孙雨蒙｜南方医科大学｜学者主页

2026

RBM15B recognizes H3K79me2 to guide selective m6A-modification of mRNA and enhance oncoprotein translation in MLL-r leukemia

Tian-Qi Chen, Yumeng Sun, Shun-Xin Zhu, Xiao-Tong Chen, Ke-Jia Pu, Heng-Jing Huang, Qi Pan, Jun-Yi Lian, Wei Huang, Ke Fang, Xue-Qun Luo, Li-Bin Huang, Yue-Qin Chen, Wen-Tao Wang

EMBO Journal

DOI

2025

Chromatin-associated circRNA ciCRLF3(2) regulates cell differentiation blockage via activating non-homologous end joining–based DNA repair

Ke-Jia Pu, Xiao-Tong Chen, Shun-Xin Zhu, Yan An, Xin-Yi Feng, Heng-Jing Huang, Cheng Zhou, Mei Ye, Yun-Chun Wei, Yi-Xuan Ma, C. Fang, Nan Zhang, Dan Wang, Bin Han, Jun-Yi Lian, Tian-Qi Chen, Yumeng Sun, Yue-Qin Chen, Wen-Tao Wang

Cell Death and Differentiation

DOI

2025

Protocol for investigating phase transition of prion-like proteins in vitro with concentration variation

Xiao-Tong Chen, Yumeng Sun, Wen-Tao Wang, Yue-Qin Chen, Tian-Qi Chen

STAR Protocols

DOI

2024

lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing.

Yumeng Sun, Shun-Xin Zhu, Xiao-Tong Chen, Qi Pan, Yan An, Tian-Qi Chen, Heng-Jing Huang, Ke-Jia Pu, Jun-Yi Lian, Wen-Long Zhao, Wen-Tao Wang, Yue-Qin Chen

Molecules and Cells

DOI

2024

Blockade of the lncRNA-DOT1L-LAMP5 axis enhances autophagy and promotes degradation of MLL fusion proteins

Tian-Qi Chen, Heng-Jing Huang, Shun-Xin Zhu, Xiao-Tong Chen, Ke-Jia Pu, Dan Wang, Yan An, Jun-Yi Lian, Yumeng Sun, Yue-Qin Chen, Wen-Tao Wang

Experimental Hematology & Oncology

DOI

2023

METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m6A homeostasis

Zhancheng Zeng, Qi Pan, Yumeng Sun, Heng-Jing Huang, Xiao-Tong Chen, Tian-Qi Chen, Bo He, Hua Ye, Shun-Xin Zhu, Ke-Jia Pu, Ke Fang, Wei Huang, Yue-Qin Chen, Wen-Tao Wang

EMBO Reports

DOI

2022

The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1

Wei Huang, Yumeng Sun, Qi Pan, Ke Fang, Xiao-Tong Chen, Zhancheng Zeng, Tian-Qi Chen, Shun-Xin Zhu, Li-Bin Huang, Xue-Qun Luo, Wen-Tao Wang, Yue-Qin Chen

Cell Discovery

DOI

2022

Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex.

Cai Han, Lin-Yu Sun, Xue-Qun Luo, Qi Pan, Yumeng Sun, Zhancheng Zeng, Tian-Qi Chen, Wei Huang, Ke Fang, Wen-Tao Wang, Yue-Qin Chen

Cell Reports

DOI

2021

Correction to: The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia

Wen-Tao Wang, Tian-Qi Chen, Zhancheng Zeng, Qi Pan, Wei Huang, Cai Han, Ke Fang, Lin-Yu Sun, Qianqian Yang, Dan Wang, Xue-Qun Luo, Yumeng Sun, Yue-Qin Chen

Journal of Hematology & Oncology

DOI

2021

Demethylation of miR-34a upregulates expression of membrane palmitoylated proteins and promotes the apoptosis of liver cancer cells

Fu-yong Li, Ting-Ting Fan, Hao Zhang, Yumeng Sun

World Journal of Gastroenterology

DOI

2021

A CRISPR/CAS9‐based strategy targets the personalized chimeric neosequence in fusion‐driven cancer genome for precision medicine

Wei Huang, Zhancheng Zeng, Wen-Tao Wang, Yumeng Sun, Yue-Qin Chen, Xue-Qun Luo, Ke Fang

Clinical and Translational Medicine

DOI

2021

The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation.

Lin-Yu Sun, Wen-Tao Wang, Cai Han, Wei Huang, Yumeng Sun, Ke Fang, Zhancheng Zeng, Qianqian Yang, Qi Pan, Tian-Qi Chen, Xue-Qun Luo, Yue-Qin Chen

Molecules and Cells

DOI

2021

Polysome profiling followed by quantitative PCR for identifying potential micropeptide encoding long non-coding RNAs in suspension cell lines

Cai Han, Lin-Yu Sun, Qi Pan, Yumeng Sun, Wen-Tao Wang, Yue-Qin Chen

STAR Protocols

DOI

2021

Small nucleolar RNA is potential as a novel player in leukemogenesis and clinical application

Li-Min Lin, Qi Pan, Yumeng Sun, Wen-Tao Wang

Blood Science

DOI

2020

The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia

Wen-Tao Wang, Tian-Qi Chen, Zhancheng Zeng, Qi Pan, Wei Huang, Cai Han, Ke Fang, Lin-Yu Sun, Qianqian Yang, Dan Wang, Xue-Qun Luo, Yumeng Sun, Yue-Qin Chen

Journal of Hematology & Oncology

DOI

2020

Exosome-mediated miR-1290 regulation of SLU7 affects hepatocellular carcinoma process

Fu-yong Li, Ting-Ting Fan, Hao Zhang, Yumeng Sun

DOI

2020

Principles and innovative technologies for decrypting noncoding RNAs: from discovery and functional prediction to clinical application

Yumeng Sun, Yue-Qin Chen

Journal of Hematology & Oncology

DOI

2020

Cis-acting lnc-eRNA SEELA directly binds histone H4 to promote histone recognition and leukemia progression

Ke Fang, Wei Huang, Yumeng Sun, Tian-Qi Chen, Zhancheng Zeng, Qianqian Yang, Qi Pan, Cai Han, Lin-Yu Sun, Xue-Qun Luo, Wen-Tao Wang, Yue-Qin Chen

Genome Biology

DOI

2019

circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression

Wei Huang, Ke Fang, Tian-Qi Chen, Zhancheng Zeng, Yumeng Sun, Cai Han, Lin-Yu Sun, Zhen-Hua Chen, Qianqian Yang, Qi Pan, Xue-Qun Luo, Wen-Tao Wang, Yue-Qin Chen

Journal of Hematology & Oncology

DOI

2019

Activation of the Lysosome-Associated Membrane Protein LAMP5 by DOT1L Serves as a Bodyguard for MLL Fusion Oncoproteins to Evade Degradation in Leukemia

Wen-Tao Wang, Cai Han, Yumeng Sun, Zhen-Hua Chen, Ke Fang, Wei Huang, Lin-Yu Sun, Zhancheng Zeng, Xue-Qun Luo, Yue-Qin Chen

Clinical Cancer Research

DOI

2019

CircMYBL2, a circRNA from MYBL2, Regulates FLT3 Translation by Recruiting PTBP1 to Promote FLT3-ITD AML Progression.

Yumeng Sun, Wen-Tao Wang, Zhancheng Zeng, Tian-Qi Chen, Cai Han, Qi Pan, Wei Huang, Ke Fang, Lin-Yu Sun, Yan-Fei Zhou, Xue-Qun Luo, C. Luo, Xin Du, Yue-Qin Chen

Blood

DOI

2019

Non-coding RNAs in cancers with chromosomal rearrangements: the signatures, causes, functions and implications

Cai Han, Lin-Yu Sun, Wen-Tao Wang, Yumeng Sun, Yue-Qin Chen

Journal of Molecular Cell Biology

DOI

2019

Noncoding RNAs in cancer therapy resistance and targeted drug development

Wen-Tao Wang, Cai Han, Yumeng Sun, Tian-Qi Chen, Yue-Qin Chen

Journal of Hematology & Oncology

DOI

2018

Nuclear export of chimeric mRNAs depends on an lncRNA-triggered autoregulatory loop in blood malignancies

Zhen-Hua Chen, Tian-Qi Chen, Zhancheng Zeng, Dan Wang, Cai Han, Yumeng Sun, Wei Huang, Lin-Yu Sun, Ke Fang, Yue-Qin Chen, Xue-Qun Luo, Wen-Tao Wang

Cell Death and Disease

DOI

2018

MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47

Wei Huang, Wen-Tao Wang, Ke Fang, Zhen-Hua Chen, Yumeng Sun, Cai Han, Lin-Yu Sun, Xue-Qun Luo, Yue-Qin Chen

Molecular Cancer

DOI

2018

LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1

Lin-Yu Sun, Xiao-juan Li, Yumeng Sun, Wei Huang, Ke Fang, Cai Han, Zhen-Hua Chen, Xue-Qun Luo, Yue-Qin Chen, Wen-Tao Wang

Molecular Cancer

DOI

2016

Genome-wide Long Non-coding RNA Analysis Identified Circulating LncRNAs as Novel Non-invasive Diagnostic Biomarkers for Gynecological Disease

Wen-Tao Wang, Yumeng Sun, Wei Huang, Bo He, Ya-Nan Zhao, Yue-Qin Chen

Scientific Reports

DOI

2016

The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway

Zhen-Hua Chen, Wen-Tao Wang, Wei Huang, Ke-ying Fang, Yumeng Sun, Shu-Rong Liu, Xue-Qun Luo, Yue-Qin Chen

Cell Death and Differentiation

DOI

2015

MiR-34c suppresses tumor growth and metastasis in nasopharyngeal carcinoma by targeting MET

Yuan-Hua Li, Xian-Yue Ren, Qiu-Rong He, Yi Xu, Xinran Tang, Yumeng Sun, Mu-Sheng Zeng, Tie-Bang Kang, Na Liu, Jun Ma

Cell Death and Disease

DOI

2013

Diverse functions of miR-125 family in different cell contexts

Yumeng Sun, Kang-Yu Lin, Yue-Qin Chen

Journal of Hematology & Oncology

DOI

孙雨蒙

精选作品

期刊论文

RBM15B recognizes H3K79me2 to guide selective m6A-modification of mRNA and enhance oncoprotein translation in MLL-r leukemia

Chromatin-associated circRNA ciCRLF3(2) regulates cell differentiation blockage via activating non-homologous end joining–based DNA repair

Protocol for investigating phase transition of prion-like proteins in vitro with concentration variation

lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing.

Blockade of the lncRNA-DOT1L-LAMP5 axis enhances autophagy and promotes degradation of MLL fusion proteins

METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m6A homeostasis

The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1

Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex.

Correction to: The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia

Demethylation of miR-34a upregulates expression of membrane palmitoylated proteins and promotes the apoptosis of liver cancer cells

A CRISPR/CAS9‐based strategy targets the personalized chimeric neosequence in fusion‐driven cancer genome for precision medicine

The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation.

Polysome profiling followed by quantitative PCR for identifying potential micropeptide encoding long non-coding RNAs in suspension cell lines

Small nucleolar RNA is potential as a novel player in leukemogenesis and clinical application

The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia

Exosome-mediated miR-1290 regulation of SLU7 affects hepatocellular carcinoma process

Principles and innovative technologies for decrypting noncoding RNAs: from discovery and functional prediction to clinical application

Cis-acting lnc-eRNA SEELA directly binds histone H4 to promote histone recognition and leukemia progression

circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression

Activation of the Lysosome-Associated Membrane Protein LAMP5 by DOT1L Serves as a Bodyguard for MLL Fusion Oncoproteins to Evade Degradation in Leukemia

CircMYBL2, a circRNA from MYBL2, Regulates FLT3 Translation by Recruiting PTBP1 to Promote FLT3-ITD AML Progression.

Non-coding RNAs in cancers with chromosomal rearrangements: the signatures, causes, functions and implications

Noncoding RNAs in cancer therapy resistance and targeted drug development

Nuclear export of chimeric mRNAs depends on an lncRNA-triggered autoregulatory loop in blood malignancies

MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47

LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1

Genome-wide Long Non-coding RNA Analysis Identified Circulating LncRNAs as Novel Non-invasive Diagnostic Biomarkers for Gynecological Disease

The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway

MiR-34c suppresses tumor growth and metastasis in nasopharyngeal carcinoma by targeting MET

Diverse functions of miR-125 family in different cell contexts

会议论文

LncRNA HOTAIRM1在急性早幼粒性细胞白血病中的功能及分子机制

研究方向