段广才｜郑州大学｜学者主页

2026

重症发热伴血小板减少综合征预测模型的构建

鲁赛威，胡艳，杨岩岩，陈俊东，胡泉满，赵菲，欧阳凡，苏文垚，张丽，陈帅印，段广才

《郑州大学学报(医学版)》

2026

李爽，梁若楠，朱培育，纪望全，晋乐飞，段广才

《病毒学报》

2024

Yehao Jin, Yankai Li, J W Li, Zhiling Yan, S Y Chen, Xuyan Lou, K Fan, F Wu, Y Y Cao, F Y Hu, L. Chen, Y Q Xie, C Cheng, H Y Yang, Guangcai Duan

PubMed

DOI

2022

肠道病毒感染致神经损伤小鼠脑组织NOD样受体蛋白3的表达

张梦娣，梁若楠，纪望全，张雪，陈晨，闫玉洁，张楚雯，朱培育，李栋，陈帅印，杨海燕，段广才，晋乐飞

《郑州大学学报(医学版)》

2022

中国柯萨奇病毒A组6型分离株全基因序列特征分析

董小聪，纪望全，陈帅印，杨海燕，段广才，晋乐飞

《中华疾病控制杂志》

2022

中国柯萨奇病毒A组2型的遗传进化分析

梁若楠，孙甜甜，纪望全，陈帅印，杨海燕，段广才，晋乐飞

《中华疾病控制杂志》

2022

胡泉满，程诚，李杨，高艳蕾，陈帅印，段广才

《现代预防医学》

2021

SARS-CoV-2 Nsp8基因及蛋白分子特征探讨

张凌寒，晋乐飞，陈帅印，岳利敏，段广才

《中华疾病控制杂志》

DOI

2021

CRISPR/Cas12-Based Ultra-Sensitive and Specific Point-of-Care Detection of HBV

Ronghua Ding, Jin-Zhao Long, Ming-Zhu Yuan, Xue Zheng, Yue Shen, Yue-Fei Jin, Hai-Yan Yang, Hao Li, Shuai-Yin Chen, Guang-Cai Duan

International Journal of Molecular Sciences

DOI

2021

Recombination Lactococcus lactis expressing Helicobacter pylori neutrophil-activating protein A attenuates food allergy symptoms in mice.

Ke Zhang, Wajid Ameen Mirza, Peng Ni, Mingyang Yu, Chen Wang, Bin Wang, Shuailei Chang, Li-Min Yue, Rong-Guang Zhang, Guang-Cai Duan

FEMS Microbiology Letters

DOI

2021

Neonatal Murine Model of Coxsackievirus A2 Infection for the Evaluation of Antiviral Therapeutics and Vaccination

W. Ji, Lu-Wei Qin, L. Tao, P. Zhu, R. Liang, Guang-Yuan Zhou, Shuai-Yin Chen, Weiguo Zhang, Hai-Yan Yang, Guang-Cai Duan, Yue-Fei Jin

Frontiers in Microbiology

DOI

2021

张荣光，陈帅印，郗园林，段广才

《中国卫生检验杂志》

2019

中国2008-2016年手足口病月发病率时间序列分析及预测模型

熊昱阳，任静朝，段广才

《中华疾病控制杂志》

DOI

2019

医院污水中大肠埃希菌的耐药谱及Ⅰ类整合子分析

滕妍利，欧柳阳，段广才，李栋，刘俏丽，李梦臣，陈帅印，郗园林

《中国病原生物学杂志》

DOI

2019

儿童手足口病合并呼吸道感染住院时间与血常规的关系

任静朝，段广才，周广远，秦露伟，杨道坤，申宝深，张光文

《广东医学》

2018

郑州市冬季雾霾空气中细菌的多样性及耐药性检测

李梦臣，刘俏丽，段广才，晋乐飞，李影，孙甜甜，吴慧颖，党德建，刘慧莹，徐亚珂，陈帅印，郗园林

《郑州大学学报(医学版)》

2018

Lu Chen, Jing-Chao Ren, Guang-Cai Duan, Guang-Yuan Zhou

DOI

2017

Emergence and mechanism of carbapenem-resistant Escherichia coli in Henan, China, 2014.

W. Liang, Hui-Ying Liu, Guang-Cai Duan, Yong-Xin Zhao, Shuai-Yin Chen, Hai-Yan Yang, Yuan-Lin Xi

Journal of Infection and Public Health

DOI

2017

Involvement of inducible nitric oxide synthase and mitochondrial dysfunction in the pathogenesis of enterovirus 71 infection

De-Jian Dang, Chao Zhang, Rong-Guang Zhang, Wei-Dong Wu, Shuai-Yin Chen, Jing-Chao Ren, P. Zhang, Guang-Yuan Zhou, De-Min Feng, Tian-Tian Sun, Y. Li, Qiao-Li Liu, Mengchen Li, Yuan-Lin Xi, Yue-Fei Jin, Guang-Cai Duan

OncoTarget

DOI

2017

An engineered food-grade Lactococcus lactis strain for production and delivery of heat-labile enterotoxin B subunit to mucosal sites

Nan Sun, Rong-Guang Zhang, Guang-Cai Duan, Xiao-Yan Peng, Chen Wang, Q. Fan, Shuai-Yin Chen, Yuan-Lin Xi

2015

马晓梅，隋美丽，段广才，陈帅印，张荣光，郗园林，范清堂

《中国公共卫生》

2014

Detection and Analysis of CRISPRs of Shigella

Xiang-Jiao Guo, Ying-Fang Wang, Guang-Cai Duan, Z. Xue, Lin-Lin Wang, Peng-Fei Wang, S. Qiu, Yuan-Lin Xi, Hai-Yan Yang

Current Microbiology

DOI

宋春花，王颖芳，郗园林，段广才

《中国公共卫生》

2013

幽门螺杆菌HspA乳酸菌疫苗构建及免疫反应性鉴定

张小娟，王新彩，段广才，张荣光

《中国公共卫生》

2013

Prevalence and characterisation of plasmid-mediated quinolone resistance and mutations in the gyrase and topoisomerase IV genes among Shigella isolates from Henan, China, between 2001 and 2008.

Hai-Yan Yang, Guang-Cai Duan, Jing-Yuan Zhu, Wei-Dong Zhang, Yuan-Lin Xi, Q. Fan

International Journal of Antimicrobial Agents

DOI

2013

Transposition of ISEcp1 modulates blaCTX-M-55-mediated Shigella flexneri resistance to cefalothin.

Ying-Fang Wang, Chunhua Song, Guang-Cai Duan, Jing-Yuan Zhu, Hai-Yan Yang, Yuan-Lin Xi, Q. Fan

International Journal of Antimicrobial Agents

DOI

2013

The rOmp22–HpaA Fusion Protein Confers Protective Immunity Against Helicobacter pylori in Mice

Xueyong Huang, Bian-Li Xu, Guang-Cai Duan, Chunhua Song

Current Microbiology

DOI

2012

2010年郑州肠道病毒71型VP1基因和5’非编码区核酸序列分析

马元鹏，段广才，范张洁，张卫东，郗园林

《现代预防医学》

2012

志贺菌敏感株诱导耐药与marOR基因突变关系

王颖芳，宋春花，段广才，郗园林

《中国公共卫生》

2012

Chengzong Yang, Shuai-Yin Chen, Guang-Cai Duan

Current Microbiology

DOI

2011

Optimizing expression of Helicobacter pylori ureB gene in Lactococcus lactis NZ3900

Guang-Cai Duan

2011

The gene characterizationof VP1 and 2A of Enterovirus type 71

Zhang-Jie Fan, Guang-Cai Duan, Wei-Dong Zhang, Yuan-Lin Xi

DOI

2011

Food-Grade Expression of Helicobacter pylori UreB Subunit in Lactococcus lactis and its Immunoreactivity

Shuai-Yin Chen, Rong-Guang Zhang, Guang-Cai Duan, Jianxiang Shi

Expression of HpaA protein from Helicobacter pylori in E. coli and its immunoprotection.

Xueyong Huang, Bian-Li Xu, Guang-Cai Duan, Q. Fan, Yuan-Lin Xi

2010

Mutation of iceA in Helicobacter pylori compromised IL‐8 induction from human gastric epithelial cells

Yi-Jun Ma, Guang-Cai Duan, Rong-Guang Zhang, Qing-Tang Fan, Wei-Dong Zhang

Journal of Basic Microbiology

DOI

2010

The relationship between marOR mutations and the antibiotic resistance in Shigella spp

Jing-Chao Ren, Guang-Cai Duan, Hai-Yan Yang, L. Rui-li, Wei-Dong Zhang, Yuan-Lin Xi

DOI

2010

[Serotypes characterization and antimicrobial resistance on Shigella isolated from the Sui county during 2001-2008].

Hai-Yan Yang, Guang-Cai Duan, Wei-Dong Zhang, Jing-Yuan Zhu, Yuan-Lin Xi, Yu Ma

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

DOI

2010

Xiao-Juan Zhang, Guang-Cai Duan, Rong-Guang Zhang, Q. Fan

Current Microbiology

DOI

2009

Mutation of cytotoxin-associated gene A affects expressions of antioxidant proteins of Helicobacter pylori.

Zhi-Gang Huang, Guang-Cai Duan, Q. Fan, Wei-Dong Zhang, Chunhua Song, Xue-Yong Huang, Rong Zhang

World Journal of Gastroenterology

DOI

2008

志贺菌临床分离株耐多药与调控基因突变关系

吕锐利，段广才，宋春花，郗园林

《中国公共卫生》

2008

志贺菌敏感株与基因转移耐多药株蛋白组学分析

宋春花，黄学勇，郗园林，张梅喜，段广才

《中国公共卫生》

2008

志贺菌属细菌主动外排作用的诱导检测

符幸涛，段广才，郗园林

《现代预防医学》

2008

The AcrAB-TolC Pump Is Involved in Multidrug Resistance in Clinical Shigella flexneri Isolates

Hai-Yan Yang, Guang-Cai Duan, Jing-Yuan Zhu, Rui-Li Lv, Yuan-Lin Xi, Wei-Dong Zhang, Q. Fan, Mei-Xi Zhang

赵玉霞，齐建华，章涵，段广才，郗园林

《细胞与分子免疫学杂志》

2007

Establishment of two-dimensional proteome map of Shigella flexneri

Guang-Cai Duan

2007

[Construction, expression and purification of UreB-Omp11 fusion protein of Helicobacter pylori and its immunocompetence].

Yu-Xia Zhao, J. Qi, Han Zhang, Guang-Cai Duan, Yuan-Lin Xi

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology

2007

Guang-Cai Duan

2006

Construction and identification of Chinese mutant Helicobacter pylori strain with absent expression of cagA gene

Zhi-Gang Huang, Guang-Cai Duan, Q. Fan, Xue-Yong Huang

DOI

2006

Spread of HIV in one village in central China with a high prevalence rate of blood-borne AIDS.

Wei-Dong Zhang, Dongsheng Hu, Yuanlin Xi, Mei-Xi Zhang, Guang-Cai Duan

International Journal of Infectious Diseases

DOI

2006

Coinfection of HIV, HBV,and HCV in a village with high prevalence rate of blood-related AIDS

Guang-Cai Duan

2006

血源性艾滋病高发村村民HIV/HBV/HCV混合感染状况调查

张卫东，郗园林，张梅喜，段广才

《郑州大学学报(医学版)》

2005

大肠杆菌不耐热肠毒素基因克隆和无毒突变体mLT63的构建及序列分析

申晓靖，段广才，郗园林，代丽萍，康巧珍

《河南医学研究》

2005

幽门螺杆菌flaB基因克隆及序列分析

夏晓燕，段广才，代丽萍，范清堂

《现代预防医学》

2005

编写一本适合临床专业学生使用的《预防医学》

傅华，段广才

《上海预防医学》

DOI

2005

主动外排系统acrAB在志贺菌中分布和表达

杨海燕，段广才，郗园林

《中国公共卫生》

2005

Purification and characterization of recombinant HspA-UreB fusion protein of Helicobacter pylori from inclusion body

Guang-Cai Duan

2005

幽门螺杆菌融合蛋白HspA-UreB在pMAL-C2x中的表达与免疫学活性研究

代丽萍，段广才，范清堂，张荣光

《河南医学研究》

2005

Fusion expression of Helicobacter pylori neutrophil-activating protein in E.coli.

Qiaozhen Kang, Guang-Cai Duan, Q. Fan, Yuan-Lin Xi

Guang-Cai Duan

2004

Cloning and sequence analysis of neutrophil-activating protein gene napA of H.pylori

Guang-Cai Duan

2004

Rong-Guang Zhang, Guang-Cai Duan, Yuan-Lin Xi

2003

Cloning and expression of the Ipp20 gene of Helicobacter pylori

Guang-Cai Duan

2002

幽门螺杆菌的分子分型及其分子流行病学研究

代敏，段广才，范清堂，郗园林，李倩，施侣元

《中国公共卫生》

2002

RAPD法对50株幽门螺杆菌的分子流行病学

代敏，段广才，郗园林，范清堂，李倩，施侣元

《中华疾病控制杂志》

1995

霍乱弧菌O139与O1及非O1菌关系的研究

段广才，高守一，祁国明，刘延清

《中华微生物学和免疫学杂志》

精选作品

期刊论文

重症发热伴血小板减少综合征预测模型的构建

尼帕病毒流行病学研究进展

Clinical outcomes and safety of tocilizumab in severe fever with thrombocytopenia syndrome: a retrospective multicenter cohort study

Nipah virus: An exceptionally virulent emerging zoonotic pathogen

The C5a-C5aR1 axis facilitates blood-brain barrier disruption induced by EV-A71 infection through neutrophil activation

Coxsackievirus A6 infection exacerbates kidney injury in mice through the p38-MAPK pathway

High-Risk CCL14 lineage drives severe Mycoplasma pneumoniae pneumonia in children: a study in central China

Tracking Global Transmission Dynamics of the Plasmid-Mediated mcr Gene: A Genomic Epidemiological Analysis

Long Non-Coding RNA NEAT1 Inhibits Enterovirus 71 Replication by Enhancing IFN-β Transcription Through DDX60 Signaling: Pathological Insights and Clinical Implications

Epidemiological characteristics of infectious mononucleosis among hospitalized children in Henan Province, China: a retrospective study

Advancing precision antiviral therapy: The value, challenges, and prospects of a novel antiviral crRNA screening platform

Current status of severe fever with thrombocytopenia syndrome in China (Review)

Efficacy, Immunogenicity, and Safety of Pertussis Vaccine During Pregnancy: A Meta-Analysis

Epidemiological Analysis of Hand, Foot, and Mouth Disease Caused by CVA10

Childhood hand, foot and mouth disease sequelae cohort study in Henan, China: cohort profile

线粒体凋亡参与EV-71感染致人微血管内皮细胞损伤的机制

基于CRISPR序列的致泻性大肠埃希菌跨种传播风险机器学习模型构建

Unveiling the drivers of vancomycin-resistant enterococcus in China: A comprehensive ecological study

The longitudinal trend and driving factors of antimicrobial resistance among Streptococcus pneumoniae worldwide

Metabolomic analysis reveals an important role of sphingosine 1-phosphate in the development of HFMD due to EV-A71 infection

NLRP3 inflammasome activation contributes to acute liver injury caused by CVA6 infection in mice

Epidemiological characterization of hand, foot, and mouth disease among hospitalized children from 2014 to 2023 in a hospital in Henan Province: Longitudinal surveillance study

Advances in antibacterial activity of zinc oxide nanoparticles against Staphylococcus aureus (Review)

Recent advances in the use of resveratrol against Staphylococcus aureus infections (Review)

The longitudinal trend and influential factors exploring of global antimicrobial resistance in Klebsiella pneumoniae

The key mechanisms of multi-system responses triggered by central nervous system damage in hand, foot, and mouth disease severity

Review on Long Non-Coding RNAs as Biomarkers and Potentially Therapeutic Targets for Bacterial Infections

N6-methyladenosine modification of hypoxia-inducible factor-1α regulates Helicobacter pylori-associated gastric cancer via the PI3K/AKT pathway

The application of CRISPR-Cas system in Staphylococcus aureus infection

Global epidemiology and genetic diversity of mcr-positive Klebsiella pneumoniae: A systematic review and genomic analysis

Global distribution and genetic characterization of blaOXA-positive plasmids in Escherichia coli

[Epidemiological characteristic of viral encephalitis in children and adolescents in Henan Province, 2012-2023].

The Application of Rat Models in Staphylococcus aureus Infections

In vitro study of HPV18-positive cervical cancer HeLa cells based on CRISPR/Cas13a system

Epidemiology and etiology of hand, foot, and mouth disease in Zhengzhou, China, from 2009 to 2021

A Recombinant CVA6 Infection Aggravates Left Ventricular Dysfunction and Myocardial Injury in a Child With Cardiomyopathy

Emerging concerns of blood-brain barrier dysfunction caused by neurotropic enteroviral infections

Visualizing in-field detection of HCV using a one-pot RT-RAA-CRISPR/Cas12a platform

A non-autonomous time-delayed SIR model for COVID-19 epidemics prediction in China during the transmission of Omicron variant

科研反哺教学在卫生微生物实验教学中的探索与实践

Progress and bioapplication of CRISPR-based one-step, quantitative and multiplexed infectious disease diagnostics.

Arising Concerns of Atypical Manifestations in Patients with Hand, Foot, and Mouth Disease

Local immune dysregulation and subsequent inflammatory response contribute to pulmonary edema caused by Enterovirus infection in mice

Mechanism of RNA m6A methylation modification regulating NLRP3 inflammasome activation for hand, foot, and mouth disease progression

Effectiveness of mRNA vaccine against Omicron-related infections in the real world: A systematic review and meta-analysis.

A mouse model and pathogenesis study for CVA19 first isolated from hand, foot, and mouth disease

Current status of hand-foot-and-mouth disease

Genomic Insights into CRISPR-Harboring Plasmids in the Klebsiella Genus: Distribution, Backbone Structures, Antibiotic Resistance, and Virulence Determinant Profiles

Transmission of livestock-associated methicillin-resistant Staphylococcus aureus between animals, environment, and humans in the farm

Involvement of RNA chaperone Hfq in the regulation of antibiotic resistance and virulence in Shigella sonnei.

Analysis of the features of 105 confirmed CRISPR loci in 487 Klebsiella variicola.

Hand, Foot, and Mouth Disease Challenges and Its Antiviral Therapeutics

Active inoculation with an inactivated Coxsackievirus A2 vaccine induces neutralizing antibodies and protects mice against lethal infection.

A review on circular RNAs and bacterial infections.

Latest Advances in the Application of Humanized Mice Model for Staphylococcus aureus.

TBK1 and IRF3 are potential therapeutic targets in Enterovirus A71-associated diseases

Impact of non-pharmaceutical interventions during COVID-19 pandemic on measles and mumps in Mainland China

Genome mining reveals the prevalence and extensive diversity of toxin–antitoxin systems in Staphylococcus aureus

Epidemiological characteristics and dynamic transmissions of COVID-19 pandemics in Chinese mainland: A trajectory clustering perspective analysis.

Characterization and diversity of CRISPR/Cas systems in Klebsiella oxytoca

The association of sickle cell disorder with adverse outcomes in COVID‐19 patients: A meta‐analysis

Abundant Neutrophils-initiated Acute Myocardial Injury Following Coxsackievirus A6 Infection.

A meta-analysis of immunogenicity and safety of two versus single-doses of influenza A (H1N1) vaccine in person living with HIV

[Epidemiological investigation on the local epidemic situation in Zhengzhou High-Tech Zone caused by SARS-CoV-2 Delta variant].

肠道病毒感染致神经损伤小鼠脑组织NOD样受体蛋白3的表达

中国柯萨奇病毒A组6型分离株全基因序列特征分析

中国柯萨奇病毒A组2型的遗传进化分析

新型冠状病毒肺炎确诊患者首发临床症状分析

The CXCL10/CXCR3 Axis Promotes Disease Pathogenesis in Mice upon CVA2 Infection

NAFLD was independently associated with severe COVID-19 among younger patients rather than older patients: A meta-analysis

Differential Expression of α-Enolase in Clinical Gastric Tissues and Cultured Normal/Cancer Cells in Response to Helicobacter pylori Infection and cagA Transfection

Risk of adverse outcomes in inflammatory bowel disease patients infected with SARS-CoV-2: a systematic review and meta-analysis

The CRISPR-Cas system as a tool for diagnosing and treating infectious diseases

The crafty opponent: the defense systems of Staphylococcus aureus and response measures

An Update on Detection Technologies for SARS-CoV-2 Variants of Concern

Laboratory Indicators for Identifying Hand, Foot, and Mouth Disease Severity: A Systematic Review and Meta-Analysis

Editorial: The CRISPR/Cas System in Pathogen Resistance, Virulence, Diagnosis and Typing

Application of CRISPR/Cas Systems in the Nucleic Acid Detection of Infectious Diseases