百晓学者学者目录

陈霁云

副教授、助理教授，厦门大学

精选作品

期刊论文

2026

Potential role of a CRISPR-Cas-activated toxin-antitoxin system in bacterial immunity

Jiyun Chen, Linglong Huang, Hong Chen, Xueyan Li, Xiaofeng Lin, Chenmin Guo, Xi Liu, Guowei Fu, Ying Chen, Liang Liu

Nature Communications

DOI

2026

A phage-encoded small RNA that mimics chimeric guide to inhibit CRISPR-Cas9

Ying Chen, Peng Zhao, Chenmin Guo, Dan-Dan Chen, Cai-Hong Yun, Jiyun Chen, Liang Liu

bioRxiv

DOI

2025

Cas9 Cis/Trans Cleavage Mechanisms: Cross-System CRISPR Insights and Diagnostic Applications

Xueying Li, Ying Chen, Linglong Huang, Jiyun Chen, Liang Liu

Health and Metabolism

DOI

2025

The discovery of Cas9's trans‐cleavage activity: Unlocking new molecular diagnostic tools

Ying Chen, Jiyun Chen, Liang Liu

Clinical and Translational Medicine

DOI

2025

Cas12h is a crRNA-guided DNA nickase that can be utilized for precise gene editing

Wenwen Xiang, Xiaofeng Lin, Yunqian Yang, Linglong Huang, Ying Chen, Jiyun Chen, Liang Liu

Cell Reports

DOI

2025

Functional Coupling and Evolutionary Relationships Between Toxin–Antitoxin Systems and CRISPR-Cas Systems

Yibo Meng, Jiyun Chen, Liang Liu

Toxins

DOI

2025

Structural basis of ssDNA-guided NADase activation of prokaryotic SPARTA system

Rong Hu, Chen-Ming Guo, Xiaotian Liu, Yuan Lin, Zixin Yang, Zhixin Li, Ye Yang, E. Ma, Yiyi Li, Jiyun Chen, Liang Liu

Nucleic Acids Research

DOI

2024

Trans-nuclease activity of Cas9 activated by DNA or RNA target binding

Jiyun Chen, Ying Chen, Linglong Huang, Xiaofeng Lin, Hong Chen, Wenwen Xiang, Liang Liu

Nature Biotechnology

DOI

2024

DNA target binding-induced pre-crRNA processing in type II and V CRISPR-Cas systems

Jiyun Chen, Xiao-Feng Lin, Wenwen Xiang, Ying Chen, Yueming Zhao, Linglong Huang, Liang Liu

Nucleic Acids Research

DOI

2023

Structural and mechanistic insight into ribosomal ITS 2 RNA processing 2 by nuclease-kinase machinery 3 4

Jiyun Chen, Hong Chen, Shanshan Li, Xiao-Feng Lin, Rong Hu, Kai-Ming Zhang, Liang Liu

2022

Structural basis for MTA1c-mediated DNA N6-adenine methylation

Jiyun Chen, Rong Hu, Ying Chen, Xiaofeng Lin, Wenwen Xiang, Hong Chen, Canglin Yao, Liang Liu

Nature Communications

DOI

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