郭滨｜复旦大学｜学者主页

2026

大型精密仪器在生物学实验教学中的应用实践

娄慧玲，郭滨，吴燕华

《实验室科学》

2026

CRISPR Interference to Inhibit Oncogenes for Cancer Therapy

Bin Guo

International Journal of Molecular Sciences

DOI

2026

Hyaluronic acid-coated niosomal sorafenib targets CD44 and suppresses NFκB signalling in oral squamous cell carcinoma

Ting Wu, Yong-Shu Li, Zi-Xian Wang, Bin Guo

Iranian Journal of Basic Medical Sciences

DOI

2026

Single-Chain Variable Fragment Fusion Proteins for Targeted Delivery and Therapy

Luona Yang, Yuan Yin, Xin-Li Liu, Bin Guo

Pharmaceuticals

DOI

2026

Aptamer-Based Delivery of Genes and Drugs Across the Blood–Brain Barrier

Luona Yang, Yuan Yin, Xin-Li Liu, Bin Guo

Pharmaceuticals

DOI

2026

Three-way Junction RNA Nanoparticles for Targeted Drug Delivery to Cancer

Yang-Hao Li, Xu Yang, Bin Guo

RNA Nanomed

DOI

2026

ZBTB33/RBM15 Axis Upregulates MACC1 to Promote the Malignant Progression of Colorectal Cancer.

Li-Chun Wang, Bin Guo, Xue-Ping Jiao, Quan-Mao Zhang, Sheng Gao

Current Gene Therapy

DOI

2025

Marrubiin Inhibits Cell Growth and Activating Apoptosis via Expression of Inflammatory Markers in Oral Squamous Carcinoma KB Cells

Yong-Shu Li, Bin Guo, Zi-Xian Wang, Ting Wu

Pharmacognosy Magazine

DOI

2025

Single-cell and spatial transcriptomic analysis reveal cellular heterogeneity and cancer cell-intrinsic major histocompatibility complex II expression in urothelial carcinoma

Sheng-Wei Xiong, Jian Fan, Cong Huang, Shi-Ming He, Yuan Liang, Qi Zhang, Bin Guo, Yu-Cai Wu, Man-Cheng Xia, Fangzhou Zhao, Weimin Ci, Li-Qun Zhou, Yan-Qing Gong, Xue-Song Li

International Journal on Biological Sciences

DOI

2025

GSDMD-mediated pyroptosis: molecular mechanisms, diseases and therapeutic targets

Yu-Juan Li, Bin Guo

Molecular Biomedicine

DOI

2024

Identification of vitamin D-related signature for predicting the clinical outcome and immunotherapy response in hepatocellular carcinoma

Tianyi Wang, Lulu Han, Jinjiang Xu, Bin Guo

Medicine

DOI

2024

First-Line PD-1 Blockade Combined With Chemotherapy for Stage IV Penile Squamous Cell Carcinoma: A Multicenter Retrospective Study.

L. Xiong, Xingli Shan, Huali Ma, Sheng-Jie Guo, Ji-Yan Liu, Xianda Chen, Wen-Jun Meng, Bin Guo, Li-Juan Jiang, R. Yan, X. An, Yan-Xia Shi, Yi-Jun Zhang, T. Xue, Lichao Wei, Da-Ming Xu, Zhi-Ling Zhang, Zi-Ke Qin, Kai Yao, Yajian Li, P. Spiess, Lin-Jun Hu, N. Xing, Hui Han

The Journal of the National Comprehensive Cancer Network

DOI

2024

Long Non-Coding RNA JPX Contributes to Tumorigenesis by Regulating miR-5195-3p/VEGFA in Non-Small Cell Lung Cancer [Retraction]

Guang-Liang Li, Xin-Rui Li, Chao Yuan, Cai-Cun Zhou, Xin-Xin Li, Jinfang Li, Bin Guo

Cancer Management and Research

DOI

2024

Utilizing DNA Logic Device for Precise Detection of Circulating Tumor Cells via High Catalytic Activity Au Nanoparticle Anchoring.

Bin Guo, Xiaofei Sun, Shan Tao, Tian Tian, Hao-Zhi Lei

Analytical Chemistry

DOI

2024

TClC effectively suppresses the growth and metastasis of NSCLC via polypharmacology

Jing Lu, Ying Zhang, C. Yan, Jingwen Liu, Dan Qi, Yue Zhou, Qin-Weng Wang, Jue-Chen Yang, Jing Jiang, Benhao Wu, Meiling Yang, Wei-Wei Zhang, Xin Zhang, Xiao-Yu Shi, Yan Zhang, Kun Liu, Yong-Qian Liang, Chao-Yang Wang, Hanyu Yang, Yu-Qing Gao, Yu-Ping Sun, Ronghu Ke, Jason H. Huang, Min Wu, Hong-Bo Wang, Chun-Lei Li, Shuang Zhou, Bin Guo, Er-Xi Wu, Guoying Zhang

Bioactive Materials

DOI

2024

Regulation of Cancer Metastasis by PAK2

M. Wu, Chandan Sarkar, Bin Guo

International Journal of Molecular Sciences

DOI

2024

A review on the use of extracellular vesicles for the delivery of drugs and biological therapeutics

Sundus Jabeen Amina, Tasmia Azam, Fatima Dagher, Bin Guo

Expert Opinion on Drug Delivery

DOI

2023

海分枝杆菌embA低表达菌株的构建及巨噬细胞侵染实验

李烨雨，刘含梅，黄滢睿，郭滨，张鹭

《复旦学报(自然科学版)》

2023

Identiﬁﬁcation of amino acid metabolic signature to predict prognosis and guide clinical therapy in patients with Hepatocellular carcinoma

Dalin Chen, Hui-Zhong Jiang, Bing Yang, Bin Guo, Dan Li, G. Ye, Zhu Yang, Dong-Xin Tang, Feng-Xi Long

2023

Analysis of transcriptome expression profiling data in oral leukoplakia and early and late‑stage oral squamous cell carcinoma

L. Yao, Bin Guo, Jian-Nan Wang, Jiale Wu

Oncology Letters

DOI

2023

Development and application of hepatocellular carcinoma risk prediction model based on clinical characteristics and liver related indexes

Zhi-Jie Liu, Yue Xu, Wenxiu Wang, Bin Guo, Guo-Yuan Zhang, Guang-Hui Luo, Qiang Wang

World Journal of Gastrointestinal Oncology

DOI

2023

Targeting MMP9 in CTNNB1 mutant hepatocellular carcinoma restores CD8+ T cell-mediated antitumour immunity and improves anti-PD-1 efficacy

Ning Cai, Kun Cheng, Yue Ma, Sha Liu, Ran Tao, Ya-Ni Li, Dan-Feng Li, Bin Guo, Wenlong Jia, Hui-Fang Liang, Jian-Ping Zhao, L. Xia, Ze-Yang Ding, Jinhong Chen, Wan-Guang Zhang

Gut

DOI

2022

A peptoid interleukin‐15 receptor antagonist suppresses inflammation and arthritis in mice

Kwang Bog Cho, S. Shukla, M. Kannan, Haowen Zhang, Sundus Jabeen Amina, Shuang Zhou, Yanping Chen, Jeremiah F. Molligan, V. Taneja, C. Mohan, D. Gomika Udugamasooriya, Bin Guo

Clinical & Translational Immunology

DOI

2022

Exploring synthetic lethal network for the precision treatment of clear cell renal cell carcinoma

Zhicheng Liu, Dong-Xu Lin, Yi Zhou, Lin-Meng Zhang, Chen Yang, Bin Guo, F. Xia, Yan Li, Danyang Chen, Cun Wang, Zhong Chen, Chao Leng, Zhen-Yu Xiao

Scientific Reports

DOI

2021

A Novel Peptidomimetic Therapeutic for Selective Suppression of Lung Cancer Stem Cells Over Non-stem Cancer Cells

S. Shukla, Aaron C Raymond, V. Rustagi, Samanth R Kedika, O. Tran, Liye Wang, Bin Guo, D. Gomika Udugamasooriya

Bioorganic chemistry (Print)

DOI

2021

“Molecular Masks” for ACE2 to Effectively and Safely Block SARS-CoV-2 Virus Entry

S. Shukla, Kwang Bog Cho, V. Rustagi, Xiang Gao, Xin-Ping Fu, S. Zhang, Bin Guo, D. G. Udugamasooriya

International Journal of Molecular Sciences

DOI

2020

A CRISPR-Cas9 repressor for epigenetic silencing of KRAS

Jingwen Liu, Meiyan Sun, Kwang Bog Cho, Xiang Gao, Bin Guo

Pharmacological Research

DOI

2020

Chemopreventive Agent 3,3′-Diindolylmethane Inhibits MDM2 in Colorectal Cancer Cells

Xiang Gao, Jingwen Liu, Kwang Bog Cho, Samanth R Kedika, Bin Guo

International Journal of Molecular Sciences

DOI

2020

Vitamin D Suppresses Ovarian Cancer Growth and Invasion by Targeting Long Non-Coding RNA CCAT2

Liye Wang, Shuang Zhou, Bin Guo

International Journal of Molecular Sciences

DOI

2020

Target genetic abnormalities for the treatment of colon cancer and its progression to metastasis.

Tushar S. Baviskar, Munira Momin, Jingwen Liu, Bin Guo, L. Bhatt

Current Drug Targets

DOI

2020

A Review on the Synthesis and Functionalization of Gold Nanoparticles as a Drug Delivery Vehicle

S. Amina, Bin Guo

International Journal of Nanomedicine

DOI

2019

Long Noncoding RNA (lncRNA)-Mediated Competing Endogenous RNA Networks Provide Novel Potential Biomarkers and Therapeutic Targets for Colorectal Cancer

Liye Wang, Kwang Bog Cho, Yan Li, Gabriel Tao, Zuo-Xu Xie, Bin Guo

International Journal of Molecular Sciences

DOI

2019

RNA-based therapeutics for colorectal cancer: updates and future directions

Jingwen Liu, Bin Guo

Pharmacological Research

DOI

2019

Folate-displaying exosome mediated cytosolic delivery of siRNA avoiding endosome trapping

Zhen Zheng, Zhe-Feng Li, Congcong Xu, Bin Guo, Pei-Xuan Guo

Journal of Controlled Release

DOI

2017

Nanoparticle Orientation to Control RNA Loading and Ligand Display on Extracellular Vesicles for Cancer Regression

Feng-Mei Pi, Daniel W. Binzel, T. Lee, Zhe-Feng Li, Meiyan Sun, P. Rychahou, Hui Li, F. Haque, Shaoying Wang, C. Croce, Bin Guo, B. Evers, Pei-Xuan Guo

Nature Nanotechnology

DOI

2017

Vitamin D and the Epigenetic Machinery in Colon Cancer.

Meiyan Sun, Bin Guo

Current Medicinal Chemistry

DOI

2014

线虫全基因组筛选细胞自噬活性调控基因

郭滨

《中国农业大学》

2012

从基因克隆到表达分析——改革基因工程实验课程的实践与体会

吴燕华，郭滨，娄慧玲，崔玉良，顾惠娟，乔守怡

《遗传》

2011

细胞生物学实验教学的探索与实践

娄慧玲，郭滨，吴燕华，蔡新中，田丽芬，顾惠娟，乔守怡

《高校生物学教学研究(电子版)》

精选作品

期刊论文

大型精密仪器在生物学实验教学中的应用实践

CRISPR Interference to Inhibit Oncogenes for Cancer Therapy

Hyaluronic acid-coated niosomal sorafenib targets CD44 and suppresses NFκB signalling in oral squamous cell carcinoma

Single-Chain Variable Fragment Fusion Proteins for Targeted Delivery and Therapy

Aptamer-Based Delivery of Genes and Drugs Across the Blood–Brain Barrier

Three-way Junction RNA Nanoparticles for Targeted Drug Delivery to Cancer

ZBTB33/RBM15 Axis Upregulates MACC1 to Promote the Malignant Progression of Colorectal Cancer.

Marrubiin Inhibits Cell Growth and Activating Apoptosis via Expression of Inflammatory Markers in Oral Squamous Carcinoma KB Cells

Single-cell and spatial transcriptomic analysis reveal cellular heterogeneity and cancer cell-intrinsic major histocompatibility complex II expression in urothelial carcinoma

GSDMD-mediated pyroptosis: molecular mechanisms, diseases and therapeutic targets

Identification of vitamin D-related signature for predicting the clinical outcome and immunotherapy response in hepatocellular carcinoma

First-Line PD-1 Blockade Combined With Chemotherapy for Stage IV Penile Squamous Cell Carcinoma: A Multicenter Retrospective Study.

Long Non-Coding RNA JPX Contributes to Tumorigenesis by Regulating miR-5195-3p/VEGFA in Non-Small Cell Lung Cancer [Retraction]

Utilizing DNA Logic Device for Precise Detection of Circulating Tumor Cells via High Catalytic Activity Au Nanoparticle Anchoring.

TClC effectively suppresses the growth and metastasis of NSCLC via polypharmacology

Regulation of Cancer Metastasis by PAK2

A review on the use of extracellular vesicles for the delivery of drugs and biological therapeutics

海分枝杆菌embA低表达菌株的构建及巨噬细胞侵染实验

Identiﬁﬁcation of amino acid metabolic signature to predict prognosis and guide clinical therapy in patients with Hepatocellular carcinoma

Analysis of transcriptome expression profiling data in oral leukoplakia and early and late‑stage oral squamous cell carcinoma

Development and application of hepatocellular carcinoma risk prediction model based on clinical characteristics and liver related indexes

Targeting MMP9 in CTNNB1 mutant hepatocellular carcinoma restores CD8+ T cell-mediated antitumour immunity and improves anti-PD-1 efficacy

A peptoid interleukin‐15 receptor antagonist suppresses inflammation and arthritis in mice

Exploring synthetic lethal network for the precision treatment of clear cell renal cell carcinoma

A Novel Peptidomimetic Therapeutic for Selective Suppression of Lung Cancer Stem Cells Over Non-stem Cancer Cells

“Molecular Masks” for ACE2 to Effectively and Safely Block SARS-CoV-2 Virus Entry

A CRISPR-Cas9 repressor for epigenetic silencing of KRAS

Chemopreventive Agent 3,3′-Diindolylmethane Inhibits MDM2 in Colorectal Cancer Cells

Vitamin D Suppresses Ovarian Cancer Growth and Invasion by Targeting Long Non-Coding RNA CCAT2

Target genetic abnormalities for the treatment of colon cancer and its progression to metastasis.

A Review on the Synthesis and Functionalization of Gold Nanoparticles as a Drug Delivery Vehicle

Long Noncoding RNA (lncRNA)-Mediated Competing Endogenous RNA Networks Provide Novel Potential Biomarkers and Therapeutic Targets for Colorectal Cancer

RNA-based therapeutics for colorectal cancer: updates and future directions

Folate-displaying exosome mediated cytosolic delivery of siRNA avoiding endosome trapping

Nanoparticle Orientation to Control RNA Loading and Ligand Display on Extracellular Vesicles for Cancer Regression

Vitamin D and the Epigenetic Machinery in Colon Cancer.

线虫全基因组筛选细胞自噬活性调控基因

从基因克隆到表达分析——改革基因工程实验课程的实践与体会

细胞生物学实验教学的探索与实践

会议论文

基因工程实验教学改革的探索与实践

研究方向