Guan Wang, Xiwei Tian, Jianye Xia, Ju Chu, Siliang Zhang, Yingping Zhuang (2021). [New opportunities and challenges for hybrid data and model driven bioprocess optimization and scale-up]. PubMed.DOI
Ning Ding, Chao Li, Tao Wang, Meijin Guo, Ali Mohsin, Siliang Zhang (2020). Evaluation of an enclosed air-lift photobioreactor (ALPBR) for biomass and lipid biosynthesis of microalgal cells grown under fluid-induced shear stress. Biotechnology & Biotechnological Equipment.DOI
Zejian Wang, Xingzi Zhang, Ping Wang, Zhiwei Sui, Meijin Guo, Siliang Zhang, Yingping Zhuang (2020). Oxygen Uptake Rate Controlling Strategy Balanced with Oxygen Supply for Improving Coenzyme Q10 Production by Rhodobacter sphaeroides. Biotechnology and Bioprocess Engineering.DOI
Weilu Lin, Zejian Wang, Mingzhi Huang, Ju Chu, Yingping Zhuang, Siliang Zhang (2020). On stability analysis of cascaded linear time varying systems in dynamic isotope experiments. AIChE Journal.DOI
Gang Zhou, Xiwei Tian, Yumeng Lin, Siliang Zhang, Ju Chu (2019). Rational high-throughput system for screening of high sophorolipids-producing strains of Candida bombicola. Bioprocess and Biosystems Engineering.DOI
Weishan Wang, Shanshan Li, Zilong Li, Jingyu Zhang, Keqiang Fan, Gao‐Yi Tan, Guomin Ai, Sin Man Lam, Guanghou Shui, Zhiheng Yang, Hongzhong Lu, Pinjiao Jin, Yihong Li, Xiangyin Chen, Xuekui Xia, Xueting Liu, H. Kathleen Dannelly, Chen Yang, Yi An Yang, Siliang Zhang, Gil Alterovitz, Wensheng Xiang, Lixin Zhang (2019). Publisher Correction: Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces. Nature Biotechnology.DOI
Weishan Wang, Shanshan Li, Zilong Li, Jingyu Zhang, Keqiang Fan, Gao‐Yi Tan, Guomin Ai, Sin Man Lam, Guanghou Shui, Zhiheng Yang, Hongzhong Lu, Pinjiao Jin, Yihong Li, Xiangyin Chen, Xuekui Xia, Xueting Liu, H. Kathleen Dannelly, Chen Yang, Yi An Yang, Siliang Zhang, Gil Alterovitz, Wensheng Xiang, Lixin Zhang (2019). Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces. Nature Biotechnology.DOI
Guan Wang, Cees Haringa, Wenjun Tang, Henk J. Noorman, Ju Chu, Yingping Zhuang, Siliang Zhang (2019). Coupled metabolic‐hydrodynamic modeling enabling rational scale‐up of industrial bioprocesses. Biotechnology and Bioengineering.DOI
Lu Zhang, Leshi Liu, Kefeng Wang, Lan Xu, Liming Zhou, Weishan Wang, Chuan Li, Zheng Xu, Tong Shi, Haihong Chen, Yuanhang Li, Hui Xu, Xiuliang Yang, Zhichun Zhu, Biqin Chen, Dan Li, Guanghuang Zhan, Siliang Zhang, Lixin Zhang, Gao‐Yi Tan (2019). Phosphate limitation increases coenzyme Q10 production in industrial Rhodobacter sphaeroides HY01. Synthetic and Systems Biotechnology.DOI
Chao Li, Xiaonuo Teng, Huadong Peng, Xiaoping Yi, Yingping Zhuang, Siliang Zhang, Jianye Xia (2019). Novel scale-up strategy based on three-dimensional shear space for animal cell culture. Chemical Engineering Science.DOI
Guangdong Duan, Lumei Ding, Dongsheng Wei, Hangcheng Zhou, Ju Chu, Siliang Zhang, Jiangchao Qian (2019). Screening endogenous signal peptides and protein folding factors to promote the secretory expression of heterologous proteins in Pichia pastoris. Journal of Biotechnology.DOI
Guan Wang, Xinxin Wang, Tong Wang, Walter M. van Gulik, Henk J. Noorman, Yingping Zhuang, Ju Chu, Siliang Zhang (2019). Comparative Fluxome and Metabolome Analysis of Formate as an Auxiliary Substrate for Penicillin Production in Glucose‐Limited Cultivation of Penicillium chrysogenum. Biotechnology Journal.DOI
Chao Li, Jiangtao Tian, Weifei Wang, Huadong Peng, Ming Zhang, Haifeng Hang, Siliang Zhang, Jianye Xia (2019). Numerical and experimental assessment of a miniature bioreactor equipped with a mechanical agitator and non‐invasive biosensors. Journal of Chemical Technology & Biotechnology.DOI
Ning Ding, Chao Li, Meijin Guo, Ali Mohsin, Siliang Zhang (2019). Numerical simulation of scaling-up an inverted frusto-conical shaking bioreactor with low shear stress for mammalian cell suspension culture. Cytotechnology.DOI
Guan Wang, Junfei Zhao, Xinxin Wang, Tong Wang, Yingping Zhuang, Ju Chu, Siliang Zhang, Henk J. Noorman (2019). Quantitative metabolomics and metabolic flux analysis reveal impact of altered trehalose metabolism on metabolic phenotypes of Penicillium chrysogenum in aerobic glucose-limited chemostats. Biochemical Engineering Journal.DOI
Weilu Lin, Haifeng Hang, Yingping Zhuang, Siliang Zhang (2018). Variable selection in partial least squares with the weighted variable contribution to the first singular value of the covariance matrix. Chemometrics and Intelligent Laboratory Systems.DOI
Hongzhong Lu, Weiqiang Cao, Xiaoyun Liu, Yufei Sui, Liming Ouyang, Jianye Xia, Mingzhi Huang, Yingping Zhuang, Siliang Zhang, Henk J. Noorman, Ju Chu (2018). Multi-omics integrative analysis with genome-scale metabolic model simulation reveals global cellular adaptation of Aspergillus niger under industrial enzyme production condition. Scientific Reports.DOI
Chao Li, Wei Shu, Shuai Wang, Peng Liu, Yingpping Zhuang, Siliang Zhang, Jianye Xia (2018). Dynamic metabolic response of Aspergillus niger to glucose perturbation: evidence of regulatory mechanism for reduced glucoamylase production. Journal of Biotechnology.DOI
Wei Zou, Xiao Hua Wang, Ali Mohsin, Xiwei Tian, Meijin Guo, Huamei Liu, Li Zhang, Siliang Zhang, Yingping Zhuang (2018). Effective utilization of wastewater for valuable validamycin A biosynthesis by Streptomyces hygroscopicus K2509 in plant-scale bioreactor. Bioresources and Bioprocessing.DOI
Xiwei Tian, Gang Zhou, Weifei Wang, Ming Zhang, Haifeng Hang, Ali Mohsin, Ju Chu, Yingping Zhuang, Siliang Zhang (2018). Application of 8-parallel micro-bioreactor system with non-invasive optical pH and DO biosensor in high-throughput screening of l-lactic acid producing strain. Bioresources and Bioprocessing.DOI
Guan Wang, Junfei Zhao, Cees Haringa, Wenjun Tang, Jianye Xia, Ju Chu, Yingping Zhuang, Siliang Zhang, Amit T. Deshmukh, Walter M. van Gulik, Joseph J. Heijnen, Henk J. Noorman (2018). Comparative performance of different scale‐down simulators of substrate gradients in Penicillium chrysogenum cultures: the need of a biological systems response analysis. Microbial Biotechnology.DOI
Xiwei Tian, Yonghong Wang, Ju Chu, Yingping Zhuang, Siliang Zhang (2017). Metabolite profiling coupled with metabolic flux analysis reveals physiological and metabolic impacts on Lactobacillus paracasei oxygen metabolism. Process Biochemistry.DOI
Wei Zou, Xiao-Hua Wang, Kuipu Zhang, Ali Mohsin, Meijin Guo, Huamei Liu, Li Zhang, Lan Li, Siliang Zhang, Yingping Zhuang (2017). Study on production enhancement of validamycin A using online capacitance measurement coupled with 1H NMR spectroscopy analysis in a plant-scale bioreactor. Process Biochemistry.DOI
Yufei Sui, Liming Ouyang, Ju Chu, Weiqiang Cao, Lifeng Liang, Yingping Zhuang, Shu Cheng, Henk Norrman, Siliang Zhang, Gengyun Zhang (2017). Global transcriptional response of Aspergillus niger in the process of glucoamylase fermentation. Bioresources and Bioprocessing.DOI
Guan Wang, Baofeng Wu, Junfei Zhao, Cees Haringa, Jianye Xia, Ju Chu, Yingping Zhuang, Siliang Zhang, Joseph J. Heijnen, Walter M. van Gulik, Amit T. Deshmukh, Henk J. Noorman (2017). Power input effects on degeneration in prolonged penicillin chemostat cultures: A systems analysis at flux, residual glucose, metabolite, and transcript levels. Biotechnology and Bioengineering.DOI
Han Mou, Ming Hong, Xiaoyun Liu, Min-Chao LI, Mingzhi Huang, Ju Chu, Yingping Zhuang, Siliang Zhang (2017). Accurate Determination of Isotopic Abundance of Intracellular Metabolites of Saccharopolysporaerythraea Based on Ultra Performance Liquid Chromatography-Triple Quadrupole Mass Spectrometry. Chinese Journal of Analytical Chemistry.DOI
Rui Ye, Mingzhi Huang, Hongzhong Lu, Jiangchao Qian, Weilu Lin, Ju Chu, Yingping Zhuang, Siliang Zhang (2017). Comprehensive reconstruction and evaluation of Pichia pastoris genome-scale metabolic model that accounts for 1243 ORFs. Bioresources and Bioprocessing.DOI
Ping Liu, Mingzhi Huang, Menglei Guo, Jiangchao Qian, Weilu Lin, Ju Chu, Yingping Zhuang, Siliang Zhang (2016). Combined 13C-assisted metabolomics and metabolic flux analysis reveals the impacts of glutamate on the central metabolism of high β-galactosidase-producing Pichia pastoris. Bioresources and Bioprocessing.DOI
Hongzhong Lu, Weiqiang Cao, Liming Ouyang, Jianye Xia, Mingzhi Huang, Ju Chu, Yingping Zhuang, Siliang Zhang, Henk J. Noorman (2016). Comprehensive reconstruction and in silico analysis of Aspergillus niger genome‐scale metabolic network model that accounts for 1210 ORFs. Biotechnology and Bioengineering.DOI
Yufei Sui, Liming Ouyang, Hongzhong Lu, Yingping Zhuang, Siliang Zhang (2016). [Progress in omics research of Aspergillus niger]. PubMed.DOI
Fei Lu, Chao Li, Zejian Wang, Wei Liang Zhao, Ju Chu, Yingping Zhuang, Siliang Zhang (2016). High efficiency cell-recycle continuous sodium gluconate production by Aspergillus niger using on-line physiological parameters association analysis to regulate feed rate rationally. Bioresource Technology.DOI
Yu Liu, Zejian Wang, Jianye Xia, Cees Haringa, Yaping Liu, Ju Chu, Yingping Zhuang, Siliang Zhang (2016). Application of EulerLagrange CFD for quantitative evaluating the effect of shear force on Carthamus tinctorius L. cell in a stirred tank bioreactor. Biochemical Engineering Journal.DOI
Yu Liu, Zejian Wang, JianWen Zhang, Jianye Xia, Ju Chu, Siliang Zhang, Yingping Zhuang (2016). Quantitative evaluation of the shear threshold on Carthamus tinctorius L. cell growth with computational fluid dynamics in shaken flask bioreactors. Biochemical Engineering Journal.DOI
Ming Hong, Mingzhi Huang, Ju Chu, Yingping Zhuang, Siliang Zhang (2016). Impacts of proline on the central metabolism of an industrial erythromycin-producing strain Saccharopolyspora erythraea via 13 C labeling experiments. Journal of Biotechnology.DOI
Menglei Guo, Xiaoyun Liu, Mingzhi Huang, Minchao Li, Ju Chu, Yingping Zhuang, Siliang Zhang (2016). 13C-assisted Ultra-High Performance Liquid Chromatography-Triple Quadrupole Mass Spectrometry Method for Precise Determination of Intracellular Metabolites in Pichia pastoris. Chinese Journal of Analytical Chemistry.DOI
Yu Liu, Zejian Wang, Lan Li, Xiaolin Cui, Ju Chu, Siliang Zhang, Yingping Zhuang (2016). On-line monitoring of the aggregate size distribution of Carthamus tinctorius L. cells with multi-frequency capacitance measurements. RSC Advances.DOI
Xiwei Tian, Yonghong Wang, Ju Chu, Yingping Zhuang, Siliang Zhang (2015). Enhanced l-lactic acid production in Lactobacillus paracasei by exogenous proline addition based on comparative metabolite profiling analysis. Applied Microbiology and Biotechnology.DOI
Xiwei Tian, Yonghong Wang, Ju Chu, Yingping Zhuang, Siliang Zhang (2015). Improvement of L‐lactic acid production with a two‐step OUR control strategy. Journal of Chemical Technology & Biotechnology.DOI
Xiwei Tian, Ning Zhang, Yi An Yang, Yonghong Wang, Ju Chu, Yingping Zhuang, Siliang Zhang (2015). The effect of redox environment on l -lactic acid production by Lactobacillus paracasei —A proof by genetically encoded in vivo NADH biosensor. Process Biochemistry.DOI
Hongzhong Lu, Xiaoyun Liu, Mingzhi Huang, Jianye Xia, Ju Chu, Yingping Zhuang, Siliang Zhang, Henk J. Noorman (2015). Integrated isotope-assisted metabolomics and 13C metabolic flux analysis reveals metabolic flux redistribution for high glucoamylase production by Aspergillus niger. Microbial Cell Factories.DOI
Zhiqiang Xiong, Meijin Guo, Ju Chu, Yingping Zhuang, Siliang Zhang (2015). On-line specific growth rate control for improving reduced glutathione production in Saccharomyces cerevisiae. Biotechnology and Bioprocess Engineering.DOI
Wenjun Tang, Ao Pan, Hongzhong Lu, Jianye Xia, Yingping Zhuang, Siliang Zhang, Ju Chu, Henk J. Noorman (2015). Improvement of glucoamylase production using axial impellers with low power consumption and homogeneous mass transfer. Biochemical Engineering Journal.DOI
Hongzhong Lu, Chao Li, Wenjun Tang, Zejian Wang, Jianye Xia, Siliang Zhang, Yingping Zhuang, Ju Chu, Henk J. Noorman (2014). Dependence of fungal characteristics on seed morphology and shear stress in bioreactors. Bioprocess and Biosystems Engineering.DOI
Yang Liu, Xiaoping Yi, Yingping Zhuang, Siliang Zhang (2014). Limitations in the process of transcription and translation inhibit recombinant human chorionic gonadotropin expression in CHO cells. Journal of Biotechnology.DOI
Fei Shi, Jun Tan, Ju Chu, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2014). A qualitative and quantitative high-throughput assay for screening of gluconate high-yield strains by Aspergillus niger. Journal of Microbiological Methods.DOI
Minchao Li, Mingzhi Huang, Yuwei Liu, Ju Chu, Yingping Zhuang, Siliang Zhang (2014). Accurate Determination of 13C Isotopic Abundance of Free Intracellular Amino acids with Low Concentration by GC-MS-Selective Ion Monitoring Method. Chinese Journal of Analytical Chemistry.DOI
Jun Tan, Ju Chu, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2014). High-throughput system for screening of Monascus purpureus high-yield strain in pigment production. Bioresources and Bioprocessing.DOI
Qiang Zhang, Yong Chen, Ming Hong, Yang Gao, Ju Chu, Yingping Zhuang, Siliang Zhang (2014). The dynamic regulation of nitrogen and phosphorus in the early phase of fermentation improves the erythromycin production by recombinant Saccharopolyspora erythraea strain. Bioresources and Bioprocessing.DOI
Xiaoqing Hu, Ju Chu, Siliang Zhang, Yingping Zhuang, Xin Wu, Huaxin Chen, Zhongyuan Lv, Zhongyi Yuan (2014). An alkaline pH control strategy for methionine adenosyltransferase production in Pichia pastoris fermentation. Biotechnology and Bioprocess Engineering.DOI
Yongsheng Nie, Mingzhi Huang, Junjie Lu, Jiangchao Qian, Weilu Lin, Ju Chu, Yingping Zhuang, Siliang Zhang (2014). Impacts of high β-galactosidase expression on central metabolism of recombinant Pichia pastoris GS115 using glucose as sole carbon source via 13C metabolic flux analysis. Journal of Biotechnology.DOI
Xiwei Tian, Yonghong Wang, Ju Chu, Yingping Zhuang, Siliang Zhang (2014). Oxygen transfer efficiency and environmental osmolarity response to neutralizing agents on l-lactic acid production efficiency by Lactobacillus paracasei. Process Biochemistry.DOI
Huan Tian, Meijin Guo, Yingping Zhuang, Ju Chu, Siliang Zhang (2014). Enhanced proliferation of bone marrow mesenchymal stem cells by co-culture with TM4 mouse Sertoli cells: involvement of the EGF/PI3K/AKT pathway. Molecular and Cellular Biochemistry.DOI
Jian-feng Wang, Hai-lin Meng, Zhiqiang Xiong, Siliang Zhang, Yong Wang (2014). Identification of novel knockout and up-regulated targets for improving isoprenoid production in E. coli. Biotechnology Letters.DOI
Xiwei Tian, Yonghong Wang, Ju Chu, Yingping Zhuang, Siliang Zhang (2014). l-Lactic acid production benefits from reduction of environmental osmotic stress through neutralizing agent combination. Bioprocess and Biosystems Engineering.DOI
Minghui Xie, Jianye Xia, Zhen Ping Zhou, Ju Chu, Yingping Zhuang, Siliang Zhang (2014). Flow Pattern, Mixing, Gas Hold-Up and Mass Transfer Coefficient of Triple-Impeller Configurations in Stirred Tank Bioreactors. Industrial & Engineering Chemistry Research.DOI
Lan Li, Zejian Wang, Xuejun Chen, Ju Chu, Yingping Zhuang, Siliang Zhang (2014). Optimization of polyhydroxyalkanoates fermentations with on-line capacitance measurement. Bioresource Technology.DOI
Guan Wang, Ju Chu, Henk J. Noorman, Jianye Xia, Wenjun Tang, Yingping Zhuang, Siliang Zhang (2014). Prelude to rational scale-up of penicillin production: a scale-down study. Applied Microbiology and Biotechnology.DOI
Xin-Xing Liu, Ping Li, Xiao-Feng Zhao, Yong-Hong Wang, Siliang Zhang (2013). [Rational screen of high kelimycin-producing strain by combined conventional mutagenesis and high-throughput screen method]. Wei sheng wu xue bao = Acta microbiologica Sinica.
Siliang Zhang (2013). Recent advances in bioreactor and its engineering. Shengwu jiagong guocheng.
Minghui Xie, Jianye Xia, Zhen Ping Zhou, Guo-zhong Zhou, Ju Chu, Yingping Zhuang, Siliang Zhang, Henk J. Noorman (2013). Power consumption, local and average volumetric mass transfer coefficient in multiple-impeller stirred bioreactors for xanthan gum solutions. Chemical Engineering Science.DOI
Xiaoqing Hu, Ju Chu, Siliang Zhang, Yingping Zhuang (2013). Comparative performance of S-adenosyl-l-methionine biosynthesis and degradation in Pichia pastoris using different promoters and novel consumption inhibitors. Enzyme and Microbial Technology.DOI
Jun Tan, Ju Chu, Yu-You Hao, Yonghong Wang, Sichao Yao, Yingping Zhuang, Siliang Zhang (2013). A high-throughput screening strategy for accurate quantification of erythromycin. Journal of the Taiwan Institute of Chemical Engineers.DOI
Pengwei Jin, Zhiqian Guo, Ju Chu, Jun Tan, Siliang Zhang, Weihong Zhu (2013). Screen-Printed Red Luminescent Copolymer Film Containing Cyclometalated Iridium(III) Complex as a High-Permeability Dissolved-Oxygen Sensor for Fermentation Bioprocess. Industrial & Engineering Chemistry Research.DOI
Pengwei Jin, Ju Chu, Miao Yu, Jun Tan, Siliang Zhang, Weihong Zhu (2013). A NIR luminescent copolymer based on platinum porphyrin as high permeable dissolved oxygen sensor for microbioreactors. AIChE Journal.DOI
Jing Han, Jing Hou, Fan Zhang, Guomin Ai, Ming Li, Shuangfeng Cai, Hailong Liu, Lei Wang, Zejian Wang, Siliang Zhang, Lei Cai, Dahe Zhao, Jian Bo Zhou, Hua Xiang (2013). Multiple Propionyl Coenzyme A-Supplying Pathways for Production of the Bioplastic Poly(3-Hydroxybutyrate- co -3-Hydroxyvalerate) in Haloferax mediterranei. Applied and Environmental Microbiology.DOI
Yong Chen, Zejian Wang, Ju Chu, Yingping Zhuang, Siliang Zhang, Xiaoguang Yu (2013). Significant decrease of broth viscosity and glucose consumption in erythromycin fermentation by dynamic regulation of ammonium sulfate and phosphate. Bioresource Technology.DOI
Lei Deng, Bingyang Shi, Yingping Zhuang, Ju Chu, Xiaolin Shi, Siliang Zhang, Meijin Guo (2013). Performance and Mechanism of Neuroleukin in the Growth and Survival of Sertoli Cell-Induced Neurons in a Coculture System. Cell Transplantation.DOI
Lang Zhou, Jiantao Kong, Yingping Zhuang, Ju Chu, Siliang Zhang, Meijin Guo (2013). Ex vivo expansion of bone marrow mesenchymal stem cells using microcarrier beads in a stirred bioreactor. Biotechnology and Bioprocess Engineering.DOI
Yong Chen, Mingzhi Huang, Zejian Wang, Ju Chu, Yingping Zhuang, Siliang Zhang (2013). Controlling the feed rate of glucose and propanol for the enhancement of erythromycin production and exploration of propanol metabolism fate by quantitative metabolic flux analysis. Bioprocess and Biosystems Engineering.DOI
Jun Tan, Ju Chu, Yu-You Hao, Yuanxin Guo, Yingping Zhuang, Siliang Zhang (2013). High-Throughput System for Screening of Cephalosporin C High-Yield Strain by 48-Deep-Well Microtiter Plates. Applied Biochemistry and Biotechnology.DOI
Taicheng Zhu, Haifeng Hang, Ju Chu, Yingping Zhuang, Siliang Zhang, Meijin Guo (2013). Transcriptional investigation of the effect of mixed feeding to identify the main cellular stresses on recombinant Pichia pastoris. Journal of Industrial Microbiology & Biotechnology.DOI
Yuanyuan Li, Yuan-Yuan Li, Xiao Chang, Wen‐Bang Yu, Hao Li, Hui Yu, Hui Yu, Bao-Hong Liu, Siliang Zhang, Siliang Zhang, Bang‐Ce Ye, Yixue Li, Yixue Li (2013). Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S. erythraea E3 and NRRL23338 strains. BMC Genomics.DOI
Mengxin Xie, Jianye Xia, G.‐Z. Zhou, Siliang Zhang, YU Pei-qing (2012). Hydrodynamics Characterization of an Ellipse Gate Impeller by Experimental and Numerical Studies. Chemical Engineering & Technology.DOI
Peng Yin, Youyuan Li, Jin Zhou, Yonghong Wang, Siliang Zhang, Bang‐Ce Ye, Wei-Feng Ge, Yuelan Xia (2012). Direct proteomic mapping of Streptomyces avermitilis wild and industrial strain and insights into avermectin production. Journal of Proteomics.DOI
Siliang Zhang (2012). Quantitative determination of fatty acids in cell membrane of Corynebacterium glutamicum during glutamic acid production by GC-MS. China Brewing.
Siliang Zhang (2012). Relationship of Oxygen Uptake Rate with the Growth and Metabolism of Hybridma Cells during a Fed-Batch Culture Process. Journal of Chemical Engineering of Chinese Universities.
Jun Tan, Ju Chu, Wenjuan Shi, Cheng Lin, Yuanxin Guo, Yingping Zhuang, Siliang Zhang, Tadayuki Imanaka (2012). High-throughput screening strategy used for enhanced production of pigment by Monascus purpureus D39-4. Food Science and Biotechnology.DOI
Ju Chu, Jiangchao Qian, Yingping Zhuang, Siliang Zhang, Yourong Li (2012). Progress in the research of S-adenosyl-l-methionine production. Applied Microbiology and Biotechnology.DOI
Chao Li, Jianye Xia, Ju Chu, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2012). CFD analysis of the turbulent flow in baffled shake flasks. Biochemical Engineering Journal.DOI
Lan Yu, Xiangyun Yan, Long Wang, Ju Chu, Yingping Zhuang, Siliang Zhang, Meijin Guo (2012). Molecular cloning and functional characterization of an ATP-binding cassette transporter OtrC from Streptomyces rimosus. BMC Biotechnology.DOI
Yiming Yang, Jianye Xia, Jianhua Li, Ju Chu, Liang Li, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2012). A novel impeller configuration to improve fungal physiology performance and energy conservation for cephalosporin C production. Journal of Biotechnology.DOI
Zhenyu Tang, Paul Herron, Iain S. Hunter, Siliang Zhang, Meijin Guo (2012). Insight into microevolution of Streptomyces rimosus based on analysis of zwf and rex genes. African Journal of Microbiology Research.DOI
Lan Yu, Nan Cao, Long Wang, Ciying Xiao, Meijin Guo, Ju Chu, Yingping Zhuang, Siliang Zhang (2012). Oxytetracycline biosynthesis improvement in Streptomyces rimosus following duplication of minimal PKS genes. Enzyme and Microbial Technology.DOI
Xiaoqing Ren, MA Li-zhen, Ju Chu, Yonghong Wang, Yingping Zhuang, Siliang Zhang, Hongshun Yang, Hongjie An (2012). Optimization of Enzymatic Hydrolysis of Channel Catfish Bones for Preparing Antimicrobial Agents. Journal of Aquatic Food Product Technology.DOI
Hà Văn Huân, Yong Wang, Siliang Zhang (2012). Down-Regulation of Pm4CL1 Gene Expression in E. coli Model by Antisense mRNA. Biochemical Genetics.DOI
Youyuan Li, Pei Hao, Siliang Zhang, Yixue Li (2011). Feature-matching Pattern-based Support Vector Machines for Robust Peptide Mass Fingerprinting. Molecular & Cellular Proteomics.DOI
Siliang Zhang (2011). Effects of Copy Number on Expression of Porcine Insulin Precursor (PIP) by Recombinant Pichia Pastoris. Chemistry & Bioengineering.
Siliang Zhang (2011). Determination of Coenzyme NAD~+ and NADH of Saccharomyces cerevisiae Cells in Ethanol Production. Journal of Food Science and Biotechnology.
Siliang Zhang (2011). Optimization of defined culture medium for L-lactic acid fermentation by Lactobacillus paracasei. Shengwu jiagong guocheng.
Xiang Zou, Jianye Xia, Ju Chu, Yingping Zhuang, Siliang Zhang (2011). Real-time fluid dynamics investigation and physiological response for erythromycin fermentation scale-up from 50 L to 132 m3 fermenter. Bioprocess and Biosystems Engineering.DOI
Dan Wu, Ju Chu, Yu-You Hao, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2011). Incomplete protein disulphide bond conformation and decreased protein expression result from high cell growth during heterologous protein expression in Pichia pastoris. Journal of Biotechnology.DOI
Xu Li, Zhenzhen Dai, Yonghong Wang, Siliang Zhang (2011). Enhancement of phototrophic hydrogen production by Rhodobacter sphaeroides ZX-5 using fed-batch operation based on ORP level. International Journal of Hydrogen Energy.DOI
Jiequn Wu, Qinglin Zhang, Wei Deng, Jiangchao Qian, Siliang Zhang, Wen Liu (2011). Toward Improvement of Erythromycin A Production in an IndustrialSaccharopolyspora erythraea Strain via Facilitation of Genetic Manipulation with an Artificial attB Site for Specific Recombination. Applied and Environmental Microbiology.DOI
Xu Li, Huan Shi, Yonghong Wang, Siliang Zhang, Ju Chu, Ming Zhang, Mingzhi Huang, Yingping Zhuang (2011). Effects of vitamins (nicotinic acid, vitamin B1 and biotin) on phototrophic hydrogen production by Rhodobacter sphaeroides ZX-5. International Journal of Hydrogen Energy.DOI
Dan Wu, Ju Chu, Yu-You Hao, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2011). High efficient production of recombinant human consensus interferon mutant in high cell density culture of Pichia pastoris using two phases methanol control. Process Biochemistry.DOI
Hailin Meng, Zhiguo Lu, Yong Wang, Xiao‐Ning Wang, Siliang Zhang (2011). In silico improvement of heterologous biosynthesis of erythromycin precursor 6-deoxyerythronolide B in Escherichia coli. Biotechnology and Bioprocess Engineering.DOI
Hà Văn Huân, Ho Van Giang, Yong Wang, Siliang Zhang (2011). Overexpression and the enzymatic properties of the recombinant 4-coumarate: coenzyme A ligase, a key enzyme in lignin biosynthesis pathway. Journal of the Indian Academy of Wood Science.DOI
Jianguang Liang, Xiaohe Chu, Zhiqiang Xiong, Ju Chu, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2011). Oxygen uptake rate regulation during cell growth phase for improving avermectin B1a batch fermentation on a pilot scale (2 m3). World Journal of Microbiology and Biotechnology.DOI
Xiulin Qin, Jiangchao Qian, Gaofeng Yao, Yingping Zhuang, Siliang Zhang, Ju Chu (2011). GAP Promoter Library for Fine-Tuning of Gene Expression in Pichia pastoris. Applied and Environmental Microbiology.DOI
Zhenyu Tang, Ciying Xiao, Yingping Zhuang, Ju Chu, Siliang Zhang, Paul Herron, Iain S. Hunter, Meijin Guo (2011). Improved oxytetracycline production in Streptomyces rimosus M4018 by metabolic engineering of the G6PDH gene in the pentose phosphate pathway. Enzyme and Microbial Technology.DOI
Hailin Meng, Yong Wang, Qiang Hua, Siliang Zhang, Xiao‐Ning Wang (2011). In silico analysis and experimental improvement of taxadiene heterologous biosynthesis in Escherichia coli. Biotechnology and Bioprocess Engineering.DOI
Suwen Hu, Lei Deng, Huamao Wang, Yingping Zhuang, Ju Chu, Siliang Zhang, Zhonghai Li, Meijin Guo (2011). Bioprocess development for the production of mouse-human chimeric anti-epidermal growth factor receptor vIII antibody C12 by suspension culture of recombinant Chinese hamster ovary cells. Cytotechnology.DOI
Minghui Xie, Guo-zhong Zhou, Jianye Xia, Chen Zou, YU Pei-qing, Siliang Zhang (2011). Comparison of Power Number for Paddle-Type Impellers by Three Methods. JOURNAL OF CHEMICAL ENGINEERING OF JAPAN.DOI
Siliang Zhang (2010). Effects of Carbon Dioxide on Cell Growth and Vitamin B_(12) Production in Pseudomonas Denitrificans. Huadong Li-Gong Daxue xuebao.
Xiang Zou, Wei Zeng, Chen Chang-fa, Xia-chang Qi, Jiangchao Qian, Ju Chu, Yingping Zhuang, Siliang Zhang, Wanjun Li (2010). Fermentation optimization and industrialization of recombinant Saccharopolyspora erythraea strains for improved erythromycin a production. Biotechnology and Bioprocess Engineering.DOI
Hà Văn Huân, Ho Van Giang, Ngo Van Thanh, Siliang Zhang, Yong Wang (2010). Identification and functional analysis of the Pm4CL1 gene in transgenic tobacco plant as the basis for regulating lignin biosynthesis in forest trees. Molecular Breeding.DOI
Xiang Zou, Wan-jun Li, Wei Zeng, Ju Chu, Yingping Zhuang, Siliang Zhang (2010). An assessment of seed quality on erythromycin production by recombinant Saccharopolyspora erythraea strain. Bioresource Technology.DOI
Dan Wu, Ju Chu, Yu-You Hao, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2010). Influence of Specific Growth Rate on Specific Productivity and Intermolecular disulfide bond of Recombinant Protein Produced by a Pichia pastoris Mut+ Strain. Journal of Biotechnology.DOI
Dan Wu, Ju Chu, Yu-You Hao, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2010). Methanol Induction Optimization for Recombinant Human Consensus Interferon Mutant Production in Pichia pastoris. Journal of Biotechnology.DOI
Taicheng Zhu, Meijin Guo, Yingping Zhuang, Ju Chu, Siliang Zhang (2010). Understanding the effect of foreign gene dosage on the physiology of Pichia pastoris by transcriptional analysis of key genes. Applied Microbiology and Biotechnology.DOI
Li Xu, Yonghong Wang, Siliang Zhang, Ju Chu, Ming Zhang, Mingzhi Huang, Yingping Zhuang (2010). Effects of light/dark cycle, mixing pattern and partial pressure of H2 on biohydrogen production by Rhodobacter sphaeroides ZX-5. Bioresource Technology.DOI
Jianhua Li, Yiming Yang, Ju Chu, Mingzhi Huang, Liang Li, Xiaochun Zhang, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2010). Quantitative metabolic flux analysis revealed uneconomical utilization of ATP and NADPH in Acremonium chrysogenum fed with soybean oil. Bioprocess and Biosystems Engineering.DOI
Ying Zhuo, Wenquan Zhang, Difei Chen, Hong Chao Gao, Jun Tao, Mei Liu, Zhongxuan Gou, Xianlong Zhou, Bang‐Ce Ye, Qing Zhang, Siliang Zhang, Lixin Zhang (2010). Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis. Proceedings of the National Academy of Sciences.DOI
Zhiqiang Xiong, Meijin Guo, Yuanxin Guo, Ju Chu, Yingping Zhuang, Nam Sun Wang, Siliang Zhang (2010). RQ feedback control for simultaneous improvement of GSH yield and GSH content in Saccharomyces cerevisiae T65. Enzyme and Microbial Technology.DOI
Siliang Zhang (2009). Analysis of Mass Isotopomer Distributions of Proteingenic Amino Acids Used GC-MS during ~(13)CMFA. Zhongguo shengwu gongcheng zazhi.
Zejian Wang, Huiyuan Wang, Yongliang Li, Ju Chu, Mingzhi Huang, Yingping Zhuang, Siliang Zhang (2009). Improved vitamin B12 production by step-wise reduction of oxygen uptake rate under dissolved oxygen limiting level during fermentation process. Bioresource Technology.DOI
Xu Li, Yonghong Wang, Siliang Zhang, Ju Chu, Zhang Ming, Mingzhi Huang, Yingping Zhuang (2009). Enhancement of phototrophic hydrogen production by Rhodobacter sphaeroides ZX-5 using a novel strategy — shaking and extra-light supplementation approach. International Journal of Hydrogen Energy.DOI
Zhenlin Li, Yonghong Wang, Ju Chu, Yingping Zhuang, Siliang Zhang (2009). Effect of branched-chain amino acids, valine, isoleucine and leucine on the biosythesis of bitespiramycin 4"-O-acylspiramycins. Brazilian Journal of Microbiology.DOI
Bang‐Ce Ye, Yan Zhang, Hui Yu, Wen‐Bang Yu, Baohong Liu, Bin‐Cheng Yin, Chun-Yun Yin, Yuanyuan Li, Ju Chu, Siliang Zhang (2009). Time-Resolved Transcriptome Analysis of Bacillus subtilis Responding to Valine, Glutamate, and Glutamine. PLoS ONE.DOI
Dan Wu, Dong Ma, Yu-You Hao, Ju Chu, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2009). Incomplete formation of intramolecular disulfide bond triggers degradation and aggregation of human consensus interferon-α mutant by Pichia pastoris. Applied Microbiology and Biotechnology.DOI
Yonghong Wang, Jin Zhou, Ju Chu, Jiangchao Qian, Siliang Zhang, Yingping Zhuang (2009). Production and distribution of β-glucosidase in a mutant strain Trichoderma viride T 100-14. New Biotechnology.DOI
Keliang Gao, Siliang Zhang, Dongzhi Wei (2009). Enhancement of Gluconobacter oxydans catalyzing D ‐lactic acid production by coupling of synthesis and separation. Journal of Chemical Technology & Biotechnology.DOI
Yong Wang, Ju Chu, Yingping Zhuang, Yonghong Wang, Jianye Xia, Siliang Zhang (2009). Industrial bioprocess control and optimization in the context of systems biotechnology. Biotechnology Advances.DOI
Yonghong Wang, C. P. Wu, Ju Chu, Yu-You Hao, Yingping Zhuang, Siliang Zhang (2009). Regulation of branched-chain amino acid catabolism: glucose limitation enhances the component of isovalerylspiramycin for the bitespiramycin production. Bioprocess and Biosystems Engineering.DOI
Hui Hu, Jiangchao Qian, Ju Chu, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2009). Optimization of l-methionine feeding strategy for improving S-adenosyl-l-methionine production by methionine adenosyltransferase overexpressed Pichia pastoris. Applied Microbiology and Biotechnology.DOI
Hui Hu, Jiangchao Qian, Ju Chu, Yong Wang, Yingping Zhuang, Siliang Zhang (2009). DNA shuffling of methionine adenosyltransferase gene leads to improved S-adenosyl-l-methionine production in Pichia pastoris. Journal of Biotechnology.DOI
Xiang Zou, Haifeng Hang, Ju Chu, Yingping Zhuang, Siliang Zhang (2009). Enhancement of erythromycin A production with feeding available nitrogen sources in erythromycin biosynthesis phase. Bioresource Technology.DOI
Bing-Quan Gou, Ju Chu, Siliang Zhang, Yonghong Wang, Yingping Zhuang, Hua Huang, Zhen Li, Zhongyi Yuan (2009). Production of penicillin G amidase from Alcaligenes faecalis in a recombinant Escherichia coli. Journal of the Taiwan Institute of Chemical Engineers.DOI
Taicheng Zhu, Meijin Guo, Chen Sun, Jiangchao Qian, Yingping Zhuang, Ju Chu, Siliang Zhang (2009). A systematical investigation on the genetic stability of multi-copy Pichia pastoris strains. Biotechnology Letters.DOI
Jin Zhou, Yonghong Wang, Ju Chu, Lingzhi Luo, Yingping Zhuang, Siliang Zhang (2008). Optimization of cellulase mixture for efficient hydrolysis of steam-exploded corn stover by statistically designed experiments. Bioresource Technology.DOI
Zhiqiang Xiong, Meijin Guo, Yuanxin Guo, Ju Chu, Yingping Zhuang, Siliang Zhang (2008). Efficient extraction of intracellular reduced glutathione from fermentation broth of Saccharomyces cerevisiae by ethanol. Bioresource Technology.DOI
Peng Yin, Yonghong Wang, Siliang Zhang, Ju Chu, Yingping Zhuang, Ning Chen, Xin‐Feng Li, Yanbin Wu (2008). Effect of mycelial morphology on bioreactor performance and avermectin production of Streptomyces avermitilis in submerged cultivations. Journal of The Chinese Institute of Chemical Engineers.DOI
Haifeng Hang, Wen Chen, Meijin Guo, Ju Chu, Yingping Zhuang, Siliang Zhang (2008). A simple unstructured model-based control for efficient expression of recombinant porcine insulin precursor by Pichia pastoris. Korean Journal of Chemical Engineering.DOI
Xiang Zou, Haifeng Hang, Chen Chang-fa, Ju Chu, Yingping Zhuang, Siliang Zhang (2008). Application of oxygen uptake rate and response surface methodology for erythromycin production by Saccharopolyspora erythraea. Journal of Industrial Microbiology & Biotechnology.DOI
Dan Wu, Yu-You Hao, Ju Chu, Yingping Zhuang, Siliang Zhang (2008). Inhibition of degradation and aggregation of recombinant human consensus interferon-α mutant expressed in Pichia pastoris with complex medium in bioreactor. Applied Microbiology and Biotechnology.DOI
Yifeng Lu, Yonghong Wang, XU Guo-qian, Ju Chu, Yingping Zhuang, Siliang Zhang (2008). Influence of High Solid Concentration on Enzymatic Hydrolysis and Fermentation of Steam-Exploded Corn Stover Biomass. Applied Biochemistry and Biotechnology.DOI
Lei Feng, Meijin Guo, Shuxiang Zhang, Ju Chu, Yingping Zhuang, Siliang Zhang (2008). Improvement in the suspension‐culture production of recombinant adeno‐associated virus–LacZ in HEK‐293 cells using polyethyleneimine–DNA complexes in combination with hypothermic treatment. Biotechnology and Applied Biochemistry.DOI
Yonghong Wang, Bing-xia Xi, Yu-You Hao, Mingzhi Huang, Siliang Zhang (2008). A combined strategy to simultaneously improve the component of isovalerylspiramycin in a bitespiramycin (4″-O-acylspiramycins) complex and its biological titre. Process Biochemistry.DOI
Kuntai Li, Donghong Liu, Yingping Zhuang, Yonghong Wang, Ju Chu, Siliang Zhang (2008). Influence of Zn2+, Co2+ and dimethylbenzimidazole on vitamin B12 biosynthesis by Pseudomonas denitrificans. World Journal of Microbiology and Biotechnology.DOI
Kuntai Li, Donghong Liu, Yongliang Li, Ju Chu, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2008). Improved large-scale production of vitamin B12 by Pseudomonas denitrificans with betaine feeding. Bioresource Technology.DOI
Xiaoqing Hu, Ju Chu, Zhuo Zhang, Siliang Zhang, Yingping Zhuang, Yonghong Wang, Meijin Guo, Hua-Xin Chen, Zhongyi Yuan (2008). Effects of different glycerol feeding strategies on S-adenosyl-l-methionine biosynthesis by PGAP-driven Pichia pastoris overexpressing methionine adenosyltransferase. Journal of Biotechnology.DOI
Zhiqiang Xiong, Meijin Guo, Yuanxin Guo, Ju Chu, Yingping Zhuang, Siliang Zhang (2008). Real-time viable-cell mass monitoring in high-cell-density fed-batch glutathione fermentation by Saccharomyces cerevisiae T65 in industrial complex medium. Journal of Bioscience and Bioengineering.DOI
Jin Zhou, Yonghong Wang, Ju Chu, Bing-Quan Gou, Yingping Zhuang, Siliang Zhang, Zhongyi Yuan (2008). Penicillin G acylase purification with the aid of high-throughput screening approach. Journal of The Chinese Institute of Chemical Engineers.DOI
Jin Zhou, Yonghong Wang, Ju Chu, Yingping Zhuang, Siliang Zhang, Peng Yin (2008). Identification and purification of the main components of cellulases from a mutant strain of Trichoderma viride T 100-14. Bioresource Technology.DOI
Kuntai Li, Donghong Liu, Ju Chu, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2008). An effective and simplified pH-stat control strategy for the industrial fermentation of vitamin B12 by Pseudomonas denitrificans. Bioprocess and Biosystems Engineering.DOI
Yong Wang, Yiguang Wang, Ju Chu, Yingping Zhuang, Lixin Zhang, Siliang Zhang (2008). Erratum to: Improved production of erythromycin A by expression of a heterologous gene encoding S-adenosylmethionine synthetase. Applied Microbiology and Biotechnology.DOI
Peng Yin, Yonghong Wang, Siliang Zhang, Ju Chu, Yingping Zhuang, Mei-Long Wang, Jin Zhou (2008). Isolation of soluble proteins from an industrial strain Streptomyces avermitilis in complex culture medium for two-dimensional gel electrophoresis. Journal of Microbiological Methods.DOI
Jie Zhao, Yonghong Wang, Ju Chu, Siliang Zhang, Yingping Zhuang, Zhongyi Yuan (2008). Statistical optimization of medium for the production of pyruvate oxidase by the recombinant Escherichia coli. Journal of Industrial Microbiology & Biotechnology.DOI
Yun Chen, Wei Deng, Jiequn Wu, Jiangchao Qian, Ju Chu, Yingping Zhuang, Siliang Zhang, Wen Liu (2008). Genetic Modulation of the Overexpression of Tailoring Genes eryK and eryG Leading to the Improvement of Erythromycin A Purity and Production in Saccharopolyspora erythraea Fermentation. Applied and Environmental Microbiology.DOI
Siliang Zhang (2008). Using oxidation-reduction potential to optimize lactic acid production by Lactobacillus paracasei. Shengwu jiagong guocheng.
Siliang Zhang (2008). Performance of the Frusto-Conical Bottom Bioreactor in Mammalian Cell Suspension Culture. Huadong Li-Gong Daxue xuebao.
Siliang Zhang (2008). Adaptation of Baby Hamster Kidney(BHK21) Cells to Culture with Low Serum Medium and the Comparison of Cell Primary Metabolism. Chemistry & Bioengineering.
Siliang Zhang (2008). Effect of Methanol Concentration on S-Adenosyl-L-Methionine Production in Recombinant Pichia pastoris. Huadong Li-Gong Daxue xuebao.
Siliang Zhang (2008). A Novel In-situ Microscope and Its Application in Bioreactor. Zhongguo shengwu gongcheng zazhi.
Siliang Zhang (2008). Effect of Glutamine Limitation on Growth, Metabolism and MAb Production of Hybridoma Cells. Journal of Chemical Engineering of Chinese Universities.
Siliang Zhang (2008). CFD Simulation of Mixing Process in Stirred Bioreactor and Its Application in Fermentation. Chemistry & Bioengineering.
Siliang Zhang (2008). Effect of Ammonium on Biosynthesis of Bitespiramycin. Huadong Li-Gong Daxue xuebao.
Zhenlin Li, Yonghong Wang, Ju Chu, Yingping Zhuang, Siliang Zhang (2008). Leucine improves the component of isovalerylspiramycins for the production of bitespiramycin. Bioprocess and Biosystems Engineering.DOI
Haifeng Hang, Xinhao Ye, Meijin Guo, Ju Chu, Yingping Zhuang, Ming Zhang, Siliang Zhang (2008). A simple fermentation strategy for high-level production of recombinant phytase by Pichia pastoris using glucose as the growth substrate. Enzyme and Microbial Technology.DOI
Jianye Xia, Yonghong Wang, Siliang Zhang, Ning Chen, Peng Yin, Yingping Zhuang, Ju Chu (2008). Fluid dynamics investigation of variant impeller combinations by simulation and fermentation experiment. Biochemical Engineering Journal.DOI
Xiang Zou, Haifeng Hang, Ju Chu, Yingping Zhuang, Siliang Zhang (2008). Oxygen uptake rate optimization with nitrogen regulation for erythromycin production and scale-up from 50L to 372m3 scale. Bioresource Technology.DOI
Wen Liu, Siliang Zhang, Yun Chen, Wei Deng, Jiequn Wu (2008). Improvement of Erythromycin a purity and production at the fermentation stage of Saccharopolyspora erytharea by metabolic engineering. Journal of Biotechnology.DOI
Meijin Guo, Haifeng Hang, Taicheng Zhu, Yingping Zhuang, Ju Chu, Siliang Zhang (2007). Effect of glycosylation on biochemical characterization of recombinant phytase expressed in Pichia pastoris. Enzyme and Microbial Technology.DOI
Jin Zhou, Ju Chu, Yonghong Wang, Hui Wang, Yingping Zhuang, Siliang Zhang (2007). Purification and bioactivity of exendin-4, a peptide analogue of GLP-1, expressed in Pichia pastoris. Biotechnology Letters.DOI
Rui Guo, Ming Ding, Siliang Zhang, Gen-Jun Xu, Fu-kun Zhao (2007). Molecular cloning and characterization of two novel cellulase genes from the mollusc Ampullaria crossean. Journal of Comparative Physiology B.DOI
Yong Wang, Yiguang Wang, YiGuang Wang, Yiguang Wang, Siliang Zhang (2007). High frequency transformation of the industrial erythromycin-producing bacterium Saccharopolyspora erythraea. Biotechnology Letters.DOI
Yu-You Hao, Qiqi Shi, Yun He, Yingping Zhuang, Yonghong Wang, Siliang Zhang, Ju Chu, Zhimin Liu (2007). High-expression of recombinant human concensus interferon-α by Pichia pastoris. Frontiers of Chemical Science and Engineering.DOI
Meijin Guo, Yingping Zhuang, Ju Chu, Siliang Zhang, Ai‐Sheng Xiong, Ri‐He Peng, Quan‐Hong Yao (2007). Production and purification of a novel thermostable phytase by Pichia pastoris FPHY34. Process Biochemistry.DOI
Jin Zhou, Ju Chu, Yonghong Wang, Siliang Zhang, Yingping Zhuang, Zhongyi Yuan (2007). Purification and properties of Saccharomyces cerevisiae S-adenosylmethionine synthetase expressed in recombinant Pichia pastoris. World Journal of Microbiology and Biotechnology.DOI
Jianye Xia, Sijing Wang, Siliang Zhang, Jian‐Jiang Zhong (2007). Computational investigation of fluid dynamics in a recently developed centrifugal impeller bioreactor. Biochemical Engineering Journal.DOI
XU Guo-qian, Ju Chu, Yingping Zhuang, Yonghong Wang, Siliang Zhang (2007). Effects of vitamins on the lactic acid biosynthesis of Lactobacillus paracasei NERCB 0401. Biochemical Engineering Journal.DOI
Yong Wang, Yiguang Wang, Yiguang Wang, Yiguang Wang, 储炬, Siliang Zhang, Lixin Zhang, Siliang Zhang (2007). Improved production of erythromycin A by expression of a heterologous gene encoding S-adenosylmethionine synthetase. Applied Microbiology and Biotechnology.DOI
Huaxin Chen, Ju Chu, Siliang Zhang, Yingping Zhuang, Jiangchao Qian, Yonghong Wang, Xiaoqing Hu (2007). Intracellular expression of Vitreoscilla hemoglobin improves S-adenosylmethionine production in a recombinant Pichia pastoris. Applied Microbiology and Biotechnology.DOI
Lei Feng, Meijin Guo, Shuxiang Zhang, Ju Chu, Yingping Zhuang, Siliang Zhang (2007). Optimization of transfection mediated by calcium phosphate for plasmid rAAV‐LacZ (recombinant adeno‐associated virus–β‐galactosidase reporter gene) production in suspension‐cultured HEK‐293 (human embryonic kidney 293) cells. Biotechnology and Applied Biochemistry.DOI
Siliang Zhang (2007). Influences of Methanol Utilization Phenotype and Gene Dosage on Heterologous Protein Expression in Recombinant Pichia pastoris. Zhongguo shengwu gongcheng zazhi.
Siliang Zhang (2007). Influence of Amino Acids on the Production of Adenosine by Bacillus sp. ATCC21616. Huadong Li-Gong Daxue xuebao.
Siliang Zhang (2007). Effects of Isovaleric Acid on the Biosynthesis of Biotechspiramycin. Huadong Li-Gong Daxue xuebao.
Siliang Zhang (2007). Effect of glucose concentration on metabolic flux distribution of hybridoma cells. Journal of Chemical Industry and Engineering.
Siliang Zhang (2007). Phase Transfer Bioconversion of Penicillin G into 6-APA by Immobilized Penicillin Acylase in Recycling Aqueous Two-phase Systems With Light-pH Sensitive Copolymers. Zhongguo shengwu gongcheng zazhi.
Yu-You Hao, Ju Chu, Yonghong Wang, Yingping Zhuang, Siliang Zhang (2006). The inhibition of aggregation of recombinant human consensus interferon-α mutant during Pichia pastoris fermentation. Applied Microbiology and Biotechnology.DOI
Xiaoqing Hu, Ju Chu, Siliang Zhang, Yingping Zhuang, Yonghong Wang, Shan Zhu, Zhigang Zhu, Zhongyi Yuan (2006). A novel feeding strategy during the production phase for enhancing the enzymatic synthesis of S-adenosyl-l-methionine by methylotrophic Pichia pastoris. Enzyme and Microbial Technology.DOI
XU Guo-qian, Ju Chu, Yonghong Wang, Yingping Zhuang, Siliang Zhang, Hua-qiong Peng (2006). Development of a continuous cell-recycle fermentation system for production of lactic acid by Lactobacillus paracasei. Process Biochemistry.DOI
Jiangchao Qian, Xianpeng Cai, Ju Chu, Yingping Zhuang, Siliang Zhang (2006). Nucleotide mutations in purA gene and pur operon promoter discovered in guanosine- and inosine-producing Bacillus subtilis strains. Biotechnology Letters.DOI
Yu-You Hao, Ju Chu, Yonghong Wang, Siliang Zhang, Yingping Zhuang (2006). Expression and Aggregation of Recombinant Human Consensus Interferon-α Mutant by Pichia pastoris. Biotechnology Letters.DOI
Siliang Zhang, Bang‐Ce Ye, Ju Chu, Yingping Zhuang, Meijin Guo (2006). From multi‐scale methodology to systems biology: to integrate strain improvement and fermentation optimization. Journal of Chemical Technology & Biotechnology.DOI
Yingping Zhuang, Wenfeng Ma, Meijin Guo, Man-Sheng Ding, Ju Chu, Siliang Zhang (2006). High cell density and high expression of recombinant human ApoA-IMilano in Escherichia coli by twice temperature-shifted induction. Frontiers in Biology.DOI
Siliang Zhang (2006). Degradation of Reteplase Expressed by Recombinant Pichia pastoris. Huadong Li-Gong Daxue xuebao.
Siliang Zhang (2006). Culture Conditions Affecting High Level Expression of Porcine Insulin Precursor(PIP) by Recombinant Pichia pastoris in High Cell Density Fermentation. Huadong Li-Gong Daxue xuebao.
Siliang Zhang (2006). Artificial Neural Network-based Modeling of Biomass Concentration of Recombinant Yeast Pichia Pastoris at Expression Phase. Huagong zidonghua ji yibiao.
Siliang Zhang (2006). Assessing Viability of Recombinant Pichia pastoris in Fermentation Process with Flow Cytometry. Huadong Li-Gong Daxue xuebao.
Ying Zhuang, Bin Chen, Ju Chu, Siliang Zhang (2005). Medium optimization for meilingmycin production by Streptomyces nanchangensis using response surface methodology. Process Biochemistry.DOI
Shuangxi Chen, Ju Chu, Yingping Zhuang, Siliang Zhang (2005). Enhancement of inosine production by Bacillus subtilis through suppression of carbon overflow by sodium citrate. Biotechnology Letters.DOI
Ju Chu, Siliang Zhang, Yingping Zhuang, Yongbo Song, Xianpeng Cai (2004). Correlation between key enzyme activities in the inosine synthetic pathway and inosine production. Process Biochemistry.DOI
Ju Chu, Siliang Zhang, Yingping Zhuang (2004). Optimization of cultural conditions for enhancing the expression of human interferon-α2a by recombinant yeast. Process Biochemistry.DOI
Jie Chen, Siliang Zhang, Ju Chu, Yingping Zhuang, Jiali Luo, Hua Bai (2004). Ethanol evolution rate: a new parameter to determine the feeding rate for the production of avermectins by Streptomyces avermitilis. Biotechnology Letters.DOI
Yi Xu, Jian‐He Xu, Jiang Pan, Liang Zhao, Siliang Zhang (2003). Biocatalytic resolution of nitro-substituted phenoxypropylene oxides with Trichosporon loubierii epoxide hydrolase and prediction of their enantiopurity variation with reaction time. Journal of Molecular Catalysis B Enzymatic.DOI
Ju Chu, Wenze Niu, Siliang Zhang, Yingping Zhuang, Hui Hu, Yourong Li (2003). Effect of metal ions on the binding of gentamicin to the peptidoglycan of Micromonospora echinospora. Process Biochemistry.DOI
Ju Chu, Siliang Zhang, Yingping Zhuang (2003). Fermentation Process Optimization of Recombinant Saccharomyces cerevisiae for the Production of Human Interferon-α2a. Applied Biochemistry and Biotechnology.DOI
Ju Chu, Siliang Zhang, Yingping Zhuang, Jie Chen, Yourong Li (2002). Factors affecting the biosynthesis and secretion of gentamicin. Process Biochemistry.DOI
Yonghong Wang, Yuanguang Li, Dingji Shi, Guomin Shen, Binggen Ru, Siliang Zhang (2002). Characteristics of mixotrophic growth of Synechocystis sp. in an enclosed photobioreactor. Biotechnology Letters.DOI
Ju Chu, Bailin Li, Siliang Zhang, You‐Rong Li (2000). On-line ultrasound stimulates the secretion and production of gentamicin by Micromonospora echinospora. Process Biochemistry.DOI
Qing‐Shan Li, Siliang Zhang, Jutang Yu (1996). Immobilization of L-glutamate oxidase and peroxidase for glutamate determination in flow injection analysis system. Applied Biochemistry and Biotechnology.DOI
Qingshan Li, Siliang Zhang, Yu Juntang (1995). 1,1′-Dimethylferrocene Mediated L-Glutamate Electrodes Modified With Electropolymerized 1,3-Diaminobenzene Film. Analytical Letters.DOI
Guan Wang, Ali Mohsin, Ju Chu, Yingping Zhuang, Siliang Zhang (2024). Advances and prospects for advanced biomanufacturing. Elsevier eBooks.DOI
Jianye Xia, Guan Wang, Jihan Lin, Yonghong Wang, Ju Chu, Yingping Zhuang, Siliang Zhang (2015). Advances and Practices of Bioprocess Scale-up. Advances in biochemical engineering, biotechnology.DOI
Siliang Zhang, Xuejun Cao, Ju Chu, Jiangchao Qian, Yingping Zhuang (2010). Bioreactors and Bioseparation. Advances in biochemical engineering, biotechnology.DOI
Siliang Zhang, Ju Chu, Yingping Zhuang (2004). A Multi-Scale Study of Industrial Fermentation Processes and Their Optimization. Advances in biochemical engineering, biotechnology.DOI