梁高林｜东南大学｜学者主页

2026

Fibroblast activation protein-α-triggered photoacoustic signal “on” for pancreatic tumor imaging

Runqun Tang, Ziyi Zhang, Liangxi Zhu, Haidong Xu, Tianyi Zhang, Yang Yang, Wenjun Zhan, Sisi Zhou, Gaolin Liang

Biosensors and Bioelectronics

DOI

2026

An OGP binding protein complex-mimicking peptide hydrogel for dental pulp regeneration

Ying Sha, Wenjun Zhan, Ziyi Qin, Siyi Sun, Jie Li, Yichen Zong, Mengyuan Li, Fei Jiang, Gaolin Liang, Guangdong Zhang

Biomaterials

DOI

2026

“Turn-On” Nanoprobe for Stage-Differential Imaging of Inflammatory Bowel Disease

Xinru Kong, Junya Zhang, Qiaochu Jiang, Fan Xing, Sisi Zhou, Gaolin Liang

Analytical Chemistry

DOI

2026

Matrix Metalloproteinase-9-Activated Dually-Quenched Fluorescence Nanoprobe for Sensitive Imaging of Rheumatoid Arthritis

Haidong Xu, Xiaotong Cheng, Qiaochu Jiang, Runqun Tang, Xiaoyang Liu, Xiancheng Fu, Xianbao Sun, Gaolin Liang

Analytical Chemistry

DOI

2026

An Enterokinase-Activatable Bioluminescent Probe for In Vivo Tumor Imaging

Xiaotong Cheng, Guowei Liang, Tiantian Xia, Haidong Xu, Binbin Wang, Gaolin Liang

Analytical Chemistry

DOI

2026

In Situ Peptide Assembly for Cancer Therapy

Guowei Liang, Guowei Liang, Xianbao Sun, Yu Ma, Tiantian Xia, Xiaotong Cheng, Gaolin Liang, Gaolin Liang

Angewandte Chemie

DOI

2026

Noninvasive Photoacoustic and Fluorescence Bimodality Imaging Differentiation of Vulnerable Atherosclerotic Plaques at Different Stages

Qiaochu Jiang, Penghao Zhen, Xinru Kong, Zihan Yuan, Yu Ma, Haidong Xu, Xiaoyang Liu, Fan Xing, Wenjun Zhan, Xianbao Sun, Gaolin Liang, Sisi Zhou

Journal of the American Chemical Society

DOI

2026

Membrane Protein‐Instructed Peptide Self‐Assembly for Cancer Therapy

Jiaying Zhang, Yanyan Zhou, Ruo‐Chen Guo, Junyan Du, Wenjun Zhan, Gaolin Liang

Advanced Functional Materials

DOI

2026

Peptide Self‐Assembly for Enhanced Cancer Therapy via Immunogenic Programmed Cell Death: Ferroptosis, Pyroptosis, Necroptosis, and Cuproptosis

Shasha Ning, Xinruo Xing, Yun‐Kai Chang, Mengmeng Mao, Hai‐Dong Xu, Yu Ma, Guowei Liang, Guowei Liang, Xianbao Sun, Gaolin Liang, Gaolin Liang

Macromolecular Rapid Communications

DOI

2026

Low-intensity pulsed ultrasound-mediated nose-to-brain co-delivery of β-blockers and aPD-L1 enhances glioblastoma immunotherapy

Lei Dong, Zhengcheng Yun, Lin Gao, Yue Li, Ying Zhou, Yini Zhu, Meng Li, Leqian Ying, Xuhong Yang, Jiangtao Yue, Xueqing Yong, Wanqing Cheng, Jia Miao, Nuo Xu, Xinyu Zhang, Hui Yang, Tingting Liu, Gaolin Liang, Shenghong Ju, Haijun Zhang, Jinbing Xie

Nature Communications

DOI

2026

Activatable NIR-II photoacoustic probes for cancer imaging and imaging-guided therapy

Runqun Tang, Ziyi Zhang, Shurong Shen, Gaolin Liang

Bioactive Materials

DOI

2026

A 19 F MRI/NIR‐FL Nanoprobe for “Turn‐On” Imaging of β‐Secretase (BACE1) Activity in Alzheimer's Disease

Lingling Xu, Qiaochu Jiang, Yuanyuan Jin, Tianyu Lin, Ruijie Cao, Haidong Xu, Xiaoyang Liu, Zhanjun Yang, Wenjun Zhan, Gaolin Liang

Angewandte Chemie

DOI

2026

FGFR2-responsive self-assembled hydrogel releases its inhibitor to suppress the progression of endometriosis

Panmei Ma, Shen Wang, Xier Zhang, Nana Li, Lu Xu, An Huang, Wenjun Zhan, Guangfeng Zhao, Dan Liu, Jiawen Sun, Gaolin Liang, Qiao Weng

Journal of Controlled Release

DOI

2026

Localized and sustained release of Botulinum Toxin A from supramolecular peptide hydrogel for strabismus treatment

Wei Guo, Hui Zhu, Yuchen Yao, Dan Huang, Tiantian Zhou, Xiaoqi Zhu, Jiaying Zhang, Gaolin Liang, Wenjun Zhan, Hu Liu

Theranostics

DOI

2026

A Spatially Ordered Three-Input Logic Gate for Highly Specific and Sensitive Breast Tumor Imaging

Hongzhe Yan, Xiaoyang Liu, Wenjun Zhan, Yi Yang, Fan Xing, Xiaotong Cheng, Zihan Yuan, Caifeng Ding, Gaolin Liang

Analytical Chemistry

DOI

2026

Caged Ligand-Decorated Near-Infrared Photosensitizer with In Vivo Albumin-Hijacking Capacity for Tumor-Targeted Hypoxia-Tolerant Photoimmunotherapy of Cancer

Xiaofeng Wu, Fan Xing, Yang Yang, Xiaoyang Liu, Gyoungmi Kim, Qiaochu Jiang, Yan Xu, Jingjing Hu, Gaolin Liang, Juyoung Yoon

Journal of the American Chemical Society

DOI

2025

ROS-differentiated release of Apelin-13 from hydrogel comprehensively treats myocardial ischemia-reperfusion injury.

Peng-Hao Zhen, Qiao-Chu Jiang, Fuchao Yu, Xuan Xu, Qin Wei, Xiao-Yang Liu, Xian-Bao Sun, Gaolin Liang, Jia-Yi Tong

Journal of Controlled Release

DOI

2025

Acid and phosphatase-triggered release and trapping of a prodrug on cancer cell enhance its chemotherapy.

Liang-Xi Zhu, Zixiu Shen, Xiaoyang Liu, Run-Qun Tang, Zi-Yi Zhang, Furong Zhao, Jue Wang, Wen-Jun Zhan, Lei Zhou, Gaolin Liang, Rui Wang

Biomaterials

DOI

2025

ROS and Caspase-3 Dual-Activated Photoacoustic Probe for Enhanced Imaging of Myocardial Ischemia-Reperfusion Injury

Penghao Zhen, Xianbao Sun, Ya Hu, Fuchao Yu, Xuan Xu, Wei Dong Qin, Qiaochu Jiang, Xiaoyang Liu, Gaolin Liang, Jiayi Tong

Analytical Chemistry

DOI

2025

Apoptosis‐Amplified Intracellular Paclitaxel Nanoparticle Formation Enhances Microtubule Aggregation and PANoptosis

Xiaoyang Liu, Xianbao Sun, Yu Ma, Qiaochu Jiang, Yun Yin, Haidong Xu, Xiaotong Cheng, Yang Yang, Yinghuan Li, Hongzhe Yan, Xinping Zhang, Xinwang Yu, Wenjun Zhan, Fu‐Gen Wu, Jun Wu, Ying Zhuo, Gaolin Liang

Angewandte Chemie

DOI

2025

Enhancing Breast Cancer Immunotherapy by Suppressing Sympathetic Nervous System-Driven T-Cell Exhaustion and Promoting T-Cell Priming and Trafficking

Lin Gao, Zhiyuan Luo, Lei Dong, Chanchan Gao, Xinyu Zhang, Xueqing Yong, Hui Yang, Ying Fang Zhou, Yue Li, Tingting Liu, Gaolin Liang, Mohd Rekaz Muddassir, Yini Zhu, Jinbing Xie

ACS Nano

DOI

2025

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

Xueying Cheng, Shuangyu Liu, Yu Zhang, Yu Zhang, Kang Peng, Muge Qile, Chao Wu, Mengyun Dou, Liu Liu, Na Young Yang, Rui Liu, Guiyang Zhang, Liangping Ni, Gaolin Liang, Fang Yang, Ye Zhang, Ye Zhang, Shufang He

Advanced Science

DOI

2025

Assembly/disassembly-based targeting protein degradation systems for cancer therapy

Hongzhe Yan, Xiaoyang Liu, Ying Jun Xu, Gaolin Liang, Xiaofeng Wu

EngMedicine

DOI

2025

Bioorthogonal chemistry-triggered engineering on cell membrane for precise bioimaging in living organisms

Yu Ma, Guowei Liang, Guowei Liang, Jue Wang, Xianbao Sun, Wenjun Zhan, Gaolin Liang, Gaolin Liang

TrAC Trends in Analytical Chemistry

DOI

2025

Cell Membrane-Anchored Click Reaction Enhances Porphyrin Uptake for Highly Efficient Photodynamic Therapy of Breast Tumors

Yu Ma, Xiaoyang Liu, Qiaochu Jiang, Haidong Xu, Guowei Liang, Guowei Liang, Wenjun Zhan, Xianbao Sun, Gaolin Liang, Gaolin Liang

Journal of the American Chemical Society

DOI

2025

Dually quenched and targeting nanoprobe for sensitive and specific fluorescence imaging of tumor

Guowei Liang, Guowei Liang, Tiantian Xia, Jingyang Huang, Xianbao Sun, Xiaoyang Liu, Gaolin Liang, Gaolin Liang, Xiaotong Cheng

Biosensors and Bioelectronics

DOI

2025

Atg4B-Activated Near-Infrared Nanoprobe for Precise Imaging of Autophagy In Vivo

Xiaotong Cheng, Tiantian Xia, Guowei Liang, Guowei Liang, Haidong Xu, Xiaoyang Liu, Gaolin Liang, Gaolin Liang

Analytical Chemistry

DOI

2025

Caspase 8-activated bioluminescence probe for in vivo imaging of programmable cell death

Zihan Yuan, Qiaochu Jiang, Jingyang Huang, Xiaoyang Liu, Xiaotong Cheng, Yang Yang, Hongzhe Yan, Xianbao Sun, Gaolin Liang

Biosensors and Bioelectronics

DOI

2025

Molecular afterglow imaging for biomedical applications

Cheng Xu, Yan Zhang, Gaolin Liang, Kanyi Pu

Nature Materials

DOI

2025

Sustained release of dual p38 inhibitors via supramolecular hydrogels to enhance cardiac repair after MI/R injury

Di Wang, Di Wang, Aoxue Xu, Haitao Su, Youpei Zhang, Youpei Zhang, Lingling Jiang, Yaguang Wang, Gaolin Liang, Ye Zhang, Ye Zhang

Biomaterials

DOI

2025

Intracellular nanofiber formation triggers nuclear fragmentation to enhance chemotherapeutic effect of camptothecin

Xiaotong Cheng, Tiantian Xia, Wenjun Zhan, Jiaoming Jiang, Xiaoyang Liu, Haidong Xu, Fu‐Gen Wu, Gaolin Liang

Cell Biomaterials

DOI

2025

Timed photothermal therapy combining fluorescence-on chemotherapy maximizes tumor treatment

Runqun Tang, Ziyi Zhang, Xiaoyang Liu, Haidong Xu, Liangxi Zhu, Xueqi Bai, Yinxing Miao, Wenjun Zhan, Zhonghua Shi, Gaolin Liang

Bioactive Materials

DOI

2025

A Caspase-3-Activatable Near-Infrared AIEgen for Tumor Apoptosis Imaging In Vivo

Lingling Xu, Yuanyuan Jin, Zhanjun Yang, Wenjun Zhan, Gaolin Liang, Shurong Shen

Chemical & Biomedical Imaging

DOI

2025

Displaying In Vivo “Assembly–Disassembly” Cascade with “Off–On–Off” Magnetic Resonance Imaging Signals in Tumor

Hai-Dong Xu, Xianbao Sun, Zheng Huang, Xiaotong Cheng, Xiancheng Fu, Jiayu Li, Ziwen Wei, Junchao Qian, Gaolin Liang

Journal of the American Chemical Society

DOI

2025

In situ peptide assembly for cell membrane rewiring in tumor therapy

Yu Ma, Qiaochu Jiang, Xiaoyang Liu, Xianbao Sun, Gaolin Liang

Journal of Controlled Release

DOI

2025

Coumarin Excimer Nanotube for Long-Time Lysosome Tracking

Yang Yang, Xiaoyang Liu, Ying Xu, Xing He Fan, Zihan Yuan, Yuxuan Chen, Xiaofeng Wu, Cailian Wang, Gaolin Liang

Nano Letters

DOI

2025

Dual-Locked Enzyme-Activatable Fluorescence Probes for Precise Bioimaging

Yang Liu, Yuchen Yao, Junhui Sha, Gaolin Liang, Xianbao Sun

ACS Biomaterials Science & Engineering

DOI

2025

Activatable peptide–AIEgen conjugates for cancer imaging

Sisi Zhou, Xianbao Sun, Gaolin Liang

Chemical Science

DOI

2024

高效稀土上转换纳米晶体合成

王睿，梁高林

《东南大学学报(自然科学版)》

2024

Inspired by nature: Bioluminescent systems for bioimaging applications.

Zi-Han Yuan, Qiao-Chu Jiang, Gaolin Liang

Talanta: The International Journal of Pure and Applied Analytical Chemistry

DOI

2024

A dual-locked cyclopeptide–siRNA conjugate for tumor-specific gene silencing

Chen Li, Shuaishuai Sun, Hao Kong, Xiangqian Xie, Gaolin Liang, Yan Zhang, Huan Wang, Jin-Bo Li

RSC Chemical Biology

DOI

2024

Pyruvate Kinase M2‐Responsive Release of Paclitaxel and Indoleamine 2,3‐Dioxygenase Inhibitor for Immuno‐Chemotherapy of Nonsmall Cell Lung Cancer

Haisi Wu, Xianbao Sun, Kaiming Li, Jinyu Li, Hui Jiang, Dan Yan, Lin Ya, Yan Ding, Yawen Lu, Xiaole Zhu, Xufeng Chen, Xiaolin Li, Gaolin Liang, Huae Xu

Advanced Science

DOI

2024

Spatially Quantitative Imaging of Enzyme Activity in a Living Cell

Rui Wang, Lei Zhou, Yueyan Yang, Furong Zhao, Xianbao Sun, Xiaoyang Liu, Zhen Zou, Gaolin Liang

Journal of the American Chemical Society

DOI

2024

“Turn-on” NIR-II fluorescence of a dually quenched probe for sensitive imaging of cathepsin B in vivo

Yu Deng, Kui Yan, Lingling Xu, Xiaoyang Liu, Furong Zhao, Shangfeng Wang, Fan Zhang, Gaolin Liang, Rui Wang

Chemical Communications

DOI

2024

Rational Design of an Activatable Near‐Infrared Fluorogenic Platform for In Vivo Orthotopic Tumor Imaging and Resection

Xiaofeng Wu, Deng‐Guang Yu, Rui Wang, Heejeong Kim, Gyoungmi Kim, Ying Xu, Kyung Tae Hong, Jun‐Seok Lee, Jingjing Hu, Gaolin Liang, Juyoung Yoon

Angewandte Chemie

DOI

2024

Fibroblast Growth Factor Receptor 1-Specific Dehydrogelation to Release Its Inhibitor for Enhanced Lung Tumor Therapy

Runqun Tang, Ziyi Zhang, Xiaoyang Liu, Liangxi Zhu, Yuting Xu, Renjie Chai, Wenjun Zhan, Shurong Shen, Gaolin Liang

ACS Nano

DOI

2024

Recent Advances in Self‐Assembling Peptide‐Based Nanomaterials for Enhanced Photodynamic Therapy

Ziyi Zhang, Runqun Tang, Xiaoyang Liu, Gaolin Liang, Xianbao Sun

Macromolecular Bioscience

DOI

2024

Tandem Targeting and Dual Aggregation of an AIEgen for Enhanced Near-Infrared Fluorescence Imaging of Tumors

Yu Deng, Lingling Xu, Xiaoyang Liu, Qiaochu Jiang, Xianbao Sun, Wenjun Zhan, Gaolin Liang

Journal of the American Chemical Society

DOI

2024

Activatable Fluorescence and Bio/Chemiluminescence Probes for Aminopeptidases: From Design to Biomedical Applications

Xiaofeng Wu, Yu Deng, Ying Xu, Heemin Kang, Jingjing Hu, Juyoung Yoon, Gaolin Liang

Advanced Materials

DOI

2024

Phe–Phe-Based Macroscopic Supramolecular Hydrogel Construction Strategies and Biomedical Applications

Xiaoyang Liu, Qiaochu Jiang, Yun Yin, Gaolin Liang

Chem & Bio Engineering

DOI

2024

Click reaction-induced in situ nanoparticle aggregation for cancer imaging and treatment

Yun Yin, Xiaoyang Liu, Xuemei Li, Gaolin Liang

EngMedicine

DOI

2024

In Situ Nanofiber Formation Blocks AXL and GAS6 Binding to Suppress Ovarian Cancer Development

Han Yin, Yue Hua, Songwei Feng, Yi Xu, Yue Ding, Sicong Liu, Dongsheng Chen, Furong Du, Gaolin Liang, Wenjun Zhan, Yang Shen

Advanced Materials

DOI

2024

β-Galactosidase-activated near-infrared AIEgen for ovarian cancer imaging in vivo

Lingling Xu, Hang Gao, Yu Deng, Xiaoyang Liu, Wenjun Zhan, Xianbao Sun, Jing‐Juan Xu, Gaolin Liang

Biosensors and Bioelectronics

DOI

2024

Three‐in‐One Peptide Prodrug with Targeting, Assembly and Release Properties for Overcoming Bacterium‐Induced Drug Resistance and Potentiating Anti‐Cancer Immune Response

Ge Gao, Yao‐Wen Jiang, Jiaxuan Chen, Xiaodi Xu, Xianbao Sun, Haidong Xu, Gaolin Liang, Xiaoyang Liu, Wenjun Zhan, Meng Wang, Yixin Xu, Junnian Zheng, Gang Wang

Advanced Materials

DOI

2024

Near-infrared AIEgens for sulfatase imaging in breast cancer in vivo

Lingling Xu, Yu Deng, Hang Gao, Yuchen Yao, Xiaoyang Liu, Wenjun Zhan, Gaolin Liang, Xianbao Sun

Nanoscale

DOI

2024

In situ peptide assemblies for bacterial infection imaging and treatment

Yanyan Zhou, Lingling Xu, Xianbao Sun, Wenjun Zhan, Gaolin Liang

Nanoscale

DOI

2023

Enzymatic self-assembly/disassembly turns “ON”/“OFF” the mimetic hydrolytic activity of histidine nanofibers

Xianbao Sun, Manli Wang, Xiaoyang Liu, Wenjun Zhan, Guangqiong Xu, Qiaochu Jiang, Haidong Xu, Fuqiang Wang, Gaolin Liang

Science China Chemistry

DOI

2023

A MOF-based nanobomb for tumor microvascular occlusion and combined tumor starvation therapy and chemotherapy

Xiaoyang Liu, Ya‐Xuan Zhu, Hao‐Ran Jia, Xinping Zhang, Ge Gao, Ke‐Fei Xu, Xin‐Wang Yu, Shihao Wang, Zixi Wang, Penghao Zhen, Gaolin Liang, Fu‐Gen Wu

Materials Today Nano

DOI

2023

Enzyme-Instructed CBT-Cys-like Click Cyclization Reactions for Bioimaging

Yang Yang, Xiaoyang Liu, Xiaofeng Wu, Gaolin Liang

Chemical & Biomedical Imaging

DOI

2023

Dual Aggregations of a Near-Infrared Aggregation-Induced Emission Luminogen for Enhanced Imaging of Alzheimer’s Disease

Lingling Xu, Hang Gao, Wenjun Zhan, Yu Deng, Xiaoyang Liu, Qiaochu Jiang, Xianbao Sun, Jing‐Juan Xu, Gaolin Liang

Journal of the American Chemical Society

DOI

2023

Intracellular Nitroreductase‐Triggered “On” and “Enhanced” Photoacoustic Signals for Sensitive Imaging of Tumor Hypoxia

Xianbao Sun, Lingling Xu, Haidong Xu, Limin Xie, Rui Wang, Zhimou Yang, Wenjun Zhan, Shurong Shen, Gaolin Liang

Advanced Healthcare Materials

DOI

2023

Enzyme‐Instructed Host‐Guest Assembly/Disassembly for Biomedical Applications

Hongzhe Yan, Xiaoyang Liu, Caifeng Ding, Gaolin Liang

ChemBioChem

DOI

2023

Atg4B and Cathepsin B-Triggered in Situ Luciferin Formation for Precise Cancer Autophagy Bioluminescence Imaging

Xiaotong Cheng, Tiantian Xia, Xianbao Sun, Guowei Liang, Guowei Liang, Xiaoyang Liu, Gaolin Liang, Gaolin Liang

ACS Central Science

DOI

2023

Aurora Kinase B‐Instruct Release of AZD1152‐HQPA from Hydrogel to Enhance Cervical Cancer Suppression

Guangqiong Xu, Qiao Weng, Lei Zhang, Yaye Song, Wenjun Zhan, Yuan Yin, Gaolin Liang, Fuqiang Wang

Advanced Functional Materials

DOI

2023

Activatable small molecular luminescence probes for autofluorescence-free bioimaging

Xianbao Sun, Lingling Xu, Xiaoyang Liu, Haidong Xu, Wenjun Zhan, Gaolin Liang

TrAC Trends in Analytical Chemistry

DOI

2023

Enhanced Photoacoustic Imaging of Urokinase-Type Plasminogen Activator Activity in Tumors

Xinyi Hu, Xianbao Sun, Xiaoyang Liu, Haidong Xu, Liang Yang, Songqin Liu, Rui Wang, Gaolin Liang

Analytical Chemistry

DOI

2023

β-Glucuronidase-Activated Bioluminescence Probe for In Vivo Tumor Imaging

Liang Yang, Xianbao Sun, Lingling Xu, Xiaotong Cheng, Xiaoyang Liu, Yu Deng, Xinyi Hu, Gaolin Liang

Analytical Chemistry

DOI

2023

Sustained Release of Neuroprotective Drugs Curcumin and Edaravone from Supramolecular Hydrogel for Ischemic Stroke Treatment

Yanpeng Jia, Yi Zhang, Wenjun Zhan, Yu Wang, Xianbao Sun, Yuan Zhang, Xiaoyang Liu, Bing Han, Ying Bai, Ling Shen, Gaolin Liang, Honghong Yao

Advanced Functional Materials

DOI

2023

Morphological Transformation of Self‐Assembled Peptide Nanostructures for Bioimaging Applications

Ying Xu, Qiaochu Jiang, Xianbao Sun, Gaolin Liang

Analysis & Sensing

DOI

2023

Assembly drives regioselective azide-alkyne cycloaddition reaction

Qiaochu Jiang, Wenjun Zhan, Xiaoyang Liu, Lin Ling Bai, Manli Wang, Ying Xu, Gaolin Liang

Nature Communications

DOI

2023

Caspase-3-Triggered Intracellular Gadolinium Nanoparticle Formation for T1-Weighted Magnetic Resonance Imaging of Apoptosis In Vivo

Haidong Xu, Xiaotong Cheng, Xianbao Sun, Peiyao Chen, Wenjun Zhan, Xiaoyang Liu, Xinliang Wang, Bing Hu, Gaolin Liang

Nano Letters

DOI

2023

Tandem Guest‐Host‐Receptor Recognitions Precisely Guide Ciprofloxacin to Eliminate Intracellular Staphylococcus aureus

Wenjun Zhan, Lingling Xu, Zhiyu Liu, Xiaoyang Liu, Ge Gao, Tiantian Xia, Xiaotong Cheng, Xianbao Sun, Fu‐Gen Wu, Qian Yu, Gaolin Liang

Angewandte Chemie

DOI

2023

A Chemiluminescent Probe for Imaging Peroxynitrite in Inflammatory Cells and Tissues

Yu Deng, Xiang Shi, Xinyi Hu, Lingling Xu, Xiaoyang Liu, Ge Gao, Rui Wang, Gaolin Liang

Analytical Chemistry

DOI

2023

Intracellular Construction of Cathepsin B‐Guided Gadolinium Nanoparticles for Enhanced T2‐Weighted MR Tumor Imaging

Mengxing Wei, Lulu Wang, Yanfang Wang, Tong Zhang, Chenchen Wang, Chengfan Wu, Changlin Tian, Gaolin Liang, Yue Yuan

Small

DOI

2023

Apoptosis-Amplified Assembly of Porphyrin Nanofiber Enhances Photodynamic Therapy of Oral Tumor

Xiaoyang Liu, Wenjun Zhan, Ge Gao, Qiaochu Jiang, Xinping Zhang, Hongbo Zhang, Xianbao Sun, Wei Han, Fu‐Gen Wu, Gaolin Liang

Journal of the American Chemical Society

DOI

2023

CBT‐Cys click reaction for optical bioimaging in vivo

Xinyi Hu, Runqun Tang, Lin Ling Bai, Songqin Liu, Gaolin Liang, Xianbao Sun

Open Research (University of Surrey)

DOI

2023

Facile Label-Free Three-Input Molecular Keypad Lock

Xianbao Sun, Tiantian Xia, Lingling Xu, Wenjun Zhan, Gaolin Liang

Analytical Chemistry

DOI

2023

Enzymatic Self‐Assembly of Adamantane‐Peptide Conjugate for Combating Staphylococcus aureus Infection

Wenjun Zhan, Ge Gao, Zhiyu Liu, Xiaoyang Liu, Lingling Xu, Manli Wang, Haidong Xu, Runqun Tang, Jing-Yuan Cao, Xianbao Sun, Gaolin Liang

Advanced Healthcare Materials

DOI

2023

Bisphosphonate-Modified Functional Supramolecular Hydrogel Promotes Periodontal Bone Regeneration by Osteoclast Inhibition

Chenglong Hu, Mei Zhang, Jin Wu, Xing Cao, Luxian Chen, Jiayin Yan, Gaolin Liang, Jiali Tan

ACS Applied Materials & Interfaces

DOI

2023

Weak acid-initiated slow release of Dexamethasone from hydrogel to treat orbital inflammation

Jinjing Li, Aichi Zhang, Andi Zhao, Zhaoxia Chen, Gaolin Liang, Hu Liu, Chengfan Wu

Theranostics

DOI

2022

自组装多肽探针在磁共振成像中的应用

徐海东，王睿，梁高林

《高等学校化学学报》

2022

Highly lipophilic coumarin fluorophore with excimer-monomer transition property for lipid droplet imaging

Xiang Shi, Ge Gao, Xiaoyang Liu, Lingling Xu, Yu Deng, Rui Wang, Gaolin Liang

Chinese Chemical Letters

DOI

2022

ROS Turn Nanoparticle Fluorescence on for Imaging Staphylococcus aureus Infection In Vivo

Lingling Xu, Wenjun Zhan, Yu Deng, Xiaoyang Liu, Ge Gao, Xianbao Sun, Gaolin Liang

Advanced Healthcare Materials

DOI

2022

Realization of firefly bioluminescence cycle in vitro and in cells

Zhen Zheng, Tiantian Xia, Tao Wang, Deying Jia, Ziye Wu, Jun Jiang, Gaolin Liang

Biosensors and Bioelectronics

DOI

2022

Granzyme B Turns Nanoparticle Fluorescence “On” for Imaging Cytotoxic T Lymphocyte Activity in Vivo

Lingling Xu, Nanhui Liu, Wenjun Zhan, Yu Deng, Zhaoxia Chen, Xiaoyang Liu, Ge Gao, Qian Chen, Zhuang Liu, Gaolin Liang

ACS Nano

DOI

2022

Enzymatic Nanosphere‐to‐Nanofiber Transition and Autophagy Inducer Release Promote Tumor Chemotherapy

Xiaotong Cheng, Tiantian Xia, Wenjun Zhan, Haidong Xu, Jiaoming Jiang, Xiaoyang Liu, Xianbao Sun, Fu‐Gen Wu, Gaolin Liang

Advanced Healthcare Materials

DOI

2022

Photoswitchable Nanofiber–Nanoparticle Transformation in a Cosolvent Gel–Sol System

Tiantian Xia, Xiaotong Cheng, Xianbao Sun, Gaolin Liang

ACS Materials Letters

DOI

2022

FAP-α-Instructed Coumarin Excimer Formation for High Contrast Fluorescence Imaging of Tumor

Ge Gao, Xianbao Sun, Xiaoyang Liu, Runqun Tang, Manli Wang, Wenjun Zhan, Junnian Zheng, Gaolin Liang

Nano Letters

DOI

2022

Trident Molecule with Nanobrush–Nanoparticle–Nanofiber Transition Property Spatially Suppresses Tumor Metastasis

Ge Gao, Yao‐Wen Jiang, Wenjun Zhan, Xiaoyang Liu, Runqun Tang, Xianbao Sun, Yu Deng, Lingling Xu, Gaolin Liang

Journal of the American Chemical Society

DOI

2022

Salt‐Inducible Kinase 2‐Triggered Release of Its Inhibitor from Hydrogel to Suppress Ovarian Cancer Metastasis

Yue Hua, Han Yin, Xiaoyang Liu, Jinbing Xie, Wenjun Zhan, Gaolin Liang, Yang Shen

Advanced Science

DOI

2022

Polymeric carbon nitride-based materials: Rising stars in bioimaging

Sicheng Liang, Zhuang Wang, Zhixin Zhou, Gaolin Liang, Yuanjian Zhang

Biosensors and Bioelectronics

DOI

2022

An aminopeptidase N-activatable chemiluminescence probe for image-guided surgery and metastasis tracking of tumor

Xiang Shi, Yu Deng, Xiaoyang Liu, Ge Gao, Rui Wang, Gaolin Liang

Biosensors and Bioelectronics

DOI

2022

“Hepatitis virus indicator”----the simultaneous detection of hepatitis B and hepatitis C viruses based on the automatic particle enumeration

Ru Cheng, Zhu Fu, Min Jian Huang, Qiang Zhang, Hui Hong Yan, Xiao Hui Zhao, Fu Kang Luo, Chun Mei Li, Hui Liu, Gaolin Liang, Cheng Zhi Huang, Jian Wang

Biosensors and Bioelectronics

DOI

2022

Acidity-Activated Charge Conversion of 177 Lu-Labeled Nanoagent for the Enhanced Photodynamic Radionuclide Therapy of Cancer

Yuan Zhang, Guanglin Wang, Qing Li, Yue Jiang, Wan Chen, Min Zhao, Gaolin Liang, Qingqing Miao

ACS Applied Materials & Interfaces

DOI

2022

V1-Cal hydrogelation enhances its effects on ventricular remodeling reduction and cardiac function improvement post myocardial infarction

Bin Wang, Chengfan Wu, Shufang He, Yaguang Wang, Di Wang, Hui Tao, Chenchen Wang, Xiaoxi Pang, Fei Li, Yue Yuan, Eric Richard Gross, Gaolin Liang, Ye Zhang

Chemical Engineering Journal

DOI

2022

MMP 9-instructed assembly of bFGF nanofibers in ischemic myocardium to promote heart repair

Yaguang Wang, Di Wang, Chao Wu, Bin Wang, Shufang He, Hua Wang, Gaolin Liang, Ye Zhang

Theranostics

DOI

2021

An Acidity-Initiated Self-Assembly/Disassembly Nanoprobe to Switch on Fluorescence for Tumor-Targeted Near-Infrared Imaging

Rui Luo, Chunqing Ou, Xinchao Li, Yanfang Wang, Wei Du, Gaolin Liang, Changyang Gong

Nano Letters

DOI

2021

Cathespin B‐Initiated Cypate Nanoparticle Formation for Tumor Photoacoustic Imaging

Chenchen Wang, Wei Du, Chenfan Wu, Shan Dan, Miao Sun, Tong Zhang, Bin Wang, Yue Yuan, Gaolin Liang

Angewandte Chemie

DOI

2021

Simultaneous enhancement of T1 and T2 magnetic resonance imaging of liver tumor at respective low and high magnetic fields

Huan Li, Zijuan Hai, Liwei Zou, Lele Zhang, Lulu Wang, Longsheng Wang, Gaolin Liang

Theranostics

DOI

2021

Lysosome‐Targeted and Fluorescence‐Turned “On” Cytotoxicity Induced by Alkaline Phosphatase‐Triggered Self‐Assembly

Chengfan Wu, Chenchen Wang, Tong Zhang, Ge Gao, Mengxing Wei, Yinglu Chen, Xiaoyan Li, Fuqiang Wang, Gaolin Liang

Advanced Healthcare Materials

DOI

2021

Activity‐Based Luciferase‐Luciferin Bioluminescence System for Bioimaging Applications

Tiantian Xia, Xiaotong Cheng, Wenjun Zhan, Gaolin Liang

Analysis & Sensing

DOI

2021

Bioluminescence Imaging of Urokinase-Type Plasminogen Activator Activity in Vitro and in Tumors

Yinglu Chen, Chengfan Wu, Chenchen Wang, Tong Zhang, Yue Hua, Yang Shen, Gaolin Liang

Analytical Chemistry

DOI

2021

In situ Activatable Peptide-based Nanoprobes for Tumor Imaging

Zhiyu Liu, Gaolin Liang, Wenjun Zhan

Chemical Research in Chinese Universities

DOI

2021

Intracellular Nanoparticle Formation and Hydroxychloroquine Release for Autophagy‐Inhibited Mild‐Temperature Photothermal Therapy for Tumors

Ge Gao, Xianbao Sun, Xiaoyang Liu, Yao‐Wen Jiang, Runqun Tang, Yuxin Guo, Fu‐Gen Wu, Gaolin Liang

Advanced Functional Materials

DOI

2021

Glutathione-Depleting Nanomedicines for Synergistic Cancer Therapy

Xiaotong Cheng, Haidong Xu, Huan-Huan Ran, Gaolin Liang, Fu‐Gen Wu

ACS Nano

DOI

2021

Intracellular Synthesis of Hybrid Gallium-68 Nanoparticle Enhances MicroPET Tumor Imaging

Peiyao Chen, Hongyong Wang, Hao Wu, Pei Zou, Chenchen Wang, Xiaoyang Liu, Yue Pan, Yaling Liu, Gaolin Liang

Analytical Chemistry

DOI

2021

Nanoagent‐Promoted Mild‐Temperature Photothermal Therapy for Cancer Treatment

Ge Gao, Xianbao Sun, Gaolin Liang

Advanced Functional Materials

DOI

2021

Using Fluorescence On/Off to Trace Tandem Nanofiber Assembly/Disassembly in Living Cells

Miaomiao Zhang, Chenchen Wang, Chen Yang, Haisi Wu, Huae Xu, Gaolin Liang

Analytical Chemistry

DOI

2021

Dual Gate‐Controlled Therapeutics for Overcoming Bacterium‐Induced Drug Resistance and Potentiating Cancer Immunotherapy

Xiaodong Zhang, Xiaokai Chen, Yuxin Guo, Ge Gao, Dongdong Wang, Yinglong Wu, Jiawei Liu, Gaolin Liang, Yanli Zhao, Fu‐Gen Wu

Angewandte Chemie

DOI

2021

Size-Dependent Plasmonic Resonance Scattering Characteristics of Gold Nanorods for Highly Sensitive Detection of microRNA-27a

Hui Hong Yan, Qiang Zhang, Ru Cheng, Zhu Fu, Jia Jun Liu, Peng Fei Gao, Hong Yan Zou, Gaolin Liang, Cheng Zhi Huang, Jian Wang

ACS Applied Bio Materials

DOI

2021

Self-assembly of peptide nanofibers for imaging applications

Qiaochu Jiang, Xiaoyang Liu, Gaolin Liang, Xianbao Sun

Nanoscale

DOI

2020

A Golgi-Targeting and Dual-Color “Turn-On” Probe for Spatially Precise Imaging of Furin

Xiao Hu, Zijuan Hai, Chengfan Wu, Wenjun Zhan, Gaolin Liang

Analytical Chemistry

DOI

2020

Receptor tyrosine kinases-instructed release of its inhibitor from hydrogel to delay ovarian aging

Zhonghua Shi, Xiaoyan Li, Mengxing Wei, Peiyao Chen, Ting Zhang, Xiufeng Ling, Junqiang Zhang, Chun Ling Zhao, Fuqiang Wang, Gaolin Liang

Biomaterials

DOI

2020

A Bioluminescent Probe for Simultaneously Imaging Esterase and Histone Deacetylase Activity in a Tumor

Chenchen Wang, Wei Du, Tong Zhang, Gaolin Liang

Analytical Chemistry

DOI

2020

Directly observing intracellular nanoparticle formation with nanocomputed tomography

Miaomiao Zhang, Yong Guan, Zheng Dang, Pinggen Zhang, Zhen Zheng, Liang Chen, Wen Kuang, Chenchen Wang, Gaolin Liang

Science Advances

DOI

2020

Furin‐Instructed Intracellular Gold Nanoparticle Aggregation for Tumor Photothermal Therapy

Jihua Chen, Yinchu Ma, Wei Du, Tianyue Dai, Yanfang Wang, Wei Juan Jiang, Yifei Wan, Yucai Wang, Gaolin Liang, Guangfeng Wang

Advanced Functional Materials

DOI

2020

Intracellular Self‐Assembly of Peptide Conjugates for Tumor Imaging and Therapy

Yu Deng, Wenjun Zhan, Gaolin Liang

Advanced Healthcare Materials

DOI

2020

High-Resolution Vertical Polarization Excited Dark-Field Microscopic Imaging of Anisotropic Gold Nanorods for the Sensitive Detection and Spatial Imaging of Intracellular microRNA-21

Jia Jun Liu, Hui Hong Yan, Qiang Zhang, Peng Fei Gao, Chun Mei Li, Gaolin Liang, Cheng Zhi Huang, Jian Wang

Analytical Chemistry

DOI

2020

Peptide-based supramolecular hydrogels for bioimaging applications

Xiaoyang Liu, Xianbao Sun, Gaolin Liang

Biomaterials Science

DOI

2020

A Self-Evaluating Photothermal Therapeutic Nanoparticle

Yanfang Wang, Wei Du, Tong Zhang, Yu Zhu, Yanhan Ni, Chenchen Wang, Fatima Maria Sierra Raya, Liwei Zou, Longsheng Wang, Gaolin Liang

ACS Nano

DOI

2020

Enzyme‐Mediated Tumor Starvation and Phototherapy Enhance Mild‐Temperature Photothermal Therapy

Ge Gao, Yao‐Wen Jiang, Yuxin Guo, Hao‐Ran Jia, Xiaotong Cheng, Yu Deng, Xin‐Wang Yu, Ya‐Xuan Zhu, Haoyue Guo, Wei Sun, Xiaoyang Liu, Jing Zhao, Shihe Yang, Zhi‐Wu Yu, Fatima Maria Sierra Raya, Gaolin Liang, Fu‐Gen Wu

Advanced Functional Materials

DOI

2020

Covalently Conjugated Hydrogelators for Imaging and Therapeutic Applications

Xiaotong Cheng, Jiaoming Jiang, Gaolin Liang

Bioconjugate Chemistry

DOI

2019

Increasing Photothermal Efficacy by Simultaneous Intra‐ and Intermolecular Fluorescence Quenching

Wei Du, Yuanyuan Chong, Xiaomu Hu, Yanfang Wang, Yu Zhu, Jihua Chen, Xiaoxia Li, Qun Zhang, Guangfeng Wang, Jun Jiang, Gaolin Liang

Advanced Functional Materials

DOI

2019

Furin-Guided Intracellular 68Ga Nanoparticle Formation Enhancing Tumor MicroPET Imaging

Hongyong Wang, Peiyao Chen, Hao Wu, Pei Zou, Jun Wu, Yaling Liu, Gaolin Liang

Analytical Chemistry

DOI

2019

Furin‐Controlled Fe3O4 Nanoparticle Aggregation and 19F Signal “Turn‐On” for Precise MR Imaging of Tumors

Zhanling Ding, Hongbin Sun, Shuchao Ge, Yuan Cai, Yue Yuan, Zijuan Hai, Tongxiang Tao, Jinming Hu, Bing Hu, Junfeng Wang, Gaolin Liang

Advanced Functional Materials

DOI

2019

Facile syntheses of conjugated polymers for photothermal tumour therapy

Peiyao Chen, Yinchu Ma, Zhen Zheng, Chengfan Wu, Yucai Wang, Gaolin Liang

Nature Communications

DOI

2018

Applications of CBT-Cys click reaction: past, present, and future

Miaomiao Zhang, Gaolin Liang

Science China Chemistry

2018

Alkaline Phosphatase-Triggered Self-Assembly of Near-Infrared Nanoparticles for the Enhanced Photoacoustic Imaging of Tumors

Chengfan Wu, Rui Zhang, Wei Du, Liang Cheng, Gaolin Liang

Nano Letters

DOI

2017

紫杉醇水凝胶成胶因子延缓微管蛋白聚集(英文)

梅斌，梁高林

Chinese Journal of Chemical Physics

2017

利用含RGD的多肽增进细胞摄取用于细胞中弗林酶活性的检测

王雨薇，梁高林

Journal of University of Science and Technology of China

2016

天青蛋白突变体的表达及其与顺铂前药的作用

刘晓璇，王震，梁高林，赵林泓

《中国科学技术大学学报》

2016

正交点击反应对应用于标记细胞器

罗宇峰，梁高林

《中国科学技术大学学报》

2015

自组装纳米荧光探针用于caspase-3的检测

韩晓三，梁高林

《中国科学技术大学学报》

2015

19F核磁共振探针用于体外和活细胞内弗林蛋白酶的活性检测

王丁俐，梁高林

《中国科学技术大学学报》

2005

植物雌激素kobophenol A 的体内代谢产物及其机理研究

梁高林

《复旦大学》

2005

大花红天素分离、合成及其含量分析

黄宏卿，程科军，梁高林，胡昌奇

《天然产物研究与开发》

2003

3,3,10,10-四甲基-4,9-二氮杂十二烷-2,11-二酮肟的合成

梁高林，虞燕华，陈志明

《中国医药工业杂志》

2002

亚甲基二膦酸的合成

梁高林，虞燕华，陈志明，蒋登高，罗世能

《中国现代应用药学》

2002

去势雌性大鼠骨质疏松症的药物干预疗效的评价

陶永辉，谭成，蔡刚明，张荣军，胡名扬，梁高林，张莲芬，俞惠新，蒋孟军，肖晔，金坚，王博诚

《中国骨质疏松杂志》

2002

双膦酸盐类药物的合成研究

梁高林

《郑州大学》

2001

依替菲宁的合成

梁高林，胡名扬，虞燕华

《中国现代应用药学》

2001

时间分辨荧光免疫分析中β-NTA及其增强液的制备

胡名扬，梁高林，虞燕华，黄飚，金坚

《中华核医学与分子影像杂志》

2001

药物干预去势雌性大鼠骨质疏松症发生效果的评价

张荣军，蔡刚明，谭成，陶永辉，胡名扬，梁高林，张莲芬，蒋孟军，俞惠新，赵燕，肖晔，王博诚，金坚

《中国骨质疏松杂志》

2000

骨显像剂99Tcm-BM的研制

虞燕华，杨洪，王博诚，冯英英，梁高林，杨敏，陈志明，汪洋，胡名扬

《中华核医学与分子影像杂志》

2000

肝ASGP受体显像剂99mTc-NGA的实验研究

张荣军，金坚，梁高林，万卫星，李文新，陶永辉，胡名扬

《中国核科技报告》

2000

肝ASGP受体功能显像剂的制备及显像研究

张荣军，梁高林，万卫星，蔡刚明，叶万忠，陶永辉，张莲芬，谭成，金坚

《核技术》

1999

帕米膦酸二钠的合成

梁高林，胡名扬，王博诚

《中国现代应用药学》

1998

奥昔膦酸盐的合成

胡名扬，梁高林，杨敏，虞燕华

《中国医药工业杂志》

1998

唾液酸糖蛋白的合成

梁高林，金坚，胡名扬，张荣军，虞燕华

《中国医药工业杂志》

1998

4-氨基-1-羟丁基-1,1-二膦酸单钠盐的合成与表征

胡名扬，王博诚，梁高林，杨敏

《化学试剂》

1998

S-N-[(1-乙基-2-吡咯烷基)甲基]-2-羟基-3-碘-6-甲氧基苯甲酰胺的合成

胡名扬，梁高林，潘尚仁

《化学试剂》

1997

肝半乳糖受体显像剂前体氰甲基硫苷的合成

梁高林，胡名扬，金坚

《中国医药工业杂志》

1997

多巴胺D2受体显像剂125I-IBZM的合成与标记

胡名扬，梁高林，潘尚仁

《核化学与放射化学》

精选作品

期刊论文

Fibroblast activation protein-α-triggered photoacoustic signal “on” for pancreatic tumor imaging

An OGP binding protein complex-mimicking peptide hydrogel for dental pulp regeneration

“Turn-On” Nanoprobe for Stage-Differential Imaging of Inflammatory Bowel Disease

Matrix Metalloproteinase-9-Activated Dually-Quenched Fluorescence Nanoprobe for Sensitive Imaging of Rheumatoid Arthritis

An Enterokinase-Activatable Bioluminescent Probe for In Vivo Tumor Imaging

In Situ Peptide Assembly for Cancer Therapy

Noninvasive Photoacoustic and Fluorescence Bimodality Imaging Differentiation of Vulnerable Atherosclerotic Plaques at Different Stages

Membrane Protein‐Instructed Peptide Self‐Assembly for Cancer Therapy

Peptide Self‐Assembly for Enhanced Cancer Therapy via Immunogenic Programmed Cell Death: Ferroptosis, Pyroptosis, Necroptosis, and Cuproptosis

Low-intensity pulsed ultrasound-mediated nose-to-brain co-delivery of β-blockers and aPD-L1 enhances glioblastoma immunotherapy

Activatable NIR-II photoacoustic probes for cancer imaging and imaging-guided therapy

A 19 F MRI/NIR‐FL Nanoprobe for “Turn‐On” Imaging of β‐Secretase (BACE1) Activity in Alzheimer's Disease

FGFR2-responsive self-assembled hydrogel releases its inhibitor to suppress the progression of endometriosis

Localized and sustained release of Botulinum Toxin A from supramolecular peptide hydrogel for strabismus treatment

A Spatially Ordered Three-Input Logic Gate for Highly Specific and Sensitive Breast Tumor Imaging

Caged Ligand-Decorated Near-Infrared Photosensitizer with In Vivo Albumin-Hijacking Capacity for Tumor-Targeted Hypoxia-Tolerant Photoimmunotherapy of Cancer

ROS-differentiated release of Apelin-13 from hydrogel comprehensively treats myocardial ischemia-reperfusion injury.

Acid and phosphatase-triggered release and trapping of a prodrug on cancer cell enhance its chemotherapy.

ROS and Caspase-3 Dual-Activated Photoacoustic Probe for Enhanced Imaging of Myocardial Ischemia-Reperfusion Injury

Apoptosis‐Amplified Intracellular Paclitaxel Nanoparticle Formation Enhances Microtubule Aggregation and PANoptosis

Enhancing Breast Cancer Immunotherapy by Suppressing Sympathetic Nervous System-Driven T-Cell Exhaustion and Promoting T-Cell Priming and Trafficking

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

Assembly/disassembly-based targeting protein degradation systems for cancer therapy

Bioorthogonal chemistry-triggered engineering on cell membrane for precise bioimaging in living organisms

Cell Membrane-Anchored Click Reaction Enhances Porphyrin Uptake for Highly Efficient Photodynamic Therapy of Breast Tumors

Dually quenched and targeting nanoprobe for sensitive and specific fluorescence imaging of tumor

Atg4B-Activated Near-Infrared Nanoprobe for Precise Imaging of Autophagy In Vivo

Caspase 8-activated bioluminescence probe for in vivo imaging of programmable cell death

Molecular afterglow imaging for biomedical applications

Sustained release of dual p38 inhibitors via supramolecular hydrogels to enhance cardiac repair after MI/R injury

Intracellular nanofiber formation triggers nuclear fragmentation to enhance chemotherapeutic effect of camptothecin

Timed photothermal therapy combining fluorescence-on chemotherapy maximizes tumor treatment

A Caspase-3-Activatable Near-Infrared AIEgen for Tumor Apoptosis Imaging In Vivo

Displaying In Vivo “Assembly–Disassembly” Cascade with “Off–On–Off” Magnetic Resonance Imaging Signals in Tumor

In situ peptide assembly for cell membrane rewiring in tumor therapy

Coumarin Excimer Nanotube for Long-Time Lysosome Tracking

Dual-Locked Enzyme-Activatable Fluorescence Probes for Precise Bioimaging

Activatable peptide–AIEgen conjugates for cancer imaging

高效稀土上转换纳米晶体合成

Inspired by nature: Bioluminescent systems for bioimaging applications.

A dual-locked cyclopeptide–siRNA conjugate for tumor-specific gene silencing

Pyruvate Kinase M2‐Responsive Release of Paclitaxel and Indoleamine 2,3‐Dioxygenase Inhibitor for Immuno‐Chemotherapy of Nonsmall Cell Lung Cancer

Spatially Quantitative Imaging of Enzyme Activity in a Living Cell

“Turn-on” NIR-II fluorescence of a dually quenched probe for sensitive imaging of cathepsin B in vivo

Rational Design of an Activatable Near‐Infrared Fluorogenic Platform for In Vivo Orthotopic Tumor Imaging and Resection

Fibroblast Growth Factor Receptor 1-Specific Dehydrogelation to Release Its Inhibitor for Enhanced Lung Tumor Therapy

Recent Advances in Self‐Assembling Peptide‐Based Nanomaterials for Enhanced Photodynamic Therapy

Tandem Targeting and Dual Aggregation of an AIEgen for Enhanced Near-Infrared Fluorescence Imaging of Tumors

Activatable Fluorescence and Bio/Chemiluminescence Probes for Aminopeptidases: From Design to Biomedical Applications

Phe–Phe-Based Macroscopic Supramolecular Hydrogel Construction Strategies and Biomedical Applications

Click reaction-induced in situ nanoparticle aggregation for cancer imaging and treatment

In Situ Nanofiber Formation Blocks AXL and GAS6 Binding to Suppress Ovarian Cancer Development

β-Galactosidase-activated near-infrared AIEgen for ovarian cancer imaging in vivo

Three‐in‐One Peptide Prodrug with Targeting, Assembly and Release Properties for Overcoming Bacterium‐Induced Drug Resistance and Potentiating Anti‐Cancer Immune Response

Near-infrared AIEgens for sulfatase imaging in breast cancer in vivo

In situ peptide assemblies for bacterial infection imaging and treatment

Enzymatic self-assembly/disassembly turns “ON”/“OFF” the mimetic hydrolytic activity of histidine nanofibers

A MOF-based nanobomb for tumor microvascular occlusion and combined tumor starvation therapy and chemotherapy

Enzyme-Instructed CBT-Cys-like Click Cyclization Reactions for Bioimaging

Dual Aggregations of a Near-Infrared Aggregation-Induced Emission Luminogen for Enhanced Imaging of Alzheimer’s Disease

Intracellular Nitroreductase‐Triggered “On” and “Enhanced” Photoacoustic Signals for Sensitive Imaging of Tumor Hypoxia

Enzyme‐Instructed Host‐Guest Assembly/Disassembly for Biomedical Applications

Atg4B and Cathepsin B-Triggered in Situ Luciferin Formation for Precise Cancer Autophagy Bioluminescence Imaging

Aurora Kinase B‐Instruct Release of AZD1152‐HQPA from Hydrogel to Enhance Cervical Cancer Suppression

Activatable small molecular luminescence probes for autofluorescence-free bioimaging

Enhanced Photoacoustic Imaging of Urokinase-Type Plasminogen Activator Activity in Tumors

β-Glucuronidase-Activated Bioluminescence Probe for In Vivo Tumor Imaging

Sustained Release of Neuroprotective Drugs Curcumin and Edaravone from Supramolecular Hydrogel for Ischemic Stroke Treatment

Morphological Transformation of Self‐Assembled Peptide Nanostructures for Bioimaging Applications

Assembly drives regioselective azide-alkyne cycloaddition reaction

Caspase-3-Triggered Intracellular Gadolinium Nanoparticle Formation for T1-Weighted Magnetic Resonance Imaging of Apoptosis In Vivo

Tandem Guest‐Host‐Receptor Recognitions Precisely Guide Ciprofloxacin to Eliminate Intracellular Staphylococcus aureus

A Chemiluminescent Probe for Imaging Peroxynitrite in Inflammatory Cells and Tissues

Intracellular Construction of Cathepsin B‐Guided Gadolinium Nanoparticles for Enhanced T2‐Weighted MR Tumor Imaging

Apoptosis-Amplified Assembly of Porphyrin Nanofiber Enhances Photodynamic Therapy of Oral Tumor

CBT‐Cys click reaction for optical bioimaging in vivo

Facile Label-Free Three-Input Molecular Keypad Lock

Enzymatic Self‐Assembly of Adamantane‐Peptide Conjugate for Combating Staphylococcus aureus Infection