百晓学者学者目录

陈兰芬

副教授、博士生导师、博导、教授，厦门大学

精选作品

期刊论文

2025

Welcoming new Developmental Cell advisors.

Hong Zhang, Hongmei Wang, Lanfen Chen, Qiang Gao, Yuling Jiao, Xue-Mei Chen, Jia-Wei Wang

Developmental Cell

DOI

2023

SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling

Dongxue Su, Yuxi Li, Weiji Zhang, Huan Gao, Yao Cheng, Yongqiang Hou, Jun-Hong Li, Yi Ye, Zhangjian Lai, Zhe Li, Hai-Tao Huang, Jia-Xi Li, Jin-Huan Li, Meng-Yu Cheng, Nian Cheng, N. Wu, Zhi'en Zhou, Yunzhi Xing, Yu Zhao, He-He Liu, Jiayu Tang, Qing-Hua Chen, Li-Xin Hong, WenGang Li, Zhi-Hai Peng, Bin Zhao, Randy L. Johnson, Pingguo Liu, Wan-Jin Hong, Lanfen Chen, Da-Wang Zhou

Journal of Clinical Investigation

DOI

2022

非经典Hippo信号通路调控免疫稳态

赵昊，史一然，章津嘉，陈兰芬

《厦门大学学报(自然科学版)》

2021

TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection

Jing Geng, Yi-Ran Shi, Jinjia Zhang, Bingying Yang, Ping Wang, Weihong Yuan, Hao Zhao, Jun-Hong Li, Funiu Qin, Li-Xin Hong, Chang-Chuan Xie, Xianming Deng, Yu-Jie Sun, Cong-Ying Wu, Lanfen Chen, Da-Wang Zhou

Nature Communications

DOI

2021

A new ALK inhibitor overcomes resistance to first‐ and second‐generation inhibitors in NSCLC

Yuechao Lu, Zhenzhen Fan, Su-Jie Zhu, Xiaoxing Huang, Zhong Zhuang, Yunzhan Li, Zhou Deng, Lei Gao, Xue-Hui Hong, Ting Zhang, Li Li, Xi-Huan Sun, Wei Huang, Jingfang Zhang, Yan Liu, Bao-Ding Zhang, Jie Jiang, Fu Gui, Zheng Wang, Qiyuan Li, Si-Yang Song, Xin Huang, Qia-Qing Wu, Lanfen Chen, Da-Wang Zhou, Jian-Ming Zhang, Cai-Hong Yun, Liang Chen, Xianming Deng

EMBO Molecular Medicine

DOI

2020

Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer.

Yue-Zhou Wang, Lei Zhang, Lei Zhang, Yanling Wei, Wei Huang, Li Li, An-An Wu, A. Dastur, P. Greninger, Walter Bray, Chen-Song Zhang, Mengqi Li, Wenhua Lian, Zhi-Yu Hu, Xiaoyong Wang, Gang Liu, Lu-Ming Yao, J. Guh, Lanfen Chen, Hong-Rui Wang, Da-Wang Zhou, Sheng-Cai Lin, Qing-Yan Xu, Yue-Mao Shen, Jian-Ming Zhang, M. Jurica, C. Benes, Xianming Deng

Cell Chemical Biology

DOI

2020

A trustworthy CpG nanoplatform for highly safe and efficient cancer photothermal combined immunotherapy.

Ming Jiang, Jinjia Zhang, Yi-Ran Shi, W. Yang, Jingchao Li, Duo Sun, Sijin Xiang, Xiao-Lan Chen, Lanfen Chen, Nan-Feng Zheng

Nanoscale

DOI

2020

Editorial: Hippo Signaling in the Immune System

Lanfen Chen, Hong-Bo Chi, T. Kinashi

Frontiers in Immunology

DOI

2020

Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy

Lintao Song, Zhi-Hua Liu, Hui Hu, Ying Yang, T. Y. Li, Zhizhong Lin, Jing Ye, Jia-Ning Chen, Xi Huang, Dong-Tai Liu, Jing Zhou, Yi-Ran Shi, Hao Zhao, Chang-Chuan Xie, Lanfen Chen, E. Song, Shu-Yong Lin, Sheng-Cai Lin

Nature Communications

DOI

2019

Hippo信号通路调控免疫细胞稳态维持的研究进展

李俊宏，令狐月月，陈兰芬

《中国免疫学杂志》

2019

免疫细胞代谢及其功能调节研究进展

耿晶，李佳薪，念诚，杨冰莹，周大旺，陈兰芬

《中国细胞生物学学报》

2019

FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis.

Suyuan Ji, Qingxu Liu, Shihao Zhang, Qing-Hua Chen, Cong Wang, Weiji Zhang, Chen Xiao, Yuxi Li, Nian Cheng, Jiaxin Li, Jun-Hong Li, Jing Geng, Li-Xin Hong, Chang-Chuan Xie, Ying He, Xing Chen, Xun Li, Zhen-Yu Yin, H. You, K. Lin, Qiao Wu, Chundong Yu, Randy L. Johnson, Li Wang, Lanfen Chen, Fen Wang, Da-Wang Zhou

Developmental Cell

DOI

2019

Non-canonical Hippo signaling regulates immune responses.

Lanfen Chen

Advances in Immunology

DOI

2019

The Hippo Signaling Pathway in Regenerative Medicine.

Li-Xin Hong, Yuxi Li, Qingxu Liu, Qing-Hua Chen, Lanfen Chen, Da-Wang Zhou

Methods in molecular biology

DOI

2019

Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis

Ping Wang, Jing Geng, Jia-Hui Gao, Hao Zhao, Jun-Hong Li, Yi-Ran Shi, Bingying Yang, Chen Xiao, Yue-Yue Linghu, Xiu-Feng Sun, Xin Chen, Li-Xin Hong, Funiu Qin, Xun Li, Jau-Song Yu, H. You, Zeng-Qiang Yuan, Da-Wang Zhou, Randy L. Johnson, Lanfen Chen

Nature Communications

DOI

2018

Hippo信号通路通过调控Skp2活性从而抑制细胞多倍体产生及肝癌发生

张世浩，陈青花，刘清许，Yuxi Li，Xiufeng Sun，Lixin Hong，Suyuan Ji，Chengyan Liu，Jing Geng，Weiji Zhang，Zhonglei Lu，Zhen-Yu Yin，Yuanyuan Zeng，Kwang-Huei Lin，Qiao Wu，Qiyuan Li，Keiko Nakayama，Keiich I.Nakayama，Xianming Deng，Randy L.Johnson，Liang Zhu，Daming Gao，陈兰芬，周大旺

《科学新闻》

2018

控制肝脏组织发育、再生重塑与大小的关键蛋白质机器

陈兰芬，邓贤明，陈正军，程新，黄晶，姜海，周兆才，丁劲，卫立辛，陈军，赵斌，周大旺

《中国基础科学》

2018

Publisher Correction: The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells

Jing Geng, Shu-Juan Yu, Hao Zhao, Xiu-Feng Sun, Xun Li, Ping Wang, Xiao-Lin Xiong, Li-Xin Hong, Chang-Chuan Xie, Jia-Hui Gao, Yi-Ran Shi, Jia-Qi Peng, Randy L. Johnson, Neng-Ming Xiao, Lin-Rong Lu, Jia-Huai Han, Da-Wang Zhou, Lanfen Chen

Nature Immunology

DOI

2018

Role of Hippo signaling in regulating immunity

Li-Xin Hong, Xun Li, Da-Wang Zhou, Jing Geng, Lanfen Chen

Cellular & Molecular Immunology

DOI

2017

Hippo信号通路相关分子参与免疫细胞功能调控的研究进展

耿晶，洪丽欣，陈兰芬

《生命科学》

2017

Hippo信号通路调控免疫细胞的功能

余淑娟，耿晶，陈兰芬

《遗传》

2017

Targeting BRK-Positive Breast Cancers with Small-Molecule Kinase Inhibitors.

Jie Jiang, Fu Gui, Zhixiang He, Li Li, Yunzhan Li, Shun-Ying Li, Xinrui Wu, Zhou Deng, Xi-Huan Sun, Xiaoxing Huang, Wei Huang, Shang-Yu Han, Ting Zhang, Zheng Wang, B. Jiao, Si-Yang Song, Hong-Rui Wang, Lanfen Chen, Da-Wang Zhou, Qiang Liu, R. Ren, Jian-Ming Zhang, Xianming Deng

Cancer Research

DOI

2017

Hippo signaling suppresses cell ploidy and tumorigenesis through Skp2

Shihao Zhang, Qing-Hua Chen, Qingxu Liu, Yuxi Li, Xiu-Feng Sun, Li-Xin Hong, Suyuan Ji, Cheng-Yan Liu, Jing Geng, Weiji Zhang, Zhonglei Lu, Zhen-Yu Yin, Yuan-Yuan Zeng, K. Lin, Qiao Wu, Qiyuan Li, Keiko Nakayama, K. Nakayama, Xianming Deng, Randy L. Johnson, Liang Zhu, Da-Ming Gao, Lanfen Chen, Da-Wang Zhou

Cancer Cell

DOI

2017

The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells

Jing Geng, Shu-Juan Yu, Hao Zhao, Xiu-Feng Sun, Xun Li, Ping Wang, Xiao-Lin Xiong, Li-Xin Hong, Chang-Chuan Xie, Jia-Hui Gao, Yi-Ran Shi, Jia-Qi Peng, Randy L. Johnson, Neng-Ming Xiao, Lin-Rong Lu, Jia-Huai Han, Da-Wang Zhou, Lanfen Chen

Nature Immunology

DOI

2017

The functions of the Hippo signaling pathway in immune cells.

Shu-Juan Yu, Jing Geng, Lanfen Chen

Yi chuan = Hereditas

DOI

2016

Hippo信号通路调控宿主抗感染的重要防御机制

耿晶，孙秀峰，王平，王晓珍，张世浩，赵昊，熊晓琳，陈兰芬，周大旺

《中国科学基金》

2016

Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration

F. Fan, Zhixiang He, L. Kong, Qing-Hua Chen, Q. Yuan, Shihao Zhang, Jiye Ye, Hao Liu, Xiu-Feng Sun, Jing Geng, Lun-Zhi Yuan, Li-Xin Hong, Chen Xiao, Weiji Zhang, Xi-Huan Sun, Yunzhan Li, Ping Wang, Lihong Huang, Xinrui Wu, Zhiliang Ji, Qiao Wu, N. Xia, N. Gray, Lanfen Chen, Caihong Yun, Xianming Deng, Da-Wang Zhou

Science Translational Medicine

DOI

2015

The kinases Mst1 and Mst2 positively regulate phagocyte ROS induction and bactericidal activity

Jing Geng, Xiu-Feng Sun, Ping Wang, Shihao Zhang, Xiao-Zhen Wang, Hongtan Wu, Li-Xin Hong, Chang-Chuan Xie, Xun Li, Hao Zhao, Qingxu Liu, Ming-Ting Jiang, Qing-Hua Chen, Jinjia Zhang, Yang Li, Si-Yang Song, Hong-Rui Wang, R. Zhou, Randy L. Johnson, Kun-Yi Chien, Sheng-Cai Lin, Jia-Huai Han, J. Avruch, Lanfen Chen, Da-Wang Zhou

Nature Immunology

DOI

2015

The Hippo signaling pathway in liver regeneration and tumorigenesis.

Li-Xin Hong, Yabo Cai, Ming-Ting Jiang, Da-Wang Zhou, Lanfen Chen

Acta Biochimica et Biophysica Sinica

DOI

2015

Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis

Hongtan Wu, Lu-Yao Wei, F. Fan, Suyuan Ji, Shihao Zhang, Jing Geng, Li-Xin Hong, Xin Fan, Qing-Hua Chen, Jing Tian, Ming-Ting Jiang, Xiu-Feng Sun, Changnan Jin, Zhen-Yu Yin, Qingxu Liu, Jinjia Zhang, Funiu Qin, K. Lin, Jau-Song Yu, Xianming Deng, Hong-Rui Wang, Bin Zhao, Randy L. Johnson, Lanfen Chen, Da-Wang Zhou

Nature Communications

DOI

2013

Mst1 and Mst2 kinases: regulations and diseases

Funiu Qin, Jing Tian, Da-Wang Zhou, Lanfen Chen

Cell & Bioscience

DOI

2013

CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling

S. Hosomi, Zhangguo Chen, K. Baker, Lanfen Chen, Yu‐Hwa Huang, T. Olszak, S. Zeissig, Jing H. Wang, O. Mandelboim, N. Beauchemin, L. L. Lanier, Richard S. Blumberg

European Journal of Immunology

DOI

2013

Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis

Jian-Feng Wu, Zhe Huang, Junming Ren, Zhirong Zhang, Peng He, Yang-Xin Li, Jian-Hui Ma, Wanze Chen, Yingying Zhang, Xiaojuan Zhou, Zhen-Tao Yang, Su-qin Wu, Lanfen Chen, Jia-Huai Han

Cell Research

DOI

2013

The Ets transcription factor GABP is a novel component of the Hippo pathway essential for growth and antioxidant defense

Hongtan Wu, Yubo Xiao, Shihao Zhang, Suyuan Ji, Lu-Yao Wei, F. Fan, Jing Geng, Jing Tian, Xiu-Feng Sun, Funiu Qin, Changnan Jin, Jianjun Lin, Zhen-Yu Yin, Ting Zhang, Lian-Zhong Luo, Yang Li, Si-Yang Song, Sheng-Cai Lin, Xianming Deng, F. Camargo, J. Avruch, Lanfen Chen, Da-Wang Zhou

Cell Reports

DOI

2012

Hippo pathway in intestinal homeostasis and tumorigenesis

Lanfen Chen, Funiu Qin, Xian-Ming Deng, J. Avruch, Da-Wang Zhou

Protein & Cell

DOI

2012

The Short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction

Lanfen Chen, Zhangguo Chen, K. Baker, Elizabeth M. Halvorsen, A. D. da Cunha, Magdalena B. Flak, G. Gerber, Yu‐Hwa Huang, S. Hosomi, J. Arthur, Kenneth J. Dery, Takashi Nagaishi, N. Beauchemin, K. Holmes, J. Ho, J. Shively, C. Jobin, A. Onderdonk, L. Bry, H. Weiner, Darren E. Higgins, R. Blumberg

Immunity

DOI

2011

CEACAM1 dampens antitumor immunity by down-regulating NKG2D ligand expression on tumor cells

Zhangguo Chen, Lanfen Chen, K. Baker, T. Olszak, S. Zeissig, Yu‐Hwa Huang, Timothy T. Kuo, O. Mandelboim, N. Beauchemin, L. Lanier, R. Blumberg

Journal of Experimental Medicine

DOI

2009

Editorial: CEACAM1: fine‐tuned for fine‐tuning

Zhangguo Chen, Lanfen Chen, Richard S. Blumberg

Journal of Leukocyte Biology

DOI

2008

Su.97. Inhibitory Regulation of CEACAM1 on T Cell Receptor and NKG2D Mediated Signaling

Zhangguo Chen, Lanfen Chen, Shuo-Wang Qiao, Takashi Nagaishi, R. Blumberg

DOI

2008

CEACAM1 and the regulation of mucosal inflammation

Takashi Nagaishi, Zhi-Bin Chen, Lanfen Chen, H. Iijima, A. Nakajima, R. Blumberg

Mucosal Immunology

DOI

2008

The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naïve T cells

Da-Wang Zhou, B. Medoff, Lanfen Chen, Le-Qun Li, Xian-Feng Zhang, M. Praskova, Matthew Liu, Aimee L Landry, R. Blumberg, V. Boussiotis, R. Xavier, J. Avruch

Proceedings of the National Academy of Sciences of the United States of America

DOI

2008

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Inhibits Proximal TCR Signaling by Targeting ZAP-70

Nagaishi, Richard S. Blumberg, Zhang-Guo Chen, Lanfen Chen, Shuo-Wang Qiao, Takashi

2006

This information is current as Lymphocytes Evidence for Loss of Apoptotic Activity in Mice : − / − R 7 Encephalomyelitis in P 2 X Exacerbation of Experimental Autoimmune

Lanfen Chen, C. Brosnan

2006

Regulation of immune response by P2X7 receptor.

Lanfen Chen, C. Brosnan

Critical Reviews in Immunology

DOI

2006

Experimental autoimmune encephalomyelitis disrupts endocannabinoid-mediated neuroprotection.

Anke Witting, Lanfen Chen, E. Cudaback, A. Straiker, L. Walter, B. Rickman, T. Möller, C. Brosnan, N. Stella

Proceedings of the National Academy of Sciences of the United States of America

DOI

2005

Transcriptional Profiling of γδ T Cells Identifies a Role for Vitamin D in the Immunoregulation of the Vγ9Vδ2 Response to Phosphate-Containing Ligands1

Lanfen Chen, M. T. Cencioni, D. Angelini, G. Borsellino, L. Battistini, C. Brosnan

Journal of Immunology

DOI

2004

Interleukin-1β Induces a Reactive Astroglial Phenotype via Deactivation of the Rho GTPase–Rock Axis

G. John, Lanfen Chen, Mark A. Rivieccio, C. Melendez-Vasquez, Adam Hartley, C. Brosnan

Journal of Neuroscience

DOI

2003

Upregulation of Group 1 CD1 Antigen Presenting Molecules in Guinea Pigs with Experimental Autoimmune Encephalomyelitis: An Immunohistochemical Study

B. Cipriani, Lanfen Chen, K. Hiromatsu, H. Knowles, C. S. Raine, L. Battistini, S. Porcelli, C. Brosnan

Brain Pathology

DOI

2002

Involvement of Classical and Novel Protein Kinase C Isoforms in the Response of Human Vγ9Vδ2 T Cells to Phosphate Antigens1

B. Cipriani, H. Knowles, Lanfen Chen, L. Battistini, C. Brosnan

Journal of Immunology

DOI

研究方向

有

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