百晓学者学者目录

张思

副教授、教授、讲师，复旦大学

精选作品

期刊论文

2026

A环7-取代白杨素衍生物的合成及其抗癌活性研究

游波，陈洪飞，彭雅玲，张思，郑兴，姚旭，郑自通

《天津药学》

DOI

2026

Author Correction: Low-protein diet enhances antitumor immunity in pancreatic cancer through microbiota-derived UDP-galactose.

Yue-Ying Chen, Fulin Nian, Sheng-Di Wu, Tianli Yuan, Yi-Fan Ma, Junyang Cao, Yu-Xiao Zhang, Wenfeng Liu, Wen-Qing Tang, Danying Zhang, Zi Li, Wei Lu, Fengwanni Wang, Xiu-Long Xia, Zhan-Ju Liu, Si Zhang, Xi-Zhong Shen, Xiaoming Hu, Ling Dong

Nature Cancer

DOI

2026

Low-protein diet enhances antitumor immunity in pancreatic cancer through microbiota-derived UDP-galactose.

Yue-Ying Chen, Fulin Nian, Sheng-Di Wu, Tianli Yuan, Yi-Fan Ma, Junyang Cao, Yu-Xiao Zhang, Wenfeng Liu, Wen-Qing Tang, Danying Zhang, Zi Li, Wei Lu, Fengwanni Wang, Xiu-Long Xia, Zhan-Ju Liu, Si Zhang, Xi-Zhong Shen, Xiaoming Hu, Ling Dong

Nature Cancer

DOI

2025

海洋放线菌Actinoalloteichus cyanogriseus LHW52806的活性次级代谢产物研究

林昕历，张思，李蕾，张帅帅，张云，林厚文，张翠仙，王淑萍

《中国抗生素杂志》

2025

6-aminonicotinamide, a G6PD inhibitor, mitigates CAPS1 reduction mediated HCC metastasis via ERK and GSK3β signals

Xia-Hui Lin, Yingying Xu, En-Cheng Bai, Yiran Deng, Wei Zhang, R. Xue, Si Zhang, Li Zhang, Wen-Qing Tang, Ling Dong, She Chen

Neoplasia

DOI

2025

Corrigendum to “6-Aminonicotinamide, a G6PD inhibitor, mitigates CAPS1 reduction mediated HCC metastasis via ERK and GSK3β signals” [Neoplasia volume 70 (2025) 101239]

Xia-Hui Lin, Yingying Xu, En-Cheng Bai, Yiran Deng, Wei Zhang, R. Xue, Si Zhang, Li Zhang, Wen-Qing Tang, Ling Dong, She Chen

Neoplasia

DOI

2025

Rewiring PD-1/PD-L1 combination therapy via glyco-immune targeting of galectins: Toward clinical translation

Xiangyu Huang, Si Zhang, Jiale Li, She Chen

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

DOI

2025

Cancer-associated fibroblast miR-148a-5p/CALD1/collagen VI pathway promotes proliferation in Helicobacter pylori-positive gastric cancer

Qiuyu Jiang, Hao Zhang, Yu Cai, Fansheng Meng, Huibin Wu, Wenfeng Liu, Feng Zhang, He Chen, Zhixue Chen, Xizhong Shen, Ling Dong, Si Zhang, Ruyi Xue

Cellular Oncology

DOI

2025

ALDH2 rs671 variant enhances platelet activation and thrombosis by disrupting mitochondrial complex I assembly

Haoxuan Zhong, Maieryemu Waresi, Zhiyong Qi, Luning Zhou, Wei Zhang, Xiaolei Sun, Liping Han, Zhihan Chen, Wenxuan Zhou, Peng Zhang, Huajie Xu, Si Zhang, Hongyi Wu, Aijun Sun, Junbo Ge

Cardiovascular Research

DOI

2025

USP25-mediated talin-1 stabilization in platelets: a novel mechanism of hyperreactivity and thrombosis risk during aging

Xuemei Jia, Shuoyi Jiang, Hong Cheng, Zhicheng Wang, Zhihan Chen, Weiguo Dong, Haoxuan Zhong, Qi Zhang, Xianmin Song, Si Zhang, Rong Mu Xia

Blood

DOI

2025

Endoplasmic Reticulum Stress‐Induced triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Downregulation Exacerbates Platelet Activation and Myocardial Infarction in Patients With Coronary Artery Disease

Xiaowen Wu, Guanxing Pan, Lin Chang, Qian Liu, Yangyang Liu, Wei Zhang, Yifan Guo, Ge Zhang, Haoxuan Zhong, Zhiyong Qi, Jianjun Zhang, Ruyi Xue, She Chen, Hu Hu, Jianzeng Dong, Si Zhang, Zhongren Ding

Journal of the American Heart Association

DOI

2025

Ultra-high gene transfection efficiency in suspension cells mediated by highly branched-linear poly(β-amino ester)s

Chenfei Wang, Tao Bo, Chen Wu, Feifei Wang, Nandi Wang, Rui Guo, Yitong Zhao, Chaolan Pan, Yuhui Zhang, Dingjin Yao, Xing Wang Zhou, Si Zhang, Ming Zeng, Minghui Li, Dezhong Zhou

Journal of Controlled Release

DOI

2025

PM2.5 promotes platelet activation and thrombosis via ROS/MAPKs pathway-mediated mitochondrial dysfunction

Yuquan Xie, Dongxia Fan, Biao Wu, Jianshu Guo, Ge Wang, Yu Lu, Chihang Zhang, Chihang Zhang, Jinzhuo Zhao, Si Zhang

Environmental Research

DOI

2024

Activation of NOD1 on tumor-associated macrophages augments CD8+ T cell–mediated antitumor immunity in hepatocellular carcinoma

Feng Zhang, Qiu-Yu Jiang, Jialiang Cai, Fan-Sheng Meng, Wen-Qing Tang, Zhiyong Liu, Xia-Hui Lin, Wenfeng Liu, Yi Zhou, Xi-Zhong Shen, R. Xue, Ling Dong, Si Zhang

Science Advances

DOI

2024

Inhibiting PLA2G7 reverses the immunosuppressive function of intratumoral macrophages and augments immunotherapy response in hepatocellular carcinoma

Feng Zhang, Wenfeng Liu, Fan-Sheng Meng, Qiu-Yu Jiang, Wen-Qing Tang, Zhiyong Liu, Xia-Hui Lin, R. Xue, Si Zhang, Ling Dong

Journal for ImmunoTherapy of Cancer

DOI

2024

Increased PRP19 in Hepatocyte Impedes B Cell Function to Promote Hepatocarcinogenesis

Zhiyong Liu, Xia-Hui Lin, Danying Zhang, Dezhen Guo, Wen-Qing Tang, Xiangnan Yu, Feng Zhang, Si Zhang, R. Xue, Xi-Zhong Shen, Ling Dong

Advancement of science

DOI

2024

Endoplasmic Reticulum-Targeting Highly Branched Poly(β-amino ester)s for Skin Gene Delivery

Chenfei Wang, Wei He, Rui Feng Guo, Chaolan Pan, Haiyang Yong, Tao Bo, Yitong Zhao, Zhili Li, Feifei Wang, Weiyi Xu, Dingjin Yao, Si Zhang, Ming Li, Dezhong Zhou

ACS Materials Letters

DOI

2024

GSDME-mediated pyroptosis contributes to chemotherapy-induced platelet hyperactivity and thrombotic potential

Ruyi Xue, Min� Li, Ge Zhang, Wei Zhang, Liping Han, Tao Bo, Haoxuan Zhong, Dingjin Yao, Yiran Deng, She Chen, Si Zhang

Blood

DOI

2024

Absence of platelet overactivation and thrombosis formation among patients with coronary atherosclerosis disease after vaccination against SARS-CoV-2

Huajie Xu, Xin Zhao, Peng Zhang, Yunjie Zhang, Qi Zhou, Huibin Wu, Bing Fan, Si Zhang, Hongyi Wu

Heliyon

DOI

2024

Double-stranded DNA enhances platelet activation, thrombosis, and myocardial injury via cyclic GMP-AMP synthase

Wei Yan Zhang, Yan Zhang, Liping Han, Tao Bo, Zhiyong Qi, Haoxuan Zhong, Huajie Xu, Liang Hu, She Chen, Si Zhang

Cardiovascular Research

DOI

2024

Liver function abnormality on admission predicts long COVID syndrome in digestive system

Huibin Wu, Yunjie Zhang, Wenqing Tang, Minzhi Lv, Zhixue Chen, Fansheng Meng, Yitong Zhao, Huajie Xu, Yuxin Dai, Jindan Xue, Jingya Wang, Ling Dong, Dejun Wu, Si Zhang, Ruyi Xue

Heliyon

DOI

2024

ADAM17 variant causes hair loss via ubiquitin ligase TRIM47–mediated degradation

Xiaoxiao Wang, Chaolan Pan, Luyao Zheng, Jianbo Wang, Quan Zou, Peiyi Sun, Kaili Zhou, Anqi Zhao, Qiaoyu Cao, Wei He, Yumeng Wang, Ruhong Cheng, Zhirong Yao, Si Zhang, Hui Zhang, Ming Li

JCI Insight

DOI

2024

OSBPL2 compound heterozygous variants cause dyschromatosis, ichthyosis, deafness and atopic disease syndrome

Yumeng Wang, Anqi Zhao, Naihui Zhou, Xiaoxiao Wang, Chaolan Pan, Shengru Zhou, Haisheng Huang, Yijun Yang, Jianqiu Yang, Yifan Yang, Jingwen Zhang, Fuying Chen, Qiaoyu Cao, Jingjun Zhao, Si Zhang, Ming Li, Min Li

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

DOI

2024

Superior COL7A1 and TGM1 gene expression in difficult-to-transfect skin cell mediated by highly branched poly(β-amino esters) through stepwise fractionation

Chaolan Pan, Chenfei Wang, Yitong Zhao, Tao Bo, Liping Han, Dingjin Yao, Yumeng Wang, Xiaoxiao Wang, Linjing Shi, Anqi Zhao, Qiaoyu Cao, Fuying Chen, Wei He, Ying Ye, Si Zhang, Ming Li

Journal of Controlled Release

DOI

2024

Efficient gene delivery by multifunctional star poly (β-amino ester)s into difficult-to-transfect macrophages for M1 polarization

Tao Bo, Chenfei Wang, Dingjin Yao, Qiuyu Jiang, Yitong Zhao, Feifei Wang, Wei He, Weiyi Xu, Hao Zhou, Ming Li, Si Zhang, Ruyi Xue

Journal of Controlled Release

DOI

2024

Recent progress of non-linear topological structure polymers: synthesis, and gene delivery

Chenfei Wang, Wei He, Feifei Wang, Haiyang Yong, Tao Bo, Dingjin Yao, Yitong Zhao, Chaolan Pan, Qiaoyu Cao, Si Zhang, Ming Li

Journal of Nanobiotechnology

DOI

2023

CD36-BATF2\MYB Axis Predicts Anti-PD-1 Immunotherapy Response in Gastric Cancer

Qiu-Yu Jiang, Zhi-Xue Chen, Fansheng Meng, Hao Zhang, He-Hui Chen, Jindan Xue, Xi-Zhong Shen, Tianshu Liu, Ling Dong, Si Zhang, R. Xue

International Journal on Biological Sciences

DOI

2023

Eleven metabolism‑related genes composed of Stard5 predict prognosis and contribute to EMT phenotype in HCC

Dong-ping Li, Xia-Hui Lin, Jiale Li, Xinyi Liu, Feng Zhang, Wen-Qing Tang, Si Zhang, Ling Dong, R. Xue

Cancer Cell International

DOI

2023

Inactivated vaccines reduce the risk of liver function abnormality in NAFLD patients with COVID-19: a multi-center retrospective study

Zhixue Chen, Wenqing Tang, Nana Feng, Minzhi Lv, Fansheng Meng, Huibin Wu, Yitong Zhao, Huajie Xu, Yuxin Dai, Jindan Xue, Jingya Wang, Anjun Xu, Beilin Zhang, De-Jie Chu, Yuqin Li, Dejun Wu, Ling Dong, Si Zhang, Ruyi Xue

EBioMedicine

DOI

2023

Superior TRAIL gene expression and cancer cell apoptosis mediated by highly branched-linear poly(β-amino ester)s

Yitong Zhao, Tao Bo, Chenfei Wang, Dingjin Yao, Chaolan Pan, Weiyi Xu, Hao Zhou, Ming Li, Si Zhang

Journal of Nanobiotechnology

DOI

2023

Comprehensive Analysis of Prognostic Value and Immune Infiltration of Src Family Kinases in Hepatocellular Carcinoma

Dingjin Yao, Yiran Deng, Si Zhang, Limiao Liang, Li Zhang, Shu‐Qiang Weng, She Chen

Frontiers in Bioscience-Landmark

DOI

2023

MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia

Fanfan Li, Yixiang Han, Rongrong Chen, Yinyan Jiang, Cheng Chen, Xiaofang Wang, Jifan Zhou, Qingqing Xu, Songfu Jiang, Si Zhang, Si Zhang, Kang Yu, Shenghui Zhang, Shenghui Zhang

Journal of Translational Medicine

DOI

2023

Six immune-related promising biomarkers may promote hepatocellular carcinoma prognosis: a bioinformatics analysis and experimental validation

Xiahui Lin, Dongping Li, Zhiyong Liu, Si Zhang, Wenqing Tang, Rongxin Chen, Shu‐Qiang Weng, Yujen Tseng, Ruyi Xue, Ling Dong

Cancer Cell International

DOI

2023

Editorial: Tumor metabolism: From molecular mechanisms to clinical application

Chunming Cheng, Si Zhang, Dongyin Guan, Yi Wang, Nidhi Jyotsana

Frontiers in Cell and Developmental Biology

DOI

2023

Inactivated whole-virion SARS-CoV-2 vaccines and long-term clinical outcomes in patients with coronary atherosclerosis disease in China: a prospective cohort study

Huajie Xu, Jiaojiao Zheng, Xin Zhao, Qi Zhou, Bing Fan, Hongyi Wu, Si Zhang, Junbo Ge

Cardiovascular Research

DOI

2022

circRanGAP1/miR-27b-3p/NRAS Axis may promote the progression of hepatocellular Carcinoma

Xia-Hui Lin, Zhi-Yong Liu, Dan-Ying Zhang, Si Zhang, Wendong Tang, Dong-ping Li, Feng Zhang, Rong Chen, S. Weng, R. Xue, Ling Dong

Experimental Hematology & Oncology

DOI

2022

Immunoglobulin superfamily 9 (IGSF9) is trans-activated by p53, inhibits breast cancer metastasis via FAK

Yaohua Li, Yiran Deng, Yannan Zhao, Wei Zhang, Si Zhang, Li Zhang, Biyun Wang, Yingying Xu, She Chen

Oncogene

DOI

2022

Proscillaridin A induces mitochondrial damage and autophagy in pancreatic cancer and reduces the stability of SMAD4 in Panc-1 cells

Jia Hou, Ning Kang, Nannan Liu, Dan Tan, Si Zhang, Jing Liu, Youhua Xie

Annals of Translational Medicine

DOI

2022

Protein tyrosine phosphatase PTPN22 negatively modulates platelet function and thrombus formation

Xiamin Wang, Guangyu Wei, Yangyang Ding, Xiang Gui, Huan Tong, Xiao‐Qi Xu, Sixuan Zhang, Zengtian Sun, Wen Ju, Yue Li, Ruosi Yao, Qingyu Wu, Zhihao Lu, Chunling Fu, Zhenyu Li, Si Zhang, Elizabeth E. Gardiner, Robert K. Andrews, Hu Hu, Lingyu Zeng, Kailin Xu, Jianlin Qiao

Blood

DOI

2022

Future therapies for pancreatic carcinoma: Insights into cancer precision medicine

Qiuyu Jiang, Zhi-Xue Chen, Si Zhang, Ruyi Xue

World Journal of Gastroenterology

DOI

2022

S1P defects cause a new entity of cataract, alopecia, oral mucosal disorder, and psoriasis‐like syndrome

Fuying Chen, Cheng Ni, Xiao-Xiao Wang, Ruhong Cheng, Chaolan Pan, Yumeng Wang, Jianying Liang, Jia Zhang, Jinke Cheng, Yue Eugene Chin, Yi Zhou, Zhen Wang, Yiran Guo, She Chen, Stephanie Htun, Erin F. D. Mathes, Alejandra G. de Alba Campomanes, Anne Michele Slavotinek, Si Zhang, Ming Li, Zhirong Yao

EMBO Molecular Medicine

DOI

2022

Galectin 3 enhances platelet aggregation and thrombosis via Dectin-1 activation: a translational study

Yufei Chen, Wanrong Fu, Yunbo Zheng, Jing Yang, Yangyang Liu, Zhiyong Qi, Meiling Wu, Zhichao Fan, Kanhua Yin, Yunfeng Chen, Wen Gao, Zhongren Ding, Jianzeng Dong, Qi Li, Si Zhang, Liang Hu

European Heart Journal

DOI

2022

A plasma SNORD33 signature predicts platinum benefit in metastatic triple-negative breast cancer patients

Biyun Wang, Yannan Zhao, Yi Li, Yingying Xu, Yun Chen, Qiuyu Jiang, Dingjin Yao, Li Zhang, Xichun Hu, Chaowei Fu, Si Zhang, She Chen

Molecular Cancer

DOI

2022

Editorial: Platelets in Disease: From Biomarkers Discovery to Therapeutic Targets

Fan Zhao, Si Zhang, Shenghui Zhang, Shenghui Zhang, Shenghui Zhang

Frontiers in Pharmacology

DOI

2021

短链脂肪酸在炎症性肠病中的免疫调节作用

陈玉琼，顾天宇，张思，朱雪婷，雷爱华

《现代免疫学》

2021

Activation of Platelet NLRP3 Inflammasome in Crohn’s Disease

Ge Zhang, He-Hui Chen, Yi-Fan Guo, Wei Zhang, Qiu-Yu Jiang, Si Zhang, Li-Ping Han, She Chen, R. Xue

Frontiers in Pharmacology

DOI

2021

Hepatic NOD2 promotes hepatocarcinogenesis via a RIP2-mediated proinflammatory response and a novel nuclear autophagy-mediated DNA damage mechanism

Yi Zhou, Lian-Gao Hu, Wen-Qing Tang, Dong-ping Li, Lijie Ma, Hong-Chun Liu, Shun-Cai Zhang, Xiao-Jie Zhang, Ling Dong, Xi-Zhong Shen, She Chen, R. Xue, Si Zhang

Journal of Hematology & Oncology

DOI

2021

Identification of prognostic miRNA-mRNA regulatory network in the progression of HCV-associated cirrhosis to hepatocellular carcinoma

Li-Ping Han, Xuemei Jia, Weinire Abuduwaili, Dong-ping Li, He-Hui Chen, Qiuyu Jiang, She Chen, Si Zhang, Rong Xia, R. Xue

Translational Cancer Research

DOI

2021

The role of Sphingomyelin synthase 2 (SMS2) in platelet activation and its clinical significance

Yi-Fan Guo, Lin Chang, Ge Zhang, Zhanyan Gao, Hao Lin, Yu-Ting Zhang, Liang Hu, She Chen, Bing Fan, Si Zhang, R. Xue

Thrombosis Journal

DOI

2021

Gut Microbiota and Immune Checkpoint Inhibitors-Based Immunotherapy.

M. Tian, Si Zhang, Yu-Jen Tseng, Xi-Zhong Shen, Ling Dong, R. Xue

Anti-Cancer Agents in Medicinal Chemistry

DOI

2021

Comprehensive Characterization of Immunological Profiles and Clinical Significance in Hepatocellular Carcinoma

P. Tao, Liang Hong, Wen-Qing Tang, Qun Lu, Yanrong Zhao, Si Zhang, Lijie Ma, R. Xue

Frontiers in Oncology

DOI

2021

Gut microbiota-mediated immunomodulation in tumor

Xinyi Liu, Yanjie Chen, Si Zhang, Ling Dong

Journal of experimental & clinical cancer research : CR

DOI

2021

The long non-coding RNA DKFZp434J0226 regulates the alternative splicing process through phosphorylation of SF3B6 in PDAC

Jinglei Li, Han-Xing Tong, Dong-ping Li, Qiuyu Jiang, Yong Zhang, Wen-Qing Tang, Dayong Jin, She Chen, Xinyu Qin, Si Zhang, R. Xue

Molecular Medicine

DOI

2021

NOD2-mediated P2Y12 upregulation increases platelet activation and thrombosis in sepsis

Haoxuan Zhong, Maieryemu Waresi, Wei Zhang, Liping Han, Yikai Zhao, Yufei Chen, Peng Zhou, Lin Chang, Guanxing Pan, Bangwei Wu, Jian Li, Si Zhang, Haiming Shi, Xinping Luo, Wen Gao, Zhiyong Qi, Zhongren Ding

Biochemical Pharmacology

DOI

2021

Loss of polarity protein Par3 is mediated by transcription factor Sp1 in breast cancer

Yannan Zhao, Dingjin Yao, Yi Li, Si Zhang, Zhonghua Tao, Li Zhang, Xichun Hu, Biyun Wang, She Chen

Biochemical and Biophysical Research Communications

DOI

2021

Loss of polarity protein Par3, via transcription factor Snail, promotes bladder cancer metastasis

Shenyi Wang, Jinming Cai, Si Zhang, Mingwei Dong, Li Zhang, Yingying Xu, Bing Shen, She Chen

Cancer Science

DOI

2021

MRCKβ links Dasm1 to actin rearrangements to promote dendrite development

Xiao-Xiao Wang, Si Zhang, Ping-Ping Dong, Yaohua Li, Li Zhang, Song‐Hai Shi, Zhiqiang Yu, She Chen

Journal of Biological Chemistry

DOI

2020

Clinicopathological and prognostic implications of vessels encapsulate tumor clusters with PD-L1 in intrahepatic cholangiocarcinoma patients

P. Tao, Lijie Ma, R. Xue, Haijie Wang, Si Zhang

Translational Cancer Research

DOI

2020

CD86+/CD206+ tumor-associated macrophages predict prognosis of patients with intrahepatic cholangiocarcinoma

Da-Long Sun, Tiancheng Luo, P. Dong, Ning-ping Zhang, Jing Chen, Shun-Cai Zhang, Longzi Liu, Ling Dong, Si Zhang

PeerJ

DOI

2020

Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma.

P. Dong, Xiaoxiao Wang, Longzi Liu, Wen-Qing Tang, Lijie Ma, Wen-Jiao Zeng, Shaoyang Sun, Li Zhang, Ning-Xia Zhang, Xi-Zhong Shen, H. Janssen, Ling Dong, Si Zhang, She Chen

Journal of Hepatology

DOI

2020

GSK669, a NOD2 receptor antagonist, inhibits thrombosis and oxidative stress via targeting platelet GPVI

Guanxing Pan, Lin Chang, Jianjun Zhang, Yangyang Liu, Liang Hu, Si Zhang, Jian Zhang, Jianlin Qiao, Žiga Jakopin, Hu Hu, Jianzeng Dong, Zhongren Ding

Biochemical Pharmacology

DOI

2020

Expression and Clinical Prognostic Value of Platelet NLRP3 in Acute Coronary Syndrome

Huitong Peng, Hongyi Wu, Ge Zhang, Wei Zhang, Yifan Guo, Lin Chang, She Chen, Ruyi Xue, Si Zhang

International Journal of General Medicine

DOI

2020

SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19

Si Zhang, Si Zhang, Yangyang Liu, Xiaofang Wang, Haishan Li, Haishan Li, Yuyan Wang, Mengduan Liu, Xiaoyan Zhao, Youhua Xie, Yan Yang, Shenghui Zhang, Shenghui Zhang, Zhenghong Yuan, Zhongren Ding, Zhenghong Yuan, Zhongren Ding, Yi Zhang, Liang Hu

Journal of Hematology & Oncology

DOI

2020

PAK Membrane Translocation and Phosphorylation Regulate Platelet Aggregation Downstream of Gi and G12/13 Pathways

Jianjun Zhang, Yan Zhang, Shuang Zheng, Yangyang Liu, Lin Chang, Guanxing Pan, Liang Hu, Si Zhang, Junling Liu, Soochong Kim, Jianzeng Dong, Zhongren Ding

Thrombosis and Haemostasis

DOI

2019

Exosomes isolated from CAPS1-overexpressing colorectal cancer cells promote cell migration

Bingrui Wu, Da-Long Sun, Lijie Ma, Yiran Deng, Si Zhang, Ling Dong, She Chen

Oncology Report

DOI

2019

CAPS1 promotes colorectal cancer metastasis via Snail mediated epithelial mesenchymal transformation

Guang-Xi Zhao, Yingying Xu, S. Weng, Si Zhang, Ying Chen, Xi-Zhong Shen, Ling Dong, She Chen

Oncogene

DOI

2019

M2‐polarized tumor‐associated macrophages promote epithelial‐mesenchymal transition via activation of the AKT3/PRAS40 signaling pathway in intrahepatic cholangiocarcinoma

Da-Long Sun, Tian-Cheng Luo, P. Dong, Ning-ping Zhang, Jing Chen, Shun-Cai Zhang, Ling Dong, H. Janssen, Si Zhang

Journal of Cellular Biochemistry

DOI

2019

TREM2 acts as a tumor suppressor in hepatocellular carcinoma by targeting the PI3K/Akt/β-catenin pathway

Wen-Qing Tang, B. Lv, Bi-Wei Yang, Yu-Kai Chen, Feifei Yuan, Lijie Ma, She Chen, Si Zhang, J. Xia

Oncogenesis

DOI

2019

Autophagy promotes aortic adventitial fibrosis via the IL-6/Jak1 signaling pathway in Takayasu's arteritis

Rongyi Chen, Ying Jie Sun, Xiaomeng Cui, Zongfei Ji, Xiufang Kong, Sifan Wu, Qingrong Huang, Xiaoming Dai, Si Zhang, Lili Ma, Lindi Jiang

Journal of Autoimmunity

DOI

2018

异源物核受体激活机制在调控药物代谢中的研究现状

徐艳娇，张思，鲁憬莉，张程亮，刘东

《中国临床药理学杂志》

2018

Dynamic network biomarker indicates pulmonary metastasis at the tipping point of hepatocellular carcinoma

Bi-Wei Yang, Mei-Yi Li, Wen-Qing Tang, Wei-Xin Liu, Si Zhang, Luo-Nan Chen, J. Xia

Nature Communications

DOI

2018

Benzene induces haematotoxicity by promoting deacetylation and autophagy

Shanhu Qian, Yi-Xiang Han, Yifen Shi, Wanling Xu, Yiyi Zhu, Song-Fu Jiang, Yi Chen, Zhi-Jie Yu, Si Zhang, Yi-Ping Yang, K. Yu, Sheng-Hui Zhang

Journal of Cellular and Molecular Medicine

DOI

2018

Cholestasis-induced bile acid elevates estrogen level via farnesoid X receptor–mediated suppression of the estrogen sulfotransferase SULT1E1

Xijun Liu, R. Xue, Caiting Yang, Jian-Xin Gu, She Chen, Si Zhang

Journal of Biological Chemistry

DOI

2018

FXR Acts as a Metastasis Suppressor in Intrahepatic Cholangiocarcinoma by Inhibiting IL-6-Induced Epithelial-Mesenchymal Transition

B. Lv, Lijie Ma, Wen-Qing Tang, Pei-Xin Huang, Bi-Wei Yang, Ling-Xia Wang, She Chen, Q. Gao, Si Zhang, J. Xia

Cellular Physiology and Biochemistry

DOI

2018

Smurf2, an E3 ubiquitin ligase, interacts with PDE4B and attenuates liver fibrosis through miR-132 mediated CTGF inhibition.

Yu Cai, Guanqun Huang, Lijie Ma, Ling Dong, She Chen, Xi-Zhong Shen, Shun-Cai Zhang, R. Xue, Deqiang Sun, Si Zhang

Biochimica et biophysica acta. Molecular cell research

DOI

2018

Pro-fibrotic effect of IL-6 via aortic adventitial fibroblasts indicates IL-6 as a treatment target in Takayasu arteritis.

Xiufang Kong, Lan Ma, Zongfei Ji, Zhihui Dong, Zhigang Zhang, Jun Hou, Si Zhang, Lingying Ma, Lindi Jiang

PubMed

2018

Response by Hu et al to Letters Regarding Article, “Platelets Express Activated P2Y 12 Receptor in Patients With Diabetes Mellitus”

Liang Hu, Zhiyong Qi, Si Zhang, Xinping Luo, Satya P. Kunapuli, Hongying Ye, Zhongren Ding

Circulation

DOI

2017

环巴胺对子宫内膜癌HEC-1A细胞存活与凋亡的影响

张萍萍，李雪，刘元林，张思，周向东，童英，张毅

《军事医学》

2017

Platelets Express Activated P2Y 12 Receptor in Patients With Diabetes Mellitus

Liang Hu, Lin Chang, Yan Zhang, Lili Zhai, Shenghui Zhang, Zhiyong Qi, Hongmei Yan, Yan Yan, Xinping Luo, Si Zhang, Yiping Wang, Satya P. Kunapuli, Hongying Ye, Zhongren Ding

Circulation

DOI

2016

顺铂通过抑制转移抑制基因1-细胞外信号调节激酶及丝氨酸/苏氨酸激酶激活抑制HeLa细胞增殖

张思，刘元林，李雪，周向东，赵岳，张萍萍，童英，张毅

《中国药理学与毒理学杂志》

2016

真核翻译起始因子4G与肿瘤

张思，黄楠，潘霞，臧婧蕾，管馨馨，张建华，刘柳成，雷小勇

《生理学报》

2016

宫颈癌中MTSS1基因与Shh信号通路的关系研究

张思，李雪，刘元林，周向东，张萍萍，童英，张毅

《军事医学》

2016

宫颈癌中MTSS1基因的表达及其临床意义

张思，刘元林，周向东，赵岳，童英，张毅

《军事医学》

2016

CAPS1 Negatively Regulates Hepatocellular Carcinoma Development through Alteration of Exocytosis-Associated Tumor Microenvironment

R. Xue, Wen-Qing Tang, P. Dong, S. Weng, Lijie Ma, She Chen, Tao-Tao Liu, Xi-Zhong Shen, Xiao-Wu Huang, Si Zhang, Ling Dong

International Journal of Molecular Sciences

DOI

2016

CD86+/CD206+, Diametrically Polarized Tumor-Associated Macrophages, Predict Hepatocellular Carcinoma Patient Prognosis

P. Dong, Lijie Ma, Longzi Liu, Guangxi Zhao, Si Zhang, Ling Dong, R. Xue, She Chen

International Journal of Molecular Sciences

DOI

2016

Overexpression of protein O-fucosyltransferase 1 accelerates hepatocellular carcinoma progression via the Notch signaling pathway

Lijie Ma, Pingping Dong, Longzi Liu, Qiang Gao, Meng Duan, Si Zhang, She Chen, Ruyi Xue, Xiaoying Wang

Biochemical and Biophysical Research Communications

DOI

2015

甲氨蝶呤对大鼠脊髓挫伤急性期氧化损伤相关蛋白的影响

张思，顾兵，李华南，王烁宇，张水印

《中国临床药理学与治疗学》

2015

辛二酰苯胺异羟肟酸联合紫杉醇对卵巢癌细胞OC3杀伤与自噬的影响

赵岳，刘元林，刘朝晖，张思，童英，张毅

《军事医学》

2015

急性脊髓损伤后的炎症反应及其抗炎治疗

王涛丽，顾兵，李华南，张国福，张思

《中国药理学通报》

2015

辛二酰苯胺异羟肟酸诱导人卵巢癌细胞OC3自噬作用

赵岳，刘朝晖，张思，刘元林，周向东，王洋，童英，张毅

《中国药理学与毒理学杂志》

2015

Sa1842 Trem2 Suppresses Tumorigenesis and Metastasis by Targeting the PI3K/Akt/GSK3β/β-Catenin Pathway in Hepatocellular Carcinoma

Wen-Qing Tang, Bi-Wei Yang, Zhi-Ying Zhao, Hui Tian, Xiao-Jing Xu, Pei-Xin Huang, Si Zhang, J. Xia

DOI

2015

BIRC6 promotes hepatocellular carcinogenesis: Interaction of BIRC6 with p53 facilitating p53 degradation

Wen-Qing Tang, R. Xue, S. Weng, Jian Wu, Ying Fang, Yi Wang, Lingling Ji, Ting-Ting Hu, Tao-Tao Liu, Xiao-Wu Huang, She Chen, Xi-Zhong Shen, Si Zhang, Ling Dong

International Journal of Cancer

DOI

2015

Overexpression of BIRC6 Is a Predictor of Prognosis for Colorectal Cancer

Ting-Ting Hu, S. Weng, Wen-Qing Tang, R. Xue, She Chen, G. Cai, Yu Cai, Xi-Zhong Shen, Si Zhang, Ling Dong

PLoS ONE

DOI

2015

dl -3-n-butylphthalide inhibits platelet activation via inhibition of cPLA2-mediated TXA2synthesis and phosphodiesterase

Jianqin Ye, Lili Zhai, Shenghui Zhang, Yan Zhang, Leilei Chen, Liang Hu, Si Zhang, Zhongren Ding

Platelets

DOI

2015

Caveolin-1 Confers Resistance of Hepatoma Cells to Anoikis by Activating IGF-1 Pathway

Wenqing Tang, Xuemei Feng, Si Zhang, Zhenggang Ren, Yinkun Liu, Biwei Yang, Bei Lv, Yu Cai, Jinglin Xia, Ningling Ge

Cellular Physiology and Biochemistry

DOI

2014

甲氨蝶呤对大鼠脊髓挫伤急性期脂质过氧化的影响

张思，顾兵，王烁宇，李华南，张国福，张水印

《神经药理学报》

2014

Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma

Si Zhang, Wen-Qing Tang, S. Weng, Xijun Liu, B. Rao, Jian-Xin Gu, She Chen, Qun Wang, Xi-Zhong Shen, R. Xue, Ling Dong

OncoTarget

DOI

2014

Toll like receptor 2 knock‐out attenuates carbon tetrachloride (CCl4)‐induced liver fibrosis by downregulating MAPK and NF‐κB signaling pathways

Lingling Ji, R. Xue, Wen-Qing Tang, Weibing Wu, Ting-Ting Hu, Xijun Liu, Xiaomin Peng, Jian-Xin Gu, She Chen, Si Zhang

FEBS Letters

DOI

2014

Bile acids override steatosis in farnesoid X receptor deficient mice in a model of non-alcoholic steatohepatitis.

Weibing Wu, Xijun Liu, Xiaomin Peng, R. Xue, Lingling Ji, Xi-Zhong Shen, She Chen, Jian-Xin Gu, Si Zhang

Biochemical and Biophysical Research Communications - BBRC

DOI

2013

低剂量甲氨蝶呤治疗大鼠脊髓挫伤对神经细胞凋亡的影响

张思，王烁宇，顾兵，李华南，张国福，张水印

《神经药理学报》

2013

诱导多能干细胞及其移植治疗脊髓损伤的研究现状

张思，顾兵，李华南，张国福，张水印，闵友江

《神经药理学报》

2013

Direct interaction between surface β1,4-galactosyltransferase 1 and epidermal growth factor receptor (EGFR) inhibits EGFR activation in hepatocellular carcinoma.

Wen-Qing Tang, S. Weng, Si Zhang, Weibing Wu, Ling Dong, Xi-Zhong Shen, Song-Wen Zhang, Jian-Xin Gu, R. Xue

Biochemical and Biophysical Research Communications - BBRC

DOI

2012

急性脊髓损伤后的氧化应激及其抗氧化治疗

张思，王烁宇，李华南，张国福，顾兵

《神经药理学报》

2012

TreadScan步态分析系统在评价大鼠脊髓挫伤模型中的应用

张思，顾兵，王烁宇，李华南，张国福，张水印

《神经药理学报》

2011

Methotrexate attenuates the Th17/IL-17 levels in peripheral blood mononuclear cells from healthy individuals and RA patients

Yanshan Li, Lindi Jiang, Si Zhang, Lianhua Yin, Lili Ma, Dongyi He, Jie Shen

Rheumatology International

DOI

2008

Investigation of volatile biomarkers in liver cancer blood using solid-phase microextraction and gas chromatography/mass spectrometry.

R. Xue, Ling Dong, Si Zhang, Chunhui Deng, Tao-Tao Liu, Ji-Yao Wang, Xi-Zhong Shen

Rapid Communications in Mass Spectrometry

DOI

2008

Simultaneous determination of blood glucose and isoleucine levels in rats after chronic alcohol exposure by microwave-assisted derivatization and isotope dilution gas chromatography/mass spectrometry.

R. Xue, Si Zhang, Chunhui Deng, Ling Dong, Tao-Tao Liu, Ji-Yao Wang, Hong-Yi Wu, Jian-Xin Gu, Xi-Zhong Shen

Rapid Communications in Mass Spectrometry

DOI

2008

Cdc34-mediated Degradation of ATF5 Is Blocked by Cisplatin

Yuanyan Wei, Jianhai Jiang, Dan Liu, Jin Zhou, Xiaoning Chen, Si Zhang, Hongliang Zong, Xiaojing Yun, Jianxin Gu

Journal of Biological Chemistry

DOI

2007

Functional Interaction of E1AF and Sp1 in Glioma Invasion

Jianhai Jiang, Yuanyan Wei, Jia-Lin Shen, Dan Liu, Xiaoning Chen, Jin Zhou, Hongliang Zong, Xiaojing Yun, Xiangfei Kong, Si Zhang, Yanzhong Yang, Jianxin Gu

Molecular and Cellular Biology

DOI

2006

Down-regulation of β1,4-galactosyltransferase V is a critical part of etoposide-induced apoptotic process and could be mediated by decreasing Sp1 levels in human glioma cells

Jianhai Jiang, Jialin Shen, Tao Wu, Yuanyan Wei, Xiaoning Chen, Hongliang Zong, Si Zhang, Maoyun Sun, Jianhui Xie, Xiangfei Kong, Yanzhong Yang, Aiguo Shen, Hanzhou Wang, Jianxin Gu

Glycobiology

DOI

2006

β1,4-Galactosyltransferase V Functions as a Positive Growth Regulator in Glioma

Jianhai Jiang, Xiaoning Chen, Jia-Lin Shen, Yuanyan Wei, Tao Wu, Yanzhong Yang, Hanzhou Wang, Hongliang Zong, Junwu Yang, Si Zhang, Jianhui Xie, Xiangfei Kong, Weicheng Liu, Jianxin Gu

Journal of Biological Chemistry

DOI

会议论文

2018

Receptor-interacting protein kinase 2(RIP2),a negative regulator of platelet activation and thrombosis

Jianjun Zhang, Zhiling Zhang, Guanxing Pan, Carol Dangelmaier, Lin Chang, Liang Hu, Yan Zhang, Jianlin Qiao, Taei Matsui, Xiaodong Xi, Satya P.Kunapuli, Si Zhang, Zhongren Ding

《首届东方药理论坛暨2018年全国心脑血管药理学术会议、上海市药理学会第十九届学术年会论文集》

DOI

2018

Membrane Akt Phosphorylation Regulates Platelet Aggregation downstream of Gi and G 12/13 Pathways

Yan Zhang, Shuang Zheng, Lin Chang, Zhiling Zhang, Jianjun Zhang, Liang Hu, Si Zhang, Junling Liu, Zhongren Ding

《首届东方药理论坛暨2018年全国心脑血管药理学术会议、上海市药理学会第十九届学术年会》

DOI

2015

Neuronal reprogramming and therapeutic application of NG2 glial precursor cells

Hai-Jie Yang, Pei-Jun Ju, Lei Wang, Si Zhang, Zhi-Wei Feng

《第六届亚太神经科学联合会学术会议暨中国神经科学学会第十一届全国学术会议》

预印本

2025

RIP2 inhibits DOCK8-mediated platelet dense granule release and alleviates experimental myocardial infarction

Jianjun Zhang, Guanxing Pan, Yangyang Liu, Lin Chang, Liang Hu, Zhiyong Qi, Zhiling Zhang, Yan Zhang, Si Zhang, Jianlin Qiao, Xiaodong Xi, Kesheng Dai, Jianzeng Dong, Zhongren Ding

bioRxiv (Cold Spring Harbor Laboratory)

DOI

书籍章节

2015

Role of P2Y12 Receptor in Thrombosis

Yaqi Zhang, Si Zhang, Zhongren Ding

Advances in experimental medicine and biology

DOI

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