姚武｜郑州大学｜学者主页

2026

C3a-C3ar1 axis mediates macrophage M1 polarization to drive silicosis inflammation and fibrosis

Xuesong Zhang, Hui Fan, Jianxia Cao, Xiaoge Cui, Yan Xie, Jingwen Fan, Xueyang Zhang, Wu Yao, Changfu Hao

Environmental Pollution

2026

Temporal modulation of cuproptosis and autophagy mediates nanographene-driven pulmonary fibrosis progression

Jiarui Xia, Xiaolong Tang, Huijie Shang, Youliang Zhao, Shuqi Li, Ke Yong Tang, Yi Li, Wenzhuo Wu, Qun Xu, Changfu Hao, Wu Yao

Experimental Cell Research

DOI

2025

小鼠硅沉着病发生发展过程中肺部菌群的变化

赵晓航，赵聪聪，唐小翠，杨思思，王娜，姚武

《郑州大学学报(医学版)》

DOI

2025

基于16S rDNA测序的硅沉着病小鼠肺部和肠道菌群特征分析

杨思思，唐小翠，赵晓航，王娜，姚武

《郑州大学学报(医学版)》

DOI

2025

外泌体在听力损失治疗中的研究进展

王冰，焦洁，姚武

《郑州大学学报(医学版)》

DOI

2025

Unveiling Novel Biomarkers: Ferroptosis and m1A in the Progression of Nanographene‐Induced Lung Fibrosis

Jiarui Xia, Wenzhuo Wu, Hui Fan, Xiaolong Tang, Shuqi Li, Ke Tang, Changfu Hao, Qun Jie Xu, Youliang Zhao, Wu Yao

Small

DOI

2025

KLF4/FOXF1 axis alleviates silicosis fibrosis by modulating fibroblast behavior and extracellular matrix remodeling

Xuesong Zhang, Hui Fan, Ge Qin, Bowen Fu, Botao Hu, Jingwen Fan, Youliang Zhao, Yuanmeng Qi, Xueyang Zhang, Wu Yao, Changfu Hao

Journal of Environmental Sciences

DOI

2025

Dysregulation of immune checkpoint LAG3 in mice exposed to silica

Meixiu Duan, Youliang Zhao, Yaqian Qu, Changfu Hao, Wu Yao

Toxicology Letters

DOI

2025

Fra2, a potential therapeutic target for silicosis

Yuanmeng Qi, Jiarui Xia, Xuesong Zhang, Xiaoying Li, Qimeng Li, Zhenzhen Yang, Wu Yao, Changfu Hao, Youliang Zhao

Genes & Diseases

DOI

2025

Innate immune checkpoint SIRPα/CD47 blockade ameliorates silica-induced pulmonary fibrosis by modulating macrophage immunity

Youliang Zhao, Meixiu Duan, Yuanmeng Qi, Jiarui Xia, Changfu Hao, Wu Yao

International Immunopharmacology

DOI

2024

两种职业健康风险模型在铸造作业中矽尘的评估和应用

余其，姚武

《职业卫生与病伤》

2024

噪声和电焊烟尘联合作用与职业性噪声性听力损失关系

王冰，张磊，李雨铮，姚玲莉，樊惠玲，姚武，焦洁

《卫生研究》

2024

苯系物与噪声联合暴露对男工职业性噪声性听力损失的影响

樊惠玲，焦洁，张磊，李雨铮，姚玲莉，王冰，郝长付，姚武

《现代预防医学》

DOI

2024

男性噪声作业工人血糖水平与职业性噪声性听力损失的关系研究

姚玲莉，焦洁，张磊，李雨峥，樊惠玲，王冰，郝长付，姚武

《医药论坛杂志》

2024

PD-L1 upregulation in activated fibroblasts promotes silica particle-induced pulmonary fibrosis

Youliang Zhao, Yaqian Qu, Meixiu Duan, Yuanmeng Qi, Jiarui Xia, Changfu Hao, Wu Yao

International Journal of Biological Macromolecules

DOI

2024

Effect and Mechanism of Action of BMSC-derived Exosomes on Gas Explosion-induced Blast Lung Injury.

Xiaoying Li, Jing He, Meng Deng, Hui Fan, Xiaofei Jin, Xuedan Deng, Wenjie Ren, Sanqiao Yao, Wu Yao, Changfu Hao

PubMed

DOI

2024

The role of the PI3K/AKT/mTOR pathway in mediating PD-L1 upregulation during fibroblast transdifferentiation

Youliang Zhao, Yuanmeng Qi, Jiarui Xia, Meixiu Duan, Changfu Hao, Wu Yao

International Immunopharmacology

DOI

2024

Jun and JunB members of the AP-1 complex are potential therapeutic targets for silicosis

Yuanmeng Qi, Youliang Zhao, Jiarui Xia, Botao Hu, Xiaoying Li, Qimeng Li, Zhenzhen Yang, Wu Yao, Changfu Hao

International Journal of Biological Macromolecules

DOI

2024

FAP expression dynamics and role in silicosis: Insights from epidemiological and experimental models

Xuedan Deng, Zhiwei Cheng, Yiping Li, Meixiu Duan, Jingyi Qi, Changfu Hao, Wu Yao

Environmental Pollution

DOI

2024

FOXF1 reverses lung fibroblasts transdifferentiation via inhibiting TGF-β/SMAD2/3 pathway in silica-induced pulmonary fibrosis

Botao Hu, Xuesong Zhang, Hui Fan, Xiaofei Jin, Yuanmeng Qi, Ruimin Liu, Xiaoying Li, Meixiu Duan, Chengpeng Zhang, Shiyu Li, Wu Yao, Changfu Hao

International Immunopharmacology

DOI

2024

Bioinformatics-based dynamics of cuproptosis -related indicators in experimental silicosis

Jiarui Xia, Chenchen Wu, Xiaofei Jin, Mingcui Ding, Chengpeng Zhang, Guangjie Hou, Changfu Hao, Wu Yao

Ecotoxicology and Environmental Safety

DOI

2024

Exposure to micron-grade silica particles triggers pulmonary fibrosis through cell-to-cell delivery of exosomal miR-107

Jiarui Xia, Di Wang, Wei Guo, Yangqing Pei, Lin Zhang, Lei Bao, Yiping Li, Yaqian Qu, Youliang Zhao, Changfu Hao, Wu Yao

International Journal of Biological Macromolecules

DOI

2024

Manganese accumulation in red blood cells as a biomarker of manganese exposure and neurotoxicity

Xuedan Deng, Yonghua Guo, Xiaofei Jin, Huifang Si, Kai Dai, Meng Deng, Jing He, Changfu Hao, Wu Yao

NeuroToxicology

DOI

2024

Time-series transcriptome analysis mapping pulmonary immune checkpoint atlas of experimental silicosis

Youliang Zhao, Yuanmeng Qi, Meixiu Duan, Changfu Hao, Wu Yao

Genes & Diseases

DOI

2024

Corrigendum to “A2aR inhibits fibrosis and the EMT process in silicosis by regulating Wnt/β-catenin pathway” [Ecotoxicol. Environ. Saf. 249 (2023) 114410]

Yangyang Tian, Jiarui Xia, Guo Yang, Chao Richard Li, Yuanmeng Qi, Kai Dai, Chenchen Wu, Yonghua Guo, Wu Yao, Changfu Hao

Ecotoxicology and Environmental Safety

DOI

2024

Expression levels of key immune indicators and immune checkpoints in manganese-exposed rats

Yuanmeng Qi, Huifang Si, Xiaofei Jin, Yonghua Guo, Jiarui Xia, Jing He, Xuedan Deng, Meng Deng, Wu Yao, Changfu Hao

Ecotoxicology and Environmental Safety

DOI

2023

两种评估模型在某碳纤维厂职业健康风险评估中的应用

姬婧云，周文慧，姚武

《职业卫生与应急救援》

2023

Changes in serum TIM-3 and complement C3 expression in workers due to Mn exposure

Yuanmeng Qi, Huifang Si, Xiaofei Jin, Yonghua Guo, Jiarui Xia, Jing He, Xuedan Deng, Meng Deng, Wu Yao, Changfu Hao

Frontiers in Public Health

DOI

2023

The role of N6-methyladenosine methylation in PAHs-induced cancers

Yujie Wei, Xiaona Guo, Lifeng Li, Wenhua Xue, Longhao Wang, Chengxin Chen, Shilong Sun, Yaqi Yang, Wu Yao, Wei Wang, Jie Zhao, Xiaoran Duan

Environmental Science and Pollution Research

DOI

2023

Silica-exposed macrophages-secreted exosomal miR125a-5p induces Th1/Th2 and Treg/Th17 cell imbalance and promotes fibroblast transdifferentiation

Mingcui Ding, Chengpeng Zhang, Wei Wang, Pengpeng Wang, Yangqing Pei, Na Wang, Shan Huang, Changfu Hao, Wu Yao

Ecotoxicology and Environmental Safety

DOI

2023

GGA (geranylgeranylacetone) ameliorates bleomycin-induced lung inflammation and pulmonary fibrosis by inhibiting apoptosis and oxidative stress

Rong Zhou, Chaomei Jin, Linlin Jiao, Siyu Zhang, Mei Tian, Jiamin Liu, Songtai Yang, Wu Yao, Fang Zhou

Molecular Biology Reports

DOI

2023

Benchmark Dose Assessment for Coke Oven Emissions-Induced Mitochondrial DNA Copy Number Damage Effects.

Zhao Fan Yan, Zhi Guang Gu, Ya Hui Fan, Xin Ling Li, Ze Ming Niu, Xiao Ran Duan, Manthar Ali Mallah, Qiao Zhang, Yong Li Yang, Wu Yao, Wei Wang

PubMed

DOI

2023

Geranylgeranylacetone, an inducer of heat shock protein 70, attenuates pulmonary fibrosis via inhibiting NF-κB/NOX4/ROS signalling pathway in vitro and in vivo

Rong Zhou, Chaomei Jin, Linlin Jiao, Siyu Zhang, Mei Tian, Jiamin Liu, Songtai Yang, Wu Yao, Fang Zhou

Chemico-Biological Interactions

DOI

2023

Mitochondrial folate pathway regulates myofibroblast differentiation and silica-induced pulmonary fibrosis

Yaqian Qu, Ruonan Zhai, Dandan Wang, Zheng Wang, Guangjie Hou, Chenchen Wu, Meian Tang, Xiongbin Xiao, Jie Jiao, Yue Ba, Fang Zhou, Jian Qiu, Wu Yao

Journal of Translational Medicine

DOI

2023

PD-1/PD-L1 axis in organ fibrosis

Youliang Zhao, Yaqian Qu, Changfu Hao, Wu Yao

Frontiers in Immunology

DOI

2023

Chain-mediating effect of interaction between telomeres and mitochondria under oxidative stress in coke oven workers

Zhiguang Gu, Zeming Niu, Zhaofan Yan, Yahui Fan, Jing Sun, Xiangkai Zhao, Xiaoran Duan, Wu Yao, Yongli Yang, Wei Wang

Environmental Pollution

DOI

2023

Benchmark dose estimation based on oxidative damage in Chinese workers exposed to benzene series compounds

Yonghua Guo, Xuedan Deng, Kai Dai, Meng Deng, Jing He, Huifang Si, Xiao Min Xu, Zhuoya Niu, Chen Wang, Wu Yao, Changfu Hao

Environmental Toxicology and Pharmacology

DOI

2023

EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS

Meng Deng, Jing He, Changfu Hao, Yonghua Guo, Huifang Si, Xuedan Deng, Chengpeng Zhang, Shiyu Li, Sanqiao Yao, Wenjie Ren, Wu Yao

Shock

DOI

2023

Proteomic Analysis Revealed the Involvement of Autophagy in Rat Acute Lung Injuries Caused by Gas Explosion Based on a Data-Independent Acquisition Strategy.

Shan Hong, Chunjie Ding, Qiang Zhou, Yun Zhe Sun, Miao Zhang, Ning Li, Xin Wen Dong, Yi Guan, Lin Zhang, Lin Qiang Tian, Jia Cao, Wu Yao, Wen Jie Ren, Sanqiao Yao

PubMed

DOI

2023

HMGB1 coordinates with Brahma-related gene 1 to promote epithelial-mesenchymal transition via the PI3K/Akt/mTOR pathway in BEAS-2B cells

Xuedan Deng, Zhuoya Niu, Changfu Hao, Jisong Lin, Wu Yao

Experimental Cell Research

DOI

2023

Effect and interaction of TNKS genetic polymorphisms and environmental factors on telomere damage in COEs-exposure workers

Xiaoran Duan, Tao Huang, Daping Zhang, Yujie Wei, Lifeng Li, Wu Yao, Liuxin Cui, Xiaoshan Zhou, Yongli Yang, Wei Wang, Jie Zhao

Ecotoxicology and Environmental Safety

DOI

2023

The diagnostic value of circulating abnormal cells in early lung cancer.

Hui Meng, Wu Yao, Manman Nan, Fu-Guang Zhou, Wenyan Song, Yizhen Li, Yuhui Yin, Yi Ding

PubMed

2022

NOX2抑制剂gp91 ds-tat缓解瓦斯爆炸引起的大鼠肺损伤

张淼，孙蕴哲，曹佳，姚武，任文杰，姚三巧

《职业卫生与应急救援》

2022

A2aR inhibits fibrosis and the EMT process in silicosis by regulating Wnt/β-catenin pathway

Yangyang Tian, Jiarui Xia, Guo Yang, Chao Li, Yuanmeng Qi, Kai Dai, Chenchen Wu, Yonghua Guo, Wu Yao, Changfu Hao

Ecotoxicology and Environmental Safety

DOI

2022

MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells

Jiarui Xia, Yangyang Tian, Zheng Shao, Chao Li, Mingcui Ding, Yuanmeng Qi, Xiao Xu, Kai Dai, Chenchen Wu, Wu Yao, Changfu Hao

Ecotoxicology and Environmental Safety

DOI

2022

Exosomal miR-125a-5p regulates T lymphocyte subsets to promote silica-induced pulmonary fibrosis by targeting TRAF6

Mingcui Ding, Yangqing Pei, Chengpeng Zhang, Yuanmeng Qi, Jiarui Xia, Changfu Hao, Wu Yao

Ecotoxicology and Environmental Safety

DOI

2022

Expression level and function analysis of serum miRNAs in workers with occupational exposure to benzene series

Kai Dai, Chen Wang, Wu Yao, Changfu Hao

Chemosphere

DOI

2022

Detection and analysis of lung microbiota in mice with lung cancer lacking the NLRP3 gene

Xinyan Li, Congcong Zhao, Chao Li, Mengmeng Zhang, Yuanchen Xie, Feifei Feng, Wu Yao, Na Wang

Biochemical and Biophysical Research Communications

DOI

2022

Lysophosphatidylcholine acyltransferase 1 alleviates silica-induced pulmonary fibrosis by modulating lipid metabolism

Xuedan Deng, Changfu Hao, Yiping Li, Yonghua Guo, Huifang Si, Jing He, Meng Deng, Zhuoya Niu, Chen Wang, Xiao Xu, Kai Dai, Wu Yao

Biomedicine & Pharmacotherapy

DOI

2022

Glycyrrhizic Acid Attenuates Pulmonary Fibrosis of Silicosis by Inhibiting the Interaction between HMGB1 and BRG1 through PI3K/Akt/mTOR Pathway

Zhuoya Niu, Jisong Lin, Changfu Hao, Xiao Xu, Chen Wang, Kai Dai, Xuedan Deng, Meng Deng, Yonghua Guo, Wu Yao

International Journal of Environmental Research and Public Health

DOI

2022

Occupational Low-Dose Radiation Affects the Expression of Immune Checkpoint of Medical Radiologists

Chen Wang, Changfu Hao, Kai Dai, Yuzheng Li, Jie Jiao, Zhuoya Niu, Xiao Xu, Xuedan Deng, Jing He, Wu Yao

International Journal of Environmental Research and Public Health

DOI

2022

Inhibition of HIF-1α Attenuates Silica-Induced Pulmonary Fibrosis

Xiao Xu, Yiping Li, Zhuoya Niu, Jiarui Xia, Kai Dai, Chen Wang, Wu Yao, Yonghua Guo, Xuedan Deng, Jing He, Meng Deng, Huifang Si, Changfu Hao

International Journal of Environmental Research and Public Health

DOI

2022

Dendritic cells activated by cimetidine induce Th1/Th17 polarization in vitro and in vivo

Yaqian Qu, Lei Bao, Youliang Zhao, Yiping Li, Mingcui Ding, Changfu Hao, Wu Yao

Toxicology in Vitro

DOI

2022

Prediction of lung cancer using gene expression and deep learning with KL divergence gene selection

Suli Liu, Wu Yao

BMC Bioinformatics

DOI

2022

LncRNA UCA1 regulates silicosis-related lung epithelial cell-to-mesenchymal transition through competitive adsorption of miR-204-5p

Guo Yang, Yangyang Tian, Chao Richard Li, Jiarui Xia, Yuanmeng Qi, Wu Yao, Changfu Hao

Toxicology and Applied Pharmacology

DOI

2022

Mechanism of LncRNA XIST/ miR-101–3p/ZEB1 axis in EMT associated with silicosis

Chao Li, Jiarui Xia, Wu Yao, Guo Yang, Yangyang Tian, Yuanmeng Qi, Changfu Hao

Toxicology Letters

DOI

2022

PD-1/PD-L1 inhibitor ameliorates silica-induced pulmonary fibrosis by maintaining systemic immune homeostasis

Youliang Zhao, Changfu Hao, Meng Li, Yaqian Qu, Yonghua Guo, Xuedan Deng, Huifang Si, Wu Yao

Biomedicine & Pharmacotherapy

DOI

2022

Epigenetic Changes and Functions in Pneumoconiosis

Yiping Li, Zhiwei Cheng, Hui Fan, Changfu Hao, Wu Yao

Oxidative Medicine and Cellular Longevity

DOI

2021

A549细胞上皮-间质转分化中差异表达基因的生物信息学分析

杨果，李超，姚武，夏佳蕊，祁远梦，郝长付

《环境与职业医学》

2021

矽肺大鼠肺组织差异蛋白筛选与质谱分析

刘素娜，郝长付，暴磊，赵德华，王丽雯，姚武

《郑州大学学报(医学版)》

DOI

2021

NF-κB/NOX1信号通路在TNF-α诱导A549细胞凋亡中的作用

周舫，史凤显，牛淑，翟若南，马铭泽，李珂，王航，许春艳，周蓉，姚武

《中国职业医学》

2021

尘肺病患者血清差异表达miRNAs筛选与生物信息学分析

杨果，祁远梦，杨培琰，李超，魏静静，姚武，郝长付

《中国职业医学》

2021

热休克蛋白70对人肺腺癌A549细胞上皮间质转化的影响

马铭泽，史凤显，翟若南，王航，李珂，许春艳，牛淑，姚武，周舫

《郑州大学学报(医学版)》

DOI

2021

miR-107在TGF-β诱导的NIH-3T3细胞转分化中的作用

裴阳晴，丁明翠，王迪，郝长付，姚武

《郑州大学学报(医学版)》

DOI

2021

Influence of Silica Exposure for Lung Silicosis Rat

Jie Jiao, Li Li, Wu Yao, Weidong Qin, Changfu Hao, Lingeng Lu

Disease Markers

DOI

2021

Research progress on the mechanism of ferroptosis and its clinical application

Jiarui Xia, Huifang Si, Wu Yao, Chao Li, Yang Guo, Yangyang Tian, Changfu Hao

Experimental Cell Research

DOI

2021

PPARγ/LXRα axis mediated phenotypic plasticity of lung fibroblasts in silica-induced experimental silicosis

Yuanmeng Qi, Haichen Zhang, Hui Fan, Xinyu Wang, Ahui Zhao, Yangyang Tian, Guo Yang, Chao Richard Li, Jingjing Wei, Wu Yao, Changfu Hao

Environmental Pollution

DOI

2021

Relationship between TERT Polymorphism and Telomere Length in Workers Exposed to Omethoate.

Shuai Cheng, Bin Liu, Zhi Feng Guo, Xiao Ran Duan, Su Xiang Liu, Lei Li, Wu Yao, Yong Li Yang, Wei Wang

PubMed

DOI

2021

Genetic variants in telomerase-associated protein 1 are associated with telomere damage in PAH-exposed workers

Xiaoran Duan, Hongmei Wang, Yongli Yang, Pengpeng Wang, Hui Zhang, Bin Liu, Wan Wei, Wu Yao, Xiaoshan Zhou, Jie Zhao, Wei Wang

Ecotoxicology and Environmental Safety

DOI

2021

Mesenchymal stem cells ameliorate silica‐induced pulmonary fibrosis by inhibition of inflammation and epithelial‐mesenchymal transition

Jingjing Wei, Qiuyan Zhao, Guo Yang, Ruoxuan Huang, Chao Richard Li, Yuanmeng Qi, Changfu Hao, Wu Yao

Journal of Cellular and Molecular Medicine

DOI

2021

In vitro co-culture model of human monocyte-derived dendritic cells and T cells to evaluate the sensitization of dinitrochlorobenzene

Lei Bao, Changfu Hao, Juan Wang, Feifei Guo, Zihan Geng, Di Wang, Youliang Zhao, Yiping Li, Wu Yao

Ecotoxicology and Environmental Safety

DOI

2021

SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation

Ruoxuan Huang, Changfu Hao, Di Wang, Qiuyan Zhao, Chao Richard Li, Chen Wang, Wu Yao

Toxicology and Applied Pharmacology

DOI

2021

Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats

Qiuyan Zhao, Changfu Hao, Jingjing Wei, Ruoxuan Huang, Chao Richard Li, Wu Yao

Ecotoxicology and Environmental Safety

DOI

2021

Genetic polymorphisms of metabolic enzyme genes associated with leukocyte mitochondrial DNA copy number in PAHs exposure workers

Xinling Li, Xiaoran Duan, Hui Zhang, Mingcui Ding, Yanbin Wang, Yongli Yang, Wu Yao, 夏昭林, Xiaoshan Zhou, Wei Wang

Cancer Reports

DOI

2021

TGF-β promote epithelial-mesenchymal transition via NF‐κB/NOX4/ROS signal pathway in lung cancer cells

Mingze Ma, Fengxian Shi, Ruonan Zhai, Hang Wang, Ke Li, Chunyan Xu, Wu Yao, Fang Zhou

Molecular Biology Reports

DOI

2021

Overexpression of heat shock protein 70 inhibits epithelial-mesenchymal transition and cell migration induced by transforming growth factor-β in A549 cells

Fengxian Shi, Mingze Ma, Ruonan Zhai, Yanan Ren, Ke Li, Hang Wang, Chunyan Xu, Xiaowen Huang, Na Wang, Fang Zhou, Wu Yao

Cell Stress and Chaperones

DOI

2021

Estimations of benchmark dose for urinary metabolites of coke oven emissions among workers

Kaili Zou, Sihua Wang, Pengpeng Wang, Xiaoran Duan, Yongli Yang, Mahdieh Danesh Yazdi, Jennifer Stowell, Yanbin Wang, Wu Yao, Wei Wang

Environmental Pollution

DOI

2020

转化生长因子-β1致肺成纤维细胞转分化过程中差异表达基因的筛选和验证

金路恒，杨培琰，赵阿会，田志鹏，姚武，翟若南，郝长付

《环境与职业医学》

DOI

2020

新冠肺炎疫情冲击下对职业卫生与职业医学课程教学模式的思考

郝长付，姚武，周舫，王威，王娜，袁金涛，翟若南

《河南医学高等专科学校学报》

DOI

2020

Association between genetic polymorphisms of telomere pathway genes and hydrogen peroxide level in omethoate exposure workers

Xiaoshan Zhou, Xinling Li, Wan Wei, Xiaoran Duan, Hui Zhang, Mingcui Ding, Wu Yao, Qi Wang, Wei Wang, Yongli Yang

Environmental Toxicology and Pharmacology

DOI

2020

Benchmark dose estimation for coke oven emissions based on oxidative damage in Chinese exposed workers

K. Zou, P. Wang, Xiaoran Duan, Yongli Yang, Huifang Zhang, Shumiao Wang, Liuhua Shi, Y. Wang, Wu Yao, W. Wang

ISEE Conference Abstracts

DOI

2020

Folate and macrophage folate receptor-β in idiopathic pulmonary fibrosis disease: the potential therapeutic target?

Yaqian Qu, Changfu Hao, Ruonan Zhai, Wu Yao

Biomedicine & Pharmacotherapy

DOI

2020

Transcriptome analysis reveals a protective role of liver X receptor alpha against silica particle-induced experimental silicosis

Wu Yao, Peiyan Yang, Yuanmeng Qi, Luheng Jin, Ahui Zhao, Mingcui Ding, Di Wang, Yiping Li, Changfu Hao

The Science of The Total Environment

DOI

2020

Benchmark dose estimation for coke oven emissions based on oxidative damage in Chinese exposed workers

Kaili Zou, Pengpeng Wang, Xiaoran Duan, Yongli Yang, Hui Zhang, Sihua Wang, Liuhua Shi, Yanbin Wang, Wu Yao, Wei Wang

Ecotoxicology and Environmental Safety

DOI

2020

High-Dose Cyclophosphamide Administration Orchestrates Phenotypic and Functional Alterations of Immature Dendritic Cells and Regulates Th Cell Polarization

Lei Bao, Changfu Hao, Juan Wang, Di Wang, Youliang Zhao, Yiping Li, Wu Yao

Frontiers in Pharmacology

DOI

2020

Human monocyte-derived dendritic cells as an in vitro alternative model cell to evaluate the immunotoxicity of 2, 4-Dinitrochlorobenzene

Wu Yao, Mingcui Ding, Lei Bao, Youliang Zhao, Di Wang, Yiping Li, Yaqian Qu, Changfu Hao

Toxicology Letters

DOI

2020

Silica particles disorganize the polarization of pulmonary macrophages in mice

Youliang Zhao, Changfu Hao, Lei Bao, Di Wang, Yiping Li, Yaqian Qu, Mingcui Ding, Ahui Zhao, Wu Yao

Ecotoxicology and Environmental Safety

DOI

2020

Effect of TRF1 rs3863242 polymorphism on telomere length in omethoate-exposed workers

Xiaoshan Zhou, Wan Wei, Xiaoran Duan, Hui Zhang, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Mingcui Ding, Suxiang Liu, Lei Li, Wu Yao, Qi Wang, Reuben Mensah Acquaye, Haiyong Liang, Wei Wang, Yongli Yang

Journal of Environmental Science and Health Part B

DOI

2020

Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation

Di Wang, Changfu Hao, Lin Zhang, Jianhui Zhang, Suna Liu, Yiping Li, Yaqian Qu, Youliang Zhao, Ruoxuan Huang, Jingjing Wei, Wu Yao

Ecotoxicology and Environmental Safety

DOI

2020

Identification of Three Differentially Expressed miRNAs as Potential Biomarkers for Lung Adenocarcinoma Prognosis

Wei Wang, Bin Liu, Xiaoran Duan, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Mingcui Ding, Qiao Zhang, Feifei Feng, Yongjun Wu, Wu Yao, Qi Wang, Yongli Yang

Combinatorial Chemistry & High Throughput Screening

DOI

2020

Dose-related telomere damage associated with the genetic polymorphisms of cGAS/STING signaling pathway in the workers exposed by PAHs

Xiaoran Duan, Yongli Yang, Sihua Wang, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Mingcui Ding, Hui Zhang, Bin Liu, Wan Wei, Wu Yao, Liuxin Cui, Xiaoshan Zhou, Wei Wang

Environmental Pollution

DOI

2019

外泌体miR-125a-5p对NIH/3T3细胞增殖和凋亡的影响

张建会，王永星，郝长付，于兴浩，黄婼旋，魏静静，杨果，姚武

《环境与职业医学》

2019

基于3种细胞因子的尘肺病筛查支持向量机模型的建立

常伟，丁明翠，焦洁，王威，姚武

《郑州大学学报(医学版)》

DOI

2019

二氧化硅致A549细胞损伤差异基因的生物信息学分析

赵阿会，樊慧，杨培琰，赵有亮，金路恒，姚武，郝长付

《中国职业医学》

2019

我国2001—2017年尘肺病研究热点区域分析

于兴浩，樊慧，王永星，暴磊，王迪，姚武，画宝勇，郝长付

《中国职业医学》

2019

NOX1与NF-κB对TNF-α诱导A549细胞氧化损伤的影响

周舫，任亚南，王娜，翟若南，夏艳秋，薛腾，张恺，姚武

《中国职业医学》

2019

TGF-β1致MRC-5细胞转分化的差异microRNAs表达分析

杨培琰，赵阿会，金路恒，赵有亮，于兴浩，张建会，翟若南，郝长付，姚武

《中国职业医学》

2019

医学视频教学在预防医学专业研究生中关注度的调查分析

冯斐斐，陈晓慧，张鹏，刘欣欣，王娜，王威，徐玉宝，姚武，张巧

《河南医学高等专科学校学报》

DOI

2019

Polycyclic aromatic hydrocarbon exposure, miRNA genetic variations, and associated leukocyte mitochondrial DNA copy number: A cross-sectional study in China

Xiaoran Duan, Yongli Yang, Hui Zhang, Bin Liu, Wan Wei, Liuya Wang, Changqing Sun, Wu Yao, Liuxin Cui, Xiaoshan Zhou, Wei Wang

Chemosphere

DOI

2019

Effects of polycyclic aromatic hydrocarbon exposure and miRNA variations on peripheral blood leukocyte DNA telomere length: A cross-sectional study in Henan Province, China

Xiaoran Duan, Daping Zhang, Sihua Wang, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Mingcui Ding, Hui Zhang, Bin Liu, Wan Wei, Reuben Mensah Acquaye, Wu Yao, Liuxin Cui, Xiaoshan Zhou, Wei Wang, Yongli Yang

The Science of The Total Environment

DOI

2019

The association between polymorphisms in tankyrase gene and telomere length in omethoate–exposed workers

Yongli Yang, Jiebing Tan, Xiaoran Duan, Hui Zhang, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Mingcui Ding, Suxiang Liu, Lei Li, Haiyong Liang, Wu Yao, Wei Wang, Xiaoshan Zhou

Chemosphere

DOI

2019

Telomere length in workers was effected by omethoate exposure and interaction between smoking and p21 polymorphisms

Wei Wang, Bin Liu, Xiaoran Duan, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Mingcui Ding, Suxiang Liu, Lei Li, Junling Liu, Lixia Tang, Xinhua Niu, Yuhong Zhang, Guoyu Li, Wu Yao, Yongli Yang

Journal of Environmental Science and Health Part B

DOI

2019

Benchmark dose assessment for coke oven emissions-induced telomere length effects in occupationally exposed workers in China

Wei Wang, Pengpeng Wang, Sihua Wang, Xiaoran Duan, Tuanwei Wang, Xiaolei Feng, Lei Li, Yuhong Zhang, Guo-Yu Li, Junfeng Zhao, Leike Li, Yanbin Wang, Zhen Yan, Feifei Feng, Xiaoshan Zhou, Wu Yao, Yawei Zhang, Yongli Yang

Ecotoxicology and Environmental Safety

DOI

2019

Effects of cyclophosphamide on the phenotypes and functions of THP-1 cells

Youliang Zhao, Changfu Hao, Ruonan Zhai, Lei Bao, Di Wang, Yiping Li, Xinghao Yu, Ruoxuan Huang, Wu Yao

Environmental Toxicology and Pharmacology

DOI

2019

The interaction effects of coke oven emissions exposure and metabolic enzyme Gene variants on total antioxidant capacity of workers

Hui Zhang, Sihua Wang, Xiaoran Duan, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Mingcui Ding, Wei Wang, Xiaoshan Zhou, Wu Yao, Yongli Yang

Environmental Toxicology and Pharmacology

DOI

2019

Genetic polymorphisms, mRNA expression levels of telomere-binding proteins, and associates with telomere damage in PAHs–Exposure workers

Xiaoran Duan, Yongli Yang, Daping Zhang, Sihua Wang, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Mingcui Ding, Hui Zhang, Bin Liu, Wan Wei, Wu Yao, Liuxin Cui, Xiaoshan Zhou, Wei Wang

Chemosphere

DOI

2019

Silica Particles Mediate Phenotypic and Functional Alteration of Dendritic Cells and Induce Th2 Cell Polarization

Suna Liu, Changfu Hao, Lei Bao, Dehua Zhao, Hongyi Zhang, Jianyong Hou, Di Wang, Huiting Chen, Feifei Feng, Wu Yao

Frontiers in Immunology

DOI

2019

NLRP3 deletion inhibits inflammation-driven mouse lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide

Li Huang, Shuyin Duan, Hua Shao, Aihua Zhang, Shuang Chen, Peng Zhang, Na Wang, Wei Wang, Yongjun Wu, Jing Wang, Hong Liu, Wu Yao, Qiao Zhang, Feifei Feng

Respiratory Research

DOI

2019

Association of genetic polymorphisms of miR-145 gene with telomere length in omethoate-exposed workers

Wei Wang, Hui Zhang, Xiaoran Duan, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Mingcui Ding, Xiaoshan Zhou, Suxiang Liu, Lei Li, Junling Liu, Lixia Tang, Xinhua Niu, Yuhong Zhang, Guoyu Li, Wu Yao, Yongli Yang

Ecotoxicology and Environmental Safety

DOI

2019

Diagnostic Value of Plasma MicroRNAs for Lung Cancer Using Support Vector Machine Model

Wei Wang, Mingcui Ding, Xiaoran Duan, Xiaolei Feng, Pengpeng Wang, Qingfeng Jiang, Zhe Cheng, Wenjuan Zhang, Songcheng Yu, Wu Yao, Liuxin Cui, Yongjun Wu, Feifei Feng, Yongli Yang

Journal of Cancer

DOI

2019

miR-let-7d attenuates EMT by targeting HMGA2 in silica-induced pulmonary fibrosis

Xinghao Yu, Ruonan Zhai, Hua Baoyong, Lei Bao, Di Wang, Yiping Li, Wu Yao, Hui Fan, Changfu Hao

RSC Advances

DOI

2018

TGF-β1致人胚肺成纤维细胞转分化差异基因的生物信息学分析

岳中正，暴磊，王迪，张淼，李一平，于兴浩，曲雅倩，张建会，姚武，郝长付

《中国职业医学》

2018

1070 Contribution of bone marrow-derived fibrocytes to silicosis

Juan Li, Wu Yao, Lei Bao, Huiting Chen, Zhongzheng Yue, Yiping Li, Miao Zhang, Jianhui Zhang, Xinghao Yu, Yaqian Qu, Sanqiao Yao, Weidong Wu, Changfu Hao

DOI

2018

Downregulation of exosomal let-7a-5p in dust exposed- workers contributes to lung cancer development

Lin Zhang, Changfu Hao, Ruonan Zhai, Di Wang, Jianhui Zhang, Lei Bao, Yiping Li, Wu Yao

Respiratory Research

DOI

2018

Telomere Length in Workers Was Effected by Omethoate Exposure, GSTM1 Deletion, Interaction Between Smoking and GSTP1 Polymorphisms

Wei Wang, Hui Zhang, Xiaoran Duan, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Mingcui Ding, Suxiang Liu, Lei Li, Junling Liu, Lixia Tang, Xinhua Niu, Yuhong Zhang, Guoyu Li, Wu Yao, Yongli Yang

Journal of Occupational and Environmental Medicine

DOI

2018

Association of genetic polymorphisms of telomere binding proteins with cholinesterase activity in omethoate-exposed workers

Mingcui Ding, Yongli Yang, Xiaoran Duan, Sihua Wang, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Suxiang Liu, Lei Li, Junling Liu, Lixia Tang, Xinhua Niu, Yuhong Zhang, Guo-Yu Li, Wu Yao, Liuxin Cui, Wei Wang

Ecotoxicology and Environmental Safety

DOI

2018

Interaction between polymorphisms in cell-cycle genes and environmental factors in regulating cholinesterase activity in people with exposure to omethoate

Xiaoran Duan, Yongli Yang, Sihua Wang, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Wu Yao, Liuxin Cui, Wei Wang

Royal Society Open Science

DOI

2018

The Role of Fibrocyte in the Pathogenesis of Silicosis.

Juan Li, Wu Yao, Jian Yong Hou, Lin Zhang, Lei Bao, Hui Ting Chen, Di Wang, Zhong Zheng Yue, Yi Ping Li, Miao Zhang, Xing Hao Yu, Jian Hui Zhang, Yaqian Qu, Chang Fu Hao

PubMed

DOI

2018

Identification of Exosomal miRNAs in Rats With Pulmonary Neutrophilic Inflammation Induced by Zinc Oxide Nanoparticles

Yamei Qiao, Xiao Hui Liang, Yingjie Yan, Ya‐Ke Lu, Di Zhang, Wu Yao, Weidong Wu, Zhen Yan

Frontiers in Physiology

DOI

2018

Exosomal miRNA Profiling to Identify Nanoparticle Phagocytic Mechanisms

Lin Zhang, Changfu Hao, Sanqiao Yao, Rong Tang, Wei Guo, Hongbin Cong, Jiangfeng Li, Lei Bao, Di Wang, Yiping Li, Xinghao Yu, Shuyin Duan, Wu Yao

Small

DOI

2018

Dendritic cells trigger imbalance of Th1/Th2 cells in silica dust exposure rat model via MHC-II, CD80, CD86 and IL-12

Lei Bao, Changfu Hao, Suna Liu, Lin Zhang, Juan Wang, Di Wang, Yiping Li, Wu Yao

RSC Advances

DOI

2018

Up-regulation of exosomal miR-125a in pneumoconiosis inhibits lung cancer development by suppressing expressions of EZH2 and hnRNPK

Lin Zhang, Jiangfeng Li, Changfu Hao, Wei Guo, Di Wang, Jianhui Zhang, Youliang Zhao, Shuyin Duan, Wu Yao

RSC Advances

DOI

2018

Correction: Up-regulation of exosomal miR-125a in pneumoconiosis inhibits lung cancer development by suppressing expressions of EZH2 and hnRNPK

Lin Zhang, Jiangfeng Li, Changfu Hao, Wei Guo, Di Wang, Jianhui Zhang, Youliang Zhao, Shuyin Duan, Wu Yao

RSC Advances

DOI

2017

纳米氧化锌对A549细胞脂质过氧化作用

梁肖，刘文佳，闫英洁，张迪，俞巧玲，乔亚梅，周舫，姚武，燕贞

《中国职业医学》

2017

特发性肺纤维化发生发展过程中miR-29的作用及上下游信号通路研究进展

岳中正，李娟，暴磊，陈慧婷，姚武，郝长付

《山东医药》

2017

非吞噬细胞氧化酶4在转化生长因子-β诱导A549细胞迁移中的作用

薛腾，徐小艳，夏艳秋，任亚南，燕贞，姚武，周舫

《卫生研究》

2017

游离二氧化硅诱导肺泡Ⅱ型上皮细胞转化机制

陈慧婷，樊慧，姚武，李娟，岳中正，李一平，张淼，郝长付

《中国职业医学》

2017

Crystalline Silica Promotes Rat Fibrocyte Differentiation in Vitro, and Fibrocytes Participate in Silicosis in Vivo.

Juan Li, Wu Yao, Jian Yong Hou, Lin Zhang, Lei Bao, Hui Ting Chen, Di Wang, Zhong Zheng Yue, Yi Ping Li, Miao Zhang, Chang Fu Hao

PubMed

DOI

2017

Cross-sectional associations between genetic polymorphisms in metabolic enzymes and longer leukocyte telomere length induced by omethoate

Xiaoran Duan, Yongli Yang, Sihua Wang, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Suxiang Liu, Lei Li, Guoyu Li, Wu Yao, Liuxin Cui, Wei Wang

Oncotarget

DOI

2017

Detection of the Single Nucleotide Polymorphism at Position rs2735940 in the Human Telomerase Reverse Transcriptase Gene by the Introduction of a New Restriction Enzyme Site for the PCR-RFLP Assay.

Sihua Wang, Mingcui Ding, Xiaoran Duan, Tuanwei Wang, Xiaolei Feng, Pengpeng Wang, Wu Yao, Yongjun Wu, Zhen Yan, Feifei Feng, Songcheng Yu, Wei Wang

PubMed

2017

Changes in the expression of genes involved in cell cycle regulation and the relative telomere length in the process of canceration induced by omethoate

Xiaoran Duan, Yongli Yang, Sihua Wang, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Suxiang Liu, Lei Li, Wu Yao, Liuxin Cui, Wei Wang

Tumor Biology

DOI

2017

Bioinformatics methods for identifying differentially expressed genes and signaling pathways in nano-silica stimulated macrophages

Lin Zhang, Changfu Hao, Juan Li, Yaqian Qu, Lei Bao, Yiping Li, Zhongzheng Yue, Miao Zhang, Xinghao Yu, Huiting Chen, Jianhui Zhang, Di Wang, Wu Yao

Tumor Biology

DOI

2017

Genome-wide DNA methylation analysis in lung fibroblasts co-cultured with silica-exposed alveolar macrophages

Juan Li, Wu Yao, Lin Zhang, Lei Bao, Huiting Chen, Di Wang, Zhongzheng Yue, Yiping Li, Miao Zhang, Changfu Hao

Respiratory Research

DOI

2017

Coal tar pitch extract could induce chromosomal instability of human bronchial epithelial cells mediated by spindle checkpoint-related proteins

Peng Zhang, Zhitao Li, Na Wang, Guangcai Duan, Wei Wang, Yanming Feng, Yong Xiang Zhao, Lixia Wang, Hansong Zhu, Qiao Zhang, Xiaozhuan Liu, Weidong Wu, Yongjun Wu, Wu Yao, Jing Wang, WU Yi-ming, Feifei Feng

Oncotarget

DOI

2016

实验性矽肺大鼠肺组织中Th1/Th2型细胞因子动态变化

暴磊，刘素娜，李娟，王娟，张红义，侯建永，郝长付，姚武

《卫生研究》

2016

采用ChIP-chip技术分析大鼠肺成纤维细胞转分化前后全基因组蛋白H3K4三甲基化水平的改变

刘素娜，姚武，暴磊，李娟，张红义，侯建勇，王迪，陈慧婷，郝长付

《中国药理学与毒理学杂志》

2016

PM2.5污染与呼吸系统疾病门诊量关系的Meta分析

梁肖，闫英洁，张迪，刘文佳，平智广，姚武，吴卫东，燕贞

《环境与职业医学》

2016

大鼠矽肺噬菌体单链抗体库构建

张红义，郝长付，刘素娜，李娟，暴磊，侯建永，王迪，陈慧婷，姚武

《中国职业医学》

2016

[Dynamic changes of Th1/Th2 cytokines in lung tissue of experimental silicotic rat].

Lei Bao, Su'na Liu, Juan Li, Juan Wang, Hongyi Zhang, Jianyong Hou, Changfu Hao, Wu Yao

PubMed

2016

Application of created restriction site PCR-RFLP to identify POT1 gene polymorphism

Tuanwei Wang, Sihua Wang, Xiaoran Duan, Xiaolei Feng, Pengpeng Wang, Wu Yao, Yongjun Wu, Feifei Feng, Songcheng Yu, WU Yi-ming, Wei Wang

Biochemistry (Moscow)

DOI

2016

An improved polymerase chain reaction-restriction fragment length polymorphism assay for the detection of a PON2 gene polymorphism

Xiaoran Duan, Yongli Yang, Tuanwei Wang, Xiaolei Feng, Wu Yao, Zhen Yan, Wei Wang

Biomedical Reports

DOI

2016

Detection of the rs10250202 polymorphism in protection of telomeres 1 gene through introducing a new restriction enzyme site for PCR–RFLP assay

Sihua Wang, Xiaoran Duan, Tuanwei Wang, Xiaolei Feng, Pengpeng Wang, Wu Yao, Yongjun Wu, WU Yi-ming, Zhen Yan, Feifei Feng, Songcheng Yu, Wei Wang

SpringerPlus

DOI

2015

人单核细胞对煤焦沥青烟提取物诱导人永生化支气管上皮细胞c-Jun mRNA表达的影响

刘文佳，宋金燕，杨维超，晋乐飞，王威，姚武，吴卫东，吴逸明，燕贞

《环境与职业医学》

2015

河南省煤炭开采建设项目职业病危害评价现况调查

李磊，张陈熙，王思华，李国玉，牛心华，张育红，刘素香，姚武，王威

《职业与健康》

2015

煤工尘肺患者血清白介素18抗体与类风湿因子的表达

杨雯，姚武，郝长付，刘素娜，程远博，暴磊

《中华疾病控制杂志》

2015

Oxidative stress and endocytosis are involved in upregulation of interleukin-8 expression in airway cells exposed to PM2.5

Zhen Yan, Jia Wang, Juan Li, Nan Jiang, Ruiqin Q. Zhang, Weichao Yang, Wu Yao, Weidong Wu

Environmental Toxicology

DOI

2015

Silica promotes the transdifferentiation of rat circulating fibrocytes in vitro

Wu Yao, Suna Liu, Ju Li, Changfu Hao

Molecular Medicine Reports

DOI

2014

济源市某蓄电池厂职业卫生现状调查

李朋娟，姚武，周静，郝长付，陈淼

《河南医学研究》

2014

煤工尘肺患者血清中颗粒酶B抗体的表达及其意义

裴阳晴，刘素娜，暴磊，张红义，侯建永，郝长付，姚武

《河南医学研究》

2014

PM2.5对BEAS-2B细胞脂质过氧化损伤作用

李娟，杨维超，洪丽娟，姚武，吴卫东，吴逸明，燕贞

《中国公共卫生》

2014

煤工尘肺患者血清中血管内皮生长因子抗体的表达

程远博，刘素娜，暴磊，张红义，侯建永，郝长付，姚武

《四川大学学报(医学版)》

2014

煤焦沥青烟提取物对人支气管上皮细胞的脂质过氧化作用

洪丽娟，李娟，杨维超，刘文佳，姚武，燕贞

《环境与职业医学》

2014

0.5%溴鼠灵母药急性毒性、眼和皮肤刺激及皮肤致敏试验

李时恩，郭艳，周舫，姚武

《毒理学杂志》

2014

Transcriptional and posttranscriptional regulation and endocytosis were involved in zinc oxide nanoparticle-induced interleukin-8 overexpression in human bronchial epithelial cells

Zhen Yan, Lei Xu, Jie Han, Yongjun Wu, Wei Wang, Wu Yao, Weidong Wu

Cell Biology and Toxicology

DOI

2013

POT1 RNA干扰与煤焦沥青烟提取物对BEAS-2B细胞端粒的损伤效应

张建功，王思华，李小龙，姚武，燕贞，吴拥军，吴逸明，王威

《中华疾病控制杂志》

2013

煤焦沥青烟提取物对THP-1细胞炎性因子表达影响

宋金燕，冯斐斐，李娟，王威，姚武，吴卫东，吴逸明，燕贞

《中国公共卫生》

2013

许昌某烟草厂职业卫生现状调查

张丽，周静，姚武，郝长付，韩瑜，王丽霞

《河南医学研究》

2013

中国国家职业卫生标准发展动态分析

张育红，段晓冉，王团伟，姚武，王威

《河南医学研究》

2013

Role of insulin-like growth factor II receptor in transdifferentiation of free silica-induced primary rat lung fibroblasts.

Chang Fu Hao, Xiao Fang Li, Wu Yao

PubMed

DOI

2013

[Coal tar pitch smoke extract-induced pyroptosis in human bronchial epithelial cells].

Jinyan Song, Ya-nan Feng, Li-peng Du, Wu Yao, WU Yi-ming, Weidong Wu, Zhen Yan

PubMed

2012

干扰素对二氧化硅致肺成纤维细胞激活的抑制效应

郝长付，张光辉，姚武，赵阳

《现代预防医学》

2012

肺癌组织热休克蛋白70提取物对A549细胞增殖的影响

孙鹏辉，梁守沛，陆皓泉，李杰，王小龙，许东，姚武，吴逸明，周舫

《郑州大学学报(医学版)》

2012

表观遗传学及其应用研究进展

尤媛媛，郝长付，姚武

《现代预防医学》

2012

煤工尘肺患者循环DNA的提取鉴定及应用

尤媛媛，杨雯，姚武，郝长付

《河南医学研究》

2012

Estimation of a Safe Level for Occupational Exposure to Vinyl Chloride Using a Benchmark Dose Method in Central China

Jie Jiao, Nannan Feng, Yong Li, Yuan Sun, Wu Yao, Wei Wang, Guanghui Zhang, Shi‐yi Sun, Hongshan Tan, Qi Wang, Yiliang Zhu, Yongliang Li, Paul W. Brandt‐Rauf, Zhao‐lin Xia

Journal of Occupational Health

DOI

2012

[Effects of heat shock protein 70-2 gene polymorphisms on the transcription of HSP 70-2 mRNA and the translation of HSP 70 protein in lung cancer].

Hao-quan Lu, Yuzhen Wang, Peng-hui Sun, Shoupei Liang, Jie Li, Xiaolong Wang, Dong Xu, Wu Yao, WU Yi-ming, Fang Zhou

PubMed

2012

[DNA methylation levels of genome in cFb transdifferentiation induced by SiO2 in rats].

Yongxing Wang, Wu Yao, Bin Gao, Yongcheng Yao, WU Yi-ming, Changfu Hao

PubMed

2012

HER3-Ab serum level in dust exposed workers

Wu Yao

Henan yixue yanjiu

2011

预防医学职业卫生与职业医学课教学实践的探讨

郝长付，王威，姚武

《河南医学研究》

2011

肺鳞癌组织中热休克蛋白27表达及意义

燕贞，冯艳铭，周舫，李时恩，姚武，吴卫东，吴逸明

《中国公共卫生》

2011

焦炉逸散物对作业工人的健康危害

刘海东，王娜，李时恩，王丽霞，祝寒松，姚武，吴逸明

《现代预防医学》

2011

创造酶切位点PCR-RFLP检测MTHFR(rs2274976)基因多态性

王威，杨永利，周舫，画宝勇，郝长付，姚武，吴逸明，吴拥军

《卫生研究》

2011

尘肺病噬菌体单链抗体库的构建及鉴定

翟伟，郝长付，高彬，姚武

《郑州大学学报(医学版)》

2011

尘肺患者血清肿瘤坏死因子-α表达水平的Meta分析

高彬，郝长付，王永星，姚武

《卫生研究》

2011

肺癌组织中HSP70-1+190(G/C)多态性对HSP70-1 mRNA及HSP70蛋白表达的影响

周舫，梁守沛，王玉珍，王明君，许东，姚武，吴逸明

《郑州大学学报(医学版)》

2011

[A meta-analysis of susceptibility to pneumoconiosis and polymorphism of tumor necrosis factor-α 308 and 238 locus].

Li Ju, Changfu Hao, Wu Yao, Yun Yu-xia, Bin Gao, Yongxing Wang

PubMed

2011

Construction and identification of human phage single-chain antibody library for pneumoconiosis

Wu Yao

Journal of Zhengzhou University

2011

Extraction and application of circulating DNA in coal workers preumoconiosis(CWP) patients

Wu Yao

Journal of Medical Forum

2011

Inhibitory effect of colchicine on silica dioxide-induced rat lung fibroblast activation

Wu Yao

Journal of Zhengzhou University

2010

RGD短肽对二氧化硅致肺成纤维细胞激活的抑制效应

张光辉，姚武，郝长付，邵苗苗，高彬

《现代预防医学》

2010

HSP70基因多态性对煤工尘肺遗传易感性的影响

周舫，秦卫东，王玉珍，李伟辉，梁守沛，姚武，吴逸明

《卫生研究》

2010

Ras相关核蛋白在肺鳞癌组织中的表达及意义

燕贞，李智涛，姚武，吴卫东，吴逸明

《卫生研究》

2010

基于问题学习在职业卫生与职业医学教学中的应用

王威，郝长付，姚武，吴逸明，李文杰

《河南医学研究》

2009

硫酸锌对人呼吸道上皮细胞转录因子AP-1与NF-κB的活化作用

燕贞，张巧，徐磊，吴卫东，李时恩，姚武，吴逸明

《毒理学杂志》

2009

实验性矽肺相关基因的表达谱研究

姚武，张欢，郝长富，张光辉，秦卫东

《现代预防医学》

2009

煤工尘肺与吸烟关系调查

李宏斌，姚武

《现代疾病预防控制》

2008

接尘工人血清中TGF-β1表达水平的研究

陈琴，周舫，李伟辉，赵勇，周铁峰，李慧芳，秦卫东，徐志勇，姚武

《中华全科医学》

2008

亲环素在非小细胞肺癌中的高表达及其与临床病理特征的关系

冯艳铭，吴卫东，燕贞，姚武，吴逸明

《海军军医大学学报》

2008

慢病毒介导的CyPA基因沉默对非小细胞肺癌细胞生长的影响

冯艳铭，王琳，姚武，吴卫东，吴逸明

《山东医药》

2008

氧化锌对人呼吸道上皮细胞IL-8表达作用

吴卫东，张巧，姚武，吴逸明

《中国公共卫生》

2008

表皮生长因子受体及PI3K在硫酸锌诱导人呼吸道上皮细胞间粘附分子-1表达过程中的作用

张巧，吴卫东，张同存，时松和，徐玉宝，姚武，吴逸明

《卫生研究》

2008

PDGF-AA和PDGF-BB在大鼠矽肺组织中的表达及意义

周冬，焦洁，许东，徐志勇，秦卫东，姚武

《医药论坛杂志》

2008

Zn2+对人Ⅱ型肺泡上皮A549细胞IL-8和TNF-α mRNA和蛋白表达水平的影响

张巧，杨海军，吴卫东，时松和，徐玉宝，姚武，吴逸明

《卫生研究》

2008

CTGF和TGF-β1在实验性矽肺肺组织中的表达及其意义

徐志勇，焦洁，姚武，周舫，秦卫东，张欢

《现代预防医学》

2008

结缔组织生长因子、Ⅲ型前胶原氨基末端肽在接尘工人血清中表达水平的变化及意义

陈琴，周舫，赵勇，李伟辉，周铁峰，李慧芳，秦卫东，徐志勇，姚武

《中国煤炭工业医学杂志》

2008

[Effect of coking oven emissions on level of serum oxidation-reduction and peripheral white blood cellular ras P21 and P53 in coke oven workers].

Qiao Zhang, Fang Zhou, Wu Yao, Yi-bo Zhao, Zhi-yuan Li, Yu-bao Xu, WU Yi-ming

PubMed

2007

尘肺病患者血清PDGF和PⅢNP含量的测定

周舫，姚武，李时恩，王娜，冯斐斐，秦卫东，李伟辉，徐智勇，吴逸明

《中国工业医学杂志》

2007

2005年河南省放射卫生监督的抽查调查

画宝勇，姚武，吴维超

《现代预防医学》

2006

GSTM1、GSTT1基因缺失与肺癌易感性的关系

姚武，王娜，吴拥军，吴逸明

《中国公共卫生》

2006

转化生长因子β1血清浓度及基因多态性与煤工尘肺的关系

姚武，郝长付，吴逸明，王娜，孙长青，李丽

《中国职业医学》

2006

煤工尘肺患者一氧化氮、丙二醛、超氧化物歧化酶的测定分析

王娜，姚武，付鹏钰，牛姬飞，焦洁

《中国职业医学》

2006

煤工尘肺患者TGF-β1基因与环境暴露因素的交互作用

毋小玉，姚武，李丽，郝长付，王娜

《郑州大学学报(医学版)》

2006

煤工尘肺患者血清转化生长因子β1、成纤维细胞生长因子含量检测

姚武，王娜，庄东刚，焦洁，付鹏钰

《郑州大学学报(医学版)》

2006

转化生长因子β1基因多态性对煤工尘肺遗传易感性的影响

姚武，郝长付，王娜，赵毅波

《现代预防医学》

2006

TGF-β1在实验性矽肺大鼠肺组织中的表达及其意义

郝长付，姚武，吴逸明

《医药论坛杂志》

2006

TGF-β1、PDGF、CTGF在尘肺病患者血清中的表达水平变化及意义

姚武，冯斐斐，焦洁，王娜

《四川大学学报(医学版)》

2006

[Expression level and significance of TGF-beta1, PDGF, CTGF in serum of patients with pneumoconiosis].

Wu Yao, Feifei Feng, Jie Jiao, Na Wang

PubMed

2005

尘肺病相关基因筛选研究

姚武

《四川大学》

2005

煤工尘肺患者血清转化生长因子β1水平与其基因多态性的关系研究

姚武，王治明，王绵珍，郝长付，王娜

《四川大学学报(医学版)》

2005

90%甲胺基阿维菌素苯甲酸盐原药的急性毒性研究

赵毅波，陈小玉，姚武

《现代疾病预防控制》

2005

煤工尘肺患者血清细胞因子及氧化损伤水平研究

姚武，王治明，王绵珍，王娜

《四川大学学报(医学版)》

2005

冷库工人血浆中HSP70抗体及脂质过氧化水平的研究

周舫，张巧，姚武，谷庆，张仁忠，徐海，何美安，邬堂春，吴逸明

《中国工业医学杂志》

1999

六价铬男性生殖毒性的初步探讨

李洪，陈琼宇，李时恩，徐玉宝，姚武，陈琛，Erik Erist

《中华预防医学杂志》

1998

六价铬对接触工人子代智力发育影响的研究

陈琼宇，李洪，李时恩，徐玉宝，姚武，陈琛

《中国公共卫生学报》

1997

锰作业男工生殖毒研究

何全安，杨进伟，赵雅斐，周道明，姚武，陈琛，吴卫平

《现代疾病预防控制》

1993

男性汞接触者血汞和精浆汞水平

许东，姚武，刘玮，肖文

《毒理学杂志》

1991

氯乙烯对机体损伤效应的观察

孟爱民，陈琛，杨廷章，姚武，李志远，郜民生，贾允山

《现代疾病预防控制》

1990

苯作业者外周血淋巴细胞的染色体畸变、SCE和微核率的实验观察

陈琛，姚武，许东，李灵宏，马玉英，周道明，李娥姣

《现代疾病预防控制》

1990

职业性铅接触者生物学效应分析

许东，陈琛，杨廷璋，李志远，姚武，赵一波，李灵宏，马玉英，徐玉宝

《中国职业医学》

1989

郑州地区人乳铅、汞含量测定

陈琛，白燕，姚武，陈小玉，陈琼宇

《中国公共卫生》

精选作品

期刊论文

C3a-C3ar1 axis mediates macrophage M1 polarization to drive silicosis inflammation and fibrosis

Temporal modulation of cuproptosis and autophagy mediates nanographene-driven pulmonary fibrosis progression

小鼠硅沉着病发生发展过程中肺部菌群的变化

基于16S rDNA测序的硅沉着病小鼠肺部和肠道菌群特征分析

外泌体在听力损失治疗中的研究进展

Unveiling Novel Biomarkers: Ferroptosis and m1A in the Progression of Nanographene‐Induced Lung Fibrosis

KLF4/FOXF1 axis alleviates silicosis fibrosis by modulating fibroblast behavior and extracellular matrix remodeling

Dysregulation of immune checkpoint LAG3 in mice exposed to silica

Fra2, a potential therapeutic target for silicosis

Innate immune checkpoint SIRPα/CD47 blockade ameliorates silica-induced pulmonary fibrosis by modulating macrophage immunity

两种职业健康风险模型在铸造作业中矽尘的评估和应用

噪声和电焊烟尘联合作用与职业性噪声性听力损失关系

苯系物与噪声联合暴露对男工职业性噪声性听力损失的影响

男性噪声作业工人血糖水平与职业性噪声性听力损失的关系研究

PD-L1 upregulation in activated fibroblasts promotes silica particle-induced pulmonary fibrosis

Effect and Mechanism of Action of BMSC-derived Exosomes on Gas Explosion-induced Blast Lung Injury.

The role of the PI3K/AKT/mTOR pathway in mediating PD-L1 upregulation during fibroblast transdifferentiation

Jun and JunB members of the AP-1 complex are potential therapeutic targets for silicosis

FAP expression dynamics and role in silicosis: Insights from epidemiological and experimental models

FOXF1 reverses lung fibroblasts transdifferentiation via inhibiting TGF-β/SMAD2/3 pathway in silica-induced pulmonary fibrosis

Bioinformatics-based dynamics of cuproptosis -related indicators in experimental silicosis

Exposure to micron-grade silica particles triggers pulmonary fibrosis through cell-to-cell delivery of exosomal miR-107

Manganese accumulation in red blood cells as a biomarker of manganese exposure and neurotoxicity

Time-series transcriptome analysis mapping pulmonary immune checkpoint atlas of experimental silicosis

Corrigendum to “A2aR inhibits fibrosis and the EMT process in silicosis by regulating Wnt/β-catenin pathway” [Ecotoxicol. Environ. Saf. 249 (2023) 114410]

Expression levels of key immune indicators and immune checkpoints in manganese-exposed rats

两种评估模型在某碳纤维厂职业健康风险评估中的应用

Changes in serum TIM-3 and complement C3 expression in workers due to Mn exposure

The role of N6-methyladenosine methylation in PAHs-induced cancers

Silica-exposed macrophages-secreted exosomal miR125a-5p induces Th1/Th2 and Treg/Th17 cell imbalance and promotes fibroblast transdifferentiation

GGA (geranylgeranylacetone) ameliorates bleomycin-induced lung inflammation and pulmonary fibrosis by inhibiting apoptosis and oxidative stress

Benchmark Dose Assessment for Coke Oven Emissions-Induced Mitochondrial DNA Copy Number Damage Effects.

Geranylgeranylacetone, an inducer of heat shock protein 70, attenuates pulmonary fibrosis via inhibiting NF-κB/NOX4/ROS signalling pathway in vitro and in vivo

Mitochondrial folate pathway regulates myofibroblast differentiation and silica-induced pulmonary fibrosis

PD-1/PD-L1 axis in organ fibrosis

Chain-mediating effect of interaction between telomeres and mitochondria under oxidative stress in coke oven workers

Benchmark dose estimation based on oxidative damage in Chinese workers exposed to benzene series compounds

EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS

Proteomic Analysis Revealed the Involvement of Autophagy in Rat Acute Lung Injuries Caused by Gas Explosion Based on a Data-Independent Acquisition Strategy.

HMGB1 coordinates with Brahma-related gene 1 to promote epithelial-mesenchymal transition via the PI3K/Akt/mTOR pathway in BEAS-2B cells

Effect and interaction of TNKS genetic polymorphisms and environmental factors on telomere damage in COEs-exposure workers

The diagnostic value of circulating abnormal cells in early lung cancer.

NOX2抑制剂gp91 ds-tat缓解瓦斯爆炸引起的大鼠肺损伤

A2aR inhibits fibrosis and the EMT process in silicosis by regulating Wnt/β-catenin pathway

MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells

Exosomal miR-125a-5p regulates T lymphocyte subsets to promote silica-induced pulmonary fibrosis by targeting TRAF6

Expression level and function analysis of serum miRNAs in workers with occupational exposure to benzene series

Detection and analysis of lung microbiota in mice with lung cancer lacking the NLRP3 gene

Lysophosphatidylcholine acyltransferase 1 alleviates silica-induced pulmonary fibrosis by modulating lipid metabolism

Glycyrrhizic Acid Attenuates Pulmonary Fibrosis of Silicosis by Inhibiting the Interaction between HMGB1 and BRG1 through PI3K/Akt/mTOR Pathway

Occupational Low-Dose Radiation Affects the Expression of Immune Checkpoint of Medical Radiologists

Inhibition of HIF-1α Attenuates Silica-Induced Pulmonary Fibrosis

Dendritic cells activated by cimetidine induce Th1/Th17 polarization in vitro and in vivo

Prediction of lung cancer using gene expression and deep learning with KL divergence gene selection

LncRNA UCA1 regulates silicosis-related lung epithelial cell-to-mesenchymal transition through competitive adsorption of miR-204-5p

Mechanism of LncRNA XIST/ miR-101–3p/ZEB1 axis in EMT associated with silicosis

PD-1/PD-L1 inhibitor ameliorates silica-induced pulmonary fibrosis by maintaining systemic immune homeostasis

Epigenetic Changes and Functions in Pneumoconiosis

A549细胞上皮-间质转分化中差异表达基因的生物信息学分析

矽肺大鼠肺组织差异蛋白筛选与质谱分析

NF-κB/NOX1信号通路在TNF-α诱导A549细胞凋亡中的作用

尘肺病患者血清差异表达miRNAs筛选与生物信息学分析

热休克蛋白70对人肺腺癌A549细胞上皮间质转化的影响

miR-107在TGF-β诱导的NIH-3T3细胞转分化中的作用

Influence of Silica Exposure for Lung Silicosis Rat

Research progress on the mechanism of ferroptosis and its clinical application

PPARγ/LXRα axis mediated phenotypic plasticity of lung fibroblasts in silica-induced experimental silicosis

Relationship between TERT Polymorphism and Telomere Length in Workers Exposed to Omethoate.

Genetic variants in telomerase-associated protein 1 are associated with telomere damage in PAH-exposed workers

Mesenchymal stem cells ameliorate silica‐induced pulmonary fibrosis by inhibition of inflammation and epithelial‐mesenchymal transition

In vitro co-culture model of human monocyte-derived dendritic cells and T cells to evaluate the sensitization of dinitrochlorobenzene

SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation

Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats

Genetic polymorphisms of metabolic enzyme genes associated with leukocyte mitochondrial DNA copy number in PAHs exposure workers

TGF-β promote epithelial-mesenchymal transition via NF‐κB/NOX4/ROS signal pathway in lung cancer cells

Overexpression of heat shock protein 70 inhibits epithelial-mesenchymal transition and cell migration induced by transforming growth factor-β in A549 cells

Estimations of benchmark dose for urinary metabolites of coke oven emissions among workers

转化生长因子-β1致肺成纤维细胞转分化过程中差异表达基因的筛选和验证