng, Yao Chen

Natural Product Research

DOI

2025

Small Molecule-Drug Conjugates: An Emerging Drug Design Strategy for Targeted Therapeutics

Xiaolong Wang, Can Guo, Jikuan Shao, Xinyu Zou, Shuaishuai Xing, Xu Chen, Qun Zhao, Yulan Wu, Chengliang Sun, Yao Chen, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2025

From concept to application: Exploring the evolution and potential of DUBTAC technology

Danfeng Wang, Wenjian Min, Binjian Jiang, Haopeng Sun, Chengliang Sun, Peng Yang

Acta Pharmaceutica Sinica B

DOI

2025

Discovery of Novel Selective Inhibitors of SMARCA2 ATPase Domain by Virtual Screening and Biological Evaluation

Jiawei Zhu, Xiaoxue Bai, Yucheng Xiong, Chenlong Xie, Yao Chen, Haopeng Sun

ACS Medicinal Chemistry Letters

DOI

2025

Aging and anti-aging strategies: A review of past and future therapeutics

Yuqing Wei, Baichen Xiong, Zuoaoyun Song, Sheng Zhong, Na Zheng, Ao Zhang, Yao Chen, Haopeng Sun

Bioorganic & Medicinal Chemistry

DOI

2025

Chiral switch of a butyrylcholinesterase inhibitor for the treatment of Alzheimer's disease

Urban Košak, Damijan Knez, Svit Ferjančič Benetik, Peter Mastnak Sokolov, Anja Hafner Pišlar, Selena Horvat, Jure Stojan, Bingbing Lv, Weiting Zhang, Yuanyuan Wang, Qinjie Wang, Alexandre Igert, José Dias, Florian Nachon, Xavier Brazzolotto, Haopeng Sun, Stanislav Gobec

Chemico-Biological Interactions

DOI

2025

Pleiotropic prodrugs for both symptomatic and disease-modifying treatment of Alzheimer’s disease

A. Meden, Neža Žnidaršič, Damijan Knez, Yuanyuan Wang, Ziwei Xu, Huajing Yang, Weiting Zhang, Anja Hafner Pišlar, Andrej Perdih, Simona Kranjc, Neža Grgurevič, Stane Pajk, Haopeng Sun, Stanislav Gobec

Acta Pharmaceutica Sinica B

DOI

2025

Lead Optimization of a Butyrylcholinesterase Inhibitor for the Treatment of Alzheimer’s Disease

Urban Košak, Nika Strašek Benedik, Damijan Knez, Simon Žakelj, Jurij Trontelj, Anja Hafner Pišlar, Selena Horvat, Aljoša Bolje, Neža Žnidaršič, Neža Grgurevič, Tanja Švara, Jakob Kljun, Anna Skrzypczak-Wiercioch, Bingbing Lv, Yucheng Xiong, Qinjie Wang, Rui Bian, Jikuan Shao, José Dias, Florian Nachon, Xavier Brazzolotto, Jure Stojan, Haopeng Sun, Kinga Sałat, Stanislav Gobec

Journal of Medicinal Chemistry

DOI

2025

Clinical Investigation of Tyrosinase Inhibitors: Past, Present, and Future

Yuan Yuan Wang, Ruijia Jiang, Baichen Xiong, Jiawei Zhu, Jingjing Sang, Hongtao Li, Chen Chen, Ziwei Xu, Weiting Zhang, Yao Chen, Feng Feng, Haopeng Sun

Drug Development Research

DOI

2025

Dual inhibitors of butyrylcholinesterase and histone deacetylase 6 for the treatment of Alzheimer’s disease: design, synthesis, and biological evaluation

Bingbing Lv, Zhenqi Wang, Qinjie Wang, Zesheng Xu, Jixiong Tang, Yuqiong Pei, Yaoyao Bian, Haopeng Sun, Yao Chen

Bioorganic & Medicinal Chemistry

DOI

2025

Brief analysis of Nav1.7 inhibitors: Mechanism of action and new research trends

Zhoujun Dong, Baichen Xiong, Tian‐Yu Sun, Tianyu Sun, Ruijia Jiang, Feng Feng, Haopeng Sun

Bioorganic & Medicinal Chemistry

DOI

2025

Discovery of Highly Potent AKR1C3 Inhibitors Treating Sorafenib-Resistant Hepatocellular Carcinoma

Shuaishuai Xing, Jiheng Jiang, Xianglin Chu, Xiaolong Wang, Zhiqiang Wang, Xinyu Li, Bingbing Lv, Can Guo, Siyu He, Leyan Wang, Chenyu Zhang, Qinglong Guo, Li Zhao, Pengfei Fang, Feng Feng, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2025

Discovery of highly potent AKR1Cs pan-inhibitors as chemotherapeutic potentiators to restore breast cancer drug resistance

Shuaishuai Xing, Yijun Liu, Huanfang Xie, Can Guo, Xiaolong Wang, Bingbing Lv, Xinyu Li, Jikuan Shao, Qinglong Guo, Feng Feng, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2024

特异性丁酰胆碱酯酶探针的研究进展

孙天雨，任欣予，肖行蒂，汪澜，白笑雪，孙昊鹏

《井冈山大学学报(自然科学版)》

2024

Small molecule-drug conjugates: Mechanistic insights and strategic design for enhanced cancer therapy

Jiawei Zhu, Yucheng Xiong, Xiaoxue Bai, Chenlong Xie, Baichen Xiong, Yao Chen, Haopeng Sun

Chinese Chemical Letters

DOI

2024

Advances in design strategies and imaging applications of specific butyrylcholinesterase probes

Tianyu Sun, Tianyu Sun, Zhoujun Dong, Paul Michael Malugulu, Tengfei Zhen, Lei Wang, Yao Chen, Haopeng Sun

Chinese Chemical Letters

DOI

2024

The design and development of LRRK2 inhibitors as novel therapeutics for Parkinson’s disease

Xiaoxue Bai, Jiawei Zhu, Yao Chen, Haopeng Sun

Future Medicinal Chemistry

DOI

2024

New insight into targeting the DNA damage response in the treatment of glioblastoma

Tengfei ZHEN, Tianyu Sun, Tianyu SUN, Baichen XIONG, Hui Liu, Lei Wang, Yao Chen, Haopeng Sun

Chinese Journal of Natural Medicines

DOI

2024

Optical control of butyrylcholinesterase (BChE) activity via photoswitchable azobenzene for potential treatment of Alzheimer’s disease

Lei Wang, Ziming Gao, Tianyu Sun, Tianyu Sun, Chen Chen, Chen Chen, Jiawei Zhu, Suyu Wang, Chen Yao, Haopeng Sun

Bioorganic Chemistry

DOI

2024

Can Targeted Protein Degradation Technology Provide a Potential Breakthrough in the Development of Anti-AD Drugs?

Baichen Xiong, Zuoaoyun Song, Leyan Wang, Ao Zhang, Yu Zhou, Na Zheng, Yuqing Wei, Yao Chen, Haopeng Sun

ACS Chemical Neuroscience

DOI

2024

NRF2 inhibitors: Recent progress, future design and therapeutic potential

Bingbing Lv, Shuaishuai Xing, Zhiqiang Wang, Ao Zhang, Qinjie Wang, Yaoyao Bian, Yuqiong Pei, Haopeng Sun, Yao Chen

European Journal of Medicinal Chemistry

DOI

2024

Structural modification strategies of triazoles in anticancer drug development

Qianwen Guan, Ziming Gao, Yuting Chen, Yuting Chen, Can Guo, Yao Chen, Yao Chen, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2024

New insights into butyrylcholinesterase: Pharmaceutical applications, selective inhibitors and multitarget-directed ligands

Tian‐Yu Sun, Tengfei Zhen, Chrisanta Hamis Harakandi, Lei Wang, Huanchao Guo, Yao Chen, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2024

Current therapy in amyotrophic lateral sclerosis (ALS): A review on past and future therapeutic strategies

Yuqing Wei, Sheng Zhong, Huajing Yang, Xueqing Wang, Bingbing Lv, Yaoyao Bian, Yuqiong Pei, Chunlei Xu, Qun Zhao, Wu Yulan, Daying Luo, Fan Wang, Haopeng Sun, Yao Chen

European Journal of Medicinal Chemistry

DOI

2024

Triazoles in Medicinal Chemistry: Physicochemical Properties, Bioisosterism, and Application

Qianwen Guan, Shuaishuai Xing, Lei Wang, Jiawei Zhu, Can Guo, Chunlei Xu, Qun Zhao, Yulan Wu, Yao Chen, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2024

Discovery of 4-benzylpiperazinequinoline BChE inhibitor that suppresses neuroinflammation for the treatment of Alzheimer's disease

Ying Chen, Weiting Zhang, Qi Li, Huanfang Xie, Shuaishuai Xing, Xin Lü, Weiping Lyu, Baichen Xiong, Yuanyuan Wang, Wei Qu, Wenyuan Liu, Heng Chi, Xiaolong Zhang, Feng Feng, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2024

Butyrylcholinesterase-Activated Near-Infrared Fluorogenic Probe for In Vivo Theranostics of Alzheimer’s Disease

Lei Wang, Tianyu Sun, Tengfei Zhen, Wei Li, Huajing Yang, Suyu Wang, Feng Feng, Yao Chen, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2024

Direct Synthesis of α- and β-2′-Deoxynucleosides with Stereodirecting Phosphine Oxide via Remote Participation

Xintong Tang, Yueer Zhou, Yingjie Wang, Yetong Lin, Shuheng Pan, Qianwei Che, Jinpeng Sang, Ziming Gao, Weiting Zhang, Yuanyuan Wang, Guolong Li, Longwei Gao, Zhimei Wang, Xudong Yang, Ao Liu, Suyu Wang, Biao Yu, Peng Hui Xu, Zhe Wang, Zhaolun Zhang, Peng Yang, Weijia Xie, Haopeng Sun, Wei Li

Journal of the American Chemical Society

DOI

2024

Discovery, Structure-Based Modification, In Vitro, In Vivo, and In Silico Exploration of m-Sulfamoyl Benzoamide Derivatives as Selective Butyrylcholinesterase Inhibitors for Treating Alzheimer’s Disease

Xin Lü, Yueqing Li, Qianwen Guan, Huajing Yang, Yijun Liu, Chenxi Du, Lei Wang, Qinghua Wang, Yuqiong Pei, Liang Wu, Haopeng Sun, Yao Chen

ACS Chemical Neuroscience

DOI

2024

Optimizing drug-like properties of selective butyrylcholinesterase inhibitors for cognitive improvement: Enhancing aqueous solubility by disrupting molecular plane

Shuaishuai Xing, Xu Tang, Leyan wang, Jun Wang, Bingbing Lv, Xiaolong Wang, Can Guo, Ye Zhao, Feng Feng, Wenyuan Liu, Yao Chen, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2024

Design, Synthesis, and Antitumor Activity Evaluation of Novel VISTA Small Molecule Inhibitors

Chengliang Sun, Yuling He, Gefei Wang, Guoyu Zhang, Yu Zhang, Hao Shen, Lingrong Hu, Yanze Sun, Binjian Jiang, Xiao Wang, Kai Yuan, Wenjian Min, Liping Wang, Haopeng Sun, Yibei Xiao, Peng Yang

Journal of Medicinal Chemistry

DOI

2023

丁酰胆碱酯酶在阿尔茨海默病中的作用及其抑制剂设计策略

邢帅帅，孙昊鹏

《药学进展》

2023

Identification of a Novel, Potent, and Orally Bioavailable Guanidine-Based SHP2 Allosteric Inhibitor from Virtual Screening and Rational Structural Optimization for the Treatment of KRAS Mutant Cancers

Qiangqiang Hou, Wenhua Jiang, Wenqiang Li, Chenyang Huang, Kexin Yang, Xiaoyu Chen, Mengchen Huang, Chengxia Shu, Guangmei Luo, Haopeng Sun, Qian Chu, Xiaoxing Wu

Journal of Medicinal Chemistry

DOI

2023

Inhibition of Son of Sevenless Homologue 1 (SOS1): Promising therapeutic treatment for KRAS-mutant cancers

Tingkai Chen, Xu Tang, Xu Tang, Feng Feng, Chunlei Xu, Qun Zhao, Yulan Wu, Haopeng Sun, Yao Chen

European Journal of Medicinal Chemistry

DOI

2023

Design, Synthesis, and Proof of Concept of Balanced Dual Inhibitors of Butyrylcholinesterase (BChE) and Histone Deacetylase 6 (HDAC6) for the Treatment of Alzheimer’s Disease

Lei Wang, Tian‐Yu Sun, Zhenqi Wang, Hui Liu, Weimin Qiu, Xu Tang, Huanchao Guo, Peng Yang, Chen Yao, Haopeng Sun

ACS Chemical Neuroscience

DOI

2023

The structural modification and biological evaluation of tetrahydrothienopyridine derivatives as selective BChE inhibitors

Tingkai Chen, Tingkai Chen, Shenghu Sang, Yuqing Wei, Yujie Ge, Jisheng Jin, Yaoyao Bian, Yuqiong Pei, Nian‐Guang Li, Haopeng Sun, Yao Chen

Bioorganic & Medicinal Chemistry Letters

DOI

2023

Development of Biaryl-Containing Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors for Reversing AKR1C3-Mediated Drug Resistance in Cancer Treatment

Siyu He, Xianglin Chu, Yujia Wu, Jiheng Jiang, Pengfei Fang, Yuting Chen, Yang Liu, Zhixia Qiu, Yibei Xiao, Zhiyu Li, Di Pan, Qian Zhang, Huanfang Xie, Shuaishuai Xing, Feng Feng, Wenyuan Liu, Qinglong Guo, Li Zhao, Peng Yang, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2023

Discovery of Potent and Wild-Type-Sparing Fourth-Generation EGFR Inhibitors for Treatment of Osimertinib-Resistance NSCLC

Haojie Dong, Xiuquan Ye, Yasheng Zhu, Hao Shen, Hongtao Shen, Weijiao Chen, Minghui Ji, Mingming Zheng, Keren Wang, Zeyu Cai, Haopeng Sun, Yibei Xiao, Peng Yang

Journal of Medicinal Chemistry

DOI

2023

Regulation of beta‐amyloid for the treatment of Alzheimer's disease: Research progress of therapeutic strategies and bioactive compounds

Weimin Qiu, Hui Liu, Yijun Liu, Xin Lü, Lei Wang, Yanyu Hu, Feng Feng, Qi Li, Haopeng Sun

Medicinal Research Reviews

DOI

2023

Design and Synthesis of Sulfonium Derivatives: A Novel Class of α-Glucosidase Inhibitors with Potent In Vivo Antihyperglycemic Activities

Lu Lu, Jingyi Chen, Wenxiang Tao, Zhimei Wang, Dan Liu, Jiahui Zhou, Xiaoxing Wu, Haopeng Sun, Wei Li, Genzoh Tanabe, Osamu Muraoka, Bo Zhao, Liang Wu, Weijia Xie

Journal of Medicinal Chemistry

DOI

2023

The Development and Design Strategy of Leucine-Rich Repeat Kinase 2 Inhibitors: Promising Therapeutic Agents for Parkinson’s Disease

Xu Tang, Shuaishuai Xing, Mingkang Ma, Ziwei Xu, Qianwen Guan, Yuting Chen, Yuting Chen, Feng Feng, Wenyuan Liu, Tingkai Chen, Yao Chen, Yao Chen, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2023

Editorial: Pharmaceutical insights into the triazoles: Recent advances

Xian‐Qing Deng, Haopeng Sun, Bahaa G. M. Youssif

Frontiers in Chemistry

DOI

2022

乙酰、丁酰胆碱酯酶双靶点抑制剂的设计、合成及活性评价

黄中威，田森，戴金莲，郭燕，孙昊鹏，刘宗亮

《烟台大学学报(自然科学与工程版)》

2022

基于FDA批准药物数据的新型胆碱酯酶抑制剂发现

周游，薛鑫，王磊，孙昊鹏

《西南大学学报(自然科学版)》

2022

The Role of Leukocyte Immunoglobulin-Like Receptors Focusing on the Therapeutic Implications of the Subfamily B2

Feng Feng, Haopeng Sun, Yanyu Hu, Xin Lü, Weimin Qiu, Hui Liu, Qinghua Wang, Yao Chen, Wenyuan Liu

Current Drug Targets

DOI

2022

Development of highly potent and specific AKR1C3 inhibitors to restore the chemosensitivity of drug-resistant breast cancer

Yang Liu, Yuting Chen, Jiheng Jiang, Xianglin Chu, Qinglong Guo, Li Zhao, Feng Feng, Wenyuan Liu, Xiaolong Zhang, Siyu He, Peng Yang, Pengfei Fang, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2022

Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease

Yuanyuan Wang, Baichen Xiong, Hongzhi Lin, Qi Li, Hongyu Yang, Yuting Qiao, Qihang Li, Ziwei Xu, Weiping Lyu, Wei Qu, Wenyuan Liu, Yao Chen, Feng Feng, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2022

Medicinal Prospects of Targeting Tyrosinase: A Feature Review

Yuanyuan Wang, Baichen Xiong, Shuaishuai Xing, Ying Chen, Qinghong Liao, Jun Mo, Yao Chen, Qi Li, Haopeng Sun

Current Medicinal Chemistry

DOI

2022

Design, synthesis, and biological evaluation of aromatic tertiary amine derivatives as selective butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease

Xin Lü, Nan Qin, Yijun Liu, Chenxi Du, Feng Feng, Wenyuan Liu, Yao Chen, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2022

N-Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer’s Disease

Chenxi Du, Lei Wang, Qianwen Guan, Hongyu Yang, Tingkai Chen, Yijun Liu, Qihang Li, Weiping Lyu, Xin Lü, Ying Chen, Ying Chen, Yang Liu, Hui Liu, Feng Feng, Wenyuan Liu, Zongliang Liu, Wei Li, Chen Yao, Chen Yao, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2022

Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance

Siyu He, Yang Liu, Xianglin Chu, Qi Li, Weiping Lyu, Yijun Liu, Shuaishuai Xing, Feng Feng, Wenyuan Liu, Qinglong Guo, Li Zhao, Haopeng Sun

ACS Medicinal Chemistry Letters

DOI

2022

AKR1C3 regulated by NRF2/MAFG complex promotes proliferation via stabilizing PARP1 in hepatocellular carcinoma

Di Pan, Wanwan Yang, Yao Zeng, Hongkun Qin, Yuting Xu, Yanping Gui, Xiangshan Fan, Geng Tian, Yujia Wu, Haopeng Sun, Yuting Ye, Shihe Yang, Jieying Zhou, Qinglong Guo, Li Zhao

Oncogene

DOI

2022

Direct Synthesis of 2,6‐Dideoxy‐β‐glycosides and β‐Rhamnosides with a Stereodirecting 2‐(Diphenylphosphinoyl)acetyl Group

Xianglai Liu, Yetong Lin, Wenyi Peng, Zhaolun Zhang, Longwei Gao, Yueer Zhou, Zhe Song, Yingjie Wang, Peng Hui Xu, Biao Yu, Haopeng Sun, Weijia Xie, Wei Li

Angewandte Chemie

DOI

2022

A highly effective and stable butyrylcholinesterase inhibitor with multi-faceted neuroprotection and cognition improvement

Qi Li, Baichen Xiong, Yuanyuan Wang, Weiping Lyu, Shuaishuai Xing, Ying Chen, Qinghong Liao, Siyu He, Feng Feng, Wenyuan Liu, Yao Chen, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2022

Discovery of Tryptophan‐tetrahydroisoquinoline Derivatives as Multifunctional Agents for Treatment of Alzheimer's Disease

Xin Lü, Yijun Liu, Nan Qin, Chenxi Du, Yanyu Hu, Yao Chen, Haopeng Sun

Chinese Journal of Chemistry

DOI

2022

More than a Leaving Group: N‐Phenyltrifluoroacetimidate as a Remote Directing Group for Highly α‐Selective 1,2‐cis Glycosylation

Xianglai Liu, Yingying Song, Ao Liu, Yueer Zhou, Qian Zhu, Yetong Lin, Huiyong Sun, Kaidi Zhu, Wei Liu, Ning Ding, Weijia Xie, Haopeng Sun, Biao Yu, Peng Hui Xu, Wei Li

Angewandte Chemie

DOI

2022

The Design and Optimization of Monomeric Multitarget Peptides for the Treatment of Multifactorial Diseases

Tingkai Chen, Tian‐Yu Sun, Yaoyao Bian, Yuqiong Pei, Feng Feng, Heng Chi, Yuan Li, Xu Tang, Shenghu Sang, Chenxi Du, Ying Chen, Ying Chen, Chen Yao, Chen Yao, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2022

A Practical and High‐Affinity Fluorescent Probe for Butyrylcholinesterase: A Good Strategy for Binding Affinity Characterization

Lei Wang, Chenxi Du, Hui Liu, Weimin Qiu, Xin Lü, Yanyu Hu, Yueqing Li, Tian‐Yu Sun, Yao Chen, Haopeng Sun

Chinese Journal of Chemistry

DOI

2021

Therapeutic strategies of glioblastoma (GBM): The current advances in the molecular targets and bioactive small molecule compounds

Hui Liu, Weimin Qiu, Tianyu Sun, Lei Wang, Chenxi Du, Yanyu Hu, Wenyuan Liu, Feng Feng, Chen Yao, Haopeng Sun

Acta Pharmaceutica Sinica B

DOI

2021

Discovery of Resorcinol-Based Polycyclic Structures as Tyrosinase Inhibitors for Treatment of Parkinson’s Disease

Qi Li, Jun Mo, Baichen Xiong, Qinghong Liao, Ying Chen, Yuanyuan Wang, Shuaishuai Xing, Siyu He, Weiping Lyu, Ning Zhang, Haopeng Sun

ACS Chemical Neuroscience

DOI

2021

2‐Diphenylphosphinoyl ‐acetyl as a Remote Directing Group for the Highly Stereoselective Synthesis of β‐Glycosides

Xianglai Liu, Yetong Lin, Ao Liu, Qianhui Sun, Huiyong Sun, Peng Hui Xu, Guolong Li, Yingying Song, Weijia Xie, Haopeng Sun, Biao Yu, Wei Li

Chinese Journal of Chemistry

DOI

2021

Overview of human 20 alpha-hydroxysteroid dehydrogenase (AKR1C1): Functions, regulation, and structural insights of inhibitors

Xianglin Chu, Siyu He, Yang Liu, Yijun Liu, Feng Feng, Qinglong Guo, Li Zhao, Haopeng Sun

Chemico-Biological Interactions

DOI

2021

Strategies for Structural Modification of Small Molecules to Improve Blood–Brain Barrier Penetration: A Recent Perspective

Baichen Xiong, Yuanyuan Wang, Ying Chen, Shuaishuai Xing, Qinghong Liao, Yao Chen, Qi Li, Wei Li, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2021

Novel diosgenin-1,4-quinone hybrids: Synthesis, antitumor evaluation, and mechanism studies

Guolong Li, Qi Li, Haopeng Sun, Wei Li

The Journal of Steroid Biochemistry and Molecular Biology

DOI

2021

Computational design of binder as the LC3-p62 protein‐protein interaction

Weiping Lyu, Qihang Li, Yingming Wang, Chenxi Du, Feng Feng, Heng Chi, Yuan Li, Wenyuan Liu, Haopeng Sun

Bioorganic Chemistry

DOI

2021

Design, Bio‐evaluation and Molecular Dynamics Simulation of Novel GSK‐3β Inhibitors

Weiping Lyu, Qihang Li, Qi Li, Ying Chen, Yingming Wang, Tongzhong Tang, Feng Feng, Heng Chi, Yuan Li, Wenyuan Liu, Haopeng Sun

Molecular Informatics

DOI

2021

Highly Potent and Selective Butyrylcholinesterase Inhibitors for Cognitive Improvement and Neuroprotection

Qi Li, Ying Chen, Ying Chen, Shuaishuai Xing, Qinghong Liao, Baichen Xiong, Yuanyuan Wang, Weixuan Lu, Siyu He, Feng Feng, Wenyuan Liu, Yao Chen, Yao Chen, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2021

Synthesis and Activity of Miconazole Derivatives as Dual BChE/IDO1 Inhibitors for the Treatment of Alzheimer's Disease

Xin Lü, Yijun Liu, Nan Qin, Hongyu Yang, Yuting Qiao, Xueyang Jiang, Yao Chen, Feng Feng, Wenyuan Liu, You Zhou, Haopeng Sun

Future Medicinal Chemistry

DOI

2021

Achieving Effective and Selective CK1 Inhibitors Through Structure Modification

Chenxi Du, Hongyu Yang, Feng Feng, Wenyuan Liu, Yao Chen, Haopeng Sun

Future Medicinal Chemistry

DOI

2021

In Silico Approaches Using Pharmacophore Model Combined With Molecular Docking for Discovery of Novel ULK1 Inhibitors

Siyu He, Yang Liu, Qihang Li, Weiping Lyu, Feng Feng, Qinglong Guo, Li Zhao, Haopeng Sun

Future Medicinal Chemistry

DOI

2020

Degradation of proteins by PROTACs and other strategies

Yang Wang, Xueyang Jiang, Feng Feng, Wenyuan Liu, Haopeng Sun

Acta Pharmaceutica Sinica B

2020

STING, a promising target for small molecular immune modulator: A review

Yijun Liu, Xin Lü, Nan Qin, Yuting Qiao, Shuaishuai Xing, Wenyuan Liu, Feng Feng, Zongliang Liu, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2020

Synthesis and bio-evaluation of a novel selective butyrylcholinesterase inhibitor discovered through structure-based virtual screening

Shuaishuai Xing, Ying Chen, Baichen Xiong, Weixuan Lu, Qi Li, Yuanyuan Wang, Mengxia Jiao, Feng Feng, Yao Chen, Wenyuan Liu, Haopeng Sun

International Journal of Biological Macromolecules

DOI

2020

Recent research progress of Uncaria spp. based on alkaloids: phytochemistry, pharmacology and structural chemistry

Nan Qin, Xin Lü, Yijun Liu, Yuting Qiao, Wei Qu, Feng Feng, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2020

Discovery and Biological Evaluation of a Novel Highly Potent Selective Butyrylcholinsterase Inhibitor

Qi Li, Shuaishuai Xing, Ying Chen, Ying Chen, Qinghong Liao, Baichen Xiong, Siyu He, Weixuan Lu, Yang Liu, Hongyu Yang, Qihang Li, Feng Feng, Wenyuan Liu, Yao Chen, Yao Chen, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2020

Overview of AKR1C3: Inhibitor Achievements and Disease Insights

Yang Liu, Siyu He, Ying Chen, Yijun Liu, Feng Feng, Wenyuan Liu, Qinglong Guo, Li Zhao, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2020

p62/SQSTM1, a Central but Unexploited Target: Advances in Its Physiological/Pathogenic Functions and Small Molecular Modulators

Ying Chen, Qi Li, Qihang Li, Shuaishuai Xing, Yang Liu, Yijun Liu, Yao Chen, Wenyuan Liu, Feng Feng, Haopeng Sun

Journal of Medicinal Chemistry

DOI

2020

Discovery of a Selective 6-Hydroxy-1, 4-Diazepan-2-one Containing Butyrylcholinesterase Inhibitor by Virtual Screening and MM-GBSA Rescoring

You Zhou, Yanyu Hu, Xin Lü, Hongyu Yang, Qihang Li, Chenxi Du, Yao Chen, Kwon Ho Hong, Haopeng Sun

Dose-Response

DOI

2020

Design, Synthesis, and Evaluation of Acetylcholinesterase and Butyrylcholinesterase Dual-Target Inhibitors against Alzheimer’s Diseases

Yan Guo, Hongyu Yang, Zhongwei Huang, Sen Tian, Qihang Li, Chenxi Du, Tingkai Chen, Yang Liu, Haopeng Sun, Zongliang Liu

Molecules

DOI

2020

Small Molecular Nrf2 Inhibitors as Chemosensitizers for Cancer Therapy

Hongzhi Lin, Yuting Qiao, Hongyu Yang, Qin Nan, Wei Qu, Feng Feng, Wenyuan Liu, Yao Chen, Haopeng Sun

Future Medicinal Chemistry

DOI

2020

Targeted degradation of anaplastic lymphoma kinase by gold nanoparticle-based multi-headed proteolysis targeting chimeras

Yingming Wang, Lingfei Han, Fulei Liu, Fubai Yang, Xueyang Jiang, Haopeng Sun, Feng Feng, Jingwei Xue, Wenyuan Liu

Colloids and Surfaces B Biointerfaces

DOI

2019

干预肿瘤代谢的新策略:氨基酸代谢的调控途径及其药物研究进展

姜洪丽，蒋学阳，汤同中，柳文媛，冯锋，孙昊鹏，曲玮

《药学学报》

DOI

2019

Design, synthesis, in vitro and in vivo evaluation of benzylpiperidine-linked 1,3-dimethylbenzimidazolinones as cholinesterase inhibitors against Alzheimer’s disease

Jun Mo, Tingkai Chen, Hongyu Yang, Yan Guo, Qi Li, Yuting Qiao, Hongzhi Lin, Feng Feng, Wenyuan Liu, Yao Chen, Zongliang Liu, Haopeng Sun

Journal of Enzyme Inhibition and Medicinal Chemistry

DOI

2019

Reasonably activating Nrf2: A long-term, effective and controllable strategy for neurodegenerative diseases

Qi Li, Shuaishuai Xing, Ying Chen, Qinghong Liao, Qihang Li, Yang Liu, Siyu He, Feng Feng, Yao Chen, Jie Zhang, Wenyuan Liu, Qinglong Guo, Yuan Sun, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2019

Design, synthesis, biological evaluation, and molecular modeling studies of quinoline-ferulic acid hybrids as cholinesterase inhibitors

Jun Mo, Hongyu Yang, Tingkai Chen, Qihang Li, Hongzhi Lin, Feng Feng, Wenyuan Liu, Wei Qu, Qinglong Guo, Heng Chi, Yao Chen, Haopeng Sun

Bioorganic Chemistry

DOI

2019

Discovery, molecular dynamic simulation and biological evaluation of structurally diverse cholinesterase inhibitors with new scaffold through shape-based pharmacophore virtual screening

Hongyu Yang, Chenxi Du, Qihang Li, Tingkai Chen, Xin Lü, Qi Li, Feng Feng, Yao Chen, Wenyuan Liu, Haopeng Sun

Bioorganic Chemistry

DOI

2019

Small molecule modulators targeting protein kinase CK1 and CK2

Yuting Qiao, Tingkai Chen, Hongyu Yang, Yao Chen, Hongzhi Lin, Wei Qu, Feng Feng, Wenyuan Liu, Qinglong Guo, Zongliang Liu, Haopeng Sun

European Journal of Medicinal Chemistry

DOI

2019

Characterization, quantitation, similarity evaluation and combination with Na+,K+-ATPase of cardiac glycosides from Streblus asper

Yidan Bai, Wanfang Zhu, Yunhui Xu, Zijian Xie, Toshihiro Akihisa, Jiradej Manosroi, Haopeng Sun, Feng Feng, Wenyuan Liu, Jie Zhang

Bioorganic Chemistry

DOI

2018

多靶点药物设计策略及其研究进展

周俊廷，蒋学阳，冯锋，孙昊鹏

《药学学报》

2018

A facile and efficient [4 + 2] annulation reaction of sulfur ylides: access to N-fused benzimidazoles

Hui Qin, Yuanyuan Miao, Jian Xu, Qirui Bi, Wei Qu, Wenyuan Liu, Feng Feng, Haopeng Sun

Organic Chemistry Frontiers

DOI

2017

共价修饰类药物的研究进展

何思雨，孙昊鹏

《中国药科大学学报》

2017

Discovery of new acetylcholinesterase and butyrylcholinesterase inhibitors through structure-based virtual screening

Yao Chen, Hongzhi Lin, Hongyu Yang, Ren Xiang Tan, Yaoyao Bian, Tingming Fu, Wei Li, Liang Wu, Yuqiong Pei, Haopeng Sun

RSC Advances

DOI

2017

Design, synthesis, in vitro and in vivo evaluation of tacrine–cinnamic acid hybrids as multi-target acetyl- and butyrylcholinesterase inhibitors against Alzheimer's disease

Yao Chen, Hongzhi Lin, Jie Zhu, Kai Gu, Qi Li, Siyu He, Xin Lü, Ren Xiang Tan, Yuqiong Pei, Liang Wu, Yaoyao Bian, Haopeng Sun

RSC Advances

DOI

2015

靶向Hsp90-Cdc37蛋白-蛋白相互作用小分子抑制剂的研究进展

刘芳，孙昊鹏，尤启冬

《中国药科大学学报》

2015

Novel 5-carboxy-8-HQ based histone demethylase JMJD2A inhibitors: Introduction of an additional carboxyl group at the C-2 position of quinoline

Taotao Feng, Dong‐Dong Li, Hai Wang, Jian Zhuang, Fang Liu, Qichao Bao, Yonghua Lei, Weilin Chen, Xiaojin Zhang, Xiaoli Xu, Haopeng Sun, Qidong You, Xiaoke Guo

European Journal of Medicinal Chemistry

DOI

2015

Synthesis and evaluation of (±)-dunnione and its ortho-quinone analogues as substrates for NAD(P)H:quinone oxidoreductase 1 (NQO1)

Jinlei Bian, Lili Xu, Bang Deng, Qian Xue, Jun Yan Fan, Xiuwen Yang, Fang Liu, Xiaoli Xu, Xiaoke Guo, Xiang Li, Haopeng Sun, Qidong You, Xiaojin Zhang

Bioorganic & Medicinal Chemistry Letters

DOI

2015

Discovery of new scaffolds from approved drugs as acetylcholinesterase inhibitors

Yao Chen, Xiaoli Xu, Tingming Fu, Wei Li, Zongliang Liu, Haopeng Sun

RSC Advances

DOI

2015

Discovery of NAD(P)H:quinone oxidoreductase 1 (NQO1) inhibitors with novel chemical scaffolds by shape-based virtual screening combined with cascade docking

Jinlei Bian, Qian Xue, Bang Deng, Xiaoli Xu, Xiaoke Guo, Yalou Wang, Xiang Li, Haopeng Sun, Qidong You, Xiaojin Zhang

RSC Advances

DOI

2015

Identification of novel JMJD2A inhibitor scaffold using shape and electrostatic similarity search combined with docking method and MM-GBSA approach

Taotao Feng, Weilin Chen, Dong‐Dong Li, Hongzhi Lin, Fang Liu, Qichao Bao, Yonghua Lei, Xiaojin Zhang, Xiaoli Xu, Xiaoke Guo, Qidong You, Haopeng Sun

RSC Advances

DOI

2014

类天然藤黄属桥环呫吨酮的结构优化研究进展

王艳艳，张晓进，杨英睿，孙昊鹏，尤启冬

《药学学报》

2014

新型多靶向他克林衍生物的研究进展

陈瑶，孙昊鹏，李伟

《药学进展》

2014

Discovery of novel covalent proteasome inhibitors through a combination of pharmacophore screening, covalent docking, and molecular dynamics simulations

Aibo Li, Haopeng Sun, Lei Du, Xiaoxin Wu, Jianqin Cao, Qidong You, Yuyan Li

Journal of Molecular Modeling

DOI

2014

Microwave-assisted transition-metal-free intramolecular Ullmann-type O-arylation in water for the synthesis of xanthones and azaxanthones

Xiaojin Zhang, Li Yang, Yue Wu, Jianyao Du, Yingle Mao, Xiao Wang, Shijie Luan, Yonghua Lei, Xiang Li, Haopeng Sun, Qidong You

Tetrahedron Letters

DOI

2014

2-Substituted 3-methylnaphtho[1,2-b]furan-4,5-diones as novel L-shaped ortho-quinone substrates for NAD(P)H:quinone oxidoreductase (NQO1)

Jinlei Bian, Bang Deng, Lili Xu, Xiaoli Xu, Nan Wang, Tianhan Hu, Zeyu Yao, Jianyao Du, Li Yang, Yonghua Lei, Xiang Li, Haopeng Sun, Xiaojin Zhang, Qidong You

European Journal of Medicinal Chemistry

DOI

2014

Lewis acid mediated highly regioselective intramolecular cyclization for the synthesis of β-lapachone

Jinlei Bian, Bang Deng, Xiaojin Zhang, Tianhan Hu, Nan Wang, Wéi Wang, Haixiang Pei, Yu Fu Xu, Hongxi Chu, Xiang Li, Haopeng Sun, Qidong You

Tetrahedron Letters

DOI

2013

具有抗肿瘤活性的茚并异喹啉类化合物研究进展

张圣淼，孙昊鹏，贾剑敏，徐晓莉，尤启冬

《中国药科大学学报》

2013

CYP1A2抑制剂预测模型的建立及评价

李曼华，孙昊鹏，尤启冬

《中国药科大学学报》

2013

逆转肿瘤耐药的P-糖蛋白抑制剂研发新策略

李乾，江杰炜，张生烈，张晓进，孙昊鹏，尤启冬

《药学进展》

2013

组蛋白去甲基化酶JMJD及其抑制剂的研究进展

王海，冯涛涛，孙昊鹏，尤启冬

《药学进展》

2013

Design and bio-evaluation of indole derivatives as potent Kv1.5 inhibitors

Xiaoke Guo, Qian Yang, Jing Xu, Li Zhang, Hongxi Chu, Peng Yu, Yingying Zhu, Jinglian Wei, Weilin Chen, Yaozhong Zhang, Xiaojin Zhang, Haopeng Sun, Yiqun Tang, Qidong You

Bioorganic & Medicinal Chemistry

DOI

2013

Discovery and Design of Tricyclic Scaffolds as Protein Kinase CK2 (CK2) Inhibitors through a Combination of Shape-Based Virtual Screening and Structure-Based Molecular Modification

Haopeng Sun, Xiaoli Xu, Xiaowen Wu, Xiaojin Zhang, Fang Liu, Jianmin Jia, Xiaoke Guo, Jingjie Huang, Zhengyu Jiang, Taotao Feng, Hongxi Chu, You Zhou, Shenglie Zhang, Zongliang Liu, Qidong You

Journal of Chemical Information and Modeling

DOI

2013

Novel N-hydroxyfurylacrylamide-based histone deacetylase (HDAC) inhibitors with branched CAP group (Part 2)

Taotao Feng, Hai Wang, Hong Lin Su, Hui Lu, Li‐Qin Yu, Xiaojin Zhang, Haopeng Sun, Qidong You

Bioorganic & Medicinal Chemistry

DOI

2013

Novel approach to stereoselective synthesis of (E)/(Z)-(N-acyl-oxazolidinone)-eneglycinates

Yanyan Zhang, Haopeng Sun, Qidong You

Research on Chemical Intermediates

DOI

2013

Synthesis, cytotoxicity and topoisomerase II inhibitory activity of lomefloxacin derivatives

You Lang Zhou, Xiaoli Xu, Yuan Sun, Huaping Wang, Haopeng Sun, Qidong You

Bioorganic & Medicinal Chemistry Letters

DOI

2012

藤黄酸衍生物的合成及抗肿瘤活性研究

张生烈，李乾，张磊，孙昊鹏，尤启冬

《有机化学》

2012

Garcinia Xanthones as Orally Active Antitumor Agents

Xiaojin Zhang, Xiang Li, Haopeng Sun, Xiaojian Wang, Li Zhao, Yuan Gao, Xiaorong Liu, Shenglie Zhang, Yanyan Wang, Yingrui Yang, Su Zeng, Qinglong Guo, Qidong You

Journal of Medicinal Chemistry

DOI

2012

Synthesis and Anti‐tumor Evaluation of Novel C‐37 Modified Derivatives of Gambogic Acid

Xiang Li, Xiaojin Zhang, Haopeng Sun, Lei Zhang, Yuan Gao, Jinxin Wang, Qinglong Guo, Qidong You

Chinese Journal of Chemistry

DOI

2012

Studies on gambogic acid (IV): Exploring structure–activity relationship with IκB kinase-beta (IKKβ)

Haopeng Sun, Feihong Chen, Xiaojian Wang, Zongliang Liu, Qian Yang, Xiaojin Zhang, Jia Zhu, Lei Qiang, Qinglong Guo, Qidong You

European Journal of Medicinal Chemistry

DOI

2012

Synthesis and evaluation of novel aza-caged Garcinia xanthones

Xiaojin Zhang, Xiang Li, Haopeng Sun, Zhengyu Jiang, Lei Tao, Yuan Gao, Qinglong Guo, Qidong You

Organic & Biomolecular Chemistry

DOI

会议论文

2013

从炎癌转化过程中发现关键调控节点并针对其关键位点设计小分子调控剂

孙昊鹏

《2013年全国药物化学学术会议暨第四届中英药物化学学术会议》

2012

Indenoisoquinoline derivatives as topoisomerase I inhibitors that suppress angiogenesis by affecting the HIF signaling pathway

Xiaoli Xu, Shengmiao Zhang, Jianmin Jia, Haopeng Sun, Li Zhiyu, Yong Yang, Qidong You

《2012长三角药物化学研讨会论文集》

2012

基于药效团模型的新型ABCB1抑制剂设计以及生物活性评价

张生烈，魏寅祥，李乾，孙昊鹏，彭晖，尤启冬

《2012年中国药学大会暨第十二届中国药师周》

2011

基于天然产物的创新药物研究

孙昊鹏，郭青龙，尤启冬

《2011年全国药物化学学术会议——药物的源头创新论文摘要集》

预印本

2026

Choosing among Competing Pockets in Oligomeric Proteins: An OIPS-Assisted, Traceable Multi-Evidence Analysis

Chen Xiao, Yifan Zhu, Shilei Zhao, Xin Zhang, Sun HaoPeng, Yao Chen, Xin Xue

Research Square

DOI

2025

Design, Synthesis and Evaluation of Anti-Aβ Aggregation Activity of Lanosterol Derivatives

Haopeng Sun, Weiting Zhang, Baichen Xiong, Mingkang Ma, Jiawei Zhu, Yuanyuan Wang, Pilin Huang, Tengfei Zhen, Zuoaoyun Song, Hongtao Li, Chenyu Zhang, Suyu Wang, Chaojun Wang, Yue Wu, Wenyuan Liu

SSRN Electronic Journal

DOI

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