雷爱华｜南华大学｜学者主页

2026

Itaconate as a Potent Regulator of Neutrophil Responses in Host Defence and Inflammation

Chunying Cheng, Zufeng Cheng, Xinran Ye, S Wang, C-Q Yan, Yiran Chen, Jie Li, Rundong Wu, Aihua Lei

Scandinavian Journal of Immunology

2025

Lipid nanoparticle-delivered mRNA vaccine encoding the MOMP of Chlamydia psittaci elicits protective immune responses in BALB/c mice

Buwei Wang, Jian Xiao, Jiewen Wang, Wanying Zhang, Yinqi Jin, Yalan Jiang, Yuqing Chen, Zhangping He, Aihua Lei, Chunxue Lu, Chuan Wang

Microbiology Spectrum

DOI

2025

Correction: ICAM-1 controls development and function of ILC2

Aihua Lei, Qiang Xiao, Gaoyu Liu, Kun Shi, Qiong Yang, Xing Li, Yu-Feng Liu, Hai-Kun Wang, Wei Cai, Y. Guan, Dmitry I. Gabrilovich, Jie Zhou

Journal of Experimental Medicine

DOI

2024

髓系抑制性细胞调节炎症性疾病中Th17应答的研究进展

贺烈娜，何依芳，何花，熊灵铃，龙伟祥，罗英，雷爱华

《中南医学科学杂志》

2024

新生儿期MDSCs免疫调节作用的研究进展

董睿，雷爱华，姚萌，周洁

《生物医学转化》

2024

肺炎支原体黏附蛋白P30研究进展

张汝，左颖颖，李水红，雷爱华

《中南医学科学杂志》

2024

Suppressing neutrophil itaconate production attenuates Mycoplasma pneumoniae pneumonia

Cui Wang, Jun Wen, Zijun Yan, Yujun Zhou, Zhande Gong, Ying Luo, Zhenkui Li, Kang Zheng, Haijun Zhang, Nan Ding, Chuan Wang, Cuiming Zhu, Yimou Wu, Aihua Lei

PLoS Pathogens

DOI

2024

The role of hormones in ILC2 ‐driven allergic airway inflammation

Zhongling Dai, Zhande Gong, Cui Wang, WeiXiang Long, Duo Liu, Haijun Zhang, Aihua Lei

Scandinavian Journal of Immunology

DOI

2023

Total Flavonoids from Camellia oleifera Alleviated Mycoplasma pneumoniae-Induced Lung Injury via Inhibition of the TLR2-Mediated NF-κB and MAPK Pathways

Nan Ding, Aihua Lei, Zhisheng Shi, Lin Xiang, Bo Wei, Yimou Wu

Molecules

DOI

2023

Interferons as negative regulators of ILC2s in allergic lung inflammation and respiratory viral infections

Cui Wang, Zhaoxiang Du, Ranhui Li, Ying Luo, Cuiming Zhu, Nan Ding, Aihua Lei

Journal of Molecular Medicine

DOI

2023

Mycoplasma genitalium Protein of Adhesion Suppresses T Cell Activation via CypA-CaN-NFAT Pathway

Dan Luo, Haodang Luo, Xiaoliang Yan, Aihua Lei, Jun He, Yating Liao, Kailan Peng, Xia Li, Youyuan Ye, Li Chen, Zhuo Zeng, Hua Xiao, Yanhua Zeng

Microbiology Spectrum

DOI

2023

Protective Immunity against Chlamydia psittaci Lung Infection Induced by a DNA Plasmid Vaccine Carrying CPSIT_p7 Gene Inhibits Dissemination in BALB/c Mice

Chuan Wang, Yingqi Jin, Jiewen Wang, Kang Zheng, Aihua Lei, Chunxue Lu, Shuzhi Wang, Yimou Wu

International Journal of Molecular Sciences

DOI

2023

Nitric Oxide-Producing Polymorphonuclear Neutrophils Confer Protection Against Chlamydia psittaci in Mouse Lung Infection

Ying Luo, Cui Wang, Zhaoxiang Du, Chuan Wang, Yimou Wu, Aihua Lei

The Journal of Infectious Diseases

DOI

2023

Lacticaseibacillus caseiCNRZ1874 supplementation promotes M1 alveolar macrophage activation and attenuatesMycoplasma pneumoniaepneumonia

Naiyu Zhang, Wuwei Zeng, Tingfeng Du, Hongjiang Wei, Wei Tian, Yan Meng, Guiting He, Aihua Lei, Cuiming Zhu

Journal of Applied Microbiology

DOI

2022

Treg调控ILC2参与炎症性疾病的研究进展

龚展德，陈昱丞，戴钟玲，刘欣，袁碧晨，罗英，雷爱华

《中国免疫学杂志》

2022

靶向髓系抑制性细胞的药物在肿瘤治疗中的研究进展

米庄，龚展德，张小漩，李雄，杜雪威，雷爱华

《肿瘤学杂志》

2022

Efficacy of Pgp3 vaccination for Chlamydia urogenital tract infection depends on its native conformation

Bo Peng, Shufang Zhong, Yaoqin Hua, Qizheng Luo, Weilei Dong, Chuan Wang, Zhongyu Li, Chunfen Yang, Aihua Lei, Chunxue Lu

Frontiers in Immunology

DOI

2022

DnaJ, a promising vaccine candidate against Ureaplasma urealyticum infection

Fangyi Guo, Yanhong Tang, Wenjun Zhang, Hongxia Yuan, Jing Xiang, Wenyou Teng, Aihua Lei, Ranhui Li, Guozhi Dai

Applied Microbiology and Biotechnology

DOI

2022

The Beneficial Role of Probiotic Lactobacillus in Respiratory Diseases

Tingfeng Du, Aihua Lei, Naiyu Zhang, Cuiming Zhu

Frontiers in Immunology

DOI

2022

Angiotensin II enhances group 2 innate lymphoid cell responses via AT1a during airway inflammation

Gaoyu Liu, Yingying Chen, Ying Wang, Xiao-Hui Deng, Q. Xiao, Lijuan Zhang, Hai-Xu Xu, Xu Han, Aihua Lei, Juan He, Xing Li, Ying-Jiao Cao, Pan Zhou, Chunhui He, Pei-Qiong Wu, Wen-Hui Jiang, Mei-Zhen Tan, Chun Chen, Quan Yang, Liwei Lu, Kai Deng, Zhi Yao, Jie Zhou

Journal of Experimental Medicine

DOI

2021

短链脂肪酸在炎症性肠病中的免疫调节作用

陈玉琼，顾天宇，张思，朱雪婷，雷爱华

《现代免疫学》

2021

Insights Into Host Cell Cytokines in Chlamydia Infection

Wenjing Xiang, Nanyan Yu, Aihua Lei, Xiaofang Li, Shui Tan, Lijun Huang, Zhou Zhou

Frontiers in Immunology

DOI

2021

TFF3 mediates the NF‐κB/COX2 pathway to regulate PMN‐MDSCs activation and protect against necrotizing enterocolitis

Jingping Liu, Qiong Yang, Ziyang Chen, Shuaijun Lv, Jian Tang, Zhe Xing, Mengyu Shi, Aihua Lei, Gang Xiao, Yumei He

European Journal of Immunology

DOI

2021

Biological functions of IL‐17‐producing cells in mycoplasma respiratory infection

Ying Luo, Cheng Li, Zhou Zhou, Zhan-Chao Gong, Cui-Ming Zhu, Aihua Lei

Immunology

DOI

2021

Bilirubin represents a negative regulator of ILC2 in allergic airway inflammation

Juan He, Guan-Min Jiang, Xing Li, Qiang Xiao, Yingying Chen, Hai-Xu Xu, Gaoyu Liu, Aihua Lei, Pan Zhou, Kun Shi, Quan Yang, Meng Zhao, Zhi Yao, Jie Zhou

Mucosal Immunology

DOI

2020

PPARγ enhances ILC2 function during allergic airway inflammation via transcription regulation of ST2

Qiang Xiao, Juan He, Aihua Lei, Haixu Xu, Lijuan Zhang, Pan Zhou, Guanmin Jiang, Jie Zhou

Mucosal Immunology

DOI

2020

GrpE Immunization Protects Against Ureaplasma urealyticum Infection in BALB/C Mice

Yanhong Tang, Fangyi Guo, Aihua Lei, Jing Xiang, Pengqin Liu, Wenyou Ten, Guozhi Dai, Ranhui Li

Frontiers in Immunology

DOI

2020

Role of myeloid cells in the regulation of group 2 innate lymphoid cell‐mediated allergic inflammation

Aihua Lei, Yumei He, Qiong Yang, Xiaofang Li, Ranhui Li

Immunology

DOI

2020

Expansion of Group 2 Innate Lymphoid Cells in Patients with End-Stage Renal Disease and Their Clinical Significance

Gao-Yu Liu, Xiaohui Deng, Xing Li, Yingjiao Cao, Yan‐Fang Xing, Pan Zhou, Aihua Lei, Quan Yang, Kai Deng, Hui Zhang, Jie Zhou

The Journal of Immunology

DOI

2020

Author response for "TFF3 mediates the NF-kappaB/COX2 pathway to regulate PMN-MDSCs activation and protect against necrotizing enterocolitis"

Jing-Ping Liu, Qiong Yang, Ziyang Chen, Shuaijun Lv, Jian Tang, Z. Xing, Mengyu Shi, Aihua Lei, Gang Xiao, Yumei He

DOI

2019

Cell-surface molecule-mediated cell–cell interactions in the regulation of ILC2-driven allergic inflammation

Aihua Lei, Jie Zhou

Cellular and Molecular Life Sciences

DOI

2019

Cyclooxygenase-1 Regulates the Development of Follicular Th Cells via Prostaglandin E2

Ting Liu, Qiong Yang, Ying-Jiao Cao, Wei-Ming Yuan, Aihua Lei, Pan Zhou, Wei Zhou, Yong-Dong Liu, M. Shi, Quan Yang, Jinyi Tang, Hai-Kun Wang, Hui Zhang, Ying Yu, Jie Zhou

Journal of Immunology

DOI

2019

IRF-7 Is a Critical Regulator of Type 2 Innate Lymphoid Cells in Allergic Airway Inflammation.

Juan He, Qiong Yang, Q. Xiao, Aihua Lei, Xing Li, Pan Zhou, Ting Liu, Lijuan Zhang, Kun Shi, Quan Yang, Jun-Chao Dong, Jie Zhou

Cell Reports

DOI

2019

Polymorphonuclear myeloid‐derived suppressor cells attenuate allergic airway inflammation by negatively regulating group 2 innate lymphoid cells

Ying-Jiao Cao, Yumei He, Xiangyang Wang, Yong-Dong Liu, Kun Shi, Zheng Zheng, Xue Su, Aihua Lei, Juan He, Jie Zhou

Immunology

DOI

2018

HLA-DR-/lowCD33+CD11b+CD15+CD14-多型核粒细胞在子宫内膜异位症中的作用

陈海文，李锦城，雷爱华

《热带医学杂志》

2018

ICAM-1 controls development and function of ILC2

Aihua Lei, Q. Xiao, Gaoyu Liu, Kun Shi, Qiong Yang, Xing Li, Yu-feng Liu, Hai-Kun Wang, W. Cai, Yu-juan Guan, D. Gabrilovich, Jie Zhou

Journal of Experimental Medicine

DOI

2017

Neutrophils and PMN-MDSCs: their biological role and interaction with stromal cells

Jie Zhou, Y. Nefedova, Aihua Lei, D. Gabrilovich

Seminars in Immunology

DOI

2017

Expansion of monocytic myeloid‐derived suppressor cells in endometriosis patients: A pilot study

Haiwen Chen, Shuang Qin, Aihua Lei, Xing Li, Qi Gao, Jing-Yin Dong, Qing Xiao, Jie Zhou

International Immunopharmacology

DOI

2017

Neutrophil count is associated with myeloid derived suppressor cell level and presents prognostic value for hepatocellular carcinoma patients

Xing Li, Yan-Fang Xing, Aihua Lei, Q. Xiao, Zhi-Mei Lin, Ying-Fen Hong, Xiang-Yuan Wu, Jie Zhou

OncoTarget

DOI

2016

Myeloid deprived suppressor cell to mediate the prognostic value of neutrophil for advanced hepatocellular carcinoma patients.

Xing Li, Aihua Lei, Yan-Fang Xing, Zhi-Mei Lin, Ying-Fen Hong, Q. Xiao, Min Dong, Q. Lin, Xiang-Yuan Wu, Jie Zhou

DOI

2016

Atorvastatin promotes the expansion of myeloid‐derived suppressor cells and attenuates murine colitis

Aihua Lei, Qiong Yang, Xing Li, Haiwen Chen, M. Shi, Q. Xiao, Ying-Jiao Cao, Yumei He, Jie Zhou

Immunology

DOI

2016

Hypoxemia is an independent predictor of bronchiolitis obliterans following respiratory adenoviral infection in children

Pei-Qiong Wu, Xing Li, Wen-Hui Jiang, Gen-Quan Yin, Aihua Lei, Q. Xiao, Jian-Jun Huang, Zhi-wei Xie, L. Deng

SpringerPlus

DOI

2016

Clinical Significance of Myeloid‐Derived Suppressor Cells in Human Immunodeficiency Virus‐1/ Hepatitis C Virus‐coinfected Patients

Aihua Lei, Qiong Yang, W. Cai, Yu-feng Liu, Y. Lan, Aiping Qin, F. Hu, Jie Zhou

Scandinavian Journal of Immunology

DOI

2014

髓系衍生的抑制性细胞与肿瘤免疫耐受关系的研究进展

雷爱华，周洁

《生物化学与生物物理进展》

精选作品

期刊论文

Itaconate as a Potent Regulator of Neutrophil Responses in Host Defence and Inflammation

Lipid nanoparticle-delivered mRNA vaccine encoding the MOMP of Chlamydia psittaci elicits protective immune responses in BALB/c mice

Correction: ICAM-1 controls development and function of ILC2

髓系抑制性细胞调节炎症性疾病中Th17应答的研究进展

新生儿期MDSCs免疫调节作用的研究进展

肺炎支原体黏附蛋白P30研究进展

Suppressing neutrophil itaconate production attenuates Mycoplasma pneumoniae pneumonia

The role of hormones in ILC2 ‐driven allergic airway inflammation

Total Flavonoids from Camellia oleifera Alleviated Mycoplasma pneumoniae-Induced Lung Injury via Inhibition of the TLR2-Mediated NF-κB and MAPK Pathways

Interferons as negative regulators of ILC2s in allergic lung inflammation and respiratory viral infections

Mycoplasma genitalium Protein of Adhesion Suppresses T Cell Activation via CypA-CaN-NFAT Pathway

Protective Immunity against Chlamydia psittaci Lung Infection Induced by a DNA Plasmid Vaccine Carrying CPSIT_p7 Gene Inhibits Dissemination in BALB/c Mice

Nitric Oxide-Producing Polymorphonuclear Neutrophils Confer Protection Against Chlamydia psittaci in Mouse Lung Infection

Lacticaseibacillus caseiCNRZ1874 supplementation promotes M1 alveolar macrophage activation and attenuatesMycoplasma pneumoniaepneumonia

Treg调控ILC2参与炎症性疾病的研究进展

靶向髓系抑制性细胞的药物在肿瘤治疗中的研究进展

Efficacy of Pgp3 vaccination for Chlamydia urogenital tract infection depends on its native conformation

DnaJ, a promising vaccine candidate against Ureaplasma urealyticum infection

The Beneficial Role of Probiotic Lactobacillus in Respiratory Diseases

Angiotensin II enhances group 2 innate lymphoid cell responses via AT1a during airway inflammation

短链脂肪酸在炎症性肠病中的免疫调节作用

Insights Into Host Cell Cytokines in Chlamydia Infection

TFF3 mediates the NF‐κB/COX2 pathway to regulate PMN‐MDSCs activation and protect against necrotizing enterocolitis

Biological functions of IL‐17‐producing cells in mycoplasma respiratory infection

Bilirubin represents a negative regulator of ILC2 in allergic airway inflammation

PPARγ enhances ILC2 function during allergic airway inflammation via transcription regulation of ST2

GrpE Immunization Protects Against Ureaplasma urealyticum Infection in BALB/C Mice

Role of myeloid cells in the regulation of group 2 innate lymphoid cell‐mediated allergic inflammation

Expansion of Group 2 Innate Lymphoid Cells in Patients with End-Stage Renal Disease and Their Clinical Significance

Author response for "TFF3 mediates the NF-kappaB/COX2 pathway to regulate PMN-MDSCs activation and protect against necrotizing enterocolitis"

Cell-surface molecule-mediated cell–cell interactions in the regulation of ILC2-driven allergic inflammation

Cyclooxygenase-1 Regulates the Development of Follicular Th Cells via Prostaglandin E2

IRF-7 Is a Critical Regulator of Type 2 Innate Lymphoid Cells in Allergic Airway Inflammation.

Polymorphonuclear myeloid‐derived suppressor cells attenuate allergic airway inflammation by negatively regulating group 2 innate lymphoid cells

HLA-DR-/lowCD33+CD11b+CD15+CD14-多型核粒细胞在子宫内膜异位症中的作用

ICAM-1 controls development and function of ILC2

Neutrophils and PMN-MDSCs: their biological role and interaction with stromal cells

Expansion of monocytic myeloid‐derived suppressor cells in endometriosis patients: A pilot study

Neutrophil count is associated with myeloid derived suppressor cell level and presents prognostic value for hepatocellular carcinoma patients

Myeloid deprived suppressor cell to mediate the prognostic value of neutrophil for advanced hepatocellular carcinoma patients.

Atorvastatin promotes the expansion of myeloid‐derived suppressor cells and attenuates murine colitis

Hypoxemia is an independent predictor of bronchiolitis obliterans following respiratory adenoviral infection in children

Clinical Significance of Myeloid‐Derived Suppressor Cells in Human Immunodeficiency Virus‐1/ Hepatitis C Virus‐coinfected Patients

髓系衍生的抑制性细胞与肿瘤免疫耐受关系的研究进展

研究方向