郜原｜甘肃农业大学｜学者主页

2026

FGF21和β-klotho蛋白在双峰驼组织中的表达分布研究

嵇旺晔，赵淑琴，吴世朋，侯纪宝，张丽丽，李建飞，郜原

《甘肃农业大学学报》

DOI

2026

The regulatory mechanism of circadian clock gene Cry on estrogen secretion in Bactrian camels

Shipeng Wu, Shuqin Zhao, Shuai Ji, Jianfei Li, Yuan Gao, Jibao Hou, Yuting Fang

Biology of Reproduction

DOI

2025

生物化学课程教学中学习兴趣的激发策略探究

刘敏瑞，郜原

《西昌学院学报(自然科学版)》

DOI

2025

农业院校动物生物化学实验教学改革实践与探索

刘敏瑞，刘霞，齐兴娥，许富强，郜原，司怀军

《生物学杂志》

2025

Fatty Acid Metabolism via CPT1A Supports Poll Gland Function and Rutting Activities in Male Bactrian Camels

Qi Ma, Bohao Zhang, Bin Zhou, Quanwei Zhang, Yuan Gao

Biomolecules

DOI

2025

Role of GATM/creatine as energy reserves in the poll gland and rutting activities in male Bactrian camel

Zhixiong Tang, Jianfu Li, Bin Zhou, Bohao Zhang, Junjun Zhang, Shuru Cheng, Weitao Dong, Yong Zhang, Xingxu Zhao, Quanwei Zhang, Yuan Gao

International Journal of Biological Macromolecules

DOI

2025

Development of an iridium complex fluorescent probe for FGF21 protein labeling and tracking

Lili Zhang, Shaobo Du, Wangye Ji, Jianfei Li, Ruilin Ma, Dexiang Yan, Yuhao Niu, Shuqin Zhao, Jiaxi Ru, Yuan Gao

Scientific Reports

DOI

2025

Establishment of a Direct Competitive ELISA for Camel FGF21 Detection

Yuxuan Yang, Hongbin Yuan, Yunjuan Jiao, Shuqin Zhao, Yuanfang Fu, Xingwen Bai, Zengjun Lu, Yuan Gao

Veterinary Sciences

DOI

2025

Melatonin modulated GPX5 and PTGDS expression in Bactrian camel epididymis mainly via receptor MT1

Shuqin Zhao, Shipeng Wu, Shuai Ji, Yaxuan Han, Zhen Yang, Yuan Gao

Biology of Reproduction

DOI

2024

骆驼FGF21蛋白的原核表达及其多克隆抗体的制备与鉴定

杨宇轩，袁红，焦云娟，王涛，高洁，李坤，李平花，孙普，卢曾军，白兴文，郜原

《中国兽医科学》

2024

混合式教学模式在生理学课程中的探索与实践

赵禹，郜原，张全伟

《畜牧兽医杂志》

2024

基于产学研一体化培养的动物生理学实验教学设计研究

赵禹，郜原，张全伟

《吉林农业科技学院学报》

2024

Withdrawn: Camel FGF21 Protein Enhances FGF21 Signaling and its Targeted Compounds Screening

Yuan Gao, Fang Yong, Wangye Ji, Lili Zhang, Jibao Hou, Ruilin Ma, Shuqin Zhao, Huizhen Ge, Xiaoyu Wu

Current Pharmaceutical Design

DOI

2024

Exploring the Mechanism of H2S Synthesis in Male Bactrian Camel Poll Glands Based on Data Independent Acquisition Proteomics and Non-Targeted Metabolomics

Bao Yuan, Quanwei Zhang, Bohao Zhang, Jianfu Li, Wenli Chen, Yu Juan Zhao, Weitao Dong, Yong Zhang, Xingxu Zhao, Yuan Gao

International Journal of Molecular Sciences

DOI

2024

Exploring Hollow Mesoporous Silica Nanoparticles as a Nanocarrier in the Delivery of Foot-And-Mouth Disease Virus-like Particle Vaccines

Jiaxi Ru, Yu Chen, Siyi Tao, Shaobo Du, Chao Liang, Zhidong Teng, Yuan Gao

ACS Applied Bio Materials

DOI

2023

野骆驼基因组密码子偏好性分析

赵禹，赵如莉，郜原

《中国畜牧兽医》

2023

O-KEPT教学模式的构建及在生物化学课程教学中的实践

郜原，武小椿，刘敏瑞，齐兴娥，韩江媛，司怀军

《生物学杂志》

2023

Analysis of Functional Promoter of Camel FGF21 Gene and Identification of Small Compounds Targeting FGF21 Protein

Fang Yong, Meilin Yan, Lili Zhang, Wangye Ji, Shuqin Zhao, Yuan Gao

Veterinary Sciences

DOI

2023

Gas/Liquid Chromatography–Mass Spectrometry Analysis of Key Functional Substances Regulating Poll Gland Secretion in Male Camels during Seasonal Estrus

Lijun Dai, Bao Yuan, Bohao Zhang, Wenli Chen, Xixue Yuan, Xinhong Liu, Yuan Gao, Yong Zhang, Quanwei Zhang, Xingxu Zhao

Animals

DOI

2023

Construction and Characterization of Immortalized Fibroblast Cell Line from Bactrian Camel

Meilin Yan, Fang Yong, Wangye Ji, Lili Zhang, Shuqin Zhao, Yuan Gao

Life

DOI

2023

MiR-361 and miR-34a suppress foot-and-mouth disease virus proliferation by activating immune response signaling in PK-15 cells

Yuan Gao, Fang Yong, Meilin Yan, Yanquan Wei, Xiaochun Wu

Veterinary Microbiology

DOI

2023

Localization of FGF21 Protein and Lipid Metabolism-Related Genes in Camels

Yuan Gao, Shuqin Zhao, Wangdong Zhang, Huaping Tang, Meilin Yan, Fang Yong, Xu Bai, Xiaochun Wu, Yong Zhang, Quanwei Zhang

Life

DOI

2023

Application Progress of the Single Domain Antibody in Medicine

Huaping Tang, Yuan Gao, Jiangyuan Han

International Journal of Molecular Sciences

DOI

2022

细胞永生化的研究进展

闫美淋，雍芳，赵淑琴，郜原

《畜牧与兽医》

2022

成纤维细胞生长因子21的功能研究进展

雍芳，闫美淋，赵淑琴，郜原

《生命的化学》

DOI

2022

松果体外褪黑素研究进展

杨王浩，赵淑琴，闫美淋，雍芳，陈华涛，郜原

《动物医学进展》

2022

“团队化引导”在大学班集体建设中的实践——高校青年教师班主任生涯发展之路

郜原，张岁玲，杨德龙，岳效飞，孙露，陈正军，罗攀

《高教学刊》

2022

High Concentration of FBS Can Save mTOR Down-Regulation Caused by Mycoplasmas bovis Infection

Xiaochun Wu, Jinrui Ma, Shangdong Jia, Xudong Zhang, Xinlan Zhang, Zhen An, Yanquan Wei, Xiaoyong Xing, Fengqin Wen, Yuan Gao, Shijun Bao

Veterinary Sciences

DOI

2022

CTH/H2S Regulates LPS-Induced Inflammation through IL-8 Signaling in MAC-T Cells

Ting Lin, Xu Bai, Yuan Gao, Bohao Zhang, Jun Shi, Bao Yuan, Wenli Chen, Jianfu Li, Yong Zhang, Quanwei Zhang, Xingxu Zhao

International Journal of Molecular Sciences

DOI

2022

Toll-like Receptor 2 Is Associated with the Immune Response, Apoptosis, and Angiogenesis in the Mammary Glands of Dairy Cows with Clinical Mastitis

Xu Bai, Xueying Wang, Ting Lin, Weitao Dong, Yuan Gao, Peng Ji, Yong Zhang, Xingxu Zhao, Quanwei Zhang

International Journal of Molecular Sciences

DOI

2022

Melatonin Receptors: A Key Mediator in Animal Reproduction

Yuan Gao, Shuqin Zhao, Yong Zhang, Quanwei Zhang

Veterinary Sciences

DOI

2021

骆驼褪黑素受体的结构预测及进化分析

杨王浩，袁宝，王莉，赵宸，郜原

《中兽医医药杂志》

DOI

2021

多种教学手段在动物生物化学教学中的应用

刘敏瑞，刘霞，郜原，杨孝朴

《生命的化学》

DOI

2021

“课程思政”在生物类专业课程混合式教学中的实践探索

郜原，张岁玲，陈正军，罗攀，杨德龙

《吕梁学院学报》

2021

cAMP/PKA/CREB signaling pathway-mediated effects of melatonin receptor genes on clock gene expression in Bactrian camel ovarian granulosa cells

Siwen Zhao, Yuan Gao, Yong Zhang, X.-P. Yang, Z. Yang

Domestic Animal Endocrinology

DOI

2020

基于THEOL平台的生物化学课程混合式教学改革实践

郜原，武小椿，刘霞，李龙凤，杨德龙，司怀军

《生物学杂志》

2020

“以学生为中心”的生物类专业课程在线教学设计与实践

郜原，张岁玲，武小椿，杨德龙，司怀军

《生物学杂志》

2020

The in vitro effects of melatonin and Cry gene on the secretion of estradiol from camel ovarian granulosa cells

Shuqin Zhao, Yong Zhang, Yuan Gao, Yang Xiao-pu, Yang Zhen, Yang Zhi-Jie

Domestic Animal Endocrinology

DOI

2020

Reporter gene knock-in into Marc-145 cells using CRISPR/Cas9-mediated homologous recombination

Yanyan Chang, Junjun Shao, Yuan Gao, Wei Liu, Zhan Gao, Yonghao Hu, Huiyun Chang

Biotechnology Letters

DOI

2019

Melatonin receptor depletion suppressed hCG-induced testosterone expression in mouse Leydig cells

Yuan Gao, Xiaochun Wu, Shuqin Zhao, Yujun Zhang, Hailong Ma, Zhen Yang, Wanghao Yang, Chen Zhao, Li Wang, Quanwei Zhang

Cellular & Molecular Biology Letters

DOI

2018

Corrigendum: Foot-and-mouth disease virus infection stimulates innate immune signaling in the mouse macrophage RAW 264.7 cells

Xiaoying Zhi, Jianliang Lv, Yanquan Wei, Yuan Gao, Ping Du, Yanyan Chang, Yun Zhang, Run Wu, Huichen Guo

Canadian Journal of Microbiology

DOI

2018

Production of functional double‐stranded RNA using a prokaryotic expression system in Escherichia coli

Zhengjun Chen, Jindian He, Pan Luo, Xiangkai Li, Yuan Gao

MicrobiologyOpen

DOI

2017

Foot-and-mouth disease virus infection stimulates innate immune signaling in the mouse macrophage RAW 264.7 cells

Xiaoying Zhi, Jianliang Lv, Yanquan Wei, Ping Du, Yanyan Chang, Yun Zhang, Yuan Gao, Run Wu

Canadian Journal of Microbiology

DOI

2016

口蹄疫病毒诱导PK-15细胞发生自噬的研究

范许许，郜原，郭慧琛，孙世琪

《安徽农业科学》

2016

CD44受体分子对口蹄疫病毒感染的影响

谷玲军，郭慧琛，郜原，韩世充，孙世琪，杨玉莹

《中国兽医科学》

DOI

2012

猪繁殖与呼吸综合征病毒相关猪microRNA的初步筛选

郜原，薄联锋，武小椿，孙柏，温俊歌，孙岩，徐志坤，张德礼

《中国兽医杂志》

2012

维甲酸促进小鼠F9细胞中STAT1的反式激活作用

吴海波，吴勇延，郜原，杜娟，艾志营，郭泽坤

《中国生物化学与分子生物学报》

2011

抑制猪繁殖与呼吸综合征病毒3’UTR的猪microRNA体外筛选

郜原

《西北农林科技大学》

2011

鸡BCL10基因的克隆与表达

孙柏，李燕丽，张亚杰，薄联锋，郜原，张德礼

《中国兽医学报》

2011

猪Akirin2基因的定位及其影响IL-1β和IL-6 mRNA表达的研究

徐志坤，薄联峰，温俊歌，孙岩，郜原，吴江，张德礼

《中国兽医杂志》

2011

猪新基因P58IPK的分子克隆、原核表达及其多克隆抗体的制备

温俊歌，宋豪，孙岩，郜原，徐志坤，薄联锋，张德礼

《细胞与分子免疫学杂志》

2011

Thr-Ser-Ser位点对猪BCL10募集功能的影响

薄联锋，徐志坤，郜原，孙岩，温俊歌，张德礼

《中国兽医学报》

2011

猪淋巴结PKR基因的克隆与体外初步表达

孙岩，胡健，温俊歌，郜原，薄联锋，徐志坤，吴耀丽，张德礼

《西北农林科技大学学报(自然科学版)》

精选作品

期刊论文

FGF21和β-klotho蛋白在双峰驼组织中的表达分布研究

The regulatory mechanism of circadian clock gene Cry on estrogen secretion in Bactrian camels

生物化学课程教学中学习兴趣的激发策略探究

农业院校动物生物化学实验教学改革实践与探索

Fatty Acid Metabolism via CPT1A Supports Poll Gland Function and Rutting Activities in Male Bactrian Camels

Role of GATM/creatine as energy reserves in the poll gland and rutting activities in male Bactrian camel

Development of an iridium complex fluorescent probe for FGF21 protein labeling and tracking

Establishment of a Direct Competitive ELISA for Camel FGF21 Detection

Melatonin modulated GPX5 and PTGDS expression in Bactrian camel epididymis mainly via receptor MT1

骆驼FGF21蛋白的原核表达及其多克隆抗体的制备与鉴定

混合式教学模式在生理学课程中的探索与实践

基于产学研一体化培养的动物生理学实验教学设计研究

Withdrawn: Camel FGF21 Protein Enhances FGF21 Signaling and its Targeted Compounds Screening

Exploring the Mechanism of H2S Synthesis in Male Bactrian Camel Poll Glands Based on Data Independent Acquisition Proteomics and Non-Targeted Metabolomics

Exploring Hollow Mesoporous Silica Nanoparticles as a Nanocarrier in the Delivery of Foot-And-Mouth Disease Virus-like Particle Vaccines

野骆驼基因组密码子偏好性分析

O-KEPT教学模式的构建及在生物化学课程教学中的实践

Analysis of Functional Promoter of Camel FGF21 Gene and Identification of Small Compounds Targeting FGF21 Protein

Gas/Liquid Chromatography–Mass Spectrometry Analysis of Key Functional Substances Regulating Poll Gland Secretion in Male Camels during Seasonal Estrus

Construction and Characterization of Immortalized Fibroblast Cell Line from Bactrian Camel

MiR-361 and miR-34a suppress foot-and-mouth disease virus proliferation by activating immune response signaling in PK-15 cells

Localization of FGF21 Protein and Lipid Metabolism-Related Genes in Camels

Application Progress of the Single Domain Antibody in Medicine

细胞永生化的研究进展

成纤维细胞生长因子21的功能研究进展

松果体外褪黑素研究进展

“团队化引导”在大学班集体建设中的实践——高校青年教师班主任生涯发展之路

High Concentration of FBS Can Save mTOR Down-Regulation Caused by Mycoplasmas bovis Infection

CTH/H2S Regulates LPS-Induced Inflammation through IL-8 Signaling in MAC-T Cells

Toll-like Receptor 2 Is Associated with the Immune Response, Apoptosis, and Angiogenesis in the Mammary Glands of Dairy Cows with Clinical Mastitis

Melatonin Receptors: A Key Mediator in Animal Reproduction

骆驼褪黑素受体的结构预测及进化分析

多种教学手段在动物生物化学教学中的应用

“课程思政”在生物类专业课程混合式教学中的实践探索

cAMP/PKA/CREB signaling pathway-mediated effects of melatonin receptor genes on clock gene expression in Bactrian camel ovarian granulosa cells

基于THEOL平台的生物化学课程混合式教学改革实践

“以学生为中心”的生物类专业课程在线教学设计与实践

The in vitro effects of melatonin and Cry gene on the secretion of estradiol from camel ovarian granulosa cells

Reporter gene knock-in into Marc-145 cells using CRISPR/Cas9-mediated homologous recombination

Melatonin receptor depletion suppressed hCG-induced testosterone expression in mouse Leydig cells

Corrigendum: Foot-and-mouth disease virus infection stimulates innate immune signaling in the mouse macrophage RAW 264.7 cells

Production of functional double‐stranded RNA using a prokaryotic expression system in Escherichia coli

Foot-and-mouth disease virus infection stimulates innate immune signaling in the mouse macrophage RAW 264.7 cells

口蹄疫病毒诱导PK-15细胞发生自噬的研究

CD44受体分子对口蹄疫病毒感染的影响

猪繁殖与呼吸综合征病毒相关猪microRNA的初步筛选

维甲酸促进小鼠F9细胞中STAT1的反式激活作用

抑制猪繁殖与呼吸综合征病毒3’UTR的猪microRNA体外筛选

鸡BCL10基因的克隆与表达

猪Akirin2基因的定位及其影响IL-1β和IL-6 mRNA表达的研究

猪新基因P58IPK的分子克隆、原核表达及其多克隆抗体的制备

Thr-Ser-Ser位点对猪BCL10募集功能的影响

猪淋巴结PKR基因的克隆与体外初步表达

研究方向