闵俊哲｜延边大学｜学者主页

2026

Development of a facile and novel strategy for N-glycan analysis: Stable isotope labeling via Endo‑CC N180H‑catalyzed transglycosylation for quantitative glycomics

Yuxuan Li, Songze Wang, Hang Shi, Shiqiao Cong, Mingshan Zheng, Xiling Li, Kenichiro Todoroki, Jun Zhe Min

Journal of Pharmaceutical and Biomedical Analysis

DOI

2026

Relative quantitation strategy of glycans in tocilizumab labeled based on mass spectrometry probes d0/d15-CEBTPP: Monitoring glycan changes in rat serum

Songze Wang, Shiqiao Cong, Can Ding, Xiling Li, Guangchun Piao, Jun Zhe Min

Journal of Pharmaceutical Analysis

DOI

2026

Simultaneous Determination and Enantiomeric Separation of Five DL‐Thiol Compounds Using UHPLC‐HRMS With Chiral Derivatization in Sake: Dynamic Monitoring of Human Urine After Drinking

Shuyun Xiao, Hang Shi, Shuyi Song, Jun Zhe Min

Chirality

DOI

2026

Simultaneous Separation and Determination of Chiral Amino Acids and Histamine in Doenjang by LC–MS/MS Based on a Novel Chiral Derivatization Probe Labeling

Mengwei Zhang, Shuyi Song, Yingao Wang, Songze Wang, Mingshan Zheng, X. F. Li, Jun Zhe Min

Chirality

DOI

2025

Chiral probe labeling techniques in liquid chromatography separation: Advances in chiral metabolomics analysis

Yuxuan Li, Xinyi Xu, Qian Li, Xinxin Kong, Guangyi Zhang, Jun Zhe Min

Journal of Chromatography A

DOI

2025

A novel method for the determination of dried saliva spots (DSS) based on UHPLC-MS/MS for three α-dicarbonyl compounds: An application in the saliva of diabetes patients

Guangyi Zhang, Chengqiang Han, Yuxuan Li, Xi-Ling Li, Hongmei Jin, Jun Zhe Min

Journal of Pharmaceutical and Biomedical Analysis

DOI

2025

Simultaneous chiral analysis of four DL-thiol compounds in human saliva by Ultra-high-performance liquid chromatography high-resolution mass spectrometry: Differential evaluation of oxidative stress between smokers and non-smokers

Yuxuan Li, Yuanjie Shan, Chenglong Yu, Xiling Li, Jun Zhe Min

Journal of Chromatography A

DOI

2025

Simultaneous chiral analysis of DL-asp and DL-α-HB with derivatization in human fingernail by UHPLC-MS/MS: an application in colorectal cancer

Yinshuo Xu, Yuanjie Shan, Yuta Nishio, Kenichiro Todoroki, Toshimasa Toyo’oka, Toufeng Jin, Jun Zhe Min

Journal of Chromatography B

DOI

2025

Simultaneous determination of α-dicarbonyl compounds in Chinese Korean ethnic rice wine using pre-column derivatization with UHPLC-MS/MS

Yinshuo Xu, Zai-Gang Han, Minghui Zhang, Qing Shi, Jun Zhe Min

Journal of Food Science and Technology

DOI

2024

Simultaneous determination of free DL-amino acids in human hair with a novel DBD-M-Pro derivatization by UHPLC-HRMS: An application in diabetes patients

Songze Wang, Xin Zhou, Xin Wang, Shengyu Cheng, Xiling Li, Jun Nan, Jun Zhe Min

Journal of Pharmaceutical and Biomedical Analysis

DOI

2024

A novel UHPLC-MS/MS method for the determination of three selenoamino acids in organic selenium supplements and dynamic monitoring in human urine after consumption

Xinxin Kong, Lingli Zhang, Ling Ling Cai, Shengyu Cheng, Xi-Ling Li, Toufeng Jin, Jun Zhe Min

European Food Research and Technology

DOI

2024

A dried sweat spot paper (DSSP) method based on novel mass spectrometry probe labeling for detection and resolution of DL-lactate enantiomers as potential biomarkers for diabetes mellitus

Yueying Jin, Minghui Zhang, Xiling Li, Chengqiang Han, Qing Shi, Jun Zhe Min

Analytica Chimica Acta

DOI

2024

Constituents of Chimaphila japonica and Their Diuretic Activity

Yue Yu, Deri Hu, Jinze Liu, Chenghao Wu, Yuhong Sun, Mingyue Lang, Xuan Zhuo Han, Dongzhou Kang, Jun Zhe Min, Cui Hong, Mingshan Zheng

Molecules

DOI

2024

Development of an on-site therapeutic drug monitoring method using a portable spectrometer

Kenichiro Todoroki, Nan Fukudo, Yuto Kudoh, Hajime Mizuno, Jun Zhe Min, Shimako Tanaka, Shinya Uchida, Noriyuki Namiki, Toshimasa Toyo’oka

Analytical Sciences

DOI

2024

Chemical constituents of Ulmus pumila L. and their chemotaxonomic significance

Deri Hu, Zhenyu Liu, Yue Yu, Chenghao Wu, Jinze Liu, Dongzhou Kang, Junzhe Min, Mingshan Zheng

Biochemical Systematics and Ecology

DOI

2023

A novel reagent pre-column derivatization method for UHPLC-MS/MS to determine four α-dicarbonyl compounds in beer

Zai-Gang Han, Lingli Zhang, Chao Qi, Qing Shi, Jun Zhe Min

European Food Research and Technology

DOI

2023

Development of a novel method for analysing N-acetyl-DL-leucine enantiomers in human fingernail by UPLC-ESI-MS/MS and the evaluation in diabetes mellitus

Jing Li, Xin Zhou, Takashi Morotomi, Kenichiro Todoroki, Toshimasa Toyo’oka, Qing Shi, Toufeng Jin, Jun Zhe Min

Clinica Chimica Acta

DOI

2023

Simultaneous quantification of five DL-amino acids in beer by UHPLC–MS/MS using a novel chiral mass spectrometry probe

Yan Zhu, Lei Di, Shengyu Cheng, Yueying Jin, Minghui Zhang, Lingli Zhang, Xin Wang, Xiling Li, Yu Mi Han, Chunyan Xu, Jun Zhe Min

European Food Research and Technology

DOI

2023

Development and evaluation of a novel fluorescent chiral derivatization reagent DBD-S-M-Pro: first observation of four chiral amino acids in human hair

Xin Wang, Xiaoqi Sun, Yueying Jin, Shengyu Cheng, Yu Mi Han, Minghui Zhang, Lingli Zhang, Xiling Li, Chunyan Xu, Jun Zhe Min

Analytical Methods

DOI

2022

Relative quantitation of glycans in cetuximab using ultra-high-performance liquid chromatography-high-resolution mass spectrometry by Pronase E digestion

Xiling Li, Chengqiang Han, Miao Luo, Shuyun Xiao, Jing Li, Chenglong Yu, Shengyu Cheng, Yueying Jin, Yu Mi Han, Kenichiro Todoroki, Qing Shi, Jun Zhe Min

Journal of Chromatography A

DOI

2022

A novel UHPLC-MS/MS method for the determination of four α-dicarbonyl compounds in wine and dynamic monitoring in human urine after drinking

Chao Qi, Yueying Jin, Shengyu Cheng, Lei Di, Xin Wang, Minghui Zhang, Lingli Zhang, Xi-Ling Li, Yu Mi Han, Qingkun Ma, Jun Zhe Min

Food Research International

DOI

2022

Comprehensive characterization of the chemical composition of Lurong dabu decoction and its absorbed prototypes and metabolites in rat plasma using UHPLC–Q Exactive Orbitrap–HRMS

Yueying Jin, Shengyu Cheng, Ruobai Liu, Chenglong Yu, Lingli Zhang, Xiling Li, Guanghai Yan, Mingyu Zheng, Jun Zhe Min

Food Research International

DOI

2022

Development and validation of a simple and noninvasive method for salivary uric acid: potential applications for monitoring the salivary uric acid level in healthy volunteers and gout patients

Lili Zhao, Qingkun Ma, Chunyan Xu, Guanghao Zheng, Yu Mi Han, Qing Qian, Wenlong Jin, Jun Zhe Min

Brazilian Journal of Pharmaceutical Sciences

DOI

2021

Highly sensitive novel fluorescent chiral probe possessing (S)-2-methylproline structures for the determination of chiral amino compounds by ultra-performance liquid chromatography with fluorescence: An application in the saliva of healthy volunteer

Xiling Li, Yu Mi Han, Yu‐An Huang, Xiaoqi Sun, Shuyun Xiao, Jun Zhe Min

Journal of Chromatography A

DOI

2021

Simultaneous determination of three endogenous chiral thiol compounds in serum from humans at normal and stress states using ultrahigh-performance liquid chromatography coupled to quadrupole-Orbitrap high resolution mass spectrometry

Qingkun Ma, Xiaoxi Man, Chunyan Xu, Jian Huo, Chao Qi, Qing Shi, Jun Nan, Jun Zhe Min

Journal of Chromatography A

DOI

2021

Simultaneous determination of DL-cysteine, DL-homocysteine, and glutathione in saliva and urine by UHPLC-Q-Orbitrap HRMS: Application to studies of oxidative stress

Qingkun Ma, Chao Qi, Xiling Li, Qing Shi, Chunyan Xu, Toufeng Jin, Jun Zhe Min

Journal of Pharmaceutical and Biomedical Analysis

DOI

2021

Determination of N-acetyl-DL-leucine in the saliva of healthy volunteers and diabetic patients using ultra-performance liquid chromatography with fluorescence detection

Xiling Li, Wenhao Li, Chao Qi, Lili Zhao, Wenlong Jin, Jun Zhe Min

Clinica Chimica Acta

DOI

2021

Potential use of a dried saliva spot (DSS) in therapeutic drug monitoring and disease diagnosis

Yu Mi Han, Xiling Li, Minghui Zhang, Jing Wang, Su Zeng, Jun Zhe Min

Journal of Pharmaceutical Analysis

DOI

2021

Simultaneous Determination of Chiral Thiol Compounds and Monitoring of Dynamic Changes in Human Urine after Drinking Chinese Korean Ethnic Rice Wine

Qingkun Ma, Xiling Li, Chao Qi, Minghui Zhang, Zheng Xin Yan, Qing Shi, Yueying Jin, Lei Di, Jun Nan, Jun Zhe Min

Journal of Agricultural and Food Chemistry

DOI

2021

Simultaneous Determination of Free DL-Amino Acids in Natto with Novel Fluorescent Derivatization by UPLC-FL

Yueying Jin, Chunyan Xu, Jing Wang, Xiaoxi Man, Qing Shi, Fenghuan Nie, Jun Nan, Jun Zhe Min

Food Analytical Methods

DOI

2021

A convenient sampling and noninvasive dried spot method of uric acid in human saliva: Comparison of serum uric acid value and salivary uric acid in healthy volunteers and hyperuricemia patients

Yu Mi Han, Qing Shi, Chunyan Xu, Lei Di, Lili Zhao, Wenlong Jin, Jun Zhe Min

Journal of Chromatography B

DOI

2020

益津降糖颗粒质量标准改进研究

满小溪，许春燕，高光男，杨德智，闵俊哲

《延边大学学报(自然科学版)》

DOI

2020

Fluorescence Bioanalysis of Bevacizumab Using Pre-Column and Post-Column Derivatization – Liquid Chromatography After Immunoaffinity Magnetic Purification

Kenichiro Todoroki, Tatsuki Nakano, Hideki Hayashi, Hajime Mizuno, Jun Zhe Min, Toshimasa Toyo’oka

Chromatography

DOI

2020

Urate in fingernail represents the deposition of urate burden in gout patients

Haibing Chen, Lili Zhao, Fengjing Liu, Si Chen, Zhumeng Hu, Li-Hui Chen, Yiwen Ma, Kaifeng Guo, Aichang Ji, Tony Raymond Merriman, Jun Zhe Min

Scientific Reports

DOI

2019

Evaluation of chiral separation efficiency of a novel OTPTHE derivatization reagent: Applications to liquid‐chromatographic determination of DL‐serine in human plasma

Yu Mi Han, Mei‐Na Jin, Chunyan Xu, Qing Qian, Jun Nan, Toufeng Jin, Jun Zhe Min

Chirality

DOI

2018

Sensitive and Comprehensive LC-MS/MS Analyses of Chiral Pharmaceuticals and Their Hepatic Metabolites Using Ovomucoid Column

Kenichiro Todoroki, Yuto Kudoh, Misuzu Nakamura, Yuki Shimizu, Takamitsu Sasaki, 大槻秀幸, Keisuke Wada, Jun Zhe Min, Hajime Mizuno, Kouichi Yoshinari, Toshimasa Toyo’oka

Analytical Sciences

DOI

2017

High Sensitivity and Precision High-Temperature Reversed-Phase LC Analysis of Bevacizumab for Intact Bioanalysis of Therapeutic Monoclonal Antibodies

Tomohiro Yamada, Hajime Mizuno, Jun Zhe Min, Toshimasa Toyo’oka, Kenichiro Todoroki

Chromatography

DOI

2016

Highly sensitive derivatization reagents possessing positively charged structures for the determination of oligosaccharides in glycoproteins by high-performance liquid chromatography electrospray ionization tandem mass spectrometry

Jun Zhe Min, Keisuke Nagai, Qing Shi, Wenjun Zhou, Kenichiro Todoroki, Kōichi Inoue, Yong‐Ill Lee, Toshimasa Toyo’oka

Journal of Chromatography A

DOI

2016

Uric acid quantification in fingernail of gout patients and healthy volunteers using HPLC‐UV

Xiling Li, Qing Shi, Wenlong Jin, Gao Li, Kenichiro Todoroki, Hajime Mizuno, Toshimasa Toyo’oka, Jun Zhe Min

Biomedical Chromatography

DOI

2015

Human nails metabolite analysis: A rapid and simple method for quantification of uric acid in human fingernail by high-performance liquid chromatography with UV-detection

Xiling Li, Gao Li, Ying‐Zi Jiang, Dongzhou Kang, Cheng Hua Jin, Qing Shi, Toufeng Jin, Kōichi Inoue, Kenichiro Todoroki, Toshimasa Toyo’oka, Jun Zhe Min

Journal of Chromatography B

DOI

2015

First observation of N-acetyl leucine and N-acetyl isoleucine in diabetic patient hair and quantitative analysis by UPLC–ESI–MS/MS

Jun Zhe Min, Yuki Tomiyasu, Takashi Morotomi, Ying‐Zi Jiang, Gao Li, Qing Shi, Hai‐fu Yu, Kōichi Inoue, Kenichiro Todoroki, Toshimasa Toyo’oka

Clinica Chimica Acta

DOI

2014

Development of the High Sensitive Separation Analysis Method of Metabolites in Human Nail and its Application to the Diagnosis of Chronic Disease

Jun Zhe Min

Chromatography

DOI

2014

Rapid and Sensitive Determination of Diacetylpolyamines in Human Fingernail by Ultraperformance Liquid Chromatography Coupled with Electrospray Ionization Tandem Mass Spectrometry

Jun Zhe Min, Yuka Morota, Ying‐Zi Jiang, Gao Li, Dongri Jin, Dongzhou Kang, Hai‐fu Yu, Kōichi Inoue, Kenichiro Todoroki, Toshimasa Toyo’oka

European Journal of Mass Spectrometry

DOI

2014

Development of a Highly Sensitive Separation Method for the Analysis of Metabolites in Human Nails and Applications in the Diagnosis of Chronic Disease

Jun Zhe Min

YAKUGAKU ZASSHI

DOI

2013

A quantitative analysis of the polyamine in lung cancer patient fingernails by LC‐ESI‐MS/MS

Jun Zhe Min, Akihito Matsumoto, Li Gao, Ying‐Zi Jiang, Hai‐fu Yu, Kenichiro Todoroki, Kōichi Inoue, Toshimasa Toyo’oka

Biomedical Chromatography

DOI

精选作品

期刊论文

Development of a facile and novel strategy for N-glycan analysis: Stable isotope labeling via Endo‑CC N180H‑catalyzed transglycosylation for quantitative glycomics

Relative quantitation strategy of glycans in tocilizumab labeled based on mass spectrometry probes d0/d15-CEBTPP: Monitoring glycan changes in rat serum

Simultaneous Determination and Enantiomeric Separation of Five DL‐Thiol Compounds Using UHPLC‐HRMS With Chiral Derivatization in Sake: Dynamic Monitoring of Human Urine After Drinking

Simultaneous Separation and Determination of Chiral Amino Acids and Histamine in Doenjang by LC–MS/MS Based on a Novel Chiral Derivatization Probe Labeling

Chiral probe labeling techniques in liquid chromatography separation: Advances in chiral metabolomics analysis

A novel method for the determination of dried saliva spots (DSS) based on UHPLC-MS/MS for three α-dicarbonyl compounds: An application in the saliva of diabetes patients

Simultaneous chiral analysis of four DL-thiol compounds in human saliva by Ultra-high-performance liquid chromatography high-resolution mass spectrometry: Differential evaluation of oxidative stress between smokers and non-smokers

Simultaneous chiral analysis of DL-asp and DL-α-HB with derivatization in human fingernail by UHPLC-MS/MS: an application in colorectal cancer

Simultaneous determination of α-dicarbonyl compounds in Chinese Korean ethnic rice wine using pre-column derivatization with UHPLC-MS/MS

Simultaneous determination of free DL-amino acids in human hair with a novel DBD-M-Pro derivatization by UHPLC-HRMS: An application in diabetes patients

A novel UHPLC-MS/MS method for the determination of three selenoamino acids in organic selenium supplements and dynamic monitoring in human urine after consumption

A dried sweat spot paper (DSSP) method based on novel mass spectrometry probe labeling for detection and resolution of DL-lactate enantiomers as potential biomarkers for diabetes mellitus

Constituents of Chimaphila japonica and Their Diuretic Activity

Development of an on-site therapeutic drug monitoring method using a portable spectrometer

Chemical constituents of Ulmus pumila L. and their chemotaxonomic significance

A novel reagent pre-column derivatization method for UHPLC-MS/MS to determine four α-dicarbonyl compounds in beer

Development of a novel method for analysing N-acetyl-DL-leucine enantiomers in human fingernail by UPLC-ESI-MS/MS and the evaluation in diabetes mellitus

Simultaneous quantification of five DL-amino acids in beer by UHPLC–MS/MS using a novel chiral mass spectrometry probe

Development and evaluation of a novel fluorescent chiral derivatization reagent DBD-S-M-Pro: first observation of four chiral amino acids in human hair

Relative quantitation of glycans in cetuximab using ultra-high-performance liquid chromatography-high-resolution mass spectrometry by Pronase E digestion

A novel UHPLC-MS/MS method for the determination of four α-dicarbonyl compounds in wine and dynamic monitoring in human urine after drinking

Comprehensive characterization of the chemical composition of Lurong dabu decoction and its absorbed prototypes and metabolites in rat plasma using UHPLC–Q Exactive Orbitrap–HRMS

Development and validation of a simple and noninvasive method for salivary uric acid: potential applications for monitoring the salivary uric acid level in healthy volunteers and gout patients

Highly sensitive novel fluorescent chiral probe possessing (S)-2-methylproline structures for the determination of chiral amino compounds by ultra-performance liquid chromatography with fluorescence: An application in the saliva of healthy volunteer

Simultaneous determination of three endogenous chiral thiol compounds in serum from humans at normal and stress states using ultrahigh-performance liquid chromatography coupled to quadrupole-Orbitrap high resolution mass spectrometry

Simultaneous determination of DL-cysteine, DL-homocysteine, and glutathione in saliva and urine by UHPLC-Q-Orbitrap HRMS: Application to studies of oxidative stress

Determination of N-acetyl-DL-leucine in the saliva of healthy volunteers and diabetic patients using ultra-performance liquid chromatography with fluorescence detection

Potential use of a dried saliva spot (DSS) in therapeutic drug monitoring and disease diagnosis

Simultaneous Determination of Chiral Thiol Compounds and Monitoring of Dynamic Changes in Human Urine after Drinking Chinese Korean Ethnic Rice Wine

Simultaneous Determination of Free DL-Amino Acids in Natto with Novel Fluorescent Derivatization by UPLC-FL

A convenient sampling and noninvasive dried spot method of uric acid in human saliva: Comparison of serum uric acid value and salivary uric acid in healthy volunteers and hyperuricemia patients

益津降糖颗粒质量标准改进研究

Fluorescence Bioanalysis of Bevacizumab Using Pre-Column and Post-Column Derivatization – Liquid Chromatography After Immunoaffinity Magnetic Purification

Urate in fingernail represents the deposition of urate burden in gout patients

Evaluation of chiral separation efficiency of a novel OTPTHE derivatization reagent: Applications to liquid‐chromatographic determination of DL‐serine in human plasma

Sensitive and Comprehensive LC-MS/MS Analyses of Chiral Pharmaceuticals and Their Hepatic Metabolites Using Ovomucoid Column

High Sensitivity and Precision High-Temperature Reversed-Phase LC Analysis of Bevacizumab for Intact Bioanalysis of Therapeutic Monoclonal Antibodies

Highly sensitive derivatization reagents possessing positively charged structures for the determination of oligosaccharides in glycoproteins by high-performance liquid chromatography electrospray ionization tandem mass spectrometry

Uric acid quantification in fingernail of gout patients and healthy volunteers using HPLC‐UV

Human nails metabolite analysis: A rapid and simple method for quantification of uric acid in human fingernail by high-performance liquid chromatography with UV-detection

First observation of N-acetyl leucine and N-acetyl isoleucine in diabetic patient hair and quantitative analysis by UPLC–ESI–MS/MS

Development of the High Sensitive Separation Analysis Method of Metabolites in Human Nail and its Application to the Diagnosis of Chronic Disease

Rapid and Sensitive Determination of Diacetylpolyamines in Human Fingernail by Ultraperformance Liquid Chromatography Coupled with Electrospray Ionization Tandem Mass Spectrometry

Development of a Highly Sensitive Separation Method for the Analysis of Metabolites in Human Nails and Applications in the Diagnosis of Chronic Disease

A quantitative analysis of the polyamine in lung cancer patient fingernails by LC‐ESI‐MS/MS

会议论文

氨基官能团标记荧光手性衍生化试剂DBD-M-Pro的开发

丙半胱氨酸结构质谱手性衍生化试剂的开发

基于突变酶Endo-M-N175的糖链相对定量

人体唾液中尿酸定量新方法的研究

新型巯基化合物手性拆分衍生化试剂的开发

柱前衍生UPLC-FL法对胶原蛋白中氨基酸光学异构体的组成分析

氨基手性代谢物标记带正电荷硫代脯氨酸结构新型手性质谱试剂的开发

吡咯烷结构新型羧基衍生化手性质谱试剂的开发及效能评价

大肠癌患者手指甲中手性代谢物的分析

预印本

Advances in Analytical Methods for Chiral Separation and Determination of Thiol Enantiomers in Biological Specimens

研究方向