唐姗｜中国科学技术大学｜学者主页

2026

Traceless sortase ligation for chemical protein synthesis

Yong-Kang Zhou, Dong Huang, Weichen Wang, Shijun Zou, Guoxia Yu, Long Wang, Leilei Shi, Shan Tang, Ji-Shen Zheng

Nature Synthesis

2025

Mechanically Triggered Protein Desulfurization.

Dongyang Han, Yan Cui, Xiangyu Deng, Chun-Tong Li, Xianglai Zhu, Bingji Wang, Guo-Chao Chu, Zhipeng A Wang, Shan Tang, Ji-Shen Zheng, Lu-Jun Liang, Lei Liu

Journal of the American Chemical Society

DOI

2024

An Enzyme-Cleavable Solubilizing-Tag Facilitates the Chemical Synthesis of Mirror-Image Proteins.

Yu-Peng Zheng, Baochang Zhang, Weiwei Shi, Xiangyu Deng, Tongyue Wang, Dongyang Han, Yuxiang Ren, Zi-Yi Yang, Yong-Kang Zhou, Jian Kuang, Zhi-wen Wang, Shan Tang, Ji-Shen Zheng

Angewandte Chemie

DOI

2024

L-Glycosidase-Cleavable Natural Glycans Facilitate the Chemical Synthesis of Correctly Folded Disulfide-Bonded D-Proteins.

Weiwei Shi, Tongyue Wang, Yangzi Yang, Yuxiang Ren, Dongyang Han, Yu-Peng Zheng, Xiangyu Deng, Shan Tang, Ji-Shen Zheng

Angewandte Chemie

DOI

2024

Capturing acyl–enzyme intermediates with genetically encoded 2,3-diaminopropionic acid for hydrolase substrate identification

Juan Luo, Yao-Chuan Yu, Ke Wang, Sizhe He, Long Wang, Fangfang Liang, Jason W. Chin, Shan Tang

Nature Protocols

DOI

2024

Enhanced native chemical ligation by peptide conjugation in trifluoroacetic acid

Dong Huang, Wu-Chen Guo, Weiwei Shi, Yun-Pu Gao, Yong-Kang Zhou, Long Wang, Chen Wang, Shan Tang, Lei Liu, Ji-Shen Zheng

Science Advances

DOI

2024

Recent advances in chemical protein synthesis: method developments and biological applications

Suwei Dong, Ji-Shen Zheng, Yi-Ming Li, Huan Wang, Gong Chen, Yongxiang Chen, Ge-Min Fang, Jun Guo, Chunmao He, Honggang Hu, Xuechen Li, Yan-Mei Li, Zi-Gang Li, Man Pan, Shan Tang, Chang-Lin Tian, Ping Wang, Bian Wu, Chuan-Liu Wu, Jun-Feng Zhao, Lei Liu

Science China Chemistry

DOI

2023

Chemical synthesis of a 28 kDa full-length PET degrading enzyme ICCG by the removable backbone modification strategy.

Yun-Pu Gao, Peng Sun, Wu-Chen Guo, Yong-Kang Zhou, Ji-Shen Zheng, Shan Tang

Bioorganic chemistry (Print)

DOI

2023

Backbone‐Installed Split Intein‐Assisted Ligation for the Chemical Synthesis of Mirror‐Image Proteins

Baochang Zhang, Yupeng Zheng, Guo‐Chao Chu, Xiangyu Deng, Tongyue Wang, Weiwei Shi, Yongkang Zhou, Shan Tang, Ji‐Shen Zheng, Lei Liu

Angewandte Chemie

DOI

2023

Capturing Covalent Catalytic Intermediates by Enzyme Mutants: Recent Advances in Methodologies and Applications

Yongchao Wang, Shan Tang

ChemBioChem

DOI

2018

Tuning radical reactivity for selective radical/radical cross-coupling

Shengchun Wang, Shan Tang, Aiwen Lei

Science Bulletin

2018

Biochemical properties of K11,48-branched ubiquitin chains

Lujun Liang, Yanyan Si, Shan Tang, Dong‐Liang Huang, Zhipeng A. Wang, Changlin Tian, Ji‐Shen Zheng

Chinese Chemical Letters

DOI

2017

One-pot ligation strategy for atypical ubiquitin chains synthesis by using the trifluoroacetamidomethyl-protected isopeptide-linked Ub (Tfacm-isoUb) unit

Yanyan Si, Lujun Liang, Shan Tang, Yun‐Kun Qi, Yong Huang, Ji‐Shen Zheng

Tetrahedron Letters

DOI

2015

Oxidative cross-coupling: an alternative way for C–C bond formations

Zhiyuan Huang, Shan Tang, Aiwen Lei

Science Bulletin

唐姗

精选作品

期刊论文

Traceless sortase ligation for chemical protein synthesis

Mechanically Triggered Protein Desulfurization.

An Enzyme-Cleavable Solubilizing-Tag Facilitates the Chemical Synthesis of Mirror-Image Proteins.

L-Glycosidase-Cleavable Natural Glycans Facilitate the Chemical Synthesis of Correctly Folded Disulfide-Bonded D-Proteins.

Capturing acyl–enzyme intermediates with genetically encoded 2,3-diaminopropionic acid for hydrolase substrate identification

Enhanced native chemical ligation by peptide conjugation in trifluoroacetic acid

Recent advances in chemical protein synthesis: method developments and biological applications

Chemical synthesis of a 28 kDa full-length PET degrading enzyme ICCG by the removable backbone modification strategy.

Backbone‐Installed Split Intein‐Assisted Ligation for the Chemical Synthesis of Mirror‐Image Proteins

Capturing Covalent Catalytic Intermediates by Enzyme Mutants: Recent Advances in Methodologies and Applications

Tuning radical reactivity for selective radical/radical cross-coupling

Biochemical properties of K11,48-branched ubiquitin chains

One-pot ligation strategy for atypical ubiquitin chains synthesis by using the trifluoroacetamidomethyl-protected isopeptide-linked Ub (Tfacm-isoUb) unit

Oxidative cross-coupling: an alternative way for C–C bond formations

研究方向