孟安明｜清华大学｜学者主页

2026

Sclerotomal hematopoiesis in vertebrate embryos contributes to robustness of the blood system

Zheng Jiang, Tianqi Li, Yixiao Song, Luxi Chen, Juhui Qiu, Fan Zhou, Xiaotong Wu, Jianbin Wang, Anming Meng

National Science Review

DOI

2026

Maternal Huluwa regulates postfertilization microtubule array organization for asymmetrical transport of dorsal determinants in zebrafish

Xin Liu, Fangjie Cao, Yaqi Li, Tursunjan Aziz, Tong Lv, Jing Chen, Xiaotong Wu, Anming Meng

Nature Communications

DOI

2026

PGC-derived migrasomes couple PGC proliferation with migration

Boqi Liu, Zheng Jiang, Wenhao Song, Zhaocheng Zhai, Yaqi Li, Weiying Zhang, Anming Meng, Li Yu

Nature Communications

DOI

2026

BMP–Smad1/9 signaling plays a critical role in regulating zebrafish PGC proliferation

Tao Zheng, Yaqi Li, Guangyuan Li, Zihang Wei, Jie Li, Zheng Jiang, Roshan Shah, Weiying Zhang, Cencan Xing, Anming Meng, Xiaotong Wu

Nature Communications

DOI

2025

Stage- and tissue-specific gene editing using 4-OHT–inducible Cas9 in whole organism

Yaqi Li, Weiying Zhang, Zihang Wei, Han Li, Xin Liu, Tao Zheng, Tursunjan Aziz, Cencan Xing, Anming Meng, Xiaotong Wu

The Journal of Cell Biology

DOI

2025

Maternal control of embryonic dorsal organizer in vertebrates

Jing Chen, Anming Meng

Cells and Development

DOI

2024

Znf706 regulates germ plasm assembly and primordial germ cell development in zebrafish

Weiying Zhang, Yaqi Li, Li Han, Xin Liu, Tao Zheng, Guangyuan Li, Boqi Liu, Tong Lv, Zihang Wei, Cencan Xing, Shunji Jia, Anming Meng, Xiaotong Wu

Journal of genetics and genomics/Journal of Genetics and Genomics

DOI

2024

Aagab is required for zebrafish larval development by regulating neural activity

Shihui Ding, Tursunjan Aziz, Anming Meng, Shunji Jia

Journal of genetics and genomics/Journal of Genetics and Genomics

DOI

2024

A Huluwa phosphorylation switch regulates embryonic axis induction

Yao Li, Yun Yan, Bo Gong, Qianwen Zheng, Hai-Yan Zhou, Jiarui Sun, Mingpeng Li, Zhao Wang, Yaohui Li, Yunjing Wan, Weixi Chen, Shiqian Qi, Xianming Mo, Anming Meng, Bo Xiang, Jing Chen

Nature Communications

DOI

2024

Mapping the chromatin accessibility landscape of zebrafish embryogenesis at single-cell resolution by SPATAC-seq

Keyong Sun, Xin Liu, Runda Xu, Chang Liu, Anming Meng, Xun Lan

Nature Cell Biology

DOI

2024

GPI transamidase complex is required for primordial germ cell migration and development in zebrafish

Weiying Zhang, Yaqi Li, Jing Chen, Likun Yao, Bingjie Zhang, Linbo Zhang, Boqi Liu, Weimin Shen, Anming Meng, Xiaotong Wu

Journal of Molecular Cell Biology

DOI

2024

ULI-ssDRIP-seq revealed R-loop dynamics during vertebrate early embryogenesis

Wei Min Xu, Xin Liu, Jinjin Li, Changbin Sun, Luxi Chen, Jincong Zhou, Kuan Li, Qin Li, Anming Meng, Qianwen Sun

Cell Insight

DOI

2023

Temporospatial inhibition of Erk signaling is required for lymphatic valve formation

Yaping Meng, Tong Lv, Junfeng Zhang, Weimin Shen, Lifang Li, Yaqi Li, Xin Liu, Xing Lei, Xuguang Lin, Hanfang Xu, Anming Meng, Shunji Jia

Signal Transduction and Targeted Therapy

DOI

2022

The second polar body contributes to the fate asymmetry in the mouse embryo

Hongbin Jin, Han Na Yang, Huasong Wang, John Xiao He Li, Weimin Shen, Lin Zhang, Luxi Chen, Shunji Jia, Ping Yuan, Hui Chen, Anming Meng

National Science Review

DOI

2022

Comprehensive maturity of nuclear pore complexes regulates zygotic genome activation

Weimin Shen, Bo Gong, Cencan Xing, Lin Zhang, Jiawei Sun, Yuling Chen, Changmei Yang, Lu Yan, Luxi Chen, Likun Yao, Guangyuan Li, Haiteng Deng, Xiaotong Wu, Anming Meng

Cell

DOI

2022

Regulatory factor identification for nodal genes in zebrafish by causal inference

Cencan Xing, Zehua Zeng, Yaqi Li, Bo Gong, Weimin Shen, Roshan Shah, Lu Yan, Hongwu Du, Anming Meng

Frontiers in Cell and Developmental Biology

DOI

2022

Maternal Factors and Nodal Autoregulation Orchestrate Nodal Gene Expression for Embryonic Mesendoderm Induction in the Zebrafish

Cencan Xing, Weimin Shen, Bo Gong, Yaqi Li, Lu Yan, Anming Meng

Frontiers in Cell and Developmental Biology

DOI

2021

The rise of developmental biology in China

Xun Huang, Xinhua Lin, Feng Liu, Gen Wu, Zhongzhou Yang, Anming Meng

Development Growth & Differentiation

DOI

2021

TGFβ family signaling and development

Shunji Jia, Anming Meng

Development

DOI

2021

5′ Half of specific tRNAs feeds back to promote corresponding tRNA gene transcription in vertebrate embryos

Luxi Chen, Wei Min Xu, Kunpeng Liu, Zheng Jiang, Han Na Yang, Hongbin Jin, Lin Zhang, Weimin Shen, Shunji Jia, Qianwen Sun, Anming Meng

Science Advances

DOI

2021

Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs

Xiaotong Wu, Hongmei Zhang, Bingjie Zhang, Yu Zhang, Qiu-Wen Wang, Weimin Shen, Xi Wu, Lijia Li, Weikun Xia, Ryohei Nakamura, Bo-Feng Liu, Feng Liu, H. Takeda, Anming Meng, Wei Xie

bioRxiv

DOI

2019

Migrasomes provide regional cues for organ morphogenesis during zebrafish gastrulation

Dong Jiang, Zheng Jiang, Di Lu, Xuan Wang, Haisha Liang, Junfeng Zhang, Yaping Meng, Ying Li, Danni Wu, Yuwei Huang, Yuling Chen, Haiteng Deng, Qing Wu, Jing‐Wei Xiong, Anming Meng, Li Yu

Nature Cell Biology

DOI

2019

Sec14l3 potentiates VEGFR2 signaling to regulate zebrafish vasculogenesis

Bo Gong, Zhihao Li, Wanghua Xiao, Guangyuan Li, Shihui Ding, Anming Meng, Shunji Jia

Nature Communications

DOI

2019

RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay

Ying Yang, Lu Wang, Lu Wang, Xiao Han, Wen-Lan Yang, Mengmeng Zhang, Haili Ma, Baofa Sun, Ang Li, Jun Xia, Jing Chen, Jian Heng, Baixing Wu, Yusheng Chen, Jiawei Xu, Xin Yang, Huan Yao, Jiawei Sun, Cong Lyu, Hai-Lin Wang, Ying Huang, Yingpu Sun, Yongliang Zhao, Anming Meng, Jinbiao Ma, Feng Liu, Yun‐Gui Yang, Yun‐Gui Yang

Molecular Cell

DOI

2018

prpf4 is essential for cell survival and posterior lateral line primordium migration in zebrafish

Yixia Wang, Yanchao Han, Peng‐Fei Xu, Shihui Ding, Guangyuan Li, Hongbin Jin, Yaping Meng, Anming Meng, Shunji Jia

Journal of genetics and genomics/Journal of Genetics and Genomics

DOI

2018

Maternal Huluwa dictates the embryonic body axis through β-catenin in vertebrates

Lu Yan, Jing Chen, Xuechen Zhu, Jiawei Sun, Xiaotong Wu, Weimin Shen, Weiying Zhang, Qinghua Tao, Anming Meng

Science

DOI

2018

Maternal Ybx1 safeguards zebrafish oocyte maturation and maternal-to-zygotic transition by repressing global translation

Jiawei Sun, Lu Yan, Weimin Shen, Anming Meng

Development

DOI

2018

Widespread Enhancer Dememorization and Promoter Priming during Parental-to-Zygotic Transition

Bingjie Zhang, Xiaotong Wu, Wenhao Zhang, Weimin Shen, Qingrui Sun, Kai‐Li Liu, Yu Zhang, Qiujun Wang, Yuanyuan Li, Anming Meng, Wei Xie

Molecular Cell

DOI

2018

The genetic program of oocytes can be modifiedin vivoin the zebrafish ovary

Xiaotong Wu, Weimin Shen, Bingjie Zhang, Anming Meng

Journal of Molecular Cell Biology

DOI

2018

Migrosome and migrocytosis

Li Yu, Dong Xiang Jiang, Zheng Jiang, Anming Meng

The FASEB Journal

DOI

2017

Nodal/Smad2靶基因的系统鉴定及其在早期胚胎发育中的功能机制

宁国柱，孟安明，王强

《生命科学》

2017

The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis

Qian Gao, Junfeng Zhang, Xiumei Wang, Ying Min Liu, Rongqiao He, Xingfeng Liu, Fei Wang, Jing Feng, Dongling Yang, Zhaoqing Wang, Anming Meng, Xiyun Yan

Nature Communications

DOI

2017

Hulu, a novel transmembrane protein, is absolutely required for organizer and body axis formation in zebrafish

Lu Yan, Jing Chen, Qinghua Tao, Anming Meng

Mechanisms of Development

DOI

2017

Comparative profiling of maternal transcriptomes in nonsense and frameshift eomesa mutants in zebrafish

Weimin Shen, Peng‐Fei Xu, Anming Meng

Mechanisms of Development

DOI

2017

The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling

Bo Gong, Weimin Shen, Wanghua Xiao, Yaping Meng, Anming Meng, Shunji Jia

eLife

DOI

2017

Author response: The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling

Bo Gong, Weimin Shen, Wanghua Xiao, Yaping Meng, Anming Meng, Shunji Jia

DOI

2017

Alkbh4 and Atrn Act Maternally to Regulate Zebrafish Epiboly

Qingrui Sun, Xingfeng Liu, Bo Gong, Di Wu, Anming Meng, Shunji Jia

International Journal of Biological Sciences

DOI

2016

The rising zebrafish research in China: Meeting report of the 3rd Chinese Zebrafish Principal Investigator Meeting & the Inaugural Meeting of China Zebrafish Society

Dongyuan Ma, Yuanyuan Xue, Yifan Zhang, Yonghua Sun, Anming Meng, Feng Liu

Journal of genetics and genomics/Journal of Genetics and Genomics

DOI

2016

Allelic reprogramming of the histone modification H3K4me3 in early mammalian development

Bingjie Zhang, Hui Zheng, Bo Huang, Wenzhi Li, Yunlong Xiang, Peng Xu, Jia Ming, Xiaotong Wu, Yu Zhang, Qianhua Xu, Wenqiang Liu, Xiaochen Kou, Yanhong Zhao, Wenteng He, Chong Li, Bo Chen, Yuanyuan Li, Qiujun Wang, Jing Ma, Qiangzong Yin, Kehkooi Kee, Anming Meng, Shaorong Gao, Feng Xu, Jie Na, Wei Xie

Nature

DOI

2016

Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation

Zhaoting Liu, Guozhu Ning, Ran-Ran XU, Yu Cao, Anming Meng, Qiang Wang

Nature Communications

DOI

2016

Eph-ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizer

Junfeng Zhang, Zheng Jiang, Xingfeng Liu, Anming Meng

Development

DOI

2016

Impairment of Cargo Transportation Caused by gbf1 Mutation Disrupts Vascular Integrity and Causes Hemorrhage in Zebrafish Embryos

Jing Chen, Xiaotong Wu, Likun Yao, Lu Yan, Lin Zhang, Juhui Qiu, Xingfeng Liu, Shunji Jia, Anming Meng

Journal of Biological Chemistry

DOI

2016

Embryonic hematopoiesis in vertebrate somites gives rise to definitive hematopoietic stem cells

Juhui Qiu, Xiaoying Fan, Yixia Wang, Hongbin Jin, Yixiao Song, Han Na Yang, Shenghong Huang, Yaping Meng, Fuchou Tang, Anming Meng

Journal of Molecular Cell Biology

DOI

2016

PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling.

Xia Lin, Xue-Yan Duan, Yao-Yun Liang, Ying Su, Katharine H. Wrighton, J. Long, Min Hu, Candi M. Davis, Jinrong Wang, F. Brunicardi, Yi-Gong Shi, Ye-Guang Chen, Anming Meng, Xin-Hua Feng

Cell

DOI

2016

Coordinate involvement of Nodal-dependent inhibition and Wnt-dependent activation in the maintenance of organizer-specific bmp2b in zebrafish.

Yu Xue, Cen-Can Xing, Wen-Juan Zhang, Canbin Chen, Jing-Jin Xu, Anming Meng, Yu-Tian Pan

International Journal of Developmental Biology

DOI

2015

The Kinase Activity-deficient Isoform of the Protein Araf Antagonizes Ras/Mitogen-activated Protein Kinase (Ras/MAPK) Signaling in the Zebrafish Embryo

Cong Xiong, Xingfeng Liu, Anming Meng

Journal of Biological Chemistry

DOI

2015

The Chromatin Remodeling Protein Bptf Promotes Posterior Neuroectodermal Fate by Enhancing Smad2-Activated wnt8a Expression

Yuanqing Ma, Xiuli Liu, Zhaoting Liu, Shi Wei, Hanqiao Shang, Yu Xue, Yu Cao, Anming Meng, Qiang Wang

Journal of Neuroscience

DOI

2015

TGFβ1a regulates zebrafish posterior lateral line formation via Smad5 mediated pathway

Cencan Xing, Bo Gong, Yu Xue, Yanchao Han, Yixia Wang, Anming Meng, Shunji Jia

Journal of Molecular Cell Biology

DOI

2014

斑马鱼母源因子在胚胎发育中的作用

胥鹏飞，孟安明

《中国科学:生命科学》

2014

Inhibition of endothelial ERK signalling by Smad1/5 is essential for haematopoietic stem cell emergence

Chunxia Zhang, Junhua Lv, Qiuping He, Sifeng Wang, Ya Gao, Anming Meng, Xiao Yi Yang, Feng Liu

Nature Communications

DOI

2014

Organizer-derived Bmp2 is required for the formation of a correct Bmp activity gradient during embryonic development

Yu Xue, Xiu-Deng Zheng, Lei Huang, Pengfei Xu, Yuanqing Ma, Zheying Min, Qinghua Tao, Yi Tao, Anming Meng

Nature Communications

DOI

2014

Destabilizing LSD1 by Jade-2 Promotes Neurogenesis: An Antibraking System in Neural Development

Xiao Han, Bin Gui, Cong Xiong, Linnan Zhao, Jing Liang, Luyang Sun, Xiaohan Yang, Wenhua Yu, Wenzhe Si, Ruorong Yan, Xia Yi, Di Zhang, Wanjin Li, Lifang Li, Jianguo Yang, Yan Wang, Yi Eve Sun, Dai Zhang, Anming Meng, Yongfeng Shang

Molecular Cell

DOI

2014

Maternal Eomesodermin regulates zygotic nodal gene expression for mesendoderm induction in zebrafish embryos

Pengfei Xu, Gaoyang Zhu, Yixia Wang, Jiawei Sun, Xingfeng Liu, Ye‐Guang Chen, Anming Meng

Journal of Molecular Cell Biology

DOI

2014

Faculty Opinions recommendation of Construction of a vertebrate embryo from two opposing morphogen gradients.

Anming Meng

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature

DOI

2014

Uracil-DNA Glycosylase Is Involved in DNA Demethylation and Required for Embryonic Development in the Zebrafish Embryo

Di Wu, Luxi Chen, Qingrui Sun, Xiaotong Wu, Shunji Jia, Anming Meng

Journal of Biological Chemistry

DOI

2014

Maternal Factors Regulate Embryonic Development in Zebrafish

Pengfei Xu, Anming Meng

DOI

2013

MicroRNA-92a Upholds Bmp Signaling by Targeting noggin3 during Pharyngeal Cartilage Formation

Guozhu Ning, Xiuli Liu, Miaomiao Dai, Anming Meng, Qiang Wang

Developmental Cell

DOI

2013

Araf kinase antagonizes Nodal-Smad2 activity in mesendoderm development by directly phosphorylating the Smad2 linker region

Xingfeng Liu, Cong Xiong, Shunji Jia, Yu Zhang, Ye‐Guang Chen, Qiang Wang, Anming Meng

Nature Communications

DOI

2013

Faculty Opinions recommendation of A molecular base for cell sorting at embryonic boundaries: contact inhibition of cadherin adhesion by ephrin/ Eph-dependent contractility.

Anming Meng

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature

DOI

2012

中国斑马鱼研究发展历程及现状

贾顺姬，孟安明

《遗传》

2012

Protein Phosphatase 4 Cooperates with Smads to Promote BMP Signaling in Dorsoventral Patterning of Zebrafish Embryos

Shunji Jia, Fangyan Dai, Di Wu, Xia Lin, Cencan Xing, Yu Xue, Ying Wang, Mu Xiao, Wei Wu, Xin‐Hua Feng, Anming Meng

Developmental Cell

DOI

2012

β-Catenin 1 and β-catenin 2 play similar and distinct roles in left-right asymmetric development of zebrafish embryos

Min Zhang, Junfeng Zhang, Sheng‐Cai Lin, Anming Meng

Development

DOI

2012

Midbrain-hindbrain boundary patterning and morphogenesis are regulated by diverse grainy head-like 2-dependent pathways

Sebastian Dworkin, Charbel Darido, Smitha Rose Georgy, Tomasz Wilanowski, Seema Srivastava, Felix E. Ellett, Luke B. Pase, Yanchao Han, Anming Meng, Joan K. Heath, Graham John Lieschke, Stephen M. Jane

Development

DOI

2012

Loss of Zygotic NUP107 Protein Causes Missing of Pharyngeal Skeleton and Other Tissue Defects with Impaired Nuclear Pore Function in Zebrafish Embryos

Xiaofeng Zheng, Shuyan Yang, Yanchao Han, Xinyi Zhao, Long Zhao, Tian Tian, Jingyuan Tong, Pengfei Xu, Cong Xiong, Anming Meng

Journal of Biological Chemistry

DOI

2012

The Tiny Zebrafish Keep Swimming Fast in the Developmental Biology Pond

Jinrong Peng, Jian Zhang, Anming Meng

Journal of genetics and genomics/Journal of Genetics and Genomics

DOI

2012

MicroRNA-206 Regulates Cell Movements during Zebrafish Gastrulation by Targeting prickle1a and Regulating c-Jun N-Terminal Kinase 2 Phosphorylation

Xiuli Liu, Guozhu Ning, Anming Meng, Qiang Wang

Molecular and Cellular Biology

DOI

2012

The Amotl2 Gene Inhibits Wnt/β-Catenin Signaling and Regulates Embryonic Development in Zebrafish

Zhiqiang Li, Yeqi Wang, Min Zhang, Peng‐Fei Xu, Huizhe Huang, Di Wu, Anming Meng

Journal of Biological Chemistry

DOI

2012

Genomic organization and expression in E. coli of Zebrafish terra

Zhixing Zhao, Zhengchun Hua, Anming Meng

TSpace (University of Toronto)

2011

Angiomotin-like2 Gene (amotl2) Is Required for Migration and Proliferation of Endothelial Cells during Angiogenesis

Yeqi Wang, Zhiqiang Li, Pengfei Xu, Lei Huang, Jingyuan Tong, Huizhe Huang, Anming Meng

Journal of Biological Chemistry

DOI

2011

Global Identification of SMAD2 Target Genes Reveals a Role for Multiple Co-regulatory Factors in Zebrafish Early Gastrulas

Zhaoting Liu, Xiwen Lin, Zhaoping Cai, Zhuqiang Zhang, Chunsheng Han, Shunji Jia, Anming Meng, Qiang Wang

Journal of Biological Chemistry

DOI

2011

SCFFBXL15 regulates BMP signalling by directing the degradation of HECT‐type ubiquitin ligase Smurf1

Yu Cui, Shan He, Cen-Can Xing, Ke-Feng Lu, Jian Wang, G. Xing, Anming Meng, Shun-Ji Jia, F. He, Lingqiang Zhang

DOI

2011

Transmembrane Protein 198 Promotes LRP6 Phosphorylation and Wnt Signaling Activation

Juan Boo Liang, Yu Fu, Cristina‐Maria Cruciat, Shunji Jia, Ying Wang, Zhen Tong, Qinghua Tao, Dierk Ingelfinger, Michael Boutros, Anming Meng, Christof Niehrs, Wei Wu

Molecular and Cellular Biology

DOI

2010

Interruption of cenph Causes Mitotic Failure and Embryonic Death, and Its Haploinsufficiency Suppresses Cancer in Zebrafish

Xinyi Zhao, Long Zhao, Tian Tian, Yu Zhang, Jingyuan Tong, Xiaofeng Zheng, Anming Meng

Journal of Biological Chemistry

DOI

2009

S21-02. Regulation of TGF-beta signalling by Dapper2 in vertebrate development

Anming Meng

Mechanisms of Development

DOI

2009

Smad2/3 activities are required for induction and patterning of the neuroectoderm in zebrafish

Shunji Jia, Di Wu, Cencan Xing, Anming Meng

Developmental Biology

DOI

2009

Rock2 controls TGFβ signaling and inhibits mesoderm induction in zebrafish embryos

Yu Zhang, Xiang Li, Jingjing Qi, Jialu Wang, Xingfeng Liu, Haiwen Zhang, Sheng‐Cai Lin, Anming Meng

Journal of Cell Science

DOI

2009

Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos

Xiang Li, Shunji Jia, Shaohe Wang, Yuemeng Wang, Anming Meng

Blood

DOI

2009

A zebrafish gene trap line expresses GFP recapturing expression pattern of foxj1b

Tian Tian, Long Zhao, Xinyi Zhao, Min Zhang, Anming Meng

Journal of genetics and genomics/Journal of Genetics and Genomics

DOI

2009

Both foxj1a and foxj1b are implicated in left–right asymmetric development in zebrafish embryos

Tian Tian, Long Zhao, Min Zhang, Xinyi Zhao, Anming Meng

Biochemical and Biophysical Research Communications

DOI

2008

Polycomb家族基因Nspc1在斑马鱼早期发育的表达

吴旭东，张敏，龚燕华，强伯勤，袁建刚，孟安明，彭小忠

《中国医学科学院学报》

2008

Heart-specific isoform of tropomyosin4 is essential for heartbeat in zebrafish embryos

Long Zhao, Xinyi Zhao, Tian Tian, Quanlong Lü, Nirma Skrbo-Larssen, Di Wu, Zheng Kuang, Xiaofeng Zheng, Yanchao Han, Shuyan Yang, Chuanmao Zhang, Anming Meng

Cardiovascular Research

DOI

2008

Protein Encoded by the Axin Allele Effectively Down-regulates Wnt Signaling but Exerts a Dominant Negative Effect on c-Jun N-terminal Kinase Signaling

Zailian Lu, Wei Liu, Huizhe Huang, Ying He, Ying Han, Yan‐Ning Rui, Yanhai Wang, Qinxi Li, Ka Ruan, Zhiyun Ye, Boon Chuan Low, Anming Meng, Sheng‐Cai Lin

Journal of Biological Chemistry

DOI

2008

Migratory Localization of Cyclin D2-Cdk4 Complex Suggests a Spatial Regulation of the G1-S Transition

Zizhang Wang, Yongli Xie, Lixia Zhang, Haiwen Zhang, Xiaojing An, Tai Wang, Anming Meng

Cell Structure and Function

DOI

2008

Dapper1 Is a Nucleocytoplasmic Shuttling Protein That Negatively Modulates Wnt Signaling in the Nucleus

Xia Gao, Jun Wen, Long Zhang, Xiang Li, Yuanheng Ning, Anming Meng, Ye‐Guang Chen

Journal of Biological Chemistry

DOI

2007

斑马鱼胚胎中受Nodal信号调控基因的鉴定

孙智慧，孟安明

《生物化学与生物物理进展》

2007

利用功能基因组学方法研究SMAD去磷酸化-TGF-β超家族信号转导的终止机制(英文)

林侠，陈晔光，孟安明，冯新华

Journal of Genetics and Genomics

2007

smad2 and smad3 Are Required for Mesendoderm Induction by Transforming Growth Factor-β/Nodal Signals in Zebrafish

Shunji Jia, Zhen Ren, Xiang Li, Ying Zheng, Anming Meng

Journal of Biological Chemistry

DOI

2007

Smad7 Antagonizes Transforming Growth Factor β Signaling in the Nucleus by Interfering with Functional Smad-DNA Complex Formation

Suping Zhang, Teng Fei, Lixia Zhang, Ran Zhang, Feng Chen, Yuanheng Ning, Yuna Han, Xin‐Hua Feng, Anming Meng, Ye‐Guang Chen

Molecular and Cellular Biology

DOI

2007

Termination of TGF-β Superfamily Signaling Through SMAD Dephosphorylation—A Functional Genomic View

Xia Lin, Ye‐Guang Chen, Anming Meng, Xin‐Hua Feng

Journal of genetics and genomics/Journal of Genetics and Genomics

DOI

2007

A β-Catenin-Independent Dorsalization Pathway Activated by Axin/JNK Signaling and Antagonized by Aida

Yan‐Ning Rui, Zhen Xu, Bo Xiong, Ying Cao, Sheng‐Cai Lin, Sheng‐Cai Lin, Min Zhang, Siu-Chiu Chan, Wen Luo, Ying Han, Zhiyun Ye, Zhiyun Ye, Hai‐Meng ZHOU, Jiahuai Han, Anming Meng, Sheng‐Cai Lin, Sheng‐Cai Lin

Developmental Cell

DOI

2007

The role of survivin in angiogenesis during zebrafish embryonic development

Alvin CH Ma, Rachel Lin, Po Kwok Chan, Joseph C.K. Leung, Loretta Y.Y. Chan, Anming Meng, Catherine M. Verfaillie, Raymond H. S. Liang, Anskar YH Leung

BMC Developmental Biology

DOI

2007

Tob genes in development and homeostasis

Shunji Jia, Anming Meng

Developmental Dynamics

DOI

2007

Amotl2 is essential for cell movements in zebrafish embryo and regulates c-Src translocation

Huizhe Huang, Fu‐I Lu, Shunji Jia, Shu Meng, Ying Cao, Yeqi Wang, Weiping Ma, Kun Yin, Zilong Wen, Jinrong Peng, Christine Thisse, Bernard Thisse, Anming Meng

Development

DOI

2006

利用模式动物探讨出生缺陷的发生机理

贾顺姬，孟安明

《生命科学》

2006

斑马鱼:在生命科学中畅游

孙智慧，贾顺姬，孟安明

《生命科学》

2006

The evolutionally conserved activity of Dapper2 in antagonizing TGF‐ß signaling

Ying Su, Long Zhang, Xia Gao, Fanwei Meng, Jun Wen, Hu Zhou, Anming Meng, Ye‐Guang Chen

The FASEB Journal

DOI

2006

The Role of Survivin in Angiogenesis during Zebrafish Embryonic Development.

Anskar Y.H. Leung, Alvin C.H. Ma, Anming Meng, Catherine M. Verfaillie, Raymond H. S. Liang

Blood

DOI

2006

Activation and roles of ALK4/ALK7-mediated maternal TGFβ signals in zebrafish embryo

Zhihui Sun, Peng Jin, Tian Tian, Yi Gu, Ye‐Guang Chen, Anming Meng

Biochemical and Biophysical Research Communications

DOI

2006

Nodal signals pattern vertebrate embryos

Tian Tian, Anming Meng

Cellular and Molecular Life Sciences

DOI

2006

Two GC-rich boxes in huC promoter play distinct roles in controlling its neuronal specific expression in zebrafish embryos

Chengtian Zhao, Xinjun He, Chenxi Tian, Anming Meng

Biochemical and Biophysical Research Communications

DOI

2006

Sp5l is a mediator of Fgf signals in anteroposterior patterning of the neuroectoderm in zebrafish embryo

Zhihui Sun, Jue Zhao, Yu Zhang, Anming Meng

Developmental Dynamics

DOI

2006

Tob1 Controls Dorsal Development of Zebrafish Embryos by Antagonizing Maternal β-Catenin Transcriptional Activity

Bo Xiong, Yan‐Ning Rui, Min Zhang, Kehui Shi, Shunji Jia, Tian Tian, Kun Yin, Huizhe Huang, Sheng‐Cai Lin, Sheng‐Cai Lin, Xingang Zhao, Ye-Guang Chen, Ye‐Guang Chen, Sheng‐Cai Lin, Sheng‐Cai Lin, Anming Meng

Developmental Cell

DOI

2006

PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling

Xia Lin, Xueyan Duan, Yao-Yun Liang, Ying Su, Katharine H. Wrighton, Jianyin Long, Min Hu, Candi M. Davis, Jinrong Wang, Francis Charles Brunicardi, Yigong Shi, Ye‐Guang Chen, Anming Meng, Xin‐Hua Feng

Cell

DOI

2005

Functional analysis of mutations in the kinase domain of the TGF-β receptor ALK1 reveals different mechanisms for induction of hereditary hemorrhagic telangiectasia

Yi Gu, Peng Jin, Long Zhang, Xingang Zhao, Xia Gao, Yuanheng Ning, Anming Meng, Ye‐Guang Chen

Blood

DOI

2005

Proliferating cell nuclear antigen (PCNA) as a proliferative marker during embryonic and adult zebrafish hematopoiesis

Anskar YH Leung, Joseph C.K. Leung, Loretta Y.Y. Chan, Edmond S.K. Ma, Tommy T.F. Kwan, K.N. Lai, Anming Meng, Raymond H. S. Liang

Histochemistry and Cell Biology

DOI

2005

Characterization and expression pattern of two zebrafish atf7 genes

Chengtian Zhao, Jingjing Qi, Anming Meng

Developmental Dynamics

DOI

2005

Sp1‐like transcription factors are regulators of embryonic development in vertebrates

Chengtian Zhao, Anming Meng

Development Growth & Differentiation

DOI

2004

斑马鱼shh启动子指导绿色荧光蛋白基因在脊索中的表达

滕鹏，曹莹，王为先，朱少侠，孟安明，张靖溥

Journal of Genetics and Genomics

2004

Generation of mutants with developmental defects in zebrafish by ENU mutagenesis

Peng Jin, Tian Tian, Zhihui Sun, Anming Meng

Chinese Science Bulletin

DOI

2004

Pur alpha and Sp8 as opposing regulators of neural gata2 expression

William Todd Penberthy, Chengtian Zhao, Yu Zhang, Jason R. Jessen, Zhongan Yang, Olivier Bricaud, Andrés Collazo, Anming Meng, Shuo Liang Lin

Developmental Biology

DOI

2004

Zebrafish Dpr2 Inhibits Mesoderm Induction by Promoting Degradation of Nodal Receptors

Lixia Zhang, Lixia Zhang, Hu Zhou, Ying Su, Zhihui Sun, Haiwen Zhang, Long Zhang, Long Zhang, Yu Zhang, Yuanheng Ning, Ye‐Guang Chen, Anming Meng

Science

DOI

2004

fgf17b, a novel member of Fgf family, helps patterning zebrafish embryos

Ying Cao, Jue Zhao, Zhihui Sun, Zhixing Zhao, John H. Postlethwait, Anming Meng

Developmental Biology

DOI

2004

Cloning and expression analysis of zebrafish tob1 gene

Kehui Shi, Lixia Zhang, Anming Meng

Development Genes and Evolution

DOI

2004

Negative regulation of TGF-β signaling in development

Ye-Guang Chen, Anming Meng

Cell Research

DOI

2003

An SP1‐like transcription factor Spr2 acts downstream of Fgf signaling to mediate mesoderm induction

Jue Zhao, Ying Cao, Chengtian Zhao, John H. Postlethwait, Anming Meng

The EMBO Journal

DOI

2003

Two variants of zebrafish p100 are expressed during embryogenesis and regulated by Nodal signaling

Chengtian Zhao, Kehui Shi, Ying Su, Liyun Liang, Yi‐Lin Yan, John H. Postlethwait, Anming Meng

FEBS Letters

DOI

2003

Expression of zebrafish Lc3 synthase gene in embryonic lens requires hedgehog signaling

Ying Cao, Jue Zhao, Ying Wang, Anming Meng

Developmental Dynamics

DOI

2002

Somite-specific expression of a novel fibronectin variant FN3 is negatively regulated by SHH

Chengtian Zhao, Yu Zhang, Ying Su, Anming Meng

《中国科学通报：英文版》

DOI

2002

A novel zinc finger transcription factor resembles krox-20 in structure and in expression pattern in zebrafish

Zhihui Sun, Kehui Shi, Ying Su, Anming Meng

Mechanisms of Development

DOI

2002

Zebrafish sox9b is an early neural crest marker

Ming Li, Chengtian Zhao, Ying Wang, Zhixing Zhao, Anming Meng

Development Genes and Evolution

DOI

2002

The expression of gbx-2 during zebrafish embryogenesis

Ying Su, Anming Meng

Mechanisms of Development

DOI

2002

Induction of cranial and posterior trunk neural crest by exogenous retinoic acid in zebrafish

Ming Li, Ying Su, Anming Meng

DOI

2001

Genomic Organization and Expression in E. coli of Zebrafish Terra

赵知行，华正春，孟安明

Tsinghua Science and Technology

2001

Characterization and expression pattern ofpouII1, a novel class II POU gene in zebrafish

Ming Li, Ying Cao, Zhixing Zhao, Shuo Liang Lin, Anming Meng

Chinese Science Bulletin

DOI

2001

The nuclear localization signal of zebrafish terra is located within the DM domain

Lixiang Zhang, Zhengchun Hua, Jianguo Ren, Anming Meng

FEBS Letters

DOI

2001

The zygotic expression of zebrafish trebf during embryogenesis is restricted to the embryonic shield and its derivatives

Liyun Liang, Ming Li, Ying Wang, Chengtian Zhao, Zhixing Zhao, Anming Meng

Development Genes and Evolution

DOI

2000

Tissue-specific expression of GFP reporter gene in germline driven by GATA-2 promoter and enhancers in zebrafish

Anming Meng, Shuo Liang Lin

Chinese Science Bulletin

DOI

1998

Chapter 7 Transgenesis

Anming Meng, Jason R. Jessen, Shuo Lin

DOI

精选作品

期刊论文

Sclerotomal hematopoiesis in vertebrate embryos contributes to robustness of the blood system

Maternal Huluwa regulates postfertilization microtubule array organization for asymmetrical transport of dorsal determinants in zebrafish

PGC-derived migrasomes couple PGC proliferation with migration

BMP–Smad1/9 signaling plays a critical role in regulating zebrafish PGC proliferation

Stage- and tissue-specific gene editing using 4-OHT–inducible Cas9 in whole organism

Maternal control of embryonic dorsal organizer in vertebrates

Znf706 regulates germ plasm assembly and primordial germ cell development in zebrafish

Aagab is required for zebrafish larval development by regulating neural activity

A Huluwa phosphorylation switch regulates embryonic axis induction

Mapping the chromatin accessibility landscape of zebrafish embryogenesis at single-cell resolution by SPATAC-seq

GPI transamidase complex is required for primordial germ cell migration and development in zebrafish

ULI-ssDRIP-seq revealed R-loop dynamics during vertebrate early embryogenesis

Temporospatial inhibition of Erk signaling is required for lymphatic valve formation

The second polar body contributes to the fate asymmetry in the mouse embryo

Comprehensive maturity of nuclear pore complexes regulates zygotic genome activation

Regulatory factor identification for nodal genes in zebrafish by causal inference

Maternal Factors and Nodal Autoregulation Orchestrate Nodal Gene Expression for Embryonic Mesendoderm Induction in the Zebrafish

The rise of developmental biology in China

TGFβ family signaling and development

5′ Half of specific tRNAs feeds back to promote corresponding tRNA gene transcription in vertebrate embryos

Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs

Migrasomes provide regional cues for organ morphogenesis during zebrafish gastrulation

Sec14l3 potentiates VEGFR2 signaling to regulate zebrafish vasculogenesis

RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay

prpf4 is essential for cell survival and posterior lateral line primordium migration in zebrafish

Maternal Huluwa dictates the embryonic body axis through β-catenin in vertebrates

Maternal Ybx1 safeguards zebrafish oocyte maturation and maternal-to-zygotic transition by repressing global translation

Widespread Enhancer Dememorization and Promoter Priming during Parental-to-Zygotic Transition

The genetic program of oocytes can be modifiedin vivoin the zebrafish ovary

Migrosome and migrocytosis

Nodal/Smad2靶基因的系统鉴定及其在早期胚胎发育中的功能机制

The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis

Hulu, a novel transmembrane protein, is absolutely required for organizer and body axis formation in zebrafish

Comparative profiling of maternal transcriptomes in nonsense and frameshift eomesa mutants in zebrafish

The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling

Author response: The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling

Alkbh4 and Atrn Act Maternally to Regulate Zebrafish Epiboly

The rising zebrafish research in China: Meeting report of the 3rd Chinese Zebrafish Principal Investigator Meeting & the Inaugural Meeting of China Zebrafish Society

Allelic reprogramming of the histone modification H3K4me3 in early mammalian development

Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation

Eph-ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizer

Impairment of Cargo Transportation Caused by gbf1 Mutation Disrupts Vascular Integrity and Causes Hemorrhage in Zebrafish Embryos

Embryonic hematopoiesis in vertebrate somites gives rise to definitive hematopoietic stem cells

PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling.

Coordinate involvement of Nodal-dependent inhibition and Wnt-dependent activation in the maintenance of organizer-specific bmp2b in zebrafish.

The Kinase Activity-deficient Isoform of the Protein Araf Antagonizes Ras/Mitogen-activated Protein Kinase (Ras/MAPK) Signaling in the Zebrafish Embryo

The Chromatin Remodeling Protein Bptf Promotes Posterior Neuroectodermal Fate by Enhancing Smad2-Activated wnt8a Expression

TGFβ1a regulates zebrafish posterior lateral line formation via Smad5 mediated pathway

斑马鱼母源因子在胚胎发育中的作用

Inhibition of endothelial ERK signalling by Smad1/5 is essential for haematopoietic stem cell emergence

Organizer-derived Bmp2 is required for the formation of a correct Bmp activity gradient during embryonic development

Destabilizing LSD1 by Jade-2 Promotes Neurogenesis: An Antibraking System in Neural Development

Maternal Eomesodermin regulates zygotic nodal gene expression for mesendoderm induction in zebrafish embryos

Faculty Opinions recommendation of Construction of a vertebrate embryo from two opposing morphogen gradients.

Uracil-DNA Glycosylase Is Involved in DNA Demethylation and Required for Embryonic Development in the Zebrafish Embryo

Maternal Factors Regulate Embryonic Development in Zebrafish

MicroRNA-92a Upholds Bmp Signaling by Targeting noggin3 during Pharyngeal Cartilage Formation

Araf kinase antagonizes Nodal-Smad2 activity in mesendoderm development by directly phosphorylating the Smad2 linker region

Faculty Opinions recommendation of A molecular base for cell sorting at embryonic boundaries: contact inhibition of cadherin adhesion by ephrin/ Eph-dependent contractility.

中国斑马鱼研究发展历程及现状

Protein Phosphatase 4 Cooperates with Smads to Promote BMP Signaling in Dorsoventral Patterning of Zebrafish Embryos

β-Catenin 1 and β-catenin 2 play similar and distinct roles in left-right asymmetric development of zebrafish embryos

Midbrain-hindbrain boundary patterning and morphogenesis are regulated by diverse grainy head-like 2-dependent pathways

Loss of Zygotic NUP107 Protein Causes Missing of Pharyngeal Skeleton and Other Tissue Defects with Impaired Nuclear Pore Function in Zebrafish Embryos

The Tiny Zebrafish Keep Swimming Fast in the Developmental Biology Pond

MicroRNA-206 Regulates Cell Movements during Zebrafish Gastrulation by Targeting prickle1a and Regulating c-Jun N-Terminal Kinase 2 Phosphorylation

The Amotl2 Gene Inhibits Wnt/β-Catenin Signaling and Regulates Embryonic Development in Zebrafish

Genomic organization and expression in E. coli of Zebrafish terra

Angiomotin-like2 Gene (amotl2) Is Required for Migration and Proliferation of Endothelial Cells during Angiogenesis

Global Identification of SMAD2 Target Genes Reveals a Role for Multiple Co-regulatory Factors in Zebrafish Early Gastrulas

SCFFBXL15 regulates BMP signalling by directing the degradation of HECT‐type ubiquitin ligase Smurf1

Transmembrane Protein 198 Promotes LRP6 Phosphorylation and Wnt Signaling Activation

Interruption of cenph Causes Mitotic Failure and Embryonic Death, and Its Haploinsufficiency Suppresses Cancer in Zebrafish

S21-02. Regulation of TGF-beta signalling by Dapper2 in vertebrate development

Smad2/3 activities are required for induction and patterning of the neuroectoderm in zebrafish

Rock2 controls TGFβ signaling and inhibits mesoderm induction in zebrafish embryos

Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos

A zebrafish gene trap line expresses GFP recapturing expression pattern of foxj1b