百晓学者学者目录

王洋

副研究员、教授，复旦大学

精选作品

期刊论文

2026

人脐带间充质干细胞来源小胞外囊泡用于治疗放创复合型骨损伤的疗效研究

魏正阳，李雪，张昭玮，郑远静，王洋，刘元林，张毅

《军事医学》

2024

白细胞介素32对人脐带来源间充质干细胞向脂肪细胞分化的调控作用

张夏茹，赵薪丰，郑远静，刘元林，李雪，王洋，王丽峰，张毅

《中国药理学与毒理学杂志》

2023

壳多糖酶3样蛋白1对人脐带来源间充质干细胞成脂和成骨分化的调控作用

李曼，刘伟江，袁福临，白海涛，李雪，王洋，刘元林，焦宏，张毅

《中国药理学与毒理学杂志》

2023

CD200调控人脐带来源间充质干细胞增殖的实验研究

疏梦，张夏茹，刘元林，李雪，王洋，张毅

《军事医学》

2023

1型糖尿病脂肪来源间充质干细胞成骨分化的实验研究

许婷婷，刘伟江，吴楚姗，刘元林，王洋，郑荣秀，张毅

《军事医学》

2023

Nystose attenuates bone loss and promotes BMSCs differentiation to osteoblasts through BMP and Wnt/β-catenin pathway in ovariectomized mice

Qi Zhang, Sijing Hu, Jianjun Wu, Peng Sun, Quanlong Zhang, Yang Wang, Qiming Zhao, Ting Han, Luping Qin, Qiaoyan Zhang

Food Science and Human Wellness

2023

Activating translation by phase separation: a novel mechanism for driving spermiogenesis

Wenjing Zhang, Yang Wang

Science China Life Sciences

2022

POSTN基因调控人脐带间充质干细胞向成骨细胞分化的实验研究

于丰实，刘伟江，白海涛，袁福临，刘元林，李雪，王洋，张毅

《军事医学》

2022

高表达miR-25-3p对小鼠骨实质来源间充质干细胞成脂分化的抑制作用

袁福临，刘伟江，白海涛，李雪，王洋，刘元林，张毅

《中国药理学与毒理学杂志》

2021

幼龄1型糖尿病模型小鼠脂肪来源干细胞的鉴定及其成脂分化能力

张金霞，刘伟江，苏菲娅，张晗，于丰实，白海涛，袁福临，刘元林，李雪，王洋，郑荣秀，张毅

《中国药理学与毒理学杂志》

2021

Small extracellular vesicles secreted by urine-derived stem cells enhanced wound healing in aged mice by ameliorating cellular senescence

Yongjin Sun, Juntao Zhang, Bi Chen, Yunlong Yang, Haiyan Li, Xin Niu, Qing Li, Weidong Wu, Zongping Xie, Yunfeng Chen, Fuyue Wu, Yang Wang

Journal of Materials Science & Technology

2020

Wip1/PP2A通路调控小鼠间充质干细胞成脂肪细胞分化的实验研究

樊月，刘伟江，李雪，查兰兰，白海涛，刘元林，周斌，李培，于丰实，王洋，张毅

《军事医学》

2020

间充质干细胞对小鼠损伤性子宫内膜的修复作用

王洋

《河北医科大学》

2020

The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells

Deobrat Dixit, B. Prager, R. Gimple, Hui Xian Poh, Yang Wang, Qiulian Wu, Zhixin Qiu, Reilly L. Kidwell, Leo J. Y. Kim, Qi Xie, K. Vitting-Seerup, S. Bhargava, Zhen Dong, Li Jiang, Zhe Zhu, P. Hamerlik, S. Jaffrey, Jing Crystal Zhao, Xiu-Xing Wang, J. Rich

Cancer Discovery

DOI

2019

STAT1-CXCL9-10信号通路调控间充质干细胞免疫抑制作用的实验研究

周斌，刘伟江，查兰兰，李培，刘元林，樊月，于丰实，李雪，王洋，郑荣秀，张毅

《军事医学》

2019

Identification of a Xist silencing domain by Tiling CRISPR

Yang Wang, Yang Zhong, Ying-Yao Zhou, O. Tanaseichuk, Zhizhong Li, Jing Crystal Zhao

Scientific Reports

DOI

2018

间充质干细胞通过调控巨噬细胞极化减轻1型糖尿病模型小鼠炎症反应

周娜，刘伟江，李苹，孟祥宇，王洋，王鹏，樊月，刘元林，李雪，郑荣秀，张毅

《中国药理学与毒理学杂志》

2018

人脂肪间充质干细胞和滑膜间充质干细胞协同抑制炎性软骨细胞的退变

宋卓悦，王洋，连晓磊，丁康，李广恒

《中国组织工程研究》

2018

Publisher Correction: N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications

Yang Wang, Yue Li, Minghui Yue, Jun Wang, Sandeep Kumar, R. Wechsler-Reya, Zhaolei Zhang, Y. Ogawa, Manolis Kellis, G. Duester, Jing Crystal Zhao

Nature Neuroscience

DOI

2018

N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications

Yang Wang, Yue Li, Minghui Yue, Jun Wang, Sandeep Kumar, R. Wechsler-Reya, Zhaolei Zhang, Y. Ogawa, Manolis Kellis, G. Duester, Jing Crystal Zhao

Nature Neuroscience

DOI

2017

多能干细胞来源的肝细胞诱导分化及其应用研究进展

王洋，彭莹莹，段星祥，余娟，孙懿

《西北农林科技大学学报(自然科学版)》

2017

干细胞治疗终末期肝病的进展

段星祥，王洋，贺菁菁，彭莹莹，余娟，孙懿

《中南大学学报(医学版)》

2017

慢病毒介导CX43基因修饰小鼠骨髓间充质干细胞体系的建立及鉴定

王亚萍，司英健，王艳，邢国胜，王洋，封志纯

《中国小儿血液与肿瘤杂志》

2017

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells.

Huan-Huan Wei, Yuanlong Liu, Yang Wang, Qianyun Lu, Xue-Rong Yang, Jie-Fu Li, Ze-Feng Wang

Journal of Visualized Experiments

DOI

2017

Extensive translation of circular RNAs driven by N6-methyladenosine

Yun Yang, Xiaojuan Fan, Miaowei Mao, Xiaowei Song, Ping Wu, Yang Zhang, Yong-Feng Jin, Yi Yang, Ling-Ling Chen, Yang Wang, Catherine C. L. Wong, Xinshu Xiao, Ze-Feng Wang

Cell Research

DOI

2017

SMARCAD1 contributes to regulation of naïve pluripotency by interacting with histone citrullination

Shu Xiao, Jia Lu, Bharat Sridhar, Xiao-Yi Cao, Pengfei Yu, Tianyi Zhao, Chieh-Chun Chen, Darina McDee, Laura G. Sloofman, Yang Wang, Marcelo Rivas-Astroza, B. Telugu, D. Levasseur, Kang Zhang, Han Liang, Jing Crystal Zhao, Tetsuya S. Tanaka, G. Stormo, Sheng Zhong

Cell Reports

DOI

2016

An extensive program of periodic alternative splicing linked to cell cycle progression

Daniel Dominguez, Yi-Hsuan Tsai, Robert J. Weatheritt, Yang Wang, B. Blencowe, Ze-Feng Wang

eLife

DOI

2016

Author response: An extensive program of periodic alternative splicing linked to cell cycle progression

Daniel Dominguez, Yi-Hsuan Tsai, Robert J. Weatheritt, Yang Wang, B. Blencowe, Ze-Feng Wang

DOI

2016

Design of RNA-Binding Proteins: Manipulate Alternative Splicing in Human Cells with Artificial Splicing Factors.

Yang Wang, Ze-Feng Wang

Methods in molecular biology

DOI

2016

Update: Mechanisms underlying N6-methyladenosine modification of eukaryotic mRNA

Yang Wang, Jing Crystal Zhao

Trends in Genetics

DOI

2015

ISL1与PHF8相互作用促进小鼠胚胎干细胞向心肌细胞分化

李月娇，王洋，郭晨，贾竹青，王卫平，陈苹，马康涛，周春燕

《中国生物化学与分子生物学报》

2015

Efficient backsplicing produces translatable circular mRNAs

Yang Wang, Ze-Feng Wang

RNA: A publication of the RNA Society

DOI

2015

Genome-wide detection of high abundance N6-methyladenosine sites by microarray

Yue Li, Yang Wang, Zhaolei Zhang, A. V. Zamudio, Jing Crystal Zhao

RNA: A publication of the RNA Society

DOI

2014

Treatment of Type 1 Myotonic Dystrophy by Engineering Site-specific RNA Endonucleases that Target (CUG)n Repeats.

Wen-Jing Zhang, Yang Wang, S. Dong, Rajarshi Choudhury, Yong-Feng Jin, Ze-Feng Wang

Molecular Therapy

DOI

2014

N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells

Yang Wang, Yue Li, Julia I. Toth, M. Petroski, Zhaolei Zhang, Jing Crystal Zhao

Nature Cell Biology

DOI

2013

Recognition of self and altered self by T cells in autoimmunity and allergy

Lei Yin, Shaodong Dai, Gina Clayton, Wei Gao, Yang Wang, John Kappler, Philippa Marrack

Protein & Cell

2013

大鼠骨髓间充质干细胞培养方法的比较及细胞鉴定

杨陆蒙，李新喜，白超，王洋，田野，罗军

《新疆医科大学学报》

2013

Engineered proteins with PUF scaffold to manipulate RNA metabolism

Yang Wang, Ze-Feng Wang, Traci M. Tanaka Hall

The FEBS Journal

DOI

2013

Systematical identification of splicing regulatory cis-elements and cognate trans-factors

Yang Wang, Ze-Feng Wang

Methods

DOI

2013

Regulation of Mammalian Gene Dosage by Long Noncoding RNAs

Ko-Hsuan Hung, Yang Wang, Jing Crystal Zhao

Biomolecules

DOI

2012

骨髓间充质干细胞在骨髓衰竭小鼠体内的归巢及疗效观察

王洋

《南方医科大学》

2012

人脐血间充质干细胞移植对创伤性脑损伤大鼠血管新生及相关因子分泌的影响

陈乃耀，赵俊暕，石峻，王洋，孟爱国，赵辉

《临床血液学杂志》

2012

A Classification Method for RNA Splicing Regulatory Elements

Meng Ma, Yang Wang, Ying Ru, Ze-Feng Wang

DOI

2012

Intronic Splicing Enhancers, Cognate Splicing Factors and Context Dependent Regulation Rules

Yang Wang, Meng Ma, Xinshu Xiao, Ze-Feng Wang

Nature Structural &Molecular Biology

DOI

2012

A Complex Network of Factors with Overlapping Affinities Repress Splicing through Intronic Elements

Yang Wang, Xin-Shu Xiao, Jianming Zhang, Rajarshi Choudhury, Alex Robertson, Kai Li, Meng Ma, C. Burge, Ze-Feng Wang

Nature Structural &Molecular Biology

DOI

2012

Engineering RNA Endonucleases with Customized Sequence Specificities

Rajarshi Choudhury, Yi-Hsuan S. Tsai, Daniel Dominguez, Yang Wang, Ze-Feng Wang

Nature Communications

DOI

2011

人类胚胎干细胞系H9培养和分化中细胞异质性的发现

田靖，岳文，范秋声，陈娜，刘晓杰，王洋，赵志虎，裴雪涛，陈惠鹏

《生物技术通讯》

2011

肿瘤干细胞生长相关的信号转导通路

王洋，张楠，刘艳，刘晶，叶福秀，邹伟

《中国生物化学与分子生物学报》

2011

A specific and modular binding code for cytosine recognition in PUF domains

S. Dong, Yang Wang, C. Cassidy-Amstutz, G. Lu, C. Qiu, R. Bigler, M. Jezyk, C. Li, Traci M. Tanaka Hall, Ze-Feng Wang

DOI

2011

Specific and Modular Binding Code for Cytosine Recognition in Pumilio/FBF (PUF) RNA-binding Domains*♦

S. Dong, Yang Wang, C. Cassidy-Amstutz, G. Lu, R. Bigler, M. Jezyk, Chunhua Li, Traci M. Tanaka Hall, Ze-Feng Wang

Journal of Biological Chemistry

DOI

2009

体外增殖培养的骨髓间充质干细胞移植后在脑梗死大鼠脑内的存活

王洋，任力杰，韩漫夫，张朝东

《中国脑血管病杂志》

2009

Engineering artificial splicing factors with designed specificities

Ze-Feng Wang, Yang Wang, C. Cheong, Traci M. Tanaka Hall

DOI

2009

Engineering splicing factors with designed specificities

Yang Wang, C. Cheong, Traci M. Tanaka Hall, Ze-Feng Wang

Nature Methods

DOI

会议论文

2024

HIF-1α/HO-1轴正向调控低氧下牙周膜干细胞铁死亡的发生及其机制研究

常晓驰，王洋，侯建霞

《中华口腔医学会牙周病学专业委员会第16次牙周病学学术会议》

2019

LRP5对骨髓间充质干细胞成骨分化的影响

王洋，姜治伟，杨国利

《2019第九次全国口腔生物医学学术年会论文汇编》

DOI

研究方向

干细胞和细胞核无膜细胞器

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