百晓学者学者目录

王桂花

副教授、硕士生导师、讲师，山东农业大学

精选作品

期刊论文

2025

高校动物病理学实验课程改革探析

马兰婷，成子强，王桂花，肖一红，王刚，李超

《山东畜牧兽医》

2025

Calcium Release-Activated Calcium Modulator ORAI1-Sensitive Serine Dehydratase Regulates Fatty Acid-Induced CD4+ Th17/Treg Imbalance in Dairy Cows

Bing-Bing Zhang, Jing-Jing Wang, Ming Li, J. Wen, J. Loor, Shuang Wang, Ziwei Ji, Xinquan Lv, Guihua Wang, Cheng Xia, Wei Yang, Chuang Xu

Animals

DOI

2025

PERK-eIF2α activation by avian reticuloendotheliosis virus: a dual strategy to suppress apoptosis and aggravate immunosuppression for enhanced replication

Yitong Wang, Yike Xing, Ziqiang Cheng, Wanqing Xu, Chengui Li, Guihua Wang

Poultry Science

DOI

2025

Development of a colloidal gold-based immunochromatographic strip assay for rapid detection of Gyrovirus homsa 1 (GyH1)

Qi Yang, Ziqiang Cheng, Tianxing Yan, Guihua Wang

Journal of Virological Methods

DOI

2024

Fatty acids promote migration of CD4+ T cells through calcium release-activated calcium modulator ORAI1 sensitive glycolysis in dairy cows.

Bing-Bing Zhang, J. Wen, Ming Li, Jing-Jing Wang, Ziwei Ji, Xinquan Lv, Muhammad Usman, John Mauck, J. Loor, Wei Yang, Guihua Wang, Jin-Zhu Ma, Chuang Xu

Journal of Dairy Science

DOI

2022

Long read sequencing revealed proventricular virome of broiler chicken with transmission viral proventriculitis

Tianxing Yan, Gen Li, Defang Zhou, Liping Hu, Xiaojing Hao, Ruiqi Li, Guihua Wang, Ziqiang Cheng

BMC Veterinary Research

DOI

2022

Immunochromatographic test (ICT) for the detection of antibody against ALV-J

Guihua Wang, Yanming Wang, Ziqiang Cheng

The Thai Journal of Veterinary Medicine

DOI

2022

Marek’s disease virus serine/threonine kinase Us3 facilitates viral replication by targeting IRF7 to block IFN-β production

Xusheng Du, Defang Zhou, Jing Zhou, Jingwen Xue, Guihua Wang, Ziqiang Cheng

Veterinary Microbiology

DOI

2021

Comparative analysis of the exosomal contents of DF-1 cells infected by ALV-J

Jie Yang, Pingping Zhuang, Ziqiang Cheng, Guihua Wang

Veterinární Medicína

DOI

2020

Dynamic changes of TRIM62 distribution in REV infected chickens

Jie Yang, Ling Li, Xiaoman Wang, Ziqiang Cheng, Guihua Wang

The Thai Journal of Veterinary Medicine

DOI

2020

Infection of subgroup J avian leukosis induces erythroblasts and lymphoblasts in Chinese local breed chickens

Jie Yang, Ziqiang Cheng, Chengui Li, Guihua Wang

The Thai Journal of Veterinary Medicine

DOI

2020

TRIM62 From Chicken as a Negative Regulator of Reticuloendotheliosis Virus Replication

Ling Li, Dongyan Xu Niu, Jie Yang, Jianmin Bi, Lingjuan Zhang, Ziqiang Cheng, Guihua Wang

Frontiers in Veterinary Science

DOI

2020

Avian leukosis virus subgroup J and reticuloendotheliosis virus coinfection induced TRIM62 regulation of the actin cytoskeleton

Ling Li, Pingping Zhuang, Ziqiang Cheng, Jie Yang, Jianmin Bi, Guihua Wang

Journal of Veterinary Science

DOI

2019

TRIM62-mediated restriction of avian leukosis virus subgroup J replication is dependent on the SPRY domain

Ling Li, Weiguo Feng, Ziqiang Cheng, Jie Yang, Jianmin Bi, Xiaoman Wang, Guihua Wang

Poultry Science

DOI

2018

Outbreak of myelocytomatosis caused by mutational avian leukosis virus subgroup J in China, 2018

Defang Zhou, Jingwen Xue, Ya Zhang, Guihua Wang, Yongsheng Feng, Liping Hu, Yingli Shang, Ziqiang Cheng

Transboundary and Emerging Diseases

DOI

2018

Emergence of gyrovirus 3 in commercial broiler chickens with transmissible viral proventriculitis

Gen Li, Shiyu Yuan, HE Meng-lian, Manda Zhao, Xiaojing Hao, Minxun Song, Lingjuan Zhang, Changming Qiao, Libo Huang, Lı Zhang, Chengui Li, Guihua Wang, Ziqiang Cheng

Transboundary and Emerging Diseases

DOI

2018

Preparation and Application of a Monoclonal Antibody Against Chicken TRIM62

Xiaoman Wang, Yongzhen Zhao, Ling Li, Ziqiang Cheng, Guihua Wang

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

DOI

2018

A polyclonal antibody against extracellular loops 1 of chNHE1 blocks avian leukosis virus subgroup J infection

Wei Meng, Defang Zhou, Chengui Li, Guihua Wang, Libo Huang, Ziqiang Cheng

Research in Veterinary Science

DOI

2017

A novel multi-variant epitope ensemble vaccine against avian leukosis virus subgroup J

Xiaoyu Wang, Defang Zhou, Guihua Wang, Libo Huang, Qiankun Zheng, Chengui Li, Ziqiang Cheng

Vaccine

DOI

2017

Exosomes carring gag/env of ALV-J possess negative effect on immunocytes

Guihua Wang, Zhenzhen Wang, Pingping Zhuang, Xiaomin Zhao, Ziqiang Cheng

Microbial Pathogenesis

DOI

2017

Growth retardation induced by avian leukosis virus subgroup J associated with down-regulated Wnt/β-catenin pathway

Weiguo Feng, Defang Zhou, Wei Meng, Gen Lin Li, Pingping Zhuang, Zhifang Pan, Guihua Wang, Ziqiang Cheng

Microbial Pathogenesis

DOI

2016

禽白血病病毒J亚群跨种传播研究

申艳玮，何孟莲，张吉，赵满达，王桂花，成子强

《病毒学报》

2016

网状内皮增生症病毒感染改变外泌体蛋白质组成和免疫调节功能

庄萍萍，王小满，孟薇，李根，成子强，王桂花

《中国细胞生物学学报》

2016

Avian leukosis virus subgroup J induces its receptor--chNHE1 up-regulation

Weiguo Feng, Wei Meng, Liming Cai, Xiyao Cui, Zhifang Pan, Guihua Wang, Ziqiang Cheng

Virology Journal

DOI

2016

Identification of a variant antigenic neutralizing epitope in hypervariable region 1 of avian leukosis virus subgroup J

Minbo Hou, Defang Zhou, Gen Li, Huijun Guo, Jianzhu Liu, Guihua Wang, Qiankun Zheng, Ziqiang Cheng

Vaccine

DOI

2015

Synergistic inhibition of avian leukosis virus subgroup J replication by miRNA-embedded siRNA interference of double-target

Rongrong Wei, Xiaoqian Ma, Guihua Wang, Huijun Guo, Jianzhu Liu, Lingxiao Fan, Ziqiang Cheng

Virology Journal

DOI

2014

Chicken biliary exosomes enhance CD4+T proliferation and inhibit ALV-J replication in liver

Yue Wang, Guihua Wang, Zhenzhen Wang, Huang‐Ge Zhang, Li Zhang, Ziqiang Cheng

Biochemistry and Cell Biology

DOI

2013

Genetic mutations of avian leukosis virus subgroup J strains extended their host range

Yanwei Shen, Liming Cai, Yanming Wang, Rongrong Wei, Menglian He, Shanhui Wang, Guihua Wang, Ziqiang Cheng

Journal of General Virology

DOI

2013

Identification of two novel multiple recombinant avian leukosis viruses in two different lines of layer chicken

Liming Cai, Yanwei Shen, Guihua Wang, Huijun Guo, Jianzhu Liu, Ziqiang Cheng

Journal of General Virology

DOI

2013

Polyclonal Antibody Against Conserved Peptide in Transmembrane Protein of Avian Leukosis Virus Subgroup J

Guihua Wang, Xiaowei Wang, Qingqing Xu, Ziqiang Cheng

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

DOI

2013

Avian leukosis virus subgroup J associated with the outbreak of erythroblastosis in chickens in China

Guihua Wang, Yanping Jiang, Linin Yu, Yue Wang, Xiaomin Zhao, Ziqiang Cheng

Virology Journal

DOI

2012

禽白血病病毒J亚群自然感染商品蛋鸡致瘤性新特征

于琳琳，姜艳萍，王玥，陈洪博，王峰，王晓伟，王桂花，成子强

《畜牧兽医学报》

2012

J亚群禽白血病病毒跨膜蛋白gp37基因克隆与表达

王晓伟，刘青，徐晴晴，蔡黎明，王真真，王桂花，成子强

《病毒学报》

2012

ALV-J诱发鸡成红细胞白血病的临床病例分析

姜艳萍，王玥，于琳琳，蔡黎明，王真真，徐晴晴，王桂花，成子强

《畜牧兽医学报》

2012

New pathogenetic characters of reticuloendotheliosis virus isolated from Chinese partridge in specific-pathogen-free chickens

Guihua Wang, Yue Wang, Linlin Yu, Yanping Jiang, Jianzhu Liu, Ziqiang Cheng

Microbial Pathogenesis

DOI

2011

禽白血病病毒J亚群诱导蛋鸡群多种肿瘤

陈洪博，于琳琳，姜艳萍，王玥，王峰，王晓伟，王桂花，成子强

《畜牧兽医学报》

2010

Ana-1巨噬细胞分泌exosomes的提取及免疫鉴定

王桂花，周向梅，尹晓敏，杨利锋，周海云，张交儿，刘爱林，赵德明

《细胞与分子免疫学杂志》

2008

REV感染肉种鸡后动态病理学观察与抗原分布及检测

朱国，刁秀国，成子强，王桂花，孟祥凯，高婷婷

《中国兽医学报》

2008

Dynamic Pathology and Antigen Location Study on Broiler Breeders with Coinfection of Marek's Disease Virus and Reticuloendotheliosis Virus

Diao Xiuguo, Zhu Guo, CHENG Zi-qiang, Guihua Wang, MENG Xiang-kai, Tingting Gao, CUI Zhi-zhong

Agricultural Sciences in China

DOI

2007

转移因子纳米脂质体的制备及其体内吸收情况的观察

王桂花，高立坤，朱国，刁秀国，成子强

《中国兽医科学》

2007

冰冻切片免疫酶和免疫荧光技术快速检测REV抗原

朱国，刁秀国，成子强，王桂花，高婷婷，孟祥凯

《西南农业学报》

2007

肉种鸡马立克氏病的动态病理组织学研究

刁秀国，成子强，朱国，王桂花，孟祥凯，高婷婷

《西南农业学报》

2007

细胞因子在禽传染病防治中的应用

王桂花，成子强，高立坤，朱国，刁秀国

《动物医学进展》

预印本

2018

ALV-J and REV synergistically activate a new oncogene of KIAA1199 via NF-κB and EGFR signaling regulated by miR-147

Defang Zhou, Jingwen Xue, Pingping Zhuang, Xiyao Cui, Shuhai He, Shuai Su, Guihua Wang, Li Zhang, Chengui Li, Libo Huang, Yingli Shang, Yongxiu Yao, Venugopal Nair, Huang‐Ge Zhang, Ziqiang Cheng

bioRxiv (Cold Spring Harbor Laboratory)

DOI

研究方向

禽免疫抑制性疾病的发病机制及天然免疫蛋白抗病毒作用机制的研究外泌体在动物性疾病中的作用机制及应用

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