袁建勇｜重庆医科大学｜学者主页

2026

I2–DMSO-Mediated In Situ Capture of Ketenimine Cations by Two Molecules of 3-Aminoindazole for the Synthesis of 1-(1 H -Indazol-3-yl)-2,4-Diphenyl-1 H -Pyrrolo[2′,3′:4,5]Pyrimido[1,2- b ]Indazole Derivatives

Xiaoqiong Deng, Mengyi Guo, Xinxin Jia, Qian Guo, Yifan Song, Luoteng Cheng, Kezhi Chen, Jianyong Yuan

The Journal of Organic Chemistry

DOI

2025

Iron-catalyzed synthesis of 4-arylpyrimido[1,2-b]indazoles using 3-aminobenzindazole, phenylacetylene, and N,N-dimethylformamide as one-carbon synthon

Yifan Song, Suqin Shang, Qian Guo, Xiaoqing Deng, Xinxin Jia, Mengyi Guo, Luoteng Cheng, Jianyong Yuan

Tetrahedron

DOI

2025

I2-DMSO-Mediated Three-Component Cyclization of 2-Aminobenzimidazole to Access 2,3-Substituted Benzo[4,5]imidazo[1,2-a]pyrimidine Derivatives

Mengyi Guo, Qian Guo, Wei Yuan, Shenkun Liao, Luoteng Cheng, Jianyong Yuan

Synthesis

DOI

2025

I 2 -DMSO-mediated [4 + 2] cyclization of methyl ketone with 2-aminobenzimidazole to construct 2,4-disubstituted benzo[4,5]imidazo[1,2- a ] pyrimidines

Qian Guo, Mengyi Guo, Luoteng Cheng, Yifan Song, Wanqian Ma, Yibo Song, Suzhen Li, Xiaoqiong Deng, Xinxin Jia, Jianyong Yuan

Organic & Biomolecular Chemistry

DOI

2024

A Metal-Free Strategy for the Synthesis of Symmetrical 2,3,5,6-Tetrasubstituted Pyridines Using Triethyl Orthoformate as a Carbon Source

Luoteng Cheng, Su-Qin Shang, Yan-Wu Li, Xiuyu Zhang, Suzhen Li, Wanqian Ma, Mengyi Guo, Yi-Bo Song, Qian Guo, Yi-Fan Song, Jianyong Yuan

Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry

DOI

2024

Theoretical insights into the radical scavenging performance of common anti-agers from both kinetic and thermodynamic perspectives

Jianyong Yuan, Jiong-Hao He, Yuchen Zhang

Computational and Theoretical Chemistry

DOI

2023

Synthesis of Substituted of Benzo[4,5]imidazo[1,2-a]pyrimidines through (3 + 2+1) Cyclization of 2-Aminobenzimidazole, Acetophenone, and N,N-Dimethylformamide as One-Carbon Synthon

Mengyi Guo, Xin Huang, Suzhen Li, Wanqian Ma, Aqin Liu, Xiuyu Zhang, Qiulin Kuang, Luoteng Cheng, Yibo Song, Xueyuan Hu, Jianyong Yuan

The Journal of Organic Chemistry

DOI

2023

A metal-free and additive-free facile method for the synthesis of 1H-Perimidines

Suzhen Li, Suqin Shang, Xiuyu Zhang, Mengyi Guo, Wanqian Ma, Aqin Liu, Qiulin Kuang, Luoteng Cheng, Jianyong Yuan

Tetrahedron Letters

DOI

2023

One-pot Synthesis of 2,3-disubstituted-4(3H)-quinazolinone from o-aminobenzoic Acid and DMF Derivatives using Imidazole Hydrochloride as a Promoter

Yin Wang, Xiuyu Zhang, Suzhen Li, Mengyi Guo, Wanqian Ma, Jianyong Yuan

Current Organic Synthesis

DOI

2023

A Metal-Free strategy for the synthesis of tetrasubstituted Pyridines: Dimethyl sulfoxide as carbon source

Xiu Yu Zhang, Kai Liu, Suzhen Li, Yanwu Li, Yue Wu, Xiang Li, Xinping Ran, Aqin Liu, Jianyong Yuan

Tetrahedron Letters

DOI

2023

A rapid construction of 1,3,2-benzodiazaborininones [R–B(aam)] from boronic acids and anthranilamides

Siwei Liao, Kai Liu, Huili Wu, Qiulin Kuang, Xueyuan Hu, Yihao Li, Hongxiao Lu, Jianyong Yuan

RSC Advances

DOI

2023

Iron-Catalyzed [2+1+2+1] Annulation of Amines and N , N -Dimethyl Enaminones using N , N -Dimethylaminoethanol as a One-Carbon Synthon for the Synthesis of 1,4-Dihydropyridines

Wanqian Ma, Qiulin Kuang, Suzhen Li, Mengyi Guo, Yi-Bo Song, Luoteng Cheng, Jianyong Yuan

Synthesis

DOI

2022

Pyridine hydrochloride-promoted C C bond cleavage approach: A metal-free and peroxide-free facile method for the synthesis of amide derivatives

Aqin Liu, Yanwu Li, Xiuyu Zhang, Qiulin Kuang, Suzhen Li, Siwei Liao, Xin Huang, Yin Wang, Ping Xu, Huili Wu, Mengyi Guo, Wanqian Ma, Yibo Song, Xueyuan Hu, Jianyong Yuan

Tetrahedron Letters

DOI

2022

Ionic melting salt imidazole hydrochloride mediated the decarboxylation of (hetero)aromatic carboxylic acids

Yin Wang, Ping Xu, Yanwu Li, Yue Wu, Siwei Liao, Xin Huang, Xiuyu Zhang, Jianyong Yuan

Tetrahedron Letters

DOI

2022

Imidazole Hydrochloride Promoted Synthesis of Nitriles from Aldehydes

Jianyong Yuan, Suqin Shang, Yin Wang, Xuetong Wang, Yanwu Li, Xiuyu Zhang, Lingli Li, Tingshu He

Current Organic Synthesis

DOI

2022

Imidazolium chloride as an additive for synthesis of perimidines using 1,8-diaminonaphthalene and DMF derivatives

Xiuyu Zhang, Siwei Liao, Aqin Liu, Xiao‐Ling Liu, Qiulin Kuang, Yin Wang, Ping Xu, Xin Huang, Huili Wu, Jianyong Yuan

Tetrahedron Letters

DOI

2022

A rapid construction of new boron heterocycles and evaluation of photophysical properties of iminoboronates

Qiulin Kuang, Xueyuan Hu, Yanwu Li, Suqin Shang, Xin Huang, Siwei Liao, Yibo Song, Wanqian Ma, Suzhen Li, Aqin Liu, Xiaoling Liu, Xiuyu Zhang, Jianyong Yuan

Organic & Biomolecular Chemistry

DOI

2021

Discovery Studio软件在药物化学教学中的应用

邓萍，蒋君好，余瑜，胡湘南，袁建勇，甘宗捷

《药学教育》

DOI

2021

Imidazole hydrochloride promoted synthesis of 3,5-disubstituted-1,2,4-oxadiazoles

Xuetong Wang, Yin Wang, Xiao‐Ling Liu, Tingshu He, Lingli Li, Huili Wu, Shangjun Zhou, Dan Li, Siwei Liao, Ping Xu, Xing Huang, Jianyong Yuan

Tetrahedron

DOI

2021

Discovery of 2,4-pyrimidinediamine derivatives as potent dual inhibitors of ALK and HDAC

Tao Pan, Yan Rong Dan, Dafeng Guo, Junhao Jiang, Dongzhi Ran, Lin Zhang, Binghua Tian, Jianyong Yuan, Yu Yu, Zongjie Gan

European Journal of Medicinal Chemistry

DOI

2021

N-Heterocyclic carbene palladium (II)-pyridine (NHC-Pd (II)-Py) complex catalyzed heck reactions

Dan Li, Qingqiang Tian, Xuetong Wang, Qiang Wang, Yin Wang, Siwei Liao, Ping Xu, Xin Huang, Jianyong Yuan

Synthetic Communications

DOI

2021

Catalyst-free and eco-friendly synthesis of masked haloarylboronic acids R (alkyl or aryl)-B(dan) on water

Siwei Liao, Xueyuan Hu, Yanwu Li, Xuetong Wang, Dan Li, Qiang Wang, Yin Wang, Xin Huang, Ping Xu, Huili Wu, Xianliang Li, Jianyong Yuan

Tetrahedron

DOI

2021

A series of new polycyclic carbamoyl pyridone analogues were synthesized by using chloroacetaldehyde as a substrate

Qiang Wang, Xueyuan Hu, Qiulin Kuang, Dan Li, Huili Wu, Jianyong Yuan

Tetrahedron

DOI

2020

Imidazolium chloride as an additive for synthesis of 4(3H)-quinazolinones using anthranilamides and DMF derivatives

Xuetong Wang, Suqin Shang, Qingqiang Tian, Yin Wang, Huili Wu, Zhiyao Li, Shangjun Zhou, Heng Liu, Zeshu Dai, Wen Luo, Dan Li, Xin Xiao, Shuqi Wang, Jianyong Yuan

Tetrahedron

DOI

2020

A KHSO4 promoted tandem synthesis of 1,3,4-thiadiazoles from thiohydrazides and DMF derivatives

Zongjie Gan, Binghua Tian, Jianyong Yuan, Dongzhi Ran, Lin Zhang, Gang Dong, Tao Pan, Yixin Zeng, Yu Yu

Tetrahedron Letters

DOI

2019

TiCl4 mediated facile synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles

Lin Zhang, Yu Yu, Qiang Tang, Jianyong Yuan, Dongzhi Ran, Binghua Tian, Tao Pan, Zongjie Gan

Synthetic Communications

DOI

2019

Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles

Zeshu Dai, Qingqiang Tian, Yanwu Li, Suqin Shang, Wen Luo, Xuetong Wang, Dan Li, Ying Zhang, Zhiyao Li, Jianyong Yuan

Molecules

DOI

2019

Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride

Qingqiang Tian, Wen Luo, Zongjie Gan, Dan Li, Zeshu Dai, Huajun Wang, Xuetong Wang, Jianyong Yuan

Molecules

DOI

2018

苯甲酸衍生物类神经氨酸酶抑制剂的合成及活性评价

王敬，袁建勇，刘盼和，胡叶敏，李雁武

《精细化工》

2018

Imidazolium chloride-catalyzed synthesis of benzimidazoles and 2-substituted benzimidazoles from o-phenylenediamines and DMF derivatives

Zongjie Gan, Qingqiang Tian, Suqin Shang, Wen Luo, Zeshu Dai, Huajun Wang, Dan Li, Xuetong Wang, Jianyong Yuan

Tetrahedron

DOI

2018

Imidazolium Chloride: An Efficient Catalyst for Transamidation of Primary Amines

Qingqiang Tian, Zongjie Gan, Xuetong Wang, Dan Li, Wen Luo, Huajun Wang, Zeshu Dai, Jianyong Yuan

Molecules

DOI

2018

Synthesis and characterization of four process impurities in pazopanib

Jianyong Yuan, Di Zhang, Xiangnan Hu, Huajun Wang, Dongzhi Ran, Su-Qing Shang, Zongjie Gan

Die Pharmazie

DOI

2017

一种新型苯甲酸衍生物类神经氨酸酶抑制剂的合成及体外酶抑制活性

王敬，刘盼和，袁建勇，李雁武

《中国医药工业杂志》

2017

拉帕替尼新中间体的合成

郭卿，李雁武，任学状，袁建勇

《化学通报(中英文)》

2017

中性条件下亚氯酸钠和双氧水氧化芳香醛

田青强，王华均，袁建勇

《化学通报(中英文)》

2017

Halogen–Metal Exchange on Bromoheterocyclics with Substituents Containing an Acidic Proton via Formation of a Magnesium Intermediate

Qingqiang Tian, Suqin Shang, Huajun Wang, Guoqiang Shi, Zhiyao Li, Jianyong Yuan

Molecules

DOI

2017

Low-Pressure Selectivity, Stepwise Gas Sorption Behaviors, and Luminescent Properties (Experimental Findings and Theoretical Correlation) of Three Zn(II)-Based Metal–Organic Frameworks

Yun-Long Wu, Fan Yang, J. Qian, Guo-Ping Yang, Jing Jin, H. Miao, Jianyong Yuan, Yao-Yu Wang

DOI

2016

一种电压门控钠通道配体的合成及其体外生物活性评价

刘盼和，袁建勇，胡叶敏，王敬，李雁武

《中国医药工业杂志》

2016

用次氯酸钙处理含甲醛废液研究

卜鑫珏，王驰，袁建勇，任学状，靳红卫

《化工时刊》

2016

Pazopanib dimer and preparing method and application thereof

Jianyong Yuan, Guo-Qing Tu, Li-Ping Zhou, Yan-Wu Li, Qing-Qiang Tian, Hua-Jun Wang

2015

醋酸特拉司酮的合成

任学状，李雁武，郭卿，袁勇，袁建勇

《化学通报(中英文)》

2015

并联双噻吩化合物的合成研究进展

袁勇，李雁武，李伦，朱太勇，袁建勇

《化学试剂》

2015

利胆药3,3'-二羟基二丁醚的一种简单合成方法

朱太勇，袁建勇，谢宝刚，李雁武

《化学试剂》

2015

4-(4-氨基苯基)-3-吗啉酮的合成

刘凯，袁建勇，李伦，袁勇，朱太勇，李雁武

《化学研究与应用》

2015

一种N-甲基氨基酸酯的合成方法

袁勇，李雁武，李伦，袁建勇

《化学研究与应用》

2015

厄洛替尼关键中间体的合成

李伦，李雁武，袁勇，袁建勇

《化学研究与应用》

2015

Microwave-Assisted Synthesis of Fused Piperazine-Benzimidazoles via a Facile, One-Pot Procedure.

Gui-Ting Song, Shi-qiang Li, Zhi-Wei Yang, Jianyong Yuan, Ming-Shu Wang, Jin Zhu, Zhong-Zhu Chen, Zhi-Gang Xu

DOI

2014

A Novel Synthesis of the Oxazolidinone Antithrombotic Agent Rivaroxaban

Jianyong Yuan, Kai Liu, Lun Li, Yong Yuan, Xuelei Liu, Yanwu Li

Molecules

DOI

2013

A facile synthesis of the oxazolidinone antibacterial agent linezolid

Yanwu Li, Yan Liu, Yun-Can Jia, Jianyong Yuan

Chinese Chemical Letters

DOI

2010

多西他赛合成工艺

徐少杰，袁建勇，周辉，甘勇军，李勤耕

《科技导报》

2009

替考拉宁及间甲基苯基异氰酸酯替考拉宁手性固定相的对映体分离能力评价与比较

沈报春，袁建勇，徐贝佳，徐秀珠

《化学学报》

2008

3种芳氧苯氧丙酸类除草剂在CDMPC与万古霉素手性固定相上的对映体分离

沈报春，袁建勇，王恒春，徐贝佳，徐秀珠

《分析测试学报》

2008

二茂铁衍生物在Chiralpak AD手性固定相上的对映体分离及热力学性质

沈报春，袁建勇，王恒春，徐贝佳，徐秀珠

《理化检验-化学分册》

2007

烯二炔类抗肿瘤抗生素全合成研究V. 通过分子内的偶联反应合成十元环状烯二炔

袁建勇，郭慧元，李卓荣，张致平

《中国抗生素杂志》

2006

毒三素链霉菌发酵产物中有关物质的结构鉴定

谭晓世，王栋海，王，陈代杰，袁建勇

《药学与临床研究》

2005

由Valiolamine制备伏格列波糖

吕春雷，叶伟东，胡三明，潘亚金，袁建勇

《中国医药工业杂志》

2001

阻抑动力学光度法测定痕量铜

龙莉，袁建勇，徐其亨

《冶金分析》

2000

烯二炔类抗肿瘤抗生素全合成研究.含芳环烯二炔单元开链衍生物的合成

袁建勇，郭惠元，李卓荣，张致平

《中国医药工业杂志》

2000

烯二炔类抗肿瘤抗生素全合成研究 Ⅲ.十元环状烯二炔单元开链衍生物的合成

袁建勇，郭惠元，李卓荣，张致平

《中国抗生素杂志》

2000

新型降血胆固醇的物质MonacolinK的质谱研究

余志立，袁建勇

《质谱学报》

精选作品

期刊论文

I2–DMSO-Mediated In Situ Capture of Ketenimine Cations by Two Molecules of 3-Aminoindazole for the Synthesis of 1-(1 H -Indazol-3-yl)-2,4-Diphenyl-1 H -Pyrrolo[2′,3′:4,5]Pyrimido[1,2- b ]Indazole Derivatives

Iron-catalyzed synthesis of 4-arylpyrimido[1,2-b]indazoles using 3-aminobenzindazole, phenylacetylene, and N,N-dimethylformamide as one-carbon synthon

I2-DMSO-Mediated Three-Component Cyclization of 2-Aminobenzimidazole to Access 2,3-Substituted Benzo[4,5]imidazo[1,2-a]pyrimidine Derivatives

I 2 -DMSO-mediated [4 + 2] cyclization of methyl ketone with 2-aminobenzimidazole to construct 2,4-disubstituted benzo[4,5]imidazo[1,2- a ] pyrimidines

A Metal-Free Strategy for the Synthesis of Symmetrical 2,3,5,6-Tetrasubstituted Pyridines Using Triethyl Orthoformate as a Carbon Source

Theoretical insights into the radical scavenging performance of common anti-agers from both kinetic and thermodynamic perspectives

Synthesis of Substituted of Benzo[4,5]imidazo[1,2-a]pyrimidines through (3 + 2+1) Cyclization of 2-Aminobenzimidazole, Acetophenone, and N,N-Dimethylformamide as One-Carbon Synthon

A metal-free and additive-free facile method for the synthesis of 1H-Perimidines

One-pot Synthesis of 2,3-disubstituted-4(3H)-quinazolinone from o-aminobenzoic Acid and DMF Derivatives using Imidazole Hydrochloride as a Promoter

A Metal-Free strategy for the synthesis of tetrasubstituted Pyridines: Dimethyl sulfoxide as carbon source

A rapid construction of 1,3,2-benzodiazaborininones [R–B(aam)] from boronic acids and anthranilamides

Iron-Catalyzed [2+1+2+1] Annulation of Amines and N , N -Dimethyl Enaminones using N , N -Dimethylaminoethanol as a One-Carbon Synthon for the Synthesis of 1,4-Dihydropyridines

Pyridine hydrochloride-promoted C C bond cleavage approach: A metal-free and peroxide-free facile method for the synthesis of amide derivatives

Ionic melting salt imidazole hydrochloride mediated the decarboxylation of (hetero)aromatic carboxylic acids

Imidazole Hydrochloride Promoted Synthesis of Nitriles from Aldehydes

Imidazolium chloride as an additive for synthesis of perimidines using 1,8-diaminonaphthalene and DMF derivatives

A rapid construction of new boron heterocycles and evaluation of photophysical properties of iminoboronates

Discovery Studio软件在药物化学教学中的应用

Imidazole hydrochloride promoted synthesis of 3,5-disubstituted-1,2,4-oxadiazoles

Discovery of 2,4-pyrimidinediamine derivatives as potent dual inhibitors of ALK and HDAC

N-Heterocyclic carbene palladium (II)-pyridine (NHC-Pd (II)-Py) complex catalyzed heck reactions

Catalyst-free and eco-friendly synthesis of masked haloarylboronic acids R (alkyl or aryl)-B(dan) on water

A series of new polycyclic carbamoyl pyridone analogues were synthesized by using chloroacetaldehyde as a substrate

Imidazolium chloride as an additive for synthesis of 4(3H)-quinazolinones using anthranilamides and DMF derivatives

A KHSO4 promoted tandem synthesis of 1,3,4-thiadiazoles from thiohydrazides and DMF derivatives

TiCl4 mediated facile synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles

Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles

Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride

苯甲酸衍生物类神经氨酸酶抑制剂的合成及活性评价

Imidazolium chloride-catalyzed synthesis of benzimidazoles and 2-substituted benzimidazoles from o-phenylenediamines and DMF derivatives

Imidazolium Chloride: An Efficient Catalyst for Transamidation of Primary Amines

Synthesis and characterization of four process impurities in pazopanib

一种新型苯甲酸衍生物类神经氨酸酶抑制剂的合成及体外酶抑制活性

拉帕替尼新中间体的合成

中性条件下亚氯酸钠和双氧水氧化芳香醛

Halogen–Metal Exchange on Bromoheterocyclics with Substituents Containing an Acidic Proton via Formation of a Magnesium Intermediate

Low-Pressure Selectivity, Stepwise Gas Sorption Behaviors, and Luminescent Properties (Experimental Findings and Theoretical Correlation) of Three Zn(II)-Based Metal–Organic Frameworks

一种电压门控钠通道配体的合成及其体外生物活性评价

用次氯酸钙处理含甲醛废液研究

Pazopanib dimer and preparing method and application thereof

醋酸特拉司酮的合成

并联双噻吩化合物的合成研究进展

利胆药3,3'-二羟基二丁醚的一种简单合成方法

4-(4-氨基苯基)-3-吗啉酮的合成

一种N-甲基氨基酸酯的合成方法

厄洛替尼关键中间体的合成

Microwave-Assisted Synthesis of Fused Piperazine-Benzimidazoles via a Facile, One-Pot Procedure.

A Novel Synthesis of the Oxazolidinone Antithrombotic Agent Rivaroxaban

A facile synthesis of the oxazolidinone antibacterial agent linezolid

多西他赛合成工艺

替考拉宁及间甲基苯基异氰酸酯替考拉宁手性固定相的对映体分离能力评价与比较

3种芳氧苯氧丙酸类除草剂在CDMPC与万古霉素手性固定相上的对映体分离

二茂铁衍生物在Chiralpak AD手性固定相上的对映体分离及热力学性质

烯二炔类抗肿瘤抗生素全合成研究V. 通过分子内的偶联反应合成十元环状烯二炔

毒三素链霉菌发酵产物中有关物质的结构鉴定

由Valiolamine制备伏格列波糖

阻抑动力学光度法测定痕量铜

烯二炔类抗肿瘤抗生素全合成研究.含芳环烯二炔单元开链衍生物的合成

烯二炔类抗肿瘤抗生素全合成研究 Ⅲ.十元环状烯二炔单元开链衍生物的合成

新型降血胆固醇的物质MonacolinK的质谱研究