吴燕华｜复旦大学｜学者主页

2026

Identification of two novel NR5A1 variants in Chinese patients with premature ovarian insufficiency

Jinyi Dong, Yiqing Liu, Shuting Ren, Yi Luo, Jitong Mo, Dingling Guo, Xiaojin Zhang, Yanhua Wu

Gene Reports

DOI

2026

Expanding the Knowledge of the Genetic Spectrum of Primary Ovarian Insufficiency Using a Cohort of 118 Chinese Cases

Yuncheng Pan, Shuting Ren, Jitong Mo, Zixue Zhou, Yiqing Liu, Lang Zhou, Xiaojin Zhang, Yanhua Wu

Phenomics

DOI

2025

FANCL新突变（c.1033G>A）致早发性卵巢功能不全1例报道及体外功能验证

刘怡箐，任淑婷，潘韵程，张锋，张晓金，吴燕华

《复旦学报(医学版)》

2025

Genetic variants in HELB contribute to premature ovarian insufficiency and early age of natural menopause

Yuncheng Pan, Yuexin Yu, Jitong Mo, Shuting Ren, Zixue Zhou, Xi Yang, Yiqing Liu, Feng Zhang, Yanqin You, Xiaojin Zhang, Yanhua Wu

JCI Insight

DOI

2025

Identification of lncRNA expression profiles associated with ovarian development and ageing process in mice

Siyuan Chen, Zixue Zhou, Jitong Mo, Xi Yang, Yuncheng Pan, Renbin Liu, Muhammed Boye Jallow, Feng Zhang, Yanhua Wu

Journal of Applied Genetics

DOI

2024

Novel Loss-of-function Variants of ZP3 Associated with Premature Ovarian Insufficiency

Lang Zhou, Xi Yang, Shuting Ren, Yuncheng Pan, Zixue Zhou, Yiqing Liu, Jitong Mo, Feng Zhang, Xiaojin Zhang, Yanhua Wu

Reproductive Sciences

DOI

2024

Identification of Two Novel Missense Variants in BNC1 in Han Chinese Patients With Non‐syndromic Premature Ovarian Insufficiency

Yuncheng Pan, Jitong Mo, Shuting Ren, Yifei Zhang, Feng Zhang, Xiaojin Zhang, Yanhua Wu

Clinical Genetics

DOI

2024

Deleterious variants in RNF111 impair female fertility and induce premature ovarian insufficiency in humans and mice

Chengcheng Song, Yingying Qin, Yan Li, Bingyi Yang, Ting Guo, Wenqing Ma, Dian Xu, Keyan Xu, Fangfang Fu, Jin Li, Yanhua Wu, Shuyan Tang, Xiaojun Chen, Feng Zhang

Science China Life Sciences

DOI

2023

Rare variants in GPR3 in POI patients: a case series with review of literature

Shuting Ren, Feng Zhang, Lingyue Shang, Xi Yang, Yuncheng Pan, Xiaojin Zhang, Yanhua Wu

Journal of Ovarian Research

DOI

2023

Rare variants in FANCJ induce premature ovarian insufficiency in humans and mice

Xi Yang, Shuting Ren, Jialin Yang, Yuncheng Pan, Zixue Zhou, Qing Chen, Yunzheng Fang, Lingyue Shang, Feng Zhang, Xiaojin Zhang, Yanhua Wu

Journal of genetics and genomics/Journal of Genetics and Genomics

DOI

2023

Landscape of pathogenic mutations in premature ovarian insufficiency

Hanni Ke, Shuyan Tang, Ting Guo, Dong Hou, Xue Jiao, Shan Li, Wei Luo, Bingying Xu, Shidou Zhao, Guangyu Li, Xiaoxi Zhang, Shuhua Xu, Lingbo Wang, Yanhua Wu, Jiucun Wang, Feng Zhang, Yingying Qin, Jin Li, Zi‐Jiang Chen

Nature Medicine

DOI

2022

EIF4ENIF1 variants in two patients with non-syndromic premature ovarian insufficiency

Lingyue Shang, Shuting Ren, Xi Yang, Feng Zhang, Jin Li, Xiaojin Zhang, Yanhua Wu

European Journal of Medical Genetics

DOI

2022

HSD17B12 dosage insufficiency induced premature ovarian insufficiency in humans and mice

Qi‐Qi Wang, Qing Chen, Yixin Zhang, Xue Zhang, Chunyu Liu, Daqi Wang, Yanhua Wu, Yixi Sun, Ling Zhang, Chengcheng Song, Yongming Wang, Yanpeng An, Huiru Tang, Congjian Xu, Yanting Wu, Jin Li, Hefeng Huang, Feng Zhang

Clinical and Translational Medicine

DOI

2021

一例早发性卵巢功能不全患者的ATG7新发变异分析

尚凌月，杨熙，王颖忱，张锋，张晓金，吴燕华

《复旦学报(自然科学版)》

DOI

2021

Whole exome sequencing identified a rare WT1 loss‐of‐function variant in a non‐syndromic POI patient

Yingchen Wang, Qing Chen, Feng Zhang, Xi Yang, Lingyue Shang, Shuting Ren, Yuncheng Pan, Zixue Zhou, Guoqing Li, Yunzheng Fang, Jin Li, Yanhua Wu, Xiaojin Zhang

Molecular Genetics & Genomic Medicine

DOI

2021

Temporal transcriptomic landscape of postnatal mouse ovaries reveals dynamic gene signatures associated with ovarian aging

Zixue Zhou, Xi Yang, Yuncheng Pan, Lingyue Shang, Siyuan Chen, Jialin Yang, Jin Li, Feng Zhang, Yanhua Wu

Human Molecular Genetics

DOI

2021

Haploinsufficiency in non-homologous end joining factor 1 induces ovarian dysfunction in humans and mice

Guoqing Li, Xi Yang, Lingbo Wang, Yuncheng Pan, Siyuan Chen, Lingyue Shang, Yicheng Zhang, Yucheng Wu, Zixue Zhou, Qing Chen, Xue Zhang, Ling Zhang, Yingchen Wang, Jinsong Li, Jin Li, Yanhua Wu, Xiaojin Zhang, Feng Zhang

Journal of Medical Genetics

DOI

2020

“Response to the letter to the editor “Concerns regarding the potentially causal role of FANCA heterozygous variants in human primary ovarian insufficiency””

Xi Yang, Feng Zhang, Qinghua Shi, Yanhua Wu

Human Genetics

DOI

2020

A heterozygous hypomorphic mutation of Fanca causes impaired follicle development and subfertility in female mice

Yuncheng Pan, Xi Yang, Feng Zhang, Siyuan Chen, Zixue Zhou, Hao Yin, Hui Ma, Lingyue Shang, Jialin Yang, Guoqing Li, Yingchen Wang, Jin Li, Qinghua Shi, Yanhua Wu

Molecular Genetics and Genomics

DOI

2020

Rare deleterious BUB1B variants induce premature ovarian insufficiency and early menopause

Qing Chen, Hanni Ke, Xuezhen Luo, Lingbo Wang, Yanhua Wu, Shuyan Tang, Jinsong Li, Jin Li, Feng Zhang, Yingying Qin, Xiaojun Chen

Human Molecular Genetics

DOI

2019

Rare variants in FANCA induce premature ovarian insufficiency

Xi Yang, Xiaojin Zhang, Jiao Jiao, Feng Zhang, Yuncheng Pan, Qiqi Wang, Qing Chen, Baozhu Cai, Shuyan Tang, Zixue Zhou, Siyuan Chen, Hao Yin, Wei Fu, Yang Luo, Da Li, Guoqing Li, Lingyue Shang, Jia‐Ling Yang, Jin Li, Qinghua Shi, Yanhua Wu

Human Genetics

DOI

2019

Whole-exome sequencing reveals SALL4 variants in premature ovarian insufficiency: an update on genotype–phenotype correlations

Qiqi Wang, Da Li, Baozhu Cai, Qing Chen, Caihua Li, Yanhua Wu, Jin Li, Xiuxia Wang, Xiaojin Zhang, Feng Zhang

Human Genetics

DOI

吴燕华

精选作品

期刊论文

Identification of two novel NR5A1 variants in Chinese patients with premature ovarian insufficiency

Expanding the Knowledge of the Genetic Spectrum of Primary Ovarian Insufficiency Using a Cohort of 118 Chinese Cases

FANCL新突变（c.1033G>A）致早发性卵巢功能不全1例报道及体外功能验证

Genetic variants in HELB contribute to premature ovarian insufficiency and early age of natural menopause

Identification of lncRNA expression profiles associated with ovarian development and ageing process in mice

Novel Loss-of-function Variants of ZP3 Associated with Premature Ovarian Insufficiency

Identification of Two Novel Missense Variants in BNC1 in Han Chinese Patients With Non‐syndromic Premature Ovarian Insufficiency

Deleterious variants in RNF111 impair female fertility and induce premature ovarian insufficiency in humans and mice

Rare variants in GPR3 in POI patients: a case series with review of literature

Rare variants in FANCJ induce premature ovarian insufficiency in humans and mice

Landscape of pathogenic mutations in premature ovarian insufficiency

EIF4ENIF1 variants in two patients with non-syndromic premature ovarian insufficiency

HSD17B12 dosage insufficiency induced premature ovarian insufficiency in humans and mice

一例早发性卵巢功能不全患者的ATG7新发变异分析

Whole exome sequencing identified a rare WT1 loss‐of‐function variant in a non‐syndromic POI patient

Temporal transcriptomic landscape of postnatal mouse ovaries reveals dynamic gene signatures associated with ovarian aging

Haploinsufficiency in non-homologous end joining factor 1 induces ovarian dysfunction in humans and mice

“Response to the letter to the editor “Concerns regarding the potentially causal role of FANCA heterozygous variants in human primary ovarian insufficiency””

A heterozygous hypomorphic mutation of Fanca causes impaired follicle development and subfertility in female mice

Rare deleterious BUB1B variants induce premature ovarian insufficiency and early menopause

Rare variants in FANCA induce premature ovarian insufficiency

Whole-exome sequencing reveals SALL4 variants in premature ovarian insufficiency: an update on genotype–phenotype correlations

研究方向