曹爽｜武汉工程大学｜学者主页

2026

香豆素衍生物合成的综合实验设计

王彦恩，曹爽，刘海燕，武伟红，崔朋雷，唐然肖

《佳木斯大学学报(自然科学版)》

DOI

2025

α2,6连接的氟代唾液酸寡糖的化学酶法合成

曹爽，仲侃，李春霞

《中国海洋药物》

DOI

2025

Diverse pharmacological activities of β-carbolines: Substitution patterns, SARs and mechanisms of action

Muneeb Ur Rehman, Yujie Zuo, Ni Tu, Ju Guo, Ziwei Liu, Shuang Cao, Sihui Long

European Journal of Medicinal Chemistry

DOI

2025

SMARCA2 protein: Structure, function and perspectives of drug design

Zhaolin Guo, Peng Wang, Yuxuan Han, Sisi Jiang, Xinyu Yang, Shuang Cao

European Journal of Medicinal Chemistry

DOI

2025

TDO Target Inhibitor Research Progress Review

Yuxuan Han, Peng Wang, Zhaolin Guo, Anran Xiang, Shuang Cao, Yong-Shou Chen

Journal of Biosciences and Medicines

DOI

2024

Corrigendum to “Antibacterial and antifungal pyrazoles based on different construction strategies” [Euro. J. Med. Chem. 282 (2025) 117081]

Muneeb Ur Rehman, Fang He, Xi Shu, Ju Guo, Ziwei Liu, Shuang Cao, Sihui Long

European Journal of Medicinal Chemistry

DOI

2024

Antibacterial and antifungal pyrazoles based on different construction strategies

Muneeb Ur Rehman, Fang He, Xi Shu, Ju Guo, Ziwei Liu, Shuang Cao, Sihui Long

European Journal of Medicinal Chemistry

DOI

2024

Recent advances in peptoids as promising antimicrobial agents to target diverse microbial species

Yi Gao, Jianzhou Cui, Shuang Cao, Ju Guo, Ziwei Liu, Sihui Long

European Journal of Medicinal Chemistry

DOI

2024

Anticancer α-, γ-, and δ-carboline derivatives: structures, mechanisms of action, and SARs

Jingliang Cui, Wanru Gao, Ziwei Liu, Shuang Cao, Sihui Long

European Journal of Medicinal Chemistry Reports

DOI

2023

RNA-binding MSI proteins and their related cancers: A medicinal chemistry perspective

Chenxin Liu, Haiyan Chen, Shuang Cao, Ju Guo, Ziwei Liu, Sihui Long

Bioorganic Chemistry

DOI

2023

Recent advances in 1,2,3- and 1,2,4-triazole hybrids as antimicrobials and their SAR: A critical review

Guimiao Tian, Qiuyi Song, Ziwei Liu, Ju Guo, Shuang Cao, Sihui Long

European Journal of Medicinal Chemistry

DOI

2023

Virtual screening and molecular growth guide the design of inhibitors for the influenza virus drug-resistant mutant M2-V27A/S31N

Changyong Deng, Xiaobo Wang, Tangle Wang, Wei Yong Liu, Xiaolan Yuan, Yan Huang, Shuang Cao

Journal of Biomolecular Structure and Dynamics

DOI

2023

Recent advances in anticancer peptoids

Jidan Zhu, Siyu Chen, Ziwei Liu, Ju Guo, Shuang Cao, Sihui Long

Bioorganic Chemistry

DOI

2023

A novel compound to overcome influenza drug resistance in endonuclease inhibitors

Yixin Ren, Li Wan, Shuang Cao

Molecular Diversity

DOI

2022

Recent Advances in Anti-Coxsackievirus A16 Viral Drug Research

Xiaolan Yuan, Ziwei Liu, Li Wan, Wei Yong Liu, Yan Huang, Shuang Cao

Future Medicinal Chemistry

DOI

2022

Targeted Inhibition of the Endonuclease Activity of Influenza Polymerase Acidic Proteins

Yixin Ren, Yong-Shou Chen, Shuang Cao

Future Medicinal Chemistry

DOI

2022

Glucokinase as an emerging anti-diabetes target and recent progress in the development of its agonists

Yixin Ren, Li Li, Li Wan, Yan Huang, Shuang Cao

Journal of Enzyme Inhibition and Medicinal Chemistry

DOI

2021

Molecular Docking and Virtual Screening of an Influenza Virus Inhibitor That Disrupts Protein–Protein Interactions

Yixin Ren, Sihui Long, Shuang Cao

Viruses

DOI

2021

GLUT1 Biological Function and Inhibition: Research Advances

Shuang Cao, Yong-Shou Chen, Yixin Ren, Yingqi Feng, Sihui Long

Future Medicinal Chemistry

DOI

2021

Novel small molecular inhibitor of Pit-Oct-Unc transcription factor 1 suppresses hepatocellular carcinoma cell proliferation

Yue Wang, Shuo Liu, Qin Chen, Yixin Ren, Zhongxiang Li, Shuang Cao

Life Sciences

DOI

2021

Rhamnetin decelerates the elimination and enhances the antitumor effect of the molecular-targeting agent sorafenib in hepatocellular carcinoma cells via the miR-148a/PXR axis

Boan Li, Fan Feng, Hui Min Jia, Qiyu Jiang, Shuang Cao, Ling Wei, Yingshi Zhang, Jincai Lu

Food & Function

DOI

2020

二苯基嘧啶类化合物抗癌活性的研究进展

古双喜，王超，曹爽，王海峰

《武汉工程大学学报》

DOI

2020

Identification of active chemical constituents of Asplenium ruprechtii Sa. Kurata based on in vitro neuroprotective activity evaluation

Zhibo Jiang, Xing Lu, Jing-Zhi Chen, Xiaoli Ma, Yihu Ke, Xin Guo, Hai Liu, Chonglong Li, Fang Wang, Xiuli Wu, Dai-Zhou Zhang, Shuang Cao

Arabian Journal of Chemistry

DOI

2020

Recent discoveries in HIV-1 reverse transcriptase inhibitors

Shuang‐Xi Gu, Yuan‐Yuan Zhu, Chao Wang, Haifeng Wang, Genyan Liu, Shuang Cao, Lu Huang

Current Opinion in Pharmacology

DOI

2020

Novel mTOR Inhibitor Enhances the Sensitivity of Hepatocellular Carcinoma Cells to Molecular Targeting Agents

Yingqi Feng, Boan Li, Fan Feng, Yong-Shou Chen, Yixin Ren, Heng Zhang, Shuang Cao

OncoTargets and Therapy

DOI

2020

Virtual Screening and Optimization of Novel mTOR Inhibitors for Radiosensitization of Hepatocellular Carcinoma

Yingqi Feng, Shuang‐Xi Gu, Yong-Shou Chen, Xudong Gao, Yixin Ren, Jianchao Chen, Yinying Lu, Heng Zhang, Shuang Cao

Drug Design Development and Therapy

DOI

2020

Steric Effect Determines the Formation of Lactam–Lactam Dimers or Amide C═O···NH (Lactam) Chain Motifs in N-Phenyl-2-hydroxynicotinanilides

Huaxin Liu, Xing Yang, Shuang Cao, Faquan Yu, Sihui Long, Jun Chen, Mingtao Zhang, Sean Parkin, Tonglei Li, Zhaoyong Yang

Crystal Growth & Design

DOI

2020

Anticancer activity evaluation of indazolyl-substituted piperidin-4-yl-aminopyrimidines

Chao Wang, Xiao-Wen Liu, Ting Xiao, Zhi‐Qiang Xu, Shuang Cao, Haifeng Wang, Qiongjiao Yan, Shuang‐Xi Gu, Yuan‐Yuan Zhu

Medicinal Chemistry Research

DOI

2020

Synthesis and Crystal Structure Studies of Mitomycin C Dihydrate

Yingqi Feng, Yong-Shou Chen, Yixin Ren, Heng‐Qiang Zhang, Shuang Cao

Crystal Structure Theory and Applications

DOI

2019

普通针毛蕨中原芹菜素与其糖苷对PDK-1/AKT途径的拮抗效应

韩盼，金灿，曹爽，张慧宏，赖永继，刘子维

《中国医院药学杂志》

DOI

2019

Self-Assembled Naphthalimide Conjugated Porphyrin Nanomaterials with D–A Structure for PDT/PTT Synergistic Therapy

Mengqian Yang, Shuang Cao, Xinzhi Sun, Huifang Su, Haolan Li, Genyan Liu, Xiaogang Luo, Fengshou Wu

Bioconjugate Chemistry

DOI

2019

An investigation of the polymorphism of a potent nonsteroidal anti-inflammatory drug flunixin

Hao Liu, Xing Yang, Shanyu Wu, Mingtao Zhang, Sean Parkin, Shuang Cao, Tonglei Li, Faquan Yu, Sihui Long

CrystEngComm

DOI

2019

The antagonism between apigenin and protoapigenone to the PDK-1 target in Macrothelypteris torresiana

Ziwei Liu, Ziwei Liu, Shuang Cao, Can Jin, Yu Ting He, Xiaoshun Zhou, Heng Zhang, Zhimei Liu, Zhimei Liu

Fitoterapia

DOI

2018

mTOR抑制剂在女性恶性肿瘤治疗中的应用进展

冯瑛琪，张珩，陈永收，任一鑫，曹爽

《国际药学研究杂志》

2018

Novel ADAM-17 inhibitor ZLDI-8 enhances the in vitro and in vivo chemotherapeutic effects of Sorafenib on hepatocellular carcinoma cells

Yingshi Zhang, Dandan Li, Qiyu Jiang, Shuang Cao, Huiwei Sun, Yantao Chai, Xiaojuan Li, Tianshu Ren, Ruichuang Yang, Fan Feng, Boan Li, Qingchun Zhao

Cell Death and Disease

DOI

2018

Pregnane X receptor mediates sorafenib resistance in advanced hepatocellular carcinoma

Fan Feng, Qiyu Jiang, Shuang Cao, Yu Wen Cao, Ruisheng Li, Lijun Shen, Hua Zhu, Tao Wang, Lijun Sun, Erguang Liang, Huiwei Sun, Yantao Chai, Xiaojuan Li, Genyan Liu, Ruichang Yang, Zhi Yang, Yongping Yang, Shaojie Xin, Boan Li

Biochimica et Biophysica Acta (BBA) - General Subjects

DOI

2017

二吗啉苯并噻唑苯基脲类选择性PI3Kβ抑制剂的合成

刘夏玲，曹爽，陈思奥，张珩，钟武

《国际药学研究杂志》

2016

抗乙型肝炎病毒药物的研究进展

王宏亮，刘夏玲，曹爽

《国际药学研究杂志》

2016

Design, Synthesis and Biological Evaluation of Novel Benzothiazole Derivatives as Selective PI3Kβ Inhibitors

Shuang Cao, Ruiyuan Cao, Xialing Liu, Xiang Luo, Wu Zhong

Molecules

DOI

2014

哺乳动物西罗莫司靶蛋白的生物功能及其抑制剂研究进展

曹爽，钟武

《国际药学研究杂志》

2013

乙丙昔罗的合成工艺研究

许媛，张珩，杨艺虹，曹爽，钟武

《军事医学》

精选作品

期刊论文

香豆素衍生物合成的综合实验设计

α2,6连接的氟代唾液酸寡糖的化学酶法合成

Diverse pharmacological activities of β-carbolines: Substitution patterns, SARs and mechanisms of action

SMARCA2 protein: Structure, function and perspectives of drug design

TDO Target Inhibitor Research Progress Review

Corrigendum to “Antibacterial and antifungal pyrazoles based on different construction strategies” [Euro. J. Med. Chem. 282 (2025) 117081]

Antibacterial and antifungal pyrazoles based on different construction strategies

Recent advances in peptoids as promising antimicrobial agents to target diverse microbial species

Anticancer α-, γ-, and δ-carboline derivatives: structures, mechanisms of action, and SARs

RNA-binding MSI proteins and their related cancers: A medicinal chemistry perspective

Recent advances in 1,2,3- and 1,2,4-triazole hybrids as antimicrobials and their SAR: A critical review

Virtual screening and molecular growth guide the design of inhibitors for the influenza virus drug-resistant mutant M2-V27A/S31N

Recent advances in anticancer peptoids

A novel compound to overcome influenza drug resistance in endonuclease inhibitors

Recent Advances in Anti-Coxsackievirus A16 Viral Drug Research

Targeted Inhibition of the Endonuclease Activity of Influenza Polymerase Acidic Proteins

Glucokinase as an emerging anti-diabetes target and recent progress in the development of its agonists

Molecular Docking and Virtual Screening of an Influenza Virus Inhibitor That Disrupts Protein–Protein Interactions

GLUT1 Biological Function and Inhibition: Research Advances

Novel small molecular inhibitor of Pit-Oct-Unc transcription factor 1 suppresses hepatocellular carcinoma cell proliferation

Rhamnetin decelerates the elimination and enhances the antitumor effect of the molecular-targeting agent sorafenib in hepatocellular carcinoma cells via the miR-148a/PXR axis

二苯基嘧啶类化合物抗癌活性的研究进展

Identification of active chemical constituents of Asplenium ruprechtii Sa. Kurata based on in vitro neuroprotective activity evaluation

Recent discoveries in HIV-1 reverse transcriptase inhibitors

Novel mTOR Inhibitor Enhances the Sensitivity of Hepatocellular Carcinoma Cells to Molecular Targeting Agents

Virtual Screening and Optimization of Novel mTOR Inhibitors for Radiosensitization of Hepatocellular Carcinoma

Steric Effect Determines the Formation of Lactam–Lactam Dimers or Amide C═O···NH (Lactam) Chain Motifs in N-Phenyl-2-hydroxynicotinanilides

Anticancer activity evaluation of indazolyl-substituted piperidin-4-yl-aminopyrimidines

Synthesis and Crystal Structure Studies of Mitomycin C Dihydrate

普通针毛蕨中原芹菜素与其糖苷对PDK-1/AKT途径的拮抗效应

Self-Assembled Naphthalimide Conjugated Porphyrin Nanomaterials with D–A Structure for PDT/PTT Synergistic Therapy

An investigation of the polymorphism of a potent nonsteroidal anti-inflammatory drug flunixin

The antagonism between apigenin and protoapigenone to the PDK-1 target in Macrothelypteris torresiana

mTOR抑制剂在女性恶性肿瘤治疗中的应用进展

Novel ADAM-17 inhibitor ZLDI-8 enhances the in vitro and in vivo chemotherapeutic effects of Sorafenib on hepatocellular carcinoma cells

Pregnane X receptor mediates sorafenib resistance in advanced hepatocellular carcinoma

二吗啉苯并噻唑苯基脲类选择性PI3Kβ抑制剂的合成

抗乙型肝炎病毒药物的研究进展

Design, Synthesis and Biological Evaluation of Novel Benzothiazole Derivatives as Selective PI3Kβ Inhibitors

哺乳动物西罗莫司靶蛋白的生物功能及其抑制剂研究进展

乙丙昔罗的合成工艺研究