徐宏伟｜青岛大学｜学者主页

2026

Ubiquitin-specific protease 11 promotes tubular cell senescence via inhibiting p53 ubiquitin degradation during renal fibrosis.

Xin Wang, Ming Ning, Heng-Min Wang, Jing-yao Li, Xin Xie, Hongyan Xie, Luxin Li, Xi-ang Sun, Li Lu, Yitao Zhang, Li Zhou, Chen Xu, Q. Shen, Li-Min Lu, Hongwei Xu

Cellular Signalling

DOI

2025

SHROOM3 Deficiency Aggravates Adriamycin-Induced Nephropathy Accompanied by Focal Adhesion Disassembly and Stress Fiber Disorganization

Linan Xu, Yingying Sun, Yangjing Tan, Xinyue Zhou, Tian-Chao Xiang, Ye Fang, Fei Li, Q. Shen, Hongwei Xu, Jia Rao

Cells

DOI

2024

GEN1 as a risk factor for human congenital anomalies of the kidney and urinary tract

Xuanjin Du, Chun-Yan Wang, Jia-Lu Liu, Minghui Yu, Hai-ming Ju, Shan-Shan Xue, Yaxin Li, Jiaojiao Liu, R. Dai, Jing Chen, Yi-Hui Zhai, Jia Rao, Xiang Wang, Yu-Bo Sun, Lei Sun, Xiao-Hui Wu, Hongwei Xu, Q. Shen

Human Genomics

DOI

2024

USP11 promotes renal tubular cell pyroptosis and fibrosis in UUO mice via inhibiting KLF4 ubiquitin degradation

Xin Wang, Xin Xie, Jia-yun Ni, Jing-yao Li, Xi-ang Sun, Hong-yan Xie, Ning-Hao Yang, Heng-jiang Guo, Li Lu, Ming Ning, Li Zhou, Jun Liu, Chen Xu, Wei Zhang, Yi Wen, Q. Shen, Hongwei Xu, Li-Min Lu

Acta Pharmacologica Sinica

DOI

2023

Minnelide combined with anti-ANGPTL3-FLD monoclonal antibody completely protects mice with adriamycin nephropathy by promoting autophagy and inhibiting apoptosis

Baowei Ji, Jun-Chao Liu, Ye Yin, Hongwei Xu, Q. Shen, Jian Yu

Cell Death and Disease

DOI

2023

Genetic Spectrum of Congenital Anomalies of the Kidney and Urinary Tract in Chinese Newborn Genome Project

Zhe-Lan Huang, Q. Shen, Bing-Bing Wu, Hui-Jun Wang, Xin-Ran Dong, Yu-Lan Lu, Guo-Qiang Cheng, Lai-Shuan Wang, Wei Lu, Li-Ping Chen, W. Kang, Long Li, Xin-Nian Pan, Q. Wei, D. Zhuang, Dong-shen Chen, Zhaoqing Yin, Ling Yang, Q. Ni, Ren-Chao Liu, Gang Li, Ping Zhang, Yanyan Qian, Xiaomin Peng, Yao Wang, Yun Cao, Hongwei Xu, Li-Yuan Hu, Lin Yang, Wenhao Zhou

Kidney International Reports

DOI

2023

Overexpression of long noncoding RNA 4933425B07Rik leads to renal hypoplasia by inactivating Wnt/β-catenin signaling pathway

Shan-Shan Xue, Xuanjin Du, Minghui Yu, Hai-ming Ju, L. Tan, Yaxin Li, Jia-Lu Liu, Chun-Yan Wang, Xiao-Hui Wu, Hongwei Xu, Q. Shen

Frontiers in Cell and Developmental Biology

DOI

2022

Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage

Qian-Ying Lv, Xinli Han, Jiajia Ni, Qia-Yi Ma, R. Dai, Jiaojiao Liu, Jia-Lu Liu, Yi-Hui Zhai, Q. Shen, Li Sun, Hai-mei Liu, Jia Rao, Hongwei Xu

Cell Death and Disease

DOI

2022

N6-Methyladenosine Methylomic Landscape of Ureteral Deficiency in Reflux Uropathy and Obstructive Uropathy

Hua Shi, Tianchao Xiang, Jiayan Feng, Xue Yang, Yaqi Li, Ye Fang, Linan Xu, Qi-Wei Qi, Jian Shen, Liang-Feng Tang, Q. Shen, Xiang Wang, Hongwei Xu, Jia Rao

Frontiers in Medicine

DOI

2022

Protective role of endorepellin in renal developmental programming

Xiaoshan Tang, Manqing Sun, Q. Shen, Jia Rao, Xue Yang, Ye Fang, Tianchao Xiang, Shan-Shan Xue, Lei Sun, Hongwei Xu

Frontiers in Cell and Developmental Biology

DOI

2020

Human and mouse studies establish TBX6 in Mendelian CAKUT and as a potential driver of kidney defects associated with the 16p11.2 microdeletion syndrome

Nan Yang, N. Wu, Shuangshuang Dong, Ling Zhang, Yan-Xue Zhao, Wei-Sheng Chen, R. Du, Chengcheng Song, Xiaojun Ren, Jia-Qi Liu, D. Pehlivan, Zhen-Lei Liu, Rao Jia, Chunyan Wang, Sen Zhao, Amy M. Breman, Huadan Xue, Hao Sun, Jian-Xiong Shen, Shu-Yang Zhang, J. Posey, Hongwei Xu, Li Jin, Jian-Guo Zhang, Peng-Fei Liu, S. Sanna-Cherchi, G. Qiu, Zhi-Hong Wu, J. Lupski, Feng Zhang

Kidney International

DOI

2020

Biophysical and Structural Characterization of Non-Canonical DNA Structures

Linda Yingqi Lin, Liliya A. Y atsunyk, L. Yatsunyk, Jessica Chen, Hyun Kyung Lee, Hongwei Xu, Flaminia Marucci, Y. Kuang

2010

KDR siRNA对乳癌细胞凋亡和NES1与RUNX3基因甲基化影响

许秀娥，徐宏伟，葛银林，张金玉，冯翠萍

《青岛大学学报(医学版)》

2010

Expression of Angiopoietin-Like 3 Associated with Puromycin-Induced Podocyte Damage

Jia Rao, Hongwei Xu, Li Sun, Hai-Chun Yang, Chuanming Hao

Nephron Experimental Nephrology

DOI

2009

KDR靶向RNA干扰对MCF-7细胞凋亡的影响(英文)

许秀娥，徐宏伟，李泉，葛银林

《现代生物医学进展》

2006

维生素E对大鼠心肌线粒体ATP酶和抗氧化酶活性影响的研究

徐宏伟，韩秀霞，杜卫，马爱国

《营养学报》

2006

维生素E对大鼠肝线粒体酶活性的影响

徐宏伟，韩秀霞，杜卫，马爱国

《中国公共卫生》

2005

Low Birth Weight and Renal Function

Jia Rao, Hongwei Xu, Chao Chen

2002

补充抗氧化营养素对青年人群抗氧化能力的影响

石学香，马爱国，梁惠，张秀珍，徐宏伟，杜卫

《营养学报》

2002

维生素C、B6和牛磺酸增强叶酸防畸效果的观察

徐宏伟，马爱国，杜卫，刘颖

《营养学报》

2001

维生素A缺乏对大鼠睾丸组织酶活性的影响

徐宏伟，马爱国，田润华

《卫生研究》

徐宏伟

精选作品

期刊论文

Ubiquitin-specific protease 11 promotes tubular cell senescence via inhibiting p53 ubiquitin degradation during renal fibrosis.

SHROOM3 Deficiency Aggravates Adriamycin-Induced Nephropathy Accompanied by Focal Adhesion Disassembly and Stress Fiber Disorganization

GEN1 as a risk factor for human congenital anomalies of the kidney and urinary tract

USP11 promotes renal tubular cell pyroptosis and fibrosis in UUO mice via inhibiting KLF4 ubiquitin degradation

Minnelide combined with anti-ANGPTL3-FLD monoclonal antibody completely protects mice with adriamycin nephropathy by promoting autophagy and inhibiting apoptosis

Genetic Spectrum of Congenital Anomalies of the Kidney and Urinary Tract in Chinese Newborn Genome Project

Overexpression of long noncoding RNA 4933425B07Rik leads to renal hypoplasia by inactivating Wnt/β-catenin signaling pathway

Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage

N6-Methyladenosine Methylomic Landscape of Ureteral Deficiency in Reflux Uropathy and Obstructive Uropathy

Protective role of endorepellin in renal developmental programming

Human and mouse studies establish TBX6 in Mendelian CAKUT and as a potential driver of kidney defects associated with the 16p11.2 microdeletion syndrome

Biophysical and Structural Characterization of Non-Canonical DNA Structures

KDR siRNA对乳癌细胞凋亡和NES1与RUNX3基因甲基化影响

Expression of Angiopoietin-Like 3 Associated with Puromycin-Induced Podocyte Damage

KDR靶向RNA干扰对MCF-7细胞凋亡的影响(英文)

维生素E对大鼠心肌线粒体ATP酶和抗氧化酶活性影响的研究

维生素E对大鼠肝线粒体酶活性的影响

Low Birth Weight and Renal Function

补充抗氧化营养素对青年人群抗氧化能力的影响

维生素C、B6和牛磺酸增强叶酸防畸效果的观察

维生素A缺乏对大鼠睾丸组织酶活性的影响

会议论文

下调VEGF表达对人乳腺癌细胞凋亡相关基因的影响

大剂量维生素E、C补充对大鼠生物大分子氧化损伤及细胞功能影响的研究

维生素A与维生素E增强叶酸防畸效果的研究

研究方向