百晓学者学者目录

王娟

博士生导师、教授，北京工业大学

精选作品

期刊论文

2026

HRD1 negatively regulates autolysosome formation by inhibiting liquid-liquid phase separation of SNAP29

Wenyan Qu, Di Chen, Hongyu Zhao, Qiang Sheng, Juan Wang, Yujun Shen, Yuxian Shen, Yuxian Shen, Yuxian Shen

Cell Reports

DOI

2026

A Dedicated ATG9A Vesicle Pathway for Selective Unconventional Protein Secretion

Yuean Wang, Haolin Zhang, Huijie Han, Juan Wang

Ubiquitylation & Atg8ylation

DOI

2025

Author Correction: Recruitment of Atg1 to the phagophore by Atg8 orchestrates autophagy machineries

Jing-Zhen Song, Hui Li, Haiyan Yang, Rui Liu, Wenting Zhang, Tianlong He, Meng-Xi Xie, Chen Chen, Li Cui, Shian Wu, Yueguang Rong, Lifeng Pan, Jing Zhu, Qingqiu Gong, Juan Wang, Zhao Qin, Zhiping Xie

Nature Structural & Molecular Biology

DOI

2025

Beyond the Secretory Pathway: New Insights Into Protein Release

Ruey‐Hwa Chen, Antonio Jose Costa-Filho, Jayanta Debnath, Thierry Galli, Liang Ge, Deborah C. I. Goberdhan, Wei Peng Guo, Kangmin He, Ralf Jacob, Tiebang Kang, Min Goo Lee, Lian Li, Fabio Lolicato, Jun Lü, Vivek Malhotra, Walter Nickel, Vassiliki Nikoletopoulou, Stacey K. Ogden, Georgia Maria Sagia, Feng Shao, Anbing Shi, Clotilde Théry, Christel Vérollet, Julien Villeneuve, Frederik J. Verweij, Yanzhuang Wang, Juan Wang, Shenjie Wu, Yihong Ye, Hang Yin, Li Yu, Min Zhang, Ying Zhang, Xin Zhou, Chiara Zurzolo

Traffic

DOI

2025

Pbs2 regulates late‐stage macroautophagy in Saccharomyces cerevisiae

Jianing Song, Haolin Zhang, Xingyu Cao, Zizhang Ren, Chao Tian, Miao Jia, Meiling Wu, Xiaoli Wang, Juan Wang

Animal Models and Experimental Medicine

DOI

2025

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion

Wenting Zhang, Cuicui Ji, Xianghua Li, Tianlong He, Wei Jiang, Yukun Liu, Meiling Wu, Yunpeng Zhao, Xuechai Chen, Xiaoli Wang, Jian Li, Haolin Zhang, Juan Wang

Nature Communications

DOI

2025

Recruitment of Atg1 to the phagophore by Atg8 orchestrates autophagy machineries

Jing-Zhen Song, Hui Li, Haiyan Yang, Rui Liu, Wenting Zhang, Tianlong He, Meng-Xi Xie, Chen Chen, Li Cui, Shian Wu, Yueguang Rong, Lifeng Pan, Jing Zhu, Qingqiu Gong, Juan Wang, Zhao Qin, Zhiping Xie

Nature Structural & Molecular Biology

DOI

2025

RHOD mediates ATG9A trafficking to promote autophagosome formation during autophagy in cancer

Sijia Wang, Jing Ren, Jinghan Chi, Yifei Guan, Ran Zheng, Juan Wang, Xinhui Liu, Hua Huang

Autophagy

DOI

2025

The diverse functions of syntaxin 13 in endosome-mediated membrane fusion

Wenting Zhang, Haolin Zhang, Tianlong He, Xianghua Li, Yukun Liu, Huijie Han, Juan Wang

International Journal of Biological Macromolecules

DOI

2025

Molecular mechanisms and pathological implications of unconventional protein secretion in human disease: from cellular stress to therapeutic targeting

Yukun Liu, Haolin Zhang, Xianghua Li, Tianlong He, Wenting Zhang, Cuicui Ji, Juan Wang

Molecular Biology Reports

DOI

2024

The COPII coat protein SEC 24 D is required for autophagosome closure in mammals

Tianlong He, Cuicui Ji, Wenting Zhang, Xianghua Li, Yukun Liu, Xiaoli Wang, Haolin Zhang, Juan Wang

FEBS Letters

DOI

2024

Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy

Jianan Wang, Yuanyuan Ran, Zihan Li, Tianyuan Zhao, Fangfang Zhang, Juan Wang, Zongjian Liu, Xuechai Chen

Neural Regeneration Research

DOI

2023

Spatial chromatin accessibility sequencing resolves high-order spatial interactions of epigenomic markers

Yeming Xie, Fengying Ruan, Ya-Ning Li, Meng Luo, Chen Zhang, Zhi-Chao Chen, Zhe Xie, Z. Weng, Wei-Tian Chen, Wen-Fang Chen, Yitong Fang, Yuxin Sun, M. Guo, Juan Wang, Shou-Ping Xu, Hongqi Wang, Chong Tang

bioRxiv

DOI

2023

BIND&MODIFY: a long-range method for single-molecule mapping of chromatin modifications in eukaryotes

Z. Weng, Fengying Ruan, Wei-Tian Chen, Zhi-Chao Chen, Yeming Xie, Meng Luo, Zhe Xie, Chen Zhang, Juan Wang, Yuxin Sun, Yitong Fang, M. Guo, Chen Tan, Wen-Fang Chen, Yi-Qin Tong, Ya-Ning Li, Hongqi Wang, Chong Tang

Genome Biology

DOI

2023

Improving the RNA velocity approach with single-cell RNA lifecycle (nascent, mature and degrading RNAs) sequencing technologies

Chen Zhang, Yitong Fang, Wei-Tian Chen, Zhi-Chao Chen, Ying Zhang, Yeming Xie, Wen-Fang Chen, Zhe Xie, M. Guo, Juan Wang, Chen Tan, Hongqi Wang, Chong Tang

Nucleic Acids Research

DOI

2023

TOR‐mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly

Weijing Yao, Yuting Chen, Yingcong Chen, Pengwei Zhao, Jing Liu, Yi Zhang, Qiang Jiang, Choufei Wu, Yu Xie, Siyu Fan, Miao Ye, Yigang Wang, Yuyao Feng, Xue Bai, Mingzhu Fan, Shan Feng, Juan Wang, Yixian Cui, Hongguang Xia, Cheng Ma, Zhiping Xie, Liqin Zhang, Qiming Sun, Wei Liu, Cong Yi

The EMBO Journal

DOI

2023

Cellular response to β‐amyloid neurotoxicity in Alzheimer's disease and implications in new therapeutics

Haolin Zhang, Xianghua Li, Xiaoli Wang, Jiayu Xu, Felice Elefant, Juan Wang

Animal Models and Experimental Medicine

DOI

2022

Spatial chromatin accessibility sequencing resolves next-generation genome architecture

Yeming Xie, Ya-Ning Li, Fengying Ruan, Chen Zhang, Zhi-Chao Chen, Zhe Xie, Z. Weng, Wei-Tian Chen, Wen-Fang Chen, Yitong Fang, Yuxin Sun, M. Guo, Juan Wang, Hongqi Wang, Chong Tang

2022

High coverage of single cell genomes by T7-assisted enzymatic methyl-sequencing

Juan Wang, Yitong Fang, Wen-Fang Chen, Chen Zhang, Zhi-Chao Chen, Zhe Xie, Z. Weng, Wei-Tian Chen, Fengying Ruan, Yeming Xie, Yuxin Sun, M. Guo, Ya-Ning Li, Chong Tang

bioRxiv

DOI

2022

Improving the RNA velocity approach using long-read single cell sequencing

Chen Zhang, Wei-Tian Chen, Yitong Fang, Zhi-Chao Chen, Yeming Xie, Wen-Fang Chen, Zhe Xie, M. Guo, Juan Wang, Chen Tan, Hongqi Wang, Chong Tang

bioRxiv

DOI

2022

TFIIB-related factor 1 is a nucleolar protein that promotes RNA polymerase I-directed transcription and tumour cell growth

Juan Wang, Qiyue Chen, Xin Wang, Sha-Sha Zhao, Huan Deng, B. Guo, Cheng Zhang, Xiaoye Song, W. Deng, Shihua Zhang, Tong-Cun Zhang, Hong-Wei Ni

bioRxiv

DOI

2022

LncRNA Pnky Positively Regulates Neural Stem Cell Migration by Modulating mRNA Splicing and Export of Target Genes

Jian-Sheng Du, Yuan Li, Yuting Su, Wen-Qian Zhi, Jia-Le Zhang, Cheng Zhang, Juan Wang, W. Deng, Sha-Sha Zhao

Cellular and molecular neurobiology

DOI

2022

STAT3 promotes RNA polymerase III-directed transcription by controlling the miR-106a-5p/TP73 axis

Cheng Zhang, Sha-Sha Zhao, Huan Deng, Shi-Hua Zhang, Juan Wang, Xiaoye Song, De'en Yu, Yue Zhang, W. Deng

bioRxiv

DOI

2022

L3MBTL2-mediated CGA transcriptional suppression promotes pancreatic cancer progression through modulating autophagy

Hua Huang, Ruining Pan, Yue Zhao, Huan Li, Huiyu Zhu, Sijia Wang, Aamir Ali Khan, Juan Wang, Xinhui Liu

iScience

DOI

2022

Sal synthase induced cytotoxicity of PC12 cells through production of the dopamine metabolites salsolinol and N-methyl-salsolinol

Qianqian Xiong, Xiaotong Zheng, Jianan Wang, Zixuan Chen, Yulin Deng, Rugang Zhong, Juan Wang, Xuechai Chen

Journal of Integrative Neuroscience

DOI

2021

Sequencing of methylase-accessible regions in integral circular extrachromosomal DNA reveals differences in chromatin structure

Weitian Chen, Z. Weng, Zhe Xie, Yeming Xie, Chen Zhang, Zhi-Chao Chen, Fengying Ruan, Juan Wang, Yuxin Sun, Yitong Fang, M. Guo, Yi-Qin Tong, Ya-Ning Li, Chong Tang

Epigenetics & Chromatin

DOI

2021

BIND&MODIFY: Long-range single-molecule mapping of chromatin modification in eukaryotes v1

Z. Weng, Fengying Ruan, Weitian Chen, Zhe Xie, Yeming Xie, Chen Zhang, Zhi-Chao Chen, Juan Wang, Yuxin Sun, Yitong Fang, M. Guo, Yi-Qin Tong, Ya-Ning Li, Chong Tang

DOI

2021

CDCA-seq resolve the different chromatin structure on integral circular DNAs

Weitian Chen, Z. Weng, Zhe Xie, Yeming Xie, Chen Zhang, Zhi-Chao Chen, Fengying Ruan, Juan Wang, Yuxin Sun, Yitong Fang, M. Guo, Yi-Qin Tong, Ya-Ning Li, Chong Tang

2021

A high-efficiency method for site-directed mutagenesis of large plasmids based on large DNA fragment amplification and recombinational ligation

Kewei Zhang, X. Yin, Kaituo Shi, Shi-Hua Zhang, Juan Wang, Sha-Sha Zhao, Huan Deng, Cheng Zhang, Zi-Hui Wu, Yuan Li, Xiangyu Zhou, W. Deng

Scientific Reports

DOI

2021

RNA polymerase I subunit 12 plays opposite roles in cell proliferation and migration.

X. Yin, Kewei Zhang, Juan Wang, Xiangyu Zhou, Cheng Zhang, Xiaoye Song, Zhong-Wei Wu, Jiannan Du, Qiyue Chen, Shi-Hua Zhang, W. Deng

Biochemical and Biophysical Research Communications - BBRC

DOI

2021

Emerging role of RNA modification N6-methyladenosine in immune evasion

Xin Lou, Juan Wang, Yaqing Wei, Jin-Jin Sun

Cell Death and Disease

DOI

2021

Current insights into the implications of m6A RNA methylation and autophagy interaction in human diseases

Xuechai Chen, Jianan Wang, Jianan Wang, Muhammad Tahir, Fangfang Zhang, Yuanyuan Ran, Zongjian Liu, Juan Wang, Juan Wang

Cell & Bioscience

DOI

2021

Key Regulators of Autophagosome Closure

Wenyan Jiang, Xuechai Chen, Cuicui Ji, Wenting Zhang, Jianing Song, Jie Li, Juan Wang

Cells

DOI

2020

m6A-dependent biogenesis of circular RNAs in male germ cells

Chong Tang, Yeming Xie, Tian Yu, Na Liu, Zhuqing Wang, Rebekah J. Woolsey, Yun-Ge Tang, Xin-Zong Zhang, Wei-Bing Qin, Ying Zhang, Ge Song, Wei-Wei Zheng, Juan Wang, Weitian Chen, Xiongyi Wei, Zhe Xie, Rachel Klukovich, Huili Zheng, D. Quilici, Wei Yan

Cell Research

DOI

2020

Disruption of the interaction between TFIIAαβ and TFIIA recognition element inhibits RNA polymerase II gene transcription in a promoter context-dependent manner.

Juan Wang, Kaituo Shi, Zi-Hui Wu, Cheng Zhang, Yuan Li, Huan Deng, Sha-Sha Zhao, W. Deng

Biochimica et Biophysica Acta. Gene Regulatory Mechanisms

DOI

2020

The transcription factor Sp1 modulates RNA polymerase III gene transcription by controlling BRF1 and GTF3C2 expression in human cells

Feixia Peng, Ying Zhou, Juan Wang, B. Guo, Yun Wei, Huan Deng, Zi-Hui Wu, Cheng Zhang, Kaituo Shi, Yuan Li, Xin Wang, Paul Shore, Sha-Sha Zhao, W. Deng

Journal of Biological Chemistry

DOI

2020

Casein Kinase 1 Family Member CK1δ/Hrr25 Is Required for Autophagosome Completion

Yuting Li, Xuechai Chen, Qianqian Xiong, Yong Chen, Hongyu Zhao, Muhammad Tahir, Jingdong Song, Bing Zhou, Juan Wang

Frontiers in Cell and Developmental Biology

DOI

2019

A novel method to investigate the effects of gene mutations at the cellular level using a dual expression lentiviral vector

Liyun Huang, Feixia Peng, Yun Wei, Wei-Cong He, Sha-Sha Zhao, Juan Wang, Yang Zhang, Hou-Liang Zhao, W. Deng

Bioscience Reports

DOI

2019

A two‐buffer method used for both polymerase chain reaction product purification and DNA gel extraction

Zi-Hui Wu, Hou-Liang Zhao, Cheng Zhang, Juan Wang, Sha-Sha Zhao, Kaituo Shi, W. Deng

Journal of Chemical Technology & Biotechnology

DOI

2019

Down-Regulation of m6A mRNA Methylation Is Involved in Dopaminergic Neuronal Death

Xuechai Chen, Chunyu Yu, Minjun Guo, Xiaotong Zheng, Sakhawat Ali, Hua Huang, Lihua Zhang, Shensen Wang, Yinghui Huang, Shuyan Qie, Juan Wang

ACS Chemical Neuroscience

DOI

2019

内质网在纳米材料毒性效应形成中的作用及机制

王娟，徐文娟，王信文，王晶晶，王妹梅，许安

《生物化学与生物物理进展》

2018

Rapid Regeneration and Reuse of Silica Columns from PCR Purification and Gel Extraction Kits

Ying Zhou, Yang Zhang, Wei-Cong He, Juan Wang, Feixia Peng, Liyun Huang, Sha-Sha Zhao, W. Deng

Scientific Reports

DOI

2017

A transcription factor IIA-binding site differentially regulates RNA polymerase II-mediated transcription in a promoter context-dependent manner

Juan Wang, Sha-Sha Zhao, Wei-Cong He, Yun Wei, Yang Zhang, H. Pegg, Paul Shore, S. Roberts, W. Deng

Journal of Biological Chemistry

DOI

2017

The analysis of viability for mammalian cells treated at different temperatures and its application in cell shipment

Juan Wang, Yun Wei, Sha-Sha Zhao, Ying Zhou, Wei-Cong He, Yang Zhang, W. Deng

PLoS ONE

DOI

2017

Autophagosome formation: Where the secretory and autophagy pathways meet

Juan Wang, Saralin Davis, Ming Zhu, Elizabeth A. Miller, Susan Ferro‐Novick

Autophagy

DOI

2016

Cytoskeletal Filamin A Differentially Modulates RNA Polymerase III Gene Transcription in Transformed Cell Lines*

Juan Wang, Sha-Sha Zhao, Yun Wei, Ying Zhou, Paul Shore, W. Deng

Journal of Biological Chemistry

DOI

2015

Establishment and Validation of a Non-Radioactive Method for In Vitro Transcription Assay Using Primer Extension and Quantitative Real Time PCR

Juan Wang, Sha-Sha Zhao, Ying Zhou, Yun Wei, W. Deng

PLoS ONE

DOI

2015

Validation of the novel method by analysis of core promoter elements.

Juan Wang, Sha-Sha Zhao, Ying Zhou, Yun Wei, W. Deng

DOI

2015

The Ct values from qPCR for E4 and ML in vitro transcription assays by primer extension under the conditions with or without reverse transcriptase.

Juan Wang, Sha-Sha Zhao, Ying Zhou, Yun Wei, W. Deng

DOI

书籍章节

2021

Methods for Assessing the Regulation of a Kinase by the Rab GTPase Ypt1

Juan Wang, Shensen Wang, Susan Ferro‐Novick

Methods in molecular biology

DOI

研究方向

细胞压力应对与人类重大疾病

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