孙向东｜南方医科大学｜学者主页

2026

Normative Modeling of sgACC-DLPFC Functional Connectivity Identifies a Personalized rTMS Target Associated with Clinical Response in Major Depressive Disorder.

Zhan-Jie Luo, Wei-Cheng Li, Guanxi Liu, Cheng-Yu Wang, Xiao-Feng Lan, Min Zhang, Zi-Ying Chen, Jun-Hao Shen, Xuan Liu, Zhaoyi Hou, Hao Zhu, Yubing Xu, Zi-Tao Wu, Mi Zhang, Yu Yao, Muqing Zhang, Xiangdong Sun, Hanna Lu, Yan-Ling Zhou, Yu-Ping Ning

Biological Psychiatry

DOI

2026

Identifying neurophenotypes of major depressive disorder through normative model of regional homogeneity

Zhan-Jie Luo, Wei-Cheng Li, Yubing Xu, Jun-Hao Shen, Cheng-Yu Wang, Xiao-Chang Lan, Guanxi Liu, Zhan-Hui Luo, Zhaoyi Hou, S. Mai, Muqing Zhang, Xiangdong Sun, Hanna Lu, Yan-Ling Zhou, Yu-Ping Ning

Translational Psychiatry

DOI

2025

Transcriptional signatures of mitochondrial metabolism predict esketamine-induced rACC structural changes in adolescent major depression.

Yan-Ling Zhou, Wei-Cheng Li, Xiao-Feng Lan, Cheng-Yu Wang, Xiaoyu Chen, Zhan-Jie Luo, Fan Zhang, Guanxi Liu, Zi-Tao Wu, Jun-Hao Shen, Zi-Ying Chen, Hao Zhu, Xuan Liu, Yi Xue, Hanna Lu, Ji-Chun Zhang, Xiangdong Sun, K. Hashimoto, Yu-Ping Ning

Journal of the American Academy of Child and Adolescent Psychiatry

DOI

2025

ATP Release Deficiency through Astrocytic Connexin 43 in the Dorsal Hippocampus Promotes Depressive- and Anxiety-Like Behaviors

Mengling Wang, Jian Hu, Yue-Xin Wang, Xiao-Tong Lian, Yunlong Song, Dingyu Wu, Junbao Du, Hao Li, Xing-Xing Xiong, Ziming Li, Jingting Li, Yun-Shu Wang, Jiayu Hu, Xiaowen Li, Jian‐Ming Yang, Xiangdong Sun, Yi-Hua Chen, Tianming Gao

Journal of Neuroscience

DOI

2025

Altered Gut Microbiota Contributes to Acute-Respiratory-Distress-Syndrome-Related Depression through Microglial Neuroinflammation

Bowen Zhu, Zheng Gu, Hongbin Hu, Jie Huang, Zhenhua Zeng, Haoxuan Liang, Ziyi Yuan, Shiwei Huang, Yuetan Qiu, Xiangdong Sun, Youtan Liu

Research

DOI

2024

Agrin-Lrp4 pathway in hippocampal astrocytes restrains development of temporal lobe epilepsy through adenosine signaling

Ziyang Liu, Yuan‐Quan Li, Die-Lin Wang, Ying Wang, Wan-Ting Qiu, Yu-Yang Qiu, Helin Zhang, Qiang-Long You, Shi-min Liu, Qiu-Ni Liang, Er-Jian Wu, Bingjie Hu, Xiangdong Sun

Cell & Bioscience

DOI

2024

NRG1-ErbB4 signaling in the medial amygdala controls mating motivation in adult male mice

Jie Huang, Yan-Yan Zhang, Yu-Yang Qiu, Shan Yao, Wan-Ting Qiu, Jin-Lin Peng, Yuan‐Quan Li, Qiang-Long You, Cui-Hong Wu, Er-Jian Wu, Jin Wang, Yanling Zhou, Yuping Ning, Hongsheng Wang, Wenbing Chen, Bingjie Hu, Youtan Liu, Xiangdong Sun

Cell Reports

DOI

2022

Lactobacillus reuteri normalizes altered fear memory in male Cntnap4 knockout mice

Wen-Long Zhang, Jie Huang, F. Gao, Qiang-long You, Liu-Yan Ding, Junwei Gong, Meng-Ran Zhang, Runfang Ma, S. Zheng, Xiangdong Sun, Yunlong Zhang

EBioMedicine

DOI

2020

Functional validation of a human GLUD2 variant in a murine model of Parkinson’s disease

Wen-Long Zhang, Junwei Gong, Liu-Yan Ding, Zhiling Zhang, Xiaowen Pan, Xiang Chen, Wenyuan Guo, Xiao-Kang Zhang, Xin-Ling Yang, Guoyou Peng, Yu-Wan Lin, Feng Gao, Yuanquan Li, Xiao-Qin Zhu, Ai-Guo Xuan, Shu Wang, Xiangdong Sun, Yunlong Zhang, Ping-Yi Xu

Cell Death and Disease

DOI

2020

CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes

Wen-Long Zhang, Miaomiao Zhou, Wei-Ye Lu, Junwei Gong, Feng Gao, Yuanquan Li, Xuandong Xu, Yu-Wan Lin, Xiao-Kang Zhang, Liu-Yan Ding, Zhiling Zhang, Guihua Li, Xiang Chen, Xiangdong Sun, Xiao-Qin Zhu, Ping-Yi Xu, Yunlong Zhang

Theranostics

DOI

2020

Circulating metabolomics profiling reveals novel pathways associated with cognitive decline in patients with hypertension

Yu-Li Huang, Haoxiao Zheng, Kuan Tan, Xiangdong Sun, Jinshao Ye, Yunlong Zhang

Therapeutic Advances in Neurological Disorders

DOI

2020

Anti-depression effects of ketogenic diet are mediated via the restoration of microglial activation and neuronal excitability in the lateral habenula

Yanfei Guan, Guobin Huang, Min-Dong Xu, Feng Gao, Song Lin, Jie Huang, Jin Wang, Yuan‐Quan Li, Cui-Hong Wu, Shan Yao, Ying Wang, Yun‐Long Zhang, Jian‐peng Teoh, Aiguo Xuan, Xiangdong Sun

Brain Behavior and Immunity

DOI

2019

Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice

Z. Gong, Jingyi Huang, Biao Xu, Zhenri Ou, Le Zhang, Xiaohong Lin, Xiujuan Ye, Xuejian Kong, Da-Hong Long, Xiangdong Sun, Xiao-Song He, Liping Xu, Qing-Qing Li, Ai-Guo Xuan

Journal of Neuroinflammation

DOI

2019

Modified Huang-Lian-Jie-Du Decoction Ameliorates Aβ Synaptotoxicity in a Murine Model of Alzheimer's Disease

Yan Liu, Ting Du, Wen-Long Zhang, Wei-Ye Lu, Zhichao Peng, Shuqiong Huang, Xiangdong Sun, Xiao-Qin Zhu, Chaojun Chen, Lin-Chao Qian, Lei Wen, Ping-Yi Xu, Yunlong Zhang

Oxidative Medicine and Cellular Longevity

DOI

2019

Ginsenoside Rb1 regulates prefrontal cortical GABAergic transmission in MPTP-treated mice

Yan Liu, Xiaodan Zong, Jie Huang, Y. Guan, Yuanquan Li, Ting Du, Keyin Liu, Xinpan Kang, Chunyan Dou, Xiangdong Sun, Ren-Hua Wu, Lei Wen, Yunlong Zhang

Aging

DOI

2019

JAK2/STAT3 signaling mediates IL-6-inhibited neurogenesis of neural stem cells through DNA demethylation/methylation.

Xuejian Kong, Z. Gong, Le Zhang, Xiangdong Sun, Zhenri Ou, Biao Xu, Jingyi Huang, Da-Hong Long, Xiao-Song He, Xiaohong Lin, Qing-Qing Li, Liping Xu, Ai-Guo Xuan

Brain, behavior, and immunity

DOI

2017

小鼠抗人S100A9单克隆抗体可变区基因克隆及其序列分析

闫敏，米丹阳，孙向东，张振强，曾华辉，刘文第

《细胞与分子免疫学杂志》

2016

可诱导细胞凋亡的FKBP12/caspase-9慢病毒载体的构建与应用

雷艳杰，孙向东，王春荣，朱武凌，韩双印

《细胞与分子免疫学杂志》

2016

人抗P53蛋白单克隆抗体的制备及评价

宋军营，张钟允，刘文弟，曾华辉，孙向东，闫敏，袁永，翟晋豫

《免疫学杂志》

2016

鼠抗人S100A9天然蛋白单克隆抗体的制备与鉴定

米丹阳，段睿，宋军营，孙向东，张钟允，闫敏，袁永，张振强，张改平，刘文第

《中国免疫学杂志》

2014

Maintenance of GABAergic Activity by Neuregulin 1-ErbB4 in Amygdala for Fear Memory

Yisheng Lu, Xiang-Dong Sun, Fengqing Hou, Linlin Bi, Dong‐Min Yin, Fang Liu, Yongjun Chen, Jonathan Carter Bean, Hui-Feng Jiao, Xihui Liu, Bao-Ming Li, Wen‐Cheng Xiong, Tian-Ming Gao, Lin Mei

Neuron

DOI

2014

Amygdala NRG1–ErbB4 Is Critical for the Modulation of Anxiety-Like Behaviors

Linlin Bi, Xiang-Dong Sun, Jie Zhang, Yisheng Lu, Yi Hua Chen, Jue Wang, Fei Geng, Fang Liu, Meng Zhang, Jihong Liu, Xiao-Wen Li, Lin Mei, Tian Ming Gao

Neuropsychopharmacology

DOI

2013

Regulation of Spine Formation by ErbB4 in PV-Positive Interneurons

Dong‐Min Yin, Xiang-Dong Sun, Jonathan Carter Bean, Thiri W. Lin, Anupama Sathyamurthy, Wen‐Cheng Xiong, Tian-Ming Gao, Yongjun Chen, Lin Mei

Journal of Neuroscience

DOI

2010

含氢HTK液对大鼠供心保存中心肌细胞凋亡的影响

孙向东，陆方林，崔勇，徐志云

《现代生物医学进展》

孙向东

精选作品

期刊论文

Normative Modeling of sgACC-DLPFC Functional Connectivity Identifies a Personalized rTMS Target Associated with Clinical Response in Major Depressive Disorder.

Identifying neurophenotypes of major depressive disorder through normative model of regional homogeneity

Transcriptional signatures of mitochondrial metabolism predict esketamine-induced rACC structural changes in adolescent major depression.

ATP Release Deficiency through Astrocytic Connexin 43 in the Dorsal Hippocampus Promotes Depressive- and Anxiety-Like Behaviors

Altered Gut Microbiota Contributes to Acute-Respiratory-Distress-Syndrome-Related Depression through Microglial Neuroinflammation

Agrin-Lrp4 pathway in hippocampal astrocytes restrains development of temporal lobe epilepsy through adenosine signaling

NRG1-ErbB4 signaling in the medial amygdala controls mating motivation in adult male mice

Lactobacillus reuteri normalizes altered fear memory in male Cntnap4 knockout mice

Functional validation of a human GLUD2 variant in a murine model of Parkinson’s disease

CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes

Circulating metabolomics profiling reveals novel pathways associated with cognitive decline in patients with hypertension

Anti-depression effects of ketogenic diet are mediated via the restoration of microglial activation and neuronal excitability in the lateral habenula

Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice

Modified Huang-Lian-Jie-Du Decoction Ameliorates Aβ Synaptotoxicity in a Murine Model of Alzheimer's Disease

Ginsenoside Rb1 regulates prefrontal cortical GABAergic transmission in MPTP-treated mice

JAK2/STAT3 signaling mediates IL-6-inhibited neurogenesis of neural stem cells through DNA demethylation/methylation.

小鼠抗人S100A9单克隆抗体可变区基因克隆及其序列分析

可诱导细胞凋亡的FKBP12/caspase-9慢病毒载体的构建与应用

人抗P53蛋白单克隆抗体的制备及评价

鼠抗人S100A9天然蛋白单克隆抗体的制备与鉴定

Maintenance of GABAergic Activity by Neuregulin 1-ErbB4 in Amygdala for Fear Memory

Amygdala NRG1–ErbB4 Is Critical for the Modulation of Anxiety-Like Behaviors

Regulation of Spine Formation by ErbB4 in PV-Positive Interneurons

含氢HTK液对大鼠供心保存中心肌细胞凋亡的影响