李桂英｜吉林大学｜学者主页

2026

Corrigendum to "An intrabody targeting PHD2 protects mice against acetaminophen-induced liver injury by attenuating ferroptosis" [Free Radic. Biol. Med. 243 (2026) 260-275].

Zeying Ren, Ying Wang, Cheng Cheng, Yingming Zhang, Yanfei Liu, Yuchong Wei, Zhaoyang Liu, Jingyue Zhang, Zijian Shi, Jiayin Yu, Wanning Hu, Junbo Ye, Jian-Xia Wang, S. Qiu, Guiying Li

Free Radical Biology & Medicine

DOI

2025

Immunofluorescent analysis of exosomes using a microchip filled with transparent antibody-conjugated beads for breast cancer liquid biopsy.

Na Li, Cheng Cheng, Di Wu, Zi-Xuan Song, Bei Wang, Guiying Li, Fang Yang

Analytica Chimica Acta

DOI

2025

The role of rare ginsenosides in the prevention and treatment of liver diseases.

Yingming Zhang, Yanfei Liu, Yuchong Wei, Ze Ren, Ying-Hua Jin, Guiying Li

Journal of Ethnopharmacology

DOI

2025

Small Extracellular Vesicles Detection by Dielectrophoresis-Based Microfluidic Chip Filled with Transparent Antibody-Conjugated Microbeads for Breast Cancer Diagnosis.

Mei Lan, Di Wu, Cheng Cheng, Ze Ren, Si-Yu Chen, Yu-Lai Li, Zi-Xuan Song, Hong-Lin Lu, Jian-Xia Wang, Guiying Li, Fang Yang

Analytical Chemistry

DOI

2025

An Intrabody Targeting PHD2 Protects Mice against Acetaminophen-Induced Liver Injury by Attenuating Ferroptosis.

Ze Ren, Ying Wang, Cheng Cheng, Yingming Zhang, Yanfei Liu, Yuchong Wei, Zhaoyang Liu, Jingyue Zhang, Zijian Shi, Jiayin Yu, Wanning Hu, Junbo Ye, Jian-Xia Wang, S. Qiu, Guiying Li

Free Radical Biology & Medicine

DOI

2024

Small extracellular vesicles detection using dielectrophoresis-based microfluidic chip for diagnosis of breast cancer.

Mei Lan, Ze Ren, Cheng Cheng, Guiying Li, Fang Yang

Biosensors & bioelectronics

DOI

2023

The Regulation of Exosome Generation and Function in Physiological and Pathological Processes

Ying Wang, Tong Xiao, Chaoran Zhao, Guiying Li

International Journal of Molecular Sciences

DOI

2023

The role of TRIM family in metabolic associated fatty liver disease

Jingyue Zhang, Yingming Zhang, Ze Ren, Dong-Mei Yan, Guiying Li

Frontiers in Endocrinology

DOI

2023

A specific anti-cyclin D1 intrabody represses breast cancer cell proliferation by interrupting the cyclin D1–CDK4 interaction

Jialiang Zhao, Yan Wu, Tong Xiao, Cheng Cheng, Tong Zhang, Ziyang Gao, Siyuan Hu, Ze Ren, Xinze Yu, Fang Yang, Guiying Li

Breast Cancer Research and Treatment

DOI

2023

Electrolysis of Bacteria Based on Microfluidic Technology

Jianqiu Zhao, Na Li, Xinyu Zhou, Zihan Yu, Mei Lan, Siyu Chen, Jiajia Miao, Yulai Li, Guiying Li, Fang Yang

Micromachines

DOI

2022

Immunofluorescence analysis of breast cancer biomarkers using antibody-conjugated microbeads embedded in a microfluidic-based liquid biopsy chip

Na Li, Yu Jiang, Tianyi Lv, Guiying Li, Fang Yang

Biosensors and Bioelectronics

DOI

2022

Biochemical Reaction Acceleration by Electrokinetic Mixing in a Microfluidic Chip

Mingzhan Liu, Na Li, Shunyu Cui, Guiying Li, Fang Yang

The Journal of Physical Chemistry Letters

DOI

2022

Clot structure-based physical-matching design of platelet cloaking nano-delivery system facilitates specific arteriovenous thrombolysis

Yujiao Wang, Linwen Lv, Haojun Liang, Wei Ping Liang, Ziteng Chen, Jiacheng Li, Sen Liu, Fan Hu, Junyu Zhu, Qiuyang Liu, Zhijie Wang, Yanan Chang, Juan Li, Min Li, Guiying Li, Kui Chen, Gengmei Xing

Chemical Engineering Journal

DOI

2022

The Role of Exosomes in Inflammatory Diseases and Tumor-Related Inflammation

Yuan Tian, Cheng Cheng, Yuchong Wei, Fang Yang, Guiying Li

Cells

DOI

2021

Expression, purification and characterisation of a human anti-CDK4 single-chain variable fragment antibody

Jialiang Zhao, Jingjing Xu, Tianbin Yang, Xinze Yu, Cheng Cheng, Tong Zhang, Ze Ren, Na Li, Fang Yang, Guiying Li

BMC Biotechnology

DOI

2020

Explore a novel function of human condensins in cellular senescence

Hongzhen Wang, Xin Zhe Liu, Guiying Li

Cell & Bioscience

DOI

2020

Separation of Macrophages Using a Dielectrophoresis-Based Microfluidic Device

Ying Zhang, Shangyu Wang, Jie Chen, Fang Yang, Guiying Li

BioChip Journal

DOI

2020

A Cyclin D1‐Specific Single‐Chain Variable Fragment Antibody that Inhibits HepG2 Cell Growth and Proliferation

Yan Wu, Weiwei Tang, Yuhua Cao, Dazhi Jiang, Liangzhong Zhao, Jialiang Zhao, Ying Zhang, Chengjuan Li, Cheng Cheng, Shuai Wang, Fang Yang, Xun Zhu, Guiying Li

Biotechnology Journal

DOI

2020

Cancer Liquid Biopsy Using Integrated Microfluidic Exosome Analysis Platforms

Guiying Li, Weiwei Tang, Fang Yang

Biotechnology Journal

DOI

2019

Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis

Liangzhong Zhao, Jialiang Zhao, Ruijuan Gao, Yuan Tian, Ying Zhang, Weiwei Tang, Yu Jiang, Chengjuan Li, Manning Wang, Fang Yang, Guiying Li

Biomedicine & Pharmacotherapy

DOI

2019

TRIM59: A membrane protein expressed on Bacillus Calmette-Guérin-activated macrophages that induces apoptosis of fibrosarcoma cells by direct contact

Yuan Tian, Zheng Jin, Pei Zhu, Shanshan Liu, Dongxu Zhang, Mengyan Tang, Yuanxin Wang, Dong Li, Dongmei Yan, Guiying Li, Xun Zhu

Experimental Cell Research

DOI

2019

Intrabody against prolyl hydroxylase 2 promotes angiogenesis by stabilizing hypoxia-inducible factor-1α

Liangzhong Zhao, Ziyu Liu, Fang Yang, Ying Zhang, Ying Xue, Haipeng Miao, Xiangzhi Liao, Hongli Huang, Guiying Li

Scientific Reports

DOI

2018

Extraction of Cell-Free Whole Blood Plasma Using a Dielectrophoresis-Based Microfluidic Device

Fang Yang, Ying Zhang, Cui Xi, Yutong Fan, Ying Xue, Haipeng Miao, Guiying Li

Biotechnology Journal

DOI

2018

Subunits of human condensins are potential therapeutic targets for cancers

Hongzhen Wang, Sihan Yang, Guiying Li, Xudong Cao

Cell Division

DOI

2017

Prokaryotic expression, purification and characterization of human cyclooxygenase-2

Xiangzhi Liao, Wenhan Wang, Chuanxi Fan, Ning Yang, Jialiang Zhao, Ying Zhang, Ruijuan Gao, Guannan Shen, Simin Xia, Guiying Li

International Journal of Molecular Medicine

DOI

2017

New cofactors and inhibitors for a DNA-cleaving DNAzyme: superoxide anion and hydrogen peroxide mediated an oxidative cleavage process

Yanhong Sun, Rulong Ma, Shijin Wang, Guiying Li, Yongjie Sheng, Hongyue Rui, Jin Chi Zhang, Jiacui Xu, Dazhi Jiang

Scientific Reports

DOI

2017

The Triple Roles of Glutathione for a DNA-Cleaving DNAzyme and Development of a Fluorescent Glutathione/Cu2+-Dependent DNAzyme Sensor for Detection of Cu2+ in Drinking Water

Shijin Wang, Chengcheng Liu, Guiying Li, Yongjie Sheng, Yanhong Sun, Hongyue Rui, Jin Chi Zhang, Jiacui Xu, Dazhi Jiang

ACS Sensors

DOI

2017

Exosome separation using microfluidic systems: size‐based, immunoaffinity‐based and dynamic methodologies

Fang Yang, Xiangzhi Liao, Yuan Yu Tian, Guiying Li

Biotechnology Journal

DOI

2015

Interaction of AIM with insulin-like growth factor-binding protein-4

Qiang You, YAN WU, NANNAN YAO, Guannan Shen, Ying Zhang, Liang‐Guo Xu, Guiying Li, Cynthia Ju

International Journal of Molecular Medicine

DOI

2013

Expression and purification of a human anti-cyclin D1 single-chain variable fragment antibody AD5 and its characterization

Yan Wu, Desheng Zou, Yuhua Cao, Nannan Yao, Junye Wang, Wenhan Wang, Hongyu Jiang, Guiying Li

International Journal of Molecular Medicine

DOI

2013

Role of hepatic resident and infiltrating macrophages in liver repair after acute injury

Qiang You, Michael R. Holt, Hao Yin, Guiying Li, Cheng‐Jun Hu, Cynthia Ju

Biochemical Pharmacology

DOI

2013

Characterization of the Interaction between Eupatorin and Bovine Serum Albumin by Spectroscopic and Molecular Modeling Methods

Hongliang Xu, Nannan Yao, Haoran Xu, Tianshi Wang, Guiying Li, Zhengqiang Li

International Journal of Molecular Sciences

DOI

2013

Spectroscopic Studies on the Interaction Between Aucubin and Bovine Serum Albumin Without or With Copper II or Iron III

Hongliang Xu, Nannan Yao, Guiying Li, Zhengqiang Li

Spectroscopy Letters

DOI

2011

Cytosolic phospholipase A2α protects against Fas- but not LPS-induced liver injury

Guiying Li, Weina Chen, Chang Lung Han, Tong Wu

Journal of Hepatology

DOI

2010

Cytosolic phospholipase A2α and peroxisome proliferator‐activated receptor γ signaling pathway counteracts transforming growth factor β–mediated inhibition of primary and transformed hepatocyte growth†

Chang Lung Han, William C. Bowen, Guiying Li, Anthony Jake Demetris, George K. Michalopoulos, Tong Wu

Hepatology

DOI

2010

Regulation of STAT3 pathway by cPLA2α and PPARδ

Chang Lung Han, Guiying Li, Shuo Huang, Tong Wu

The FASEB Journal

DOI

2010

Prevention of Fas‐Induced Liver Injury by cytosolic Phospholipase A2α

Guiying Li, Chang Han, Tong Wu

The FASEB Journal

DOI

2008

抗Cyclin D1胞内抗体AD5N对宫颈癌HeLa细胞的影响

周立宏，朱迅，曹玉华，陈勇，田宇，王磊，李桂英

《中国肿瘤临床》

2008

内质网滞留型抗CyclinD1胞内抗体在HeLa细胞中的表达分析

周立宏，朱迅，田宇，陈勇，曹玉华，冯晶，李桂英

《中国实验诊断学》

2008

抗Cyclin D1胞内抗体AD5N基因真核表达载体的构建及其对乳腺癌细胞增殖的抑制作用

周立宏，朱迅，曹玉华，王磊，陈勇，杜柏榕，李桂英

《中国免疫学杂志》

2008

Transgenic Expression of Cyclooxygenase-2 in Hepatocytes Accelerates Endotoxin-Induced Acute Liver Failure

Chang Lung Han, Guiying Li, Kyu Lim, Marie C. DeFrances, Chandrashekhar R. Gandhi, Tong Wu

The Journal of Immunology

DOI

2008

Prokaryotic Expression,Purification and Renaturation of Recombinant Human CDK4

Guiying Li

Journal of Jilin University(Science Edition)

2008

Effects of Anti-cyclin D1 Intrabody AD5N on HeLa Cervical Cancer Cells

Guiying Li

Clinical Oncology and Cancer Research

精选作品

期刊论文

Corrigendum to "An intrabody targeting PHD2 protects mice against acetaminophen-induced liver injury by attenuating ferroptosis" [Free Radic. Biol. Med. 243 (2026) 260-275].

Immunofluorescent analysis of exosomes using a microchip filled with transparent antibody-conjugated beads for breast cancer liquid biopsy.

The role of rare ginsenosides in the prevention and treatment of liver diseases.

Small Extracellular Vesicles Detection by Dielectrophoresis-Based Microfluidic Chip Filled with Transparent Antibody-Conjugated Microbeads for Breast Cancer Diagnosis.

An Intrabody Targeting PHD2 Protects Mice against Acetaminophen-Induced Liver Injury by Attenuating Ferroptosis.

Small extracellular vesicles detection using dielectrophoresis-based microfluidic chip for diagnosis of breast cancer.

The Regulation of Exosome Generation and Function in Physiological and Pathological Processes

The role of TRIM family in metabolic associated fatty liver disease

A specific anti-cyclin D1 intrabody represses breast cancer cell proliferation by interrupting the cyclin D1–CDK4 interaction

Electrolysis of Bacteria Based on Microfluidic Technology

Immunofluorescence analysis of breast cancer biomarkers using antibody-conjugated microbeads embedded in a microfluidic-based liquid biopsy chip

Biochemical Reaction Acceleration by Electrokinetic Mixing in a Microfluidic Chip

Clot structure-based physical-matching design of platelet cloaking nano-delivery system facilitates specific arteriovenous thrombolysis

The Role of Exosomes in Inflammatory Diseases and Tumor-Related Inflammation

Expression, purification and characterisation of a human anti-CDK4 single-chain variable fragment antibody

Explore a novel function of human condensins in cellular senescence

Separation of Macrophages Using a Dielectrophoresis-Based Microfluidic Device

A Cyclin D1‐Specific Single‐Chain Variable Fragment Antibody that Inhibits HepG2 Cell Growth and Proliferation

Cancer Liquid Biopsy Using Integrated Microfluidic Exosome Analysis Platforms

Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis

TRIM59: A membrane protein expressed on Bacillus Calmette-Guérin-activated macrophages that induces apoptosis of fibrosarcoma cells by direct contact

Intrabody against prolyl hydroxylase 2 promotes angiogenesis by stabilizing hypoxia-inducible factor-1α

Extraction of Cell-Free Whole Blood Plasma Using a Dielectrophoresis-Based Microfluidic Device

Subunits of human condensins are potential therapeutic targets for cancers

Prokaryotic expression, purification and characterization of human cyclooxygenase-2

New cofactors and inhibitors for a DNA-cleaving DNAzyme: superoxide anion and hydrogen peroxide mediated an oxidative cleavage process

The Triple Roles of Glutathione for a DNA-Cleaving DNAzyme and Development of a Fluorescent Glutathione/Cu2+-Dependent DNAzyme Sensor for Detection of Cu2+ in Drinking Water

Exosome separation using microfluidic systems: size‐based, immunoaffinity‐based and dynamic methodologies

Interaction of AIM with insulin-like growth factor-binding protein-4

Expression and purification of a human anti-cyclin D1 single-chain variable fragment antibody AD5 and its characterization

Role of hepatic resident and infiltrating macrophages in liver repair after acute injury

Characterization of the Interaction between Eupatorin and Bovine Serum Albumin by Spectroscopic and Molecular Modeling Methods

Spectroscopic Studies on the Interaction Between Aucubin and Bovine Serum Albumin Without or With Copper II or Iron III

Cytosolic phospholipase A2α protects against Fas- but not LPS-induced liver injury

Cytosolic phospholipase A2α and peroxisome proliferator‐activated receptor γ signaling pathway counteracts transforming growth factor β–mediated inhibition of primary and transformed hepatocyte growth†

Regulation of STAT3 pathway by cPLA2α and PPARδ

Prevention of Fas‐Induced Liver Injury by cytosolic Phospholipase A2α

抗Cyclin D1胞内抗体AD5N对宫颈癌HeLa细胞的影响

内质网滞留型抗CyclinD1胞内抗体在HeLa细胞中的表达分析

抗Cyclin D1胞内抗体AD5N基因真核表达载体的构建及其对乳腺癌细胞增殖的抑制作用

Transgenic Expression of Cyclooxygenase-2 in Hepatocytes Accelerates Endotoxin-Induced Acute Liver Failure

Prokaryotic Expression,Purification and Renaturation of Recombinant Human CDK4

Effects of Anti-cyclin D1 Intrabody AD5N on HeLa Cervical Cancer Cells

会议论文

靶向CyclinD1-CDK4激酶复合物的肝癌治疗研究

胞内抗体肝癌靶向治疗研究

抗CDK4胞内抗体抑制肝癌细胞生长和增殖

靶向CDK4胞内抗体的制备及其抑瘤效应分析

靶向Cyclin D1/CDK4激酶复合物胞内抗体的生物学作用

抗Cyclin D1胞内抗体抑制乳腺癌细胞生长的分子机制

靶向Cyclin D1胞内抗体抑制乳腺癌细胞的生长和转移

内质网滞留型抗Cyclin D1胞内抗体的抑瘤效应分析

抗CDK4人源单链抗体的作用机制研究

肿瘤特异性抗CDK4胞内抗体的体内外抑瘤效应分析

抗Cyclin D1胞内抗体与p16联合抑制乳腺癌细胞的增殖

研究方向