王志祥｜中国药科大学｜学者主页

2026

Bayesian Optimization and Kinetic Modeling for Continuous-Flow Synthesis of 4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane Directed by Computational Fluid Dynamics

Nian Chen, Junfeng Zhi, Qiuming Yan, Zhichao Wu, Yichen Shi, Zhixiang Wang, Xiaoming Zha

Organic Process Research & Development

DOI

2025

连续流动生物催化中NAD(P)H再生研究进展

何长安，段金电，王志祥，张全，杨照，胡玉静

《高校化学工程学报》

2024

制药工程学

王志祥

2024

基于核心素养形成的制药工程制图课程思政设计

林文，黄德春，武法文，陈维，王志祥

《药学教育》

2024

Natural flavonoid glycoside-based self-assembled nanoparticles for synergistic antibacterial activity and improved antioxidant properties

Tingyuan Yan, Tingyuan Yan, Wei Yuan, Linxiao Zhang, Zhiyu Li, Jinlei Bian, Davaadagva Damdinjav, Buyankhishig Dorjsuren, Alexander V. Finko, Yanliang Ren, Deqiang Wang, Deqiang Wang, Tingxuan Yan, Tingxuan Yan, Zhixiang Wang

Journal of Drug Delivery Science and Technology

DOI

2024

Preparation of indapamide-HP-β-CD and indapamide-PVP nanoparticles by supercritical antisolvent technology: Experimental and DPD simulations

Changling Lv, Shuang He, Gui He, Xianming Xiong, Congcong Wang, Congcong Wang, Yanliang Ren, Xinya Han, Tingxuan Yan, Zhixiang Wang

The Journal of Supercritical Fluids

DOI

2023

Carboxylated chitosan improved the stability of phycocyanin under acidified conditions

Li Zhuxin, Biao Yuan, Badamkhand Dashnyam, Yifan Cao, Honghong Shan, Xu Xiao, Tan Mingqian, Zhixiang Wang, Cao Chongjiang

International Journal of Biological Macromolecules

DOI

2023

Fabrication of hesperetin/hydroxypropyl-β-cyclodextrin complex nanoparticles for enhancement of bioactivity using supercritical antisolvent technology

Congcong Wang, Tingyuan Yan, Tingyuan Yan, Zhixiang Wang

Journal of Molecular Structure

DOI

2022

Fabrication of betamethasone micro- and nanoparticles using supercritical antisolvent technology: In vitro drug release study and Caco-2 cell cytotoxicity evaluation

Xiangxiang Wang, Shuang He, Kaiye Wang, Xin Wang, Tingyuan Yan, Tingyuan Yan, Tingxuan Yan, Tingxuan Yan, Zhixiang Wang

European Journal of Pharmaceutical Sciences

DOI

2022

Fabrication of apigenin nanoparticles using antisolvent crystallization technology: A comparison of supercritical antisolvent, ultrasonic-assisted liquid antisolvent, and high-pressure homogenization technologies

Tingxuan Yan, Tingxuan Yan, Haili Wang, Xingfang Song, Tingyuan Yan, Tingyuan Yan, Yuwen Ding, Kang Luo, Juan Zhen, Gui He, Libin Nian, Shuangshou Wang, Zhixiang Wang

International Journal of Pharmaceutics

DOI

2022

Preparation of core-shell microcapsules based on microfluidic technology for the encapsulation, protection and controlled delivery of phycocyanin

Xin Wang, Mimi Zhu, Kaiye Wang, Shuang He, Xiaoyue Shi, Biao Yuan, Bin Dong, Zhixiang Wang

Journal of Drug Delivery Science and Technology

DOI

2022

A review of recent strategies to improve the physical stability of phycocyanin

Biao Yuan, Zhuxin Li, Honghong Shan, Badamkhand Dashnyam, Xiao Xu, David Julian McClements, Bingquan Zhang, Mingqian Tan, Zhixiang Wang, Chongjiang Cao

Current Research in Food Science

DOI

2021

工程认证背景下制药工程专业工程制图教学改革

林文，黄德春，江峰，王志祥

《药学教育》

DOI

2021

Inherently nitric oxide containing polymersomes remotely regulated by NIR for improving multi-modal therapy on drug resistant cancer

Zhihong Liu, Yinan Zhong, Xiang Yang Zhou, Xin Huang, Jingjing Zhou, Dechun Huang, Yanfei Li, Zhixiang Wang, Bin Dong, Haishi Qiao, Wei Chen

Biomaterials

DOI

2021

Preparation, characterization and evaluation of the antioxidant capacity and antitumor activity of myricetin microparticles formated by supercritical antisolvent technology

Tingxuan Yan, Yuting Tao, Xiangxiang Wang, Changling Lv, Guizhi Miao, Shuangshou Wang, Deqiang Wang, Zhixiang Wang

The Journal of Supercritical Fluids

DOI

2021

Synthesis of monodisperse spherical AgNPs by ultrasound-intensified Lee-Meisel method, and quick evaluation via machine learning

Bin Dong, Ning Xue, Guohao Mu, Mengjun Wang, Zonghua Xiao, Lin Dai, Zhixiang Wang, Dechun Huang, Hongliang Qian, Wei Chen

Ultrasonics Sonochemistry

DOI

2020

Effect of Different Cooking Methods on Proton Dynamics and Physicochemical Attributes in Spanish Mackerel Assessed by Low-Field NMR

Shan Sun, Siqi Wang, Rong Lin, Shasha Cheng, Biao Yuan, Zhixiang Wang, Mingqian Tan

Foods

DOI

2020

Assessment of Water Mobility in Surf Clam and Soy Protein System during Gelation Using LF-NMR Technique

Siqi Wang, Rong Lin, Shasha Cheng, Zhixiang Wang, Mingqian Tan

Foods

DOI

2019

ZIF-8的制备及其在药物特征响应释放中的应用

刘策，王志祥，武法文

《精细化工》

2019

超临界CO2抗溶剂法制备卡维地洛固体分散体

陈震，周进莉，陶钰婷，王聪聪，占晶晶，王志祥

《中国新药杂志》

DOI

2019

Preparation and characterization of baicalein/hydroxypropyl-β-cyclodextrin inclusion complex for enhancement of solubility, antioxidant activity and antibacterial activity using supercritical antisolvent technology

Tingxuan Yan, Tingxuan Yan, Mengru Ji, Yuxi Sun, Tingyuan Yan, Tingyuan Yan, Jie Zhao, Huiwen Zhang, Zhixiang Wang

Journal of Inclusion Phenomena and Macrocyclic Chemistry

DOI

2019

Preparation of irbesartan composite microparticles by supercritical aerosol solvent extraction system for dissolution enhancement

Tingyuan Yan, Tingyuan Yan, Yi Zhang, Mengru Ji, Zhixiang Wang, Tingxuan Yan, Tingxuan Yan

The Journal of Supercritical Fluids

DOI

2018

Micronization of Gefitinib Using Solution‐Enhanced Dispersion by Supercritical CO2

Jing Zhang, Qiming Wang, Zhonglin Zhu, Hongliang Qian, Feng Jiang, Zhixiang Wang, Wei Liu, Dechun Huang

Chemical Engineering & Technology

DOI

2018

Quantitative Design of Seed Load Based on model identification of nucleation and crystal growth stages without transmittance data

Hongliang Qian, Lin Dai, Feng Jiang, Yiqiang Shi, Zhixiang Wang, Wei Liu, Dechun Huang, Wei Chen

Powder Technology

DOI

2017

超临界CO2抗溶剂法制备微粉化阿西美辛

颜亭辕，林文，宋杏芳，颜庭轩，王志祥

《中国医药工业杂志》

2017

新形势下高校《制药工程制图》课程教学改革与实践

钱红亮，祝忠林，秦琲琛，黄德春，王志祥

《教育教学论坛》

2017

Preparation and characterization of naringenin microparticles via a supercritical anti-Solvent process

Honggang Miao, Zhen Xing Chen, Wenbo Xu, Weiyan Wang, Yaqin Song, Zhixiang Wang

The Journal of Supercritical Fluids

DOI

2016

制药工程原理与设备

王志祥

《人民卫生出版社》

2016

Micronization of etoposide using solution-enhanced dispersion by supercritical CO2

Yue Cheng, Wenbo Xu, Zhen Chen, Zhixiang Wang, Dechun Huang

The Journal of Supercritical Fluids

DOI

2016

Effect of ultrasonication on the dilution crystallization of naproxen

Huamin Zhang, Zhixiang Wang, Huidan Huang, Zhiqin Cui, Dechun Huang

Separation Science and Technology

DOI

2015

碱蓬籽油脂的超临界CO2提取工艺优化

陈然然，邵荣，杨剑，王志祥

《化学工程师》

2015

异长叶烯酮合成条件优化及动力学

王占军，武法文，王志祥，鲁凯强

《化工进展》

DOI

2015

Preparation and characterization of baicalein powder micronized by the SEDS process

Tingxuan Yan, Yue Cheng, Zhixiang Wang, Dechun Huang, Honggang Miao, Yi Zhang

The Journal of Supercritical Fluids

DOI

2014

超临界流体技术制备辛伐他汀/PLLA-PEG缓释复合微球

颜庭轩，王志祥，黄德春，宋杏芳

《高校化学工程学报》

2014

超临界抗溶剂法研制卡马西平微粒

潘丁丁，颜庭轩，王志祥，黄德春，党蓓蕾

《中国医药工业杂志》

2014

基于卓越计划的制药工程专业课程与实践体系探讨

戴琳，王志祥，黄德春，林文，李想

《药学教育》

2012

超临界抗溶剂制粒装置的现状及其展望

巫先坤，王志祥，黄德春，蔡锦源，颜庭轩

《化工进展》

2012

超临界CO2抗溶剂法制备布洛芬/EC-PVP缓释复合微粒

蔡锦源，黄德春，王志祥，党蓓蕾，王秋玲，苏鑫光

《药学学报》

2012

Optimal extraction process of Salidroside from Ligustrum Lucidum by orthogonal Test

Zhixiang Wang

Strait Pharmaceutical Journal

2011

微波真空干燥技术及设备

蔡锦源，巫先坤，周黎明，王明明，王志祥

《机电信息》

2011

Optimization of ultrasound-assisted extraction capsicum red pigment from Capsicum frutescens L. via response surface methodology

Zhixiang Wang

Zhongguo yaoke daxue xuebao

2011

Study on The Extraction of Oligosaccharides from Yacon by Microwave-assisted Extraction

Zhixiang Wang

Chinese Journal of Pharmacovigilance

2010

真空冷冻干燥技术及其在制药行业中的应用

林文，王志祥

《机电信息》

2010

制药工程制图课程教学的探索与实践

江峰，王志祥，于颖

《化工时刊》

2009

异长叶烯酮的绿色合成

武法文，王志祥，李磊，张志炳

《精细化工》

2009

喷雾干燥技术及其在制药工业的应用

林文，王志祥

《机电信息》

2008

惰性粒子流化干燥技术及其应用

赵思昆，刘巍，戴琳，王志祥

《化工时刊》

2007

超临界流体抗溶剂结晶技术在药物制粒领域中的应用

乐龙，黄德春，刘巍，王志祥

《药学进展》

2006

红外热像法研究降膜流动

张锋，耿皎，赵贤广，王志祥，张志炳

《化工进展》

2006

溶液间歇结晶动力学模型的新型算法

黄德春，王志祥，刘巍，孙岳明

《化学学报》

2006

分子蒸馏设备的现状及其展望

王志祥，林文，于颖

《化工进展》

2006

未添加晶种结晶过程的中后期动力学模拟

黄德春，王志祥，刘巍，孙岳明

《化学学报》

2004

制药工程学教材的内容和特点

王志祥，黄德春

《药学教育》

2003

超低分压下CO2在NaOH和Na2CO3水溶液中的溶解度

骆培成，王志祥，杨照，焦真，张志炳

《化学工程》

精选作品

期刊论文

Bayesian Optimization and Kinetic Modeling for Continuous-Flow Synthesis of 4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane Directed by Computational Fluid Dynamics

连续流动生物催化中NAD(P)H再生研究进展

制药工程学

基于核心素养形成的制药工程制图课程思政设计

Natural flavonoid glycoside-based self-assembled nanoparticles for synergistic antibacterial activity and improved antioxidant properties

Preparation of indapamide-HP-β-CD and indapamide-PVP nanoparticles by supercritical antisolvent technology: Experimental and DPD simulations

Carboxylated chitosan improved the stability of phycocyanin under acidified conditions

Fabrication of hesperetin/hydroxypropyl-β-cyclodextrin complex nanoparticles for enhancement of bioactivity using supercritical antisolvent technology

Fabrication of betamethasone micro- and nanoparticles using supercritical antisolvent technology: In vitro drug release study and Caco-2 cell cytotoxicity evaluation

Fabrication of apigenin nanoparticles using antisolvent crystallization technology: A comparison of supercritical antisolvent, ultrasonic-assisted liquid antisolvent, and high-pressure homogenization technologies

Preparation of core-shell microcapsules based on microfluidic technology for the encapsulation, protection and controlled delivery of phycocyanin

A review of recent strategies to improve the physical stability of phycocyanin

工程认证背景下制药工程专业工程制图教学改革

Inherently nitric oxide containing polymersomes remotely regulated by NIR for improving multi-modal therapy on drug resistant cancer

Preparation, characterization and evaluation of the antioxidant capacity and antitumor activity of myricetin microparticles formated by supercritical antisolvent technology

Synthesis of monodisperse spherical AgNPs by ultrasound-intensified Lee-Meisel method, and quick evaluation via machine learning

Effect of Different Cooking Methods on Proton Dynamics and Physicochemical Attributes in Spanish Mackerel Assessed by Low-Field NMR

Assessment of Water Mobility in Surf Clam and Soy Protein System during Gelation Using LF-NMR Technique

ZIF-8的制备及其在药物特征响应释放中的应用

超临界CO2抗溶剂法制备卡维地洛固体分散体

Preparation and characterization of baicalein/hydroxypropyl-β-cyclodextrin inclusion complex for enhancement of solubility, antioxidant activity and antibacterial activity using supercritical antisolvent technology

Preparation of irbesartan composite microparticles by supercritical aerosol solvent extraction system for dissolution enhancement

Micronization of Gefitinib Using Solution‐Enhanced Dispersion by Supercritical CO2

Quantitative Design of Seed Load Based on model identification of nucleation and crystal growth stages without transmittance data

超临界CO2抗溶剂法制备微粉化阿西美辛

新形势下高校《制药工程制图》课程教学改革与实践

Preparation and characterization of naringenin microparticles via a supercritical anti-Solvent process

制药工程原理与设备

Micronization of etoposide using solution-enhanced dispersion by supercritical CO2

Effect of ultrasonication on the dilution crystallization of naproxen

碱蓬籽油脂的超临界CO2提取工艺优化

异长叶烯酮合成条件优化及动力学

Preparation and characterization of baicalein powder micronized by the SEDS process

超临界流体技术制备辛伐他汀/PLLA-PEG缓释复合微球

超临界抗溶剂法研制卡马西平微粒

基于卓越计划的制药工程专业课程与实践体系探讨

超临界抗溶剂制粒装置的现状及其展望

超临界CO2抗溶剂法制备布洛芬/EC-PVP缓释复合微粒

Optimal extraction process of Salidroside from Ligustrum Lucidum by orthogonal Test

微波真空干燥技术及设备

Optimization of ultrasound-assisted extraction capsicum red pigment from Capsicum frutescens L. via response surface methodology

Study on The Extraction of Oligosaccharides from Yacon by Microwave-assisted Extraction

真空冷冻干燥技术及其在制药行业中的应用

制药工程制图课程教学的探索与实践

异长叶烯酮的绿色合成

喷雾干燥技术及其在制药工业的应用

惰性粒子流化干燥技术及其应用

超临界流体抗溶剂结晶技术在药物制粒领域中的应用

红外热像法研究降膜流动

溶液间歇结晶动力学模型的新型算法

分子蒸馏设备的现状及其展望

未添加晶种结晶过程的中后期动力学模拟

制药工程学教材的内容和特点

超低分压下CO2在NaOH和Na2CO3水溶液中的溶解度