林叶｜东北农业大学｜学者主页

2026

Methionine promotes cell proliferation in bovine mammary epithelial cells via the ATF4-GSK3β signalling pathway

Yanying Zhang, Yalin Xie, Meiyan Liu, Fengxian Sui, Jing Gao, Jiadi Su, Yang Yang, Ye Lin, Xiaoming Hou, Na Zhang

Journal of Dairy Research

DOI

2026

NRF2-CD36 Axis-Mediated Oleic Acid-Induced Milk Fat Production in Dairy Cow Mammary Epithelial Cells

Caiyan Zhang, Fengxian Sui, Meiyan Liu, Yalin Xie, Jiadi Su, Jing Gao, Ye Lin, Yang Yang, Xiaoming Hou

Journal of Agricultural and Food Chemistry

DOI

2026

Oxidative stress inhibits milk fat production by p38 MAPK-Cebpα-Acsl6 axis in mouse mammary gland.

Xiaoxue Wang, Jiadi Su, Jing Gao, Mei-Yan Liu, Feng-Xiang Sui, Yalin Xie, Zhihui Wang, Ye Lin, Yang Yang, Xiaomin Hou

Free Radical Biology & Medicine

DOI

2025

CD146基因参与乙酸钠对奶牛乳腺上皮细胞乳脂合成的调节

徐自如，葛慧聚，刘佳琪，随风贤，刘美妍，杨洋，侯晓明，林叶

《东北农业大学学报》

2024

GPR37L1对奶牛乳腺上皮细胞乳成分合成相关基因表达的影响

邢鹏飞，王晓雪，王智慧，谢雅琳，杨洋，侯晓明，林叶

《东北农业大学学报》

2024

MMP23B对奶牛乳腺上皮细胞乳脂合成影响的研究

王波，谢佳秀，孙宇，邢鹏飞，杨洋，侯晓明，林叶

《东北农业大学学报》

DOI

2024

Prolactin upregulates amino acid uptake in dairy cow mammary epithelial cells via LAT1

Xiaoming Hou, Shuyuan Song, Ziru Xu, Ying Shi, Yang Yang, Li Zhang, Yingjun Cui, Chunmei Wang, Ye Lin

Journal of Dairy Science

DOI

2024

Transcriptomic analysis reveals that prolactin modulates the β-casein synthesis mechanism in bovine mammary epithelial cells

Yanying Zhang, Ziru Xu, Xiaoxue Wang, Xiaoming Hou, Yang Yang, Ying Liu, Ye Lin

Journal of Dairy Research

DOI

2024

Leptin signaling promotes milk fat synthesis via PI3K/AKT/mTOR/SREBP1 in mammary gland of dairy cow

Yang Yang, Zhihui Wang, Huiju Ge, Bo Wang, Pengfei Xing, Nan Wang, Zhi-Yi Song, Ye Lin, Xiao-Ming Hou

Journal of Dairy Research

DOI

2023

mTORC2‐AKT‐LAT1 signalling participates in methionine‐induced β‐CASEIN expression in mammary epithelial cells of dairy cows

Xiaoyu Duan, Chuanping Liu, Xiaoqing Gong, Yang Yang, Hongtao Jiao, Ye Lin, Xiaoming Hou

Journal of Animal Physiology and Animal Nutrition

DOI

2023

Acetate Upregulates GPR43 Expression and Function via PI3K-AKT-SP1 Signaling in Mammary Epithelial Cells during Milk Fat Synthesis

Yang Yang, Chuanping Liu, Caiyan Zhang, Ziru Xu, Li Zhang, Yingjun Cui, Chunmei Wang, Ye Lin, Xiaoming Hou

Journal of Agricultural and Food Chemistry

DOI

2022

AGPAT6在奶牛乳腺上皮细胞乳脂合成中的功能研究

林叶，刘灿，江怡，宫晓庆，刘川萍，杨洋，侯晓明

《东北农业大学学报》

2022

奶牛SP1基因结构及对乳脂合成功能的初步分析

杨洋，周子薇，张京一，杨硕，王博宇，葛楠，林叶，侯晓明

《畜牧兽医学报》

2022

PPARγ-AGPAT6 signaling mediates acetate-induced mTORC1 activation and milk fat synthesis in mammary epithelial cells of dairy cows

Can Liu, Chuanping Liu, Xiaoqing Gong, Yi Hua Jiang, Yang Yang, Jinyou Zhang, Xiaoming Hou, Ye Lin

Journal of Dairy Research

DOI

2021

Cell death-inducing DNA fragmentation factor-α-like effector C (CIDEC) regulates acetate- and β-hydroxybutyrate-induced milk fat synthesis by increasing FASN expression in mammary epithelial cells of dairy cows

He Lv, Qingyu Meng, Nan Wang, Xiaoyu Duan, Xiaoming Hou, Ye Lin

Journal of Dairy Science

DOI

2020

Prolactin regulates LAT1 expression via STAT5 (signal transducer and activator of transcription 5) signaling in mammary epithelial cells of dairy cows

Jinyu Zhou, Minghui Jiang, Ying Shi, Shuyuan Song, Xiaoming Hou, Ye Lin

Journal of Dairy Science

DOI

2020

Examination of methionine stimulation of gene expression in dairy cow mammary epithelial cells using RNA-sequencing

Xiaoming Hou, Minghui Jiang, Jinyu Zhou, Shuyuan Song, Feng Zhao, Ye Lin

Journal of Dairy Research

DOI

2020

Nutrigenomic Role of Acetate and β-Hydroxybutyrate in Bovine Mammary Epithelial Cells

Shuyuan Song, Minghui Jiang, Jinyu Zhou, Feng Zhao, Xiaoming Hou, Ye Lin

DNA and Cell Biology

DOI

2019

Functional analysis of the dairy cow mammary transcriptome between early lactation and mid-dry period

Ye Lin, He Lv, Minghui Jiang, Jinyu Zhou, Shuyuan Song, Xiaoming Hou

Journal of Dairy Research

DOI

2018

奶牛乳脂合成及其影响因素

吕贺，段晓宇，周金玉，宋书媛，姜明慧，侯晓明，林叶

《中国畜牧兽医》

2018

GlyRS is a new mediator of amino acid‐induced milk synthesis in bovine mammary epithelial cells

Chaochao Luo, Hao Qi, Xin Huang, Meng Li, Li Zhang, Ye Lin, Xuejun Gao

Journal of Cellular Physiology

DOI

2017

采用四引物ARMS-PCR方法检测奶牛乳腺组织DGAT1基因单核苷酸多态性

段晓宇，吕贺，杨洋，矫洪涛，侯晓明，林叶

《中国畜牧兽医》

2017

The effects of L-type amino acid transporter 1 on milk protein synthesis in mammary glands of dairy cows

Ye Lin, Xiaoyu Duan, He Lv, Yang Yang, Ying Liu, Xuejun Gao, Xiaoming Hou

Journal of Dairy Science

DOI

2017

Methionine Induces LAT1 Expression in Dairy Cow Mammary Gland by Activating the mTORC1 Signaling Pathway

Xiaoyu Duan, Ye Lin, He Lv, Yang Yang, Hongtao Jiao, Xiaoming Hou

DNA and Cell Biology

DOI

2017

The effects of cell death-inducing DNA fragmentation factor-α-like effector C (CIDEC) on milk lipid synthesis in mammary glands of dairy cows

Yang Yang, Ye Lin, Xiaoyu Duan, He Lv, Weinan Xing, Qingzhang Li, Xuejun Gao, Xiaoming Hou

Journal of Dairy Science

DOI

2016

L型氨基酸转运载体1对奶牛乳腺中β-酪蛋白表达的影响

邢伟楠，段晓宇，杨洋，侯晓明，林叶

《中国畜牧兽医》

2016

The effect of G protein-coupled receptor kinase 2 (GRK2) on lactation and on proliferation of mammary epithelial cells from dairy cows

Xiaoming Hou, Hongliu Hu, Ye Lin, Bo Qu, Xuejun Gao, Qingzhang Li

Journal of Dairy Science

DOI

2016

Spleen tyrosine kinase regulates mammary epithelial cell proliferation in mammary glands of dairy cows

Xiaoming Hou, Lin Lin, Weinan Xing, Yang Yang, Xiaoyu Duan, Qingzhang Li, Xuejun Gao, Ye Lin

Journal of Dairy Science

DOI

2016

Regulation of peroxisome proliferator-activated receptor gamma on milk fat synthesis in dairy cow mammary epithelial cells

Lili Liu, Ye Lin, Lixin Liu, Lina Wang, Yanjie Bian, Xuejun Gao, Qingzhang Li

In Vitro Cellular & Developmental Biology - Animal

DOI

2016

Effects of glucose on lactose synthesis in mammary epithelial cells from dairy cow

Ye Lin, Xiaoxu Sun, Xiaoming Hou, Bo Qu, Xuejun Gao, Qingzhang Li

BMC Veterinary Research

DOI

2016

14-3-3γ regulates cell viability and milk fat synthesis in lipopolysaccharide-induced dairy cow mammary epithelial cells

Lixin Liu, LI ZHANG, Ye Lin, YANJIE BIAN, Xuejun Gao, Bo Qu, Qingzhang Li

Experimental and Therapeutic Medicine

DOI

2016

乳牛における乳汁分泌,及び乳房上皮細胞増殖に及ぼすG蛋白質共役受容体キナーゼ2(GRK2)の影響

Xiao-Ming Hou, Hong-Liu Hu, Ye Lin, B. Qu, Xue-Jun Gao, Qing-zhang Li

2015

miR-142-3p对奶山羊乳腺上皮细胞泌乳功能的影响

Chu-Yue Wang, Chun-Mei Wang, Li Shao, Li Zhang, Ye Lin, Ying-Jun Cui, Xue-Jun Gao, Qing-zhang Li

DOI

2015

脾源性酪氨酸激酶基因在奶牛乳腺中的表达研究

林琳，范会全，邢伟楠，杨洋，侯晓明，张常顺，林叶

《中国畜牧兽医》

2015

脂多糖对奶牛乳腺上皮细胞毒性作用及乳蛋白合成的影响

刘立新，林叶，张莉，李庆章

《东北农业大学学报》

2015

Bta-miR-142-3p对奶牛乳腺上皮细胞泌乳功能的影响

于蕾，王春梅，崔英俊，林叶，张莉，曲波，高学军，李庆章

《中国乳品工业》

2015

14-3-3γ Regulates Lipopolysaccharide-Induced Inflammatory Responses and Lactation in Dairy Cow Mammary Epithelial Cells by Inhibiting NF-κB and MAPKs and Up-Regulating mTOR Signaling

Lixin Liu, Ye Lin, Lili Liu, Yanjie Bian, Li Zhang, Xuejun Gao, Qingzhang Li

International Journal of Molecular Sciences

DOI

2015

Tudor-SN Regulates Milk Synthesis and Proliferation of Bovine Mammary Epithelial Cells

Jinxia Ao, Chengjie Wei, Yu Si, Chaochao Luo, Wei Lv, Ye Lin, Yingjun Cui, Xuejun Gao

International Journal of Molecular Sciences

DOI

2014

小鼠乳腺发育泌乳过程中L型氨基酸转运载体1的表达研究

林叶，胡红柳，侯晓明

《中国畜牧兽医》

2014

必需氨基酸上调乳腺腺泡中L型氨基酸转运载体1的表达

林叶，侯晓明，田雷，齐帮若，李庆章

《中国畜牧兽医》

2014

甲硫氨酸对奶牛乳腺上皮细胞中酪蛋白生物合成的调控

林叶，侯晓明

《中国畜牧杂志》

2014

L型氨基酸转运载体1及其配体在奶牛乳腺中的协同表达研究

林叶，侯晓明

《畜牧兽医学报》

2014

Leucyl-tRNA Synthetase Regulates Lactation and Cell Proliferation via mTOR Signaling in Dairy Cow Mammary Epithelial Cells

Lina Wang, Ye Lin, Yanjie Bian, Lili Liu, Li Shao, Lin Lin, Bo Qu, Feng Zhao, Xuejun Gao, Qingzhang Li

International Journal of Molecular Sciences

DOI

2013

软脂酸对奶牛乳腺上皮细胞甘油三酯合成及脂代谢相关基因表达的影响

刘莉莉，林叶，高学军，李庆章

《中国乳品工业》

2013

王不留行对奶牛乳蛋白合成信号转导通路的影响

孟海洋，孙晓旭，王立娜，林叶，袁肖寒，李庆章，高学军

《中国畜牧兽医》

2013

乳腺泌乳过程中葡萄糖对乳糖合成调控的研究进展

孙晓旭，林叶，高学军，李庆章

《中国乳品工业》

2013

泌乳奶牛乳腺中LAT1和4F2hc的表达定位研究

林叶，侯晓明，李庆章，田雷，闫宏博，李春，黄田英

《中国乳品工业》

2013

Effects of palmitic acid on triacylglycerol synthesis and transcription levels of genes related to fatty metabolism in mammary epithelial cells of dairy cows

L. Lili, Ye Lin, Xue-Jun Gao, Qing-zhang Li

2012

富含赖氨酸和蛋氨酸发酵蛋白饲料制备及其奶牛产奶应用

潘洪宝，高学军，李庆章，王春梅，张莉，林叶

《畜牧与兽医》

2012

奶牛乳腺上皮细胞凋亡周期性规律及机理研究

肖阳，张莉，高学军，王春梅，林叶，李庆章

《畜牧与兽医》

2012

奶牛乳腺上皮细胞E-cadherin/Beta-catenin的定位及表达

童津津，曲波，高学军，王春梅，张莉，林叶，李庆章

《畜牧与兽医》

2012

奶牛乳腺上皮细胞胰岛素样生长因子及受体IGF-ΙR的表达及作用

张童非，崔英俊，高学军，王春梅，张莉，林叶，李庆章

《畜牧与兽医》

2012

小鼠乳腺组织钟基因的筛选与鉴定

齐帮若，高学军，王春梅，张莉，林叶，李庆章

《畜牧与兽医》

2012

催乳素、雌激素和胰岛素对奶牛乳腺上皮细胞中瘦素及其受体的影响

李冬辉，林叶，高学军，王春梅，张莉，李庆章

《畜牧与兽医》

2012

蛋氨酸对奶牛乳腺上皮细胞亚细胞器蛋白质组学影响

王佳丽，高学军，李庆章，王春梅，张莉，林叶

《畜牧与兽医》

2012

乙酸钠和丁酸钠对奶牛乳腺脂肪酸合成相关基因的影响

孔庆洋，林叶，李庆章

《中国乳品工业》

2012

营养素调控奶牛乳蛋白合成的研究进展

毕微微，高学军，林叶，李庆章

《乳业科学与技术》

2011

奶牛不同发育时期乳腺组织LAT1和4F2hc的表达

冯丽丽，林叶，李庆章

《中国乳品工业》

2011

小鼠乳腺上皮细胞培养体系的建立及Heregulin-α的调控作用

耿丽晶，张以涛，林叶，李庆章

《中国科学:生命科学》

2011

奶牛乳腺中瘦素及其受体的表达与定位

郭洪波，林叶，李庆章，边艳杰，肖阳

《中国乳品工业》

2008

中草药防治奶牛(山羊)乳房炎的作用机理及应用前景

齐琳，李庆章，林叶，吕英

《畜牧兽医科技信息》

2007

小鼠乳腺中瘦素及其受体的表达与作用

林叶，李庆章

《中国科学:生命科学》

2006

小鼠乳腺中瘦素的信号转导通路

林叶，李庆章

《东北农业大学学报》

2006

瘦素与乳腺发育和泌乳

林叶，李庆章

《东北农业大学学报》

2005

The Regulation of Development and Lactation of the Mammary Gland by Leptin

Ye Lin, Qing-zhang Li

精选作品

期刊论文

Methionine promotes cell proliferation in bovine mammary epithelial cells via the ATF4-GSK3β signalling pathway

NRF2-CD36 Axis-Mediated Oleic Acid-Induced Milk Fat Production in Dairy Cow Mammary Epithelial Cells

Oxidative stress inhibits milk fat production by p38 MAPK-Cebpα-Acsl6 axis in mouse mammary gland.

CD146基因参与乙酸钠对奶牛乳腺上皮细胞乳脂合成的调节

GPR37L1对奶牛乳腺上皮细胞乳成分合成相关基因表达的影响

MMP23B对奶牛乳腺上皮细胞乳脂合成影响的研究

Prolactin upregulates amino acid uptake in dairy cow mammary epithelial cells via LAT1

Transcriptomic analysis reveals that prolactin modulates the β-casein synthesis mechanism in bovine mammary epithelial cells

Leptin signaling promotes milk fat synthesis via PI3K/AKT/mTOR/SREBP1 in mammary gland of dairy cow

mTORC2‐AKT‐LAT1 signalling participates in methionine‐induced β‐CASEIN expression in mammary epithelial cells of dairy cows

Acetate Upregulates GPR43 Expression and Function via PI3K-AKT-SP1 Signaling in Mammary Epithelial Cells during Milk Fat Synthesis

AGPAT6在奶牛乳腺上皮细胞乳脂合成中的功能研究

奶牛SP1基因结构及对乳脂合成功能的初步分析

PPARγ-AGPAT6 signaling mediates acetate-induced mTORC1 activation and milk fat synthesis in mammary epithelial cells of dairy cows

Cell death-inducing DNA fragmentation factor-α-like effector C (CIDEC) regulates acetate- and β-hydroxybutyrate-induced milk fat synthesis by increasing FASN expression in mammary epithelial cells of dairy cows

Prolactin regulates LAT1 expression via STAT5 (signal transducer and activator of transcription 5) signaling in mammary epithelial cells of dairy cows

Examination of methionine stimulation of gene expression in dairy cow mammary epithelial cells using RNA-sequencing

Nutrigenomic Role of Acetate and β-Hydroxybutyrate in Bovine Mammary Epithelial Cells

Functional analysis of the dairy cow mammary transcriptome between early lactation and mid-dry period

奶牛乳脂合成及其影响因素

GlyRS is a new mediator of amino acid‐induced milk synthesis in bovine mammary epithelial cells

采用四引物ARMS-PCR方法检测奶牛乳腺组织DGAT1基因单核苷酸多态性

The effects of L-type amino acid transporter 1 on milk protein synthesis in mammary glands of dairy cows

Methionine Induces LAT1 Expression in Dairy Cow Mammary Gland by Activating the mTORC1 Signaling Pathway

The effects of cell death-inducing DNA fragmentation factor-α-like effector C (CIDEC) on milk lipid synthesis in mammary glands of dairy cows

L型氨基酸转运载体1对奶牛乳腺中β-酪蛋白表达的影响

The effect of G protein-coupled receptor kinase 2 (GRK2) on lactation and on proliferation of mammary epithelial cells from dairy cows

Spleen tyrosine kinase regulates mammary epithelial cell proliferation in mammary glands of dairy cows

Regulation of peroxisome proliferator-activated receptor gamma on milk fat synthesis in dairy cow mammary epithelial cells

Effects of glucose on lactose synthesis in mammary epithelial cells from dairy cow

14-3-3γ regulates cell viability and milk fat synthesis in lipopolysaccharide-induced dairy cow mammary epithelial cells

乳牛における乳汁分泌,及び乳房上皮細胞増殖に及ぼすG蛋白質共役受容体キナーゼ2(GRK2)の影響

miR-142-3p对奶山羊乳腺上皮细胞泌乳功能的影响

脾源性酪氨酸激酶基因在奶牛乳腺中的表达研究

脂多糖对奶牛乳腺上皮细胞毒性作用及乳蛋白合成的影响

Bta-miR-142-3p对奶牛乳腺上皮细胞泌乳功能的影响

14-3-3γ Regulates Lipopolysaccharide-Induced Inflammatory Responses and Lactation in Dairy Cow Mammary Epithelial Cells by Inhibiting NF-κB and MAPKs and Up-Regulating mTOR Signaling

Tudor-SN Regulates Milk Synthesis and Proliferation of Bovine Mammary Epithelial Cells

小鼠乳腺发育泌乳过程中L型氨基酸转运载体1的表达研究

必需氨基酸上调乳腺腺泡中L型氨基酸转运载体1的表达

甲硫氨酸对奶牛乳腺上皮细胞中酪蛋白生物合成的调控

L型氨基酸转运载体1及其配体在奶牛乳腺中的协同表达研究

Leucyl-tRNA Synthetase Regulates Lactation and Cell Proliferation via mTOR Signaling in Dairy Cow Mammary Epithelial Cells

软脂酸对奶牛乳腺上皮细胞甘油三酯合成及脂代谢相关基因表达的影响

王不留行对奶牛乳蛋白合成信号转导通路的影响

乳腺泌乳过程中葡萄糖对乳糖合成调控的研究进展

泌乳奶牛乳腺中LAT1和4F2hc的表达定位研究

Effects of palmitic acid on triacylglycerol synthesis and transcription levels of genes related to fatty metabolism in mammary epithelial cells of dairy cows

富含赖氨酸和蛋氨酸发酵蛋白饲料制备及其奶牛产奶应用

奶牛乳腺上皮细胞凋亡周期性规律及机理研究

奶牛乳腺上皮细胞E-cadherin/Beta-catenin的定位及表达

奶牛乳腺上皮细胞胰岛素样生长因子及受体IGF-ΙR的表达及作用

小鼠乳腺组织钟基因的筛选与鉴定

催乳素、雌激素和胰岛素对奶牛乳腺上皮细胞中瘦素及其受体的影响

蛋氨酸对奶牛乳腺上皮细胞亚细胞器蛋白质组学影响

乙酸钠和丁酸钠对奶牛乳腺脂肪酸合成相关基因的影响

营养素调控奶牛乳蛋白合成的研究进展

奶牛不同发育时期乳腺组织LAT1和4F2hc的表达

小鼠乳腺上皮细胞培养体系的建立及Heregulin-α的调控作用

奶牛乳腺中瘦素及其受体的表达与定位

中草药防治奶牛(山羊)乳房炎的作用机理及应用前景

小鼠乳腺中瘦素及其受体的表达与作用

小鼠乳腺中瘦素的信号转导通路

瘦素与乳腺发育和泌乳

The Regulation of Development and Lactation of the Mammary Gland by Leptin

会议论文

FABP5 enhances the gene expression of SREBP-1c induced by amino acids and hormones for milk fat synthesis in BMECs

GSK3β通过mTOR/S6K1途径对奶牛乳腺上皮细胞泌乳及增殖的调控

SND1基因对奶牛乳腺上皮细胞泌乳机能的影响

脂肪酸与PPARγ基因互作对奶牛乳腺上皮细胞乳脂肪合成的调节作用及机理

奶牛乳腺上皮细胞核泌乳相关磷酸化蛋白质组学分析

Pten基因对奶牛乳腺上皮细胞泌乳的调节功能

SOCS3抑制STAT5a信号通路调节奶牛乳腺上皮细胞泌乳

miR-152对奶牛乳腺发育和泌乳功能基因Dnmt1的调节作用

Thrsp对奶牛乳腺上皮细胞泌乳功能的影响及其作用机理研究

FABP3基因在奶牛乳腺上皮细胞中的功能研究

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