蔡挺｜中国药科大学｜学者主页

百晓学者学者目录

精选作品

期刊论文

2026

以共聚维酮和交联聚维酮为载体的尼莫地平固体分散体物理稳定性和溶出行为研究

任沁，刘怡，纪晓虹，郭敏珊，蔡挺

《中国现代应用药学》

DOI

2026

Surfactant Regulation of the Solution-Mediated Phase Transformation of Nitrofurantoin Anhydrate to Monohydrate

Zhuang-Zhuang Chen, Xi-Yan Wang, An Chen, Lin Li, Zhong-Ting Zhuang, Min-Shan Guo, Ting Cai

Pharmaceutical Research

DOI

2026

Accelerating pharmaceutical cocrystal discovery via in silico screening: Prediction of formation and properties.

Qi Zeng, Yuting Peng, Li-Xuan Zhang, Min-Shan Guo, Ting Cai

Drug Discovery Today

DOI

2026

Stabilizing liquid-like drug-rich intermediates by bile salts to suppress phase transformation and promote rapid absorption of cocrystals.

Xiao-Hong Ji, Zhong-Ting Zhuang, Haotian Liu, Qinyuan Chen, Yang Yu, Yi-Chen Bao, Min-Shan Guo, Ting Cai

Journal of Controlled Release

DOI

2026

Effect of Alkyl Chain Length on Physicochemical and Pharmacokinetic Performance of Aripiprazole Fatty Acid Prodrugs for Long-Acting Injectable Suspensions

An Chen, Cong Lai, Hao Zhai, Shi-Yang Zhang, Yi-Jing Zhang, Ting Cai

Pharmaceutics

DOI

2026

A cocrystal-based long-acting injectable suspension platform enables tunable drug release.

An Chen, Cong Lai, Wei-Jie Xu, Zi-Lin He, Hao Zhai, Xian Rui, Min-Shan Guo, Ting Cai

Journal of Controlled Release

DOI

2026

Continuous control of thermal responses in dynamic crystals via solid solution engineering

Jiantao Meng, Yahui Su, Hang Zhu, Wenrui Chen, An Chen, Yuan Su, Ting Cai

CrystEngComm

DOI

2025

添加剂调控药物晶体形貌研究进展

任怡霏，苏媛，蔡挺

《中国药科大学学报》

2025

Crystal engineering for poorly water-soluble drugs: From design to applications

An Chen, Ya-Yun Peng, Zhuang-Zhuang Chen, Yi Lu, Min-Shan Guo, Ting Cai

Acta Pharmaceutica Sinica B

DOI

2025

Dynamic Molecular Cocrystals with Alkyl Chain Dependent Thermosalient Phase Transitions

Jiantao Meng, Yuan Su, Hang Zhu, Jie Zhang, Ting Cai

Advancement of science

DOI

2025

Dispensing Small Scale Solids Using Chemical-Coated Beads for Solid Form Screening.

Jiantao Meng, Chen-Gang Zhou, Lei Yin, Jian Chen, Junwei Xi, Chen Chen, Ting Cai, Y. Gui

Molecular Pharmaceutics

DOI

2025

Molar Ratio-Dependent Crystallization in Coamorphous Celecoxib-Carbamazepine Systems: The Interplay of Thermodynamics and Kinetics.

Min-Qian Luo, An Chen, Shiyu Shan, Min-Shan Guo, Ting Cai

Molecular Pharmaceutics

DOI

2025

Interpretable machine learning for solvent prediction and mechanistic insights in multi-component crystal screening

Qi Zeng, Yiqun Zhang, Yu-Ting Peng, Qun Zeng, Guangxu Sun, Min-Shan Guo, Ting Cai

Chemical Engineering Journal

DOI

2024

以交联聚维酮为载体的吲哚美辛固体分散体稳定性和溶出行为研究

任沁，刘怡，王伟芳，蔡挺

《中国药学杂志》

2024

难溶性药物共晶的溶出与吸收研究进展

张少钲，单识宇，郭敏珊，蔡挺

《药学学报》

2024

载药量和成膜材料HPMC相对分子质量对盐酸氟桂利嗪纳米晶口溶膜关键质量属性的影响

刘国敏，翟豪，蔡挺

《中国医药工业杂志》

2024

Shape memory and self-healing in a molecular crystal with inverse temperature symmetry breaking

Jiantao Meng, Yuan Su, Hang Zhu, Ting Cai

Chemical Science

DOI

2024

The role of alkyl chain length in the melt and solution crystallization of paliperidone aliphatic prodrugs

An Chen, Peishan Cai, Ya-Yun Peng, Min-Shan Guo, Yuan Su, Ting Cai

IUCrJ

DOI

2024

Accelerated stability modeling of recrystallization from amorphous solid Dispersions: A Griseofulvin/HPMC-AS case study.

Ariana Sheng-Chu Leon, Kenneth C. Waterman, Guanhua Wang, Likun Wang, Ting Cai, Xiaohua Zhang

International journal of pharmaceutics

DOI

2024

Solution-mediated phase transformation of cocrystals at the solid-liquid interface: Relationships between the supersaturation generation rate and transformation pathway.

Runhui Fan, An Chen, Yang Yu, Ting Cai, Min-Shan Guo

International journal of pharmaceutics

DOI

2024

Effects of Polymers on Cocrystal Growth in a Drug-Drug Coamorphous System: Relations between Glass-to-Crystal Growth and Surface-Enhanced Crystal Growth.

Min-Qian Luo, An Chen, Chengbin Huang, Min-Shan Guo, Ting Cai

Molecular Pharmaceutics

DOI

2024

Impact of Polymers on the Kinetics of the Solid-State Phase Transition of Piracetam Polymorphs.

Fanfan Fan, Yi Lu, Shuyuan Xu, Min-Shan Guo, Ting Cai

Molecular Pharmaceutics

DOI

2024

Advancements in nanoscale delivery systems: optimizing intermolecular interactions for superior drug encapsulation and precision release

Enpeng Dong, Qingqing Huo, Jie Zhang, Hanghang Han, Ting Cai, Dongfei Liu

Drug Delivery and Translational Research

DOI

2024

Zirconium-containing nanoscale coordination polymers for positron emission tomography and fluorescence-guided cargo delivery to triple-negative breast tumors

Yanping Li, Zi-Wen Pan, Yanjun Jiang, Yayun Peng, Ting Cai, Hao Hong, Xiao-feng Wang

Acta Biomaterialia

DOI

2023

多晶型对药物固体理化性质影响的研究进展

周丰涛，彭亚运，蔡挺

《中南药学》

2023

Advances in the development of amorphous solid dispersions: The role of polymeric carriers

Jie Zhang, Min-Shan Guo, Min-Qian Luo, Ting Cai

Asian Journal of Pharmaceutical Sciences

DOI

2023

Effect of organic acids on the solid-state polymorphic phase transformation of piracetam.

Fanfan Fan, Shuyuan Xu, Min-Shan Guo, Ting Cai

International journal of pharmaceutics

DOI

2023

Mechanistic Insight of Polymer Effects on the Kinetic of Solution-Mediated Phase Transformation of Nitrofurantoin Anhydrate to Monohydrate

Xi-Yan Wang, Xiao-Hong Ji, Ting Cai, Min-Shan Guo

Pharmaceutical Research

DOI

2023

Introducing the Molecular Pharmaceutics Virtual Special Issue on "Advances in Molecular Pharmaceutical Research from Asia".

Keisuke Ueda, Ting Cai, S. Biswas, Sun Hwa Kim

Molecular Pharmaceutics

DOI

2023

Solid-liquid phase equilibrium and thermodynamic properties analysis of Bazedoxifene acetate in fifteen kinds of mono-solvents

Zhuangzhuang Chen, Yuqing Ma, Ning Fang, Min Ge, Yuan Su, An Chen, Shuai Yu, Ting Cai

The Journal of Chemical Thermodynamics

DOI

2022

无定形固体分散体的溶出与吸收研究进展

吴昊旻，张杰，骆敏倩，蔡挺

《药学学报》

2022

纳米晶递药体系在肿瘤诊疗领域研究进展

凌祥，李尚飞，龙威，杨宇涵，蔡挺

《药学进展》

2022

Discovery of a new polymorph of clotrimazole through melt crystallization: Understanding nucleation and growth kinetics.

Jie Zhang, Min-Zhuo Liu, Mei-Xia Xu, Zhiguo Chen, Xucong Peng, Qiusheng Yang, Ting Cai, Zhihong Zeng

Journal of Chemical Physics

DOI

2022

Polymorphism of purpurin and low-level detection of the noncentrosymmetric form by second harmonic generation microscopy.

Jia Xu, An Chen, Ting Cai

Journal of Pharmacy and Science

DOI

2022

Impact of bile salt on solution-mediated phase transformation of pharmaceutical cocrystals: The importance of coformer release kinetics

Jiahui Chen, Minshan Guo, Runhui Fan, Yayun Peng, Ting Cai

Chemical Engineering Journal

DOI

2022

Modulation of Solid-State Chemical Stability of Gabapentin by Pyridinecarboxylic Acid

Min-Shan Guo, Xiaojie Sun, Shao-Zheng Zhang, Ting Cai

Pharmaceutical Research

DOI

2022

Co-Amorphous Formation of Simvastatin-Ezetimibe: Enhanced Physical Stability, Bioavailability and Cholesterol-Lowering Effects in LDLr−/−Mice

Shamuha Bahetibieke, S. Moinuddin, Asiya Baiyisaiti, Xiaoang Liu, Jie Zhang, Guo-Min Liu, Qin Shi, Ankang Peng, Jun Tao, Chang Di, Ting Cai, R. Qi

Pharmaceutics

DOI

2022

Melt Crystallization of Celecoxib-Carbamazepine Cocrystals with the Synchronized Release of Drugs

An Chen, Peishan Cai, Min-Qian Luo, Min-Shan Guo, Ting Cai

Pharmaceutical Research

DOI

2022

Amorphous phase-mediated crystallization of calcium pyrophosphate tetrahydrate: the role of alkaline earth metal ions

Shiwen Cui, Yuan Su, Ting Cai

CrystEngComm

DOI

2021

胰高血糖素样肽-1缓释微球技术进展

刘波，阮思达，蔡挺

《中国新药杂志》

2021

甘草素热转变产物鉴定及转变动力学研究

许柯，史长灿，金俊杰，蔡宝昌，蔡挺

《广东化工》

2021

双螺杆挤出湿法制粒工艺参数对颗粒可压片性和片剂溶出速度的影响

任沁，刘怡，祝旻卿，张杰，蔡挺

《中国医药工业杂志》

DOI

2021

Pharmaceutical cocrystals: A review of preparations, physicochemical properties and applications

Min-Shan Guo, Xiaojie Sun, Jia-Hui Chen, Ting Cai

Acta Pharmaceutica Sinica B

DOI

2021

Effect of polymeric excipients on nucleation and crystal growth kinetics of amorphous fluconazole.

Jie Zhang, Zheng-Yu Liu, Hao-Min Wu, Ting Cai

Biomaterials Science

DOI

2021

Structure–Thermomechanical Property Correlation in Polymorphic Molecular Crystals Probed by the Nanoindentation Technique

Yuan Su, Surojit Bhunia, Shuyuan Xu, A. Chen, C. M. Reddy, Ting Cai

DOI

2021

Crystallization kinetics and molecular dynamics of binary coamorphous systems of nimesulide and profen analogs.

Jie Zhang, Qin Shi, Tengfei Qu, Dong-Shan Zhou, Ting Cai

International journal of pharmaceutics

DOI

2020

基于γ-环糊精金属有机骨架的药物载体研究进展

薛茜，胡雄伟，蔡挺

《中国新药杂志》

2020

纳米金属有机框架材料在肿瘤诊疗领域的应用

张文婷，彭亚运，蔡挺

《广东化工》

2020

Development of liquiritigenin-phospholipid complex with the enhanced oral bioavailability.

Changcan Shi, K. Qin, Ke Xu, Aner Chen, Ting Cai, Bao-Chang Cai

Chinese Journal of Natural Medicines

DOI

2020

Enhanced Physical Stability and Synchronized Release of Febuxostat and Indomethacin in Coamorphous Solids

S. Moinuddin, Qin Shi, Jun Tao, Min-Shan Guo, Jie Zhang, Qian Xue, Sida Ruan, Ting Cai

AAPS PharmSciTech

DOI

2020

Melt Crystallization of Indomethacin Polymorphs in the Presence of Poly(ethylene oxide): Selective Enrichment of Polymer at the Crystal-Liquid Interface.

Jie Zhang, Qin Shi, Min-Shan Guo, Zheng-Yu Liu, Ting Cai

Molecular Pharmaceutics

DOI

2020

Solvent-Induced, Highly Unusual, Triangular-Shaped Organic Polar Crystal

Jia Xu, Shan Huang, Ting Cai

DOI

2020

Crack- and Bubble-Induced Fast Crystal Growth of Amorphous Griseofulvin

Qin Shi, Jun Tao, Jie Zhang, Yuan Su, Ting Cai

DOI

2019

黄酮类化合物共晶的研究进展

黄珊，蔡挺

《现代医药卫生》

2019

Impact of Polymer Enrichment at the Crystal-Liquid Interface on Crystallization Kinetics of Amorphous Solid Dispersions.

Jie Zhang, Qin Shi, Jun Tao, Ya-Yun Peng, Ting Cai

Molecular Pharmaceutics

DOI

2019

Facile Tuning of the Photoluminescence and Dissolution Properties of Phloretin through Cocrystallization

Shan Huang, Jia Xu, Ya-Yun Peng, Min-Shan Guo, Ting Cai

DOI

2019

Simultaneously Improving the Physicochemical Properties, Dissolution Performance, and Bioavailability of Apigenin and Daidzein by Co-Crystallization With Theophylline.

Shan Huang, Qian Xue, Jia Xu, Sida Ruan, Ting Cai

Journal of Pharmacy and Science

DOI

2018

Advances in coamorphous drug delivery systems

Qin Shi, S. Moinuddin, Ting Cai

Acta Pharmaceutica Sinica B

DOI

2018

Long-Acting Release Microspheres Containing Novel GLP-1 Analog as an Antidiabetic System.

Sida Ruan, Yuan-Yuan Gu, Bo Liu, Huashan Gao, Xiongwei Hu, Haiping Hao, Liang Jin, Ting Cai

Molecular Pharmaceutics

DOI

2018

Enhanced Crystal Nucleation in Glass-Forming Liquids by Tensile Fracture in the Glassy State

Yuan Su, Lian Yu, Ting Cai

Crystal Growth & Design

DOI

2018

Polymorphism of griseofulvin: concomitant crystallization from the melt and a single crystal structure of a metastable polymorph with anomalously large thermal expansion.

Yuan Su, Jia Xu, Qin Shi, Lian Yu, Ting Cai

Chemical Communications

DOI

2017

异甘草素共晶的热力学研究

黄雨婷，迟宗良，秦昆明，范孟雪，胡静，蔡宝昌，蔡挺

《中国新药杂志》

2017

Fast Surface Diffusion and Crystallization of Amorphous Griseofulvin.

Chengbin Huang, Shigang Ruan, Ting Cai, Lian Yu

Journal of Physical Chemistry B

DOI

2017

Selective Acceleration of Crystal Growth of Indomethacin Polymorphs by Low-Concentration Poly(ethylene oxide).

Qin Shi, Jie Zhang, Chen Zhang, Jing Jiang, Jun Tao, Dong-Shan Zhou, Ting Cai

Molecular Pharmaceutics

DOI

2017

Effect of Low-Concentration Polymers on Crystal Growth in Molecular Glasses: A Controlling Role for Polymer Segmental Mobility Relative to Host Dynamics.

Chengbin Huang, C. Powell, Ye Sun, Ting Cai, Lian Yu

Journal of Physical Chemistry B

DOI

2017

Facile formation of co-amorphous atenolol and hydrochlorothiazide mixtures via cryogenic-milling: Enhanced physical stability, dissolution and pharmacokinetic profile.

S. Moinuddin, Sida Ruan, Yuting Huang, Qin Gao, Qin Shi, B. Cai, Ting Cai

International journal of pharmaceutics

DOI

2017

Acceleration of Crystal Growth of Amorphous Griseofulvin by Low-Concentration Poly(ethylene oxide): Aspects of Crystallization Kinetics and Molecular Mobility.

Qin Shi, Chen Zhang, Yuan Su, Jie Zhang, Dong-Shan Zhou, Ting Cai

Molecular Pharmaceutics

DOI

2017

Nanostructures and Dynamics of Isochorically Confined Amorphous Drug Mediated by Cooling Rate, Interfacial, and Intermolecular Interactions.

Chen Zhang, Ye Sha, Yue Zhang, Ting Cai, Lin-Ling Li, Dong-Shan Zhou, Xiaoliang Wang, G. Xue

Journal of Physical Chemistry B

DOI

2016

甘草素注射液制备工艺研究

黄雨婷，顾杰，姚仲青，蔡云清，迟宗良，秦昆明，蔡挺，蔡宝昌

《中国药学杂志》

2016

药物共晶筛选技术的研究进展

黄雨婷，徐嘉，迟宗良，范孟雪，秦昆明，蔡挺，蔡宝昌

《国际药学研究杂志》

2016

薬物共晶スクリーニング技術の研究進展【JST・京大機械翻訳】

Yu-Ting Huang, Jia Xu, Zong-Liang Chi, Meng-Xue Fan, Kun-Ming Qin, Ting Cai, Bao-Chang Cai

2016

Fast Crystal Growth of Amorphous Griseofulvin: Relations between Bulk and Surface Growth Modes

Qin Shi, Ting Cai

DOI

2016

Cocrystals of isoliquiritigenin with enhanced pharmacokinetic performance

Jia Xu, Yuting Huang, Sida Ruan, Zong-Liang Chi, Kun-Ming Qin, Bao-Chang Cai, Ting Cai

DOI

2014

Fast Surface Crystal Growth on Molecular Glasses and Its Termination by the Onset of Fluidity.

Mariko Hasebe, Daniele Musumeci, C. Powell, Ting Cai, E. Gunn, Lei Zhu, Lian Yu

Journal of Physical Chemistry B

DOI

2013

Low-concentration polymers inhibit and accelerate crystal growth in organic glasses in correlation with segmental mobility.

C. Powell, Ting Cai, Mariko Hasebe, E. Gunn, P. Gao, Geoff G. Z. Zhang, Yu-Chuan Gong, Lian Yu

Journal of Physical Chemistry B

DOI

2012

Polymorphism of Nifedipine: Crystal Structure and Reversible Transition of the Metastable β Polymorph

E. Gunn, I. Guzei, Ting Cai, Yu Lian

DOI

2012

Stability of Amorphous Pharmaceutical Solids: Crystal Growth Mechanisms and Effect of Polymer Additives

Ye Sun, Lei Zhu, Tian Wu, Ting Cai, E. Gunn, Lian Yu

AAPS Journal

DOI

2011

Crystallization of Organic Glasses: Effects of Polymer Additives on Bulk and Surface Crystal Growth in Amorphous Nifedipine

Ting Cai, Lei Zhu, Lian Yu

Pharmaceutical Research

DOI

会议论文

2016

Crystal Growth Behaviors and Mechanisms of Amorphous Griseofulvin

Qin Shi, Yuan Su, Jie Zhang, 蔡挺

《2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会工作年会、国际控释协会中国分会2016年学术年会》

研究方向

药剂学与制剂工程药物晶型及固态化学难溶药物/缓控释长效制剂药品质量控制与先进制造

此主页由公开资料整理，尚未经学者本人认领。