张阳

2026

肿瘤微环境中Nrf2泛素化调控Hedgehog轴干预宫颈癌转移的机制

《中国优生与遗传杂志》

2026

NK细胞抗肿瘤转移的研究进展

《中国科学:生命科学》

2025

乳酸通过SRC/LDHA信号通路调节子痫前期蜕膜巨噬细胞分化

《中国免疫学杂志》

2025

胆固醇在多发性硬化症髓鞘再生中的作用:代谢调控、潜在治疗靶点与药物研究进展

《中国科学:生命科学》

2024

分子伴侣介导的自噬与肿瘤化疗耐药

《生命的化学》

DOI

2024

Intelligent Generic High‐Throughput Oscillatory Shear Technology Fabricates Programmable Microrobots for Real‐Time Visual Guidance During Embolization

Small

DOI

2024

Water‐Stable Magnetic Lipiodol Micro‐Droplets as a Miniaturized Robotic Tool for Drug Delivery

Advanced Materials

DOI

2023

BMP9通过P38 MAPK信号通路对成骨细胞自噬和凋亡的作用研究

《医学分子生物学杂志》

2023

白细胞介素-12通过抑制STAT3途径调控非小细胞肺癌细胞生物学行为及免疫逃逸因子分泌的研究

《免疫学杂志》

2023

Review of: "[Review Article] Nanocarriers for Protein and Peptide Drug Delivery"

DOI

2023

Super‐Stable Homogeneously Sustained‐Release System Mediates Transcatheter Arterial Ionic‐Embolization Strategy for Hepatocellular Carcinoma Therapy

Advanced Functional Materials

DOI

2023

Supercritical fluid technology: A game-changer for biomacromolecular nanomedicine preparation and biomedical application

Chinese Chemical Letters

DOI

2023

Super‐stable homogeneous embolic agents advance the treatment of hepatocellular carcinoma

iRadiology

DOI

2023

Innovative Design Strategies Advance Biomedical Applications of Phthalocyanines

Advanced Healthcare Materials

DOI

2023

3D Hollow Porous Radio‐Granular Hydrogels for SPECT Imaging‐Guided Cancer Intravascular Brachytherapy

Advanced Functional Materials

DOI

2022

Fast and accurate Ab Initio Protein structure prediction using deep learning potentials

PLoS Comput. Biol.

DOI

2022

GPU-I-TASSER: a GPU accelerated I-TASSER protein structure prediction tool

Bioinform.

DOI

2022

Accurate flexible refinement for atomic-level protein structure using cryo-EM density maps and deep learning

Briefings Bioinform.

DOI

2022

Predicting Protein-Ligand Binding Affinity via Joint Global-Local Interaction Modeling

Industrial Conference on Data Mining

DOI

2022

An exploratory human study of superstable homogeneous lipiodol–indocyanine green formulation for precise surgical navigation in liver cancer

Bioengineering & Translational Medicine

DOI

2021

Decoding the link of microbiome niches with homologous sequences enables accurately targeted protein structure prediction

Proceedings of the National Academy of Sciences of the United States of America

DOI

2021

ADDRESS: A database of disease-associated human variants incorporating protein structure and folding stabilities

Journal of Molecular Biology

DOI

2021

Deep learning techniques have significantly impacted protein structure prediction and protein design

Current Opinion in Structural Biology

DOI

2021

Toward the solution of the protein structure prediction problem

Journal of Biological Chemistry

DOI

2021

Improving fragment-based ab initio protein structure assembly using low-accuracy contact-map predictions

Nature Communications

DOI

2021

Protein structure prediction using deep learning distance and hydrogen-bonding restraints in CASP14

Proteins: Structure, Function, and Bioinformatics

DOI

2021

MPDB: a unified multi-domain protein structure database integrating structural analogue detection

bioRxiv

DOI

2021

Decoding microbiome and protein family linkage to improve protein structure prediction

bioRxiv

DOI

2021

MMpred: a distance-assisted multimodal conformation sampling for de novo protein structure prediction

bioRxiv

DOI

2021

Identification of 13 Guanidinobenzoyl- or Aminidinobenzoyl-Containing Drugs to Potentially Inhibit TMPRSS2 for COVID-19 Treatment

International Journal of Molecular Sciences

DOI

2021

Computational analysis of vertebrate myoglobins reveals aggregation resistance in aquatic birds and higher surface hydrophobicity in fish

DOI

2021

TripletGO: Integrating Transcript Expression Profiles with Protein Homology Inferences for High-Accuracy Gene Function Annotations

bioRxiv

DOI

2021

Protein inter-residue contact and distance prediction by coupling complementary coevolution features with deep residual networks in CASP14

Proteins: Structure, Function, and Bioinformatics

DOI

2021

Functions of Essential Genes and a Scale-Free Protein Interaction Network Revealed by Structure-Based Function and Interaction Prediction for a Minimal Genome

Journal of Proteome Research

DOI

2021

PEPPI: Whole-proteome protein-protein interaction prediction through structure and sequence similarity, functional association, and machine learning

bioRxiv

DOI

2021

Fitting Low-Resolution Protein Structures into Cryo-EM Density Maps by Multiobjective Optimization of Global and Local Correlations.

Journal of Physical Chemistry B

DOI

2021

Protein structural features predict responsiveness to pharmacological chaperone treatment for three lysosomal storage disorders

bioRxiv

DOI

2021

Folding non-homologous proteins by coupling deep-learning contact maps with I-TASSER assembly simulations

Cell Reports Methods

DOI

2021

Design, fabrication and application of magnetically actuated micro/nanorobots: a review

Nanotechnology

DOI

2020

SRC-1基因在小鼠神经干细胞分化过程中的变化

《中国药理学通报》

2020

Virtual screening of human Class-A GPCRs using ligand profiles built on multiple ligand-receptor interactions

Journal of Molecular Biology

DOI

2020

A new protocol for atomic-level protein structure modeling and refinement using low-to-medium resolution cryo-EM density maps

Journal of Molecular Biology

DOI

2020

Genome-wide structure and function modeling of SARS-COV-2

DOI

2020

FASPR: an open-source tool for fast and accurate protein side-chain packing

Bioinform.

DOI

2020

Deducing high-accuracy protein contact-maps from a triplet of coevolutionary matrices through deep residual convolutional networks

bioRxiv

DOI

2020

Landscape of variable domain of heavy‐chain‐only antibody repertoire from alpaca

Immunology

DOI

2020

Computational design of SARS-CoV-2 spike glycoproteins to increase immunogenicity by T cell epitope engineering

Computational and Structural Biotechnology Journal

DOI

2020

FUpred: detecting protein domains through deep-learning-based contact map prediction

Bioinform.

DOI

2020

Integrating multimeric threading with high-throughput experiments for structural interactome of Escherichia coli

bioRxiv

DOI

2020

Identifying the Zoonotic Origin of SARS-CoV-2 by Modeling the Binding Affinity Between the Spike Receptor-Binding Domain and Host ACE2

Journal of Proteome Research

DOI

2020

Accurate multistage prediction of protein crystallization propensity using deep-cascade forest with sequence-based features

Briefings Bioinform.

DOI

2020

EDock: blind protein–ligand docking by replica-exchange monte carlo simulation

Journal of Cheminformatics

DOI

2020

De novo design of protein peptides to block association of the SARS-CoV-2 spike protein with human ACE2

Aging

DOI

2020

Progressive and accurate assembly of multi-domain protein structures from cryo-EM density maps

bioRxiv

DOI

2020

Detecting Gene Ontology misannotations using taxon-specific rate ratio comparisons

Bioinform.

DOI

2020

Protein structure and sequence re-analysis of 2019-nCoV genome does not indicate snakes as its intermediate host or the unique similarity between its spike protein insertions and HIV-1

bioRxiv

DOI

2020

Effects of SARS‐CoV‐2 mutations on protein structures and intraviral protein–protein interactions

bioRxiv

DOI

2020

Activatable NIR‐II Plasmonic Nanotheranostics for Efficient Photoacoustic Imaging and Photothermal Cancer Therapy

Advanced Materials

DOI

2020

Multi‐Responsive Bottlebrush‐Like Unimolecules Self‐Assembled Nano‐Riceball for Synergistic Sono‐Chemotherapy

Small Methods

DOI

2020

Bio-engineered cell membrane nanovesicles as precision theranostics for perihilar cholangiocarcinoma

Biomaterials Science

DOI

2019

Tim-3对肝癌干细胞自我更新能力的调控以及对TGF-β1/smad4通路的影响

《药学前沿》

2019

鸟嘌呤核苷酸结合蛋白3通过JNK和ERK信号通路促进根尖牙乳头干细胞的成牙/成骨分化

《南京医科大学》

2019

EvoDesign: Designing protein-protein binding interactions using evolutionary interface profiles in conjunction with an optimized physical energy function

Journal of Molecular Biology

DOI

2019

Assembling multidomain protein structures through analogous global structural alignments

Proceedings of the National Academy of Sciences of the United States of America

DOI

2019

DAMpred: Recognizing disease-associated nsSNPs through Bayes-guided neural-network model built on low-resolution structure prediction of proteins and protein-protein interactions

Journal of Molecular Biology

DOI

2019

Changing the Apoptosis Pathway through Evolutionary Protein Design

Journal of Molecular Biology

DOI

2019

Artificial intelligence-based multi-objective optimization protocol for protein structure refinement

Bioinform.

DOI

2019

Structural and ligand binding analyses of the periplasmic sensor domain of RsbU in Chlamydia trachomatis supports role in TCA cycle regulation

Molecular Microbiology

DOI

2019

Precise modelling and interpretation of bioactivities of ligands targeting G protein-coupled receptors

Bioinform.

DOI

2019

I-TASSER gateway: A protein structure and function prediction server powered by XSEDE

Future generations computer systems

DOI

2019

Interpreting the Dynamics of Binding Interactions of snRNA and U1A Using a Coarse-Grained Model.

Biophysical Journal

DOI

2019

LabCaS for Ranking Potential Calpain Substrate Cleavage Sites from Amino Acid Sequence.

Methods in molecular biology

DOI

2019

Blinded Testing of Function Annotation for uPE1 Proteins by I-TASSER/COFACTOR Pipeline Using the 2018–2019 Additions to neXtProt and the CAFA3 Challenge

Journal of Proteome Research

DOI

2019

Changing the Ap Evolutionary Pro

2019

Underestimation-Assisted Global-Local Cooperative Differential Evolution and the Application to Protein Structure Prediction

IEEE Transactions on Evolutionary Computation

DOI

2019

SSIPe: accurately estimating protein-protein binding affinity change upon mutations using evolutionary profiles in combination with an optimized physical energy function

Bioinform.

DOI

2019

LOMETS2: improved meta-threading server for fold-recognition and structure-based function annotation for distant-homology proteins

Nucleic Acids Res.

DOI

2019

Function Prediction for G Protein-Coupled Receptors through Text Mining and Induction Matrix Completion

ACS Omega

DOI

2019

RNA-align: quick and accurate alignment of RNA 3D structures based on size-independent TM-scoreRNA

Bioinform.

DOI

2019

Detecting distant-homology protein structures by aligning deep neural-network based contact maps

PLoS Comput. Biol.

DOI

2019

Changing the Ap through Evolutio

2019

gnizing Disease-Associated Bayes-Guided Neural-uilt on Low-Resolution tion of Proteins and Interactions

2019

Ensembling multiple raw coevolutionary features with deep residual neural networks for contact-map prediction in CASP13

Proteins: Structure, Function, and Bioinformatics

DOI

2019

ResPRE: high-accuracy protein contact prediction by coupling precision matrix with deep residual neural networks

Bioinform.

DOI

2019

Fueling ab initio folding with marine metagenomics enables structure and function predictions of new protein families

Genome Biology

DOI

2019

The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens

Genome Biology

DOI

2019

DeepMSA: constructing deep multiple sequence alignment to improve contact prediction and fold-recognition for distant-homology proteins

Bioinform.

DOI

2019

CGLFold: a contact-assisted de novo protein structure prediction using global exploration and loop perturbation sampling algorithm

Bioinform.

DOI

2019

Cryo-EM Density Map Fitting Driven In-Silico Structure of Human Soluble Guanylate Cyclase (hsGC) reveals functional aspects of inter-domain cross talk upon NO binding

Journal of Molecular Graphics and Modelling

DOI

2019

Deep-learning contact-map guided protein structure prediction in CASP13

Proteins: Structure, Function, and Bioinformatics

DOI

2019

DockRMSD: an open-source tool for atom mapping and RMSD calculation of symmetric molecules through graph isomorphism

Journal of Cheminformatics

DOI

2019

OP-CBIO190748 1..8

2019

EvoEF2: accurate and fast energy function for computational protein design

Bioinform.

DOI

2019

Toward the Accuracy and Speed of Protein Side-Chain Packing: A Systematic Study on Rotamer Libraries

Journal of Chemical Information and Modeling

DOI

2019

Sono‐Immunotherapeutic Nanocapturer to Combat Multidrug‐Resistant Bacterial Infections

Advanced Materials

DOI

2019

Genetically Engineered Cell Membrane Nanovesicles for Oncolytic Adenovirus Delivery: A Versatile Platform for Cancer Virotherapy

Nano Letters

DOI

2018

MetaGO: Predicting Gene Ontology of non-homologous proteins through low-resolution protein structure prediction and protein-protein network mapping

Journal of Molecular Biology

DOI

2018

Recent advances in automated protein design and its future challenges

Expert Opinion on Drug Discovery

DOI

2018

mTM-align: a server for fast protein structure database search and multiple protein structure alignment

Nucleic Acids Res.

DOI

2018

ATPbind: Accurate Protein–ATP Binding Site Prediction by Combining Sequence-Profiling and Structure-Based Comparisons

Journal of Chemical Information and Modeling

DOI

2018

THE-DB: a threading model database for comparative protein structure analysis of the E. coli K12 and human proteomes

Database J. Biol. Databases Curation

DOI

2018

The structure of the large regulatory α subunit of phosphorylase kinase examined by modeling and hydrogen‐deuterium exchange

Protein Science

DOI

2018

MR-REX: molecular replacement by cooperative conformational search and occupancy optimization on low-accuracy protein models.

Acta Crystallographica Section D: Structural Biology

DOI

2018

WDL‐RF: predicting bioactivities of ligand molecules acting with G protein‐coupled receptors by combining weighted deep learning and random forest

Bioinform.

DOI

2018

mTM‐align: an algorithm for fast and accurate multiple protein structure alignment

Bioinform.

DOI

2018

MetaGO : Predict Non-homologou Low-Resolution Prediction and P Network Mappin

2018

MetaGO : Predicting Gene Ontology of Non-hom Resolutio Protein – P

2018

An analysis and evaluation of the WeFold collaborative for protein structure prediction and its pipelines in CASP11 and CASP12

Scientific Reports

DOI

2018

LS‐align: an atom‐level, flexible ligand structural alignment algorithm for high‐throughput virtual screening

Bioinform.

DOI

2018

COACH-D: improved protein–ligand binding sites prediction with refined ligand-binding poses through molecular docking

Nucleic Acids Res.

DOI

2018

A single-step multi-level supramolecular system for cancer sonotheranostics

Nanoscale Horizons

DOI

2018

Magnetosome Modification: From Bio‐Nano Engineering Toward Nanomedicine

Advanced Therapeutics

DOI

2017

Approaches to ab initio molecular replacement of α-helical transmembrane proteins

Acta Crystallographica Section D: Structural Biology

DOI

2017

Template-based and free modeling of I-TASSER and QUARK pipelines using predicted contact maps in CASP12

Proteins: Structure, Function, and Bioinformatics

DOI

2017

NeBcon: protein contact map prediction using neural network training coupled with naïve Bayes classifiers

Bioinform.

DOI

2017

Protein structure prediction

International Journal of Modern Physics B

DOI

2017

Annotation of Alternatively Spliced Proteins and Transcripts with Protein-Folding Algorithms and Isoform-Level Functional Networks

Methods in molecular biology

DOI

2017

Protein–Protein Interactions and Genetic Disease

DOI

2017

Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework

Genome Medicine

DOI

2017

COFACTOR: improved protein function prediction by combining structure, sequence and protein–protein interaction information

Nucleic Acids Res.

DOI

2017

An Evolution-Based Approach to De Novo Protein Design

Methods in molecular biology

DOI

2017

Genetically Engineered Liposome‐like Nanovesicles as Active Targeted Transport Platform

Advanced Materials

DOI

2017

Metalla-aromatic loaded magnetic nanoparticles for MRI/photoacoustic imaging-guided cancer phototherapy

Journal of Materials Chemistry B

DOI

2017

Rücktitelbild: Remote Regulation of Membrane Channel Activity by Site‐Specific Localization of Lanthanide‐Doped Upconversion Nanocrystals (Angew. Chem. 11/2017)

Angewandte Chemie

DOI

2017

Back Cover: Remote Regulation of Membrane Channel Activity by Site‐Specific Localization of Lanthanide‐Doped Upconversion Nanocrystals (Angew. Chem. Int. Ed. 11/2017)

Angewandte Chemie International Edition

DOI

2017

Remote Regulation of Membrane Channel Activity by Site‐Specific Localization of Lanthanide‐Doped Upconversion Nanocrystals

Angewandte Chemie

DOI

2016

BindProfX: Assessing Mutation-Induced Binding Affinity Change by Protein Interface Profiles with Pseudo-Counts

Journal of Molecular Biology

DOI

2016

STRUM: structure-based prediction of protein stability changes upon single-point mutation

Bioinform.

DOI

2016

Recognizing metal and acid radical ion-binding sites by integrating ab initio modeling with template-based transferals

Bioinform.

DOI

2016

Approach to the unfolding and folding dynamics of add A-riboswitch upon adenine dissociation using a coarse-grained elastic network model.

Journal of Chemical Physics

DOI

2016

A Network of Splice Isoforms for the Mouse

Scientific Reports

DOI

2016

Modeling structure of G protein-coupled receptors in huan genome

2016

3DRobot: automated generation of diverse and well-packed protein structure decoys

Bioinform.

DOI

2016

Gadolinium hybrid iron oxide nanocomposites for dual T 1 - and T 2 -weighted MR imaging of cell labeling

Biomaterials Science

DOI

2015

慢病毒介导新型Tet-On系统调控大鼠GDNF和TH双基因表达对帕金森病大鼠的实验研究

《中国药理学通报》

2015

ResQ: An approach to unified estimation of B-factor and residue-specific error in protein structure prediction

Journal of Molecular Biology

DOI

2015

GPCR-I-TASSER: A hybrid approach to G protein-coupled receptor structure modeling and the application to the human genome

Structure

DOI

2015

Structural Bioinformatics Inspection of neXtProt PE5 Proteins in the Human Proteome

Journal of Proteome Research

DOI

2015

Template-based protein structure prediction in CASP11 and retrospect of I-TASSER in the last decade

Proteins: Structure, Function, and Bioinformatics

DOI

2015

Integration of QUARK and I-TASSER for ab initio protein structure prediction in CASP11

Proteins: Structure, Function, and Bioinformatics

DOI

2015

Improving accuracy of protein contact prediction using balanced network deconvolution

Proteins: Structure, Function, and Bioinformatics

DOI

2015

PCalign: a method to quantify physicochemical similarity of protein-protein interfaces

BMC Bioinformatics

DOI

2015

Protein Structure and Function Prediction Using I-TASSER

Current Protocols in Bioinformatics

DOI

2015

I-TASSER server: new development for protein structure and function predictions

Nucleic Acids Res.

DOI

2015

Functional Networks of Highest-Connected Splice Isoforms: From The Chromosome 17 Human Proteome Project

Journal of Proteome Research

DOI

2015

Exploring the speed and performance of molecular replacement with AMPLE using QUARK ab initio protein models

Acta Crystallographica Section D: Biological Crystallography

DOI

2015

NMR data-driven structure determination using NMR-I-TASSER in the CASD-NMR experiment

Journal of Biomolecular NMR

DOI

2015

Accurate disulfide-bonding network predictions improve ab initio structure prediction of cysteine-rich proteins

Bioinform.

DOI

2015

Crystal structure of designed PX domain from cytokine-independent survival kinase and implications on evolution-based protein engineering

Journal of Structural Biology

DOI

2015

GLASS: a comprehensive database for experimentally validated GPCR-ligand associations

Bioinform.

DOI

2015

Predicting the Effect of Mutations on Protein-Protein Binding Interactions through Structure-Based Interface Profiles

PLoS Comput. Biol.

DOI

2014

The I-TASSER Suite: protein structure and function prediction

Nature Methods

DOI

2014

Protein structure prediction provides comparable performance to crystallographic structures in docking-based virtual screening

Methods

DOI

2014

Modeling the functional relationship network at the splice isoform level through heterogeneous data integration

bioRxiv

DOI

2013

Structure Prediction and Analysis of DNA Transposon and LINE Retrotransposon Proteins*

Journal of Biological Chemistry

DOI

2013

Turning gold into ‘junk’: transposable elements utilize central proteins of cellular networks

Nucleic Acids Research

DOI

2013

Template-based structure modeling of protein-protein interactions

Current Opinion in Structural Biology

DOI

2013

EvoDesign: de novo protein design based on structural and evolutionary profiles

Nucleic Acids Res.

DOI

2013

The illustration of random-walk ideal chain model and the relationship with real protein chain.

DOI

2013

High-accuracy prediction of transmembrane inter-helix contacts and application to GPCR 3D structure modeling

Bioinform.

DOI

2013

Modeling, Ion Conductance, and Electrostatic Properties of the Protective Antigen Pore Structure of Anthrax Toxin

DOI

2013

Protein Depth Calculation and the Use for Improving Accuracy of Protein Fold Recognition

J. Comput. Biol.

DOI

2013

Interplay of I-TASSER and QUARK for template-based and ab initio protein structure prediction in CASP10

Proteins: Structure, Function, and Bioinformatics

DOI

2013

An Evolution-Based Approach to De Novo Protein Design and Case Study on Mycobacterium tuberculosis

PLoS Comput. Biol.

DOI

2013

Fast and Accurate Calculation of Protein Depth by Euclidean Distance Transform

Annual International Conference on Research in Computational Molecular Biology

DOI

2013

A comparative assessment and analysis of 20 representative sequence alignment methods for protein structure prediction

Scientific Reports

DOI

2013

Author response: Super Spy variants implicate flexibility in chaperone action

DOI

2013

Mapping Monomeric Threading to Protein–Protein Structure Prediction

Journal of Chemical Information and Modeling

DOI

2013

Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment

Bioinform.

DOI

2013

Ab Initio structure prediction for Escherichia coli: towards genome-wide protein structure modeling and fold assignment

Scientific Reports

DOI

2013

SPARCS: a web server to analyze (un)structured regions in coding RNA sequences

Nucleic Acids Res.

DOI

2013

Innovations in Proteomic Profiling of Cancers: Alternative Splice Variants as a New Class of Cancer Biomarker Candidates and Bridging of Proteomics with Structural Biology

Journal of Proteomics

DOI

2013

Illustrative examples of the EBM design on M. tuberculosis proteins.

DOI

2013

Segment assembly, structure alignment and iterative simulation in protein structure prediction

BMC Biology

DOI

2012

Structure and Location of the Regulatory β Subunits in the (αβγδ)4 Phosphorylase Kinase Complex* ♦

Journal of Biological Chemistry

DOI

2012

Structural homology modeling and mutant cycle analysis predict pharmacoresponsiveness of a NaV1.7 mutant channel

Nature Communications

DOI

2012

Protein Structure Prediction

DOI

2012

Ab Initio Protein Structure Assembly Using Continuous Structure Fragments and Optimized Knowledge-based Force Field

Proteins: Structure, Function, and Bioinformatics

DOI

2012

How Many Protein-Protein Interactions Types Exist in Nature?

PLoS ONE

DOI

2012

COFACTOR: an accurate comparative algorithm for structure-based protein function annotation

Nucleic Acids Res.

DOI

2012

LabCaS: Labeling calpain substrate cleavage sites from amino acid sequence using conditional random fields

Proteins: Structure, Function, and Bioinformatics

DOI

2012

What is the best reference state for designing statistical atomic potentials in protein structure prediction?

Proteins: Structure, Function, and Bioinformatics

DOI

2012

Toward optimal fragment generations for ab initio protein structure assembly

Proteins: Structure, Function, and Bioinformatics

DOI

2012

Recognizing protein-ligand binding sites by global structural alignment and local geometry refinement

Structure

DOI

2012

BioLiP: a semi-manually curated database for biologically relevant ligand–protein interactions

Nucleic Acids Res.

DOI

2011

慢病毒介导的新型Tet-On系统大鼠GDNF和TH双基因脑内转移对帕金森病大鼠模型的保护作用

《中国药理学通报》

2011

Intra-chain 3D Segment Swapping Spawns the Evolution of New Multidomain Protein Architectures

Journal of Molecular Biology

DOI

2011

Computational Protein Design and Large-Scale Assessment by I-TASSER Structure Assembly Simulations

Journal of Molecular Biology

DOI

2011

Automated protein structure modeling in CASP9 by I-TASSER pipeline combined with QUARK-based ab initio folding and FG-MD-based structure refinement

Proteins: Structure, Function, and Bioinformatics

DOI

2011

Prediction Methods and Reports

2011

BSP-SLIM: A Blind Low-Resolution Ligand-Protein Docking Approach Using Predicted Protein Structures

Proteins: Structure, Function, and Bioinformatics

DOI

2011

Improving protein template recognition by using small-angle x-ray scattering profiles.

Biophysical Journal

DOI

2011

Functional Implications of Structural Predictions for Alternative Splice Proteins Expressed in Her2/neu–Induced Breast Cancers

Journal of Proteome Research

DOI

2011

PROTS: A fragment based protein thermo-stability potential

Proteins: Structure, Function, and Bioinformatics

DOI

2011

Protein-protein complex structure predictions by multimeric threading and template recombination

Structure

DOI

2011

Predicting nucleic acid binding interfaces from structural models of proteins

Proteins: Structure, Function, and Bioinformatics

DOI

2011

Protein Homology Analysis for Function Prediction with Parallel Sub-Graph Isomorphism

DOI

2011

Genome-Wide Protein Structure Prediction

DOI

2011

A Protocol for Computer-Based Protein Structure and Function Prediction

Journal of Visualized Experiments

DOI

2011

Parkin, A Top Level Manager in the Cell’s Sanitation Department

Open Biochemistry Journal

DOI

2011

Improving protein structure prediction using multiple sequence-based contact predictions

Structure

DOI

2011

Improving the physical realism and structural accuracy of protein models by a two-step atomic-level energy minimization.

Biophysical Journal

DOI

2011

Atomic-level protein structure refinement using fragment guided molecular dynamics conformation sampling

Structure

DOI

2010

新型Tet-On系统大鼠GDNF和TH双基因的慢病毒载体的构建与表达

《中国药理学通报》

2010

过表达Nanog基因的小鼠骨髓间质干细胞对NF-κB表达的影响

《生物工程学报》

2010

A three‐dimensional model of the U1 small nuclear ribonucleoprotein particle

DOI

2010

How significant is a protein structure similarity with TM-score = 0.5?

Bioinform.

DOI

2010

Composite Approaches to Protein Tertiary Structure Prediction: A Case-Study by I-Tasser

DOI

2010

A Novel Side-Chain Orientation Dependent Potential Derived from Random-Walk Reference State for Protein Fold Selection and Structure Prediction

PLoS ONE

DOI

2010

MVP-Fit: A Convenient Tool for Flexible Fitting of Protein Domain Structures with Cryo-Electron Microscopy Density Map

2010

Recognizing Protein Substructure Similarity Using Segmental Threading

Structure

DOI

2010

GPCRRD: G protein-coupled receptor spatial restraint database for 3D structure modeling and function annotation

Bioinform.

DOI

2009

增强型绿色荧光蛋白和大鼠血管生长素-1基因共表达的重组慢病毒体外转染大鼠骨髓间充质干细胞

《空军军医大学学报》

2009

EGFP和大鼠GDNF基因共表达的慢病毒载体构建及转染大鼠骨髓间充质干细胞

《神经解剖学杂志》

2009

MM-align: a quick algorithm for aligning multiple-chain protein complex structures using iterative dynamic programming

Nucleic Acids Research

DOI

2009

Protein Structure Prediction: Is It Useful?

Current Opinion in Structural Biology

DOI

2009

PROTEIN STRUCTURE PREDICTION II

2009

Revisiting the Plasmodium falciparum RIFIN family: from comparative genomics to 3D-model prediction

BMC Genomics

DOI

2009

I-TASSER: Fully automated protein structure prediction in CASP8

Proteins: Structure, Function, and Bioinformatics

DOI

2009

Generating Triangulated Macromolecular Surfaces by Euclidean Distance Transform

PLoS ONE

DOI

2009

HAAD: A Quick Algorithm for Accurate Prediction of Hydrogen Atoms in Protein Structures

PLoS ONE

DOI

2009

REMO: A New Protocol to Refine Full Atomic Protein Models from C-alpha Traces by Optimizing Hydrogen-Bonding Networks

Proteins: Structure, Function, and Bioinformatics

DOI

2008

149位丝氨酸在CDC25B诱导小鼠卵母细胞减数分裂中的功能

《细胞与分子免疫学杂志》

2008

Progress and challenges in protein structure prediction.

Current Opinion in Structural Biology

DOI

2008

ANGLOR: A Composite Machine-Learning Algorithm for Protein Backbone Torsion Angle Prediction

PLoS ONE

DOI

2008

MUSTER: Improving protein sequence profile–profile alignments by using multiple sources of structure information

Proteins: Structure, Function, and Bioinformatics

DOI

2007

LOMETS: A local meta-threading-server for protein structure prediction

Nucleic Acids Research

DOI

2007

Template‐based modeling and free modeling by I‐TASSER in CASP7

Proteins: Structure, Function, and Bioinformatics

DOI

2007

Monte Carlo refinement of rigid‐body protein docking structures with backbone displacement and side‐chain optimization

Protein Science

DOI

2007

Identification of near‐native structures by clustering protein docking conformations

Proteins: Structure, Function, and Bioinformatics

DOI

2007

Scoring function for automated assessment of protein structure template quality

DOI

2006

On the origin and highly likely completeness of single-domain protein structures.

Proceedings of the National Academy of Sciences of the United States of America

DOI

2006

Benchmarking of dimeric threading and structure refinement

Proteins: Structure, Function, and Bioinformatics

DOI

2006

Correction: Structure Modeling of All Identified G Protein–Coupled Receptors in the Human Genome

PLoS Comput. Biol.

DOI

2006

TASSER-Lite: an automated tool for protein comparative modeling.

Biophysical Journal

DOI

2006

TASSER‐based refinement of NMR structures

Proteins: Structure, Function, and Bioinformatics

DOI

2006

Structure Modeling of All Identified G Protein–Coupled Receptors in the Human Genome

PLoS Comput. Biol.

DOI

2005

TM-align: a protein structure alignment algorithm based on the TM-score

Nucleic Acids Research

DOI

2005

The protein structure prediction problem could be solved using the current PDB library.

Proceedings of the National Academy of Sciences of the United States of America

DOI

2005

TASSER: An automated method for the prediction of protein tertiary structures in CASP6

Proteins: Structure, Function, and Bioinformatics

DOI

2004

Automated structure prediction of weakly homologous proteins on a genomic scale.

Proceedings of the National Academy of Sciences of the United States of America

DOI

2004

Application of sparse NMR restraints to large-scale protein structure prediction.

Biophysical Journal

DOI

2004

Tertiary structure predictions on a comprehensive benchmark of medium to large size proteins.

Biophysical Journal

DOI

2002

Ab initio protein structure prediction on a genomic scale: Application to the Mycoplasma genitalium genome

Proceedings of the National Academy of Sciences of the United States of America

DOI

2024

肿瘤微环境中肿瘤坏死因子α维持胶质瘤干细胞自我更新的机制研究

《中国解剖学会2024年年会论文文摘汇编》

DOI

2015

TGF-β1对乳腺癌干细胞特性的影响

《全国肿瘤流行病学和肿瘤病因学学术会议论文集》

2013

MicroRNA-146a介导肝癌细胞侵袭转移的机制研究

《细胞—生命的基础——中国细胞生物学学会2013年全国学术大会·武汉》

2012

FOXO1在肝脏胰岛素抵抗相关的慢性炎症中的作用

《生命的分子机器及其调控网络——2012年全国生物化学与分子生物学学术大会》

2011

毛囊干细胞靶向表达Sox9转基因小鼠模型的制备

《中国的遗传学研究——遗传学进步推动中国西部经济与社会发展——2011年中国遗传学会大会论文摘要汇编》

2011

骨斑点症一家系中LEMD3基因的新突变及功能分析

《中国的遗传学研究——遗传学进步推动中国西部经济与社会发展——2011年中国遗传学会大会》

2009

FOXO1基因调节胰岛β细胞中增殖凋亡相关靶基因的检测及鉴定

《重庆市生物化学与分子生物学学术会议论文摘要汇编》

2009

地塞米松在HepG2细胞中通过上调FoxO1诱导IL1β表达

《重庆市生物化学与分子生物学学术会议》

2009

毛囊靶向表达SOX9转基因小鼠模型的制备

《第八次全国医学遗传学学术会议(中华医学会2009年医学遗传学年会)论文摘要汇编》

2009

MCP-15'侧翼启动子区域的功能分析及与FoxO1的关系研究

《重庆市生物化学与分子生物学学术会议》

2024

Functional photoacoustic noninvasive Doppler angiography in humans

arXiv preprint

2022

Transcranial photoacoustic computed tomography of human brain function

arXiv preprint

2022

Ultra-stable radioactive microspheres enabled by radiation-induced graft polymerization for imaging-guided intra-arterial brachytherapy

Research Square

DOI

2021

A Pure NanoICG-Based Homogeneous Lipiodol Formulation: Toward Precise Surgical Navigation of Hepatocellular Carcinoma After Long-Term Transcatheter Arterial Embolization

Research Square

DOI