百晓学者学者目录

刘文

教授，厦门大学

精选作品

期刊论文

2026

Mitochondrial NADP(H)–dependent de novo dTMP biosynthesis counteracts the cytotoxicity of PARP inhibitors

Qing Li, Tong Shu, Chen Liu, Min Zheng, Yuanpei Li, Lei Zhang, Gao Fan, Wenbin Lu, Huiwen Zhang, Pingping Liu, Xiaoniu He, Hong Zheng, Wen Liu, Jing Ye, Zhenyu Yin, Xianming Deng, Chen‐Song Zhang, Canhua Huang, Han You

Proceedings of the National Academy of Sciences

DOI

2026

Large-scale and high-resolution mass spectrometry-based proteomics defines molecular subtypes of nasopharyngeal carcinoma for therapeutic targeting

Yan Wu, Yaohui He, Guo-Sheng Hu, Zhiqin Li, Qi Li, Xiaotong Chen, Hui-Ying Ling, Wen Liu, Qin Lin

Signal Transduction and Targeted Therapy

DOI

2026

Spatial single-cell landscape of tumor-associated macrophages and their crosstalk with the tumor microenvironment

Rui-chao Nie, Guosheng Hu, Shi-qiang Cao, An Wang, Du-chuang Wang, Wen Liu

Cell Discovery

DOI

2026

Casein kinase 2-mediated phosphorylation of the splicing factor SF3B3 plays a key role in esophageal squamous cell carcinoma progression

Du-chuang Wang, Jiayuan Li, Xiao-bing Wang, Guo-sheng Hu, Rui-chao Nie, Bin Zheng, Yaohui He, Wen Liu

PLoS Biology

DOI

2025

ESRRA通过超级增强子和启动子双重作用调控基因转录促进ERα阳性乳腺癌发展（英文）

郑早早，陈璐，胡国升，彭冰灵，黄琦绚，王铵，王川，刘文

Science Bulletin

2025

Nuclear receptor ESRRA promotes ERα-positive breast cancer through dual action on super enhancers and promoters to regulate gene transcriptional programs

Zaozao Zheng, Lu Chen, Guo-Sheng Hu, Bing‐ling Peng, Qi-Xuan Huang, An Wang, Chuan Wang, Wen Liu

《中国科学通报：英文版》

DOI

2025

PRMT5 encourages cell migration and metastasis of tongue squamous cell carcinoma through methylating ΔNp63α

Shijie Fan, Wenjuan Li, Yucheng Qi, Zejiao Li, Yaohui He, Xiushuang Luo, Xinwen Nie, Jia Wang, Jinqi Ji, Haoran Tian, Yang Cao, Ya Hou, Ning Ji, Zhi‐Xiong Jim Xiao, Xiaobo Wang, Wen Liu, Chenghua Li

Cell Death and Differentiation

DOI

2025

PRMT1 oligomerization regulates RNA-binding protein cascade to promote pancreatic cancer

Yanxia Ru, Xinyi Zhou, Xijiao Wang, Wenxin Sun, Yaohui He, Guo-Sheng Hu, Wenjuan Li, Die Hu, Meizhi Jiang, Zhiming Su, Fengfeng Niu, Gang Chen, Jin-Zhang Zeng, Sen‐Fang Sui, Wen Liu, Yaowang Li, Siming Chen

Life Science Alliance

DOI

2025

PILRα on tumor cells interacts with the T cell surface protein CD99 to suppress antitumor immunity

Lin Xia, Junyi Liu, Chao Yu, Hongwei Lin, Ya-hong Hu, Guo-Sheng Hu, Yaohui He, Yun-yao Chen, Wenxin Luo, Ningshao Xia, Wen Liu

Nature Cancer

DOI

2025

Hypoxia-induced PRMT1 methylates HIF2β to promote breast tumorigenesis via enhancing glycolytic gene transcription

Wenjuan Li, Yan-Chao Chen, Yian Lin, Yi-qin Zou, Guo-Sheng Hu, Jing-jing Yang, Xinyu Y. Nie, Mei-yan Li, Yiran Wang, Yaohui He, Yan Zhao, Yuhua Tan, Xianming Deng, Weiling He, Yan Cheng, Fangmeng Fu, Wen Liu

Cell Reports

DOI

2025

The FBXW7–KMT2 axis in cancer-associated fibroblasts controls tumor growth via an epigenetic-paracrine mechanism

Lu Yin, Jiagui Zhang, Zhipeng Zhu, Xiaojuan Peng, Huiyin Lan, Alex M. Ayoub, Mingjia Tan, Bo O. Zhou, Yaohui He, Siyuan Wang, Yan Lü, Wen Liu, Xiufang Xiong, Jing Huang, Yali Dou, Fengbiao Mao, Yi Sun

Proceedings of the National Academy of Sciences

DOI

2025

A circRNA–mRNA pairing mechanism regulates tumor growth and endocrine therapy resistance in ER-positive breast cancer

Yi Jia, Jiao Du, Xue Chen, Rui-chao Nie, Guo-Sheng Hu, Lei Wang, Yueying Zhang, Shang Chen, Xiao-sha Wen, Dixian Luo, Hua He, Wen Liu

Proceedings of the National Academy of Sciences

DOI

2025

Integrated Analysis of Proteome and Transcriptome Profiling Reveals Pan-Cancer-Associated Pathways and Molecular Biomarkers

Guo-Sheng Hu, Zaozao Zheng, Yaohui He, Du-chuang Wang, Rui-chao Nie, Wen Liu

Molecular & Cellular Proteomics

DOI

2024

长链非编码RNA及其编码的微蛋白在乳腺癌中的功能及其研究进展

温子靖，杜俊，陈雪，刘文

《厦门大学学报(自然科学版)》

2024

A CARM1 Inhibitor Potently Suppresses Breast Cancer Both In Vitro and In Vivo

Bing‐ling Peng, Ting Ran, Xue Chen, Jian-cheng Ding, Zirui Wang, Wenjuan Li, Wen Liu

Journal of Medicinal Chemistry

DOI

2024

CARM1 hypermethylates the NuRD chromatin remodeling complex to promote cell cycle gene expression and breast cancer development

X.P. Chen, Mingfeng Huang, Da-meng Fan, Yaohui He, Wenjuan Zhang, Jian‐cheng Ding, Bing‐ling Peng, Xu Pan, Ya Liu, Jun Du, Ying Li, Zhiying Liu, Bing-lan Xie, Zhijian Kuang, Yi Jia, Wen Liu

Nucleic Acids Research

DOI

2024

Peptide Inhibitor Targeting the Extraterminal Domain in BRD4 Potently Suppresses Breast Cancer Both In Vitro and In Vivo

Qi-xuan Huang, Da-meng Fan, Zaozao Zheng, Ting Ran, Ao Bai, Rong-quan Xiao, Guo-Sheng Hu, Wen Liu

Journal of Medicinal Chemistry

DOI

2024

LncRNA LUESCC promotes esophageal squamous cell carcinoma by targeting the miR-6785-5p/NRSN2 axis

Song-tao Xue, Shi-qiang Cao, Jian‐cheng Ding, Wen-juan Li, Guo-Sheng Hu, Jian-cong Zheng, Xiao Lin, Chun Chen, Wen Liu, Bin Zheng

Cellular and Molecular Life Sciences

DOI

2024

CircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma

Shi-qiang Cao, Song-tao Xue, Wen-juan Li, Guo-Sheng Hu, Zhigang Wu, Jian-cong Zheng, Shuliang Zhang, Xiao Lin, Chun Chen, Wen Liu, Bin Zheng

Cell Death Discovery

DOI

2024

Targeting the PHF8/YY1 axis suppresses cancer cell growth through modulation of ROS

Xiaonan Wu, Jia-yuan Li, Qi He, Boqun Li, Yaohui He, Xu Pan, Mingyue Wang, Rui Sang, Jian-cheng Ding, Xiang Gao, Zhen Wu, Wen Liu

Proceedings of the National Academy of Sciences

DOI

2023

Targeting PRMT1-mediated SRSF1 methylation to suppress oncogenic exon inclusion events and breast tumorigenesis

Wenjuan Li, Ying Huang, Yi-an Lin, Baoding Zhang, Meiyan Li, Yi-qin Zou, Guo-Sheng Hu, Yaohui He, Jing-jing Yang, Bing-lan Xie, Haihua Huang, Xianming Deng, Wen Liu

Cell Reports

DOI

2023

The novel CDK9 inhibitor, XPW1, alone and in combination with BRD4 inhibitor JQ1, for the treatment of clear cell renal cell carcinoma

Zhijian Kuang, Kaiqiang Guo, Yin Cao, Mengxue Jiang, Chaojie Wang, Qiaoqiong Wu, Guo-Sheng Hu, Mingtao Ao, Mingfeng Huang, Jingbo Qin, Taige Zhao, Lu Sheng, Cuiling Sun, Mingyu Li, Tong Wu, Wen Liu, Meijuan Fang

British Journal of Cancer

DOI

2023

A deregulated m 6 A writer complex axis driven by BRD4 confers an epitranscriptomic vulnerability in combined DNA repair–targeted therapy

Lu Xiao, Lichao Peng, Jian-cheng Ding, Yuanpei Li, Qing Li, Mengchen Rao, Tong Shu, Xiaoniu He, Chen Liu, Jing Ye, Wen Liu, Han You

Proceedings of the National Academy of Sciences

DOI

2023

Characterization of circSEC11A as a novel regulator of Iodine-125 radioactive seed-induced anticancer effects in hepatocellular carcinoma via targeting ZHX2/GADD34 axis

Dong Li, Wujie Wang, Bin Liu, Die Jin, Yang Wang, Guanghui He, Lei Guo, Wen Liu, Yuliang Li

Cell Death Discovery

DOI

2023

Estrogen‐Induced LncRNA, LINC02568, Promotes Estrogen Receptor‐Positive Breast Cancer Development and Drug Resistance Through Both InTrans and In Cis Mechanisms

Xue Chen, Jian‐cheng Ding, Guo-Sheng Hu, Xing-yi Shu, Yan Liu, Jun Du, Zi‐jing Wen, Jun‐yi Liu, Hai‐hua Huang, Guohui Tang, Wen Liu

Advanced Science

DOI

2023

Data from A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer

Nan Ding, A‐Bin You, Hu Yang, Guo-Sheng Hu, Chun-Ping Lai, Wen Liu, Feng Ye

DOI

2023

ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer

Yi Jia, Lei Wang, Jiao Du, Mingyue Wang, Haifeng Shen, Zhiying Liu, Yao Qin, Jing Liu, Guo-Sheng Hu, Rong-quan Xiao, Jian‐cheng Ding, Xiaoyan Chen, Hongjiao Wang, Haihua Huang, Gaoliang Ouyang, Wen Liu

Developmental Cell

DOI

2023

Isobaric Stable Isotope N‐Phosphorylation Labeling (iSIPL) for Ultrasensitive Proteome Quantification

Xiaoyu Wang, Chun‐Jing Chen, Yaohui He, Lian‐Shuai Ding, Yifan Wu, Cheng‐Ting Huang, Jun Wu, Rong Ding, Yuhua Xue, Zhi‐Wei Lin, Pengxiang Xu, Yile Wu, Wen Liu, Jijun Li, Siming Chen, Yufen Zhao, Jiyang Dong, Qiang Zhou, Xiang Gao

Angewandte Chemie

DOI

2023

CircPVT1 promotes ER‐positive breast tumorigenesis and drug resistance by targeting ESR1 and MAVS

Yi Jia, Lei Wang, Guo-Sheng Hu, Yueying Zhang, Jiao Du, Jian‐cheng Ding, Xiang Ji, Haifeng Shen, Hai‐hua Huang, Feng Ye, Wen Liu

The EMBO Journal

DOI

2023

A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer

Nan Ding, A‐Bin You, Hu Yang, Guo-Sheng Hu, Chun-Ping Lai, Wen Liu, Feng Ye

Clinical Cancer Research

DOI

2023

piR-36249 and DHX36 together inhibit testicular cancer cells progression by upregulating OAS2

Qianqian Wang, Peize Chen, Xiaorong Wang, Yueming Wu, Kaiguo Xia, Xiangyu Mu, Qiang Xuan, Jun Ying Xiao, Yaohui He, Wen Liu, Xiaoyuan Song, Fei Sun

Non-coding RNA Research

DOI

2022

Long non-coding RNA LINC00680 functions as a ceRNA to promote esophageal squamous cell carcinoma progression through the miR-423-5p/PAK6 axis

Songtao Xue, Bin Zheng, Shi-qiang Cao, Jian‐cheng Ding, Guo-Sheng Hu, Wen Liu, Chun Chen

Molecular Cancer

DOI

2022

A feedforward circuit between KLF5 and lncRNA KPRT4 contributes to basal-like breast cancer

Guangshi Du, Jian Sun, Zhen Li, Qian Zhang, Wenjing Liu, Chuanyu Yang, Ping Zhao, Xinye Wang, Qiyan Yin, Yao Luo, Jinhuan Song, Yi Wen, Haixia Wang, Chuan‐Huizi Chen, Guo-Sheng Hu, Zhongmei Zhou, Xiaoyun Mao, Wen Liu, Zhenzhen Liu, Dewei Jiang, Ceshi Chen

Cancer Letters

DOI

2022

CPPA: A Web Tool for Exploring Proteomic and Phosphoproteomic Data in Cancer

Guo-Sheng Hu, Zaozao Zheng, Yaohui He, Du-chuang Wang, Wen Liu

Journal of Proteome Research

DOI

2022

METTL3 acetylation impedes cancer metastasis via fine-tuning its nuclear and cytosolic functions

Yuanpei Li, Xiaoniu He, Lu Xiao, Zhicheng Gong, Qing Li, Lei Zhang, Ronghui Yang, Chengyi Wu, Jialiang Huang, Jian‐cheng Ding, Yaohui He, Wen Liu, Ceshi Chen, Bin Cao, Dawang Zhou, Yufeng Shi, Juxiang Chen, Chuangui Wang, Shengping Zhang, Jian Zhang, Jing Ye, Han You

Nature Communications

DOI

2022

Super-enhancer-controlled positive feedback loop BRD4/ERα–RET–ERα promotes ERα-positive breast cancer

Zaozao Zheng, Lin Xia, Guo-Sheng Hu, Junyi Liu, Ya-hong Hu, Yu-jie Chen, Peng Jia-yin, Wenjuan Zhang, Wen Liu

Nucleic Acids Research

DOI

2022

A specific JMJD6 inhibitor potently suppresses multiple types of cancers both in vitro and in vivo

Rong-quan Xiao, Ting Ran, Qi-xuan Huang, Guo-Sheng Hu, Da-meng Fan, Yi Jia, Wen Liu

Proceedings of the National Academy of Sciences

DOI

2022

CDK1 Promotes Epithelial–Mesenchymal Transition and Migration of Head and Neck Squamous Carcinoma Cells by Repressing ∆Np63α-Mediated Transcriptional Regulation

Huimin Chen, Ke Hu, Ying Xie, Yucheng Qi, Wenjuan Li, Yaohui He, Shijie Fan, Wen Liu, Chenghua Li

International Journal of Molecular Sciences

DOI

2022

Roles of circRNAs in the Tumorigenesis and Metastasis of HCC: A Mini Review

Yichen Liu, Lei Wang, Wen Liu

Cancer Management and Research

DOI

2022

Deep proteome profiling promotes whole proteome characterization and drug discovery for esophageal squamous cell carcinoma

Wei Liu, Yongping Cui, Wen Liu, Zhihua Liu, Li‐Yan Xu, En‐Min Li

Cancer Biology and Medicine

DOI

2022

YB-1 is a positive regulator of KLF5 transcription factor in basal-like breast cancer

Dewei Jiang, Ting Hu Qiu, Junjiang Peng, Siyuan Li, Tala, Wenlong Ren, Chuanyu Yang, Yi Wen, Chuan‐Huizi Chen, Chuan-Huizi Chen, Jian Sun, Yingying Wu, Rong Liu, Jun Zhou, Kongming Wu, Wen Liu, Xiaoyun Mao, Zhongmei Zhou, Ceshi Chen, Ceshi Chen

Cell Death and Differentiation

DOI

2021

The Dual Function of KDM5C in Both Gene Transcriptional Activation and Repression Promotes Breast Cancer Cell Growth and Tumorigenesis

Hai-Feng Shen, Wen-juan Zhang, Ying Huang, Yao-hui He, Guo-Sheng Hu, Lei Wang, Bingling Peng, Jia Yi, Ting-Ting Li, R. Rong, Xiao-yan Chen, Jun-Yi Liu, Wenjuan Li, Kenny Ohgi, Shaowei Li, M. Rosenfeld, Wen Liu

Advancement of science

DOI

2021

Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting

Wei Liu, Wei Liu, Lei Xie, Yao-Hui He, Zhi-Yong Wu, Lu-Xin Liu, Xuefeng Bai, Dan-Xia Deng, Xiu‐E Xu, Lian-Di Liao, Wan Lin, Jing-Hua Heng, Xin Xu, Liu Peng, Qingfeng Huang, Cheng-Yu Li, Zhi-Da Zhang, Wei Ting Wang, Guo-Rui Zhang, Xiang Gao, Shaohong Wang, Chun-Quan Li, Li-Yan Xu, Wen Liu, Wen Liu, En‐Min Li

Nature Communications

DOI

2021

OTUD7B Deubiquitinates LSD1 to Govern Its Binding Partner Specificity, Homeostasis, and Breast Cancer Metastasis

Zhicheng Gong, Aicun Li, Jian‐cheng Ding, Qing Li, Lei Zhang, Yuanpei Li, Zhe Meng, Fei Chen, Jialiang Huang, Dawang Zhou, Ronggui Hu, Jing Ye, Wen Liu, Han You

Advanced Science

DOI

2021

BRD4 inhibition boosts the therapeutic effects of epidermal growth factor receptor-targeted chimeric antigen receptor T cells in glioblastoma

Lin Xia, Junyi Liu, Zaozao Zheng, Yu-jie Chen, Jian‐cheng Ding, Ya-hong Hu, Guo-Sheng Hu, Ningshao Xia, Wen Liu

Molecular Therapy

DOI

2021

Arginine methyltransferase PRMT5 methylates and stabilizes KLF5 via decreasing its phosphorylation and ubiquitination to promote basal-like breast cancer

Xinye Wang, Ting Hu Qiu, Yingying Wu, Chuanyu Yang, Yi Li, Guangshi Du, Yaohui He, Wen Liu, Rong Liu, Chuan-huizi Chen, Chuan-huizi Chen, Yujie Shi, Jingxuan Pan, Jia Zhou, Dewei Jiang, Ceshi Chen, Ceshi Chen

Cell Death and Differentiation

DOI

2021

Targeting Triple-Negative Breast Cancer with Combination Therapy of EGFR CAR T Cells and CDK7 Inhibition

Lin Xia, Zaozao Zheng, Junyi Liu, Yu-jie Chen, Jian‐cheng Ding, Guo-Sheng Hu, Ya-hong Hu, Suling Liu, Wenxin Luo, Ningshao Xia, Wen Liu

Cancer Immunology Research

DOI

2021

Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth

Wenjuan Li, Yaohui He, Jing-jing Yang, Guo-Sheng Hu, Yi-an Lin, Ting Ran, Bing‐ling Peng, Bing-lan Xie, Mingfeng Huang, Xiang Gao, Haihua Huang, Helen He Zhu, Feng Ye, Wen Liu

Nature Communications

DOI

2020

A hypermethylation strategy utilized by enhancer-bound CARM1 to promote estrogen receptor α-dependent transcriptional activation and breast carcinogenesis

Bingling Peng, Wenjuan Li, Jian-Cheng Ding, Yao-hui He, T. Ran, Binglan Xie, Zi-rui Wang, Hai-Feng Shen, R. Xiao, Wei-wei Gao, Tian-yi Ye, Xiang Gao, Wen Liu

Theranostics

DOI

2020

Estrogen-induced circRNA, circPGR, functions as a ceRNA to promote estrogen receptor-positive breast cancer cell growth by regulating cell cycle-related genes

Lei Wang, Yi Jia, Lingyun Lu, Yueying Zhang, Lan Wang, Guo-Sheng Hu, Yi-chen Liu, Jian‐cheng Ding, Haifeng Shen, Fangqing Zhao, Haihua Huang, Wen Liu

Theranostics

DOI

2020

SRPK1 acetylation modulates alternative splicing to regulate cisplatin resistance in breast cancer cells

Cheng Wang, Zhihong Zhou, Charannya Sozheesvari Subhramanyam, Qiong Cao, Zealyn Shi‐Lin Heng, Wen Liu, Xiang‐Dong Fu, Qidong Hu

Communications Biology

DOI

2020

LncRNA LUCRC Regulates Colorectal Cancer Cell Growth and Tumorigenesis by Targeting Endoplasmic Reticulum Stress Response

Guohui Tang, Xue Chen, Jian‐cheng Ding, Jun Du, Xiaoting Lin, Lu Xia, Jiabian Lian, Ye Feng, HE Xiu-sheng, Wen Liu

Frontiers in Genetics

DOI

2020

Acetylation dependent functions of Rab22a-NeoF1 Fusion Protein in Osteosarcoma

Xiaoting Liang, Xin Wang, Yaohui He, Yuanzhong Wu, Li Zhong, Wen Liu, Dan Liao, Tiebang Kang

Theranostics

DOI

2019

In Silico Discovery of JMJD6 Inhibitors for Cancer Treatment

Ting Ran, Rong-quan Xiao, Qi-xuan Huang, Haoliang Yuan, Tao Lu, Wen Liu

ACS Medicinal Chemistry Letters

DOI

2019

Virtual Screening with a Structure-Based Pharmacophore Model to Identify Small-Molecule Inhibitors of CARM1

Ting Ran, Wenjuan Li, Bing‐ling Peng, Bing-lan Xie, Tao Lu, Shuai Lü, Wen Liu

Journal of Chemical Information and Modeling

DOI

2019

Inhibition of super enhancer downregulates the expression of KLF5 in basal-like breast cancers

Chuan‐Huizi Chen, Nong Yang, Yongchang Zhang, Jian‐cheng Ding, Wenjuan Zhang, Rong Liu, Wen Liu, Ceshi Chen

International Journal of Biological Sciences

DOI

2018

JMJD6 Licenses ERα-Dependent Enhancer and Coding Gene Activation by Modulating the Recruitment of the CARM1/MED12 Co-activator Complex

Wei-wei Gao, R. Xiao, Wen-juan Zhang, Yi-ren Hu, Bingling Peng, Wenjuan Li, Yao-hui He, Hai-Feng Shen, Jian-Cheng Ding, Qi-Xuan Huang, Tian-yi Ye, Ying Li, Zhi-ying Liu, Rong Ding, M. Rosenfeld, Wen Liu

Molecules and Cells

DOI

2018

PRMT2 links histone H3R8 asymmetric dimethylation to oncogenic activation and tumorigenesis of glioblastoma

Feng Dong, Qian Li, Chao Yang, Dawei Huo, Xing Wang, Chunbo Ai, Yu Kong, Xiaoyu Sun, Wen Wang, Yan Zhou, Xing Liu, Wěi Li, Weiwei Gao, Wen Liu, Chunsheng Kang, Xudong Wu

Nature Communications

DOI

2017

Glucocorticoid Receptor:MegaTrans Switching Mediates the Repression of an ERα-Regulated Transcriptional Program

Feng Yang, Qi Ma, Zhijie Liu, Wenbo Li, Yuliang Tan, Chunyu Jin, Wubin Ma, Yiren Hu, Jia Shen, Kenneth A. Ohgi, Francesca Telese, Wen Liu, Michael G. Rosenfeld

Molecular Cell

DOI

2015

Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation

Wenbo Li, Yi-ren Hu, Soohwan Oh, Qi Ma, Daria Merkurjev, Xiaoyuan Song, Xiaoping Zhou, Zhijie Liu, B. Tanasa, Xin-Jian He, A. Chen, Kenny Ohgi, Jie Zhang, Wen Liu, M. Rosenfeld

Molecules and Cells

DOI

2013

Brd4 and JMJD6-associated Anti-pause Enhancers in Regulation of Transcriptional Pause Release

Wen Liu, Qi Ma, Kaki Wong, Wenbo Li, K. Ohgi, Jie Zhang, A. Aggarwal, M. Rosenfeld

Cell

DOI

2012

mHMM (multivariate hidden Markov model) application in studying BRD4 and JMJD6 function cooperatively on promoter-proximal polymerase-II (Pol II) pausing release

Qi Ma, Wen Liu, M. Rosenfeld

ACM International Conference on Bioinformatics, Computational Biology and Biomedicine

DOI

预印本

2023

Targeting Cyclin-Dependent Kinase 9 (CDK9) As a Novel Therapeutic Strategy for Clear Cell Renal Cell Carcinoma

Zhijian Kuang, Kaiqiang Guo, Chaojie Wang, Mengxue Jiang, Qiaoqiong Wu, Guo-Sheng Hu, Yin Cao, Mingtao Ao, Mingfeng Huang, Jingbo Qin, Taige Zhao, Lu Sheng, Cuiling Sun, Mingyu Li, Tong Wu, Wen Liu, Meijuan Fang

SSRN Electronic Journal

DOI

研究方向

表观遗传调控子，转录因子和核受体在乳腺癌，前列腺癌等癌症及其炎症反应中的作用分子机制

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