张宏娜｜青岛大学｜学者主页

2026

Organophosphorus flame retardants (OPFRs) in lithium-ion batteries: Classification, physicochemical properties, environmental behavior, human exposure and toxicity.

Hao-zheng Li, Jun-Tong Wei, Shanfa Yu, Hongna Zhang, Yu-Xin Zheng

Journal of Hazardous Materials

DOI

2026

Metabolic alterations in lithium iron phosphate exposed workers and their mediation role in lung function decline: A cohort study.

Pengwei Ji, Jingwen Zheng, Haozheng Li, Wei Gao, Yong-Feng Lin, Jun-Tong Wei, Shanfa Yu, Hongna Zhang, Yuxin Zheng

Ecotoxicology and Environmental Safety

DOI

2026

Mechanism of diesel exhaust-induced thyroid inflammatory injury via the AHR-NLRP3 signaling pathway.

Hu Hao, Sisi Qin, Zhi-Cheng Zhang, Xiaoyin Guo, Q. Song, Hongna Zhang, Cheng-Xiang Cui, Shoujie Dai, Meng-Hui Jiang, Jin-Mei Piao

Ecotoxicology and Environmental Safety

DOI

2026

Mechanistic insights into triclocarban-induced skin barrier disruption via integrating imaging localization, multi-omics, and network toxicology.

Jingwen Zheng, Run Guo, Rong-Jie Zhang, Xinyu Liu, R. Guo, Hao-Zheng Li, Jun-Tong Wei, Yu-Xin Zheng, Hongna Zhang

Environmental Pollution

DOI

2026

Live Airway Prevotella Attenuated Diesel Exhaust-Induced Lung Injury and Neutrophil Activation via Bacterial Extracellular Vesicles

Bojia Wang, Li-Hua Yang, Jiahua Cai, Qixiao Jiang, Hongna Zhang, Jin-Mei Piao, Weizhong Han, Yu-Xin Zheng, Meng-Hui Jiang

Environmental Health

DOI

2026

High-Resolution Mass Spectrometry-Based Suspect and Nontarget Screening of Organophosphate/Organofluorophosphate Esters in Spent Ternary Lithium-Ion Power Batteries.

Cuili Zhang, Hongna Zhang, Peng-Fei Wu, Bing Wang, Yating Xiao, Xin-Xin Gu, Yongbiao Wan, Ming Li, Yong-Feng Lin, Wei Gao, Xiao-Ran Wei, Jun-Tong Wei, Yu-Xin Zheng

Environmental Science and Technology

DOI

2025

Diesel exhaust induces hepatic steatosis by activating the aryl hydrocarbon receptor/CD36 pathway.

Q. Song, Xueying Zhang, Yanting Li, Zixuan Liang, Ao Han, Xiao-Ran Wei, Xiaowen Tang, Jun-Tong Wei, Wei Han, Shanfa Yu, Hongna Zhang, Yu-Xin Zheng

Journal of Hazardous Materials

DOI

2025

Comprehensive metabolomics reveals glycolipid metabolic disturbance and potential biomarkers in Chinese diesel exhaust-exposed workers: A cohort study.

Yan-Song Li, Yanting Li, Chengchen Hu, Run Guo, Wenli Bai, Long-Sheng Chen, Shanfa Yu, Jun-Tong Wei, Hongna Zhang, Yu-Xin Zheng

Ecotoxicology and Environmental Safety

DOI

2025

Triclocarban Disrupts Hepatic Lipid Homeostasis and Promotes Endoplasmic Reticulum Stress in Mice: A Multiomics Investigation.

Q. Song, Rong Zhang, Xinyu Liu, X. Ji, Ao Han, Fang He, Ruyun Ding, Hongna Zhang

Chemical Research in Toxicology

DOI

2024

Integrated multi-omics approaches reveal the neurotoxicity of triclocarban in mouse brain.

Q. Song, Chengchen Hu, Xueying Zhang, Pengwei Ji, Yan-Song Li, Hanyong Peng, Yu-Xin Zheng, Hongna Zhang

Environment International

DOI

2024

Exploring Prenatal Exposure to Halogenated Compounds and Its Relationship with Birth Outcomes Using Nontarget Analysis.

Huan Lin, Wei Gao, Jingjing Li, Nan Zhao, Hongna Zhang, Jun-Tong Wei, Xiao-Ran Wei, Bing Wang, Yong-Feng Lin, Yu-Xin Zheng

Environmental Science and Technology

DOI

2024

Mechanism underlying the role of integrin α3β1 in adhesive dysfunction between thyroid cells induced by diesel engine exhaust particles.

Xiaoyin Guo, Siying Tang, Yanting Li, Chaohui Mu, Hongna Zhang, Qixiao Jiang, Meng-Hui Jiang, Weizhong Han, Yu-Xin Zheng, Jin-Mei Piao

Science of the Total Environment

DOI

2024

Competitive-like binding between carbon black and CTNNB1 to ΔNp63 interpreting the abnormal respiratory epithelial repair after injury.

Xiao-Ran Wei, N. Liu, Yawen Feng, Hong-Mei Wang, Weizhong Han, Min Zhuang, Hongna Zhang, Wei Gao, Yong-Feng Lin, Xiao-Wen Tang, Yu-Xin Zheng

Science of the Total Environment

DOI

2023

Long-term percutaneous triclosan exposure induces thyroid damage in mice: Interpretation of toxicity mechanism from metabolic and proteomic perspectives

Yanshan Liang, Leiguang Li, Hongna Zhang, Qingyuan Dai, Guangshan Xie, Bo Lei, Zhu Yang, Zongwei Cai

Journal of Hazardous Materials

DOI

2023

Trimester-specific exposure to triclocarban during pregnancy: Associations with oxidative stress and size at birth.

Hongna Zhang, Qiong Luo, Chengchen Hu, Q. Song, Yanqiu Zhou, Xiuli Su, Yuan-Yuan Li, W. Xia, Yu-Xin Zheng, Shunqing Xu, Zongwei Cai

Science of the Total Environment

DOI

2022

Microbiota-mediated reactivation of triclosan oxidative metabolites in colon tissues

Hongna Zhang, K. Sanidad, Jianan Zhang, Guang-Qiang Wang, Rong Zhang, Chengchen Hu, Yongfeng Lin, T. Haggerty, J. Parsonnet, Yu-Xin Zheng, Guodong Zhang, Zongwei Cai

Journal of Hazardous Materials

DOI

2022

Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract

Jianan Zhang, Morgan E. Walker, K. Sanidad, Hongna Zhang, Yanshan Liang, Ermin Zhao, Katherine Chacón-Vargas, V. Yeliseyev, J. Parsonnet, T. Haggerty, Guang-Qiang Wang, J. B. Simpson, P. Jariwala, Violet V. Beaty, Jun Yang, Haixia Yang, Anand Panigrahy, L. Minter, Daeyoung Kim, J. Gibbons, Lin-Shu Liu, Zheng-Ze Li, Hang Xiao, V. Borlandelli, H. Overkleeft, Erica W. Cloer, Michael B. Major, D. Goldfarb, Zongwei Cai, M. Redinbo, Guodong Zhang

Nature Communications

DOI

2022

Intertidal zone effects on Occurrence, fate and potential risks of microplastics with perspectives under COVID-19 pandemic

Pengfei Wu, Hongna Zhang, Narendra Singh, Yuan-Yuan Tang, Zongwei Cai

Chemical Engineering Journal

DOI

2022

Three-Dimensional Mass Spectrometry Imaging Reveals Distributions of Lipids and the Drug Metabolite Associated with the Enhanced Growth of Colon Cancer Cell Spheroids Treated with Triclosan

Peisi Xie, Hongna Zhang, Pengfei Wu, Yanyan Chen, Zongwei Cai

Analytical Chemistry

DOI

2022

Metabolomics Reveal Nanoplastic-Induced Mitochondrial Damage in Human Liver and Lung Cells

Si-Yi Lin, Hongna Zhang, Chen Wang, X. Su, Yuanyuan Song, Pengfei Wu, Zhu Yang, M. Wong, Zongwei Cai, Chun-Miao Zheng

Environmental Science and Technology

DOI

2022

Metabolomics and proteomics study reveals the effects of benzo[a]pyrene on the viability and migration of KYSE-150 esophageal cells.

Yuting Shen, Guangshan Xie, Si-Yi Lin, Lin Zhu, Hongna Zhang, Zhu Yang, Zongwei Cai

Science of the Total Environment

DOI

2021

全氟烷基羧酸前体物氟调醇的污染水平与生物转化研究进展

张宏娜，温蓓，张淑贞

《环境化学》

2021

Exposure to ambient fine particulate matter impedes the function of spleen in the mouse metabolism of high-fat diet.

Zhao He, Hongna Zhang, Yuanyuan Song, Zhu Yang, Zongwei Cai

Journal of Hazardous Materials

DOI

2021

Metabolic fate of environmental chemical triclocarban in colon tissues: roles of gut microbiota involved

Guang-Qiang Wang, Hongna Zhang, Jianan Zhang, K. Sanidad, V. Yeliseyev, J. Parsonnet, T. Haggerty, Hai-Xia Yang, L. Ai, Min-Hao Xie, Zongwei Cai, Guodong Zhang

Science of the Total Environment

DOI

2021

Simultaneous determination of triclosan, triclocarban, triclocarban metabolites and byproducts in urine and serum by UHPLC-ESI-MS/MS.

Qiong Luo, Hongna Zhang, Yanqiu Zhou, Ze-Hua Liu, Zongwei Cai

Rapid Communications in Mass Spectrometry

DOI

2021

Sulfinylation on Superoxide Dismutase 1 Cys111: Novel Mechanism for 1‐Nitropyrene to Promote Acute Reactive Oxygen Species Generation

Guangshan Xie, Lin Zhu, Yan-Hao Zhang, Yuanyuan Song, Hongna Zhang, Zhu Yang, Zongwei Cai

Small Structures

DOI

2021

Comprehensive multi-omics approaches reveal the hepatotoxic mechanism of perfluorohexanoic acid (PFHxA) in mice.

Lilong Jiang, Yanjun Hong, Guangshan Xie, Jinghui Zhang, Hongna Zhang, Zongwei Cai

Science of the Total Environment

DOI

2021

Continuous Dermal Exposure to Triclocarban Perturbs the Homeostasis of Liver-Gut Axis in Mice: Insights from Metabolic Interactions and Microbiome Shifts.

Hongna Zhang, Yanshan Liang, Pengfei Wu, Xian-Ru Shi, Guodong Zhang, Zongwei Cai

Environmental Science and Technology

DOI

2020

Triclocarban-induced responses of endogenous and xenobiotic metabolism in human hepatic cells: Toxicity assessment based on nontargeted metabolomics approach.

Hongna Zhang, Yao Lu, Yanshan Liang, Lilong Jiang, Zongwei Cai

Journal of Hazardous Materials

DOI

2020

Frequent occurrence of triclosan hydroxylation in mammals: A combined theoretical and experimental investigation.

Hongna Zhang, K. Sanidad, Lin Zhu, J. Parsonnet, T. Haggerty, Guodong Zhang, Zongwei Cai

Journal of Hazardous Materials

DOI

2020

Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study.

Yanqiu Zhou, Ying Li, Shunqing Xu, Jiaqiang Liao, Hongna Zhang, Jiufeng Li, Yanjun Hong, W. Xia, Zongwei Cai

Journal of Hazardous Materials

DOI

2020

New insights into the cellular mechanism of triclosan-induced dermal toxicity from a combined metabolomic and lipidomic approach.

Yanshan Liang, Hongna Zhang, Zongwei Cai

Science of the Total Environment

DOI

2019

全氟和多氟烷基化合物异构体的分析方法、环境行为和生物效应研究进展

张宏娜，温蓓，张淑贞

《环境化学》

2019

Triclocarban exposure exaggerates spontaneous colonic inflammation in Il-10-/- mice.

Min-Hao Xie, Hongna Zhang, Weicang Wang, Heather L. Sherman, L. Minter, Zongwei Cai, Guodong Zhang

Toxicological Sciences

DOI

2019

Core-Shell Structured Magnetic Covalent Organic Framework Nanocomposites for Triclosan and Triclocarban Adsorption.

Yan-Xia Li, Hongna Zhang, Yi-Ting Chen, Lu Huang, Zian Lin, Zongwei Cai

ACS Applied Materials and Interfaces

DOI

2019

Integration of Metabolomics and Lipidomics Reveals Metabolic Mechanisms of Triclosan-Induced Toxicity in Human Hepatocytes.

Hongna Zhang, Xiaojian Shao, Hong-Zhi Zhao, Xiaona Li, Jun-Tong Wei, Chunxue Yang, Zongwei Cai

Environmental Science and Technology

DOI

2018

大田条件下污泥施用土壤中全氟烷酸化合物的玉米吸收和传输

张宏娜，温蓓，马义兵，胡晓宇，张淑贞

《环境化学》

2018

Formation of dioxins from triclosan with active chlorine: A potential risk assessment

Jian-lin Wu, Fenfen Ji, Hongna Zhang, Chuanqin Hu, Minghung Wong, D. Hu, Zongwei Cai

Journal of Hazardous Materials

DOI

精选作品

期刊论文

Organophosphorus flame retardants (OPFRs) in lithium-ion batteries: Classification, physicochemical properties, environmental behavior, human exposure and toxicity.

Metabolic alterations in lithium iron phosphate exposed workers and their mediation role in lung function decline: A cohort study.

Mechanism of diesel exhaust-induced thyroid inflammatory injury via the AHR-NLRP3 signaling pathway.

Mechanistic insights into triclocarban-induced skin barrier disruption via integrating imaging localization, multi-omics, and network toxicology.

Live Airway Prevotella Attenuated Diesel Exhaust-Induced Lung Injury and Neutrophil Activation via Bacterial Extracellular Vesicles

High-Resolution Mass Spectrometry-Based Suspect and Nontarget Screening of Organophosphate/Organofluorophosphate Esters in Spent Ternary Lithium-Ion Power Batteries.

Diesel exhaust induces hepatic steatosis by activating the aryl hydrocarbon receptor/CD36 pathway.

Comprehensive metabolomics reveals glycolipid metabolic disturbance and potential biomarkers in Chinese diesel exhaust-exposed workers: A cohort study.

Triclocarban Disrupts Hepatic Lipid Homeostasis and Promotes Endoplasmic Reticulum Stress in Mice: A Multiomics Investigation.

Integrated multi-omics approaches reveal the neurotoxicity of triclocarban in mouse brain.

Exploring Prenatal Exposure to Halogenated Compounds and Its Relationship with Birth Outcomes Using Nontarget Analysis.

Mechanism underlying the role of integrin α3β1 in adhesive dysfunction between thyroid cells induced by diesel engine exhaust particles.

Competitive-like binding between carbon black and CTNNB1 to ΔNp63 interpreting the abnormal respiratory epithelial repair after injury.

Long-term percutaneous triclosan exposure induces thyroid damage in mice: Interpretation of toxicity mechanism from metabolic and proteomic perspectives

Trimester-specific exposure to triclocarban during pregnancy: Associations with oxidative stress and size at birth.

Microbiota-mediated reactivation of triclosan oxidative metabolites in colon tissues

Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract

Intertidal zone effects on Occurrence, fate and potential risks of microplastics with perspectives under COVID-19 pandemic

Three-Dimensional Mass Spectrometry Imaging Reveals Distributions of Lipids and the Drug Metabolite Associated with the Enhanced Growth of Colon Cancer Cell Spheroids Treated with Triclosan

Metabolomics Reveal Nanoplastic-Induced Mitochondrial Damage in Human Liver and Lung Cells

Metabolomics and proteomics study reveals the effects of benzo[a]pyrene on the viability and migration of KYSE-150 esophageal cells.

全氟烷基羧酸前体物氟调醇的污染水平与生物转化研究进展

Exposure to ambient fine particulate matter impedes the function of spleen in the mouse metabolism of high-fat diet.

Metabolic fate of environmental chemical triclocarban in colon tissues: roles of gut microbiota involved

Simultaneous determination of triclosan, triclocarban, triclocarban metabolites and byproducts in urine and serum by UHPLC-ESI-MS/MS.

Sulfinylation on Superoxide Dismutase 1 Cys111: Novel Mechanism for 1‐Nitropyrene to Promote Acute Reactive Oxygen Species Generation

Comprehensive multi-omics approaches reveal the hepatotoxic mechanism of perfluorohexanoic acid (PFHxA) in mice.

Continuous Dermal Exposure to Triclocarban Perturbs the Homeostasis of Liver-Gut Axis in Mice: Insights from Metabolic Interactions and Microbiome Shifts.

Triclocarban-induced responses of endogenous and xenobiotic metabolism in human hepatic cells: Toxicity assessment based on nontargeted metabolomics approach.

Frequent occurrence of triclosan hydroxylation in mammals: A combined theoretical and experimental investigation.

Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study.

New insights into the cellular mechanism of triclosan-induced dermal toxicity from a combined metabolomic and lipidomic approach.

全氟和多氟烷基化合物异构体的分析方法、环境行为和生物效应研究进展

Triclocarban exposure exaggerates spontaneous colonic inflammation in Il-10-/- mice.

Core-Shell Structured Magnetic Covalent Organic Framework Nanocomposites for Triclosan and Triclocarban Adsorption.

Integration of Metabolomics and Lipidomics Reveals Metabolic Mechanisms of Triclosan-Induced Toxicity in Human Hepatocytes.

大田条件下污泥施用土壤中全氟烷酸化合物的玉米吸收和传输

Formation of dioxins from triclosan with active chlorine: A potential risk assessment

会议论文

污泥施用土壤中N-乙基全氟辛基磺酰胺乙酸(N-EtFOSAA)的植物吸收、传输及在土壤-植物系统中的降解行为研究

大豆对6:2氟调聚醇的吸收、传输和代谢研究

土壤和植物中氟调聚醇及其降解产物的超高效液相色谱-串联质谱分析方法

用UPLC/MS/MS测定污泥施用土壤和植物中氟调聚醇及其降解产物

研究方向