百晓学者学者目录

张英

讲师，洛阳师范学院

精选作品

期刊论文

2024

Functional mouse hepatocytes derived from interspecies chimeric livers effectively mitigate chronic liver fibrosis

Cheng Huang, Haiping Jiang, J. Dong, Liyuan Jiang, Jie Li, Jing Xu, T. Cui, Le-Yun Wang, Xin Li, Gui-Hai Feng, Ying Zhang, Tian-Da Li, Wei Li, Qi Zhou

Stem Cell Reports

DOI

2024

Knockout and Replacement Gene Surgery to Treat Rhodopsin-Mediated Autosomal Dominant Retinitis Pigmentosa

Xuehan Sun, Chen Liang, Yang-Can Chen, T. Cui, Jiabao Han, Moyu Dai, Ying Zhang, Qi Zhou, Wei Li

Human Gene Therapy

DOI

2023

Deciphering the placental abnormalities associated with somatic cell nuclear transfer at single-nucleus resolution

Liyuan Jiang, Xin Wang, Le-Yun Wang, Si-Nan Ma, Ya-Li Ding, Chao Liu, Si-Qi Wang, Xuan Shao, Ying Zhang, Zhi-Kun Li, Wei Li, Gui-Hai Feng, Qi Zhou

Protein & Cell

DOI

2023

An optimized prime editing system for efficient modification of the pig genome

Yanan Qi, Ying Zhang, Shuangjie Tian, Ruo-Jun Zong, Xinghui Yan, Yu Wang, Yan-Fang Wang, Jian-Guo Zhao

Science China Life Sciences

DOI

2023

Nanos3 knockout pigs to model transplantation and reconstruction of the germline

Jing Wang, Jilong Ren, Qingwei Wang, Chongyang Li, Zhiqiang Han, Tian-Zhi Chen, Ke Sun, Gui-Hai Feng, Ying Zhang, Jianyong Han, Qi Zhou, W. Li, Da-Wei Yu, Tang Hai

Cell Proliferation

DOI

2023

Live‐cell imaging reveals redox metabolic reprogramming during zygotic genome activation

Hao Sun, Zhuo Zhang, Tianda Li, Ting Li, Wei-Cai Chen, Tian-Shi Pan, Sen Fang, Chao Liu, Ying Zhang, Le-Yun Wang, Gui-Hai Feng, Wei Li, Qi Zhou, Yu-Zheng Zhao

Journal of Cellular Physiology

DOI

2022

Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons

Zhengqiang He, Yu-Huan Li, Gui-Hai Feng, Xuewei Yuan, Zongbao Lu, Min Dai, Yanping Hu, Ying Zhang, Qi Zhou, Wei Li

Advancement of science

DOI

2022

Influence of feeder cells on transcriptomic analysis of pluripotent stem cells

Hai-Feng Wan, Rui Fu, Man Tong, Yukai Wang, Libin Wang, Siqi Wang, Ying Zhang, Wei Li, Xiu-Jie Wang, Gui-Hai Feng

Cell Proliferation

DOI

2022

Rational engineering of adeno‐associated virus capsid enhances human hepatocyte tropism and reduces immunogenicity

Jiabao Han, Li-Yu Zhu, Jing-Wen Zhang, Lu Guo, Xuehan Sun, Cheng Huang, Kai Xu, Ying Zhang, Wei Li, Qi Zhou

Cell Proliferation

DOI

2022

SPATA33 affects the formation of cell adhesion complex by interacting with CTNNA3 in TM4 cells

Ying Zhang

Cell and Tissue Research

DOI

2021

Continuous expression of reprogramming factors induces and maintains mouse pluripotency without specific growth factors and signaling inhibitors

Yi-Huan Mao, Libin Wang, Bei Zhong, Ning Yang, Zhi-Kun Li, T. Cui, Gui-Hai Feng, Wei Li, Ying Zhang, Qi Zhou

Cell Proliferation

DOI

2021

Transcriptome and DNA Methylation Profiles of Mouse Fetus and Placenta Generated by Round Spermatid Injection

Haibo Zhu, Hao Sun, Da-Wei Yu, Tian-Da Li, Hai Tang, Chao Liu, Ying Zhang, Yurong Chen, Xiangpeng Dai, Zi-Yi Li, Wei Li, Rui-Zhi Liu, Gui-Hai Feng, Qi Zhou

Frontiers in Cell and Developmental Biology

DOI

2021

Enhancing targeted transgene knock‐in by donor recruitment

Guanyi Jiao, Chen-Xin Wang, Yang-Can Chen, Moyu Dai, Ying Zhang, Wei Li

Cell Proliferation

DOI

2020

Correction: Generation of qualified clinical-grade functional hepatocytes from human embryonic stem cells in chemically defined conditions

Zhongwen Li, Jun Wu, Lei Wang, Weifang Han, Juan Yu, Xin Liu, Yukai Wang, Ying Zhang, Gui-Hai Feng, Wei Li, G. Stacey, Qi Gu, Baoyang Hu, Liu Wang, Qi Zhou, Jie Hao

Cell Death and Disease

DOI

2020

Treating Bietti crystalline dystrophy in a high-fat diet-exacerbated murine model using gene therapy

Bin Qu, Shijing Wu, Guanyi Jiao, X. Zou, Zhi-Kun Li, Lu Guo, Xuehan Sun, Cheng Huang, Zi-Xi Sun, Ying Zhang, Hui Li, Qi Zhou, R. Sui, Wei Li

Gene Therapy

DOI

2020

IL2RG‐deficient minipigs generated via CRISPR/Cas9 technology support the growth of human melanoma‐derived tumours

Jilong Ren, Da-Wei Yu, Rui Fu, Peipei An, Ren-Ren Sun, Zhengzhu Wang, Runfa Guo, Haoyun Li, Ying Zhang, Zi-Yi Li, Yong-Guang Yang, Wei Li, Hai Tang, Zheng Hu

Cell Proliferation

DOI

2020

Cooperation-based sperm clusters mediate sperm oviduct entry and fertilization

Yongcun Qu, Qi Chen, Shanshan Guo, Chiyuan Ma, Yonggang Lu, Junchao Shi, Shichao Liu, Tong Zhou, Taichi Noda, Jingjing Qian, Liwen Zhang, Xi-Li Zhu, Xiaohua Lei, Yu-Jing Cao, Wei Li, N. Plachta, M. Matzuk, M. Ikawa, E. Duan, Ying Zhang, Hongmei Wang

Protein & Cell

DOI

2020

SPATA33 is an autophagy mediator for cargo selectivity in germline mitophagy

Ying Zhang, Xu Xu, Mengxin Hu, Xin Wang, Hanhua Cheng, Rongjia Zhou

Cell Death and Differentiation

DOI

2019

利用单倍体干细胞印记修饰产生孤雌和孤雄小鼠

李治琨，王乐韵，王立宾，冯桂海，袁雪薇，Chao Liu，Kai Xu，Yu-Huan Li，Hai-Feng Wan，Ying Zhang，Yu-Fei Li，Xin Li，李伟，周琪，胡宝洋

《科学新闻》

2019

The expanding repertoire of hereditary information carriers

Ying Zhang, Qi Chen

Development

DOI

2019

An exonic splicing enhancer mutation in DUOX2 causes aberrant alternative splicing and severe congenital hypothyroidism in Bama pigs

Chunwei Cao, Ying Zhang, Qitao Jia, Xiao Wang, Qiantao Zheng, Hong-Yong Zhang, R. Song, Yongshun Li, Ai-Ling Luo, Qianlong Hong, Guosong Qin, Jing Yao, Nan Zhang, Yan-Fang Wang, Hongmei Wang, Qi Zhou, Jianguo Zhao

Disease Models & Mechanisms

DOI

2019

Domesticated cynomolgus monkey embryonic stem cells allow the generation of neonatal interspecies chimeric pigs

Rui Fu, Da-Wei Yu, Jilong Ren, Chongyang Li, Jing Wang, Gui-Hai Feng, Xuepeng Wang, Hai-Feng Wan, Tian-Da Li, Libin Wang, Ying Zhang, Hai Tang, Wei Li, Qi Zhou

Protein & Cell

DOI

2019

A harlequin ichthyosis pig model with a novel ABCA12 mutation can be rescued by acitretin treatment

Xiao Wang, Chunwei Cao, Yongshun Li, Hai Tang, Qitao Jia, Ying Zhang, Qiantao Zheng, Jing Yao, Guosong Qin, Hong-Yong Zhang, R. Song, Yan-Fang Wang, Guang-Hou Shui, S. Lam, Zhong-Hua Liu, Hong Wei, Anming Meng, Qi Zhou, Jianguo Zhao

Journal of Molecular Cell Biology

DOI

2019

Generation of qualified clinical-grade functional hepatocytes from human embryonic stem cells in chemically defined conditions

Zhongwen Li, Jun Wu, Lei Wang, Weifang Han, Juan Yu, Xin Liu, Yukai Wang, Ying Zhang, Gui-Hai Feng, Wei Li, G. Stacey, Qi Gu, Baoyang Hu, Liu Wang, Qi Zhou, Jie Hao

Cell Death and Disease

DOI

2019

Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells.

Xiu-Ying Zhong, Peng Cui, Yong-Ping Cai, Li-Hua Wang, Xiao-Ping He, Peipei Long, Kang-Yang Lu, Ronghui Yan, Ying Zhang, Xin Pan, Xiao-Yang Zhao, Wei Li, Hua-Feng Zhang, Qi Zhou, P. Gao

Cell Metabolism

DOI

2019

Reprogramming of fibroblasts to uterine glandular epithelium by a chemical cocktail induction

Xuewei Yuan, Zhengquan He, Junjie Mao, Yanping Hu, Xin Liu, Jia Guo, Zhong-Hua Liu, Ying Zhang, Wei Li, Qi Zhou

Cell Discovery

DOI

2019

Rbm14 maintains the integrity of genomic DNA during early mouse embryogenesis via mediating alternative splicing

Jing Li, Chen-Xin Wang, Gui-Hai Feng, Linlin Zhang, Guilai Chen, Hao Sun, Jia-Qiang Wang, Ying Zhang, Qi Zhou, Wei Li

Cell Proliferation

DOI

2019

A novel porcine model reproduces human oculocutaneous albinism type II

Ying Zhang, Qianlong Hong, Chunwei Cao, Li-Zhu Yang, Yongshun Li, Hai Tang, Hong-Yong Zhang, Qi Zhou, R. Sui, Jianguo Zhao

Cell Discovery

DOI

2019

The effect of clinical-grade retinal pigment epithelium derived from human embryonic stem cells using different transplantation strategies

Lei Wang, Wei Wu, Qi Gu, Zengping Liu, Qiyou Li, Zhongwen Li, Jinhui Fang, Wen-Jing Liu, Jun Wu, Ying Zhang, Liu Wang, Haiwei Xu, Wei Li, Baoyang Hu, Qi Zhou, Zheng-Qin Yin, Jie Hao

Protein & Cell

DOI

2018

Individual blastomeres of 4- and 8-cell embryos have ability to develop into a full organism in mouse.

Xinxin Zhang, Tianda Li, Linlin Zhang, Liyuan Jiang, T. Cui, Xuewei Yuan, Chen-Xin Wang, Zhong-Hua Liu, Ying Zhang, Wei Li, Qi Zhou

Journal of genetics and genomics = Yi chuan xue bao

DOI

2018

Caffeine consumption during early pregnancy impairs oviductal embryo transport, embryonic development and uterine receptivity in mice†

Jingjing Qian, Yun-Fang Zhang, Yongcun Qu, Liwen Zhang, Junchao Shi, Xudong Zhang, Shichao Liu, B. Kim, S. Hwang, Tong Zhou, Qi Chen, S. M. Ward, E. Duan, Ying Zhang

Biology of Reproduction

DOI

2018

Generation of Bimaternal and Bipaternal Mice from Hypomethylated Haploid ESCs with Imprinting Region Deletions.

Zhi-Kun Li, Le-Yun Wang, Libin Wang, Gui-Hai Feng, Xuewei Yuan, Chao Liu, Kai Xu, Yu-Huan Li, Hai-Feng Wan, Ying Zhang, Yufei Li, Xin Li, Wei Li, Qi Zhou, Baoyang Hu

Cell Stem Cell

DOI

2018

Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs

Yun-Fang Zhang, Xudong Zhang, Junchao Shi, F. Tuorto, Xin Li, Yusheng Liu, Reinhard Liebers, Liwen Zhang, Yongcun Qu, Jingjing Qian, Maya Pahima, Ying Liu, Menghong Yan, Zhong-Hong Cao, Xiaohua Lei, Yu-Jing Cao, Hongying Peng, Shichao Liu, Yue Wang, Huili Zheng, Rebekah J. Woolsey, D. Quilici, Q. Zhai, Lei Li, Tong Zhou, Wei Yan, F. Lyko, Ying Zhang, Qi Zhou, E. Duan, Qi Chen

Nature Cell Biology

DOI

2018

A fully defined static suspension culture system for large-scale human embryonic stem cell production

Xia Li, Ruoyu Ma, Qi Gu, Lingmin Liang, Lei Wang, Ying Zhang, Xian-Ning Wang, Xin Liu, Zhongwen Li, Jinhui Fang, Jun Wu, Yukai Wang, Wei Li, Baoyang Hu, Liu Wang, Qi Zhou, Jie Hao

Cell Death and Disease

DOI

2018

Generation of clinical‐grade functional cardiomyocytes from human embryonic stem cells in chemically defined conditions

Yuanqing Tan, Peng-Cheng Han, Qi Gu, Gang Chen, Lei Wang, Ruoyu Ma, Jun Wu, Chunjing Feng, Ying Zhang, Liu Wang, Baoyang Hu, Wei Li, Jie Hao, Qi Zhou

Journal of Tissue Engineering and Regenerative Medicine

DOI

2018

MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation

Wei Zhang, Gui-Hai Feng, Libin Wang, Fei Teng, Liu Wang, Wei Li, Ying Zhang, Qi Zhou

Journal of Molecular Cell Biology

DOI

2018

Rescuing ocular development in an anophthalmic pig by blastocyst complementation

Hong-Yong Zhang, Jiao-Jiao Huang, Zechen Li, Guosong Qin, Nan Zhang, Hai Tang, Qianlong Hong, Qiantao Zheng, Ying Zhang, R. Song, Jing Yao, Chunwei Cao, Jianguo Zhao, Qi Zhou

EMBO Molecular Medicine

DOI

2018

RBM14 is indispensable for pluripotency maintenance and mesoderm development of mouse embryonic stem cells.

Guilai Chen, Da Zhang, Linlin Zhang, Gui-Hai Feng, Boya Zhang, Yi-Hui Wu, Wei Li, Ying Zhang, Baoyang Hu

Biochemical and Biophysical Research Communications - BBRC

DOI

2017

A single-cell snapshot of cell-fate decisions

Ying Zhang, Qi Zhou

Journal of Biological Chemistry

DOI

2017

Thyroid hormone regulates hematopoiesis via the TR-KLF9 axis.

Ying Zhang, Yu-Feng Xue, Chunwei Cao, Jiao-Jiao Huang, Qianlong Hong, Hai Tang, Qitao Jia, Xian-Long Wang, Guosong Qin, Jing Yao, Xiao Wang, Qiantao Zheng, Rui Zhang, Yongshun Li, Ai-Ling Luo, N. Zhang, G. Shi, Yan-Fang Wang, H. Ying, Zhong-Hua Liu, Hongmei Wang, Anming Meng, Qi Zhou, Hong Wei, Feng Liu, Jianguo Zhao

Blood

DOI

2017

Generation of Mouse Haploid Somatic Cells by Small Molecules for Genome-wide Genetic Screening.

Zhengquan He, Baolong Xia, Yukai Wang, Jing Li, Gui-Hai Feng, Linlin Zhang, Yu-Huan Li, Hai-Feng Wan, Tian-Da Li, Kai Xu, Xuewei Yuan, Yufei Li, Xinxin Zhang, Ying Zhang, Liu Wang, Wei Li, Qi Zhou

Cell Reports

DOI

2017

Mitochondrially produced ATP affects stem cell pluripotency via Actl6a‐mediated histone acetylation

Ying Zhang, Peng Cui, Yu-Huan Li, Gui-Hai Feng, Man Tong, Lu Guo, Tianda Li, Lei Liu, Wei Li, Qi Zhou

The FASEB Journal

DOI

2017

Pilot study of large-scale production of mutant pigs by ENU mutagenesis

Tang Hai, Chunwei Cao, Hai-Tao Shang, Wei-Wei Guo, Y. Mu, Shu-Lin Yang, Ying Zhang, Qiantao Zheng, Zhang Tao, Xian-Long Wang, Yu Liu, Qing-Ran Kong, Kui Li, Dayu Wang, Meng Qi, Qianlong Hong, Rui Zhang, Xiupeng Wang, Qitao Jia, Xiao Wang, Guosong Qin, Yongshun Li, Ai-Ling Luo, Weiwu Jin, Jing Yao, Jiao-Jiao Huang, Hong-Yong Zhang, Menghua Li, Xiangmo Xie, Xuejuan Zheng, Kenan Guo, Qinghua Wang, Shibin Zhang, Liang Li, Fei Xie, Yu Zhang, X. Weng, Z. Yin, K. Hu, Yi-Mei Cong, Peng Zheng, H. Zou, Leilei Xin, Ji-han Xia, Jinxue Ruan, He-Gang Li, Wei-Min Zhao, Jing Yuan, Zizhan Liu, Weiwang Gu, Ming Li, Yong Wang, Hongmei Wang, Shi-Ming Yang, Zhong-Hua Liu, Hong Wei, Jianguo Zhao, Qi Zhou, Anming Meng

eLife

DOI

2017

Creation of miniature pig model of human Waardenburg syndrome type 2A by ENU mutagenesis

Tang Hai, Wei-Wei Guo, Jing Yao, Chunwei Cao, Ai-Ling Luo, Meng Qi, Xian-Long Wang, Xiao Wang, Jiao-Jiao Huang, Ying Zhang, Hong-Yong Zhang, Dayu Wang, Hai-Tao Shang, Qianlong Hong, Rui Zhang, Qitao Jia, Qiantao Zheng, Guosong Qin, Yongshun Li, Zhang Tao, Weiwu Jin, Zheng-Yi Chen, Hongmei Wang, Qi Zhou, Anming Meng, Hong Wei, Shi-Ming Yang, Jianguo Zhao

Human Genetics

DOI

2016

Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder

Qi Chen, Menghong Yan, Zhong-Hong Cao, Xin Li, Yun-Fang Zhang, Junchao Shi, Gui-Hai Feng, Hongying Peng, Xudong Zhang, Ying Zhang, Jingjing Qian, E. Duan, Q. Zhai, Qi Zhou

Science

DOI

2016

Ubiquitously expressed genes participate in cell‐specific functions via alternative promoter usage

Gui-Hai Feng, Man Tong, Baolong Xia, Guan-Zheng Luo, M. Wang, Dong-fang Xie, Hai-Feng Wan, Ying Zhang, Qi Zhou, Xiu-Jie Wang

EMBO Reports

DOI

2016

A non-invasive method to determine the pluripotent status of stem cells by culture medium microRNA expression detection

Ying Zhang, Gui-Hai Feng, Kai Xu, Libin Wang, Peng Cui, Yu-Huan Li, Chen-Xin Wang, Fei Teng, Jie Hao, Hai-Feng Wan, Yuanqing Tan, Xiu-Jie Wang, Qi Zhou

Scientific Reports

DOI

2015

Dynamic transcriptional symmetry-breaking in pre-implantation mammalian embryo development revealed by single-cell RNA-seq

Junchao Shi, Qi Chen, Xin Li, Xiu-Deng Zheng, Ying Zhang, J. Qiao, Fu-Chou Tang, Yi Tao, Qi Zhou, E. Duan

Development

DOI

2015

m(6)A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency.

Tong Chen, Ya-Juan Hao, Ying Zhang, Miao-Miao Li, Meng Wang, Weifang Han, Yong-Sheng Wu, Ying Lv, Jie Hao, Libin Wang, Ang Li, Ying Yang, Kang-Xuan Jin, Xu Zhao, Yu-Huan Li, X. Ping, Weiyi Lai, Ligang Wu, Gui-Bin Jiang, Hailin Wang, Lisi Sang, Xiu-Jie Wang, Yun-Gui Yang, Qi Zhou

Cell Stem Cell

DOI

2015

巴马小型猪 OCA 2基因序列、组织表达分析及载体构建研究

Qianlong Hong, Ying Zhang, Chunwei Cao, Xian-Long Wang, Jian-Guo Zhao

DOI

2015

Method for mirna to regulate modification level of m6a and applications thereof

Qi Zhou, Yun-Gui Yang, Xiu-Jie Wang, Tong Chen, Ying Zhang, Ya-Juan Hao, Miao-Miao Li, Meng Wang

2015

Correctionm6A RNA Methylation Is Regulated by MicroRNAs and Promotes Reprogramming to Pluripotency

Tong Chen, Ya-Juan Hao, Ying Zhang, Miao-Miao Li, Meng Wang, W. Han, Yong-Sheng Wu, Ying Lv, Jie Hao, Libin Wang, Ang Li, Ying-Chao Yang, Kang-Xuan Jin, Xu Zhao, Yu-Huan Li, X. Ping, Wei-Yi Lai, Ligang Wu, Qi Zhou

DOI

2013

MicroRNA-323-3p Regulates the Activity of Polycomb Repressive Complex 2 (PRC2) via Targeting the mRNA of Embryonic Ectoderm Development (Eed) Gene in Mouse Embryonic Stem Cells*

Ying Zhang, Fei Teng, Guan-Zheng Luo, Meng Wang, Man Tong, Xiao-Yang Zhao, Liu Wang, Xiu-Jie Wang, Qi Zhou

Journal of Biological Chemistry

DOI

2013

Identification of a small molecule 1,4-bis-[4-(3-phenoxy-propoxy)-but-2-ynyl]-piperazine as a novel inhibitor of the transcription factor p53

Xin Liu, Ying Zhang, Man Tong, Xiuying Liu, Guan-Zheng Luo, Dong-fang Xie, Shao-fang Ren, Dong-hui Bai, Liu Wang, Qi Zhou, Xiu-Jie Wang

Acta Pharmacologica Sinica

DOI

2011

iPS cells generated without c-Myc have active Dlk1-Dio3 region and are capable of producing full-term mice through tetraploid complementation

Wei Li, Xiao-Yang Zhao, Hai-Feng Wan, Ying Zhang, Lei Liu, Zhuo Lv, Xiu-Jie Wang, Liu Wang, Qi Zhou

Cell Research

DOI

会议论文

2018

Insights into autophagosome biogenesis during oogenesis

Jia Yuan, Yue Sheng, Ying Song, Ying Zhang, Hanhua Cheng, Rongjia Zhou

《2018中国遗传学会第十次全国会员代表大会暨学术讨论会论文摘要汇编》

DOI

研究方向

动物生殖基因功能研究

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