邹剑｜暨南大学｜学者主页

2026

药占比综合管控措施用于提升医院临床用药规范性的效果分析

宋伟正，邹剑，方静，丁劲

《中国药业》

2026

Discovery of a Potent Antisarcopenia Drug Molecular Scaffold Derived from Ligusticum chuanxiong and Its Photochemical Synthesis

Shuai Zhang, Lei Wang, Chen-Yang He, Yong-Bin Chen, Yongheng Wang, Y Li, Rong‐Rong He, Yi Ding, Xin-Luan Wang, Qing-Hua Zhou, Xin-Sheng Yao, Huan Zhao, Qin-Li Wan, Jian Zou, Hao Gao

Journal of the American Chemical Society

DOI

2025

不同产地沙棘叶提取物抗菌、抗病毒与抗炎活性的比较

张孝伦，丁肇俊，闫昌誉，李晓敏，邹剑，涂正超，王珍，栗原博，何蓉蓉，梁磊，李怡芳

《今日药学》

2025

基于AHP-TOPSIS法建立人粒细胞刺激因子注射液合理用药评价标准

宁加亮，徐可，杨梅，蒋龙扬，刘宇，邹剑，杨孝来

《中国药业》

2025

基于FAERS数据库的老年人使用三叉神经痛治疗药物的眼毒性信号挖掘研究

刘艳鑫，陈力，董长江，邹剑，何绪成，吴攀，刘靓楠，朱玲英，张了云，胡晓艺，吴玥，李根

《中国现代应用药学》

DOI

2025

洛拉替尼加重肺腺癌患者水肿一例

刘宇，黄丹，张丽容，邹剑

《临床药物治疗杂志》

2025

Corrigendum to ‘Novel ligustilide derivatives target quorum sensing system LasR/LasB and relieve inflammatory response against Pseudomonas aeruginosa infection’ [Eur J Med Chem. 263 (2024) 115972]

Jun Liu, Qiu‐Xian Chen, Wen-Fu Wu, Dong Wang, Siyu Zhao, Jiahao Li, Yiqun Chang, Shaogao Zeng, Jiayi Hu, Yujie Li, Jiaxin Du, Shu‐Meng Jiao, Hai-Chuan Xiao, Qiang Zhang, Jun Xu, Jianfu Zhao, Haibo Zhou, Yongheng Wang, Jian Zou, Pinghua Sun

European Journal of Medicinal Chemistry

DOI

2025

Chirality Determination and Anti-inflammatory Activity of Phthalide Monomers in Angelica sinensis

Shuai Zhang, Hong-Ting Luo, Ke‐Xin Fan, Chun-Xia Liu, Zhao-Han Wang, Chu-Ning Huang, Yongheng Wang, Yi-Fang Li, Rong‐Rong He, Xin-Luan Wang, Jian Zou, Xin‐Sheng Yao, Hao Gao

Journal of Natural Products

DOI

2024

基于加权TOPSIS法对阿扎司琼防治CINV合理评价方法的建立与应用

刘宇，杨小娟，黄丹，张丽，林波，邹剑，杨孝来

《中国医院药学杂志》

2024

SEC-RI-MALLS测定甘露聚糖肽分子量与分子量分布

邹剑，杨蕾，林涛，王觉晓，马晶，陈婕，李炎

《药物分析杂志》

2024

脑膜炎球菌疫苗多糖及多糖蛋白结合物分子量尺寸排阻色谱-多角度激光光散射联用检测方法的建立及验证

邹剑，杨蕾，李茂光，叶强，焦旭雯，梁蔚阳，郭中平，马晶，姚宇峰，李炎

《中国生物制品学杂志》

2024

Discovery of a Potent Antiosteoporotic Drug Molecular Scaffold Derived from Angelica sinensis and Its Bioinspired Total Synthesis

Jian Zou, Zuo-Cheng Qiu, Qiangqiang Yu, Jiaming Wu, Yongheng Wang, Ke-Da Shi, Yi-Fang Li, Rong‐Rong He, Ling Qin, Xin‐Sheng Yao, Xinluan Wang, Hao Gao

ACS Central Science

DOI

2023

县域内基层医疗机构药学服务水平提升对策研究

董长江，刘艳鑫，刘宇，邹剑

《中国药业》

2023

清热八味散致严重乏力伴恶心1例

刘宇，邹剑

《中国现代应用药学》

2023

基于FAERS的胺碘酮相关失明不良事件信号挖掘研究

刘艳鑫，董长江，邹剑，舒亚民，何绪成，吴攀，陈力

《中国现代应用药学》

2023

临床药师对1例瑞巴派特致Stevens-Johnson综合征的药学分析

龚文俊，邹剑，徐翰，边原

《中国药房》

2023

降纤酶关键质量属性研究

邹剑，李炯，杨金亮，李炎，杨蕾，马晶，袁月

《药物分析杂志》

2023

1例亚甲基四氢叶酸还原酶基因突变致甲氨蝶呤中毒的治疗实践

黄丹，邹剑，翟宗，王易，胡绍燕，周密

《中国临床药学杂志》

2023

Novel ligustilide derivatives target quorum sensing system LasR/LasB and relieve inflammatory response against Pseudomonas aeruginosa infection

Jun Liu, Qiu‐Xian Chen, Wen-Fu Wu, Dong Wang, Si-Yu Zhao, Jiahao Li, Yiqun Chang, Shao-Gao Zeng, Jia-Yi Hu, Yu-Jie Li, Jia-Xin Du, Shu‐Meng Jiao, Shu‐Meng Jiao, Qiang Zhang, Jun Xu, Jian-Fu Zhao, Zhou Hai-bo, Yongheng Wang, Jian Zou, Ping-Hua Sun

European Journal of Medicinal Chemistry

DOI

2023

Oxidative aromatization mechanism of ligustilide

Yu-Qing Zhuang, Jian Zou, Shengyuan Zhang, Jia-Ming Wu, Long Liang, Xian-Bo Chen, Guodong Chen, Dan Hu, Yongheng Wang, Hao Gao

Chemical Communications

DOI

2023

Ginsenoside Rk2, a dehydroprotopanaxadiol saponin, alleviates alcoholic liver disease via regulating NLRP3 and NLRP6 inflammasome signaling pathways in mice

Jian Zou, Rujie Yang, Rui-Bing Feng, Jia-Yue Liu, Jian-Bo Wan

Journal of Pharmaceutical Analysis

DOI

2023

Click chemistry-based enrichment strategy for tracing cellular fatty acid metabolism by LC-MS/MS

Ru-Jie Yang, Jian Zou, Jia-Yue Liu, Jiang-Kun Dai, Jian-Bo Wan

Journal of Pharmaceutical Analysis

DOI

2022

Bioactive pterocarpans from the root of Astragalus membranaceus var. mongholicus

Xue-Feng Bao, Peihong Cao, Jin Zeng, Luomin Xiao, Zhihui Luo, Jian Zou, Chuanxi Wang, Zhongxiang Zhao, Zheng-Qun Zhou, Hui Zhi, Hao Gao

Phytochemistry

DOI

2022

Catalytic role of carbonyl oxygens and water in selinadiene synthase

Yongheng Wang, Houchao Xu, Jian Zou, Xian-Bo Chen, Yu-Qing Zhuang, Weiliang Liu, Ersin Celik, Guo‐Dong Chen, Dan Hu, Hao Gao, Ruibo Wu, Ping-Hua Sun, Jeroen S. Dickschat

Nature Catalysis

DOI

2022

Red yeast rice ameliorates non-alcoholic fatty liver disease through inhibiting lipid synthesis and NF-κB/NLRP3 inflammasome-mediated hepatic inflammation in mice

Jian Zou, Chunyan Yan, Jian-Bo Wan

Chinese Medicine

DOI

2022

Extract of Ginkgo biloba leaves attenuates neurotoxic damages in rats and SH-SY5Y cells exposed to a high level of fluoride.

Jie Xiang, Yan-Lin Ma, Jian Zou, Xiao-Xiao Zeng, Xiao Xiao, Yanyiang Yu, Yang-Ting Dong, Long-Yan Ran, Xiao-lan Qi, Wei Hong, Yan-Hui Gao, Z. Guan

Journal of Trace Elements in Medicine and Biology

DOI

2021

甘露聚糖肽注射液的质量评价分析

李炎，马晶，邹剑，林涛，王觉晓，秦力，陈婕，袁军

《药学前沿》

2021

Biotransformation of α-asarone by Alternaria longipes CGMCC 3.2875

Jian Zou, Shuai Zhang, Huan ZHAO, Yong-Heng WANG, Zheng-Qun Zhou, Guo‐Dong Chen, Dan Hu, Ning LI, Xin‐Sheng Yao, Hao Gao

Chinese Journal of Natural Medicines

DOI

2021

Diisoprenyl-cyclohexene/ane-Type Meroterpenoids from Biscogniauxia sp. and Their Anti-inflammatory Activities

Huan Zhao, Jian Zou, Wei Xü, Dan Hu, Liang‐Dong Guo, Jiaxu Chen, Guo‐Dong Chen, Kwok‐Fai So, Xin‐Sheng Yao, Hao Gao

The Journal of Organic Chemistry

DOI

2020

菊三七属植物化学成分及药理活性研究进展

周青青，步真宁，王宝东，陈晶，邹剑，梁磊，高昊，何蓉蓉

《今日药学》

2020

Mechanistic Characterization of the Fusicoccane-type Diterpene Synthase for Myrothec-15(17)-en-7-ol

Fu-Long Lin, Lukas Lauterbach, Jian Zou, Yongheng Wang, Jian‐Ming Lv, Guo‐Dong Chen, Dan Hu, Hao Gao, Xin‐Sheng Yao, Jeroen S. Dickschat

ACS Catalysis

DOI

2020

Design and Optimization of 3′-(Imidazo[1,2-a]pyrazin-3-yl)-[1,1′-biphenyl]-3-carboxamides as Selective DDR1 Inhibitors

Cheng Mo, Zhang Zhang, Yupeng Li, Minhao Huang, Jian Zou, Jinfeng Luo, Zhengchao Tu, Yong Xu, Xiaomei Ren, Ke Ding, Xiaoyun Lu

ACS Medicinal Chemistry Letters

DOI

2020

Regulation of the NLRP3 inflammasome with natural products against chemical-induced liver injury.

Jian Zou, Sheng-Peng Wang, Yi-Tao Wang, Jian-Bo Wan

Pharmacological Research

DOI

2020

Reflections on treatment of COVID-19 with traditional Chinese medicine

Hua Luo, Yan Gao, Jian Zou, Siyuan Zhang, Hanbin Chen, Qiao Liu, De-Chao Tan, Yan Han, Yonghua Zhao, Sheng-Peng Wang

Chinese Medicine

DOI

2019

毛细管电泳法测定人血白蛋白和人免疫球蛋白类血液制品的纯度

李炎，林涛，邹剑，马晶，王叔桥

《药学前沿》

2019

New phthalide derivatives from the Biscogniauxia sp. and their activities

Yanying Liu, Huan Zhao, Jun Xie, Jian Zou, Dan Hu, Liang‐Dong Guo, Guo‐Dong Chen, Xin‐Sheng Yao, Hao Gao

Fitoterapia

DOI

2019

Triangeliphthalides A–D: bioactive phthalide trimers with new skeletons from Angelica sinensis and their production mechanism

Jian Zou, Guo‐Dong Chen, Huan Zhao, Xiaoxia Wang, Zaijun Zhang, Yibo Qu, Rong‐Rong He, Kwok‐Fai So, Xin‐Sheng Yao, Hao Gao

Chemical Communications

DOI

2019

Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine

Hua Luo, C. Vong, Hanbin Chen, Yan Gao, P. Lyu, Ling Qiu, Ming-Ming Zhao, Qiao Liu, Zehua Cheng, Jian Zou, Pei-Fen Yao, Caifang Gao, Jinchao Wei, C. Ung, Sheng-Peng Wang, Zhang-Feng Zhong, Yi-Tao Wang

Chinese Medicine

DOI

2019

20(S)-Protopanaxadiol Saponins Mainly Contribute to the Anti-Atherogenic Effects of Panax notoginseng in ApoE Deficient Mice

Conghui Liu, Rui-Bing Feng, Jian Zou, Fang-bo Xia, Jian-Bo Wan

Molecules

DOI

2018

Biosynthesis of an anti-tuberculosis sesterterpenoid asperterpenoid A

Jia-Hua Huang, Jian‐Ming Lv, Qiao-Zhen Wang, Jian Zou, Yongjun Lu, Qinglin Wang, Dongni Shao Chen, Xin‐Sheng Yao, Hao Gao, Dan Hu

Organic & Biomolecular Chemistry

DOI

2018

GZD2202, a novel TrkB inhibitor, suppresses BDNF-mediated proliferation and metastasis in neuroblastoma models

Jian Zou, Zhang Zhang, Fang Xu, Shengyang Cui, Chunli Qi, Jinfeng Luo, Zhen Wang, Xiaoyun Lu, Zhengchao Tu, Xiaomei Ren, Liyan Song, Ke Ding

Journal of drug targeting

DOI

2018

YL143, a novel mutant selective irreversible EGFR inhibitor, overcomes EGFRL858R, T790M‐mutant resistance in vitro and in vivo

Zhang Zhang, Jian Zou, Lei Yu, Jinfeng Luo, Yan Li, Zhengchao Tu, Xiaomei Ren, Hongcheng Wei, Liyan Song, Xiaoyun Lu, Ke Ding

Cancer Medicine

DOI

2018

Design, Synthesis, and Structure–Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitors

Qiuju Xun, Zhang Zhang, Jinfeng Luo, Linjiang Tong, Minhao Huang, Zhen Wang, Jian Zou, Yingqiang Liu, Yong Xu, Hua Xie, Zhengchao Tu, Xiaoyun Lu, Ke Ding

Journal of Medicinal Chemistry

DOI

2018

Triligustilides A and B: Two Pairs of Phthalide Trimers from Angelica sinensis with a Complex Polycyclic Skeleton and Their Activities

Jian Zou, Guo‐Dong Chen, Huan Zhao, Ying Sheng Huang, Xiang Luo, Wei Xü, Rong‐Rong He, Dan Hu, Xin‐Sheng Yao, Hao Gao

Organic Letters

DOI

2017

Bioactive Asarone-Derived Phenylpropanoids from the Rhizome of Acorus tatarinowii Schott

En Gao, Zheng-Qun Zhou, Jian Zou, Yang Yu, Xiao‐Lin Feng, Guo‐Dong Chen, Rong‐Rong He, Xin‐Sheng Yao, Hao Gao

Journal of Natural Products

DOI

2017

Phenylisotertronic acids from the TCM endophytic fungus Phyllosticta sp.

Heng-Gang Yang, Jiaojiao Li, Shao-Meng Chen, Lang-Ming Mou, Jian Zou, Chuanxi Wang, Guo‐Dong Chen, Sheng-Ying Qin, Xin‐Sheng Yao, Hao Gao

Fitoterapia

DOI

2017

Phyllomeroterpenoids A-C, Multi-biosynthetic Pathway Derived Meroterpenoids from the TCM Endophytic Fungus Phyllosticta sp. and their Antimicrobial Activities

Heng-Gang Yang, Huan Zhao, Jiaojiao Li, Shao-Meng Chen, Lang-Ming Mou, Jian Zou, Guo‐Dong Chen, Sheng-Ying Qin, Chuanxi Wang, Dan Hu, Xin‐Sheng Yao, Hao Gao

Scientific Reports

DOI

2017

Chiral resolution, absolute configuration, and bioactivity of a new racemic asarone derivative from the rhizome of Acorus tatarinowii

En Gao, Fei-Fei Ren, Jian Zou, Yang Yu, Hongxia Fan, Zheng-Qun Zhou, Guo‐Dong Chen, Rong‐Rong He, Xin‐Sheng Yao, Hao Gao

Fitoterapia

DOI

2016

Dimericbiscognienyne A: A Meroterpenoid Dimer from Biscogniauxia sp. with New Skeleton and Its Activity

Huan Zhao, Guo‐Dong Chen, Jian Zou, Rong‐Rong He, Sheng-Ying Qin, Dan Hu, Guoqiang Li, Liang‐Dong Guo, Xin‐Sheng Yao, Hao Gao

Organic Letters

DOI

2016

A set of interesting sequoiatones stereoisomers from a wetland soil-derived fungus Talaromyces flavus

Tian‐Yu Sun, Jian Zou, Guo‐Dong Chen, Dan Hu, Bin Wu, Xingzhong Liu, Xin‐Sheng Yao, Hao Gao

Acta Pharmaceutica Sinica B

DOI

2016

New cadinane sesquiterpenoids from the basidiomycetous fungus Pholiota sp.

Jie Lin, Renlei Wang, Guohua Xu, Zhengfeng Ding, Xueshen Zhu, Xingzhong Liu, Jian Zou, Guo‐Dong Chen, Li Li, Ling Liu

RSC Advances

DOI

2015

Toll样受体3在动脉粥样硬化中的作用研究进展

邹剑，刘培庆

《中国药理学与毒理学杂志》

2015

New α-pyrone and phthalide from the Xylariaceae fungus

Jian Zou, Jun Li, Zu‐Yan Wu, Qin Zhao, Gao‐Qian Wang, Huan Zhao, Guo‐Dong Chen, Xiang Sun, Liang‐Dong Guo, Hao Gao

Journal of Asian Natural Products Research

DOI

2014

顶空气相色谱法测定吐温80中的环氧乙烷与二氧六环

李炎，晁若冰，李睿，邹剑，张帆

《华西药学杂志》

2014

GC测定盐酸普拉克索中三乙胺残留量

李炎，邹剑，刘峰，李睿

《中国现代应用药学》

2013

短链脂酰辅酶A脱氢酶与心肌肥大关系的初步探索

罗佳妮，周四桂，陈少锐，陈溪，邹剑，耿彪，刘培庆

《中国药理学通报》

2009

PLGA纳米颗粒作为基因治疗载体的实验研究

叶惠平，邹剑，张懿，赵厚育，杨玉琼，刘世喜

《华西医学》

精选作品

期刊论文

药占比综合管控措施用于提升医院临床用药规范性的效果分析

Discovery of a Potent Antisarcopenia Drug Molecular Scaffold Derived from Ligusticum chuanxiong and Its Photochemical Synthesis

不同产地沙棘叶提取物抗菌、抗病毒与抗炎活性的比较

基于AHP-TOPSIS法建立人粒细胞刺激因子注射液合理用药评价标准

基于FAERS数据库的老年人使用三叉神经痛治疗药物的眼毒性信号挖掘研究

洛拉替尼加重肺腺癌患者水肿一例

Corrigendum to ‘Novel ligustilide derivatives target quorum sensing system LasR/LasB and relieve inflammatory response against Pseudomonas aeruginosa infection’ [Eur J Med Chem. 263 (2024) 115972]

Chirality Determination and Anti-inflammatory Activity of Phthalide Monomers in Angelica sinensis

基于加权TOPSIS法对阿扎司琼防治CINV合理评价方法的建立与应用

SEC-RI-MALLS测定甘露聚糖肽分子量与分子量分布

脑膜炎球菌疫苗多糖及多糖蛋白结合物分子量尺寸排阻色谱-多角度激光光散射联用检测方法的建立及验证

Discovery of a Potent Antiosteoporotic Drug Molecular Scaffold Derived from Angelica sinensis and Its Bioinspired Total Synthesis

县域内基层医疗机构药学服务水平提升对策研究

清热八味散致严重乏力伴恶心1例

基于FAERS的胺碘酮相关失明不良事件信号挖掘研究

临床药师对1例瑞巴派特致Stevens-Johnson综合征的药学分析

降纤酶关键质量属性研究

1例亚甲基四氢叶酸还原酶基因突变致甲氨蝶呤中毒的治疗实践

Novel ligustilide derivatives target quorum sensing system LasR/LasB and relieve inflammatory response against Pseudomonas aeruginosa infection

Oxidative aromatization mechanism of ligustilide

Ginsenoside Rk2, a dehydroprotopanaxadiol saponin, alleviates alcoholic liver disease via regulating NLRP3 and NLRP6 inflammasome signaling pathways in mice

Click chemistry-based enrichment strategy for tracing cellular fatty acid metabolism by LC-MS/MS

Bioactive pterocarpans from the root of Astragalus membranaceus var. mongholicus

Catalytic role of carbonyl oxygens and water in selinadiene synthase

Red yeast rice ameliorates non-alcoholic fatty liver disease through inhibiting lipid synthesis and NF-κB/NLRP3 inflammasome-mediated hepatic inflammation in mice

Extract of Ginkgo biloba leaves attenuates neurotoxic damages in rats and SH-SY5Y cells exposed to a high level of fluoride.

甘露聚糖肽注射液的质量评价分析

Biotransformation of α-asarone by Alternaria longipes CGMCC 3.2875

Diisoprenyl-cyclohexene/ane-Type Meroterpenoids from Biscogniauxia sp. and Their Anti-inflammatory Activities

菊三七属植物化学成分及药理活性研究进展

Mechanistic Characterization of the Fusicoccane-type Diterpene Synthase for Myrothec-15(17)-en-7-ol

Design and Optimization of 3′-(Imidazo[1,2-a]pyrazin-3-yl)-[1,1′-biphenyl]-3-carboxamides as Selective DDR1 Inhibitors

Regulation of the NLRP3 inflammasome with natural products against chemical-induced liver injury.

Reflections on treatment of COVID-19 with traditional Chinese medicine

毛细管电泳法测定人血白蛋白和人免疫球蛋白类血液制品的纯度

New phthalide derivatives from the Biscogniauxia sp. and their activities

Triangeliphthalides A–D: bioactive phthalide trimers with new skeletons from Angelica sinensis and their production mechanism

Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine

20(S)-Protopanaxadiol Saponins Mainly Contribute to the Anti-Atherogenic Effects of Panax notoginseng in ApoE Deficient Mice

Biosynthesis of an anti-tuberculosis sesterterpenoid asperterpenoid A

GZD2202, a novel TrkB inhibitor, suppresses BDNF-mediated proliferation and metastasis in neuroblastoma models

YL143, a novel mutant selective irreversible EGFR inhibitor, overcomes EGFRL858R, T790M‐mutant resistance in vitro and in vivo

Design, Synthesis, and Structure–Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitors

Triligustilides A and B: Two Pairs of Phthalide Trimers from Angelica sinensis with a Complex Polycyclic Skeleton and Their Activities

Bioactive Asarone-Derived Phenylpropanoids from the Rhizome of Acorus tatarinowii Schott

Phenylisotertronic acids from the TCM endophytic fungus Phyllosticta sp.

Phyllomeroterpenoids A-C, Multi-biosynthetic Pathway Derived Meroterpenoids from the TCM Endophytic Fungus Phyllosticta sp. and their Antimicrobial Activities

Chiral resolution, absolute configuration, and bioactivity of a new racemic asarone derivative from the rhizome of Acorus tatarinowii

Dimericbiscognienyne A: A Meroterpenoid Dimer from Biscogniauxia sp. with New Skeleton and Its Activity

A set of interesting sequoiatones stereoisomers from a wetland soil-derived fungus Talaromyces flavus

New cadinane sesquiterpenoids from the basidiomycetous fungus Pholiota sp.

Toll样受体3在动脉粥样硬化中的作用研究进展

New α-pyrone and phthalide from the Xylariaceae fungus

顶空气相色谱法测定吐温80中的环氧乙烷与二氧六环

GC测定盐酸普拉克索中三乙胺残留量

短链脂酰辅酶A脱氢酶与心肌肥大关系的初步探索

PLGA纳米颗粒作为基因治疗载体的实验研究

会议论文

非诺贝特通过抑制转录因子NFATc4与GATA-4及P65的结合改善压力负荷所致大鼠左心室肥厚

书籍章节

Endolichenic Fungi