苟德明｜深圳大学｜学者主页

2026

Metabolomic and lipidomic signatures associated with clinical improvement after balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension

Jinglin Tian, Su-Gang Gong, P. Yuan, Jingru Huang, Xin-Cheng Li, Jun Wang, Tao Wang, Zhenchi Li, Lan Wang, Deming Gou

Chinese Medical Journal - Pulmonary and Critical Care Medicine

2026

Integrative profiling of multi-modal plasma cfRNA signatures enables detection and prognostic risk stratification in breast cancer

Jun Wang, Liu Yang, Kai Fang, Hongxian Wang, Jianxia Chen, Binbin Tan, Lirong Shu, Jinfeng Ye, Jiayu Wu, Xinyang Lin, Deming Gou, Yun Wang

Genomics

DOI

2026

Omaveloxolone Driven NRF2 Activation as a Novel Therapeutic Strategy for Pulmonary Hypertension

Chuangjia Huang, June Bai, Ang Luo, Lei Yang, Xingting Wang, Linlin Dang, Changlei Bao, Jinsheng Zhu, Z Chen, Bitao Wu, Jintao Long, Jieyi Feng, Zinan Luo, Yingying Xiao, Hanliang Sun, Shuxin Liang, Li Zhang, Jing Hua, Deming Gou, Ankit A. Desai, Li Li, Caojin Zhang, Aiai Chu, Haiyang Tang

Hypertension

DOI

2026

Plasma miRNA signature for the diagnosis of pulmonary tuberculosis in symptomatic patients

Yunlong Hu, Huihua Zhang, Yuzhong Xu, Hao Yang, Qing Yu, Nick Cai, Jinjin Xu, Yue Zhang, Da Liu, Kang Kang, Siwei Mo, Sinan Li, Jingjia Zhang, Peijun Tang, Yaoju Tan, Jiang Zeng, Tianyu Zhong, Qianting Yang, Wenfei Wang, Dayong Gu, Chuanzhi Zhu, Yuping Ning, Kehong Zhang, Youchao Dai, Chenyan Shi, Dachuan Lin, Ling Ji, Yi Cai, Deming Gou, Xinchun Chen

Thorax

DOI

2026

THBS4 Regulates Pulmonary Hypertension via TGF-β/SMAD2 Signaling

Jie Zeng, Dengyuan Li, Jun Wang, Rong Wang, Zhenming Huang, Dan Bai, Xiaohua Liu, Danxiong Sun, Gaohui Fu, Kang Kang, Xiaojia Liu, Liu Yang, Feilong Zhao, Lingjie Luo, Rufang Li, Yunhui Zhang, Deming Gou

Hypertension

DOI

2025

Protein biomarkers in pulmonary arterial hypertension: advances, clinical relevance, and translational challenges

Yanqin Niu, Jinglin Tian, Steeve Provencher, Sébastien Bonnet, Olivier Boucherat, François Potus, Deming Gou

Journal of Translational Medicine

DOI

2025

Diagnostic and prognostic potential of cell-free RNAs in cerebrospinal fluid and plasma for brain tumors

Jinyong Huang, Jinxia Zhou, Jun Wang, Yonghao Yi, Lu Zhang, Shuyong Qiu, Yuanyan Tan, Qianwen Guo, Feilong Zhao, Xinying Li, Yanqin Niu, Haoyu Li, Changwu Wu, Kang Kang, Qing Liu, Deming Gou

npj Precision Oncology

DOI

2025

Three Circulating miRNAs Related to Non-Small-Cell Lung Cancer Progression: An Integrative Analysis of Their Biological Roles

Yanqin Niu, Gaohui Fu, Sijian Xia, Menglong Li, Lin Qiu, Jun Wang, Kang Kang, Deming Gou

Biology

DOI

2025

Genome-wide characterization of circular RNAs in three rat models of pulmonary hypertension reveals distinct pathological patterns

Gaohui Fu, Lin Qiu, Jun Wang, Shujin Li, Jinglin Tian, Jiayu Wu, Xinyang Lin, Yiheng Zhu, Zixin Liu, Lingjie Luo, Ku Wang, Feilong Zhao, Jiahao Kuang, Su‐Qing Liang, Shiran Liang, Yuqing Guo, Yu-Ping Hong, Yonghao Yi, Jinyong Huang, Yanqin Niu, Kang Kang, Deming Gou

BMC Genomics

DOI

2024

lncRNA VELRP Modulates Pulmonary Arterial Smooth Muscle Cell Proliferation and Promotes Vascular Remodeling in Pulmonary Hypertension

Cuilian Liu, Jidong Chen, Xingtao Huang, Qinyi Xia, Lei Yang, Jiao Guo, Jinglin Tian, Jun Wang, Yanqin Niu, Li Li, Deming Gou

Arteriosclerosis Thrombosis and Vascular Biology

DOI

2024

Comprehensive circular RNA profiling provides insight into colorectal cancer pathogenesis and reveals diagnostically relevant biomarkers

Shujin Li, Jun Wang, Lin Qiu, Gaohui Fu, Yang Li, Qiang Su, Yiheng Zhu, Feilong Zhao, Jinglin Tian, Jinyong Huang, Yanqin Niu, Kang Kang, Deming Gou

Clinical and Translational Medicine

DOI

2024

Enhancing RNA-seq bias mitigation with the Gaussian self-benchmarking framework: towards unbiased sequencing data

Qiang Su, Yi Long, Deming Gou, Junmin Quan, Qizhou Lian

BMC Genomics

DOI

2024

Enhancing RNA-seq analysis by addressing all co-existing biases using a self-benchmarking approach with 2D structural insights

Qiang Su, Yi Long, Deming Gou, Junmin Quan, Qizhou Lian

Briefings in Bioinformatics

DOI

2024

Exploring the Spectrum of Long Non-Coding RNA CARMN in Physiological and Pathological Contexts

Hui Li, Chuannan Sun, Bin Luo, Chuzhi Zhan, Weitao Li, Lu Deng, Kang Kang, Deming Gou

Biomolecules

DOI

2024

N6-methyladenosine-driven miR-143/145-KLF4 circuit orchestrates the phenotypic switch of pulmonary artery smooth muscle cells

Kang Kang, Chuannan Sun, Hui Li, Xiaojia Liu, Jingyuan Deng, Silei Chen, Le Zeng, Jiahao Chen, Xinyi Liu, Jiahao Kuang, Jingjing Xiang, Jingqian Cheng, Xiaoyun Liao, Mujin Lin, Xingshi Zhang, Chuzhi Zhan, Sisi Liu, Jun Wang, Yanqin Niu, Cuilian Liu, Cai Liang, Jinsheng Zhu, Shuxin Liang, Haiyang Tang, Deming Gou

Cellular and Molecular Life Sciences

DOI

2024

N6-methyladenosine modification of KLF2 may contribute to endothelial-to-mesenchymal transition in pulmonary hypertension

Kang Kang, Jingjing Xiang, Xingshi Zhang, Yuting Xie, Mengting Zhou, Le Zeng, Junhao Zhuang, Jiahao Kuang, Yuanyuan Lin, Bozhe Hu, Qianmin Xiong, Qing Yin, Qiang Su, Xiaoyun Liao, Jun Wang, Yanqin Niu, Cuilian Liu, Jinglin Tian, Deming Gou

Cellular & Molecular Biology Letters

DOI

2024

Comprehensive characterization of small noncoding RNA profiles in hypoxia-induced pulmonary hypertension (HPH) rat tissues

Jun Wang, Jiahao Kuang, Shasha Zhang, Zixin Liu, Qianwen Guo, Shujin Li, Lin Qiu, Gaohui Fu, Xinyang Lin, Jiayu Wu, Jinglin Tian, Jinyong Huang, Yanqin Niu, Kang Kang, Yunhui Zhang, Deming Gou

iScience

DOI

2024

Endothelium-specific SIRT7 targeting ameliorates pulmonary hypertension through Krüpple-like factor 4 deacetylation

Jin Zhang, Chenzhong Xu, Xiaolong Tang, Shimin Sun, Si-Qi Liu, Langmei Yang, Yuqin Chen, Qifeng Yang, Tong‐You Wade Wei, Xiaojing Wu, Jian Wang, Chen Wang, Xiaosong Yan, Lei Yang, Yanqin Niu, Deming Gou, John Y J Shyy, Baohua Liu

Cardiovascular Research

DOI

2024

Terminal modifications independent cell-free RNA sequencing enables sensitive early cancer detection and classification

Jun Wang, Jinyong Huang, Yunlong Hu, Qianwen Guo, Shasha Zhang, Jinglin Tian, Yanqin Niu, Ling Ji, Yuzhong Xu, Peijun Tang, HE Ya-qin, Yuna Wang, Shuya Zhang, Hao Yang, Kang Kang, Xinchun Chen, Xinying Li, Ming Yuan Yang, Deming Gou

Nature Communications

DOI

2023

Identification and Validation of Genes Exhibiting Dynamic Alterations in Response to Bleomycin-Induced Pulmonary Fibrosis

Deng‐Yuan Li, Jun Wang, Jie Zeng, Shujin Li, Danxiong Sun, Lin Qiu, Zhen-Ming Huang, Ku Wang, Gaohui Fu, Deming Gou, Yunhui Zhang

Molecular Biotechnology

DOI

2023

Critical view on oligo(dT)-based RNA-seq: bias arising, modeling, and mitigating

Qiang Su, Jun Wang, Kang Kang, Yanqin Niu, Shujin Li, Deming Gou

Genetics

DOI

2023

CLT-seq as a universal homopolymer-sequencing concept reveals poly(A)-tail-tuned ncRNA regulation

Qiang Su, Yi Long, Jun Wang, Deming Gou

Briefings in Bioinformatics

DOI

2023

The protective role of EP300 in monocrotaline-induced pulmonary hypertension

Lei Yang, Jinglin Tian, Jun Wang, Jie Zeng, Ting Wang, Boya Lin, John Linneman, Li Li, Yanqin Niu, Deming Gou, Yunhui Zhang

Frontiers in Cardiovascular Medicine

DOI

2023

Gut Microbiota and Metabolome Changes in Three Pulmonary Hypertension Rat Models

Lingjie Luo, Haoyang Yin, Deming Gou

Microorganisms

DOI

2022

糖尿病鼠骨骼肌萎缩相关环状RNA的研究

杨雷，王筠，邓芳，许特，苟德明，周威，胡章立，邹湘辉

《深圳大学学报(理工版)》

2022

MicroRNAs in Pulmonary Hypertension, from Pathogenesis to Diagnosis and Treatment

Junhua Xu, John Linneman, Yanfeng Zhong, Haoyang Yin, Qinyi Xia, Kang Kang, Deming Gou

Biomolecules

DOI

2022

Decoding ceRNA regulatory network in the pulmonary artery of hypoxia-induced pulmonary hypertension (HPH) rat model

Jun Wang, Yanqin Niu, Lingjie Luo, Zefeng Lu, Qinghua Chen, Shasha Zhang, Qianwen Guo, Li Li, Deming Gou

Cell & Bioscience

DOI

2022

LncPTSR Triggers Vascular Remodeling in Pulmonary Hypertension by Regulating [Ca2+]i in Pulmonary Arterial Smooth Muscle Cells

Liyu Deng, Jidong Chen, Bin Chen, Ting Wang, Lei Yang, Jing Liao, Junbo Yi, Yuqin Chen, Jian Wang, John Linneman, Yanqin Niu, Deming Gou

American Journal of Respiratory Cell and Molecular Biology

DOI

2022

Integrative Modeling of Multiomics Data for Predicting Tumor Mutation Burden in Patients with Lung Cancer

Jun Wang, Peng Chen, Ming‐Yang Su, Guocheng Zhong, Shasha Zhang, Deming Gou

BioMed Research International

DOI

2021

MSCs Therapy Reverse the Gut Microbiota in Hypoxia-Induced Pulmonary Hypertension Mice

Lingjie Luo, Qinhua Chen, Lei Yang, Zhenxia Zhang, Jihong Xu, Deming Gou

Frontiers in Physiology

DOI

2020

PDGF/MEK/ERK axis represses Ca2+clearance via decreasing the abundance of plasma membrane Ca2+pump PMCA4 in pulmonary arterial smooth muscle cells

Liyu Deng, Jidong Chen, Ting Wang, Bin Chen, Lei Yang, Jing Liao, Yuqin Chen, Jian Wang, Haiyang Tang, Junbo Yi, Kang Kang, Li Li, Deming Gou

American Journal of Physiology-Cell Physiology

DOI

2020

Circulating microRNA profiles based on direct S‐Poly(T)Plus assay for detection of coronary heart disease

Ming‐Yang Su, Yanqin Niu, Quanjin Dang, Junle Qu, Daling Zhu, Zhongren Tang, Deming Gou

Journal of Cellular and Molecular Medicine

DOI

2020

Pathobiology of pulmonary artery hypertension: role of long non-coding RNAs

Kashif Rafiq Zahid, Umar Raza, Jidong Chen, Usha J Raj, Deming Gou

Cardiovascular Research

DOI

2019

Direct S-Poly(T) Plus assay in quantification of microRNAs without RNA extraction and its implications in colorectal cancer biomarker studies

Yanqin Niu, Sijian Xia, Ming‐Yang Su, Quanjin Dang, Kang Kang, Li Li, Deming Gou

Journal of Translational Medicine

DOI

2018

Circulating Plasma miRNAs as Potential Biomarkers of Non–Small Cell Lung Cancer Obtained by High-Throughput Real-Time PCR Profiling

Yanqin Niu, Ming‐Yang Su, Yike Wu, Liwu Fu, Kang Kang, Qing Li, Li Li, Gang Hui, Furong Li, Deming Gou

Cancer Epidemiology Biomarkers & Prevention

DOI

2018

PDGFBB promotes proliferation and migration via regulating miR-1181/STAT3 axis in human pulmonary arterial smooth muscle cells

Zhengjiang Qian, Yanjiao Li, Haiyang Yang, Jidong Chen, Xiang Li, Deming Gou

American Journal of Physiology-Lung Cellular and Molecular Physiology

DOI

2018

MiR-125a-5p ameliorates monocrotaline-induced pulmonary arterial hypertension by targeting the TGF-β1 and IL-6/STAT3 signaling pathways

Zongye Cai, Jian Li, Qi Zhuang, Xueming Zhang, Ancai Yuan, Lan Shen, Kang Kang, Bo Qu, Yuanjia Tang, Jun Pu, Deming Gou, Jieyan Shen

Experimental & Molecular Medicine

DOI

2018

Phosphatidylinositol 3‐Kinase–DNA Methyltransferase 1–miR‐1281–Histone Deacetylase 4 Regulatory Axis Mediates Platelet‐Derived Growth Factor–Induced Proliferation and Migration of Pulmonary Artery Smooth Muscle Cells

Yanjiao Li, Li Li, Zhengjiang Qian, Boya Lin, Jidong Chen, Yixuan Luo, Junle Qu, J. Usha Raj, Deming Gou

Journal of the American Heart Association

DOI

2017

miRNA通过PPAR和AMPK/SREBPs信号通路调控脂质代谢

马柳安，邱惠玲，李荔，苟德明

《生命的化学》

DOI

2017

miRNA调控成肌分化的研究进展

汤志雄，苟德明

《中国生物工程杂志》

2017

The Long Noncoding RNA LnRPT Is Regulated by PDGF-BB and Modulates the Proliferation of Pulmonary Artery Smooth Muscle Cells

Jidong Chen, Jiao Guo, Xiaolei Cui, Yan Dai, Zhixiong Tang, Junle Qu, J. Usha Raj, Qinghua Hu, Deming Gou

American Journal of Respiratory Cell and Molecular Biology

DOI

2017

MiR-339 inhibits proliferation of pulmonary artery smooth muscle cell by targeting FGF signaling

Jidong Chen, Xiaolei Cui, Li Li, Junle Qu, J. Usha Raj, Deming Gou

Physiological Reports

DOI

2017

miR-4632 mediates PDGF-BB-induced proliferation and antiapoptosis of human pulmonary artery smooth muscle cells via targeting cJUN

Zhengjiang Qian, Yanjiao Li, Jidong Chen, Xiang Li, Deming Gou

American Journal of Physiology-Cell Physiology

DOI

2016

Identification of reference genes for circulating microRNA analysis in colorectal cancer

Yanqin Niu, Yike Wu, Jinyong Huang, Qing Li, Kang Kang, Junle Qu, Furong Li, Deming Gou

Scientific Reports

DOI

2016

Multi-omics analysis reveals regulators of the response to PDGF-BB treatment in pulmonary artery smooth muscle cells

Jidong Chen, Xiaolei Cui, Zhengjiang Qian, Yanjiao Li, Kang Kang, Junle Qu, Li Li, Deming Gou

BMC Genomics

DOI

2016

MiR-328 targeting PIM-1 inhibits proliferation and migration of pulmonary arterial smooth muscle cells in PDGFBB signaling pathway

Zhengjiang Qian, Limin Zhang, Jidong Chen, Yanjiao Li, Kang Kang, Junle Qu, Zhiwei Wang, Yujia Zhai, Li Li, Deming Gou

Oncotarget

DOI

2016

MicroRNA-223 Attenuates Hypoxia-induced Vascular Remodeling by Targeting RhoB/MLC2 in Pulmonary Arterial Smooth Muscle Cells

Yan Zeng, Xiaoying Zhang, Kang Kang, Jidong Chen, Zhiqin Wu, Jinyong Huang, Wenju Lu, Yuqin Chen, Jie Zhang, Zhiwei Wang, Yujia Zhai, Junle Qu, Ramaswamy Ramchandran, J. Usha Raj, Jian Wang, Deming Gou

Scientific Reports

DOI

2015

An improved method for detecting circulating microRNAs with S-Poly(T) Plus real-time PCR

Yanqin Niu, Limin Zhang, Huiling Qiu, Yike Wu, Zhiwei Wang, Yujia Zai, Lin Liu, Junle Qu, Kang Kang, Deming Gou

Scientific Reports

DOI

2015

Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells

Yan Zeng, Hongtao Liu, Kang Kang, Zhiwei Wang, Gang Hui, Xiaoying Zhang, Jiasheng Zhong, Wenda Peng, Ramaswamy Ramchandran, J. Usha Raj, Deming Gou

Scientific Reports

DOI

2015

Loss of MicroRNA-17∼92 in Smooth Muscle Cells Attenuates Experimental Pulmonary Hypertension via Induction of PDZ and LIM Domain 5

Tianji Chen, Guofei Zhou, Qiyuan Zhou, Haiyang Tang, Joyce Christina F. Ibe, Hongqiang Cheng, Deming Gou, Ju Chen, Jason X.‐J. Yuan, J. Usha Raj

American Journal of Respiratory and Critical Care Medicine

DOI

2014

缺氧诱导因子1调控缺氧性肺动脉高压的研究进展

刘洪涛，曾艳，苟德明

《中华高血压杂志(中英文)》

2014

microRNA在缺氧性肺高压中的功能研究

张小英，苟德明

《老年医学与保健》

2014

MicroRNA-206 regulates surfactant secretion by targeting VAMP-2

Honghao Zhang, Yujie Guo, Amarjit Mishra, Deming Gou, N. Chintagari, Lin Liu

FEBS Letters

DOI

2014

MiR‐20a regulates the PRKG1 gene by targeting its coding region in pulmonary arterial smooth muscle cells

Yan Zeng, Yanping Pan, Hongtai Liu, Kang Kang, Yike Wu, Gang Hui, Wenda Peng, Ramaswamy Ramchandran, J. Usha Raj, Deming Gou

FEBS Letters

DOI

2013

microRNAs与心血管疾病的研究进展

彭晓，王志伟，苟德明

《中华临床医师杂志(电子版)》

2013

MicroRNA-124 Suppresses the Transactivation of Nuclear Factor of Activated T Cells by Targeting Multiple Genes and Inhibits the Proliferation of Pulmonary Artery Smooth Muscle Cells

Kang Kang, Xiao Peng, Xiaoying Zhang, Yuna Wang, Lishu Zhang, Li Gao, Tingting Weng, Honghao Zhang, Ramaswamy Ramchandran, J. Usha Raj, Deming Gou, Lin Liu

Journal of Biological Chemistry

DOI

2012

A Novel Real-Time PCR Assay of microRNAs Using S-Poly(T), a Specific Oligo(dT) Reverse Transcription Primer with Excellent Sensitivity and Specificity

Kang Kang, Xiaoying Zhang, Hongtao Liu, Zhiwei Wang, Jiasheng Zhong, Zhenting Huang, Xiao Peng, Yan Zeng, Yuna Wang, Yi Yang, Jun Luo, Deming Gou

PLoS ONE

DOI

2012

miR-210 has an antiapoptotic effect in pulmonary artery smooth muscle cells during hypoxia

Deming Gou, Ramaswamy Ramchandran, Xiao Peng, Lijun Yao, Kang Kang, Joy Sarkar, Zhixin Wang, Goufei Zhou, J. Usha Raj

American Journal of Physiology-Lung Cellular and Molecular Physiology

DOI

2012

Identification of circulating miRNA biomarkers based on global quantitative real-time PCR profiling

Kang Kang, Xiao Peng, Jun Luo, Deming Gou

Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology

DOI

2009

MiR‐21 plays a Role in Smooth Muscle Cell Proliferation induced by Hypoxia

Joy Sarkar, Prasanna Turaka, Deming Gou, R. Ramchandran, Guo-Fei Zhou, A. Raghavan, U. Raj

DOI

2009

MicroRNA‐375 Regulates Alveolar Epithelial Cell Trans‐Differentiation through the Wnt/β‐catenin Pathway

Yang Wang, M. Bhaskaran, Honghao Zhang, Deming Gou, Yujie Guo, Narendranath Reddy Chintagari, Lin Liu

DOI

2009

MicroRNA-127 modulates fetal lung development.

M. Bhaskaran, Yang Wang, Honghao Zhang, Tingting Weng, P. Baviskar, Yujie Guo, Deming Gou, Lin Liu

Physiological Genomics

DOI

2009

MicroRNA-375 inhibits lung surfactant secretion by altering cytoskeleton reorganization

Honghao Zhang, Amarjit Mishra, N. Chintagari, Deming Gou, Lin Liu

IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology

DOI

2009

Prolonged Activation of P2X7R Leads to Alveolar Epithelial Type I Cell Death by Suppressing Wnt/beta‐catenin Pathway

Yujie Guo, Amarjit Mishra, Tingting Weng, Yang Wang, Deming Gou, Lin Liu

DOI

2009

The regulation of NFAT pathway by microRNAs

Deming Gou, Tingting Weng, Honghao Zhang, Li Gao, Lisui Zhang, Lin Liu

DOI

2009

Pleiotrophin Regulates Lung Epithelial Cell Proliferation and Differentiation during Fetal Lung Development via β-Catenin and Dlk1*

Tingting Weng, Li Gao, M. Bhaskaran, Yujie Guo, Deming Gou, Jeyaparthasarathy Narayanaperumal, N. Chintagari, Ke-Xiong Zhang, Lin Liu

Journal of Biological Chemistry

DOI

2008

Knockdown of flotillin-2 inhibits lung surfactant secretion by alveolar type II cells

N. Chintagari, Deming Gou, Lin Liu

Cell Research

DOI

2008

Annexin A2 Interactions with Rab14 in Alveolar Type II Cells*

Deming Gou, Amarjit Mishra, Tingting Weng, L. Su, N. Chintagari, Zhi-Xin Wang, Honghao Zhang, Li Gao, Pengcheng Wang, Heidi M. Stricker, Lin Liu

Journal of Biological Chemistry

DOI

2007

Identification of rat lung-specific microRNAs by micoRNA microarray: valuable discoveries for the facilitation of lung research

Yang Wang, Tingting Weng, Deming Gou, Zhongming Chen, N. Chintagari, Lin Liu

BMC Genomics

DOI

2007

Annexin A2 and its associated genes in alveolar epithelial type II cells

Deming Gou, Pengcheng Wang, Honghao Zhang, Tingting Weng, Li Gao, Yang Wang, Zhi-Xin Wang, Lin Liu

DOI

2007

Physical and functional interactions of SNAP-23 with annexin A2.

Pengcheng Wang, N. Chintagari, Deming Gou, L. Su, Lin Liu

American Journal of Respiratory Cell and Molecular Biology

DOI

2007

Pleiotrophin Regulates Alveolar Epithelial Cell Differentiation During Fetal Lung Development

Tingting Weng, Li Gao, Ke-Xiong Zhang, M. Bhaskaran, Deming Gou, Lin Liu

DOI

2007

MicroRNA: past and present.

Yang Wang, Heidi M. Stricker, Deming Gou, Lin Liu

Frontiers in Bioscience

DOI

2007

A novel approach for the construction of multiple shRNA expression vectors

Deming Gou, Tingting Weng, Yang Wang, Zhi-Xin Wang, Honghao Zhang, Li Gao, Zhongming Chen, Pengcheng Wang, Lin Liu

Journal of Gene Medicine

DOI

2007

Primer extension-based method for the generation of a siRNA/miRNA expression vector.

Deming Gou, Honghao Zhang, P. Baviskar, Lin Liu

Physiological Genomics

DOI

2007

MicroRNA Microarray Analysis of Rat Lung‐specific MicroRNAs

Yang Wang, Tingting Weng, Deming Gou, Zhongming Chen, Narendranath Reddy Chintagari, Lin Liu

DOI

2006

The trans‐differentiation of alveolar epithelial type II cells to type I cells involves autocrine signaling through Smad‐mediated TGF beta1 pathway

M. Bhaskaran, N. Kolliputi, Yang Wang, Deming Gou, N. Chintagari, Lin Liu

DOI

2006

A novel fluid transport pathway in adult rat alveolar epithelial type II cells

Nili Jin, N. Kolliputi, Deming Gou, Tingting Weng, Lin Liu

DOI

2006

A Novel Function of Ionotropic γ-Aminobutyric Acid Receptors Involving Alveolar Fluid Homeostasis*

Nili Jin, Narasiah Kolliputi, Deming Gou, Tingting Weng, Lin Liu

Journal of Biological Chemistry

DOI

2006

GABAA receptors play a role in fluid secretion in rat fetal lung

N. Kolliputi, Nili Jin, Deming Gou, Tingting Weng, Yang Wang, Lin Liu

DOI

2006

Trans-differentiation of Alveolar Epithelial Type II Cells to Type I Cells Involves Autocrine Signaling by Transforming Growth Factor β1 through the Smad Pathway*

M. Bhaskaran, N. Kolliputi, Yang Wang, Deming Gou, N. Chintagari, Lin Liu

Journal of Biological Chemistry

DOI

2004

Syntaxin 2 and SNAP-23 are required for regulated surfactant secretion.

Barack O. Abonyo, Deming Gou, Pengcheng Wang, T. Narasaraju, Zhixin Wang, Lin Liu

Biochemistry

DOI

2004

Gene silencing in alveolar type II cells using cell-specific promoter in vitro and in vivo.

Deming Gou, T. Narasaraju, N. Chintagari, Nili Jin, Pengcheng Wang, Lin Liu

Nucleic Acids Research

DOI

2003

Gene silencing in mammalian cells by PCR‐based short hairpin RNA

Deming Gou, Nili Jin, Lin Liu

FEBS Letters

DOI

2003

Protein nitration in rat lungs during hyperoxia exposure: a possible role of myeloperoxidase.

T. Narasaraju, Nili Jin, Chintagari R Narendranath, Zhongming Chen, Deming Gou, Lin Liu

American Journal of Physiology - Lung cellular and Molecular Physiology

DOI

精选作品

期刊论文

Metabolomic and lipidomic signatures associated with clinical improvement after balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension

Integrative profiling of multi-modal plasma cfRNA signatures enables detection and prognostic risk stratification in breast cancer

Omaveloxolone Driven NRF2 Activation as a Novel Therapeutic Strategy for Pulmonary Hypertension

Plasma miRNA signature for the diagnosis of pulmonary tuberculosis in symptomatic patients

THBS4 Regulates Pulmonary Hypertension via TGF-β/SMAD2 Signaling

Protein biomarkers in pulmonary arterial hypertension: advances, clinical relevance, and translational challenges

Diagnostic and prognostic potential of cell-free RNAs in cerebrospinal fluid and plasma for brain tumors

Three Circulating miRNAs Related to Non-Small-Cell Lung Cancer Progression: An Integrative Analysis of Their Biological Roles

Genome-wide characterization of circular RNAs in three rat models of pulmonary hypertension reveals distinct pathological patterns

lncRNA VELRP Modulates Pulmonary Arterial Smooth Muscle Cell Proliferation and Promotes Vascular Remodeling in Pulmonary Hypertension

Comprehensive circular RNA profiling provides insight into colorectal cancer pathogenesis and reveals diagnostically relevant biomarkers

Enhancing RNA-seq bias mitigation with the Gaussian self-benchmarking framework: towards unbiased sequencing data

Enhancing RNA-seq analysis by addressing all co-existing biases using a self-benchmarking approach with 2D structural insights

Exploring the Spectrum of Long Non-Coding RNA CARMN in Physiological and Pathological Contexts

N6-methyladenosine-driven miR-143/145-KLF4 circuit orchestrates the phenotypic switch of pulmonary artery smooth muscle cells

N6-methyladenosine modification of KLF2 may contribute to endothelial-to-mesenchymal transition in pulmonary hypertension

Comprehensive characterization of small noncoding RNA profiles in hypoxia-induced pulmonary hypertension (HPH) rat tissues

Endothelium-specific SIRT7 targeting ameliorates pulmonary hypertension through Krüpple-like factor 4 deacetylation

Terminal modifications independent cell-free RNA sequencing enables sensitive early cancer detection and classification

Identification and Validation of Genes Exhibiting Dynamic Alterations in Response to Bleomycin-Induced Pulmonary Fibrosis

Critical view on oligo(dT)-based RNA-seq: bias arising, modeling, and mitigating

CLT-seq as a universal homopolymer-sequencing concept reveals poly(A)-tail-tuned ncRNA regulation

The protective role of EP300 in monocrotaline-induced pulmonary hypertension

Gut Microbiota and Metabolome Changes in Three Pulmonary Hypertension Rat Models

糖尿病鼠骨骼肌萎缩相关环状RNA的研究

MicroRNAs in Pulmonary Hypertension, from Pathogenesis to Diagnosis and Treatment

Decoding ceRNA regulatory network in the pulmonary artery of hypoxia-induced pulmonary hypertension (HPH) rat model

LncPTSR Triggers Vascular Remodeling in Pulmonary Hypertension by Regulating [Ca2+]i in Pulmonary Arterial Smooth Muscle Cells

Integrative Modeling of Multiomics Data for Predicting Tumor Mutation Burden in Patients with Lung Cancer

MSCs Therapy Reverse the Gut Microbiota in Hypoxia-Induced Pulmonary Hypertension Mice

PDGF/MEK/ERK axis represses Ca2+clearance via decreasing the abundance of plasma membrane Ca2+pump PMCA4 in pulmonary arterial smooth muscle cells

Circulating microRNA profiles based on direct S‐Poly(T)Plus assay for detection of coronary heart disease

Pathobiology of pulmonary artery hypertension: role of long non-coding RNAs

Direct S-Poly(T) Plus assay in quantification of microRNAs without RNA extraction and its implications in colorectal cancer biomarker studies

Circulating Plasma miRNAs as Potential Biomarkers of Non–Small Cell Lung Cancer Obtained by High-Throughput Real-Time PCR Profiling

PDGFBB promotes proliferation and migration via regulating miR-1181/STAT3 axis in human pulmonary arterial smooth muscle cells

MiR-125a-5p ameliorates monocrotaline-induced pulmonary arterial hypertension by targeting the TGF-β1 and IL-6/STAT3 signaling pathways

Phosphatidylinositol 3‐Kinase–DNA Methyltransferase 1–miR‐1281–Histone Deacetylase 4 Regulatory Axis Mediates Platelet‐Derived Growth Factor–Induced Proliferation and Migration of Pulmonary Artery Smooth Muscle Cells

miRNA通过PPAR和AMPK/SREBPs信号通路调控脂质代谢

miRNA调控成肌分化的研究进展

The Long Noncoding RNA LnRPT Is Regulated by PDGF-BB and Modulates the Proliferation of Pulmonary Artery Smooth Muscle Cells

MiR-339 inhibits proliferation of pulmonary artery smooth muscle cell by targeting FGF signaling

miR-4632 mediates PDGF-BB-induced proliferation and antiapoptosis of human pulmonary artery smooth muscle cells via targeting cJUN

Identification of reference genes for circulating microRNA analysis in colorectal cancer

Multi-omics analysis reveals regulators of the response to PDGF-BB treatment in pulmonary artery smooth muscle cells

MiR-328 targeting PIM-1 inhibits proliferation and migration of pulmonary arterial smooth muscle cells in PDGFBB signaling pathway

MicroRNA-223 Attenuates Hypoxia-induced Vascular Remodeling by Targeting RhoB/MLC2 in Pulmonary Arterial Smooth Muscle Cells

An improved method for detecting circulating microRNAs with S-Poly(T) Plus real-time PCR

Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells

Loss of MicroRNA-17∼92 in Smooth Muscle Cells Attenuates Experimental Pulmonary Hypertension via Induction of PDZ and LIM Domain 5

缺氧诱导因子1调控缺氧性肺动脉高压的研究进展

microRNA在缺氧性肺高压中的功能研究

MicroRNA-206 regulates surfactant secretion by targeting VAMP-2

MiR‐20a regulates the PRKG1 gene by targeting its coding region in pulmonary arterial smooth muscle cells

microRNAs与心血管疾病的研究进展

MicroRNA-124 Suppresses the Transactivation of Nuclear Factor of Activated T Cells by Targeting Multiple Genes and Inhibits the Proliferation of Pulmonary Artery Smooth Muscle Cells

A Novel Real-Time PCR Assay of microRNAs Using S-Poly(T), a Specific Oligo(dT) Reverse Transcription Primer with Excellent Sensitivity and Specificity

miR-210 has an antiapoptotic effect in pulmonary artery smooth muscle cells during hypoxia

Identification of circulating miRNA biomarkers based on global quantitative real-time PCR profiling

MiR‐21 plays a Role in Smooth Muscle Cell Proliferation induced by Hypoxia

MicroRNA‐375 Regulates Alveolar Epithelial Cell Trans‐Differentiation through the Wnt/β‐catenin Pathway

MicroRNA-127 modulates fetal lung development.

MicroRNA-375 inhibits lung surfactant secretion by altering cytoskeleton reorganization

Prolonged Activation of P2X7R Leads to Alveolar Epithelial Type I Cell Death by Suppressing Wnt/beta‐catenin Pathway

The regulation of NFAT pathway by microRNAs

Pleiotrophin Regulates Lung Epithelial Cell Proliferation and Differentiation during Fetal Lung Development via β-Catenin and Dlk1*

Knockdown of flotillin-2 inhibits lung surfactant secretion by alveolar type II cells

Annexin A2 Interactions with Rab14 in Alveolar Type II Cells*

Identification of rat lung-specific microRNAs by micoRNA microarray: valuable discoveries for the facilitation of lung research

Annexin A2 and its associated genes in alveolar epithelial type II cells

Physical and functional interactions of SNAP-23 with annexin A2.

Pleiotrophin Regulates Alveolar Epithelial Cell Differentiation During Fetal Lung Development

MicroRNA: past and present.

A novel approach for the construction of multiple shRNA expression vectors

Primer extension-based method for the generation of a siRNA/miRNA expression vector.

MicroRNA Microarray Analysis of Rat Lung‐specific MicroRNAs

The trans‐differentiation of alveolar epithelial type II cells to type I cells involves autocrine signaling through Smad‐mediated TGF beta1 pathway

A novel fluid transport pathway in adult rat alveolar epithelial type II cells