百晓学者学者目录

冶亚平

副教授、教授、硕士生导师，南方医科大学

精选作品

期刊论文

2026

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Xin Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiu-Bei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hong-Li Jiao

Advancement of science

DOI

2026

FDX1 Depletion Activates CD8 + T Cell Antitumor Immunity by Promoting DMBT1 Secretion in Cuproptosis of Colorectal Cancer

Jieqiong Wu, Zai-Xi Lian, Mingzhou Li, Xin Qin, Xiaoyu Lei, Li-Hua Yang, Lin Bing, Qiuyu Li, Lingyan Zhou, Zhiyan Ma, Xue-Mei Xu, Jinghao Huang, Zilong Chen, Li-jie Chen, Ling-jie Zhang, Zhiyuan Xiao, Xiangyu Jian, Xiao-Qing Zhang, Yanqing Ding, Yaping Ye, Li Liang, Hong-Li Jiao, Shu-yang Wang

Cancer Science

DOI

2024

Nup210 promotes colorectal cancer progression by regulating nuclear plasma transport.

Fang-yi Han, Xingdi Fan, Min-Xuan Hu, Jing Wen, Junrao Wang, Dan Zhang, Shuyang Wang, Yanqing Ding, Yaping Ye, Hong-Li Jiao

Laboratory investigation; a journal of technical methods and pathology

DOI

2024

Correction: Hsa_circ_001680 affects the proliferation and migration of CRC and mediates its chemoresistance by regulating BMI1 through miR-340

Xiangyu Jian, Han He, Jiehong Zhu, Qi Zhang, Zhongxi Zheng, Xiangjing Liang, Liuyan Chen, Meiling Yang, Kai-Yue Peng, Zhaowen Zhang, Teng-Fei Liu, Yaping Ye, Hong-Li Jiao, Shuyang Wang, Wei-Jie Zhou, Yanqing Ding, Tingting Li

Molecular Cancer

DOI

2022

SAFB通过调节Wnt信号通路活性促进结直肠癌增殖

焦红丽，王珺娆，胡敏萱，黄元，丁彦青，冶亚平

《临床与实验病理学杂志》

2022

miR-365a-3p通过BMI1基因影响结直肠癌干细胞特性抑制结直肠癌发生发展的机制研究

何涵，冶亚平，阴常欣，周玲玲，昌媛，李婷婷

《中国医药科学》

2022

A-to-I RNA editing of BLCAP promotes cell proliferation by losing the inhibitory of Rb1 in colorectal cancer.

Fang-yi Han, Minxuan Hu, Lin-Jie Zhang, Xingdi Fan, Junrao Wang, Zhengchi Lou, Shu-yang Wang, Lijie Chen, Yaping Ye, Yan Ding, Hong-Li Jiao

Experimental Cell Research

DOI

2022

FOXS1 Promotes Tumor Progression by Upregulating CXCL8 in Colorectal Cancer

Jun-Feng Qiu, Mingzhou Li, C. Su, Yi-min Liang, Ruizhang Ou, Xiaoning Chen, Chengmei Huang, Yaxin Zhang, Yaping Ye, Wen-Ting Liao, C. Zhang

Frontiers in Oncology

DOI

2022

IGF2BP3 promotes progression of colorectal cancer and mediates cetuximab resistance by stabilizing EGFR mRNA in an m6A-dependent mechanism

Hong-Li Jiao, Lijie Chen, Huiye Liu, Zhiyuan Xiao, Ting Qiu, Dan Zhang, Ling-jie Zhang, Fang-yi Han, Guo-Jun Chen, Xu-Zhi Xu, Jiong-Huan Zhu, Shu-yang Wang, Yan-Qing Ding, Yaping Ye

DOI

2022

COPA A-to-I RNA editing hijacks endoplasmic reticulum stress to promote metastasis in colorectal cancer

Shuyang Wang, Lingjie Zhang, Guo-jun Chen, Qi-Qi Ni, Yuan Huang, Dan Zhang, Fangyi Han, Wenfeng He, Li-ling He, Yanqing Ding, Hong‐Li Jiao, Yaping Ye

Cancer Letters

DOI

2022

Retraction Note: Upregulation of OSBPL3 by HIF1A promotes colorectal cancer progression through activation of RAS signaling pathway

Hong‐Li Jiao, Bin-shu Weng, Shanshan Yan, Zimo Lin, Shuyang Wang, Xiaoping Chen, Guang-hua Liang, Xiaoqing Li, Weiyi Zhao, Jiayi Huang, Dan Zhang, Lingjie Zhang, Fangyi Han, Shengnan Li, Lijie Chen, Jiong-Hua Zhu, Wenfeng He, Yanqing Ding, Yaping Ye

Cell Death and Disease

DOI

2021

Correction to: MicroRNA-224 sustains Wnt/β-catenin signaling and promotes aggressive phenotype of colorectal cancer

Tingting Li, Qiuhua Lai, Shu-yang Wang, Juanjuan Cai, Zhiyuan Xiao, Dan-ling Deng, Liuqing He, Hong-Li Jiao, Yaping Ye, L. Liang, Yan Ding, Wen-Ting Liao

Journal of experimental & clinical cancer research : CR

DOI

2020

VCAM1 Promotes Tumor Cell Invasion and Metastasis by Inducing EMT and Transendothelial Migration in Colorectal Cancer

Dan Zhang, Jiaxin Bi, Qiaoyan Liang, Shu-yang Wang, Ling-jie Zhang, Fang-yi Han, Sheng-Nan Li, B. Qiu, Xingdi Fan, Wei Chen, Hong-Li Jiao, Yaping Ye, Yan-Qing Ding

Frontiers in Oncology

DOI

2020

Hsa_circ_001680 affects the proliferation and migration of CRC and mediates its chemoresistance by regulating BMI1 through miR-340

Xiangyu Jian, Han He, Jiehong Zhu, Qi Zhang, Zhongxin Zheng, Xiangjing Liang, Liuyan Chen, Mengsu Yang, Kai-Yue Peng, Zhaowen Zhang, Teng-Fei Liu, Yaping Ye, Hong-Li Jiao, Shu-yang Wang, Wei-Jie Zhou, Yan-Qing Ding, Tingting Li

Molecular Cancer

DOI

2020

Downregulation of Siah1 promotes colorectal cancer cell proliferation and migration by regulating AKT and YAP ubiquitylation and proteasome degradation

Zhiyuan Xiao, Zhi-Hong Wei, Dan-ling Deng, Z. Zheng, Yali Zhao, Sheng Jiang, Dan Zhang, Ling-jie Zhang, M. Fan, Siqi Chen, Shu-yang Wang, Yan-Qing Ding, Yaping Ye, Hong-Li Jiao

Cancer Cell International

DOI

2020

CREB5 promotes invasiveness and metastasis in colorectal cancer by directly activating MET

Shu-yang Wang, Jun-Feng Qiu, Lei Liu, Cailin Su, L. Qi, Chengmei Huang, Xiaoning Chen, Yaxin Zhang, Yaping Ye, Yan-Qing Ding, L. Liang, Wen-Ting Liao

Journal of experimental & clinical cancer research : CR

DOI

2020

RETRACTED ARTICLE: Upregulation of OSBPL3 by HIF1A promotes colorectal cancer progression through activation of RAS signaling pathway

Hong‐Li Jiao, Bin-shu Weng, Shan-shan Yan, Zimo Lin, Shuyang Wang, Xiao-ping Chen, Guang-hua Liang, Xiaoqing Li, Weiyi Zhao, Jia-Yi Huang, Dan Zhang, Ling-jie Zhang, Fangyi Han, Sheng-nan Li, Lijie Chen, Jiong-Hua Zhu, Wenfeng He, Yanqing Ding, Yaping Ye

Cell Death and Disease

DOI

2019

UBN2 promotes tumor progression via the Ras/MAPK pathway and predicts poor prognosis in colorectal cancer

Yali Zhao, Shenrong Zhong, Shihong Zhang, Jiaxin Bi, Zhiyuan Xiao, Shuyang Wang, Hong‐Li Jiao, Dan Zhang, Junfeng Qiu, Ling-Jie Zhang, Chengmei Huang, Xiaoling Chen, Yanqing Ding, Yaping Ye, Liang Li, Wenting Liao

Cancer Cell International

DOI

2018

INHBA基因表达上调与左、右半结肠癌临床病理特征及预后的相关性

周薇，毕嘉欣，冶亚平，丁彦青

《临床与实验病理学杂志》

2018

FOXF1 promotes angiogenesis and accelerates bevacizumab resistance in colorectal cancer by transcriptionally activating VEGFA.

Shu-yang Wang, Zhiyuan Xiao, Zexuan Hong, Hong-Li Jiao, Shaowei Zhu, Yali Zhao, Jiaxin Bi, Jun-Feng Qiu, Dan Zhang, Junyu Yan, Ling-jie Zhang, Chengmei Huang, Tingting Li, L. Liang, Wen-Ting Liao, Yaping Ye, Yan-Qing Ding

Cancer Letters

DOI

2018

STX2 promotes colorectal cancer metastasis through a positive feedback loop that activates the NF-κB pathway

Yong-Xia Wang, Hong-Hai Xu, Hong-Li Jiao, Shu-yang Wang, Zhiyuan Xiao, Yali Zhao, Jiaxin Bi, Wen-Ting Wei, Shanshan Liu, Jun-Feng Qiu, Tingting Li, L. Liang, Yaping Ye, Wen-Ting Liao, Yan Ding

Cell Death and Disease

DOI

2018

MiR-452 promotes an aggressive colorectal cancer phenotype by regulating a Wnt/β-catenin positive feedback loop

Tingting Li, Xiangyu Jian, Han He, Qiuhua Lai, Xian-Zheng Li, Dan-ling Deng, Teng-Fei Liu, Jiehong Zhu, Hong-Li Jiao, Yaping Ye, Shu-yang Wang, Min-Hui Yang, Lin Zheng, Wei-Jie Zhou, Yan-Qing Ding

Journal of experimental & clinical cancer research : CR

DOI

2018

Hypermethylation of DMTN promotes the metastasis of colorectal cancer cells by regulating the actin cytoskeleton through Rac1 signaling activation

Yaping Ye, Hong‐Li Jiao, Shuyang Wang, Zhiyuan Xiao, Dan Zhang, Junfeng Qiu, Lingjie Zhang, Yali Zhao, Tingting Li, Li-Liang, Wenting Liao, Yanqing Ding

Journal of Experimental & Clinical Cancer Research

DOI

2018

FOXF1 Induces Epithelial-Mesenchymal Transition in Colorectal Cancer Metastasis by Transcriptionally Activating SNAI1

Shuyang Wang, Shanshan Yan, Shaowei Zhu, Yali Zhao, Junyu Yan, Zhiyuan Xiao, Jiaxin Bi, Junfeng Qiu, Dan Zhang, Zexuan Hong, Lingjie Zhang, Chengmei Huang, Tingting Li, Liang Li, Wenting Liao, Hong‐Li Jiao, Yanqing Ding, Yaping Ye

Neoplasia

DOI

2017

miR-422a inhibits cell proliferation in colorectal cancer by targeting AKT1 and MAPK1

Wen-Ting Wei, Xin-Xin Nian, Shuyang Wang, Hong‐Li Jiao, Yong‐Xia Wang, Zhiyuan Xiao, Runwei Yang, Yanqing Ding, Yaping Ye, Wenting Liao

Cancer Cell International

DOI

2017

Downregulation of SAFB Sustains the NF- κ B Pathway by Targeting TAK1 during the Progression of Colorectal Cancer

Hong‐Li Jiao, Yaping Ye, Runwei Yang, Huiying Sun, Shuyang Wang, Yong‐Xia Wang, Zhiyuan Xiao, Liuqing He, Juanjuan Cai, Wenting Wei, Yanru Chen, Chun-Cai Gu, Yue-Long Cai, Yun-Teng Hu, Qiuhua Lai, Junfeng Qiu, Liang Li, Guangwen Cao, Wenting Liao, Yanqing Ding

Clinical Cancer Research

DOI

2016

MicroRNA-224 sustains Wnt/β-catenin signaling and promotes aggressive phenotype of colorectal cancer

Tingting Li, Qiuhua Lai, Shu-yang Wang, Juanjuan Cai, Zhiyuan Xiao, Dan-ling Deng, Liuqing He, Hong-Li Jiao, Yaping Ye, L. Liang, Yan-Qing Ding, Wen-Ting Liao

Journal of experimental & clinical cancer research : CR

DOI

2016

MiR-384 inhibits human colorectal cancer metastasis by targeting KRAS and CDC42

Yong‐Xia Wang, Yanru Chen, Shanshan Liu, Yaping Ye, Hong‐Li Jiao, Shuyang Wang, Zhiyuan Xiao, Wenting Wei, Junfeng Qiu, Liang Li, Wenting Liao, Yanqing Ding

Oncotarget

DOI

2016

miR-450b-5p induced by oncogenic KRAS is required for colorectal cancer progression

Yaping Ye, Ping Wu, Chun-Cai Gu, Danling Deng, Hong‐Li Jiao, Tingting Li, Shuyang Wang, Yong‐Xia Wang, Zhiyuan Xiao, Wenting Wei, Yanru Chen, Junfeng Qiu, Runwei Yang, Jie Lin, Li Liang, Wenting Liao, Yanqing Ding

Oncotarget

DOI

2015

The tumor-suppressor gene LZTS1 suppresses colorectal cancer proliferation through inhibition of the AKT–mTOR signaling pathway

Wei Zhou, Mei-Rong He, Hong‐Li Jiao, Liuqing He, Danling Deng, Juanjuan Cai, Zhiyuan Xiao, Yaping Ye, Yanqing Ding, Wenting Liao, Side Liu

Cancer Letters

DOI

2015

TLE4 promotes colorectal cancer progression through activation of JNK/c-Jun signaling pathway

Shuyang Wang, Ke Gao, Danling Deng, Juanjuan Cai, Zhiyuan Xiao, Liuqing He, Hong‐Li Jiao, Yaping Ye, Runwei Yang, Tingting Li, Liang Li, Wenting Liao, Yanqing Ding

Oncotarget

DOI

2014

miR-30b对结直肠癌细胞转移潜能的影响

吴萍，冶亚平，丁彦青，廖雯婷

《中国肿瘤临床》

2014

EPB49在结直肠癌发生发展和转移过程中的作用和分子机制研究

冶亚平

《南方医科大学》

2014

The function of miR-30b in colorectal cancer metastasis

Ping Wu, Yaping Ye, Yan-Qing Ding, Wen-Ting Liao

2014

FOXC2 promotes colorectal cancer proliferation through inhibition of FOXO3a and activation of MAPK and AKT signaling pathways

Yanmei Cui, Dan Jiang, Shihong Zhang, Ping Wu, Yaping Ye, Cui-Min Chen, Na Tang, Liang Li, Tingting Li, Lu Qi, Shuyang Wang, Hong‐Li Jiao, Jie Lin, Yanqing Ding, Wenting Liao

Cancer Letters

DOI

2014

Metastatic cancer stem cells: from the concept to therapeutics.

Wenting Liao, Yaping Ye, Yong‐Jian Deng, Xiu‐Wu Bian, Yan-qing Ding

PubMed

2013

microRNA-224 Promotes Cell Proliferation and Tumor Growth in Human Colorectal Cancer by Repressing PHLPP1 and PHLPP2

Wenting Liao, Tingting Li, Zheng-Gen Wang, Shuyang Wang, Mei-Rong He, Yaping Ye, Lu Qi, Yanmei Cui, Ping Wu, Hong‐Li Jiao, Chi Zhang, Yijun Xie, Jun‐Xian Wang, Yanqing Ding

Clinical Cancer Research

DOI

2012

大肠癌转移相关分子标签的筛选

齐鲁，袁理，吴萍，冶亚平，丁彦青

《现代生物医学进展》

2006

cyclinD1甲基化程度降低与大肠癌的关系

崔静，张景航，张洁，冶亚平，千新来

《新乡医学院学报》

预印本

2024

Integrated Spatial Multi-Omics Analysis Reveals Novel Immunoinflammatory CD8+ T Cells Associated with Tertiary Lymphoid Structure and Immunotherapy Response in Colorectal Cancer

Yuan Huang, Ranyang Cheng, Nan Hu, Kaiyu Lou, Xuemei Xu, Bin Huang, Qinyu Yang, Lijie Chen, Tingting Li, Zhiyuan Xiao, Shuyang Wang, Yaping Ye, Hong‐Li Jiao

Research Square

DOI

研究方向

结直肠癌发生与演进分子机制结直肠癌与肿瘤免疫逃逸

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