孙进｜沈阳药科大学｜学者主页

2026

溶瘤微生物制剂：临床前研究与临床进展

凌昊，章浩天，何仲贵，孙孟驰，孙进

《药学进展》

DOI

2026

纳米材料用于癌症饥饿疗法的研究进展（英文）

史健斌，崔继丹，孙新新，孙进，何仲贵，罗聪，张申武

Science China Materials

2025

重组人胸腺素β4滴眼液蛋白含量反相高效液相色谱检测方法的建立及验证

张波，王艺诺，孙进

《中国生物制品学杂志》

DOI

2025

基于人工智能设计的载药细菌外膜囊泡用于体外激活树突状细胞的研究

谢东轩，东玉灏，何仲贵，孙进，孙孟驰

《药学学报》

2025

血小板在肿瘤发展中的动态作用及以其为基础的治疗手段

路奇，杜莉莉，孙进

《中国临床药理学与治疗学》

2023

Ying-Chao Li, Yong-Jun Wang, Ran Zhang, Cui-Ru Liu, Yue Wei, Jin Sun, Zhong-Gui He, Youjun Xu, Tianhong Zhang

Drug Delivery and Translational Research

DOI

2017

胃肠道生物黏附给药系统的研究进展

刘岩，刘荣钲，孙进

《中南药学》

2017

DOI

2017

循環時間の延長と強化された抗腫瘍活性を有する迅速アルブミン結合5‐フルオロウラシルプロドラッグ【Powered by NICT】

Dong-Yang Zhao, Huicong Zhang, Wenhui Tao, Wei Wei, Jin Sun, Zhong-Gui He

2016

HPLC法测定盐酸普拉克索平衡溶解度和表观油水分配系数

杨滨，马攀勤，孙进，夏欣，仵明瑞

《中国药剂学杂志(网络版)》

2016

International journal of pharmaceutics

DOI

Q. Fu, Xiaonan Su, Yanxian Hou, Mo Li, Jing-Ru Li, Jin Sun, Zhong-Gui He

DOI

2016

Self-Assembled Redox Dual-Responsive Prodrug-Nanosystem Formed by Single Thioether-Bridged Paclitaxel-Fatty Acid Conjugate for Cancer Chemotherapy

Cong Luo, Jin Sun, Dan Liu, Bing-Jun Sun, Lei Miao, S. Musetti, Jing Li, Xiao-Peng Han, Yuqian Du, Lin Li, Leaf Huang, Zhong-Gui He

Nano letters (Print)

DOI

2016

強力な化学療法ナノ医療としての小分子オレイン酸プロドラッグの腫瘍酸化還元感受性ナノ集合体の容易な作製【Powered by NICT】

Cong Luo, Jin Sun, Bing-Jun Sun, Dan Liu, Lei Miao, Goodwin Tyler Jay, H. Leaf, Zhong-Gui He

2016

Zhen-Bao Li, Xiao-Peng Han, Yinglei Zhai, He Lian, Dong Zhang, Wenjuan Zhang, Yong-Jun Wang, Zhong-Gui He, Zheng Liu, Jin Sun

Colloids and Surfaces B: Biointerfaces

DOI

2015

Preparation of glutamic acid-TPGS block copolymer and application thereof to targeted drug delivery

Jin Sun, Zhong-Gui He, Lin Li, Xing-Sheng Di

Jing-Min Wang, Ying-Hua Sun, Bo Li, Rui Fan, Bing Li, Teng-Rui Yin, L. Rong, Jin Sun

DOI

2015

Recent Advances in Platinum (IV) Complex‐Based Delivery Systems to Improve Platinum (II) Anticancer Therapy

Xiao-Peng Han, Jin Sun, Yong-Jun Wang, Zhong-Gui He

Medicinal research reviews (Print)

DOI

2015

Multifunctional Poly(methyl vinyl ether-co-maleic anhydride)-graft-hydroxypropyl-β-cyclodextrin Amphiphilic Copolymer as an Oral High-Performance Delivery Carrier of Tacrolimus.

Dong Zhang, Xiaolei Pan, Shang Wang, Yinglei Zhai, Jibin Guan, Q. Fu, Xiaoli Hao, Wan-Peng Qi, Yingli Wang, He Lian, Xiaohong Liu, Yong-Jun Wang, Ying-Hua Sun, Zhong-Gui He, Jin Sun

Molecular Pharmaceutics

DOI

2015

Nanomicelles based on X-shaped four-armed peglyated distearylglycerol as long circulating system for doxorubicin delivery.

Wenping Zhang, Jin Sun, Wu-Hong Fang, Xiaoyu Ai, Cui-Fang Cai, Yilin Tang, Xiaonan Su, Zhi Feng, Yan Liu, Mengying Tao, Xiao-Dan Yan, Guoliang Chen, Zhong-Gui He

European Journal of Pharmaceutical Sciences

DOI

2015

Menglin Wang, Jin Sun, Yinglei Zhai, He Lian, Cong Luo, Lin Li, Yuqian Du, Dong Zhang, Wenya Ding, Shuhong Qiu, Yu-Hai Liu, Long-Fa Kou, Xiang-Fei Han, Rongwu Xiang, Yong-Jun Wang, Zhong-Gui He

Biomacromolecules

DOI

2014

乳化溶剂挥发法制备紫杉醇PLGA纳米粒及其体外评价

寇龙发，高利芳，姚情，李东坡，孙进

《中国药剂学杂志(网络版)》

2014

RP-HPLC法测定他克莫司聚酸酐纳米制剂中他克莫司的含量

张栋，潘小磊，王尚，关吉斌，孙进

《中国药剂学杂志(网络版)》

2014

Micronized glibenclamide and composition thereof

Jin Sun, Pan-Qin Ma, Ya-Jun Yang, Xiaohong Liu, Yong-Jun Wang

Le Sun, Wei-xi Zhang, Xiaohong Liu, Jin Sun

DOI

2014

Star-shape redox-responsive PEG-sheddable copolymer of disulfide-linked polyethylene glycol-lysine-di-tocopherol succinate for tumor-triggering intracellular doxorubicin rapid release: head-to-head comparison.

Xiaoyu Ai, Jin Sun, Lu Zhong, Chunnuan Wu, Handong Niu, Tao Xu, He Lian, Xiao-Peng Han, Guolian Ren, Wenya Ding, Jia Wang, Xiao-Hui Pu, Zhong-Gui He

Macromolecular Bioscience

DOI

2014

PepT1, ASBT-Linked Prodrug Strategy to Improve Oral Bioavailability and Tissue Targeting Distribution.

Xiao-Peng Han, Jin Sun, Yong-Jun Wang, Zhong-Gui He

Current drug metabolism

DOI

2014

Yuqian Du, Yinglei Zhai, Ju-Hong Zhang, Chunnuan Wu, Cong Luo, Jin Sun, Zhong-Gui He

DOI

2013

Xiaohong Liu, Guang-Jin Li, Jun-Feng Wang, Jin Sun, Si Chen, Bing Li, Zhong-Gui He

2013

Development of a Supercritical Fluid Chromatography-Tandem Mass Spectrometry Method for the Determination of Azacitidine in Rat Plasma and Its Application to a Bioavailability Study

Dong-Po Li, Tianhong Zhang, Long-Fa Kou, Youxi Zhang, Jin Sun, Zhong-Gui He

Molecules

DOI

2013

Jin Sun, Zhong-Gui He, Xiao-Peng Han, Tianhong Zhang

2013

Design and evaluation of enteric-coated tablets for rifampicin and isoniazid combinations

Yong-Jun Wang, Hong-Zhuo Liu, Kai Liu, Jin Sun, Zhong-Gui He

Pharmaceutical development and technology (Print)

DOI

2013

Enhanced oral delivery of paclitaxel using acetylcysteine functionalized chitosan-vitamin E succinate nanomicelles based on a mucus bioadhesion and penetration mechanism.

Ying Kong, Yong-Bing Sun, Meng Zhu, Youxi Zhang, Jin Sun, Zhong-Gui He, Tianhong Zhang

2012

Gui-Xia Ling, Peng Zhang, Jin Sun, Wenping Zhang, Q. Fu, Tianhong Zhang, Yi-Hui Deng, Zhong-Gui He

Biomedical chromotography

DOI

2010

超临界流体制备纳米药物的研究进展

多西他赛纳米脂质载体的制备及其性质考察

杨平，孙进，刘凯，常笛，赵焰平，何仲贵

肺泡巨噬细胞单层模型在生物药剂学中的应用

孙进，出口芳春，陈济民，张汝华，森本一洋

《实用药物与临床》

精选作品

期刊论文

溶瘤微生物制剂：临床前研究与临床进展

纳米材料用于癌症饥饿疗法的研究进展（英文）

重组人胸腺素β4滴眼液蛋白含量反相高效液相色谱检测方法的建立及验证

基于人工智能设计的载药细菌外膜囊泡用于体外激活树突状细胞的研究

血小板在肿瘤发展中的动态作用及以其为基础的治疗手段

纳米药物毒性效应机制和安全性评价

Emerging photodynamic nanotherapeutics for inducing immunogenic cell death and potentiating cancer immunotherapy.

Synergetic lethal energy depletion initiated by cancer cell membrane camouflaged nano-inhibitor for cancer therapy

Molecular recognition-driven supramolecular nanoassembly of a hydrophobic uracil prodrug and hydrophilic cytarabine for precise combination treatment of solid and non-solid tumors.

Monensin Enhanced Generation of Extracellular Vesicles as Transfersomes for Promoting Tumor Penetration of Pyropheophorbide-a from Fusogenic Liposome.

临床药学专业学位研究生培养模式的现状分析与思考

纳米注射剂仿制药的药学技术要求

基于马来酰亚胺基团的肠道黏附纳米粒对改善药物口服生物利用度的研究

肿瘤氧化还原微环境智能响应型前药纳米组装体的研究进展

Apoptotic body–mediated intercellular delivery for enhanced drug penetration and whole tumor destruction

Bacteria-Mediated Synergistic Cancer Therapy: Small Microbiome Has a Big Hope

Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration.

Elaborately Engineering a Self‐Indicating Dual‐Drug Nanoassembly for Site‐Specific Photothermal‐Potentiated Thrombus Penetration and Thrombolysis

Smart transformable nanomedicines for cancer therapy.

Erythrocyte membrane-camouflaged carrier-free nanoassembly of FRET photosensitizer pairs with high therapeutic efficiency and high security for programmed cancer synergistic phototherapy

Probing the fluorination effect on the self-assembly characteristics, in vivo fate and antitumor efficacy of paclitaxel prodrug nanoassemblies

Minor change in the length of carbon chain has a great influence on the antitumor effect of paclitaxel-fatty alcohol prodrug nanoassemblies: Small roles, big impacts

Small-Molecule Prodrug Nanoassemblies: An Emerging Nanoplatform for Anticancer Drug Delivery.

盐酸普拉克索片制备及影响因素考察

HPLC法测定匹多莫德原料药中7种有关物质

Pure redox-sensitive paclitaxel–maleimide prodrug nanoparticles: Endogenous albumin-induced size switching and improved antitumor efficiency

Nanosponges of circulating tumor-derived exosomes for breast cancer metastasis inhibition.

Trisulfide bond–mediated doxorubicin dimeric prodrug nanoassemblies with high drug loading, high self-assembly stability, and high tumor selectivity

A computer-aided chem-photodynamic drugs self-delivery system for synergistically enhanced cancer therapy

Nanotherapeutics for Antimetastatic Treatment.

Single-ligand dual-targeting irinotecan liposomes: control of targeting ligand display by pH-responsive PEG-shedding strategy to enhance tumor-specific therapy and attenuate toxicity.

Emerging nanotherapeutics for antithrombotic treatment.

An exosome-like programmable-bioactivating paclitaxel prodrug nanoplatform for enhanced breast cancer metastasis inhibition.

Emerging carrier-free nanosystems based on molecular self-assembly of pure drugs for cancer therapy.

Intestinal OCTN2- and MCT1-targeted drug delivery to improve oral bioavailability

Quercetin amorphous solid dispersions prepared by hot melt extrusion with enhanced solubility and intestinal absorption

Light-triggered dual-modality drug release of self-assembled prodrug-nanoparticles for synergistic photodynamic and hypoxia-activated therapy.

Dimeric prodrug-based nanomedicines for cancer therapy.

Ferroptosis-driven nanotherapeutics for cancer treatment.

OCTN2-targeted nanoparticles for oral delivery of paclitaxel: differential impact of the polyethylene glycol linker size on drug delivery in vitro, in situ, and in vivo

Recent progress of hypoxia-modulated multifunctional nanomedicines to enhance photodynamic therapy: opportunities, challenges, and future development

Endocytosis of ATB0,+(SLC6A14)-targeted liposomes for drug delivery and its therapeutic application for pancreatic cancer

Special topic: Emerging role of transporters in drug interaction and delivery

Cytochrome P450 enzyme-mediated auto-enhanced photodynamic cancer therapy of co-nanoassembly between clopidogrel and photosensitizer

Probing the Superiority of Diselenium Bond on Docetaxel Dimeric Prodrug Nanoassemblies: Small Roles Taking Big Responsibilities.

缬沙坦片的溶出方法学研究

A novel oral prodrug-targeting transporter MCT 1: 5-fluorouracil-dicarboxylate monoester conjugates

Formulating a single thioether-bridged oleate prodrug into a self-nanoemulsifying drug delivery system to facilitate oral absorption of docetaxel.

In vivo irreversible albumin-binding near-infrared dye conjugate as a naked-eye and fluorescence dual-mode imaging agent for lymph node tumor metastasis diagnosis.

Oxidation-strengthened disulfide-bridged prodrug nanoplatforms with cascade facilitated drug release for synergetic photochemotherapy

Redox dual-responsive paclitaxel-doxorubicin heterodimeric prodrug self-delivery nanoaggregates for more effective breast cancer synergistic combination chemotherapy.

Efficient Intestinal Digestion and On Site Tumor‐Bioactivation are the Two Important Determinants for Chylomicron‐Mediated Lymph‐Targeting Triglyceride‐Mimetic Docetaxel Oral Prodrugs

Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy

In situ apolipoprotein E-enriched corona guides dihydroartemisinin-decorating nanoparticles towards LDLr-mediated tumor-homing chemotherapy

Self-facilitated ROS-responsive nanoassembly of heterotypic dimer for synergistic chemo-photodynamic therapy.

Corrigendum to 'A surfactant-like chemotherapeutic agent as a nanocarrier for delivering photosensitizers against cancer: A facile drug-delivering-drug strategy' [Int. J. Pharm. 562 (2019) 313-320].

Self-Strengthened Oxidation-Responsive Bioactivating Prodrug Nanosystem with Sequential and Synergistically Facilitated Drug Release for Treatment of Breast Cancer.

High Co-loading Capacity and Stimuli-Responsive Release Based on Cascade Reaction of Self-Destructive Polymer for Improved Chemo-Photodynamic Therapy.

Monocarboxylate transporter 1: A promising drug-delivery target in the treatment of brain diseases and cancers.

Photodynamic PEG-coated ROS-sensitive prodrug nanoassemblies for core-shell synergistic chemo-photodynamic therapy.

A surfactant-like chemotherapeutic agent as a nanocarrier for delivering photosensitizers against cancer: A facile drug-delivering-drug strategy.

A facile di-acid mono-amidation strategy to prepare cyclization-activating mono-carboxylate transporter 1-targeting gemcitabine prodrugs for enhanced oral delivery.

Bioinspired nanoplatelets for chemo-photothermal therapy of breast cancer metastasis inhibition.

Polydopamine-modified ROS-responsive prodrug nanoplatform with enhanced stability for precise treatment of breast cancer

Probing a dipeptide-based supramolecular assembly as an efficient camptothecin delivering carrier for cancer therapy: computational simulations and experimental validations.

Insight into the preformed albumin corona on in vitro and in vivo performances of albumin-selective nanoparticles

Regulating the alky chain length of fatty acid-didanosine prodrugs and evaluating its role in albumin binding

Self-Assembly of a Pure Photosensitizer as a Versatile Theragnostic Nanoplatform for Imaging-Guided Antitumor Photothermal Therapy.

Multifunctional Tumor-Targeting Cathepsin B-Sensitive Gemcitabine Prodrug Covalently Targets Albumin in Situ and Improves Cancer Therapy.

Cytosine arabinoside prodrug designed to bind plasma serum albumin for drug delivery

Covalently mucoadhesive amphiphilic prodrug of 5-fluorouracil for enhanced permeation and improved oral absorption

Precisely albumin‐hitchhiking tumor cell‐activated reduction/oxidation‐responsive docetaxel prodrugs for the hyperselective treatment of breast cancer

Intestinal absorption and activation of decitabine amino acid ester prodrugs mediated by peptide transporter PEPT1 and enterocyte enzymes.

Transformative hyaluronic acid-based active targeting supramolecular nanoplatform improves long circulation and enhances cellular uptake in cancer therapy

Light-activatable dual-source ROS-responsive prodrug nanoplatform for synergistic chemo-photodynamic therapy.

Amino functionalized chiral mesoporous silica nanoparticles for improved loading and release of poorly water-soluble drug

Impact of HPMC on inhibiting crystallization and improving permeability of curcumin amorphous solid dispersions.

Dipeptide-modified nanoparticles to facilitate oral docetaxel delivery: new insights into PepT1-mediated targeting strategy