陈守文｜湖北大学｜学者主页

2026

谷氨酸脱羧酶pH适应性改造及全细胞催化合成γ-氨基丁酸

朱江，赵毅雯，田冠，刘双月，徐文祚，余焱，蔡冬波，王世依，陈守文

《微生物学通报》

2026

枯草芽胞杆菌漆酶的异源表达及催化腰果酚氧化聚合的研究

张丹，王世依，蔡冬波，陈守文，马昕

《湖北大学学报(自然科学版)》

2026

Combining expression optimization and protein engineering for high-level production of protein-glutaminase in Bacillus licheniformis

Asfandyar, Rui-Bin Zhang, Shuai Zhao, A. Ishaq, Penghui He, Y. Rao, D. Cai, Shou-Wen Chen

Food Bioscience

DOI

2026

Engineering a non-oxidative glycolysis pathway in industrial Bacillus licheniformis for carbon-efficient production of acetyl-CoA derived biochemicals

Jiang Zhu, Jianling Kang, Min Liu, You-You Li, Yuhan Wu, Y. Zhan, Penghui He, Yongqing Liao, Junhui Li, Shiyi Wang, D. Cai, Shou-Wen Chen

Chemical Engineering Journal

DOI

2026

System reconstruction of Bacillus licheniformis for efficient expression of alkaline protease

Qing Zhang, Mengyuan Zhang, Zhi-Hao Zhu, Hai-Jin Ma, Fei Mo, Jiaqi Lei, Shisi He, Yongqing Liao, Shihao Yan, D. Cai, Shou-Wen Chen

Synthetic and Systems Biotechnology

DOI

2026

Development of a bifunctional dynamic control system for effective product synthesis in Bacillus licheniformis DW2

Yi Rao, Jiaqi Wang, J F Liu, Rui Zhao, Xin Ma, Dongbo Cai, Shouwen Chen

Bioresource Technology

DOI

2026

Multidimensional Metabolic Engineering for Green and Sustainable Bioproduction of Serotonin from Glucose in Bacillus licheniformis

Xinyuan Yang, Yue Wang, Ji Li, Wenyuan Liu, Yongqing Liao, Ruixue Zhu, Yangyang Zhan, Xin Ma, Yi Rao, Dongbo Cai, Shouwen Chen

Journal of Agricultural and Food Chemistry

DOI

2026

Protein engineering combined with combinatorial optimization of critical synthetase cluster for efficient production of 1-Deoxynojirimycin in B. amyloliquefaciens

Xujie Li, Xin Feng, Aoying Dong, Shihao Yan, Chenshuo Zhang, Yi Rao, Zheng Zhang, Hui Tian, Dongbo Cai, Shouwen Chen

Bioresource Technology

DOI

2025

基于分子改造和宿主优化促地衣芽胞杆菌高效表达γ-谷氨酰转肽酶

雷家琪，张清，祝志豪，廖永庆，陈守文，蔡冬波

《生物工程学报》

DOI

2025

Heterologous expression of keratinase SapB in Bacillus licheniformis enables efficient transformation of feather waste.

A. Ishaq, Asfandyar, Zheng Zhang, Qin Wang, Penghui He, Yong-Jie Zhang, Xujie Li, D. Cai, Min Xiong, Shou-Wen Chen

International Journal of Biological Macromolecules

DOI

2025

Overexpressing Endopeptidase Inhibitor IseA Enhances Biomass and Biochemical Production of Bacillus licheniformis

Yong-Jie Zhang, Penghui He, Shiying Hu, Rui-Bin Zhang, Asfandyar, Shou-Wen Chen

Current Microbiology

DOI

2025

Unraveling the chrono-regulatory function of PhoP in nitrogen metabolism: A multi-scale engineering framework aimed at optimizing the synthesis of poly-γ-glutamic acid in Bacillus licheniformis

Qing Zhang, Shisi He, Zhi-Hao Zhu, Fangzhou Cheng, Ya-ping Jin, Wanying Zhu, Fan Yang, Yaozhong Chen, Mengyuan Zhang, Xin Li, D. Cai, Shou-Wen Chen

Chemical Engineering Journal

DOI

2025

Cell membrane engineering of Bacillus licheniformis for the enhancement of heterologous protein production.

Asfandyar, Y. Rao, A. Ishaq, Yong-Jie Zhang, Rui-Bin Zhang, D. Cai, Penghui He, Shou-Wen Chen

International Journal of Biological Macromolecules

DOI

2025

Efficient sustainable production of protocatechuic acid from glucose by engineered Bacillus licheniformis

Y. Rao, Jiaqi Wang, Rui Zhao, Y. Zhan, Xin Ma, Penghui He, D. Cai, Shou-Wen Chen

Chemical Engineering Journal

DOI

2025

Protein engineering, expression optimization, and application of alkaline protease from Alkalihalobacillus clausii FYX.

Yuxi Fu, Y. Rao, Yongqing Liao, Qing Zhang, Xin Ma, D. Cai, Shou-Wen Chen

International Journal of Biological Macromolecules

DOI

2025

Elucidating metabolic mechanisms underlying the influence of specific growth rate on alkaline protease synthesis in Bacillus licheniformis through combined omics and computational modeling analysis

Ying Zhang, Zhihao Liu, Jingmin Hu, Qiaoer Yao, Hongfei Xu, Qing Zhang, Shouwen Chen, Y.Y. Wang

Bioresource Technology

DOI

2025

Optimizing genome editing efficiency in Streptomyces fradiae via a CRISPR/Cas9n-mediated editing system

Yanmin Wu, Hui Jin, Qiang Yu, Zihan Wei, Jiang Zhu, Xiangqi Qiu, Gan Luo, Junhui Li, Yangyang Zhan, Dongbo Cai, Shouwen Chen

Applied and Environmental Microbiology

DOI

2025

Metabolic engineering of Bacillus licheniformis DW2 for ectoine production

Xujie Li, Aoying Dong, Junru Yang, Jiang Zhu, Yangyang Zhan, Xin Ma, Dongbo Cai, Shouwen Chen

World Journal of Microbiology and Biotechnology

DOI

2024

饼粕肥对芽胞杆菌在烟草根际定殖及促生作用的影响

熊敏，苗朝棋，余涓萍，王冬，马昕，谭本奎，陈振国，陈守文

《中国烟草科学》

DOI

2024

微生物法合成γ-氨基丁酸的研究进展

王世依，赵毅雯，贾田丽，陈守文

《华中农业大学学报》

2024

Understanding energy fluctuation during the transition state: The role of AbrB in Bacillus licheniformis

Qing Zhang, Wanying Zhu, Shisi He, Jia Lei, Liang-Sheng Xu, Shiying Hu, Zheng Zhang, D. Cai, Shou-Wen Chen

Microbial Cell Factories

DOI

2024

A new ROS response factor YvmB protects Bacillus licheniformis against oxidative stress under adverse environment

Penghui He, Shiying Hu, Yong-Jie Zhang, Zhengwei Xiang, Zheng Zhang, Dong Wang, Shou-Wen Chen

Applied and Environmental Microbiology

DOI

2024

Transcription factor AbrB regulates ROS generation and clearance in Bacillus licheniformis.

Penghui He, Shiying Hu, Yong-Jie Zhang, Zhengwei Xiang, Anting Zhu, Shou-Wen Chen

Microbiology Research

DOI

2024

Developing a Bacillus licheniformis platform for de novo production of γ-aminobutyric acid and other glutamate-derived chemicals.

Shiyi Wang, Jiang Zhu, Yiwen Zhao, Shufeng Mao, Yi-Hui He, Fei-Xiang Wang, Tianli Jia, D. Cai, Junyong Chen, Dong Wang, Shouwen Chen

Metabolic Engineering

DOI

2024

Engineering Bacillus licheniformis as industrial chassis for efficient bioproduction from starch.

Jiang Zhu, Min Liu, Jianling Kang, Shiyi Wang, Ziyan Zha, Y. Zhan, Zhi Wang, Junhui Li, D. Cai, Shouwen Chen

Bioresource Technology

DOI

2024

Synthesis of Super-High-Viscosity Poly-γ-Glutamic Acid by pgdS-Deficient Strain of Bacillus licheniformis and Its Application in Microalgae Harvesting

Xiaohui Zhang, Wei Wu, Hongxiao Mou, Jun Liu, Lei Lei, Xin Li, Dongbo Cai, Yangyang Zhan, Xin Ma, Shouwen Chen

Microorganisms

DOI

2024

Modular metabolic engineering of Bacillus amyloliquefaciens for high-level production of green biosurfactant iturin A

Menglin She, Huijuan Zhou, Wanrong Dong, Yuxiang Xu, Lin Gao, Jiaming Gao, Yong Yang, Zhifan Yang, Dongbo Cai, Shouwen Chen

Applied Microbiology and Biotechnology

DOI

2024

High-level production of chitinase by multi-strategy combination optimization in Bacillus licheniformis

Zhimin Qi, Bo Lei, Min Xiong, Weijia Li, Yongqing Liao, Dongbo Cai, Xin Ma, Ruibin Zhang, Shouwen Chen

World Journal of Microbiology and Biotechnology

DOI

2024

Engineering the Tat-secretion pathway of Bacillus licheniformis for the secretion of cytoplasmic enzyme arginase

Yi Ji, Junliang Li, Yonglin Liang, Liang Li, Yajun Wang, Li Pi, Panpan Xing, Christopher T. Nomura, Shouwen Chen, Chengjun Zhu, Qin Wang

Applied Microbiology and Biotechnology

DOI

2024

A Convenient and Highly Efficient Strategy for Esterification of Poly (γ-Glutamic Acid) with Alkyl Halides at Room Temperature

Youhong Ai, Yangyang Zhan, Dongbo Cai, Shouwen Chen

Polymers

DOI

2024

Paradigm of engineering recalcitrant non-model microorganism with dominant metabolic pathway as a biorefinery chassis

Xiongying Yan, Weiwei Bao, Yalun Wu, Chenyue Zhang, Zhitao Mao, Qianqian Yuan, Zhousheng Hu, Penghui He, Qiqun Peng, Mimi Hu, Binan Geng, Hongwu Ma, Shouwen Chen, Qiang Fei, Qiaoning He, Shihui Yang

Nature Communications

DOI

2023

D,L-肽链内切酶基因cwlO缺失促进地衣芽孢杆菌利用L-谷氨酰胺合成聚γ-谷氨酸

王思，李鑫，彭芳，刘军，占杨杨，陈守文

《微生物学通报》

2023

解淀粉芽胞杆菌HZ-12中ysnE参与吲哚-3-乙酸合成的代谢途径研究

周慧娟，佘梦林，李孜燕，高林，高加明，蔡冬波，杨之帆，陈守文，马昕

《微生物学报》

2023

基于表达元件和宿主优化促地衣芽胞杆菌高效表达L-天冬酰胺酶

杨新愿，饶忆，张梦茜，王佳琪，刘文渊，蔡冬波，陈守文

《生物工程学报》

2023

Recent advances in keratinase production via protein engineering, breeding, and fermentation

A. Ishaq, Zheng Zhang, Penghui He, Min Xiong, Shou-Wen Chen

Advanced Agrochem

DOI

2023

High Production of Nattokinase via Fed-Batch Fermentation of the γ-PGA-Deficient Strain of Bacillus licheniformis

Xin Li, Jing Yang, Jun Liu, Xiaohui Zhang, Wei Wu, Dazhong Yan, Lihong Miao, Dongbo Cai, Xin Ma, Shouwen Chen

Fermentation

DOI

2023

Development of an Inosine Hyperproducer from Bacillus licheniformis by Systems Metabolic Engineering

Menglin Zhou, Yi Li, Youhua Cai, Yaqi Sun, Wu Chen, Jin Wang, Feng Shen, Yangyang Zhan, Binwu Ying, Shouwen Chen

Journal of Agricultural and Food Chemistry

DOI

2023

A novel toolbox for precise regulation of gene expression and metabolic engineering in Bacillus licheniformis

Yi Rao, Jiaqi Wang, Xinyuan Yang, Xinxin Xie, Yangyang Zhan, Xin Ma, Dongbo Cai, Shouwen Chen

Metabolic Engineering

DOI

2023

Construct a synthetic Entner–Doudoroff pathway in Bacillus licheniformis for enhancing lichenysin production

Shiying Hu, Chen Zhao, Yongjia Zhang, Xiaoting Wang, Penghui He, Shouwen Chen

World Journal of Microbiology and Biotechnology

DOI

2023

Enhancement of alkaline protease production in recombinant Bacillus licheniformis by response surface methodology

Ying Zhang, Jingmin Hu, Qing Hua Zhang, Dongbo Cai, Shouwen Chen, Yonghong Wang

Bioresources and Bioprocessing

DOI

2023

Metabolic Engineering of Bacillus licheniformis for the Bioproduction of Nicotinamide Riboside from Nicotinamide and Glucose

Menglin Zhou, Yi Li, Haotian Che, Yaqi Sun, Shan Wang, Yangyang Zhan, Dongbo Cai, Shouwen Chen

ACS Sustainable Chemistry & Engineering

DOI

2023

[Efficient production of L-asparaginase in Bacillus licheniformis by optimizing expression elements and host].

Xinyuan Yang, Yi Rao, Mengxi Zhang, Jiaqi Wang, Wenyuan Liu, Dongbo Cai, Shouwen Chen

PubMed

DOI

2023

Promoting cell growth for bio-chemicals production via boosting the synthesis of L/D-alanine and D-alanyl-D-alanine in Bacillus licheniformis

Zheng Zhang, Penghui He, Shiying Hu, Yanqing Yu, Xiaoting Wang, Ali Raza Ishaq, Shouwen Chen

World Journal of Microbiology and Biotechnology

DOI

2023

Systematic Adaptation of Bacillus licheniformis to 2-Phenylethanol Stress

Yangyang Zhan, Haixia Xu, Hween Tong Tan, Ying Swan Ho, Dongxiao Yang, Shuwen Chen, Shuwen Chen, Dave Siak‐Wei Ow, Xin Lv, Fang Wei, Xuezhi Bi, Shouwen Chen, Shouwen Chen

Applied and Environmental Microbiology

DOI

2023

Enhancing the activity of disulfide-bond-containing proteins via promoting disulfide bond formation in Bacillus licheniformis

Shi‐Yi Wang, Yiwen Zhao, Shufen Mao, Jiang Zhu, Yangyang Zhan, Dongbo Cai, Xin Ma, Dong Wang, Shouwen Chen

International Journal of Biological Macromolecules

DOI

2023

Systematic metabolic engineering of Bacillus licheniformis for hyperproduction of the antioxidant hydroxytyrosol

Yangyang Zhan, Fei Zhou, Wenqi Ruan, Hao Yin, Zhi Li, Huan Wang, Li Tao, Dongbo Cai, Shihui Yang, Xin Ma, Shouwen Chen

Green Chemistry

DOI

2023

Metabolic engineering of Bacillus amyloliquefaciens for efficient production of α-glucosidase inhibitor1-deoxynojirimycin

Xujie Li, Meng Zhang, Yu Lu, Ningyang Wu, Jiangang Chen, Jiangang Chen, Zhixia Ji, Yangyang Zhan, Xin Ma, Junyong Chen, Junyong Chen, Dongbo Cai, Shouwen Chen

Synthetic and Systems Biotechnology

DOI

2023

Microbial synthesis of bacitracin: Recent progress, challenges, and prospects

Jiang Zhu, Shi‐Yi Wang, Cheng Wang, Zhi Wang, Gan Luo, Junhui Li, Yangyang Zhan, Dongbo Cai, Shouwen Chen

Synthetic and Systems Biotechnology

DOI

2023

Assembled denitrifying consortia for efficient nitrate removal under low-COD/N conditions

Meng Jiang, Yating Wu, Penghui He, Shiyin Hu, Qingxi Li, Shouwen Chen

Chemical Engineering Journal

DOI

2023

A cell-free artificial anabolic pathway for direct conversion of CO 2 to ethanol

Wanrong Dong, Xiuling Ji, Yuhong Huang, Yaju Xue, Boxia Guo, Dongbo Cai, Shouwen Chen, Suojiang Zhang

Green Chemistry

DOI

2022

DegU负调控地衣芽胞杆菌普切明酸的合成及分泌

王冬，王攀，何轶慧，陈守文

《微生物学报》

2022

烟草青枯病抑病型土壤中有益微生物的组成分析

黎妍妍，李春黎，杨小琼，陈守文，李锡宏，杨勇

《烟草科技》

2022

Modular Engineering to Enhance Keratinase Production for Biotransformation of Discarded Feathers

Yongqing Liao, Min Xiong, Zhaoqi Miao, Ali Raza Ishaq, Min Zhang, Bichan Li, Yangyang Zhan, Dongbo Cai, Zhifan Yang, Jun Chen, Shouwen Chen

Applied Biochemistry and Biotechnology

DOI

2022

Sustainable production of 2-phenylethanol from agro-industrial wastes by metabolically engineered Bacillus licheniformis

Haixai Xu, Zhi Li, Leyi Li, Xiaomei Xie, Dongbo Cai, Zhi Wang, Yangyang Zhan, Shouwen Chen

LWT

DOI

2022

Engineered multiple translation initiation sites: a novel tool to enhance protein production in Bacillus licheniformis and other industrially relevant bacteria

Manyu Zhang, Jing Song, Jun Xiao, Jingjie Jin, Christopher T. Nomura, Shouwen Chen, Qin Wang

Nucleic Acids Research

DOI

2022

Transcription factor DegU-mediated multi-pathway regulation on lichenysin biosynthesis in Bacillus licheniformis

Shiying Hu, Penghui He, Yongjia Zhang, Meng Jiang, Qin Wang, Shihui Yang, Shouwen Chen

Metabolic Engineering

DOI

2022

Minimization and optimization of α-amylase terminator for heterologous protein production in Bacillus licheniformis

Yi Rao, Jingyao Yang, Jiaqi Wang, Xinyuan Yang, Mengxi Zhang, Yangyang Zhan, Xin Ma, Dongbo Cai, Zhangqian Wang, Shouwen Chen

Bioresources and Bioprocessing

DOI

2022

Enhanced production of iturin A by strengthening fatty acid synthesis modules in Bacillus amyloliquefaciens

Lin Gao, Menglin She, Jiao Shi, Dongbo Cai, Dong Wang, Min Xiong, Guoming Shen, Jiaming Gao, Min Zhang, Zhifan Yang, Shouwen Chen

Frontiers in Bioengineering and Biotechnology

DOI

2022

Enhanced production of poly-γ-glutamic acid via optimizing the expression cassette of Vitreoscilla hemoglobin in Bacillus licheniformis

Qing Zhang, Yaozhong Chen, Lin Gao, Jiangang Chen, Xin Ma, Dongbo Cai, Dong Wang, Shouwen Chen

Synthetic and Systems Biotechnology

DOI

2022

Enhanced aerobic denitrification performance with Bacillus licheniformis via secreting lipopeptide biosurfactant lichenysin

Meng Jiang, Qingxi Li, Shiyin Hu, Penghui He, Yinguagn Chen, Dongbo Cai, Yating Wu, Shouwen Chen

Chemical Engineering Journal

DOI

2022

Multilevel metabolic engineering of Bacillus licheniformis for de novo biosynthesis of 2-phenylethanol

Yangyang Zhan, Jiao Shi, Yuan Xiao, Fei Zhou, Huan Wang, Haixia Xu, Zhi Li, Shihui Yang, Dongbo Cai, Shouwen Chen

Metabolic Engineering

DOI

2022

Mitigation of tobacco bacteria wilt with microbial degradation of phenolic allelochemicals

Xiaohan Chang, Yi Wang, Jingguo Sun, Haibo Xiang, Yong Yang, Shouwen Chen, Jun Myoung Yu, Chunlei Yang

Scientific Reports

DOI

2022

Genetic and metabolic engineering for poly-γ-glutamic acid production: current progress, challenges, and prospects

Zheng Zhang, Penghui He, Dongbo Cai, Shouwen Chen

World Journal of Microbiology and Biotechnology

DOI

2022

Metabolic engineering of Zymomonas mobilis for continuous co-production of bioethanol and poly-3-hydroxybutyrate (PHB)

Yang Li, Ying Wang, Ruxiang Wang, Xiongying Yan, Jiewen Wang, Xia Wang, Shouwen Chen, Feng‐Wu Bai, Qiaoning He, Shihui Yang

Green Chemistry

DOI

2021

合成生物学时代基于非模式细菌的工业底盘细胞研究现状与展望

杨永富，耿碧男，宋皓月，胡蜜蜜，何桥宁，陈守文，白凤武，杨世辉

《生物工程学报》

DOI

2021

土壤高效解钾菌的筛选鉴定及烟草栽培应用效果评价

高加明，张健行，佘梦林，王冬，陈守文，马昕

《湖北农业科学》

DOI

2021

重组地衣芽胞杆菌全细胞催化合成淫羊藿次苷D2

肖源，张同，杨之帆，陈守文，占杨扬，陈俊

《武汉科技大学学报》

2021

微生物产角蛋白酶及其应用

熊敏，廖永庆，张敏，苗朝棋，蔡冬波，陈守文

《生物加工过程》

2021

代谢工程改造L-半胱氨酸供给模块促地衣芽胞杆菌高效合成杆菌肽

李凌峰，刘佩，罗文，王勤，王志，陈晓斌，李俊辉，蔡冬波，马昕，陈守文

《生物工程学报》

2021

CRISPR-Cas系统及anti-CRISPR蛋白在微生物中的研究进展

徐娜，龚云霞，邵彦春，高书山，陈守文，陈福生

《微生物学报》

2021

Effects of integrated biocontrol on bacterial wilt and rhizosphere bacterial community of tobacco

Yun Fu Hu, Yanyan Li, Xiaoqiong Yang, Chunli Li, Lin Wang, Ji Feng, Shouwen Chen, Xihong Li, Yong Yang

Scientific Reports

DOI

2021

Integrated Biological Control of Tobacco Bacterial Wilt (Ralstonia solanacearum) and Its Effect on Rhizosphere Microbial Community

Yun Fu Hu, Chunli Li, Xiaoqiong Yang, Ji Feng, Lin Wang, Shouwen Chen, Yanyan Li, Yong Guang Yang

Journal of Biosciences and Medicines

DOI

2021

Exogenous Inoculation of Microorganisms Effect on Root Exudates and Rhizosphere Microorganism of Tobaccos

Qingqing Guo, Jun Myoung Yu, Jingguo Sun, Changjun Wang, Shouwen Chen, Chunlei Yang, Yong Guang Yang

Advances in Microbiology

DOI

2021

Rational engineering of cofactor specificity of glutamate dehydrogenase for poly-γ-glutamic acid synthesis in Bacillus licheniformis

Fan Yang, Na Liu, Yaozhong Chen, Si Wang, Jun Liu, Ling Zhao, Xin Ma, Dongbo Cai, Shouwen Chen

Enzyme and Microbial Technology

DOI

2021

Metabolic Engineering of Bacillus licheniformis for Sustainable Production of Isobutanol

Yangyang Zhan, Yong Quan Xu, Xingcheng Lu, Fei Zhou, Pengling Zheng, Dong Wang, Dongbo Cai, Shihui Yang, Shouwen Chen

ACS Sustainable Chemistry & Engineering

DOI

2021

Construction and Characterization of a Gradient Strength Promoter Library for Fine-Tuned Gene Expression in Bacillus licheniformis

Yi Rao, Peifen Li, Xinxin Xie, Jiemin Li, Yongqing Liao, Xin Ma, Dongbo Cai, Shouwen Chen

ACS Synthetic Biology

DOI

2021

[Metabolic engineering of L-cysteine supply modules for enhanced production of bacitracin in Bacillus licheniformis].

Lingfeng Li, Pei Liu, Wen Luo, Qin Wang, Zhi Wang, Xiaobin Chen, Junhui Li, Dongbo Cai, Xin Ma, Shouwen Chen

PubMed

DOI

2021

Metabolic Engineering of Aspartic Acid Supply Modules for Enhanced Production of Bacitracin in Bacillus licheniformis

Jiang Zhu, Lingfeng Li, Fei Wu, Yuanxin Wu, Zhi Wang, Xiaobin Chen, Junhui Li, Dongbo Cai, Shouwen Chen

ACS Synthetic Biology

DOI

2021

A novel strategy of feeding nitrate for cost-effective production of poly-γ-glutamic acid from crude glycerol by Bacillus licheniformis WX-02

Xin Li, Haiqing Yang, Menglin Zhou, Yangyang Zhan, Jun Liu, Dazhong Yan, Dongbo Cai, Shouwen Chen

Biochemical Engineering Journal

DOI

2021

Metabolic Engineering of Central Carbon Metabolism of Bacillus licheniformis for Enhanced Production of Poly-γ-glutamic Acid

Bichan Li, Dongbo Cai, Shouwen Chen

Applied Biochemistry and Biotechnology

DOI

2021

A Two-step Strategy for High-Value-Added Utilization of Rapeseed Meal by Concurrent Improvement of Phenolic Extraction and Protein Conversion for Microbial Iturin A Production

Meng Wang, Yang Chen, Jean François, Xia Wan, Qianchun Deng, Danyang Feng, Shiyu Deng, Shouwen Chen, Fenghong Huang, Wenchao Chen, Yangmin Gong

Frontiers in Bioengineering and Biotechnology

DOI

2021

Integrated biocontrol of tobacco bacterial wilt by antagonistic bacteria and marigold

Yun Fu Hu, Wan Zhao, Xihong Li, Ji Feng, Chunli Li, Xiaoqiong Yang, Qingqing Guo, Lin Wang, Shouwen Chen, Yanyan Li, Yong Yang

Scientific Reports

DOI

2021

Improvement of 1-deoxynojirimycin production of Bacillus amyloliquefaciens by gene overexpression and medium optimization

Yu Lu, Xiangjin Cheng, Huanhuan Deng, Shouwen Chen, Zhixia Ji

LWT

DOI

2020

能量代谢工程促地衣芽胞杆菌DW2高效合成杆菌肽

张清，朱杉，崔乃香，张博闻，王志，陈晓斌，刘军，李俊辉，蔡冬波，杨之帆，陈守文，马昕

《生物工程学报》

DOI

2020

变温控制策略促进地衣芽胞杆菌合成杆菌肽

宋昭，戴航，黄雪松，陈雄，陈守文，李俊辉，王志

《湖北工业大学学报》

2020

生防菌使用方式对烟草青枯病的防效及根际土壤细菌群落的影响

黎妍妍，李春黎，王林，彭五星，杨勇，陈守文，李锡宏

《中国烟草学报》

2020

解淀粉芽孢杆菌施用方式对烟株根际土壤真菌群落的影响

黎妍妍，王林，彭五星，陈守文，杨勇，李锡宏

《中国烟草科学》

DOI

2020

The Magnesium Concentration in Yeast Extracts Is a Major Determinant Affecting Ethanol Fermentation Performance of Zymomonas mobilis

Runxia Li, Mingjie Jin, Jun Du, Mian Li, Shouwen Chen, Shihui Yang

Frontiers in Bioengineering and Biotechnology

DOI

2020

Development and characterization of acidic-pH-tolerant mutants of Zymomonas mobilis through adaptation and next-generation sequencing-based genome resequencing and RNA-Seq

Qing Yang, Yongfu Yang, Ying Tang, Xia Wang, Yunhao Chen, Wei Shen, Yangyang Zhan, Junjie Gao, Bo Wu, Mingxiong He, Shouwen Chen, Shihui Yang

Biotechnology for Biofuels

DOI

2020

Multilevel Metabolic Engineering of Bacillus amyloliquefaciens for Production of the Platform Chemical Putrescine from Sustainable Biomass Hydrolysates

Lu Li, Dian Zou, Anying Ji, Yuxuan He, Yingli Liu, Yu Deng, Shouwen Chen, Xuetuan Wei

ACS Sustainable Chemistry & Engineering

DOI

2020

Metabolic engineering of Zymomonas mobilis for anaerobic isobutanol production

Mengyue Qiu, Wei Shen, Xiongyin Yan, Qiaoning He, Dongbo Cai, Shouwen Chen, Hui Wei, Eric P. Knoshaug, Min Zhang, Michael E. Himmel, Shihui Yang

Biotechnology for Biofuels

DOI

2020

The unconventional adverse effects of fungal pretreatment on iturin A fermentation by Bacillus amyloliquefaciens CX‐20

Wenchao Chen, Meng Wang, Yangmin Gong, Qianchun Deng, Mingming Zheng, Shouwen Chen, Xia Wan, Yang Chen, Fenghong Huang

Microbial Biotechnology

DOI

2020

Efficient synthesis of 2-phenylethanol from L-phenylalanine by engineered Bacillus licheniformis using molasses as carbon source

Yangyang Zhan, Menglin Zhou, Huan Wang, Lixia Chen, Zhi Li, Dongbo Cai, Zhiyou Wen, Xin Ma, Shouwen Chen

Applied Microbiology and Biotechnology

DOI

2020

Engineering Expression Cassette of pgdS for Efficient Production of Poly-γ-Glutamic Acids With Specific Molecular Weights in Bacillus licheniformis

Dong Wang, Huan Wang, Yangyang Zhan, Yong Quan Xu, Jie Deng, Jiangang Chen, Dongbo Cai, Qin Wang, Sheng Feng, Shouwen Chen

Frontiers in Bioengineering and Biotechnology

DOI

2020

Systematic engineering of branch chain amino acid supply modules for the enhanced production of bacitracin from Bacillus licheniformis

Dongbo Cai, Jiang Zhu, Yang Li, Lingfeng Li, Meng Zhang, Zhi Wang, Hanbo Yang, Junhui Li, Zhifan Yang, Shouwen Chen

Metabolic Engineering Communications

DOI

2020

Enhanced Bacitracin Production by Systematically Engineering S-Adenosylmethionine Supply Modules in Bacillus licheniformis

Dongbo Cai, Bowen Zhang, Jiang Zhu, Haixia Xu, Pei Liu, Zhi Wang, Junhui Li, Zhifan Yang, Xin Ma, Shouwen Chen

Frontiers in Bioengineering and Biotechnology

DOI

2020

Construction and application of a dual promoter system for efficient protein production and metabolic pathway enhancement in Bacillus licheniformis

Yi Rao, Dongbo Cai, Hao Wang, Yuxiang Xu, Shijie Xiong, Lin Gao, Min Xiong, Zhi Wang, Shouwen Chen, Xin Ma

Journal of Biotechnology

DOI

2020

Multistep Metabolic Engineering of Bacillus licheniformis To Improve Pulcherriminic Acid Production

Shi‐Yi Wang, Huan Wang, Dan Zhang, Xiaoyun Li, Jiang Zhu, Yangyang Zhan, Dongbo Cai, Qin Wang, Xin Ma, Dong Wang, Shouwen Chen

Applied and Environmental Microbiology

DOI

2019

通过优化表达元件及培养基组分提高地衣芽胞杆菌中碱性丝氨酸蛋白酶产量

饶忆，师璐，王豪，熊世颉，蔡冬波，陈守文，李顺意

《微生物学通报》

DOI

2019

基于细胞碳-氮-氧需求的补料批发酵策略促进杆菌肽合成

杨华，宋昭，戴航，陈雄，李欣，陈守文，蔡冬波，李俊辉，王志

《食品与发酵工业》

DOI

2019

γ-聚谷氨酸的安全性评价(一)

张彩霞，马立保，冀志霞，荣迪，王艳青，陈守文

《食品安全质量检测学报》

2019

烟秆高效复合降解菌群的筛选、鉴定及组合应用

李春黎，李文豪，余君，孙敬国，王昌军，陈守文，杨勇

《中国烟草科学》

DOI

2019

Enhancement production of subtilisin in Bacillus licheniformis by screening promoters and signal peptides and optimization of fermentation medium

Y. Rao, Shih-Chin Lu, Hao Wang, Shi-Jie Xiong, D. Cai, Shou-Wen Chen, Shun-Yi Li

2019

Metabolic engineering of Bacillus amyloliquefaciens for enhanced production of S-adenosylmethionine by coupling of an engineered S-adenosylmethionine pathway and the tricarboxylic acid cycle

Liying Ruan, Lu Li, Dian Zou, Cong Jiang, Zhiyou Wen, Shouwen Chen, Yu Deng, Xuetuan Wei

Biotechnology for Biofuels

DOI

2019

Evaluation of the Biogenic Amines and Microbial Contribution in Traditional Chinese Sausages

Lu Li, Dian Zou, Liying Ruan, Zhiyou Wen, Shouwen Chen, Lin Xu, Xuetuan Wei

Frontiers in Microbiology

DOI

2019

Bacillus amyloliquefaciens HZ-12 heterologously expressing NdmABCDE with higher ability of caffeine degradation

Yali Jiang, Yu Lu, Youyi Huang, Shouwen Chen, Zhixia Ji

LWT

DOI

2019

Deciphering metabolic responses of biosurfactant lichenysin on biosynthesis of poly-γ-glutamic acid

Yimin Qiu, Qin Wang, Chengjun Zhu, Qing‐Qing Yang, Siyuan Zhou, Zhengwei Xiang, Shouwen Chen

Applied Microbiology and Biotechnology

DOI

2019

Prediction and characterization of promoters and ribosomal binding sites of Zymomonas mobilis in system biology era

Yongfu Yang, Wei Shen, Ju Wen Huang, Runxia Li, Yubei Xiao, Hui Wei, Yat‐Chen Chou, Min Zhang, Michael E. Himmel, Shouwen Chen, Yi Li, Lixin Ma, Shihui Yang

Biotechnology for Biofuels

DOI

2019

EngineeringBacillusfor efficient production of heterologous protein: current progress, challenge and prospect

Dongbo Cai, Y. Rao, Yangyang Zhan, Q. Wang, Shouwen Chen

Journal of Applied Microbiology

DOI

2019

Simultaneous hydrolysis with lipase and fermentation of rapeseed cake for iturin A production by Bacillus amyloliquefaciens CX-20

Wenchao Chen, Xuan Li, Xuli Ma, Shouwen Chen, Yanping Kang, Minmin Yang, Fenghong Huang, Xia Wan

BMC Biotechnology

DOI

2019

Establishment and application of multiplexed CRISPR interference system in Bacillus licheniformis

Yangyang Zhan, Yong Quan Xu, Pengling Zheng, Min He, Shanhu Sun, Dong Wang, Dongbo Cai, Xin Ma, Shouwen Chen

Applied Microbiology and Biotechnology

DOI

2019

Enhanced production of iturin A in Bacillus amyloliquefaciens by genetic engineering and medium optimization

Yuxiang Xu, Dongbo Cai, Zhang Hong, Lin Gao, Yong Yang, Jiaming Gao, Yanyan Li, Chunlei Yang, Zhixia Ji, Jun Myoung Yu, Shouwen Chen

Process Biochemistry

DOI

2019

Establishment of a rapeseed meal fermentation model for iturin A production by Bacillus amyloliquefaciens CX ‐20

Wenchao Chen, Xuli Ma, Xiuzhen Wang, Shouwen Chen, Anna Rogiewicz, B.A. Slominski, Xia Wan, Fenghong Huang

Microbial Biotechnology

DOI

2019

Modular metabolic engineering of lysine supply for enhanced production of bacitracin in Bacillus licheniformis

Fei Wu, Dongbo Cai, Lingfeng Li, Yang Li, Hanbo Yang, Junhui Li, Xin Ma, Shouwen Chen

Applied Microbiology and Biotechnology

DOI

2019

Improving the utilization rate of soybean meal for efficient production of bacitracin and heterologous proteins in the aprA-deficient strain of Bacillus licheniformis

Dongbo Cai, Bowen Zhang, Yi Rao, Lingfeng Li, Jiang Zhu, Junhui Li, Xin Ma, Shouwen Chen

Applied Microbiology and Biotechnology

DOI

2019

Metabolic Engineering of Main Transcription Factors in Carbon, Nitrogen, and Phosphorus Metabolisms for Enhanced Production of Bacitracin in Bacillus licheniformis

Dongbo Cai, Jiang Zhu, Shan Zhu, Yu Lu, Bowen Zhang, Kai Lü, Junhui Li, Xin Ma, Shouwen Chen

ACS Synthetic Biology

DOI

2019

Metabolomics analysis reveals global acetoin stress response of Bacillus licheniformis

Honglun Yuan, Yong Quan Xu, Yaozhong Chen, Yangyang Zhan, Xuetuan Wei, Lu Li, Dong Wang, Penghui He, Shengqing Li, Shouwen Chen

Metabolomics

DOI

2019

13C-Metabolic Flux Analysis Reveals the Metabolic Flux Redistribution for Enhanced Production of Poly-γ-Glutamic Acid in dlt Over-Expressed Bacillus licheniformis

Penghui He, Ni Wan, Dongbo Cai, Shiying Hu, Yaozhong Chen, Shunyi Li, Shouwen Chen

Frontiers in Microbiology

DOI

2018

防治烟草赤星病的生防菌剂田间对比试验

李锡宏，余君，陈守文，刘俊峰，黎妍妍，许汝冰

《湖北植保》

2018

地衣芽胞杆菌DW2中敲除氨基酸转运蛋白基因yhdG提高杆菌肽产量

李阳，吴非，蔡冬波，占杨杨，李俊辉，陈晓斌，陈慧超，陈守文，马昕

《生物工程学报》

2018

Biogenic amines analysis and microbial contribution in traditional fermented food of Douchi

Lu Li, Liying Ruan, Anying Ji, Zhiyou Wen, Shouwen Chen, Ling Wang, Xuetuan Wei

Scientific Reports

DOI

2018

Evaluation of the Biogenic Amines Formation and Degradation Abilities of Lactobacillus curvatus From Chinese Bacon

Lu Li, Xiaoxue Wen, Zhiyou Wen, Shouwen Chen, Ling Wang, Xuetuan Wei

Frontiers in Microbiology

DOI

2018

Progress and perspective on lignocellulosic hydrolysate inhibitor tolerance improvement in Zymomonas mobilis

Yongfu Yang, Mimi I-Nan Hu, Ying Tang, Binan Geng, Mengyue Qiu, Qiaoning He, Shouwen Chen, Xia Wang, Shihui Yang

Bioresources and Bioprocessing

DOI

2018

Effects of Tobacco Pathogens and Their Antagonistic Bacteria on Tobacco Root Exudates

Cheng Li, Jun Myoung Yu, Lu Gan, Jingguo Sun, Changjun Wang, Qin Wang, Shouwen Chen, Yong Guang Yang

Open Journal of Applied Sciences

DOI

2018

Rewiring glycerol metabolism for enhanced production of poly-γ-glutamic acid in Bacillus licheniformis

Yangyang Zhan, Bojie Sheng, Huan Wang, Jiao Shi, Dongbo Cai, Yi Li, Shihui Yang, Zhiyou Wen, Xin Ma, Shouwen Chen

Biotechnology for Biofuels

DOI

2018

Enhancement of precursor amino acid supplies for improving bacitracin production by activation of branched chain amino acid transporter BrnQ and deletion of its regulator gene lrp in Bacillus licheniformis

Jiang Zhu, Dongbo Cai, Haixia Xu, Ziwei Liu, Bowen Zhang, Fei Wu, Junhui Li, Shouwen Chen

Synthetic and Systems Biotechnology

DOI

2018

High-level production of short branched-chain fatty acids from waste materials by genetically modified Bacillus licheniformis

Jiao Shi, Yangyang Zhan, Menglin Zhou, Min He, Qin Wang, Xin Li, Zhiyou Wen, Shouwen Chen

Bioresource Technology

DOI

2018

Enhancement of Bacitracin Production by NADPH Generation via Overexpressing Glucose-6-Phosphate Dehydrogenase Zwf in Bacillus licheniformis

Shan Zhu, Dongbo Cai, Ziwei Liu, Bowen Zhang, Junhui Li, Shouwen Chen, Xin Ma

Applied Biochemistry and Biotechnology

DOI

2018

Enhanced synthesis of poly gamma glutamic acid by increasing the intracellular reactive oxygen species in the Bacillus licheniformis Δ1-pyrroline-5-carboxylate dehydrogenase gene ycgN-deficient strain

Bichan Li, Dongbo Cai, Shiying Hu, Anting Zhu, Zhili He, Shouwen Chen

Applied Microbiology and Biotechnology

DOI

2018

Enhanced production of heterologous proteins by Bacillus licheniformis with defective d-alanylation of lipoteichoic acid

Yaozhong Chen, Dongbo Cai, Penghui He, Fei Mo, Qing Zhang, Xin Ma, Shouwen Chen

World Journal of Microbiology and Biotechnology

DOI

2018

Enhanced production of poly‐γ‐glutamic acid by improving ATP supply in metabolically engineered Bacillus licheniformis

Dongbo Cai, Yaozhong Chen, Penghui He, Shi‐Yi Wang, Fei Mo, Xin Li, Qin Wang, Christopher T. Nomura, Zhiyou Wen, Xin Ma, Shouwen Chen

Biotechnology and Bioengineering

DOI

2018

[Enhanced production of bacitracin by knocking out of amino acid permease gene yhdG in Bacillus licheniformis DW2].

Yang Li, Fei Wu, Dongbo Cai, Yangyang Zhan, Junhui Li, Xiaobin Chen, Huichao Chen, Shouwen Chen, Xin Ma

PubMed

DOI

2018

Increased flux through the TCA cycle enhances bacitracin production by Bacillus licheniformis DW2

Zhaoyuan Liu, Wenli Yu, Christopher T. Nomura, Junhui Li, Shouwen Chen, Yong Yang, Qin Wang

Applied Microbiology and Biotechnology

DOI

2018

Regulation of the Synthesis and Secretion of the Iron Chelator Cyclodipeptide Pulcherriminic Acid in Bacillus licheniformis

Dong Wang, Yangyang Zhan, Dongbo Cai, Xiaoyun Li, Qin Wang, Shouwen Chen

Applied and Environmental Microbiology

DOI

2018

Enhanced Production of Poly-γ-glutamic acid by Overexpression of the Global Anaerobic Regulator Fnr in Bacillus licheniformis WX-02

Dongbo Cai, Shiying Hu, Yaozhong Chen, Li Liu, Shihui Yang, Xin Ma, Shouwen Chen

Applied Biochemistry and Biotechnology

DOI

2018

Development of an Efficient Genome Editing Tool in Bacillus licheniformis Using CRISPR-Cas9 Nickase

Kaifeng Li, Dongbo Cai, Zhangqian Wang, Zhili He, Shouwen Chen

Applied and Environmental Microbiology

DOI

2017

混合碳源对地衣芽孢杆菌发酵合成杆菌肽的影响

刘道奇，陈守文，李俊辉，陈雄，王志

《食品与发酵工业》

DOI

2017

地衣芽胞杆菌乙醛酸循环对聚谷氨酸合成的影响

田光明，游蕾，陈守文

《生物技术》

2017

抗氧化胁迫促进地衣芽孢杆菌合成杆菌肽

刘道奇，杨华，陈守文，李俊辉，陈雄，王志

《中国酿造》

2017

Microbial production of nattokinase: current progress, challenge and prospect

Dongbo Cai, Chengjun Zhu, Shouwen Chen

World Journal of Microbiology and Biotechnology

DOI

2017

Rational design and medium optimization for shikimate production in recombinant Bacillus licheniformis strains

Siqi Zuo, Jun Xiao, Yuan Zhang, Xiaodong Zhang, Christopher T. Nomura, Shouwen Chen, Qin Wang

Process Biochemistry

DOI

2017

Acetolactate synthase (AlsS) in Bacillus licheniformis WX-02: enzymatic properties and efficient functions for acetoin/butanediol and l-valine biosynthesis

Yanli Huo, Yangyang Zhan, Qin Wang, Shunyi Li, Shihui Yang, Christopher T. Nomura, Changjun Wang, Shouwen Chen

Bioprocess and Biosystems Engineering

DOI

2017

Improvement of glycerol catabolism in Bacillus licheniformis for production of poly-γ-glutamic acid

Yangyang Zhan, Chengjun Zhu, Bojie Sheng, Dongbo Cai, Qin Wang, Zhiyou Wen, Shouwen Chen

Applied Microbiology and Biotechnology

DOI

2017

Lichenysin production is improved in codY null Bacillus licheniformis by addition of precursor amino acids

Chengjun Zhu, Fang Xiao, Yimin Qiu, Qin Wang, Zhili He, Shouwen Chen

Applied Microbiology and Biotechnology

DOI

2017

Optimization of Inexpensive Agricultural By-Products as Raw Materials for Bacitracin Production in Bacillus licheniformis DW2

Qin Wang, Hui Zheng, Xia Wan, Hongfeng Huang, Junhui Li, Christopher T. Nomura, Changjun Wang, Shouwen Chen

Applied Biochemistry and Biotechnology

DOI

2017

High-level production of α-amylase by manipulating the expression of alanine racamase in Bacillus licheniformis

Penghui He, Zeying Zhang, Dongbo Cai, Yaozhong Chen, Hao Wang, Xuetuan Wei, Shunyi Li, Shouwen Chen

Biotechnology Letters

DOI

2017

Identification and High-level Production of Pulcherrimin in Bacillus licheniformis DW2

Xiaoyun Li, Dong Wang, Dongbo Cai, Yangyang Zhan, Qin Wang, Shouwen Chen

Applied Biochemistry and Biotechnology

DOI

2017

A novel strategy to improve protein secretion via overexpression of the SppA signal peptide peptidase in Bacillus licheniformis

Dongbo Cai, Hao Wang, Penghui He, Chengjun Zhu, Qin Wang, Xuetuan Wei, Christopher T. Nomura, Shouwen Chen

Microbial Cell Factories

DOI

2017

Enhancement of acetoin production from Bacillus licheniformis by 2,3-butanediol conversion strategy: Metabolic engineering and fermentation control

Lu Li, Xuetuan Wei, Wangping Yu, Zhiyou Wen, Shouwen Chen

Process Biochemistry

DOI

2017

Untangling the transcription regulatory network of the bacitracin synthase operon in Bacillus licheniformis DW2

Dong Wang, Qin Wang, Yimin Qiu, Christopher T. Nomura, Junhui Li, Shouwen Chen

Research in Microbiology

DOI

2017

A novel approach to improve poly-γ-glutamic acid production by NADPH Regeneration in Bacillus licheniformis WX-02

Dongbo Cai, Penghui He, Xingcheng Lu, Chengjun Zhu, Jiang Zhu, Yangyang Zhan, Qin Wang, Zhiyou Wen, Shouwen Chen

Scientific Reports

DOI

2017

Glutamate dehydrogenase (RocG) in Bacillus licheniformis WX-02: Enzymatic properties and specific functions in glutamic acid synthesis for poly-γ-glutamic acid production

Guangming Tian, Qin Wang, Xuetuan Wei, Xin Ma, Shouwen Chen

Enzyme and Microbial Technology

DOI

2016

地衣芽胞杆菌WX-02联产聚γ谷氨酸和2,3-丁二醇培养基的优化

占杨杨，高立，徐迪红，魏雪团，陈守文

《生物技术进展》

2016

操作シグナルペプチドとシグナルペプチダーゼによるBacillus licheniformisにおけるナットキナーゼの高レベル発現【Powered by NICT】

D. Cai, Xu Wei, Y. Qiu, Yangyang Chen, Jing-Bang Chen, Z. Wen, Shouwen Chen

2016

Use of Bacillus amyloliquefaciens HZ-12 for High-Level Production of the Blood Glucose Lowering Compound, 1-Deoxynojirimycin (DNJ), and Nutraceutical Enriched Soybeans via Fermentation

Dongbo Cai, Mengjie Liu, Xuetuan Wei, Xinmiao Li, Qin Wang, Christopher T. Nomura, Shouwen Chen

Applied Biochemistry and Biotechnology

DOI

2016

Engineering Bacillus licheniformis for the production of meso-2,3-butanediol

Yimin Qiu, Jinyan Zhang, Lu Li, Zhiyou Wen, Christopher T. Nomura, Shuilin Wu, Shouwen Chen

Biotechnology for Biofuels

DOI

2016

High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase

Dongbo Cai, Xuetuan Wei, Yunyan Qiu, Yong Chen, J. Chen, Zhiyou Wen, Shouwen Chen

Journal of Applied Microbiology

DOI

2015

烟草黑胫病生防菌的筛选、定殖及应用评价

曾衡，徐迪红，冀志霞，陈守文，魏雪团

《应用与环境生物学报》

2015

解淀粉芽孢杆菌ZM9液体发酵伊枯草菌素A培养基优化

杨代凯，陈守文，黎煊

《应用化工》

2015

Enhancement of poly‐γ‐glutamic acid production by alkaline pH stress treatment in Bacillus licheniformis WX ‐02

Jia Wang, Honglun Yuan, Xuetuan Wei, Jiangang Chen, Shouwen Chen

Journal of Chemical Technology & Biotechnology

DOI

2015

Comprehensive transcriptome and improved genome annotation of Bacillus licheniformis WX‐02

Jing Guo, Gang Cheng, Xiang-Yong Gou, Feng Xing, Sen Li, Yichao Han, Long Wang, Jia‐Ming Song, Cheng-Cheng Shu, Shouwen Chen, Ling‐Ling Chen

FEBS Letters

DOI

2015

Enhancement of l-valine production in Bacillus licheniformis by blocking three branched pathways

Chengwen Liang, Yanli Huo, Gaofu Qi, Xuetuan Wei, Qin Wang, Shouwen Chen

Biotechnology Letters

DOI

2014

烟草青枯病生防菌-22抗病机制的初步研究

杨欢，余君，王昌军，李进平，施河丽，谭军，李锡宏，王瑞，徐迪红，陈守文

《中国烟草科学》

2014

烟草赤星病拮抗芽胞杆菌的筛选及培养基优化

罗楚翔，彭建，杨欢，陈建刚，王昌军，李进平，施河丽，祁高富，陈守文

《中国烟草科学》

DOI

2014

谷氨酸对地衣芽孢杆菌产杆菌肽的影响

鲍帅帅，张默，王新平，陈雄，陈守文，李俊辉，李冬生，王志

《中国酿造》

2014

地衣芽孢杆菌WX-02补硝酸钠发酵产聚γ-谷氨酸工艺

许尚华，胡丽芳，陈守文

《湖北农业科学》

2014

一株烟草青枯病生防菌的筛选鉴定及其发酵优化

赵晓燕，杨欢，陈建刚，王昌军，冀志霞，陈守文

《湖北农业科学》

2014

Decreased Tobacco-Specific Nitrosamines by Microbial Treatment with Bacillus amyloliquefaciens DA9 during the Air-Curing Process of Burley Tobacco

Xuetuan Wei, Xiaowu Deng, Dongbo Cai, Zhixia Ji, Changjun Wang, Jun Myoung Yu, Jinping Li, Shouwen Chen

Journal of Agricultural and Food Chemistry

DOI

2014

Poly-γ-glutamic acid modified magnetic nanoparticles for fast solid phase extraction of trace amounts of Cu( ii ) and Pb( ii )

Honglun Yuan, Xuetuan Wei, Zhaorui Zeng, Daikai Yang, Shouwen Chen

Analytical Methods

DOI

2014

Efficient expression of nattokinase in Bacillus licheniformis: host strain construction and signal peptide optimization

Xuetuan Wei, Yinhua Zhou, Jingbang Chen, Dongbo Cai, Dan Wang, Gaofu Qi, Shouwen Chen

Journal of Industrial Microbiology & Biotechnology

DOI

2014

Erratum to: Physiological and metabolic analysis of nitrate reduction on poly-gamma-glutamic acid synthesis in Bacillus licheniformis WX‑02

Xin Li, Xiangyong Gou, Dan Long, Zhixia Ji, Lifang Hu, Dihong Xu, Jun Liu, Shouwen Chen

Archives of Microbiology

DOI

2014

Improvement of lichenysin production in Bacillus licheniformis by replacement of native promoter of lichenysin biosynthesis operon and medium optimization

Yimin Qiu, Fang Xiao, Xuetuan Wei, Zhiyou Wen, Shouwen Chen

Applied Microbiology and Biotechnology

DOI

2014

Physiological and metabolic analysis of nitrate reduction on poly-gamma-glutamic acid synthesis in Bacillus licheniformis WX-02

Xin Li, Xiangyong Gou, Dan Long, Zhixia Ji, Lifang Hu, Dihong Xu, Jun Liu, Shouwen Chen

Archives of Microbiology

DOI

2013

聚γ-谷氨酸对气相色谱-质谱检测地衣芽孢杆菌胞内代谢物的影响

龙丹，李欣，冀志霞，李俊辉，祁高富，陈守文

《分析科学学报》

2013

双氧水对地衣芽胞杆菌合成杆菌肽的影响

曾新年，鲍帅帅，李洪杰，陈守文，李俊辉，李冬生，王志

《中国酿造》

2012

两种启动子对聚γ-谷氨酸降解酶基因在地衣芽胞杆菌中的加强表达效果

付军涛，祁高富，刘军，冀志霞，马昕，陈守文

《应用与环境生物学报》

2012

地衣芽胞杆菌WX-02补糖发酵聚γ-谷氨酸的工艺优化

胡丽芳，李欣，冀志霞，陈守文

《华中农业大学学报》

2012

Nisin A前体基因nisA的过量表达对Nisin A产量的影响

樊苗苗，邱一敏，刘晨，冀志霞，马昕，虞沂，陈守文

《生物工程学报》

2010

胞内聚-β-羟基丁酸酯对苏云金芽胞杆菌营养细胞耐受性的影响

严瑾，陈德局，陈守文，喻子牛

《长江大学学报(自科版)农学卷》

2010

聚-γ-谷氨酸及其增效肥在水稻上的应用

刘端义，梅金先，张旅峰，魏宗林，黎银忠，张似松，柯云华，陈守文，姜玲

《湖北农业科学》

2010

聚γ-谷氨酸增效复合肥对油菜产量及其构成因素的影响

李汉涛，杨国正，柯云，陈守文

《湖北农业科学》

2010

聚-γ-谷氨酸施用对草莓产量和果实品质的影响

喻三保，张红艳，陈守文，姜玲

《湖北农业科学》

2009

生防菌枯草芽孢杆菌BS-5在3L发酵罐中的发酵工艺优化

钱风光，陈守文，蔡皓

《中国生物防治学报》

2009

溶氧对地衣芽孢杆菌DW2合成杆菌肽的影响

邓坤，冀志霞，陈守文

《中国抗生素杂志》

2009

苏云金芽胞杆菌聚γ-谷氨酸-明胶微胶囊剂制备及其抗逆性

田春华，冀志霞，吴广涛，陈守文

《应用与环境生物学报》

2008

聚γ-谷氨酸高产菌的选育与培养基优化

吴学超，曹新江，冀志霞，陈守文

《微生物学通报》

2008

豆粕的不同酶解液发酵苏云金芽孢杆菌对Zwittermicin A产量的影响

李欣，陈守文，冀志霞，喻子牛

《国外医药(抗生素分册)》

2008

枯草芽胞杆菌B6-1产拮抗物质性质的研究

王启军，陈守文，喻子牛

《湖北工程学院学报》

2008

透明颤菌血红蛋白在产聚γ-谷氨酸地衣芽胞杆菌WX-02中的表达

熊欢，魏雪团，冀志霞，孙明，陈守文

《微生物学通报》

2008

苏云金芽胞杆菌代谢网络的重构与结构分析

丁德武，刘丽，陈守文，须文波

《华中农业大学学报》

2008

植物激活蛋白Ap36在苏云金芽胞杆菌的表达及抗病作用

周臣飞，彭东海，邱德文，周康，阮丽芳，陈守文，喻子牛，孙明

《农业生物技术学报》

2008

聚-γ-谷氨酸在环境中降解特性的初步研究

陈雄，陈守文，喻子牛

《环境科学与技术》

2007

一种改进的分离纯化枯草芽胞杆菌产脂肽抗生素的方法

王启军，陈守文，喻子牛

《湖北工程学院学报》

2007

枯草芽孢杆菌ME714产聚-γ-谷氨酸固态发酵培养基的优化

吴永平，周景文，陈守文，喻子牛

《应用与环境生物学报》

2007

Zwittermicin A的分离纯化及其稳定性的初步研究

刘中信，陈守文，何进，喻子牛

《微生物学通报》

2007

枯草芽胞杆菌重组木聚糖酶基因高效表达系统的构建

王丽萍，彭德奎，陈守文，喻子牛，孙明

《农业生物技术学报》

2006

由苏云金芽胞杆菌胞晶混合物直接提取原毒素的方法

周学永，陈守文，孙宇，梁宝臣

《农业环境科学学报》，Vol. 25, No. 2

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2006

苏云金芽胞杆菌原毒素在蒙脱石上的吸附特性研究

周学永，陈守文，吴新世，黄巧云

《农业环境科学学报》，Vol. 25, No. 4

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2006

苏云金芽胞杆菌基因工程菌BMB696B对实验动物的安全性评估

彭东海，陈守文，阮丽芳，李林，喻子牛，孙明

《安全与环境学报》

2006

苏云金素发酵培养基的优化设计

常亚飞，陈守文，喻子牛

《中国生物防治学报》

2005

苏云金芽胞杆菌微滤浓缩液的流变特性

刘华亮，陈守文，孙明，喻子牛

《华中农业大学学报》

2005

苏云金芽胞杆菌不同发酵阶段的补糖发酵

张家学，陈守文，孙明，喻子牛

《食品与生物技术学报》

2003

利用整合载体构建苏云金芽胞杆菌杀虫工程菌

乐超银，孙明，陈守文，喻子牛

Journal of Genetics and Genomics

2003

我国发酵微生物农药的发展概况与趋势

朱昌雄，陈守文，刘放，杨自文，庄英萍，蒋细良

《生物加工过程》

2003

微生物农药及产业化发展

陈守文，喻子牛

《化学与生物工程》

2002

我国生物农药Bt下游技术研究中的问题及对策

周学永，陈守文

《农业环境科学学报》，Vol. 21, No. 5

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精选作品

期刊论文

谷氨酸脱羧酶pH适应性改造及全细胞催化合成γ-氨基丁酸

枯草芽胞杆菌漆酶的异源表达及催化腰果酚氧化聚合的研究

Combining expression optimization and protein engineering for high-level production of protein-glutaminase in Bacillus licheniformis

Engineering a non-oxidative glycolysis pathway in industrial Bacillus licheniformis for carbon-efficient production of acetyl-CoA derived biochemicals

System reconstruction of Bacillus licheniformis for efficient expression of alkaline protease

Development of a bifunctional dynamic control system for effective product synthesis in Bacillus licheniformis DW2

Multidimensional Metabolic Engineering for Green and Sustainable Bioproduction of Serotonin from Glucose in Bacillus licheniformis

Protein engineering combined with combinatorial optimization of critical synthetase cluster for efficient production of 1-Deoxynojirimycin in B. amyloliquefaciens

基于分子改造和宿主优化促地衣芽胞杆菌高效表达γ-谷氨酰转肽酶

Heterologous expression of keratinase SapB in Bacillus licheniformis enables efficient transformation of feather waste.

Overexpressing Endopeptidase Inhibitor IseA Enhances Biomass and Biochemical Production of Bacillus licheniformis

Unraveling the chrono-regulatory function of PhoP in nitrogen metabolism: A multi-scale engineering framework aimed at optimizing the synthesis of poly-γ-glutamic acid in Bacillus licheniformis

Cell membrane engineering of Bacillus licheniformis for the enhancement of heterologous protein production.

Efficient sustainable production of protocatechuic acid from glucose by engineered Bacillus licheniformis

Protein engineering, expression optimization, and application of alkaline protease from Alkalihalobacillus clausii FYX.

Elucidating metabolic mechanisms underlying the influence of specific growth rate on alkaline protease synthesis in Bacillus licheniformis through combined omics and computational modeling analysis

Optimizing genome editing efficiency in Streptomyces fradiae via a CRISPR/Cas9n-mediated editing system

Metabolic engineering of Bacillus licheniformis DW2 for ectoine production

饼粕肥对芽胞杆菌在烟草根际定殖及促生作用的影响

微生物法合成γ-氨基丁酸的研究进展

Understanding energy fluctuation during the transition state: The role of AbrB in Bacillus licheniformis

A new ROS response factor YvmB protects Bacillus licheniformis against oxidative stress under adverse environment

Transcription factor AbrB regulates ROS generation and clearance in Bacillus licheniformis.

Developing a Bacillus licheniformis platform for de novo production of γ-aminobutyric acid and other glutamate-derived chemicals.

Engineering Bacillus licheniformis as industrial chassis for efficient bioproduction from starch.

Synthesis of Super-High-Viscosity Poly-γ-Glutamic Acid by pgdS-Deficient Strain of Bacillus licheniformis and Its Application in Microalgae Harvesting

Modular metabolic engineering of Bacillus amyloliquefaciens for high-level production of green biosurfactant iturin A

High-level production of chitinase by multi-strategy combination optimization in Bacillus licheniformis

Engineering the Tat-secretion pathway of Bacillus licheniformis for the secretion of cytoplasmic enzyme arginase

A Convenient and Highly Efficient Strategy for Esterification of Poly (γ-Glutamic Acid) with Alkyl Halides at Room Temperature

Paradigm of engineering recalcitrant non-model microorganism with dominant metabolic pathway as a biorefinery chassis

D,L-肽链内切酶基因cwlO缺失促进地衣芽孢杆菌利用L-谷氨酰胺合成聚γ-谷氨酸

解淀粉芽胞杆菌HZ-12中ysnE参与吲哚-3-乙酸合成的代谢途径研究

基于表达元件和宿主优化促地衣芽胞杆菌高效表达L-天冬酰胺酶

Recent advances in keratinase production via protein engineering, breeding, and fermentation

High Production of Nattokinase via Fed-Batch Fermentation of the γ-PGA-Deficient Strain of Bacillus licheniformis

Development of an Inosine Hyperproducer from Bacillus licheniformis by Systems Metabolic Engineering

A novel toolbox for precise regulation of gene expression and metabolic engineering in Bacillus licheniformis

Construct a synthetic Entner–Doudoroff pathway in Bacillus licheniformis for enhancing lichenysin production

Enhancement of alkaline protease production in recombinant Bacillus licheniformis by response surface methodology

Metabolic Engineering of Bacillus licheniformis for the Bioproduction of Nicotinamide Riboside from Nicotinamide and Glucose

[Efficient production of L-asparaginase in Bacillus licheniformis by optimizing expression elements and host].

Promoting cell growth for bio-chemicals production via boosting the synthesis of L/D-alanine and D-alanyl-D-alanine in Bacillus licheniformis

Systematic Adaptation of Bacillus licheniformis to 2-Phenylethanol Stress

Enhancing the activity of disulfide-bond-containing proteins via promoting disulfide bond formation in Bacillus licheniformis

Systematic metabolic engineering of Bacillus licheniformis for hyperproduction of the antioxidant hydroxytyrosol

Metabolic engineering of Bacillus amyloliquefaciens for efficient production of α-glucosidase inhibitor1-deoxynojirimycin

Microbial synthesis of bacitracin: Recent progress, challenges, and prospects

Assembled denitrifying consortia for efficient nitrate removal under low-COD/N conditions

A cell-free artificial anabolic pathway for direct conversion of CO 2 to ethanol

DegU负调控地衣芽胞杆菌普切明酸的合成及分泌

烟草青枯病抑病型土壤中有益微生物的组成分析

Modular Engineering to Enhance Keratinase Production for Biotransformation of Discarded Feathers

Sustainable production of 2-phenylethanol from agro-industrial wastes by metabolically engineered Bacillus licheniformis

Engineered multiple translation initiation sites: a novel tool to enhance protein production in Bacillus licheniformis and other industrially relevant bacteria

Transcription factor DegU-mediated multi-pathway regulation on lichenysin biosynthesis in Bacillus licheniformis

Minimization and optimization of α-amylase terminator for heterologous protein production in Bacillus licheniformis

Enhanced production of iturin A by strengthening fatty acid synthesis modules in Bacillus amyloliquefaciens

Enhanced production of poly-γ-glutamic acid via optimizing the expression cassette of Vitreoscilla hemoglobin in Bacillus licheniformis

Enhanced aerobic denitrification performance with Bacillus licheniformis via secreting lipopeptide biosurfactant lichenysin

Multilevel metabolic engineering of Bacillus licheniformis for de novo biosynthesis of 2-phenylethanol

Mitigation of tobacco bacteria wilt with microbial degradation of phenolic allelochemicals

Genetic and metabolic engineering for poly-γ-glutamic acid production: current progress, challenges, and prospects

Metabolic engineering of Zymomonas mobilis for continuous co-production of bioethanol and poly-3-hydroxybutyrate (PHB)

合成生物学时代基于非模式细菌的工业底盘细胞研究现状与展望

土壤高效解钾菌的筛选鉴定及烟草栽培应用效果评价

重组地衣芽胞杆菌全细胞催化合成淫羊藿次苷D2

微生物产角蛋白酶及其应用

代谢工程改造L-半胱氨酸供给模块促地衣芽胞杆菌高效合成杆菌肽

CRISPR-Cas系统及anti-CRISPR蛋白在微生物中的研究进展

Effects of integrated biocontrol on bacterial wilt and rhizosphere bacterial community of tobacco

Integrated Biological Control of Tobacco Bacterial Wilt (Ralstonia solanacearum) and Its Effect on Rhizosphere Microbial Community

Exogenous Inoculation of Microorganisms Effect on Root Exudates and Rhizosphere Microorganism of Tobaccos

Rational engineering of cofactor specificity of glutamate dehydrogenase for poly-γ-glutamic acid synthesis in Bacillus licheniformis

Metabolic Engineering of Bacillus licheniformis for Sustainable Production of Isobutanol

Construction and Characterization of a Gradient Strength Promoter Library for Fine-Tuned Gene Expression in Bacillus licheniformis

[Metabolic engineering of L-cysteine supply modules for enhanced production of bacitracin in Bacillus licheniformis].

Metabolic Engineering of Aspartic Acid Supply Modules for Enhanced Production of Bacitracin in Bacillus licheniformis