舒乐新｜天津中医药大学｜学者主页

2026

Rapid Classification and Identification of Chemical Constituents of Chelidonium majus L. Based on UHPLC‐Q‐Exactive Orbitrap MS

Lu-Yao Hu, Shu-Feng Tian, Jia-Yi Lin, Sitong Liu, Shulin Zhao, Lili Song, Lexin Shu, Yu-Bo Li

Separation Science Plus

DOI

2026

Rapid Identification of Chemical Constituents of Zanthoxylum nitidum (Roxb.) DC. by Ultra‐High‐Performance Liquid Chromatography Quadrupole‐Exactive Orbitrap Mass Spectrometry

Lu-Yao Hu, Zihan Wan, Lijuan Zhang, Sitong Liu, Bin Yang, Lexin Shu, Yu-Bo Li

Rapid Communications in Mass Spectrometry

DOI

2026

Systematic Characterization of the In Vitro and In Vivo Chemical Constituents of Shenmai Formula by UHPLC-Orbitrap MS.

Xiangying Wang, Jin-Lian Shen, Jun Qian, Shumin Zhang, Hui-Xin Qiu, Sitong Liu, Mengjie Hong, Xiao-Di Kou, Lexin Shu, Yu-Bo Li

Biomedical chromotography

DOI

2026

Single-nucleus RNA Sequencing and multi-omics reveal Uncaria-derived indole alkaloids induce hepatocyte injury by mediating CAR/PPARα axis.

Bin Yang, Xueqian Sun, Xinyue Zhang, Shuo Wang, Ye Wang, Yu-Ming Wang, Shen-Shen Yang, Lexin Shu, Yu-Bo Li

Phytomedicine

DOI

2026

Schisandrin B Attenuates Doxorubicin-Induced Acute Cardiac Injury through Regulation of Metabolites and Gut Microbiota.

Hui-Xin Qiu, Xiangying Wang, Jun Qian, Shumin Zhang, Sitong Liu, Mengjie Hong, Lexin Shu, Qi-Duo Zhao, Yu-Bo Li

European Journal of Pharmacology

DOI

2025

Systematic Characterization of the Chemical Constituents of in Vitro and in Vivo of Astragali Radix-Salvia miltiorrhiza Herb Pair by Ultra-High-Performance-Liquid Chromatography-Orbitrap Mass Spectrometry.

Lexin Shu, Shumin Zhang, Jun Qian, Sitong Liu, Hui-Xin Qiu, Qi-Duo Zhao, Yanru Deng, Yu-Bo Li

Rapid Communications in Mass Spectrometry

DOI

2024

蒽环类药物心脏毒性的中西药防治策略

钱俊，张淑敏，仇慧鑫，刘思彤，邓雁如，舒乐新

《世界科学技术-中医药现代化》

2024

Chemical composition analysis of Qingyan dropping pills using ultra‐high‐performance liquid chromatography‐quadrupole time‐of‐flight mass spectrometry

Lexin Shu, Hui-Xin Qiu, Yu-Fan He, Shumin Zhang, Jun Qian, Sitong Liu, Xiao-Di Kou, Qi-Duo Zhao, Yu-Bo Li

Rapid Communications in Mass Spectrometry

DOI

2024

Unique metabolomics characteristics for distinguishing cirrhosis related to different liver diseases: A systematic review and meta-analysis.

Liu Yang, Fang Wang, Sijia Liu, Zicheng Xian, Shen-Shen Yang, Yan-Yan Xu, Lexin Shu, Xing-Xu Yan, Jun-Jie He, Xia Li, Cheng Peng, Cheng-Hao Bi, Yu Yuan, Siyu Chen, Li-Wen Han, Rongrong Yang, Yu-Bo Li

Diabetes & metabolic syndrome

DOI

2024

Rapid identification and determination of chemical components of huai yam based on UPLC-Q-Exactive-MS and fragmentation patterns

Hui-ru Liu, Xia Li, Haowei Xu, Xiaowen Wang, Zhimin Gong, Yan-Yan Xu, Lexin Shu, Yu-Bo Li

Natural Product Research

DOI

2024

Rapid Identification of Chemical Constituents in New Compound Aloe Capsule Based on UPLC-Q-Orbitrap-MS.

Siyue Chen, Yajie Dou, Shumin Zhang, Hui-Xin Qiu, Hui-ru Liu, Yan-Yan Xu, Lexin Shu, Yu-Bo Li

Rapid Communications in Mass Spectrometry

DOI

2024

Rapid identification of various chemical components in Cinnamomi ramulus by UPLC-Q-Orbitrap-MS.

Lexin Shu, Sitong Liu, Fangfang Zhang, Hui-Xin Qiu, Shumin Zhang, Jun Qian, Yan-Yan Xu, Yanru Deng, Yu-Ming Wang, Yu-Bo Li

Journal of Mass Spectrometry

DOI

2024

Rapid classification and identification of chemical components in three different Zanthoxylum species by ultra-high-performance-liquid chromatography quadrupole-orbitrap-mass spectrometry.

Lexin Shu, Shumin Zhang, Hui-Xin Qiu, Yaqi Yao, Sitong Liu, Jun Qian, Siyue Chen, Qi-Duo Zhao, Yu-Bo Li

Journal of Separation Science

DOI

2023

UPLC-Q-TOF/MS结合网络药理学和分子对接技术探讨山豆根抗肝癌的药效物质及作用机制

王晓雯，张月，胡璐瑶，舒乐新，刘艳普，魏金霞，程文播，蔡挺

《天津中医药》

2023

通脉养心丸减轻阿霉素致小鼠急性心脏毒性的作用研究

吕清波，王彩君，舒乐新，王玉晶，徐津鹏，王怡

《天津中医药》

2023

口服含柴胡制剂治疗部分临床常见病系统评价

咸梓诚，赵艺骏，舒乐新，李遇伯

《中草药》

2023

暴露评估在中药危害物质限量标准中的方法、应用及展望

马宁，陈思越，王玉明，舒乐新，许妍妍，李遇伯

《分析测试学报》

2023

仪器分析实验“三点一线”式教学模式探索

肖玉涵，王佳艺，张悦，韩蕊，李晶芳，殷宏庆，曹颖，舒乐新，宋丽丽，李遇伯

《特产研究》

2023

Analysis of chemical components of Jianwei Xiaoshi Tablets based on UPLC-Q-Orbitrap-MS technology

Jie Ma, Shenshen Yang, Hui-ru Liu, Lexin Shu, Yaqi Yao, Siyue Chen, Yan-Yan Xu, Yu-Bo Li

Natural Product Research

DOI

2023

Rapid identification of chemical compositions of three species of Schisandra chinensis by ultra-high-performance liquid chromatography quadrupole-orbitrap-mass spectrometry.

Lexin Shu, Huixin Qiu, Shu-Min Zhang, Jing-Qin Xue, Sitong Liu, Jun Qian, Siyu Chen, Yan-Yan Xu, Yubo Li

Journal of Separation Science

DOI

2023

Systematic characterization of the chemical constituents in vitro and in vivo of Qianghuo by UPLC-Q-TOF-MS/MS.

Mengru Wu, Luhuan Tang, Yan-Yan Chen, Lexin Shu, Yan-Yan Xu, Yaqi Yao, Yu-Bo Li

Fitoterapia

DOI

2023

A practical method for rapid discrimination of constituents in Psoraleae Fructus by UPLC-Q-Orbitrap MS.

Yan-yan Chen, Luhuan Tang, Mengru Wu, Lexin Shu, Yan-Yan Xu, Yaqi Yao, Yubo Li

Journal of Mass Spectrometry

DOI

2023

Rapid identification of chemical constituents in Hugan tablets by ultra-performance liquid chromatography-quadrupole-exactive orbitrap mass spectrometry.

Xiaowen Wang, Hui-ru Liu, Lexin Shu, Yaqi Yao, Yan-Yan Xu, Jinxia Wei, Yubo Li

Journal of Separation Science

DOI

2023

Integrating Metabolomics and Network Pharmacology to Explore the Mechanism of Tongmai Yangxin Pills in Ameliorating Doxorubicin-Induced Cardiotoxicity

Lexin Shu, Yu-Ming Wang, Wei Huang, Si-Miao Fan, Junhua Pan, Q. Lv, Lin Wang, Yu-Jing Wang, Jinpeng Xu, Hai-Feng Yan, Yu-Chao Bai, Yi Wang, Yubo Li

ACS Omega

DOI

2023

Pharmacological effects and mechanisms of YiYiFuZi powder in chronic heart disease revealed by metabolomics and network pharmacology

Yu-Ming Wang, Xia Li, Min Qi, Xiaokai Li, Fangfang Zhang, Yu-Yu Wang, Jun-Ke Wu, Lexin Shu, Si-Miao Fan, Yunfei Li, Yubo Li

Frontiers in Molecular Biosciences

DOI

2023

Rapid classification and identification of chemical constituents in Leonurus japonicus Houtt based on UPLC-Q-Orbitrap-MS combined with data post-processing techniques.

Yajie Dou, Lexin Shu, Xu Jia, Yaqi Yao, Siyue Chen, Yan-Yan Xu, Yubo Li

Journal of Mass Spectrometry

DOI

2022

中药汤剂治疗蒽环类药物所致心脏毒性的网状Meta分析

李双凤，李春，于瑞丽，咸梓诚，杨丰文，舒乐新，蔡挺

《世界科学技术-中医药现代化》

2022

中药分析实验藿香正气水中乙醇含量测定探讨

舒乐新，刘雪，黄皓宇，魏金霞，许妍妍，李遇伯

《广州化工》

2022

阿霉素急性心脏毒性大鼠造模方法研究

吕清波，潘均华，李帅，王怡，舒乐新

《药物评价研究》

2022

Rapid screening of hepatotoxic components in Uncariae Ramulus Cum Uncis based on "component-target-pathway" network.

Xinyue Zhang, Shuo Wang, Lexin Shu, Shan Zhao, Xing-Xu Yan, Guoxiang Jia, Yue Zhang, Wenqing Zhang, Wenxiu Qian, Bin Yang, Yubo Li

Journal of Pharmaceutical and Biomedical Analysis

DOI

2022

Enantioseparation and determination of oxypeucedanin and its application to a stereoselective analysis in Angelica Dahuricae Radix and pharmacokinetic study of rats.

Luhuan Tang, Yu-Ming Wang, Jia-Xuan Yang, Lexin Shu, Haoran Ding, Yaqi Yao, Yubo Li

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

DOI

2021

通脉养心丸对阿霉素慢性心脏毒性大鼠的保护作用研究

吕清波，潘均华，王玉晶，徐津鹏，王怡，舒乐新

《天津中医药》

2021

A New Strategy for the Rapid Identification and Validation of the Direct Targets of Aconitine-Induced Cardiotoxicity

Jinxia Wei, Si-Miao Fan, Hongxin Yu, Lexin Shu, Yubo Li

Drug Design, Development and Therapy

DOI

2021

DDDT_A_335461 4649..4664

Jinxia Wei, Si-Miao Fan, Hongxin Yu, Lexin Shu, Yubo Li

2020

互联网背景下药物分析混合式教学模式探究

魏金霞，王玉明，许妍妍，舒乐新，冯心池，李遇伯

《广州化工》

2020

Exploration the Mechanism of Doxorubicin-Induced Heart Failure in Rats by Integration of Proteomics and Metabolomics Data

Yu Yuan, Si-Miao Fan, Lexin Shu, Wei Huang, Lijuan Xie, Cheng-Hao Bi, Hongxin Yu, Yu-Ming Wang, Yubo Li

Frontiers in Pharmacology

DOI

2020

Integrated Proteomics and Metabolomics Reveal the Mechanism of Nephrotoxicity Induced by Triptolide.

Lijuan Xie, Yi-Wei Zhao, Jingyi Duan, Si-Miao Fan, Lexin Shu, Hui Liu, Yu-Ming Wang, Yan-Yan Xu, Yubo Li

Chemical Research in Toxicology

DOI

2019

中药化学课程中的一般方法教学设计探讨——以第二章“提取分离”为例

赵启铎，舒乐新，何永志

《黑龙江教育(理论与实践)》

2019

体内药物分析血清中对乙酰氨基酚分析方法的探讨

舒乐新，赵启铎，程子枫，宋丽丽，冯心池

《实验室科学》

2018

临床药学专业体内药物分析课程的教学调查与思考

冯心池，舒乐新，王玉明，邱峰

《药学教育》

2016

关于教学设计的思考——以学生为中心的设计

赵启铎，舒乐新，何永志，张艳军

《黑龙江教育(理论与实践)》

2016

高效液相法测定头孢拉定胶囊流动相条件的改进

舒乐新，裴靖，赵启铎，宋丽丽，李遇伯

《实验室科学》

2015

教改背景下实验室管理的探讨

舒乐新，赵启铎，苗戎，杨琳

《实验室科学》

2015

Preparation and evaluation of Baicalin-loaded cationic solid lipid nanoparticles conjugated with OX26 for improved delivery across the BBB

Zhi-Dong Liu, Hai-Nan Zhao, Lexin Shu, Yan-Qing Zhang, C. Okeke, Li Zhang, Jia-Wei Li, Nan Li

Drug Development and Industrial Pharmacy

DOI

2015

Tissue distribution study of salvianolic acid B long-circulating liposomes in mice by UPLC-MS/MS determination.

Jia-Xin Pi, Zhi-Dong Liu, Lexin Shu, Lin Li, Ying Wang, Nan Li, Jia-Wei Li

Pakistan Journal of Pharmaceutical Sciences

2014

酸枣仁总黄酮和总皂苷部位制备工艺的稳定性考察

赵启铎，舒乐新，蔡广知

《中国实验方剂学杂志》

2014

均匀设计法优选酸枣仁抗抑郁有效组分配伍研究

赵启铎，舒乐新，高岚

《中国药业》

2013

酸枣仁总皂苷的含量测定

赵启铎，舒乐新

《天津中医药大学学报》

2013

药学文献检索课程教学探讨

赵启铎，舒乐新，邓雁如，牟佳佳，何永志

《中国中医药现代远程教育》

2013

改革生物化学实验教学提高实验教学质量

舒乐新，苗戎，杨琳，赵启铎

《实验室科学》

2012

PEG修饰黄芩苷固体脂质纳米粒的制备

舒乐新，孙精通，刘志东，赵启铎

《时珍国医国药》

2011

丹酚酸B脂质体的制备及其体外释药的研究

马金鹏，舒乐新，刘志东

《中草药》

2011

关于《中药化学》课程教学探讨与实践

赵启铎，舒乐新，何永志，邓雁如，王颖

《中国中医药现代远程教育》

2011

PBL教学法在中药化学实验教学中的应用

赵启铎，何永志，邓雁如，舒乐新，王颖，高璎

《中国中医药现代远程教育》

2011

酸枣仁油对行为绝望小鼠模型的影响

赵启铎，舒乐新，王颖，牟佳佳，宋志国，李金梅

《中国实验方剂学杂志》

2011

酸枣仁总黄酮抗抑郁作用的实验研究

赵启铎，舒乐新，王颖，牟佳佳，宋志国，李金梅

《天津中医药》

2011

Labrasol对利巴韦林角膜透过率的影响

武昊昀，舒乐新，刘志东，殷健，李楠，潘卫三

《沈阳药科大学学报》

2011

硫酸-苯酚法测定槐甘菌质多糖的含量

赵启铎，舒乐新，马琳，崔国红

《宜春学院学报》

2011

酸枣仁总皂苷抗抑郁作用的实验研究

赵启铎，舒乐新，王颖，牟佳佳，宋志国，李金梅

《中南药学》

2011

The effects of Different Penetration Enhancers on Breviscapinun Across the rat Skin in vitro

Lexin Shu

2011

Preparation and evaluation of solid lipid nanoparticles of baicalin for ocular drug delivery system in vitro and in vivo

Zhi-Dong Liu, Xinhua Zhang, Haoyun Wu, Jia-Wei Li, Lexin Shu, R. Liu, Lin Li, Nan Li

Drug Development and Industrial Pharmacy

DOI

2010

3种渗透促进剂对芒果苷离体角膜透过率的影响

刘睿，刘志东，舒乐新，章臣桂，张伯礼

《中国中药杂志》

2010

Labrasol对葛根素角膜透过性的研究

舒乐新，赵启铎，刘志东，李琳，宋西卫，李楠

《天津中医药》

2010

凝聚法制备川芎嗪固体脂质纳米粒

郝存江，饶卫兵，魏丽，舒乐新，刘志东，杨梦婕

《现代生物医学进展》

2010

辛酸癸酸聚乙二醇甘油酯对加替沙星角膜透过性的影响

舒乐新，刘志东，赵启铎，李琳，武昊昀，李楠

《中国新药杂志》

2010

[Effect of three penetration enhancers on corneal permeability of mangiferin in vitro].

Rui Liu, Zhi-Dong Liu, Lexin Shu, Chengui Zhang, Boli Zhang

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

DOI

2010

Preparation of TMP solid lipid nanoparticles by coagulation.

Cun-Jiang Hao, Wei-Bing Rao, Li Wei, An Mengjie, Lexin Shu, Zhi-Dong Liu

2009

消炎止咳浸膏中总皂苷的含量测定

赵启铎，王颖，舒乐新，宋志国，李金梅

《天津中医药大学学报》

2009

Labrasol对兔眼刺激性评价

张欣华，刘志东，张伯礼，舒乐新，高秀梅，柳占彪，张远

《医药导报》

2009

Effects of Labrasol on the corneal drug delivery of baicalin

Zhi-Dong Liu, Xinhua Zhang, Jia-Wei Li, Rui Liu, Lexin Shu, Jun Jin

Drug Delivery

DOI

2009

Determination of total saponins in anti-inflammatory and antasthmatic extractum

Lexin Shu

2008

羟丙基-β-环糊精对黄芩苷角膜透过性研究

张欣华，刘志东，张伯礼，舒乐新，高秀梅

《天津中医药》

精选作品

期刊论文

Rapid Classification and Identification of Chemical Constituents of Chelidonium majus L. Based on UHPLC‐Q‐Exactive Orbitrap MS

Rapid Identification of Chemical Constituents of Zanthoxylum nitidum (Roxb.) DC. by Ultra‐High‐Performance Liquid Chromatography Quadrupole‐Exactive Orbitrap Mass Spectrometry

Systematic Characterization of the In Vitro and In Vivo Chemical Constituents of Shenmai Formula by UHPLC-Orbitrap MS.

Single-nucleus RNA Sequencing and multi-omics reveal Uncaria-derived indole alkaloids induce hepatocyte injury by mediating CAR/PPARα axis.

Schisandrin B Attenuates Doxorubicin-Induced Acute Cardiac Injury through Regulation of Metabolites and Gut Microbiota.

Systematic Characterization of the Chemical Constituents of in Vitro and in Vivo of Astragali Radix-Salvia miltiorrhiza Herb Pair by Ultra-High-Performance-Liquid Chromatography-Orbitrap Mass Spectrometry.

蒽环类药物心脏毒性的中西药防治策略

Chemical composition analysis of Qingyan dropping pills using ultra‐high‐performance liquid chromatography‐quadrupole time‐of‐flight mass spectrometry

Unique metabolomics characteristics for distinguishing cirrhosis related to different liver diseases: A systematic review and meta-analysis.

Rapid identification and determination of chemical components of huai yam based on UPLC-Q-Exactive-MS and fragmentation patterns

Rapid Identification of Chemical Constituents in New Compound Aloe Capsule Based on UPLC-Q-Orbitrap-MS.

Rapid identification of various chemical components in Cinnamomi ramulus by UPLC-Q-Orbitrap-MS.

Rapid classification and identification of chemical components in three different Zanthoxylum species by ultra-high-performance-liquid chromatography quadrupole-orbitrap-mass spectrometry.

UPLC-Q-TOF/MS结合网络药理学和分子对接技术探讨山豆根抗肝癌的药效物质及作用机制

通脉养心丸减轻阿霉素致小鼠急性心脏毒性的作用研究

口服含柴胡制剂治疗部分临床常见病系统评价

暴露评估在中药危害物质限量标准中的方法、应用及展望

仪器分析实验“三点一线”式教学模式探索

Analysis of chemical components of Jianwei Xiaoshi Tablets based on UPLC-Q-Orbitrap-MS technology

Rapid identification of chemical compositions of three species of Schisandra chinensis by ultra-high-performance liquid chromatography quadrupole-orbitrap-mass spectrometry.

Systematic characterization of the chemical constituents in vitro and in vivo of Qianghuo by UPLC-Q-TOF-MS/MS.

A practical method for rapid discrimination of constituents in Psoraleae Fructus by UPLC-Q-Orbitrap MS.

Rapid identification of chemical constituents in Hugan tablets by ultra-performance liquid chromatography-quadrupole-exactive orbitrap mass spectrometry.

Integrating Metabolomics and Network Pharmacology to Explore the Mechanism of Tongmai Yangxin Pills in Ameliorating Doxorubicin-Induced Cardiotoxicity

Pharmacological effects and mechanisms of YiYiFuZi powder in chronic heart disease revealed by metabolomics and network pharmacology

Rapid classification and identification of chemical constituents in Leonurus japonicus Houtt based on UPLC-Q-Orbitrap-MS combined with data post-processing techniques.

中药汤剂治疗蒽环类药物所致心脏毒性的网状Meta分析

中药分析实验藿香正气水中乙醇含量测定探讨

阿霉素急性心脏毒性大鼠造模方法研究

Rapid screening of hepatotoxic components in Uncariae Ramulus Cum Uncis based on "component-target-pathway" network.

Enantioseparation and determination of oxypeucedanin and its application to a stereoselective analysis in Angelica Dahuricae Radix and pharmacokinetic study of rats.

通脉养心丸对阿霉素慢性心脏毒性大鼠的保护作用研究

A New Strategy for the Rapid Identification and Validation of the Direct Targets of Aconitine-Induced Cardiotoxicity

DDDT_A_335461 4649..4664

互联网背景下药物分析混合式教学模式探究

Exploration the Mechanism of Doxorubicin-Induced Heart Failure in Rats by Integration of Proteomics and Metabolomics Data

Integrated Proteomics and Metabolomics Reveal the Mechanism of Nephrotoxicity Induced by Triptolide.

中药化学课程中的一般方法教学设计探讨——以第二章“提取分离”为例

体内药物分析血清中对乙酰氨基酚分析方法的探讨

临床药学专业体内药物分析课程的教学调查与思考

关于教学设计的思考——以学生为中心的设计

高效液相法测定头孢拉定胶囊流动相条件的改进

教改背景下实验室管理的探讨

Preparation and evaluation of Baicalin-loaded cationic solid lipid nanoparticles conjugated with OX26 for improved delivery across the BBB

Tissue distribution study of salvianolic acid B long-circulating liposomes in mice by UPLC-MS/MS determination.

酸枣仁总黄酮和总皂苷部位制备工艺的稳定性考察

均匀设计法优选酸枣仁抗抑郁有效组分配伍研究

酸枣仁总皂苷的含量测定

药学文献检索课程教学探讨

改革生物化学实验教学 提高实验教学质量

PEG修饰黄芩苷固体脂质纳米粒的制备

丹酚酸B脂质体的制备及其体外释药的研究

关于《中药化学》课程教学探讨与实践

PBL教学法在中药化学实验教学中的应用

酸枣仁油对行为绝望小鼠模型的影响

酸枣仁总黄酮抗抑郁作用的实验研究

Labrasol对利巴韦林角膜透过率的影响

硫酸-苯酚法测定槐甘菌质多糖的含量

酸枣仁总皂苷抗抑郁作用的实验研究

The effects of Different Penetration Enhancers on Breviscapinun Across the rat Skin in vitro

Preparation and evaluation of solid lipid nanoparticles of baicalin for ocular drug delivery system in vitro and in vivo

3种渗透促进剂对芒果苷离体角膜透过率的影响

Labrasol对葛根素角膜透过性的研究

凝聚法制备川芎嗪固体脂质纳米粒

辛酸癸酸聚乙二醇甘油酯对加替沙星角膜透过性的影响

[Effect of three penetration enhancers on corneal permeability of mangiferin in vitro].

Preparation of TMP solid lipid nanoparticles by coagulation.

消炎止咳浸膏中总皂苷的含量测定

Labrasol对兔眼刺激性评价

Effects of Labrasol on the corneal drug delivery of baicalin

Determination of total saponins in anti-inflammatory and antasthmatic extractum

羟丙基-β-环糊精对黄芩苷角膜透过性研究

预印本

Rapid identification of three species of Schisandra chinensis based on UPLC-Q-Orbitrap-MS technique and characteristic fragments

改革生物化学实验教学提高实验教学质量