陈钧｜复旦大学｜学者主页

百晓学者学者目录

精选作品

期刊论文

2018

Follicle-stimulating hormone peptide-conjugated nanoparticles for targeted shRNA delivery lead to effective gro-α silencing and antitumor activity against ovarian cancer

Shanshan Hong, Ming-Xing Zhang, Meng Zhang, Yi Yu, Jun Chen, Xiaoyan Zhang, Congjian Xu

Drug Delivery

DOI

2018

Transcriptional control of the MUC16 promoter facilitates follicle-stimulating hormone peptide-conjugated shRNA nanoparticle-mediated inhibition of ovarian carcinoma in vivo

Ming-Xing Zhang, Shanshan Hong, Qingqing Cai, Meng Zhang, Jun Chen, Xiaoyan Zhang, Congjian Xu

Drug Delivery

DOI

2018

Leukocyte-derived biomimetic nanoparticulate drug delivery systems for cancer therapy

Yukun Huang, Xiaoling Gao, Jun Chen

Acta Pharmaceutica Sinica B

DOI

2015

Pharmacokinetics of isoforskolin after administration via different routes in guinea pigs

Tingting Feng, Yong Li, Jun Chen, Yong Chen, Jianming Huang, Weiyu Weng

Xenobiotica

DOI

2015

Enhancing Glioblastoma-Specific Penetration by Functionalization of Nanoparticles with an Iron-Mimic Peptide Targeting Transferrin/Transferrin Receptor Complex

Ting Kang, Mengyin Jiang, Di Jiang, Xingye Feng, Jianhui Yao, Qingxiang Song, Hongzhuan Chen, Xiaoling Gao, Jun Chen

Molecular Pharmaceutics

DOI

2014

UPA-sensitive ACPP-conjugated nanoparticles for multi-targeting therapy of brain glioma

Bo Zhang, Yujie Zhang, Ziwei Liao, Ting Jiang, Jingjing Zhao, Yanyan Tuo, Xiaojian She, Shun Shen, Jun Chen, Qizhi Zhang, Xinguo Jiang, Yu Hu, Zhiqing Pang

Biomaterials

DOI

2014

Harnessing the Capacity of Cell-Penetrating Peptides for Drug Delivery to the Central Nervous System

Ting Kang, Xiaoling Gao, Jun Chen

Current Pharmaceutical Biotechnology

DOI

2014

Facilitated brain delivery of poly (ethylene glycol)–poly (lactic acid) nanoparticles by microbubble-enhanced unfocused ultrasound

Lei Yao, Qingxiang Song, Wenkun Bai, Jizhen Zhang, Deyu Miao, Mengyin Jiang, Yu Wang, Zhiyong Shen, Quanyin Hu, Xiao Qin Gu, Meng Huang, Gang Zheng, Xiaoling Gao, Bing Quan Hu, Jun Chen, Hongzhuan Chen

Biomaterials

DOI

2014

iNGR-modified PEG-PLGA nanoparticles that recognize tumor vasculature and penetrate gliomas

Ting Kang, Xiaoling Gao, Quanyin Hu, Di Jiang, Xingye Feng, Xue Zhang, Qingxiang Song, Lei Yao, Meng Huang, Xinguo Jiang, Zhiqing Pang, Hongzhuan Chen, Jun Chen

Biomaterials

DOI

2013

Lactoferrin-modified PEG-co-PCL nanoparticles for enhanced brain delivery of NAP peptide following intranasal administration

Zhongyang Liu, Mengyin Jiang, Ting Kang, Deyu Miao, Guangzhi Gu, Qingxiang Song, Lei Yao, Quanyin Hu, Yifan Tu, Zhiqing Pang, Hongzhuan Chen, Xinguo Jiang, Xiaoling Gao, Jun Chen

Biomaterials

DOI

2013

Targeted gene silencing using a follicle-stimulating hormone peptide-conjugated nanoparticle system improves its specificity and efficacy in ovarian clear cell carcinoma in vitro

Shanshan Hong, Xiaoyan Zhang, Jun Chen, Jiabing Zhou, Yufang Zheng, Congjian Xu

Journal of Ovarian Research

DOI

2013

Activatable Cell Penetrating Peptide-Conjugated Nanoparticles with Enhanced Permeability for Site-Specific Targeting Delivery of Anticancer Drug

Huimin Xia, Guangzhi Gu, Quanyin Hu, Zhongyang Liu, Mengyin Jiang, Ting Kang, Deyu Miao, Qingxiang Song, Lei Yao, Yifan Tu, Hongzhuan Chen, Xiaoling Gao, Jun Chen

Bioconjugate Chemistry

DOI

2013

Incorporation of lapatinib into core–shell nanoparticles improves both the solubility and anti-glioma effects of the drug

Huile Gao, Yuchen Wang, Chen Chen, Jun Chen, Yan Wei, Shilei Cao, Xinguo Jiang

International Journal of Pharmaceutics

DOI

2013

Co-administration of Dual-Targeting Nanoparticles with Penetration Enhancement Peptide for Antiglioblastoma Therapy

Deyu Miao, Mengyin Jiang, Zhongyang Liu, Guangzhi Gu, Quanyin Hu, Ting Kang, Qingxiang Song, Lei Yao, Wei Li, Xiaoling Gao, Mingjiang Sun, Jun Chen

Molecular Pharmaceutics

DOI

2013

LDLR-mediated peptide-22-conjugated nanoparticles for dual-targeting therapy of brain glioma

Bo Zhang, Xiyang Sun, Heng Mei, Yu Wang, Ziwei Liao, Jun Chen, Qizhi Zhang, Yu Hu, Zhiqing Pang, Xinguo Jiang

Biomaterials

DOI

2013

B6 Peptide-Modified PEG-PLA Nanoparticles for Enhanced Brain Delivery of Neuroprotective Peptide

Zhongyang Liu, Xiaoling Gao, Ting Kang, Mengyin Jiang, Deyu Miao, Guangzhi Gu, Quanyin Hu, Qingxiang Song, Lei Yao, Yifan Tu, Hongzhuan Chen, Xinguo Jiang, Jun Chen

Bioconjugate Chemistry

DOI

2013

The influence of the penetrating peptide iRGD on the effect of paclitaxel-loaded MT1-AF7p-conjugated nanoparticles on glioma cells

Guangzhi Gu, Xiaoling Gao, Quanyin Hu, Ting Kang, Zhongyang Liu, Mengyin Jiang, Deyu Miao, Qingxiang Song, Lei Yao, Yifan Tu, Zhiqing Pang, Hongzhuan Chen, Xinguo Jiang, Jun Chen

Biomaterials

DOI

2012

Penetratin-functionalized PEG–PLA nanoparticles for brain drug delivery

Huimin Xia, Xiaoling Gao, Guangzhi Gu, Zhongyang Liu, Quanyin Hu, Yifan Tu, Qingxiang Song, Lei Yao, Zhiqing Pang, Xinguo Jiang, Jun Chen, Hongzhuan Chen

International Journal of Pharmaceutics

DOI

2012

Intracellular delivery mechanism and brain delivery kinetics of biodegradable cationic bovine serum albumin-conjugated polymersomes

Xinguo Jiang, Zhiqing Pang, Heng Mei, Huile Gao, Jun Chen, Shun Shen, Bo Zhang, Jinfeng Ren, Liangran Guo, Yong jun Qian

International Journal of Nanomedicine

DOI

2012

Mechanisms of transcellular transport of wheat germ agglutinin-functionalized polymeric nanoparticles in Caco-2 cells

Qingxiang Song, Lei Yao, Meng Huang, Quanyin Hu, Qin Lu, Bingxian Wu, Hong Yan Qi, Zhengxing Rong, Xinguo Jiang, Xiaoling Gao, Jun Chen, Hongzhuan Chen

Biomaterials

DOI

2012

F3 peptide-functionalized PEG-PLA nanoparticles co-administrated with tLyp-1 peptide for anti-glioma drug delivery

Quanyin Hu, Guangzhi Gu, Zhongyang Liu, Mengyin Jiang, Ting Kang, Deyu Miao, Yifan Tu, Zhiqing Pang, Qingxiang Song, Lei Yao, Huimin Xia, Hongzhan Chen, Xinguo Jiang, Xiaoling Gao, Jun Chen

Biomaterials

DOI

2011

Co-delivery of pEGFP-hTRAIL and paclitaxel to brain glioma mediated by an angiopep-conjugated liposome

Xiyang Sun, Zhiqing Pang, Hongxing Ye, Bo Qiu, Liangran Guo, Jingwei Li, Jinfeng Ren, Yong jun Qian, Qizhi Zhang, Jun Chen, Xinguo Jiang

Biomaterials

DOI

2011

Low molecular weight protamine-functionalized nanoparticles for drug delivery to the brain after intranasal administration

Huimin Xia, Xiaoling Gao, Guangzhi Gu, Zhongyang Liu, Ni Zeng, Quanyin Hu, Qingxiang Song, Lei Yao, Zhiqing Pang, Xinguo Jiang, Jun Chen, Hongzhuan Chen

Biomaterials

DOI

2011

Aptamer-functionalized PEG–PLGA nanoparticles for enhanced anti-glioma drug delivery

Jianwei Guo, Xiaoling Gao, Lina Su, Huimin Xia, Guangzhi Gu, Zhiqing Pang, Xinguo Jiang, Lei Yao, Jun Chen, Hongzhuan Chen

Biomaterials

DOI

2011

Targeting the brain with PEG–PLGA nanoparticles modified with phage-displayed peptides

Jingwei Li, Liang Feng, Li Fan, Yuan Zha, Liangran Guo, Qizhi Zhang, Jun Chen, Zhiqing Pang, Yuchen Wang, Xinguo Jiang, Victor Chi-Min Yang, Longping Wen

Biomaterials

DOI

2011

Brain delivery and cellular internalization mechanisms for transferrin conjugated biodegradable polymersomes

Zhiqing Pang, Huile Gao, Yuan Yu, Jun Chen, Liangran Guo, Jinfeng Ren, Ziyi Wen, Jinghan Su, Xinguo Jiang

International Journal of Pharmaceutics

DOI

2011

Enhanced Intracellular Delivery and Chemotherapy for Glioma Rats by Transferrin-Conjugated Biodegradable Polymersomes Loaded with Doxorubicin

Zhiqing Pang, Huile Gao, Yuan Yu, Liangran Guo, Jun Chen, Shuaiqi Pan, Jinfeng Ren, Ziyi Wen, Xinguo Jiang

Bioconjugate Chemistry

DOI

2009

Preparation of nasal temperature-sensitive in situ gel ofRadix Bupleuriand evaluation of the febrile response mechanism

En Chen, Jun Chen, Shilei Cao, Qizhi Zhang, Xinguo Jiang

Drug Development and Industrial Pharmacy

DOI

2008

Preparation and brain delivery property of biodegradable polymersomes conjugated with OX26

Zhiqing Pang, Wei Lü, Huile Gao, Kaili Hu, Jun Chen, Chaolin Zhang, Xiaoling Gao, Xinguo Jiang, Cuiqing Zhu

Journal of Controlled Release

DOI

2006

PEG化聚乙烯亚胺作为非病毒基因给药载体的研究

蔡佳，陈钧，黄平，申云帆，蒋新国

《中国医药工业杂志》

2005

Determination of apovincaminic acid in human plasma by high-performance liquid chromatography using solid-phase extraction and ultraviolet detection

Jun Chen, Jia Xi Cai, Weixing Tao, Mei Ni, Shilei Cao, Xinguo Jiang

Journal of Chromatography B

DOI

2004

Bioequivalence evaluation of two rabeprazole enteric coated formulations in healthy Chinese volunteers

Jun Chen, Wen Ming Jiang, Xiao Ling Gao, Xinguo Jiang, Qi Zhi Zhang, Zhao Zheng

European Journal of Drug Metabolism and Pharmacokinetics

DOI

会议论文

2018

基于细胞膜的仿生纳米技术应用于肿瘤治疗研究

陈钧

《2018年第十二届中国药物制剂大会》

2016

Neovasculature and circulating tumor cells dual-targeting nanoparticles for the treatment of the highly-invasive breast cancer

姚建辉，Jun Chen

《2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会工作年会、国际控释协会中国分会2016年学术年会》

2014

卵泡刺激素受体介导并由MUC16启动子调控的卵巢癌靶向递药系统构建

张晓燕，洪珊珊，蔡青青，陈武炼，陈钧，徐丛剑

《遵循诊疗规范、鼓励临床试验——第八届中国肿瘤内科大会、第三届中国肿瘤医师大会、中国抗癌协会肿瘤临床化疗专业委员会2014年学术年会》

2013

Dual Targeting and Penetration Enhancement-based Strategies for Anti-Glioma Drug Delivery

陈钧

《2013年中国药物制剂大会》

2007

OX26-聚合泡囊的制备及其脑内递药特性研究

庞志清，高会乐，陈钧，胡凯莉，蒋新国

《第三届国际药物制剂论坛》

研究方向

靶向药物递送系统药物制剂药动学与成药性评价药物新剂型与新制剂肿瘤穿透纳米递送

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