李婉南｜吉林大学｜学者主页

2026

Panax ginseng-derived peptides as natural dipeptidyl peptidase-IV inhibitors: screening, binding mechanisms, and potential for glycemic management in functional foods

Yan Zhang, Yuenan Xing, Xiaoli Shen, Wannan Li, Xin Li (51274), Yue Jin, Weiwei Han

npj Science of Food

DOI

2026

Machine learning-driven classification of bioactive peptides and their molecular basis for sour taste perception

Huizi Cui, Cheng Cheng, Yuxuan Wang, Xueqi Fu, Wenfu Yan, Wannan Li, Weiwei Han

Journal of Dairy Science

DOI

2025

乌头汤及其配伍对抗类风湿性关节炎的机制

姜永新，刘凯丰，胡成祥，李婉南，韩葳葳

《吉林大学学报(理学版)》

DOI

2025

Precision in Predicting Protein–Nucleic Acid Complexes: Establishing a Benchmark Data Set and Comparative Metrics

Huizi Cui, Yuxuan Wang, Yu Fu, Xiangyu Yu, Wannan Li, Feng Lin, Weiwei Han

Journal of Chemical Information and Modeling

DOI

2025

Mechanistic Study of Protein Interaction with Natto Inhibitory Peptides Targeting Xanthine Oxidase: Insights from Machine Learning and Molecular Dynamics Simulations

Minghao Liu, Kaiyu Wang, Yan Zhang, Xue Zhou, Wannan Li, Weiwei Han

Journal of Chemical Information and Modeling

DOI

2025

Exploring Hidden Dangers: Predicting Mycotoxin-like Toxicity and Mapping Toxicological Networks in Hepatocellular Carcinoma

Jian Xiu, Hengzheng Yang, Xiaoli Shen, Yuenan Xing, Wannan Li, Weiwei Han

Journal of Chemical Information and Modeling

DOI

2025

Virtual screening of sweet peptides from milk protein and molecular dynamics simulations mechanism analysis

Sainan Yu, Yuyang Liu, Xueqi Fu, Wenfu Yan, Wenwen Gao, Wannan Li, Weiwei Han

Journal of Dairy Science

DOI

2025

Pred5AOP: an efficient screening of food-derived antioxidant peptides based on deep learning, molecular docking, and experimental validation

Yan Zhang, Yi Jie He, Shihong Li, Wannan Li, Weiwei Han

Food Chemistry

DOI

2025

Virtual Hydrolysis-Based Screening of Wheat-Derived DPP-IV Inhibitory Peptides: A Mechanistic Analysis Integrating Cell Experiments and Molecular Dynamics Simulations

Yuyang Liu, Yan Zhang, Minghao Liu, Sainan Yu, Zhenglin Tian, Wannan Li, Weiwei Han

Journal of Agricultural and Food Chemistry

DOI

2025

Deep learning-based dipeptidyl peptidase IV inhibitor screening, experimental validation, and GaMD/LiGaMD analysis

Yi Jie He, Yan Zhang, Minghao Liu, Jiaying Li, Wannan Li, Weiwei Han

BMC Biology

DOI

2025

Screening and characterization of antioxidant peptides from Ganoderma lucidum: Virtual prediction, experimental validation, and mechanistic insights

Minghao Liu, Yan Zhang, Jiuliang Yang, Xue Zhou, Wannan Li, Weiwei Han

Food Bioscience

DOI

2025

Predicting cardiotoxicity in drug development: A deep learning approach

Kaifeng Liu, Huizi Cui, Xiangyu Yu, Wannan Li, Weiwei Han

Journal of Pharmaceutical Analysis

DOI

2025

Therapeutic Potential and Mechanistic Insights of Sunflower Receptacles’ Essential Oil Against Gout: An In-Depth Molecular Study

Kaiyu Wang, Xue Bai, Hengzheng Yang, Kaifeng Liu, Lu Han, Wannan Li, Weiwei Han

Communications in Computational Chemistry

DOI

2025

Elucidating the Mechanism of VVTT Infection Through Machine Learning and Transcriptome Analysis

Zhili Chen, Yongxin Jiang, Jiazhen Cui, Wannan Li, Weiwei Han, Gang Liu

International Journal of Molecular Sciences

DOI

2025

Artificial Intelligence-Aided Virtual Screening and Molecular Dynamics Analysis of Novel Xanthine Oxidase Inhibitory Peptides Derived from Sunflower ( Helianthus annuus ) Proteins

Kaiyu Wang, Minghao Liu, Yan Zhang, Wannan Li, Weiwei Han

Journal of Agricultural and Food Chemistry

DOI

2025

Screening and analysis of malt pentapeptide DPP-IV inhibitory activity

Yi He, Yan Zhang, Pengying Zhang, Jiaying Li, Wannan Li, Weiwei Han

npj Science of Food

DOI

2025

Screening and Validation: AI-Aided Discovery of Dipeptidyl Peptidase-4 Inhibitory Peptides from Hydrolyzed Rice Proteins

Cheng Cheng, Huizi Cui, Xiangyu Yu, Wannan Li

Foods

DOI

2025

Unveiling drug-induced osteotoxicity: A machine learning approach and webserver

Huizi Cui, Yi He, Zhibang Wang, Kaifeng Liu, Wannan Li, Weiwei Han

Journal of Hazardous Materials

DOI

2024

Investigation of the efficacy of sunflower receptacle flavonoids in treating hyperuricemia: an integrated approach

Kaiyu Wang, Kaifeng Liu, Huizi Cui, Xueqi Fu, Wannan Li, Weiwei Han

Food Science and Human Wellness

DOI

2024

Unveiling the Anti-Obesity Potential of Thunder God Vine: Network Pharmacology and Computational Insights into Celastrol-like Molecules

Siyun Zheng, Hengzheng Yang, Jingxian Zheng, Yidan Wang, Bo Jia, Wannan Li

International Journal of Molecular Sciences

DOI

2024

Antioxidant activity of soybean peptides and Keap1 protein: A combined in vitro and in silico analysis

Yan Zhang, Yuyang Liu, Wannan Li, Weiwei Han

LWT

DOI

2024

GPT4Kinase: High-accuracy prediction of inhibitor-kinase binding affinity utilizing large language model

Kaifeng Liu, Xiangyu Yu, Huizi Cui, Wannan Li, Weiwei Han

International Journal of Biological Macromolecules

DOI

2024

Specific Substrate Activity of Lotus Root Polyphenol Oxidase: Insights from Gaussian-Accelerated Molecular Dynamics and Markov State Models

Minghao Liu, Siyun Zheng, Yijia Tang, Weiwei Han, Wannan Li, Tao Li

International Journal of Molecular Sciences

DOI

2024

Computational Insights into Reproductive Toxicity: Clustering, Mechanism Analysis, and Predictive Models

Huizi Cui, Qizheng He, Wannan Li, Yuying Duan, Weiwei Han

International Journal of Molecular Sciences

DOI

2024

Elucidating the structural basis of vitamin B12 derivatives as novel potent inhibitors of PTP1B: Insights from inhibitory mechanisms using Gaussian accelerated molecular dynamics (GaMD) and in vitro study

Wencheng Zhao, Hengzheng Yang, Huizi Cui, Wannan Li, Shu Xing, Weiwei Han

International Journal of Biological Macromolecules

DOI

2024

Mulberry Leaf Compounds and Gut Microbiota in Alzheimer’s Disease and Diabetes: A Study Using Network Pharmacology, Molecular Dynamics Simulation, and Cellular Assays

Xue Bai, Xinyi Zhao, Kaifeng Liu, Xiaotang Yang, Qizheng He, Yilin Gao, Wannan Li, Weiwei Han

International Journal of Molecular Sciences

DOI

2024

Unveiling Anti-Diabetic Potential of Baicalin and Baicalein from Baikal Skullcap: LC–MS, In Silico, and In Vitro Studies

Wencheng Zhao, Huizi Cui, Kaifeng Liu, Xiaotang Yang, Shu Xing, Wannan Li

International Journal of Molecular Sciences

DOI

2024

Exploring the anti-gout potential of sunflower receptacles alkaloids: A computational and pharmacological analysis

Kaiyu Wang, Huizi Cui, Kaifeng Liu, Qizheng He, Xueqi Fu, Wannan Li, Weiwei Han

Computers in Biology and Medicine

DOI

2024

Study on the Mechanism of Interaction between Dipeptidyl Peptidase 4 and Inhibitory Peptides Based on Gaussian Accelerated Molecular Dynamic Simulation

Yuyang Liu, Wencheng Zhao, Yongxin Jiang, Shu Xing, Wannan Li

International Journal of Molecular Sciences

DOI

2024

Using deep learning and molecular dynamics simulations to unravel the regulation mechanism of peptides as noncompetitive inhibitor of xanthine oxidase

Yi Jie He, Kaifeng Liu, Fuyan Cao, Renxiu Song, Jianxuan Liu, Yinghua Zhang, Wannan Li, Weiwei Han

Scientific Reports

DOI

2024

Interactions between Inhibitors and 5-Lipoxygenase: Insights from Gaussian Accelerated Molecular Dynamics and Markov State Models

Yuyang Liu, Kaiyu Wang, Fuyan Cao, Nan Gao, Wannan Li

International Journal of Molecular Sciences

DOI

2024

Molecular insights into chronic atrophic gastritis treatment: Coptis chinensis Franch studied via network pharmacology, molecular dynamics simulation and experimental analysis

Chengxiang Hu, Fuyan Cao, Yongxin Jiang, Kaifeng Liu, Tao Li, Tao Li, Yin Han Gao, Wannan Li, Weiwei Han

Computers in Biology and Medicine

DOI

2024

VmmScore: An umami peptide prediction and receptor matching program based on a deep learning approach

Minghao Liu, Jiuliang Yang, Yi He, Fuyan Cao, Wannan Li, Weiwei Han

Computers in Biology and Medicine

DOI

2023

基于桑黄对肺炎的治疗作用及其机制的网络药理学分析

刘雨萌，冷嵩，萨仁高娃，林黛洁，谢林盛，李梦睿，许肖，李婉南

《吉林大学学报(医学版)》

DOI

2023

Probing the mechanisms of hydrazide-based HDAC inhibitors binding to HDAC3 using Gaussian accelerated molecular dynamics (GaMD) simulations

Fangfang Guo, Hengzheng Yang, Xue Bai, Jiaying Li, Weiwei Han, Wannan Li

Journal of Biomolecular Structure and Dynamics

DOI

2023

Network Pharmacology Combined with Machine Learning to Reveal the Action Mechanism of Licochalcone Intervention in Liver Cancer

Fangfang Guo, Xiaotang Yang, Chengxiang Hu, Wannan Li, Weiwei Han

International Journal of Molecular Sciences

DOI

2023

Functionalized Fullerene Potentially Inhibits SARS-CoV-2 Infection by Modulating Spike Protein Conformational Changes

Kaifeng Liu, Fangfang Guo, Yingying Ma, Xiangyu Yu, Xueqi Fu, Wannan Li, Weiwei Han

International Journal of Molecular Sciences

DOI

2023

Network pharmacology and experiment indicated that medicinal food homologous components play important roles in insomnia

Xiao Xu, Yang Liu, Xueqi Fu, Guodong Li, Weiwei Han, Wannan Li

Food Frontiers

DOI

2023

Investigating the Vital Role of the Identified Abietic Acid from Helianthus annuus L. Calathide Extract against Hyperuricemia via Human Embryonic Kidney 293T Cell Model

Huining Dai, Xiao Xu, Wannan Li, Xueqi Fu, Weiwei Han, Guodong Li

Molecules

DOI

2022

In Silico Discovery of Anticancer Peptides from Sanghuang

Minghao Liu, Jiachen Lv, Liyuan Chen, Wannan Li, Weiwei Han

International Journal of Molecular Sciences

DOI

2022

The Active Components of Sunflower (Helianthus annuus L.) Calathide and the Effects on Urate Nephropathy Based on COX-2/PGE2 Signaling Pathway and the Urate Transporter URAT1, ABCG2, and GLUT9

Huining Dai, Shuai Lv, Zian Qiao, Kaiyu Wang, Zhou Xipeng, Chunyang Bao, Shitao Zhang, Xueqi Fu, Wannan Li

Frontiers in Nutrition

DOI

2021

基于拉伸分子动力学模拟的黄嘌呤氧化酶抑制剂解离途径的理论研究

齐人睿，李明昊，常浩，付学奇，高波，韩葳葳，韩璐，李婉南

《高等学校化学学报》

2021

基于分子动力学模拟的VmoLac非特异性底物催化活性的理论研究

李聪聪，刘明皓，韩佳睿，朱镜璇，韩葳葳，李婉南

《高等学校化学学报》

2021

Chemical Compounds, Antioxidant Activities, and Inhibitory Activities Against Xanthine Oxidase of the Essential Oils From the Three Varieties of Sunflower (Helianthus annuus L.) Receptacles

Xinsheng Liu, Bo Gao, Zhan-De Dong, Zian Qiao, Min Yan, Weiwei Han, Wannan Li, Lu Han

Frontiers in Nutrition

DOI

2021

Identification of Scopoletin and Chlorogenic Acid as Potential Active Components in Sunflower Calathide Enzymatically Hydrolyzed Extract towards Hyperuricemia

Huining Dai, Shuai Lv, Xueqi Fu, Wannan Li

Applied Sciences

DOI

2021

Molecular Dynamics Simulations Study of the Interactions between Human Dipeptidyl-Peptidase III and Two Substrates

Shitao Zhang, Shuai Lv, Xueqi Fu, Lu Han, Weiwei Han, Wannan Li

Molecules

DOI

2021

Targeting N-Terminal Human Maltase-Glucoamylase to Unravel Possible Inhibitors Using Molecular Docking, Molecular Dynamics Simulations, and Adaptive Steered Molecular Dynamics Simulations

Shitao Zhang, Yi Wang, Lu Han, Xueqi Fu, Song Wang, Wannan Li, Weiwei Han

Frontiers in Chemistry

DOI

2021

In silico study to predict potential precursors of human dipeptidyl peptidase-IV inhibitors from hazelnut

Congcong Li, Renrui Qi, Jiawei Yuan, Lu Han, Song Wang, Wannan Li, Weiwei Han

Journal of Biomolecular Structure and Dynamics

DOI

2021

Protective effect of Phaeoporus obliquus polysaccharide against acute liver injury induced by carbon tetrachloride and alcohol in mice.

Lei Zhang, Ren Xiao-Hong, He Jing, Wannan Li, Hao Jing-Wei, Yunrong Jing, Chai Jun-Rong, Xiaowei Sun, Wan Chun-Lei

PubMed

2021

Conformational Changes of Glutamine 5′-Phosphoribosylpyrophosphate Amidotransferase for Two Substrates Analogue Binding: Insight from Conventional Molecular Dynamics and Accelerated Molecular Dynamics Simulations

Congcong Li, Siao Chen, Tianci Huang, Fangning Zhang, Jiawei Yuan, Hao Chang, Wannan Li, Weiwei Han

Frontiers in Chemistry

DOI

2021

Extraction, Radical Scavenging Activities, and Chemical Composition Identification of Flavonoids from Sunflower (Helianthus annuus L.) Receptacles

Zian Qiao, Lu Han, Xinsheng Liu, Huining Dai, Changmin Liu, Min Yan, Wannan Li, Weiwei Han, Xinlu Li, Silu Huang, Bo Gao

Molecules

DOI

2020

Chemical Composition and Antimicrobial and Antioxidant Activities of Essential Oil of Sunflower (Helianthus annuus L.) Receptacle

Xinsheng Liu, Xinlu Li, Zian Qiao, Wannan Li, Bo Gao, Lu Han

Molecules

DOI

2018

Identification of common differentially‑expressed miRNAs in ovarian cancer cells and their exosomes compared with normal ovarian surface epithelial cell cells

Shitao Zhang, Xiaoping Zhang, Xueqi Fu, Wannan Li, Shu Xing, Yiling Yang

Oncology Letters

DOI

2018

Knockdown of LMW-PTP enhances stress resistance in Caenorhabditis elegans

Lin Zhou, Lu Wang, Shuju Bai, Shu Xing, Wannan Li, Junfeng Ma, Xueqi Fu

International Journal of Biological Macromolecules

DOI

2018

Hypoglycemic effect and mechanism of isoquercitrin as an inhibitor of dipeptidyl peptidase-4 in type 2 diabetic mice

Lei Zhang, Shi-Tao Zhang, Yanchun Yin, Shu Xing, Wannan Li, Xueqi Fu

RSC Advances

DOI

2017

Arbutin increases Caenorhabditis elegans longevity and stress resistance

Lin Zhou, Xueqi Fu, Liyan Jiang, Lu Wang, Shuju Bai, Yan Jiao, Shu Xing, Wannan Li, Junfeng Ma

PeerJ

DOI

2017

2-SeCD treatment extends lifespan, improves healthspan and enhances resistance to stress in Caenorhabditis elegans

Lin Zhou, Xueqi Fu, Yi Luo, Fangzhou Du, Hua Wang, Shu Xing, Wannan Li, Junfeng Ma

RSC Advances

DOI

2015

Identification of key genes associated with the effect of estrogen on ovarian cancer using microarray analysis

Shitao Zhang, Chao Zuo, Wannan Li, Xueqi Fu, Shu Xing, Xiao-ping Zhang

Archives of Gynecology and Obstetrics

DOI

2015

Association of ACP1 gene polymorphisms and coronary artery disease in northeast Chinese population

TIANBAO LI, Xuesong Xu, Jianzhuo Li, Shu Xing, LIN ZHANG, Wannan Li, Junfeng Ma, Xueqi Fu

Journal of Genetics

DOI

2015

Magnolia officinalisExtract Contains Potent Inhibitors against PTP1B and Attenuates Hyperglycemia in db/db Mice

Jing Sun, Yongsen Wang, Xueqi Fu, Yingli Chen, Deli Wang, Wannan Li, Shu Xing, Guodong Li

BioMed Research International

DOI

2014

Expression, purification, and characterization of human osteoclastic protein-tyrosine phosphatase catalytic domain in Escherichia coli

Huan Jiang, Yuan Sui, Yue Cui, Peng Lin, Wannan Li, Shu Xing, Deli Wang, Min Hu, Xueqi Fu

Protein Expression and Purification

DOI

2013

丁香对胰岛素信号通路的影响及2型糖尿病降糖机制的研究

张蕾，曾睍阳，刘悦龙，张师桃，孙婧，王永森，李婉南，付学奇

《长春中医药大学学报》

2013

巨核细胞蛋白质酪氨酸磷酸酶2的克隆表达及其与骨质疏松症的关系

张蕾，张师桃，曾晛阳，张小平，郝凡凡，王丰，李婉南，付学奇

《吉林大学学报(医学版)》

2013

超高效液相色谱串联质谱联用法快速筛选3-羟基-3-甲基戊二酰辅酶A还原酶抑制剂

吴琼，王世聪，马俊锋，李婉南，邢述，付学奇

《分析化学》

2008

蛋白质酪氨酸磷酸酶SHP-1的中药抑制剂筛选

李婉南，李莹，庄妍，李贺，陈颖丽，赵志壮，付学奇

《吉林大学学报(理学版)》

2008

蛋白质酪氨酸磷酸酶SHP-1催化结构域的克隆表达及抑制剂筛选

李婉南

《吉林大学》

2008

蛋白质酪氨酸磷酸酶及相关疾病

李婉南，姜轶群，范晓迪，董洪钵

《吉林大学学报(医学版)》

DOI

2005

人SHP-1催化结构域的克隆表达及其多克隆抗体的制备

李婉南

《吉林大学》

精选作品

期刊论文

Panax ginseng-derived peptides as natural dipeptidyl peptidase-IV inhibitors: screening, binding mechanisms, and potential for glycemic management in functional foods

Machine learning-driven classification of bioactive peptides and their molecular basis for sour taste perception

乌头汤及其配伍对抗类风湿性关节炎的机制

Precision in Predicting Protein–Nucleic Acid Complexes: Establishing a Benchmark Data Set and Comparative Metrics

Mechanistic Study of Protein Interaction with Natto Inhibitory Peptides Targeting Xanthine Oxidase: Insights from Machine Learning and Molecular Dynamics Simulations

Exploring Hidden Dangers: Predicting Mycotoxin-like Toxicity and Mapping Toxicological Networks in Hepatocellular Carcinoma

Virtual screening of sweet peptides from milk protein and molecular dynamics simulations mechanism analysis

Pred5AOP: an efficient screening of food-derived antioxidant peptides based on deep learning, molecular docking, and experimental validation

Virtual Hydrolysis-Based Screening of Wheat-Derived DPP-IV Inhibitory Peptides: A Mechanistic Analysis Integrating Cell Experiments and Molecular Dynamics Simulations

Deep learning-based dipeptidyl peptidase IV inhibitor screening, experimental validation, and GaMD/LiGaMD analysis

Screening and characterization of antioxidant peptides from Ganoderma lucidum: Virtual prediction, experimental validation, and mechanistic insights

Predicting cardiotoxicity in drug development: A deep learning approach

Therapeutic Potential and Mechanistic Insights of Sunflower Receptacles’ Essential Oil Against Gout: An In-Depth Molecular Study

Elucidating the Mechanism of VVTT Infection Through Machine Learning and Transcriptome Analysis

Artificial Intelligence-Aided Virtual Screening and Molecular Dynamics Analysis of Novel Xanthine Oxidase Inhibitory Peptides Derived from Sunflower ( Helianthus annuus ) Proteins

Screening and analysis of malt pentapeptide DPP-IV inhibitory activity

Screening and Validation: AI-Aided Discovery of Dipeptidyl Peptidase-4 Inhibitory Peptides from Hydrolyzed Rice Proteins

Unveiling drug-induced osteotoxicity: A machine learning approach and webserver

Investigation of the efficacy of sunflower receptacle flavonoids in treating hyperuricemia: an integrated approach

Unveiling the Anti-Obesity Potential of Thunder God Vine: Network Pharmacology and Computational Insights into Celastrol-like Molecules

Antioxidant activity of soybean peptides and Keap1 protein: A combined in vitro and in silico analysis

GPT4Kinase: High-accuracy prediction of inhibitor-kinase binding affinity utilizing large language model

Specific Substrate Activity of Lotus Root Polyphenol Oxidase: Insights from Gaussian-Accelerated Molecular Dynamics and Markov State Models

Computational Insights into Reproductive Toxicity: Clustering, Mechanism Analysis, and Predictive Models

Elucidating the structural basis of vitamin B12 derivatives as novel potent inhibitors of PTP1B: Insights from inhibitory mechanisms using Gaussian accelerated molecular dynamics (GaMD) and in vitro study

Mulberry Leaf Compounds and Gut Microbiota in Alzheimer’s Disease and Diabetes: A Study Using Network Pharmacology, Molecular Dynamics Simulation, and Cellular Assays

Unveiling Anti-Diabetic Potential of Baicalin and Baicalein from Baikal Skullcap: LC–MS, In Silico, and In Vitro Studies

Exploring the anti-gout potential of sunflower receptacles alkaloids: A computational and pharmacological analysis

Study on the Mechanism of Interaction between Dipeptidyl Peptidase 4 and Inhibitory Peptides Based on Gaussian Accelerated Molecular Dynamic Simulation

Using deep learning and molecular dynamics simulations to unravel the regulation mechanism of peptides as noncompetitive inhibitor of xanthine oxidase

Interactions between Inhibitors and 5-Lipoxygenase: Insights from Gaussian Accelerated Molecular Dynamics and Markov State Models

Molecular insights into chronic atrophic gastritis treatment: Coptis chinensis Franch studied via network pharmacology, molecular dynamics simulation and experimental analysis

VmmScore: An umami peptide prediction and receptor matching program based on a deep learning approach

基于桑黄对肺炎的治疗作用及其机制的网络药理学分析

Probing the mechanisms of hydrazide-based HDAC inhibitors binding to HDAC3 using Gaussian accelerated molecular dynamics (GaMD) simulations

Network Pharmacology Combined with Machine Learning to Reveal the Action Mechanism of Licochalcone Intervention in Liver Cancer

Functionalized Fullerene Potentially Inhibits SARS-CoV-2 Infection by Modulating Spike Protein Conformational Changes

Network pharmacology and experiment indicated that medicinal food homologous components play important roles in insomnia

Investigating the Vital Role of the Identified Abietic Acid from Helianthus annuus L. Calathide Extract against Hyperuricemia via Human Embryonic Kidney 293T Cell Model

In Silico Discovery of Anticancer Peptides from Sanghuang

The Active Components of Sunflower (Helianthus annuus L.) Calathide and the Effects on Urate Nephropathy Based on COX-2/PGE2 Signaling Pathway and the Urate Transporter URAT1, ABCG2, and GLUT9

基于拉伸分子动力学模拟的黄嘌呤氧化酶抑制剂解离途径的理论研究

基于分子动力学模拟的VmoLac非特异性底物催化活性的理论研究

Chemical Compounds, Antioxidant Activities, and Inhibitory Activities Against Xanthine Oxidase of the Essential Oils From the Three Varieties of Sunflower (Helianthus annuus L.) Receptacles

Identification of Scopoletin and Chlorogenic Acid as Potential Active Components in Sunflower Calathide Enzymatically Hydrolyzed Extract towards Hyperuricemia

Molecular Dynamics Simulations Study of the Interactions between Human Dipeptidyl-Peptidase III and Two Substrates

Targeting N-Terminal Human Maltase-Glucoamylase to Unravel Possible Inhibitors Using Molecular Docking, Molecular Dynamics Simulations, and Adaptive Steered Molecular Dynamics Simulations

In silico study to predict potential precursors of human dipeptidyl peptidase-IV inhibitors from hazelnut

Protective effect of Phaeoporus obliquus polysaccharide against acute liver injury induced by carbon tetrachloride and alcohol in mice.

Conformational Changes of Glutamine 5′-Phosphoribosylpyrophosphate Amidotransferase for Two Substrates Analogue Binding: Insight from Conventional Molecular Dynamics and Accelerated Molecular Dynamics Simulations

Extraction, Radical Scavenging Activities, and Chemical Composition Identification of Flavonoids from Sunflower (Helianthus annuus L.) Receptacles

Chemical Composition and Antimicrobial and Antioxidant Activities of Essential Oil of Sunflower (Helianthus annuus L.) Receptacle

Identification of common differentially‑expressed miRNAs in ovarian cancer cells and their exosomes compared with normal ovarian surface epithelial cell cells

Knockdown of LMW-PTP enhances stress resistance in Caenorhabditis elegans

Hypoglycemic effect and mechanism of isoquercitrin as an inhibitor of dipeptidyl peptidase-4 in type 2 diabetic mice

Arbutin increases Caenorhabditis elegans longevity and stress resistance

2-SeCD treatment extends lifespan, improves healthspan and enhances resistance to stress in Caenorhabditis elegans

Identification of key genes associated with the effect of estrogen on ovarian cancer using microarray analysis

Association of ACP1 gene polymorphisms and coronary artery disease in northeast Chinese population

Magnolia officinalisExtract Contains Potent Inhibitors against PTP1B and Attenuates Hyperglycemia in db/db Mice

Expression, purification, and characterization of human osteoclastic protein-tyrosine phosphatase catalytic domain in Escherichia coli

丁香对胰岛素信号通路的影响及2型糖尿病降糖机制的研究

巨核细胞蛋白质酪氨酸磷酸酶2的克隆表达及其与骨质疏松症的关系

超高效液相色谱串联质谱联用法快速筛选3-羟基-3-甲基戊二酰辅酶A还原酶抑制剂

蛋白质酪氨酸磷酸酶SHP-1的中药抑制剂筛选

蛋白质酪氨酸磷酸酶SHP-1催化结构域的克隆表达及抑制剂筛选

蛋白质酪氨酸磷酸酶及相关疾病

人SHP-1催化结构域的克隆表达及其多克隆抗体的制备

书籍章节

Effect of Candesartan cilexetil as a sensitive and effective inhibitor of SHP-1 on insulin signaling pathway

研究方向