王洛洋｜青岛大学｜学者主页

2026

Unlocking the potential: current landscape and future directions of immunotherapy in gastric cancer

Yingfei Zhou, Luling Wei, Luoyang Wang, Bei Zhang, Jie Liang

Frontiers in Immunology

2026

Interleukin-35 and pancreatic cancer: research progress from tumor-promoting mechanisms to treatment resistance

Yuanzhen Guo, Jie Liang, Xiaoli Liu, Luoyang Wang, Wei Li, Meiying Song, Xiao Wang, Yi Liu, Zhen Li, Shuai Li, Ningjing Fu, Bei Zhang

Cytokine

DOI

2026

Boosting T cell antioxidant capacity: A strategic approach to overcome immunosuppression in solid tumors

Liu Fan, Yuxin Pang, Luoyang Wang, Dimkpa Christabel Kechiyerunda, Bei Zhang, Jie Liang

Redox Biology

DOI

2026

Immune cells in liver transplantation: Dual roles, mechanistic insights, and targeted therapeutic strategies

Yuanzhen Guo, Luoyang Wang, Wei Li, Xiaoli Liu, Jie Liang, Meiying Song, Xiao Wang, Yi Liu, Zhen Li, Shuai Li, Ningjing Fu, Jingzhen Cai, Bei Zhang

Immunologic Research

DOI

2026

Targeting HIF as a Promising Approach to Synergize With Immune Checkpoint Inhibitors

Shuai Li, Liu Y, Xiaoli Liu, Xiao Wang, Wenhua Li, Meiying Song, Ningjing Fu, Yuanzhen Guo, Zhen Li, Q Y Zhang, Jie Liang, Luoyang Wang, Bei Zhang

International Journal of Cancer

DOI

2026

SOX18 at the crossroads of cancer: integrating signaling pathways to drive malignant transformation and immune evasion

Xiaoli Liu, Jie L. Liang, Xiao Wang, Wei Tzu Li, Yi Liu, Luoyang Wang, Mengting Zhou, Guixian Liu, Meiying Song, Li Zhang, Yanyan Yang, Bei Zhang

Functional & Integrative Genomics

DOI

2026

Lactate drive M2 polarization via OXPHOS and Cebpb and accelerate peripheral nerve regeneration

Wei Li, Xiao Wang, Xiaoli Liu, Luoyang Wang, Jie Liang, Yu Cui, Yi Liu, Mengting Zhou, Zijie Yang, Meiying Song, Yanyan Yang, Li Zhang, Bei Zhang

International Immunopharmacology

DOI

2026

The CXCL12 – CXCR4 / CXCR7 axis as a therapeutic target in liver cancer: Enhancing immune evasion and the future of combination therapies

Meiying Song, Xueteng Wang, Jie Liang, Luoyang Wang, Jinzhen Cai, Bei Zhang

International Journal of Cancer

DOI

2026

Cyclic adenosine monophosphate signaling pathway in tumor-associated macrophages: molecular mechanisms and tumor immunotherapy

Liu Y, Shuai Li, Wenhua Li, Mengting Zhou, Jie Liang, Liu X, X Y Wang, Yuanzhen Guo, Zhen Li, Bei Zhang, Luoyang Wang

Carcinogenesis

DOI

2025

ARA290, an alternative of erythropoietin, inhibits activation of NLRP3 inflammasome in schwann cells after sciatic nerve injury

Guixian Liu, Wei Li, Suli Jiang, Jie Liang, Meiying Song, Luoyang Wang, Xiao Wang, Xiaoli Liu, Zijie Yang, Li Zhang, Li Zhang, Yanyan Yang, Bei Zhang

European Journal of Pharmacology

DOI

2025

CCL5: An emerging key target and progress in the targeted therapy of hepatocellular carcinoma

Xiaoli Liu, Jie Liang, Li‐Zhen Zhao, Wei Li, Luoyang Wang, Xiao Wang, Yi Liu, Mengting Zhou, Xinqiang Li, Zhuoyu Jia, Meiying Song, Li Zhang, Li Zhang, Yanyan Yang, Jinzhen Cai, Bei Zhang

Molecular Immunology

DOI

2025

The Dance Between Schwann Cells and Macrophages During the Repair of Peripheral Nerve Injury

Wei Li, Guixian Liu, Jie Liang, Xiao Wang, Meiying Song, Xiaoli Liu, Luoyang Wang, Zijie Yang, Bei Zhang

Neuroscience Bulletin

DOI

2025

INSL3 promotes macrophage polarization to an immunosuppressive phenotype via the cAMP downstream signaling pathway and Akt/mTOR pathway

Mengting Zhou, Yi Liu, Cuiping Li, Xizhong Yang, Cuijie Ji, Wěi Li, Meiying Song, Zijie Yang, Guixian Liu, Xinping Liang, Jie Liang, Bei Zhang, Luoyang Wang

International Immunopharmacology

DOI

2024

PKM2, the “K+ sink” in the tumor interstitial fluid

Wenjing Na, Wenfeng Zeng, Kai Song, Youwang Wang, Luoyang Wang, Ziran Zhao, Lingtao Jin, Ping Zhu, Wei Ping Liang

Protein & Cell

DOI

2024

Pathogenic Th17 cell-mediated liver fibrosis contributes to resistance to PD-L1 antibody immunotherapy in hepatocellular carcinoma

Meiying Song, Luoyang Wang, Suli Jiang, Jie Liang, Wěi Li, Wei Rao, Qiaochu Du, Guixian Liu, Haining Meng, Lei Tang, Zhifei Li, Yanyan Yang, Li Zhang, Bei Zhang, Bei Zhang

International Immunopharmacology

DOI

2024

FOXM1 mediates methotrexate resistance in osteosarcoma cells by promoting autophagy

Luoyang Wang, Dongchang Zhai, Lei Tang, Hui Zhang, Xinlong Wang, Ning Ma, Xiaoyue Zhang, Mingguo Cheng, Ruowu Shen

Acta Biochimica et Biophysica Sinica

DOI

2024

CXCL1-CXCR2 axis mediates inflammatory response after sciatic nerve injury by regulating macrophage infiltration

Suli Jiang, Wei Li, Meiying Song, Jie Liang, Guixian Liu, Qiaochu Du, Luoyang Wang, Haining Meng, Lei Tang, Yanyan Yang, Bei Zhang

Molecular Immunology

DOI

2024

Inhibition of inosine metabolism of the gut microbiota decreases testosterone secretion in the testis

Lei Tang, Xizhong Yang, Mengting Zhou, Lingxin Feng, Cuijie Ji, Jie Liang, Bei Zhang, Ruowu Shen, Luoyang Wang

mSystems

DOI

2023

Enhancing therapeutic effects of murine cancer vaccine by reshaping gut microbiota with Lactobacillus rhamnosus GG and jujube powder

Nan Jing, Luoyang Wang, Huiren Zhuang, Guoqiang Jiang, Zheng Liu

Frontiers in Immunology

DOI

2023

IL-17A functions and the therapeutic use of IL-17A and IL-17RA targeted antibodies for cancer treatment

Meiying Song, Jie Liang, Luoyang Wang, Wei Li, Suli Jiang, Shuo Xu, Lei Tang, Qiaochu Du, Guixian Liu, Haining Meng, Dongchang Zhai, Shangheng Shi, Yanyan Yang, Li Zhang, Bei Zhang

International Immunopharmacology

DOI

2023

The CXCL12-CXCR4-NLRP3 axis promotes Schwann cell pyroptosis and sciatic nerve demyelination in rats

Wei Li, Jie Liang, Shaohua Li, Suli Jiang, Meiying Song, Shuo Xu, Luoyang Wang, Haining Meng, Dongchang Zhai, Lei Tang, Yanyan Yang, Bei Zhang

Clinical & Experimental Immunology

DOI

2023

The role of CXCL1/CXCR2 axis in neurological diseases

Suli Jiang, Jie Liang, Wei Li, Luoyang Wang, Meiying Song, Shuo Xu, Guixian Liu, Qiaochu Du, Dongchang Zhai, Lei Tang, Yanyan Yang, Li Zhang, Li Zhang, Bei Zhang

International Immunopharmacology

DOI

2023

PKC-ζ mediated reduction of the extracellular vesicles-associated TGF-β1 overcomes radiotherapy resistance in breast cancer

Fayun Zhang, Zifeng Zheng, Luoyang Wang, Wenfeng Zeng, Wenjing Wei, Chunling Zhang, Ziran Zhao, Wei Ping Liang

Breast Cancer Research

DOI

2023

The role of the sex hormone-gut microbiome axis in tumor immunotherapy

Luoyang Wang, Lei Tang, Dongchang Zhai, Meiying Song, Wei Li, Shuo Xu, Suli Jiang, Haining Meng, Jie Liang, Yingying Wang, Bei Zhang

Gut Microbes

DOI

2022

Promoting intestinal IgA production in mice by oral administration with anthocyanins

Xuerun Liu, Luoyang Wang, Huiren Zhuang, Zhenghuan Yang, Guoqiang Jiang, Zheng Liu

Frontiers in Immunology

DOI

2022

Sex-Biased Immune Responses to Antibiotics during Anti-PD-L1 Treatment in Mice with Colon Cancer

Nan Jing, Luoyang Wang, Huiren Zhuang, Chao Ai, Guoqiang Jiang, Zheng Liu

Journal of Immunology Research

DOI

2022

Research progress of targeting NLRP3 inflammasome in peripheral nerve injury and pain

Wei Li, Jie Liang, Shaohua Li, Luoyang Wang, Shuo Xu, Suli Jiang, Meiying Song, Haining Meng, Dongchang Zhai, Lei Tang, Yanyan Yang, Li Zhang, Bei Zhang

International Immunopharmacology

DOI

2021

Ultrafine Jujube Powder Enhances the Infiltration of Immune Cells during Anti-PD-L1 Treatment against Murine Colon Adenocarcinoma

Nan Jing, Luoyang Wang, Huiren Zhuang, Guoqiang Jiang, Zheng Liu

Cancers

DOI

2021

Jujube Powder Enhances Cyclophosphamide Efficiency against Murine Colon Cancer by Enriching CD8+ T Cells While Inhibiting Eosinophilia

Huiren Zhuang, Nan Jing, Luoyang Wang, Guoqiang Jiang, Zheng Liu

Nutrients

DOI

2018

柚皮素:新一代免疫调节剂

曾文峰，张发云，杜刚军，金凌涛，秦蕾，董文娟，张超，王洛洋，尹晓哲，张春玲，梁伟

《生物化学与生物物理进展》

王洛洋

精选作品

期刊论文

Unlocking the potential: current landscape and future directions of immunotherapy in gastric cancer

Interleukin-35 and pancreatic cancer: research progress from tumor-promoting mechanisms to treatment resistance

Boosting T cell antioxidant capacity: A strategic approach to overcome immunosuppression in solid tumors

Immune cells in liver transplantation: Dual roles, mechanistic insights, and targeted therapeutic strategies

Targeting HIF as a Promising Approach to Synergize With Immune Checkpoint Inhibitors

SOX18 at the crossroads of cancer: integrating signaling pathways to drive malignant transformation and immune evasion

Lactate drive M2 polarization via OXPHOS and Cebpb and accelerate peripheral nerve regeneration

The CXCL12 – CXCR4 / CXCR7 axis as a therapeutic target in liver cancer: Enhancing immune evasion and the future of combination therapies

Cyclic adenosine monophosphate signaling pathway in tumor-associated macrophages: molecular mechanisms and tumor immunotherapy

ARA290, an alternative of erythropoietin, inhibits activation of NLRP3 inflammasome in schwann cells after sciatic nerve injury

CCL5: An emerging key target and progress in the targeted therapy of hepatocellular carcinoma

The Dance Between Schwann Cells and Macrophages During the Repair of Peripheral Nerve Injury

INSL3 promotes macrophage polarization to an immunosuppressive phenotype via the cAMP downstream signaling pathway and Akt/mTOR pathway

PKM2, the “K+ sink” in the tumor interstitial fluid

Pathogenic Th17 cell-mediated liver fibrosis contributes to resistance to PD-L1 antibody immunotherapy in hepatocellular carcinoma

FOXM1 mediates methotrexate resistance in osteosarcoma cells by promoting autophagy

CXCL1-CXCR2 axis mediates inflammatory response after sciatic nerve injury by regulating macrophage infiltration

Inhibition of inosine metabolism of the gut microbiota decreases testosterone secretion in the testis

Enhancing therapeutic effects of murine cancer vaccine by reshaping gut microbiota with Lactobacillus rhamnosus GG and jujube powder

IL-17A functions and the therapeutic use of IL-17A and IL-17RA targeted antibodies for cancer treatment

The CXCL12-CXCR4-NLRP3 axis promotes Schwann cell pyroptosis and sciatic nerve demyelination in rats

The role of CXCL1/CXCR2 axis in neurological diseases

PKC-ζ mediated reduction of the extracellular vesicles-associated TGF-β1 overcomes radiotherapy resistance in breast cancer

The role of the sex hormone-gut microbiome axis in tumor immunotherapy

Promoting intestinal IgA production in mice by oral administration with anthocyanins

Sex-Biased Immune Responses to Antibiotics during Anti-PD-L1 Treatment in Mice with Colon Cancer

Research progress of targeting NLRP3 inflammasome in peripheral nerve injury and pain

Ultrafine Jujube Powder Enhances the Infiltration of Immune Cells during Anti-PD-L1 Treatment against Murine Colon Adenocarcinoma

Jujube Powder Enhances Cyclophosphamide Efficiency against Murine Colon Cancer by Enriching CD8+ T Cells While Inhibiting Eosinophilia

柚皮素:新一代免疫调节剂

预印本

Research progress of insulin-like peptide 3 in bone metabolism

研究方向