孙涛｜南开大学｜学者主页

2026

ROS-autocatalytic nanoplatform interfering astrocyte-cancer crosstalk and enhancing glioblastoma therapy

Yun Chen, Zong-Hua Tian, Hong-Rui Fan, Jing-Yi Zhou, Shi-Lin Zhang, Xu-Wen Li, Bo-Yu Su, Chen Jiang, Tao Sun

Nature Communications

2026

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

Jia-Wen Chen, Haoyu You, He-Fa Huang, Huihui Chai, Ruize Zhu, Yun Guan, Qisheng Tang, Tian-Wen Li, Shan Jiang, Houshi Xu, Peng Wang, Yue Wang, Maoyuan Sun, Beining Liu, Zhen Li, Yulai Zeng, Weiqiu Ping, Yanlin Teng, Song Yan, Qinghui Li, Long Gu, Tao Sun, Zhi-feng Shi

Advancement of science

精选作品

期刊论文

ROS-autocatalytic nanoplatform interfering astrocyte-cancer crosstalk and enhancing glioblastoma therapy

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

Reengineered Albumin-Paclitaxel Nanoparticles Remodeling Tumor Cell Death Pathways for Prevention of Chemotherapy-Induced Breast Cancer Metastasis.

Disulfidptosis-mediated antitumor therapy: From molecular basis to engineered delivery systems

AI‐Optimized 3D‐Printed Dual‐Layer Implant: Resolving Chemo‐Immunotherapy Sequential Administration Dilemma for Colorectal Cancer Peritoneal Metastasis

综合运动康复方案对康复期乳腺癌术后患者上肢功能、生活质量的影响

抗体偶联药物治疗HER2阳性晚期乳腺癌的研究新进展

FDX1-short proteoform induces caspase-independent cell death in tumor cells

Apoptotic body-encapsulated zinc-doped Salvia miltiorrhiza carbon dots trigger PANoptosis for targeted therapy of hepatocellular carcinoma

Engineered Bacterial Outer Membrane Vesicles‐Based Doxorubicin and CD47‐siRNA Co‐Delivery Nanoplatform Overcomes Immune Resistance to Potentiate the Immunotherapy of Glioblastoma

A Supramolecular Nanoscavengers: Based “Cargo‐Exchange” Breaking Cholesterol Metabolic Dysregulation for Glioblastoma Therapy

Mitocytosis-inducing nanoparticles alleviate gemcitabine resistance via dual disruption of pyrimidine synthesis and redox homeostasis in pancreatic ductal adenocarcinoma.

Disrupting Tumor Lactate Homeostasis to Sensitize Chemo-Immunotherapy Using a Glucose-Disguised Lactate Interceptor.

Manganese-based virus-mimicking nanomedicine with triple immunomodulatory functions inhibits breast cancer brain metastasis.

Liquid-liquid phase separation mediated order and pathological chaos: From cellular organization to precision modulating.

A Methionine Allocation Nanoregulator for the Suppression of Cancer Stem Cells and Support to the Immune Cells by Epigenetic Regulation

Polymer-engineered PROTAC nanovehicles amplify synergistic effects with temozolomide by BRD4 degradation.

Transcytosis-Triggering Nanoparticles for Overcoming Stromal Barriers and Reversing Immunosuppression in Pancreatic Cancer Combinatorial Therapy.

Shutting Down the ‘Language Encoder’: A Pathogen‐Derived Nano‐Interferer Disrupt Sialylation Metabolism and Reprogram Intercellular Communication in Glioblastoma

乳腺癌靶向治疗新挑战:抗体偶联药物相关心脏毒性的发生机制与临床管理

吡洛西利单药治疗经多线抗肿瘤治疗失败的HR+/HER2-乳腺癌患者的开放标签、单臂、多中心Ⅱ期研究：BRIGHT-1研究

Magnetic sculpture-like tumor cell vaccines enable targeted in situ immune activation and potent antitumor effects

Biomimetic carbon nanopolymers ANM-NPs act on mannose receptors and complement receptors to promote tumor antigen presentation

Retraction Note: Polyphyllin I suppresses the formation of vasculogenic mimicry via Twist1/VE-cadherin pathway

Extrachromosomal DNA biogenesis is dependent on DNA looping and religation by YY1-Lig3-PARylation complex

Glycated ECM Derived Carbon Dots Inhibit Tumor Vasculogenic Mimicry by Disrupting RAGE Nuclear Translocation and Its Interaction With HMGB1 (Adv. Mater. 24/2025)

Glycated ECM Derived Carbon Dots Inhibit Tumor Vasculogenic Mimicry by Disrupting RAGE Nuclear Translocation and Its Interaction With HMGB1

Correction: MSC microvesicles loaded G-quadruplex-enhanced circular single-stranded DNA-9 inhibits tumor growth by targeting MDSCs

Suppression of Sepsis Cytokine Storm by Escherichia Coli Cell Wall‐Derived Carbon Dots (Adv. Mater. 12/2025)

Suppression of Sepsis Cytokine Storm by Escherichia Coli Cell Wall‐Derived Carbon Dots

Rbfox3 Promotes Transformation of MDSC‐Like Tumor Cells to Shape Immunosuppressive Microenvironment

PROTAC delivery in tumor immunotherapy: Where are we and where are we going?

Recent advances in biomimetic strategies for the immunotherapy of glioblastoma.

Therapeutic regulation of epigenetics in cancer treatment through drug delivery systems

乳腺癌抗人表皮生长因子受体2抗体药物偶联物类药物的耐药机制

白细胞衍生性指标联合检测对恶性肿瘤患者化疗后感染的预测价值

AK-HER2与参照药治疗HER2阳性转移性乳腺癌患者的疗效、体内代谢特征、安全性和免疫原性比较：一项多中心、随机、双盲Ⅲ期等效性临床试验

Correction: Knockdown of THOC1 reduces the proliferation of hepatocellular carcinoma and increases the sensitivity to cisplatin

WRN Nuclease‐Mediated EcDNA Clearance Enhances Antitumor Therapy in Conjunction with Trehalose Dimycolate/Mesoporous Silica Nanoparticles

EGR3 Inhibits Tumor Progression by Inducing Schwann Cell‐Like Differentiation

Corrigendum to “Salidroside improves the hypoxic tumor microenvironment and reverses the drug resistance of platinum drugs via HIF-1α signaling pathway” [EBioMedicine 38 (2018) 25–36]

Retraction Note: Hsp90β promotes aggressive vasculogenic mimicry via epithelial–mesenchymal transition in hepatocellular carcinoma

Editorial: Epithelial-mesenchymal transition (EMT) as a therapeutic target in cancer, Volume II

Editorial: Epithelial-mesenchymal transition (EMT) as a therapeutic target in cancer

Intratumor Mycoplasma promotes the initiation and progression of hepatocellular carcinoma

Isorhamnetin and anti-PD-L1 antibody dual-functional mesoporous silica nanoparticles improve tumor immune microenvironment and inhibit YY1-mediated tumor progression

HSF4/COIL complex‐dependent R‐loop mediates ultraviolet‐induced inflammatory skin injury

Live-cell imaging-based dynamic vascular formation assay for antivascular drug evaluation and screening

Twist1-YY1-p300 complex promotes the malignant progression of HCC through activation of miR-9 by forming phase-separated condensates at super-enhancers and relieved by metformin

术前白蛋白与纤维蛋白原比值对三阴性乳腺癌患者的预后影响和临床意义

中国乳腺癌新辅助治疗专家共识(2022年版)

Corrigendum: Doxycycline Inhibits Cancer Stem Cell-Like Properties via PAR1/FAK/PI3K/AKT Pathway in Pancreatic Cancer

Corrigendum: YY1 Promotes Endothelial Cell-Dependent Tumor Angiogenesis in Hepatocellular Carcinoma by Transcriptionally Activating VEGFA

A non‐retinol retinoic acid receptor‐γ (RAR‐γ/NR1B3) selective agonist, tectorigenin, can effectively inhibit the ultraviolet A‐induced skin damage

Chrysin targets myeloid‐derived suppressor cells and enhances tumour response to anti‐PD‐1 immunotherapy

Biomimetic Immunosuppressive Exosomes that Inhibit Cytokine Storms Contribute to the Alleviation of Sepsis

Correction: Thymidine phosphorylase promotes malignant progression in hepatocellular carcinoma through pentose Warburg effect

Psychologic Stress Drives Progression of Malignant Tumors via DRD2/HIF1α Signaling

MTA2 triggered R-loop trans-regulates BDH1-mediated β-hydroxybutyrylation and potentiates propagation of hepatocellular carcinoma stem cells

Doxycycline Inhibits Cancer Stem Cell-Like Properties via PAR1/FAK/PI3K/AKT Pathway in Pancreatic Cancer

XPO1 inhibition synergizes with PARP1 inhibition in small cell lung cancer by targeting nuclear transport of FOXO3a

Corrigendum to “Selenium-lentinan inhibits tumor progression by regulating epithelial-mesenchymal transition” [Toxicol Appl Pharmacol 360 (2018) 1–8]

Microbial metabolite deoxycholic acid promotes vasculogenic mimicry formation in intestinal carcinogenesis

Targeting myeloid-derived suppressor cells to attenuate vasculogenic mimicry and synergistically enhance the anti-tumor effect of PD-1 inhibitor

RETRACTED: Tumor cell-secreted exosomal miR-22-3p inhibits transgelin and induces vascular abnormalization to promote tumor budding

肠道菌群与恶性肿瘤的研究进展

Knockdown of THOC1 reduces the proliferation of hepatocellular carcinoma and increases the sensitivity to cisplatin

Glycyrrhizic Acid-Induced Differentiation Repressed Stemness in Hepatocellular Carcinoma by Targeting c-Jun N-Terminal Kinase 1

Cartilage Oligomeric Matrix Protein promotes epithelial-mesenchymal transition by interacting with Transgelin in Colorectal Cancer

Lentinan-functionalized Selenium Nanoparticles target Tumor Cell Mitochondria via TLR4/TRAF3/MFN1 pathway

Salidroside can target both P4HB-mediated inflammation and melanogenesis of the skin

Potential type 2 diabetes mellitus drug HMPA promotes short‐chain fatty acid production by improving carbon catabolite repression effect of gut microbiota

RNA m6A methylation promotes the formation of vasculogenic mimicry in hepatocellular carcinoma via Hippo pathway

Deglycosylated Azithromycin Targets Transgelin to Enhance Intestinal Smooth Muscle Function

基于cSMART技术检测ctDNA驱动基因突变指导非小细胞肺癌精准治疗的疗效研究

长链非编码RNA AGAP2-AS1对肾细胞癌侵袭转移能力的影响

YY1 Promotes Endothelial Cell-Dependent Tumor Angiogenesis in Hepatocellular Carcinoma by Transcriptionally Activating VEGFA

Interaction between laminin-5γ2 and integrin β1 promotes the tumor budding of colorectal cancer via the activation of Yes-associated proteins