杜亚楠｜清华大学｜学者主页

2026

Bone marrow-inspired DLL1-presenting microparticles enhance asymmetric division and maintenance of mouse hematopoietic stem and progenitor cells

Wenjing Li, Yi-Ting Feng, Dongbo Han, Yan-Xiao Ao, Michael W. Chen, Ning Li, Yuhong Jin, Hai-Wei Liang, Wen Liu, Xiao-Yu Zhu, Yanan Du

Stem Cell Reports

DOI

2026

Multi-lineage hepatic organoids reveal toxic exosome mediated indirect hepatotoxicity

Lei Sun, Yuying Zhang, Yudi Niu, He Yang, Lyu Zhou, X. Jia, Yihan Chen, Zhi-Qiang Liu, Tian-Tian Wang, Kaini Liang, Dongdong Fan, Si-Da Ling, Zhen Zeng, Yanan Du

Nature Communications

DOI

2026

Viscoelastic hydrogel primed CAR-macrophage for pulmonary fibrosis treatment

Yan Zhang, Zhiqiang Liu, Wenyu Kong, Yan-Xiao Ao, Rui Zhang, Yanan Du

Nature Communications

DOI

2025

Porous microscaffold enables spontaneous hematopoietic cell differentiation and continuous macrophage production from hPSCs for therapy.

Pei-Liang Wang, Hui Qiu, Xia Chen, Wenjing Li, Tian-Jie Li, Xin-Yao Zhou, Danyu Chen, Keng-Yuan Qu, Yaxuan Zhang, Xing-Wu Zhang, Jin-Yang Liu, Yonglin Zhu, Yong-Lin Liang, Haoran An, Shuangyuan Ding, Meng-Da Li, Li Yan, Jian-Ying Guo, Jin-Tao Liu, Yangxin Fu, Jing-Ren Zhang, Yanan Du, Jie Na

Biomaterials

DOI

2025

Corrigendum to "TGase-mediated cell membrane modification and targeted cell delivery to inflammatory endothelium" [Biomaterials, Volume 269, February 2021, 120276].

Chunxiao Qi, Yuhong Jin, Yuyang Chen, Wenjing Li, Ya-Qian Li, Kaini Liang, Yan Li, Yonghui Zhang, Yanan Du

Biomaterials

DOI

2025

Tension-induced directional migration of hepatic stellate cells potentially coordinates liver fibrosis progression

Lyu Zhou, Ziao Shi, Xuesi Yang, Jia'nan Zeng, Zhifeng You, Yuying Zhang, Zhi-Yue Zhu, Zhiqiang Liu, Yudi Niu, Hongsheng Yu, Jinliang He, Yi Long, Zhaozhao Wu, Yan Zhang, Cheng Lyu, Liping Deng, Yuan Wang, Congying Wu, Yanan Du

Nature Biomedical Engineering

DOI

2025

Author Correction: Expansion of human megakaryocyte-biased hematopoietic stem cells by biomimetic Microniche

Ying-Hui Li, Mei He, Wenshan Zhang, Wei Liu, Hui Xu, Ming Yang, Hexiao Zhang, Hai Liang, Wenjing Li, Zhaozhao Wu, W. Fu, Shiqi Xu, Xiaolei Liu, Si-Bin Fan, Liwei Zhou, Chao-Qun Wang, Le-Le Zhang, Yafang Li, Jialin Gu, Jingjing Yin, Yiran Zhang, Yong-Hui Xia, Xuemei Mao, T. Cheng, Jun Shi, Yanan Du, Yingdai Gao

Nature Communications

DOI

2025

Correction: Consistent apparent Young’s modulus of human embryonic stem cells and derived cell types stabilized by substrate stiffness regulation promotes lineage specificity maintenance

Anqi Guo, Bing-ting Wang, Cheng Lyu, Wenjing Li, Yaozu Wu, Lu Zhu, Ran Bi, Chenyu Huang, Jiao-Jiao Li, Yanan Du

Cell Regeneration

DOI

2025

Centimeter‐Scale Self‐Assembling Tendon Organoids Drive Tissue Regeneration

Tianshun Fang, Hong Zhang, Yuanhao Xie, Xiong-Feng Li, Xi Liu, Zi-Cheng Wang, Yiwen Xue, Xiaohui Xia, Ze-Tao Wang, Tingyun Lei, Ruifu Lin, Wei-Liang Shen, Bingbing Wu, Yi-Shan Chen, Yanan Du, Xiao Chen, Zi Yin

Advancement of science

DOI

2025

Hydrogel Microparticle Encapsulation Enhances In Vivo Peptide Delivery of Recombinant Probiotics

Shuang Gao, Kaini Liang, Zejun Fan, Yan-Xiao Ao, Wen Liu, Wenjing Li, Yuanyuan Zhang, Yanan Du

Advanced Functional Materials

DOI

2025

Correction: Image-based evaluation of single-cell mechanics using deep learning

Zhaozhao Wu, Yi-Ting Feng, Ran Bi, Zhiqiang Liu, Yudi Niu, Yuhong Jin, Wenjing Li, Huijun Chen, Yan Shi, Yanan Du

Cell Regeneration

DOI

2025

Image-based evaluation of single-cell mechanics using deep learning

Zhaozhao Wu, Yi-Ting Feng, Ran Bi, Zhiqiang Liu, Yudi Niu, Yuhong Jin, Wenjing Li, Huijun Chen, Yan Shi, Yanan Du

Cell Regeneration

DOI

2025

hESCs‐derived Organoids Achieve Liver Zonation Features through LSEC Modulation

Yuying Zhang, Chen-Yan Huang, Lei Sun, Lyu Zhou, Yudi Niu, Kaini Liang, Bing-Jie Wu, Peng Zhao, Zhiqiang Liu, Xiaolin Zhou, Peng Zhang, Jianchen Wu, Jie Na, Yanan Du

Advancement of science

DOI

2025

Growing meat on autoclaved vegetables with biomimetic stiffness and micro-patterns

Ye Liu, Anqi Gao, Tian-Tian Wang, Yong-Qian Zhang, Gao-Xiang Zhu, Si-Da Ling, Zhaozhao Wu, Yuhong Jin, Haoke Chen, Yuming Lai, Rui Zhang, Yu-Chen Yang, Jian-Yong Han, Yulin Deng, Yanan Du

Nature Communications

DOI

2025

Fiber recruitment drives a phase transition of cell polarization at a critical cell spacing in matrix-mediated tissue remodeling

Xiang-Jun Peng, Yuxuan Huang, Wenyu Kong, Yanan Du, E. Elson, Xi-Qiao Feng, Guy M. Genin

Proceedings of the National Academy of Sciences of the United States of America

DOI

2025

Corrigendum to “Modulating immune responses for enhanced cell therapies: the dual role of multi-scale biomaterials” [EngMedicine 1 (2024) 100038]

Jia'nan Zeng, Yuhong Jin, Yan-Xiao Ao, Wenjing Li, Kaini Liang, Haoke Chen, Yi Long, Yanan Du

EngMedicine

DOI

2025

Artificial cells with liquid–liquid phase separation–regulated cell-free protein synthesis

Dongdong Fan, Kaini Liang, Bing-Jie Wu, Michael W. Chen, Chengyu Sun, Lei Sun, Yan Zhang, Yanan Du

Proceedings of the National Academy of Sciences of the United States of America

DOI

2025

Chemo-mechanotherapy of fibrosis: dynamic control of biological materials through tissue-architecture-dependent crosslink disruption

Wenyu Kong, Mei-Yue Song, Xiang-Jun Peng, Lu Bai, Jia'nan Zeng, Kaini Liang, Yuhong Jin, Jia-Xin Wang, Xue Wang, Yuxuan Huang, Yudi Niu, Lyu Zhou, Xi-Qiao Feng, Chen Wang, Guy M. Genin, Jing Wang, Yanan Du

bioRxiv

DOI

2025

Corrigendum to ‘Pathology-targeted cell delivery via injectable micro-scaffold capsule mediated by endogenous TGase’ [Biomaterials, 126 (2017), 17950]

Chunxiao Qi, Yaqian Li, Patrick A Badger, Hongsheng Yu, Zhifeng You, Xiaojun Yan, Wei Liu, Yan Shi, Tie Xia, Jiahong Dong, Chenyu Huang, Yanan Du

Biomaterials

DOI

2025

Gelatin sponge patch grafting of microcryogel-based three-dimensional mesenchymal stem cells to alleviate acute liver failure

Haimeng Song, Xinyue Du, Yuanyuan Zhang, Wei Liu, Yi Luo, Yuxin Liu, Yupeng Xue, Mingyang Xu, Ji‐Zhen Lu, Ji‐Zhen Lu, Wenwen Jia, Yanan Du, Lining Cao, Jianfeng Lu, Jianfeng Lu, Wencheng Zhang, Zhiying He

Biomaterials

DOI

2025

Correction: Magnetically controllable 3D microtissues based on magnetic microcryogels

Wei Liu, Yaqian Li, Siyu Feng, Ning Jia, Jingyu Wang, Maling Gou, Huijun Chen, Feng Xu, Yanan Du

Lab on a Chip

DOI

2025

Hepatic hypertension on-a-chip identifies GPR116 as a hydrostatic pressure mechanosensor to regulate vascular injury in cirrhosis

Yi Long, Kaini Liang, Yudi Niu, Rui Wang, Ruiquan Liu, Yan Zhang, Yanxiao Ao, Yuhong Jin, Zhaozhao Wu, Bingjie Wu, Zhiqiang Liu, Xin Zhang, Xiangyu Liu, Xiaolong Qi, Bin Liu, Yanan Du

Science Advances

DOI

2025

Cortical Actin Depolymerisation in 3D Cell Culture Enhances Extracellular Vesicle Secretion and Therapeutic Effects

Zhen Yang, Xiaoke Li, Qiyuan Lin, Fanfan Zhou, Kaini Liang, Jiao Jiao Li, Yudi Niu, Qingchen Meng, Tianyuan Zhao, Hao Li, Du Wang, Jianjing Lin, Jianjing Lin, Hui Li, Bin Wang, Wei Liu, Yanan Du, Jianhao Lin, Jianhao Lin, Dan Xing

Journal of Extracellular Vesicles

DOI

2025

Correction to “Sequential Assembly of Cell‐Laden Hydrogel Constructs to Engineer Vascular‐Like Microchannels”

Yanan Du, Majid Ghodousi, Hao Qi, Nikhil Haas, Wenqian Xiao, Ali Khademhosseini

Biotechnology and Bioengineering

DOI

2025

3D Mechanical Response Stem Cell Complex Repairs Spinal Cord Injury by Promoting Neurogenesis and Regulating Tissue Homeostasis

Jingwei Jiu, Haifeng Liu, Dijun Li, Xiaoke Li, Jing Zhang, Lei Yan, Zijuan Fan, Songyan Li, Guangyuan Du, Jiao Jiao Li, Aimin Wu, Wei Liu, Yanan Du, Bin Zhao, Bin Wang

Advanced Healthcare Materials

DOI

2024

MICROFLUIDIC-PREPARATION OF VISCOELATIC MICROFIBER FOR ENHANCED FABRICATION OF ARTIFICIAL MEAT

Si-Da Ling, Wenjun Ma, Ying-Zhe Liu, Yanan Du, Zhuo Chen, Jian-Hong Xu

2024 MicroTAS Book of Abstracts

DOI

2024

Viscoelasticity of ECM and cells—origin, measurement and correlation

Zhiqiang Liu, Si-Da Ling, Kaini Liang, Yihan Chen, Yudi Niu, Lei Sun, Jun-Yang Li, Yanan Du

Mechanobiology in medicine

DOI

2024

Modulating immune responses for enhanced cell therapies: The dual role of multi-scale biomaterials

Jia'nan Zeng, Yuhong Jin, Yan-Xiao Ao, Wenjing Li, Kaini Liang, Haoke Chen, Yi Long, Yanan Du

EngMedicine

DOI

2024

Superimposed Electric Field Enhanced Electrospray for High‐Throughput and Consistent Cell Encapsulation

Zejun Fan, Yihan Chen, Zhen Yang, Yudi Niu, Kaini Liang, Yan Zhang, Jia'nan Zeng, Yi-Ting Feng, Yuying Zhang, Ye Liu, Chengwei Lv, Peng Zhao, Lv Zhou, Wenyu Kong, Wenjing Li, Haoke Chen, Dongbo Han, Yanan Du

Advanced Healthcare Materials

DOI

2024

Water Transport‐Induced Liquid–Liquid Phase Separation Facilitates Gelation for Controllable and Facile Fabrication of Physically Crosslinked Microgels

Michael W. Chen, Dongdong Fan, Xiang-Jiang Liu, Dongbo Han, Yuhong Jin, Yan-Xiao Ao, Yuyang Chen, Zhiqiang Liu, Yi-Ting Feng, Si-Da Ling, Kaini Liang, Wenyu Kong, Jian-Hong Xu, Yanan Du

Advances in Materials

DOI

2024

Exosomes derived from 3D-cultured MSCs alleviate knee osteoarthritis by promoting M2 macrophage polarization through miR-365a-5p and inhibiting TLR2/Myd88/NF-κB pathway

Lei Yan, Dijun Li, Songyan Li, Jiao Jiao Li, Guangyuan Du, Haifeng Liu, Jing Zhang, Xiaoke Li, Zijuan Fan, Jingwei Jiu, Ruoqi Li, Jingwei Jiu, Wei Liu, Yanan Du, Bin Wang

Chemical Engineering Journal

DOI

2024

Tissue-engineered mesenchymal stem cell constructs alleviate tendinopathy by suppressing vascularization

Dijun Li, Jingwei Jiu, Haifeng Liu, Xiaojun Yan, Xiaoke Li, Lei Yan, Jing Zhang, Zijuan Fan, Songyan Li, Guangyuan Du, Jiao Jiao Li, Yanan Du, Wei Liu, Bin Wang

Bioactive Materials

DOI

2023

Advanced glycation end-products as mediators of the aberrant crosslinking of extracellular matrix in scarred liver tissue

Cheng Lyu, Wenyu Kong, Zhiqiang Liu, Sihan Wang, Peng Zhao, Kaini Liang, Yudi Niu, Wei Yang, Canhong Xiang, Xiaoyu Hu, Xue-Ming Li, Yanan Du

Nature Biomedical Engineering

DOI

2023

Gelatin-based 3D biomimetic scaffolds platform potentiates culture of cancer stem cells in esophageal squamous cell carcinoma.

Yenan Wu, Haiwei Liang, Ai-Ping Luo, Yong Li, Zhiqiang Liu, Xin Li, Wenxin Li, Kaini Liang, Jun Yu Li, Zhi-Hua Liu, Yanan Du

Biomaterials

DOI

2023

Biophysical cues of bone marrow-inspired scaffolds regulate hematopoiesis of hematopoietic stem and progenitor cells.

Wenjing Li, Haiwei Liang, Yanxiao Ao, Baixue Tang, Jun Yu Li, Ning Li, Jianwei Wang, Yanan Du

Biomaterials

DOI

2023

Response to a Comment on “Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis”

Penghui Zhao, Tian Sun, Cheng Lyu, Yanan Du

Advancement of science

DOI

2023

Enhanced bone regeneration via endochondral ossification using Exendin-4-modified mesenchymal stem cells

Zihao He, Hui Li, Yuanyuan Zhang, Shuang Gao, Kaini Liang, Yiqi Su, Yanan Du, Du Wang, D. Xing, Zhen Yang, Jian-Hao Lin

Bioactive Materials

DOI

2023

Cell mediated ECM-degradation as an emerging tool for anti-fibrotic strategy

Penghui Zhao, Tian Sun, Cheng Lyu, Kaini Liang, Yanan Du

Cell Regeneration

DOI

2023

Transglutaminase-crosslinked extracellular matrix in cirrhotic liver tissues provides pro-fibrotic mechano-microenvironment for cells

Cheng Lyu, Wenyu Kong, Yan Zhang, Zhiqiang Liu, Kaini Liang, Yanan Du

Life Medicine

DOI

2023

In situ self-assembled organoid for osteochondral tissue regeneration with dual functional units.

Zhen Yang, Bin Wang, Wei Liu, Xiao-Ke Li, Kaini Liang, Zejun Fan, Jiao-Jiao Li, Yudi Niu, Zihao He, Hui Li, Du Wang, Jian-Jing Lin, Yanan Du, Jian-Hao Lin, D. Xing

Bioactive Materials

DOI

2023

Expansion of human megakaryocyte-biased hematopoietic stem cells by biomimetic Microniche

Ying-Hui Li, Mei He, Wenshan Zhang, Wei Liu, Hui Xu, Ming Yang, Hexiao Zhang, Haiwei Liang, Wenjing Li, Zhaozhao Wu, W. Fu, Shiqi Xu, Xiaolei Liu, Si-Bin Fan, Liwei Zhou, Chao-Qun Wang, Le-Le Zhang, Yafang Li, J. Gu, Jingjing Yin, Yiran Zhang, Yong-Hui Xia, Xuemei Mao, T. Cheng, Jun Shi, Yanan Du, Yingdai Gao

Nature Communications

DOI

2023

Large-Scale Cell Production Based on GMP-Grade Dissolvable Porous Microcarriers.

Yuyang Chen, Huanye Xu, Yuanyuan Zhang, Leilei Guo, Miaomiao Lan, Yan-Ping Yang, Wei Liu, Xiao-Jun Yan, Yanan Du

Journal of Visualized Experiments

DOI

2022

Engineered meatballs via scalable skeletal muscle cell expansion and modular micro-tissue assembly using porous gelatin micro-carriers.

Ye Liu, Ruixia Wang, Shi-Jie Ding, Li Deng, Yuanyuan Zhang, Jun Yu Li, Ziao Shi, Zhongyuan Wu, Kaini Liang, Xiao-Jun Yan, Wei Liu, Yanan Du

Biomaterials

DOI

2022

Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis

Penghui Zhao, Tian Sun, Cheng Lyu, Kaini Liang, Yudi Niu, Yuying Zhang, Chenhui Cao, Can-Hong Xiang, Yanan Du

Advancement of science

DOI

2022

Precise cell therapy for liver fibrosis: Endothelial cell and macrophage therapy

Li-Ping Deng, Bing-Jie Wu, Kaini Liang, Hongen Liao, Yanan Du

iLiver

DOI

2022

Injectable bone marrow microniches by co-culture of HSPCs with MSCs in 3D microscaffolds promote hematopoietic reconstitution from acute lethal radiation

Haiwei Liang, Yanxiao Ao, Wenjing Li, Kaini Liang, Baixue Tang, Jun Yu Li, Jianwei Wang, Xiaoyu Zhu, Yanan Du

Bioactive Materials

DOI

2022

3D biomaterial P scaffolds carrying umbilical cord mesenchymal stem cells improve biointegration of keratoprosthesis

Yueyue Li, Wenqin Xu, Qian Li, Xiaoqi Li, Jun Yu Li, L. Kang, Yi-Fan Fang, Shuaishuai Cheng, Penghui Zhao, Shu-Meng Jiang, Wei Liu, Xiao-Jun Yan, Yanan Du, Li-Qiang Wang, Yifei Huang

Biomedical Materials

DOI

2022

Mesenchymal Stem Cells (MSCs): A Novel Therapy for Type 2 Diabetes

Shuang Gao, Yuanyuan Zhang, Kaini Liang, Ran Bi, Yanan Du

Stem Cells International

DOI

2022

GMP‐grade microcarrier and automated closed industrial scale cell production platform for culture of MSCs

Yuanyuan Zhang, Tao Na, Ke-Hua Zhang, Yan-Ping Yang, Huanye Xu, Li-Na Wei, Liming Xu, Xiao-Jun Yan, Wei Liu, Guangyang Liu, Bin Wang, S. Meng, Yanan Du

Journal of Tissue Engineering and Regenerative Medicine

DOI

2022

A Novel Step-T-Junction Microchannel for the Cell Encapsulation in Monodisperse Alginate-Gelatin Microspheres of Varying Mechanical Properties at High Throughput

Si-Da Ling, Zhiqiang Liu, Wen-Di Ma, Zhuo Chen, Yanan Du, Jianhong Xu

Biosensors

DOI

2022

Research progress of stem cell therapy for endometrial injury

Juan Cen, Yichen Zhang, Yindu Bai, Shenqian Ma, Chuan Zhang, Lin Jin, Shaofeng Duan, Yanan Du, Yuqi Guo

Materials Today Bio

DOI

2022

Generation of monodisperse micro-droplets within the stable narrowing jetting regime: effects of viscosity and interfacial tension

Si Da Ling, Jingwei Zhang, Zhuo Chen, Wenjun Ma, Yanan Du, Jianhong Xu

Microfluidics and Nanofluidics

DOI

2021

Targeted cell therapy for partial-thickness cartilage defects using membrane modified mesenchymal stem cells by transglutaminase 2.

Hui Li, Yuting Jin, Yu Zhao, Wenjing Li, Zihao He, Qing-Xi Zhang, Hesuyuan Huang, Jian-Jing Lin, Yuyang Chen, D. Xing, Yanan Du, Jian-Hao Lin

Biomaterials

DOI

2021

Cell engineering techniques improve pharmacology of cellular therapeutics

Kaini Liang, Yanan Du

Biomaterials and Biosystems

DOI

2021

Efficient endothelial and smooth muscle cell differentiation from human pluripotent stem cells through a simplified insulin-free culture system.

Feng-Zhi Zhang, Yonglin Zhu, J. Chen, Wenhua Kuang, Rujin Huang, Fuyu Duan, Yaqian Li, Lin Wang, Hui Qiu, Xia Chen, Ming Jia, Peng Liu, Yanan Du, S. Chang, Ligong Chen, Jie Na

Biomaterials

DOI

2021

Mechanical communication in fibrosis progression.

Y. Long, Yudi Niu, Kaini Liang, Yanan Du

Trends in Cell Biology

DOI

2021

Key considerations on the development of biodegradable biomaterials for clinical translation of medical devices: With cartilage repair products as an example

Li Wang, Xiao-Lei Guo, Jiaqing Chen, Zhen Zhen, B. Cao, Wenqian Wan, Yuan-Dong Dou, H. Pan, Feng Xu, Zepu Zhang, Jian-Mei Wang, Daisong Li, Quan-Yi Guo, Qing Jiang, Yanan Du, Jia-Kuo Yu, Bo-On C. Heng, Qianqian Han, Z. Ge

Bioactive Materials

DOI

2021

Collagen crosslinking: effect on structure, mechanics and fibrosis progression

Wenyu Kong, Cheng Lyu, Hongen Liao, Yanan Du

Biomedical Materials

DOI

2021

Asporin inhibits collagen matrix‐mediated intercellular mechanocommunications between fibroblasts during keloid progression

Long-Wei Liu, Hong-Sheng Yu, Y. Long, Zhifeng You, R. Ogawa, Yanan Du, Chenyu Huang

The FASEB Journal

DOI

2021

A low dose cell therapy system for treating osteoarthritis: In vivo study and in vitro mechanistic investigations

Bin Wang, Wei Liu, Jiao-Jiao Li, S. Chai, D. Xing, Hong-Sheng Yu, Yuanyuan Zhang, Wen-Jin Yan, Zhi-Hong Xu, Bin Zhao, Yanan Du, Qing Jiang

Bioactive Materials

DOI

2021

Synthetic liver fibrotic niche extracts achieve in vitro hepatoblasts phenotype enhancement and expansion

Yuying Zhang, Anqi Guo, Cheng Lyu, Ran Bi, Zhaozhao Wu, Wenjing Li, Penghui Zhao, Yudi Niu, Jie Na, J. Xi, Yanan Du

iScience

DOI

2021

Exendin-4 gene modification and microscaffold encapsulation promote self-persistence and antidiabetic activity of MSCs

Yuanyuan Zhang, Shuang Gao, Kaini Liang, Zhaozhao Wu, Xiao-Jun Yan, Wei Liu, Jun-Yang Li, Bingjie Wu, Yanan Du

Science Advances

DOI

2021

Large-Scale Expansion of Umbilical Cord Mesenchymal Stem Cells with Microcarrier Tablets in Bioreactor.

Huanye Xu, Zhongxiao Cong, Yuanyuan Zhang, Wei Liu, Xiao-Jun Yan, Yanan Du

Methods in molecular biology

DOI

2020

TGase-mediated cell membrane modification and targeted cell delivery to inflammatory endothelium.

Chunxiao Qi, Yu-Hong Jin, Yuyang Chen, Wenjing Li, Ya-Qian Li, Kai Liang, Yan Li, Yonghui Zhang, Yanan Du

Biomaterials

DOI

2020

Dispersible and Dissolvable Porous Microcarrier Tablets Enable Efficient Large-Scale Human Mesenchymal Stem Cell Expansion

Xiao-Jun Yan, Kun Zhang, Yan-Ping Yang, D. Deng, Cheng Lyu, Huanye Xu, Wei Liu, Yanan Du

Tissue Engineering. Part C, Methods

DOI

2020

Functional Nanoparticles Activate a Decellularized Liver Scaffold for Blood Detoxification.

Fen Xu, Tian-Yi Kang, Jie Deng, Junli Liu, Xiaolei Chen, Yuan Wang, L. Ouyang, Ting Du, Hong Tang, Xiao-Ping Xu, Shaochen Chen, Yanan Du, Yu-Jun Shi, Z. Qian, Yu-Quan Wei, H. Deng, Ma-Ling Gou

Small

DOI

2020

Enhanced single-cell encapsulation in microfluidic devices: From droplet generation to single-cell analysis.

Si-Da Ling, Yu-Hao Geng, An Chen, Yanan Du, Jianhong Xu

Biomicrofluidics

DOI

2020

Engineering 3D functional tissue constructs using self-assembling cell-laden microniches.

D. Xing, Wei Liu, Jiao-Jiao Li, Long-Wei Liu, Anqi Guo, Bin Wang, Hong-Sheng Yu, Yu Zhao, Yuling Chen, Zhifeng You, Cheng Lyu, Wenjing Li, Ai-Feng Liu, Yanan Du, Jianhao Lin

Acta Biomaterialia

DOI

2020

Construction of Microunits by Adipose-Derived Mesenchymal Stem Cells Laden with Porous Microcryogels for Repairing an Acute Achilles Tendon Rupture in a Rat Model

Xuan Yang, H. Meng, Jiang Peng, Li-Juan Xu, Yu wangW, Xun Sun, Yan-Xu Zhao, Qi Quan, Wen Yu, Ming-Xue Chen, Tong Shi, Yanan Du, Shi-Bi Lu, Ai-Yuan Wang

International Journal of Nanomedicine

DOI

2020

Matrix-transmitted paratensile signaling enables myofibroblast–fibroblast cross talk in fibrosis expansion

Long-Wei Liu, Hong-Sheng Yu, Hui Zhao, Zhaozhao Wu, Y. Long, Jingbo Zhang, Xiao-Jun Yan, Zhifeng You, Lyu Zhou, Tie Xia, Yan Shi, Bai-Long Xiao, Ying-Xiao Wang, Chenyu Huang, Yanan Du

Proceedings of the National Academy of Sciences of the United States of America

DOI

2020

Consistent apparent Young’s modulus of human embryonic stem cells and derived cell types stabilized by substrate stiffness regulation promotes lineage specificity maintenance

Anqi Guo, Bing-jie Wang, Cheng Lyu, Wenjing Li, Yaozu Wu, Lu Zhu, Ran Bi, Chenyu Huang, Jiao-Jiao Li, Yanan Du

Cell Regeneration

DOI

2020

TGase‐Enhanced Microtissue Assembly in 3D‐Printed‐Template‐Scaffold (3D‐MAPS) for Large Tissue Defect Reparation

Hong-Sheng Yu, Zhifeng You, Xiao-Jun Yan, Wei Liu, Zhirui Nan, D. Xing, Chenyu Huang, Yanan Du

Advanced Healthcare Materials

DOI

2020

Comparison of Chondrocytes in Knee Osteoarthritis and Regulation by Scaffold Pore Size and Stiffness

Yu Zhao, Zhifeng You, D. Xing, Jiao-Jiao Li, Qing-Xi Zhang, Hesuyuan Huang, Zhikun Li, Shu-Meng Jiang, Zhaozhao Wu, Yuying Zhang, Wenjing Li, Lin Zhang, Yanan Du, Jianhao Lin

Tissue Engineering. Part A

DOI

2020

Bottom‐up Tissue Engineering: TGase‐Enhanced Microtissue Assembly in 3D‐Printed‐Template‐Scaffold (3D‐MAPS) for Large Tissue Defect Reparation (Adv. Healthcare Mater. 18/2020)

Hong-Sheng Yu, Zhifeng You, Xiao-Jun Yan, Wei Liu, Zhirui Nan, D. Xing, Chenyu Huang, Yanan Du

Advanced Healthcare Materials

DOI

2020

Intra-articular Injection of Cell-laden 3D Microcryogels Empower Low-dose Cell Therapy for Osteoarthritis in a Rat Model

D. Xing, Wei Liu, Bin Wang, Jiao-Jiao Li, Yu Zhao, Hui Li, Ai-Feng Liu, Yanan Du, Jianhao Lin

Cell Transplantation

DOI

2019

High throughput scaffold-based 3D micro-tumor array for efficient drug screening and chemosensitivity testing.

Xiao-Jun Yan, Lyu Zhou, Zhaozhao Wu, Xun Wang, Xiuyu Chen, Fan Yang, Yanan Guo, Min Wu, Yuyang Chen, Wenjing Li, Jun Wang, Yanan Du

Biomaterials

DOI

2019

Injectable nanohydroxyapatite-chitosan-gelatin microscaffolds induce regeneration of knee subchondral bone cyst-like lesions

Bin Wang, Wei Liu, D. Xing, Yanan Du, Jiu-Xiang Lin

Osteoarthritis and Cartilage

DOI

2019

Evaluation of intervertebral disc regeneration with injection of mesenchymal stem cells encapsulated in PEGDA-microcryogel delivery system using quantitative T2 mapping: a study in canines.

Jinwei Ying, Zhi-Hua Han, Yang Zeng, Yanan Du, Shishen Pei, Linghao Su, Dike Ruan, Chun Chen

American journal of translational research

2019

Mechanical microenvironment as a key cellular regulator in the liver

Zhifeng You, Lyu Zhou, Wenjing Li, Chenyu Huang, Yanan Du

Acta Mechanica Sinica

DOI

2019

Cryoprotectant enables structural control of porous scaffolds for exploration of cellular mechano-responsiveness in 3D

Shu-Meng Jiang, Cheng Lyu, Peng Zhao, Wenjing Li, Wenyu Kong, Chenyu Huang, G. Genin, Yanan Du

Nature Communications

DOI

2019

Evaluation of intervertebral disc regeneration with injection of mesenchymal stem cells encapsulated in PEGDA-microcryogel delivery system using quantitative T2 mapping: a study in canines.

Jinwei Ying, Zhihua Han, Yang C. Zeng, Yanan Du, Shishen Pei, Linghao Su, Dike Ruan, Chun Chen

PubMed

2018

Physical Properties of Implanted Porous Bioscaffolds Regulate Skin Repair: Focusing on Mechanical and Structural Features

Shu-Meng Jiang, Sabrina Cloud Li, Chenyu Huang, B. Chan, Yanan Du

Advanced Healthcare Materials

DOI

2017

Pathology-targeted cell delivery via injectable micro-scaffold capsule mediated by endogenous TGase.

Chunxiao Qi, Yaqian Li, Patrick A. Badger, Hong-Sheng Yu, Zhifeng You, Xiao-Jun Yan, Wei Liu, Yan Shi, Tie Xia, Jia-Hong Dong, Chenyu Huang, Yanan Du

Biomaterials

DOI

2017

Mechanically and Electrically Enhanced CNT-Collagen Hydrogels As Potential Scaffolds for Engineered Cardiac Constructs.

Hong-Sheng Yu, H Zhao, Chenyu Huang, Yanan Du

ACS Biomaterials Science & Engineering

DOI

2017

Biomechanically primed liver microtumor array as a high-throughput mechanopharmacological screening platform for stroma-reprogrammed combinatorial therapy.

Lu Zhu, Xing-Liang Fan, Bing-Jie Wang, Long-Wei Liu, Xiao-Jun Yan, Lyu Zhou, Yang Zeng, M. Poznansky, Li-Li Wang, Hua-Biao Chen, Yanan Du

Biomaterials

DOI

2017

Mechanotransduction-modulated fibrotic microniches reveal the contribution of angiogenesis in liver fibrosis.

Long-Wei Liu, Zhifeng You, Hong-Sheng Yu, Lyu Zhou, Hui Zhao, Xiao-Jun Yan, Dulei Li, Bing-Jie Wang, Lu Zhu, Yuzhou Xu, Tie Xia, Yan Shi, Chenyu Huang, Wei Hou, Yanan Du

Nature Materials

DOI

2017

Stiffness‐Controlled Thermoresponsive Hydrogels for Cell Harvesting with Sustained Mechanical Memory

Xing-Liang Fan, Lu Zhu, Ke Wang, Bing-Jie Wang, Yaozu Wu, Wei Xie, Cheng-Yu Huang, B. Chan, Yanan Du

Advanced Healthcare Materials

DOI

2017

Injectable Gelatin-chitosan-hydroxyapatitemicro-cryogels Enabling Stem Cell Osteogenic Differentiation and Accelerating Theregeneration of Subchondral Bone Cyst

Bin Wang, Wei Liu, D. Xing, Ying-Feng Li, R. Li, Yanan Du, Jiu-Xiang Lin

DOI

2017

幹細胞リプログラミング組合せ療法のためのハイスループットmechanopharmacologicalスクリーニングプラットフォームとしての生体力学的感作された肝しゅようアレイ【Powered by NICT】

Lu Zhu, Xing-Liang Fan, Bing-Jie Wang, Long-Wei Liu, Xiao-Jun Yan, Zhou Lyu, Yang Zeng, C. Mark, Li-Li Wang, Hua-Biao Chen, Yanan Du

2017

Optimizing mesoderm progenitor selection and three-dimensional microniche culture allows highly efficient endothelial differentiation and ischemic tissue repair from human pluripotent stem cells

Feng-Zhi Zhang, Lin Wang, Yaqian Li, Wei Liu, Fuyu Duan, Rujin Huang, Xi Chen, S. Chang, Yanan Du, Jie Na

Stem cell research & therapeutics

DOI

2017

Keloid progression: a stiffness gap hypothesis

Chenyu Huang, Long-Wei Liu, Zhifeng You, Bing-Jie Wang, Yanan Du, R. Ogawa

International Wound Journal

DOI

2017

Endothelial dysfunction and mechanobiology in pathological cutaneous scarring: lessons learned from soft tissue fibrosis

Chenyu Huang, Long-Wei Liu, Zhifeng You, Yu-Fen Zhao, Jiahong Dong, Yanan Du, R. Ogawa

British Journal of Dermatology

DOI

2017

Preconditioning of mesenchymal stromal cells toward nucleus pulposus-like cells by microcryogels-based 3D cell culture and syringe-based pressure loading system.

Yang Zeng, Siyu Feng, Wei Liu, Qinyouen Fu, Yaqian Li, Xiaokang Li, Chun Chen, Chenyu Huang, Z. Ge, Yanan Du

Journal of Biomedical Materials Research. Part B - Applied biomaterials

DOI

2017

Additional file 2: Table S2. of Optimizing mesoderm progenitor selection and three-dimensional microniche culture allows highly efficient endothelial differentiation and ischemic tissue repair from human pluripotent stem cells

Feng-Zhi Zhang, Lin Wang, Yaqian Li, Wei Liu, Fuyu Duan, Rujin Huang, Xi Chen, S. Chang, Yanan Du, Jie Na

DOI

2017

3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening.

Yaqian Li, Xiao-Jun Yan, Wei Liu, Lyu Zhou, Zhifeng You, Yanan Du

Journal of Visualized Experiments

DOI

2017

Preferential sensing and response to microenvironment stiffness of human dermal fibroblast cultured on protein micropatterns fabricated by 3D multiphoton biofabrication

M. Tong, N. Huang, A. Ngan, Yanan Du, B. Chan

Scientific Reports

DOI

2017

Injectable nanohydroxyapatite-chitosan-gelatin micro-scaffolds induce regeneration of knee subchondral bone lesions

B Wang, W Liu, Dan Xing, R Li, C. Lv, Ying Li, X. Yan, Yan Ke, Y. Xu, Yanan Du, Jianhao Lin

Scientific Reports

DOI

2016

Engineering EMT using 3D micro-scaffold to promote hepatic functions for drug hepatotoxicity evaluation.

Jingyu Wang, Fengling Chen, Long-Wei Liu, Chunxiao Qi, Bing-Jie Wang, Xiao-Jun Yan, Chenyu Huang, Wei Hou, Michael Q. Zhang, Yang Chen, Yanan Du

Biomaterials

DOI

2016

Physically entrapped gelatin in polyethylene glycol scaffolds for three-dimensional chondrocyte culture

Jingjing Zhang, A. Mujeeb, Jun-Xia Feng, Yi-Jiang Li, Yanan Du, Jianhao Lin, Z. Ge

DOI

2016

Temperature-sensitive polymer material with adjustable hardness and preparation method and application thereof

Yanan Du, Xing-Liang Fan, Lu Zhu, Bing-Jie Wang

2016

Regeneration of hair and other skin appendages: A microenvironment‐centric view

Chenyu Huang, Yanan Du, C. Nabzdyk, R. Ogawa, Taro Koyama, D. Orgill, Xiao-Bing Fu

Wound Repair and Regeneration

DOI

2016

Multiphoton photochemical crosslinking-based fabrication of protein micropatterns with controllable mechanical properties for single cell traction force measurements

M. Tong, N. Huang, Wei Zhang, Zhuo-Long Zhou, A. Ngan, Yanan Du, B. Chan

Scientific Reports

DOI

2016

Substrate stiffness orchestrates epithelial cellular heterogeneity with controlled proliferative pattern via E-cadherin/β-catenin mechanotransduction.

Bing-Jie Wang, Peng Qin, Hui Zhao, Tie Xia, Jingyu Wang, Long-Wei Liu, Lu Zhu, Jing Xu, Chenyu Huang, Yan Shi, Yanan Du

Acta Biomaterialia

DOI

2016

Mechanobiology and Mechanotherapy for Cutaneous Wound‐Healing

Chenyu Huang, Yanan Du, R. Ogawa

DOI

2016

Functional Nanoparticles Activate a Decellularized Liver Scaffold for Blood Detoxification.

Fen Xu, Tian-Yi Kang, Jie Deng, Junli Liu, Xiaolei Chen, Y. Wang, L. Ouyang, Ting Du, Hong Tang, Xiao-Ping Xu, Shaochen Chen, Yanan Du, Yu-Jun Shi, Z. Qian, Yu-Quan Wei, H. Deng, Ma-Ling Gou

Small

DOI

2016

3D-engineering of Cellularized Conduits for Peripheral Nerve Regeneration

Yu Hu, Yao Wu, Zhiyuan Gou, J. Tao, Jiu-Meng Zhang, Qian-Qi Liu, Tian-Yi Kang, Shu Jiang, Siqing Huang, Jian-Kang He, Shaochen Chen, Yanan Du, Ma-Ling Gou

Scientific Reports

DOI

2016

Method for preparing artificial microenvironment and application thereof

Yanan Du, Yaqian Li, Shu-Meng Jiang

2015

A ready-to-use, versatile, multiplex-able three-dimensional scaffold-based immunoassay chip for high throughput hepatotoxicity evaluation.

Xiao-Jun Yan, Jingyu Wang, Lu Zhu, J. Lowrey, Yuanyuan Zhang, Wei Hou, Jia-Hong Dong, Yanan Du

Lab on a Chip

DOI

2015

Injectable microcryogels reinforced alginate encapsulation of mesenchymal stromal cells for leak-proof delivery and alleviation of canine disc degeneration.

Yang Zeng, Chun Chen, Wei Liu, Qinyouen Fu, Zhi-Hua Han, Yaqian Li, Siyu Feng, Xiaokang Li, Chunxiao Qi, Jianhong Wu, De-Li Wang, Christopher Corbett, B. Chan, Dike Ruan, Yanan Du

Biomaterials

DOI

2015

Bi-content micro-collagen chip provides contractility-based biomechanical readout for phenotypic drug screening with expanded and profiled targets.

Hui Zhao, Lyu Zhou, Qiang Zhang, Xiao-Ying Zhou, Yonghui Zhang, Huijun Chen, Yanan Du

Lab on a Chip

DOI

2015

Engineering Embryonic Stem Cell Microenvironments for Tailored Cellular Differentiation

Chenyu Huang, A. Melerzanov, Yanan Du

DOI

2015

Biomaterials as carrier, barrier and reactor for cell-based regenerative medicine

Chunxiao Qi, Xiao-Jun Yan, Chenyu Huang, A. Melerzanov, Yanan Du

Protein & Cell

DOI

2015

Direct intercellular communications dominate the interaction between adipose-derived MSCs and myofibroblasts against cardiac fibrosis

Xiaokang Li, Hui Zhao, Chunxiao Qi, Yang Zeng, Feng Xu, Yanan Du

Protein & Cell

DOI

2015

Preformed gelatin microcryogels as injectable cell carriers for enhanced skin wound healing.

Yang Zeng, Lin Zhu, Q. Han, Wei Liu, Xiaojing Mao, Yaqian Li, Nan-Ze Yu, Siyu Feng, Qinyouen Fu, Xiao-Jun Wang, Yanan Du, R. Zhao

Acta Biomaterialia

DOI

2015

Probing cell–matrix interactions in RGD-decorated macroporous poly (ethylene glycol) hydrogels for 3D chondrocyte culture

Jingjing Zhang, A. Mujeeb, Yanan Du, Jianhao Lin, Z. Ge

Biomedical Materials

DOI

2015

Biomaterial-Assisted Stem Cell Engineering for Tissue Construction and Regeneration

Xiao-Jun Yan, Bing-Jie Wang, Chunxiao Qi, J. Lowrey, Yanan Du

DOI

2015

Abstract 51: Enhanced Wound Healing by Human Adipose-derived Stem Cells and Gelatin Microcryogels in a Nude Mice Model

Lin Zhu, Yang Zeng, Q. Han, Wei Liu, Xiaojing Mao, Yaqian Li, Nan-Ze Yu, Siyu Feng, Qinyouen Fu, Xiaojun Wang, Yanan Du, R. Zhao

DOI

2015

Abstract 51

Lin Zhu, Yang Zeng, Qin You Han, Wei Liu, Xiaojing Mao, Yaqian Li, Nanze Yu, Siyu Feng, Qinyouen Fu, Xiaojun Wang, Yanan Du, Robert Chunhua Zhao

Plastic & Reconstructive Surgery

DOI

2014

Magnetically controllable 3D microtissues based on magnetic microcryogels.

Wei Liu, Yaqian Li, Siyu Feng, Jia Ning, Jingyu Wang, Ma-Ling Gou, Huijun Chen, Feng Xu, Yanan Du

Lab on a Chip

DOI

2014

Micro-scaffold array chip for upgrading cell-based high-throughput drug testing to 3D using benchtop equipment.

Xiaokang Li, Xinyong Zhang, Shan Zhao, Jingyu Wang, Gang Liu, Yanan Du

Lab on a Chip

DOI

2014

Stem Cells: Hepatic Differentiation of Human Embryonic Stem Cells as Microscaled Multilayered Colonies Leading to Enhanced Homogeneity and Maturation (Small 21/2014)

Rui Yao, Jingyu Wang, Xiaokang Li, Da-Jung Jung, Hao Qi, K. Kee, Yanan Du

DOI

2014

Glycerol-mediated nanostructure modification leading to improved transparency of porous polymeric scaffolds for high performance 3D cell imaging.

Shan Zhao, Zhiyuan Shen, Jingyu Wang, Xiaokang Li, Yang Zeng, Bing-Jie Wang, Yong-Hong He, Yanan Du

Biomacromolecules

DOI

2014

Primed 3D injectable microniches enabling low-dosage cell therapy for critical limb ischemia

Yaqian Li, Wei Liu, Fei Liu, Yang Zeng, Simin Zuo, Siyu Feng, Chunxiao Qi, Bing-Jie Wang, Xiao-Jun Yan, A. Khademhosseini, J. Bai, Yanan Du

Proceedings of the National Academy of Sciences of the United States of America

DOI

2014

Engineering cell alignment in vitro.

Yuhui Li, Guoyou Huang, Xiao-Hui Zhang, Lin Wang, Yanan Du, Tian-Jian Lu, Feng Xu

Biotechnology Advances

DOI

2014

Microengineered in vitro model of cardiac fibrosis through modulating myofibroblast mechanotransduction

Hui Zhao, Xiaokang Li, Shan Zhao, Yang Zeng, Long Zhao, H. Ding, Wei Sun, Yanan Du

Biofabrication

DOI

2014

Microcryogels as injectable 3-D cellular microniches for site-directed and augmented cell delivery.

Wei Liu, Yaqian Li, Yang Zeng, Xinyong Zhang, Jingyu Wang, Liping Xie, Xiaokang Li, Yanan Du

Acta Biomaterialia

DOI

2014

Hepatic differentiation of human embryonic stem cells as microscaled multilayered colonies leading to enhanced homogeneity and maturation.

Rui Yao, Jingyu Wang, Xiaokang Li, Da-Jung Jung, Hao Qi, K. Kee, Yanan Du

Small

DOI

2013

Off-the-shelf microsponge arrays for facile and efficient construction of miniaturized 3D cellular microenvironments for versatile cell-based assays.

Shan Zhao, Hui Zhao, Xinyong Zhang, Yaqian Li, Yanan Du

Lab on a Chip

DOI

2013

Recent Advances in Embryonic Stem Cell Engineering Toward Tailored Lineage Differentiation

Zhen Xu, Jingyu Wang, Yanan Du

DOI

2013

A biomimetic physiological model for human adipose tissue by adipocytes and endothelial cell cocultures with spatially controlled distribution

Rui Yao, Yanan Du, Renji Zhang, F. Lin, J. Luan

Biomedical Materials

DOI

2013

Multifaceted applications of nanomaterials in cell engineering and therapy.

Hui Chen, Yang Zeng, W. Liu, Shan Zhao, Jin-Hui Wu, Yanan Du

Biotechnology Advances

DOI

2013

DNA directed self-assembly of shape-controlled hydrogels

Hao Qi, Majid Ghodousi, Yanan Du, Casey N. Grun, Hojae Bae, Peng Yin, A. Khademhosseini

Nature Communications

DOI

2012

1D∼3D Nano‐engineered Biomaterials for Biomedical Applications

Hui Chen, Xiaokang Li, Yanan Du

DOI

2012

Hydrogel as Stem Cell Niche for In Vivo Applications in Regenerative Medicine

Xiaokang Li, C. Wittkowske, Rui Yao, Yanan Du

DOI

2012

Applications in Regenerative Medicine

Xiaokang Li, C. Wittkowske, Rui Yao, Yanan Du

2011

Editorial: nanotechnology for tissue engineering applications

Xiao-Jun Yu, Jun-Ping Wang, Yanan Du, Zu-Wei Ma, Wei He

DOI

2011

Directed assembly of cell-laden microgels for building porous three-dimensional tissue constructs

F. Yanagawa, H. Kaji, Y. Jang, Hojae Bae, Yanan Du, J. Fukuda, Hao Qi, A. Khademhosseini

Journal of Biomedical Materials Research. Part A

DOI

2011

Award Winner in the Young Investigator Category , 2011 Society for Biomaterials Annual Meeting and Exposition , Orlando , Florida , April 13 – 16 , 2011 : Directed assembly of cell-laden microgels for building porous three-dimensional tissue constructs

F. Yanagawa, H. Kaji, Y. Jang, Hojae Bae, Yanan Du, J. Fukuda, Hao Qi, A. Khademhosseini

2011

Sequential assembly of cell-laden hydrogel constructs to engineer vascular-like microchannels

Yanan Du, Majid Ghodousi, Hao Qi, N. Haas, Wenqian Xiao, A. Khademhosseini

Biotechnology and Bioengineering

DOI

2011

Synthesis and characterization of photocrosslinkable gelatin and silk fibroin interpenetrating polymer network hydrogels

Wenqian Xiao, Jian-Kang He, J. Nichol, Lianyong Wang, Ché B Hutson, Ben Wang, Yanan Du, Hong-Song Fan, A. Khademhosseini

Acta Biomaterialia

DOI

2011

Microfluidic Synthesis of Composite Cross-Gradient Materials for Investigating Cell–Biomaterial Interactions

Jian-Kang He, Yanan Du, Yuqi Guo, Matthew J. Hancock, Ben Wang, Hyeongho Shin, Jin-Hui Wu, Di-Chen Li, A. Khademhosseini

Biotechnology and Bioengineering

DOI

2010

A sandwiched microarray platform for benchtop cell-based high throughput screening

Jin-Hui Wu, I. Wheeldon, Yuqi Guo, Ting Lu, Yanan Du, Ben Wang, Jian-Kang He, Yiqiao Hu, A. Khademhosseini

Biomaterials

DOI

2010

Surface-directed assembly of cell-laden microgels

Yanan Du, Majid Ghodousi, Edward Lo, Mahesh K. Vidula, Onur Emiroglu, A. Khademhosseini

Biotechnology and Bioengineering

DOI

2010

Rapid generation of biologically relevant hydrogels containing long-range chemical gradients

Jian-Kang He, Yanan Du, J. L. Villa-Uribe, Changmo Hwang, Di-Chen Li, A. Khademhosseini

Advanced Functional Materials

DOI

2010

Directed assembly of cell-laden hydrogels for engineering functional tissues

N. N. Kachouie, Yanan Du, Hojae Bae, Masoud Khabiry, Amir F. Ahari, B. Zamanian, J. Fukuda, A. Khademhosseini

Organogenesis

DOI

2010

Generating long material gradients by convection and alternating flow in a microchannel

M. Hancock, Yanan Du, Jian-Kang He, J. L. Villa-Uribe, Ben Wang, D. Cropek, A. Khademhosseini

Northeast Bioengineering Conference

DOI

2010

Stem Cells: Patterned Differentiation of Individual Embryoid Bodies in Spatially Organized 3D Hybrid Microgels (Adv. Mater. 46/2010)

Hao Qi, Yanan Du, Lianyong Wang, H. Kaji, Hojae Bae, A. Khademhosseini

DOI

2010

3D HEPATOCYTE MONOLAYER FOR HEPATOCYTE BASED APPLICATIONS

Yanan Du

2010

Patterned Differentiation of Individual Embryoid Bodies in Spatially Organized 3D Hybrid Microgels

Hao Qi, Yanan Du, Lianyong Wang, H. Kaji, Hojae Bae, A. Khademhosseini

Advances in Materials

DOI

2009

Convection driven generation of long-range material gradients

Yanan Du, M. Hancock, Jian-Kang He, J. L. Villa-Uribe, Ben Wang, D. Cropek, A. Khademhosseini

Biomaterials

DOI

2009

Stochastic model of self-assembly of cell-laden hydrogels

Zhenyu Shi, N. Chen, Yanan Du, A. Khademhosseini, M. Alber

Physical review. E, Statistical, nonlinear, and soft matter physics

DOI

2009

A simple microfluidc method for rapid generation of long-range material gradients in microchannels

M. Hancock, Yanan Du, Jinkang He, Jose Uribe-Villa, A. Khademhosseini

2009

Cell Docking in Double Grooves in a Microfluidic Channel

Masoud Khabiry, B. Chung, M. Hancock, H. Soundararajan, Yanan Du, D. Cropek, Won Gu Lee, A. Khademhosseini

Small

DOI

2008

Synthetic sandwich culture of 3D hepatocyte monolayer.

Yanan Du, R. Han, F. Wen, Susanne Ng San San, L. Xia, T. Wohland, H. Leo, Hanry Yu

Biomaterials

DOI

2008

WITHDRAWN: Microfabrication-based engineering of the embryonic and adult stem cell niches.

B. Chung, Yanan Du, Akshay Navaladi, A. Khademhosseini

Biomaterials

DOI

2008

Directed assembly of cell-laden microgels for fabrication of 3D tissue constructs

Yanan Du, Edward Lo, Shamsher Ali, A. Khademhosseini

Proceedings of the National Academy of Sciences of the United States of America

DOI

2008

7 Microfluidic Systems for Engineering Vascularized Tissue Constructs

Yanan Du, D. Cropek, M. Kaazempur-Mofrad, E. Weinberg, A. Khademhosseini, J. Borenstein

2008

Method of Bottom-Up Directed Assembly of Cell-Laden Microgels

Yanan Du, Edward Lo, Mahesh K. Vidula, Masoud Khabiry, A. Khademhosseini

Cellular and Molecular Bioengineering

DOI

2007

Identification and characterization of a novel prespheroid 3-dimensional hepatocyte monolayer on galactosylated substratum.

Yanan Du, R. Han, S. Ng, Jun Ni, Wanxin Sun, T. Wohland, S. Ong, L. Kuleshova, Hanry Yu

Tissue engineering

DOI

2006

3D hepatocyte monolayer on hybrid RGD/galactose substratum.

Yanan Du, S. Chia, R. Han, Shi Chang, Hui-Huan Tang, Hanry Yu

Biomaterials

DOI

Self-assembly of gelatin microcarrier-based MSC microtissues for spinal cord injury repair

Hai-Feng Liu, Xiaojun Yan, Jingwei Jiu, Jiao-Jiao Li, Yuanyuan Zhang, Guishan Wang, Di-Jun Li, Lei Yan, Yanan Du, Bin Zhao, Bin Wang

Chemical Engineering Journal

DOI

精选作品

期刊论文

Bone marrow-inspired DLL1-presenting microparticles enhance asymmetric division and maintenance of mouse hematopoietic stem and progenitor cells

Multi-lineage hepatic organoids reveal toxic exosome mediated indirect hepatotoxicity

Viscoelastic hydrogel primed CAR-macrophage for pulmonary fibrosis treatment

Porous microscaffold enables spontaneous hematopoietic cell differentiation and continuous macrophage production from hPSCs for therapy.

Corrigendum to "TGase-mediated cell membrane modification and targeted cell delivery to inflammatory endothelium" [Biomaterials, Volume 269, February 2021, 120276].

Tension-induced directional migration of hepatic stellate cells potentially coordinates liver fibrosis progression

Author Correction: Expansion of human megakaryocyte-biased hematopoietic stem cells by biomimetic Microniche

Correction: Consistent apparent Young’s modulus of human embryonic stem cells and derived cell types stabilized by substrate stiffness regulation promotes lineage specificity maintenance

Centimeter‐Scale Self‐Assembling Tendon Organoids Drive Tissue Regeneration

Hydrogel Microparticle Encapsulation Enhances In Vivo Peptide Delivery of Recombinant Probiotics

Correction: Image-based evaluation of single-cell mechanics using deep learning

Image-based evaluation of single-cell mechanics using deep learning

hESCs‐derived Organoids Achieve Liver Zonation Features through LSEC Modulation

Growing meat on autoclaved vegetables with biomimetic stiffness and micro-patterns

Fiber recruitment drives a phase transition of cell polarization at a critical cell spacing in matrix-mediated tissue remodeling

Corrigendum to “Modulating immune responses for enhanced cell therapies: the dual role of multi-scale biomaterials” [EngMedicine 1 (2024) 100038]

Artificial cells with liquid–liquid phase separation–regulated cell-free protein synthesis

Chemo-mechanotherapy of fibrosis: dynamic control of biological materials through tissue-architecture-dependent crosslink disruption

Corrigendum to ‘Pathology-targeted cell delivery via injectable micro-scaffold capsule mediated by endogenous TGase’ [Biomaterials, 126 (2017), 17950]

Gelatin sponge patch grafting of microcryogel-based three-dimensional mesenchymal stem cells to alleviate acute liver failure

Correction: Magnetically controllable 3D microtissues based on magnetic microcryogels

Hepatic hypertension on-a-chip identifies GPR116 as a hydrostatic pressure mechanosensor to regulate vascular injury in cirrhosis

Cortical Actin Depolymerisation in 3D Cell Culture Enhances Extracellular Vesicle Secretion and Therapeutic Effects

Correction to “Sequential Assembly of Cell‐Laden Hydrogel Constructs to Engineer Vascular‐Like Microchannels”

3D Mechanical Response Stem Cell Complex Repairs Spinal Cord Injury by Promoting Neurogenesis and Regulating Tissue Homeostasis

MICROFLUIDIC-PREPARATION OF VISCOELATIC MICROFIBER FOR ENHANCED FABRICATION OF ARTIFICIAL MEAT

Viscoelasticity of ECM and cells—origin, measurement and correlation

Modulating immune responses for enhanced cell therapies: The dual role of multi-scale biomaterials

Superimposed Electric Field Enhanced Electrospray for High‐Throughput and Consistent Cell Encapsulation

Water Transport‐Induced Liquid–Liquid Phase Separation Facilitates Gelation for Controllable and Facile Fabrication of Physically Crosslinked Microgels

Exosomes derived from 3D-cultured MSCs alleviate knee osteoarthritis by promoting M2 macrophage polarization through miR-365a-5p and inhibiting TLR2/Myd88/NF-κB pathway

Tissue-engineered mesenchymal stem cell constructs alleviate tendinopathy by suppressing vascularization

Advanced glycation end-products as mediators of the aberrant crosslinking of extracellular matrix in scarred liver tissue

Gelatin-based 3D biomimetic scaffolds platform potentiates culture of cancer stem cells in esophageal squamous cell carcinoma.

Biophysical cues of bone marrow-inspired scaffolds regulate hematopoiesis of hematopoietic stem and progenitor cells.

Response to a Comment on “Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis”

Enhanced bone regeneration via endochondral ossification using Exendin-4-modified mesenchymal stem cells

Cell mediated ECM-degradation as an emerging tool for anti-fibrotic strategy

Transglutaminase-crosslinked extracellular matrix in cirrhotic liver tissues provides pro-fibrotic mechano-microenvironment for cells

In situ self-assembled organoid for osteochondral tissue regeneration with dual functional units.

Expansion of human megakaryocyte-biased hematopoietic stem cells by biomimetic Microniche

Large-Scale Cell Production Based on GMP-Grade Dissolvable Porous Microcarriers.

Engineered meatballs via scalable skeletal muscle cell expansion and modular micro-tissue assembly using porous gelatin micro-carriers.

Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis

Precise cell therapy for liver fibrosis: Endothelial cell and macrophage therapy

Injectable bone marrow microniches by co-culture of HSPCs with MSCs in 3D microscaffolds promote hematopoietic reconstitution from acute lethal radiation

3D biomaterial P scaffolds carrying umbilical cord mesenchymal stem cells improve biointegration of keratoprosthesis

Mesenchymal Stem Cells (MSCs): A Novel Therapy for Type 2 Diabetes

GMP‐grade microcarrier and automated closed industrial scale cell production platform for culture of MSCs

A Novel Step-T-Junction Microchannel for the Cell Encapsulation in Monodisperse Alginate-Gelatin Microspheres of Varying Mechanical Properties at High Throughput

Research progress of stem cell therapy for endometrial injury

Generation of monodisperse micro-droplets within the stable narrowing jetting regime: effects of viscosity and interfacial tension

Targeted cell therapy for partial-thickness cartilage defects using membrane modified mesenchymal stem cells by transglutaminase 2.

Cell engineering techniques improve pharmacology of cellular therapeutics

Efficient endothelial and smooth muscle cell differentiation from human pluripotent stem cells through a simplified insulin-free culture system.

Mechanical communication in fibrosis progression.

Key considerations on the development of biodegradable biomaterials for clinical translation of medical devices: With cartilage repair products as an example

Collagen crosslinking: effect on structure, mechanics and fibrosis progression

Asporin inhibits collagen matrix‐mediated intercellular mechanocommunications between fibroblasts during keloid progression

A low dose cell therapy system for treating osteoarthritis: In vivo study and in vitro mechanistic investigations

Synthetic liver fibrotic niche extracts achieve in vitro hepatoblasts phenotype enhancement and expansion

Exendin-4 gene modification and microscaffold encapsulation promote self-persistence and antidiabetic activity of MSCs

Large-Scale Expansion of Umbilical Cord Mesenchymal Stem Cells with Microcarrier Tablets in Bioreactor.

TGase-mediated cell membrane modification and targeted cell delivery to inflammatory endothelium.

Dispersible and Dissolvable Porous Microcarrier Tablets Enable Efficient Large-Scale Human Mesenchymal Stem Cell Expansion

Functional Nanoparticles Activate a Decellularized Liver Scaffold for Blood Detoxification.

Enhanced single-cell encapsulation in microfluidic devices: From droplet generation to single-cell analysis.

Engineering 3D functional tissue constructs using self-assembling cell-laden microniches.

Construction of Microunits by Adipose-Derived Mesenchymal Stem Cells Laden with Porous Microcryogels for Repairing an Acute Achilles Tendon Rupture in a Rat Model

Matrix-transmitted paratensile signaling enables myofibroblast–fibroblast cross talk in fibrosis expansion

Consistent apparent Young’s modulus of human embryonic stem cells and derived cell types stabilized by substrate stiffness regulation promotes lineage specificity maintenance

TGase‐Enhanced Microtissue Assembly in 3D‐Printed‐Template‐Scaffold (3D‐MAPS) for Large Tissue Defect Reparation

Comparison of Chondrocytes in Knee Osteoarthritis and Regulation by Scaffold Pore Size and Stiffness

Bottom‐up Tissue Engineering: TGase‐Enhanced Microtissue Assembly in 3D‐Printed‐Template‐Scaffold (3D‐MAPS) for Large Tissue Defect Reparation (Adv. Healthcare Mater. 18/2020)

Intra-articular Injection of Cell-laden 3D Microcryogels Empower Low-dose Cell Therapy for Osteoarthritis in a Rat Model

High throughput scaffold-based 3D micro-tumor array for efficient drug screening and chemosensitivity testing.

Injectable nanohydroxyapatite-chitosan-gelatin microscaffolds induce regeneration of knee subchondral bone cyst-like lesions

Evaluation of intervertebral disc regeneration with injection of mesenchymal stem cells encapsulated in PEGDA-microcryogel delivery system using quantitative T2 mapping: a study in canines.