百晓学者学者目录

张翀

副教授、教授、讲师，湖北中医药大学

精选作品

期刊论文

2026

癸酸通过活化CD8+T细胞促进小鼠黑色素瘤B16F10细胞皮下荷瘤模型的抗肿瘤免疫反应

张翀，金海振，周纯，胡惠惠，王娟，王秦兰

《中国肿瘤生物治疗杂志》

2026

紫花苜蓿和金银花提取物复配对高脂日粮诱导的大鼠脂代谢紊乱的调节作用

郭哲，康钰晨，张翀，周鑫，刘欣悦，马如新，蒋曹德

《中国兽医学报》

2026

Cardiotoxicity of Targeted Therapies in Hematologic Malignancies: From Molecular Mechanisms to Clinical Management

Meng-meng Lin, Shanshan Shi, Chong Zhang, Jianmin Yang, Rong Dong, Neng-Ming Lin, Xiangmin Tong, Yang-Ling Li

Current Treatment Options in Oncology

DOI

2025

Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer

Chong Zhang, Zuo-yan Zhang, Yue-Yi Wu, Yu-Chen Wu, Jing Cheng, Kai-Zhi Luo, Zhidi Li, Man-Man Zhang, Jian Wang, Xue-Sen Zhang, Yang-Ling Li

bioRxiv

DOI

2025

Vortioxetine exhibits anti-glioblastoma activity via the PI3K-Akt signaling pathway

Huan-qi Zhang, Daoming Zhang, Zhi-Zhen Huang, Jing Cheng, Chong Zhang, N. Lin, Yang-Ling Li

Iranian Journal of Basic Medical Sciences

DOI

2024

网络药理学方法联合体外实验初探金水六君煎辅助放化疗治疗恶性黑色素瘤的分子机制

洪学敏，彭圆，张翀，杨莉，陈娟平

《沈阳药科大学学报》

2023

Pharmacologic and non-pharmacologic interventions for emotional lability: A meta-analysis

Jame A. Agapoff, Zhang Chong, Matthew Meek, Gerrit I. van Schalkwyk

Neuroscience And Biobehavioral Reviews，Vol. 149

DOI

2023

基于Wnt信号通路分析葛根素对大鼠颈动脉球囊损伤术再狭窄的干预作用

张翀，李丽，祁卫华，赵玉杰，张红霞

《中西医结合心脑血管病杂志》

2023

Triacanthine enhances the sensitivity of colorectal cancer cells to 5-fluorouracil by regulating RRM2.

Ye-han Liu, M. Shen, Yu-Chen Wu, Kai-Zhi Luo, Jian-Kang Zhang, Zheng Wang, Ziwen Chen, Jie Li, Si Wu, Chong Zhang, N. Lin, Yang-Ling Li

Phytomedicine

DOI

2022

莪术提取物对大鼠颈动脉PCI术后血管再狭窄预防作用及机制研究

赵玉杰，张红霞，李丽，祁卫华，张翀

《辽宁中医药大学学报》

2022

Ferroptosis in cancer and cancer immunotherapy

Lei Zhao, Xiaoxue Zhou, Feng Xie, Lei Zhang, Hai-Yan Yan, Jun Huang, Chong Zhang, Fang-Fang Zhou, Jun Chen, Long Zhang

Cancer Communications

DOI

2022

The Overexpression of SLC25A13 Predicts Poor Prognosis and Is Correlated with Immune Cell Infiltration in Patients with Skin Cutaneous Melanoma

Yue Lv, Chunhui Yuan, Lu Han, Gaowei Huang, Ling Ju, L. Chen, Hai-Ying Han, Chong Zhang, Ling-Hui Zeng

Disease Markers

DOI

2022

Erratum to DYRK1A suppression restrains Mcl-1 expression and sensitizes NSCLC cells to Bcl-2 inhibitors

Yang-Ling Li, Dongmei Zhou, Shuang Xu, Mingjun Rao, Zuo-yan Zhang, Lin-wen Wu, Chong Zhang, Neng-Ming Lin

Cancer Biology and Medicine

DOI

2022

Harmine reinforces the effects of regorafenib on suppressing cell proliferation and inducing apoptosis in liver cancer cells

Zi-Yi Chen, Jie Li, Shuoru Zhu, Zhi-di Li, Jia-Lin Yu, Jie Wu, Chong Zhang, Ling-Hui Zeng

Experimental and Therapeutic Medicine

DOI

2022

DYRK1A reinforces epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma via cooperatively activating STAT3 and SMAD

Yang-Ling Li, Man-man Zhang, Lin-wen Wu, Ye-han Liu, Zuo-yan Zhang, Lingjuan Zeng, N. Lin, Chong Zhang

Journal of Biomedical Sciences

DOI

2022

DYRK1A suppression attenuates HIF-1α accumulation and enhances the anti-liver cancer effects of regorafenib and sorafenib under hypoxic conditions

Chong Zhang, Lin-wen Wu, Zhi-di Li, Man-man Zhang, Jie Wu, Fei-hua Du, Ling-Hui Zeng, Yang-Ling Li

International Journal of Oncology

DOI

2021

Enhanced anticancer activity by the combination of vinpocetine and sorafenib via PI3K/AKT/GSK-3β signaling axis in hepatocellular carcinoma cells

Zuo-yan Zhang, S. Dong, Ye-han Liu, Man-man Zhang, Jian-Kang Zhang, Hua-jian Zhu, Ji-Aan Shao, Hua-Qing Liu, Yang-Ling Li, Chong Zhang, Ling-Hui Zeng

Anti-Cancer Drugs

DOI

2020

DYRK1A suppression restrains Mcl-1 expression and sensitizes NSCLC cells to Bcl-2 inhibitors

Yang-Ling Li, Dongmei Zhou, Shuang Xu, Mingjun Rao, Zuo-yan Zhang, Lin-wen Wu, Chong Zhang, N. Lin

Cancer Biology and Medicine

DOI

2020

A natural anthraquinone derivative shikonin synergizes with AZD9291 against wtEGFR NSCLC cells through reactive oxygen species-mediated endoplasmic reticulum stress.

Xiu Hu, Zuo-yan Zhang, Lin-wen Wu, Ling-Hui Zeng, Hui Chen, Hua-jian Zhu, Jian-Kang Zhang, Ji-Aan Shao, Chong Zhang, Yang-Ling Li, N. Lin

Phytomedicine

DOI

2020

ApoC1 promotes the metastasis of clear cell renal cell carcinoma via activation of STAT3

Yang-Ling Li, Lin-wen Wu, Ling-Hui Zeng, Zuo-yan Zhang, Wei Wang, Chong Zhang, N. Lin

Oncogene

DOI

2020

Metformin Down Regulate Mcl-1 and Induce Apoptosis of Human Oral Cancer Cells Through MiR-26a

Chong Zhang

2019

中医药在肿瘤免疫微环境中的作用

俞文峰，牛越群，吕望，张翀，胡坚

《浙江中西医结合杂志》

2019

对分课堂在中医基础理论教学中培养学生象思维的探索

张翀，万可，彭圆

《时珍国医国药》

2019

金水六君煎延缓皮肤老化机制探析

张翀，田黎明，周密思，周玲，王平，彭圆

《中华中医药杂志》

2019

DYRK1A inhibition suppresses STAT3/EGFR/Met signalling and sensitizes EGFR wild‐type NSCLC cells to AZD9291

Yang-Ling Li, Ke Ding, Xiu Hu, Lin-wen Wu, Dongmei Zhou, Mingjun Rao, N. Lin, Chong Zhang

Journal of Cellular and Molecular Medicine

DOI

2019

BAY 87-2243 sensitizes hepatocellular carcinoma Hep3B cells to histone deacetylase inhibitors treatment via GSK-3β activation.

Yang-Ling Li, Mingjun Rao, Ning-Yu Zhang, Lin-wen Wu, N. Lin, Chong Zhang

Experimental and Therapeutic Medicine

DOI

2019

High-dose vitamin C suppresses the invasion and metastasis of breast cancer cells via inhibiting epithelial-mesenchymal transition

Linghui Zeng, Qingmei Wang, Lin-Yi Feng, Yuqi Ke, Qianlang Xu, Anyi Wei, Chong Zhang, Rong-Biao Ying

OncoTargets and Therapy

DOI

2019

Suppression of LSD1 enhances the cytotoxic and apoptotic effects of regorafenib in hepatocellular carcinoma cells.

Lin-wen Wu, Dongmei Zhou, Zuo-yan Zhang, Jian-Kang Zhang, Hua-jian Zhu, N. Lin, Chong Zhang

Biochemical and Biophysical Research Communications - BBRC

DOI

2019

Harmine suppresses the proliferation of pancreatic cancer cells and sensitizes pancreatic cancer to gemcitabine treatment

Lin-wen Wu, Jian-Kang Zhang, Mingjun Rao, Zuo-yan Zhang, Hua-jian Zhu, Chong Zhang

OncoTargets and Therapy

DOI

2018

Evodiamine induces apoptosis and promotes hepatocellular carcinoma cell death induced by vorinostat via downregulating HIF-1α under hypoxia.

Yang-Ling Li, Ning-Yu Zhang, Xiu Hu, Jia-ling Chen, Mingjun Rao, Lin-wen Wu, Qing-yu Li, Bo Zhang, Wei Yan, Chong Zhang

Biochemical and Biophysical Research Communications - BBRC

DOI

2018

The anti-tumor effect of regorafenib in lung squamous cell carcinoma in vitro.

Xiu Hu, Lin-wen Wu, Zuo-yan Zhang, Mengjiao Chen, Yang-Ling Li, Chong Zhang

Biochemical and Biophysical Research Communications - BBRC

DOI

2018

Shikonin sensitizes wild-type EGFR NSCLC cells to erlotinib and gefitinib therapy

Yang-Ling Li, Xiu Hu, Qing-yu Li, Fei Wang, Bo Zhang, Ke Ding, B. Tan, N. Lin, Chong Zhang

Molecular Medicine Reports

DOI

2018

Synergistic antitumor activity of aspirin and erlotinib: Inhibition of p38 enhanced aspirin plus erlotinib-induced suppression of metastasis and promoted cancer cell apoptosis.

Xiu Hu, Lin-wen Wu, Xu Weng, N. Lin, Chong Zhang

Oncology Letters

DOI

2017

中医基础理论“LBL-CBS-PBC”联合教学法培养学生中医思维方式的探讨

冯新玲，杨化冰，张翀

《时珍国医国药》

2017

High glucose induces the aging of mesenchymal stem cells via Akt/mTOR signaling

Da-Yong Zhang, Hui-Fei Lu, Zhongxing Chen, Yayan Wang, Jiuzhou Lin, Shan Xu, Chong Zhang, Baoming Wang, Zhanggen Yuan, Xiao-qian Feng, Xuefan Jiang, Jian-Ping Pan

Molecular Medicine Reports

DOI

2017

TcpC secreting uropathogenic E. coli promoted kidney cells to secrete MIP-2 via p38 MAPK pathway.

Yujie He, Jie Fang, Chong Zhang, Jun Pan, Qi Jin, Yingzhi Yang, Lin-Yao Wang, Baoming Wang, Da-Yong Zhang, Jian-Ping Pan

Molecular Medicine Reports

DOI

2016

Epothilone B induces apoptosis and enhances apoptotic effects of ABT-737 on human cancer cells via PI3K/AKT/mTOR pathway

Yang-Ling Li, Jiao Sun, Xiu Hu, Yi-ni Pan, Wei Yan, Qing-yu Li, Fei Wang, N. Lin, Chong Zhang

Journal of Cancer Research and Clinical Oncology

DOI

2016

Nedaplatin enhanced apoptotic effects of ABT-737 in human cancer cells via Mcl-1 inhibition.

Chong Zhang, Yang-Ling Li, Xu Weng, Li-yan Li, Ming Zhou, Da-Yong Zhang, N. Lin

Oncology Letters

DOI

2016

Evodiamine induces apoptosis and enhances apoptotic effects of erlotinib in wild-type EGFR NSCLC cells via S6K1-mediated Mcl-1 inhibition

Yang-Ling Li, Yi-ni Pan, W-J Wu, Shi-ying Mao, Jiao Sun, Yi-Ming Zhao, Jing-Yin Dong, Da-Yong Zhang, Jian-Ping Pan, Chong Zhang, N. Lin

Medical Oncology

DOI

2015

补脏通络方含药血清对高糖环境下人脐静脉内皮细胞NO、eNOS及MMP9/TIMP1表达的影响

杨化冰，张翀

《时珍国医国药》

2015

Coenzyme Q10 Inhibits the Aging of Mesenchymal Stem Cells Induced by D-Galactose through Akt/mTOR Signaling

Da-Yong Zhang, Bingxi Yan, Shan-shan Yu, Chong Zhang, Baoming Wang, Yayan Wang, Jun-bo Wang, Zhanggen Yuan, Lihuang Zhang, Jian-Ping Pan

Oxidative Medicine and Cellular Longevity

DOI

2015

Anti-metastatic effects of DNA vaccine encoding single-chain trimer composed of MHC I and vascular endothelial growth factor receptor 2 peptide.

Rui-Ling Chen, Sheng-Chao Wang, Yun-Liang Yao, Yun Zhou, Chong Zhang, Jie Fang, Da-Yong Zhang, Lihuang Zhang, Jian-Ping Pan

Oncology Report

DOI

2014

原发性高血压患者WNK-SPAK激酶通路的表达及饮食干预的影响

黄方舟，常娟，李蓉，黄花，于霞，卢英民，朱逸，蒋更如，张翀

《中国中西医结合肾病杂志》

2014

增液行舟方药对津亏便秘衰老模型水通道蛋白表达的影响

彭圆，田黎明，张翀，严进，田代志，王平

《时珍国医国药》

2014

Role of p38 MAPK in enhanced human cancer cells killing by the combination of aspirin and ABT-737

Chong Zhang, Jing Shi, Shi-ying Mao, Ya-Si Xu, Dan Zhang, Lin-Yi Feng, Bo Zhang, You-You Yan, Si-cong Wang, Jian-Ping Pan, Yougang Yang, N. Lin

Journal of Cellular and Molecular Medicine

DOI

2013

便秘对小鼠皮肤、肺组织水通道蛋白表达的影响

彭圆，田黎明，张翀，田代志，严进，郭岚，王平

《时珍国医国药》

2013

增液承气汤对老年津亏便秘模型氧化应激的影响

彭圆，王平，程静，张翀，田代志

《新中医》

2013

[TcpC induces apoptosis of human vascular endothelial cells and its mechanisms].

Chong Zhang, Jia-Le Zhou, Jie Fang, Da-Yong Zhang, Baoyu Wang, Rui-Ling Chen, Jian-Ping Pan

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences

DOI

2013

Wnt/β-catenin signaling induces the aging of mesenchymal stem cells through promoting the ROS production

Da-Yong Zhang, Yung-Wei Pan, Chong Zhang, Binghui Yan, Shan-shan Yu, Dong-ling Wu, Meng-meng Shi, Kai Shi, Xin-xiao Cai, Shuang-shuang Zhou, Jun-bo Wang, Jian-Ping Pan, Li-huang Zhang

Molecular and Cellular Biochemistry

DOI

2013

Sunitinib enhanced the effect of combretastatin A-4 by inducing apoptosis in vitro

Chong Zhang, Shuang-shuang Zhou, N. Lin, Da-Yong Zhang, Hua Zhou, Si-cong Wang, Xiao Shuai, Jian-Ping Pan, Li-huang Zhang

DOI

2013

Enhanced antitumor activity by the combination of dasatinib and combretastatin A-4 in vitro and in vivo.

Chong Zhang, Shuang-shuang Zhou, Xiang-Rong Li, Baoyu Wang, N. Lin, Lin-Yi Feng, Da-Yong Zhang, Li-huang Zhang, Jun-bo Wang, Jian-Ping Pan

Oncology Report

DOI

2013

[TcpC induces apoptosis of macrophages through promoting ROS production].

Da-Yong Zhang, Yi Lin, F. He, Jie Fang, Chong Zhang, Baoyu Wang, Jian-Ping Pan

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences

2010

邱幸凡教授治疗肺癌的经验

张翀

《世界中西医结合杂志》

2010

扶正解毒通络抗肿瘤转移的思路探讨

张翀，朱寒阳，张波

《世界中西医结合杂志》

2008

益气活血化瘀法对D-半乳糖衰老模型小鼠行为学的影响

张翀，王进

《湖北中医杂志》

2008

WNK激酶的研究进展

张翀，陈楠

《中国细胞生物学学报》

2008

从藏象理论论股骨头缺血性坏死之防治

王进，张翀，邱少波

《辽宁中医药大学学报》

会议论文

2017

衷中参西辨病辨证论治心力衰竭

张翀

《2017年第五次世界中西医结合大会论文摘要集（下册）》

DOI

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