李聪｜复旦大学｜学者主页

2026

AI-Assisted SERS Decoding of Dual Enzymatic Activity for Intraoperative Chemical Mapping of Epilepsy

Jing Zhao, Zhihang Chen, Zihao Wei, Ming Chen, Yuncan Chen, Xinge Liang, Caixia Liu, Renxiao Wang, Xiang Zou, Jinhua Yu, Yifei Qi, Cong Wang, Cong Li

Journal of the American Chemical Society

DOI

2026

Cascade‐Amplified Ratiometric Fluorescent Probe for Time‐Locked Imaging Epilepsy

Xin Wang, Bohan Li, Min Li, Yuncan Chen, Yurui Tang, Aiyan Ji, Jing Zhao, Chenchen Sun, Zhenrong Li, Dan Ni, Yanlong Cheng, Wanbing Sun, Zuhai Lei, Jing Wang, Annamaria Vezzani, Xiaoyu Li, Cong Li, Xiao Zhu, Zhen Cheng, Cong Wang

Advanced Materials

DOI

2026

Adenosine 2A receptor drives microglial efferocytosis to accelerate white matter repair and functional recovery after stroke

Yan Deng, Qian He, Bolin Yao, Xiang Chen, Guangli Cheng, Minhua Xu, Jiachun Hu, Luís Graça, Xiao Zhu, Xiao‐Yong Zhang, Yan You, Cong Li

Science Signaling

DOI

2025

An AI-assisted fluorescence microscopic system for screening mitophagy inducers by simultaneous analysis of mitophagic intermediates

Yicheng Wang, Pengfei Song, Heqing Zhou, Pengwei Wang, Yan Li, Zhiyong Shao, Lu Wang, Yan You, Zuhai Lei, Jinhua Yu, Cong Li

Nature Communications

DOI

2025

Outside Back Cover: Tandem Dual‐Ratiometric SERS Probe Enables Raman Imaging of Neurological pH Fluctuations in Epilepsy (Angew. Chem. 25/2025)

Jian Zhao, Yuncan Chen, Yurui Tang, Bohan Li, Qinyue Wang, Junfeng Wang, Xihui Gao, Yunle Zhang, Jing Wang, Zuhai Lei, Cong Li, Cong Wang

Angewandte Chemie

DOI

2025

Outside Back Cover: Tandem Dual‐Ratiometric SERS Probe Enables Raman Imaging of Neurological pH Fluctuations in Epilepsy (Angew. Chem. Int. Ed. 25/2025)

Jian Zhao, Yuncan Chen, Yurui Tang, Bohan Li, Qinyue Wang, Junfeng Wang, Junfeng Wang, Xihui Gao, Yunle Zhang, Jing Wang, Jing Wang, Zuhai Lei, Cong Li, Cong Wang

Angewandte Chemie International Edition

DOI

2025

Tandem Dual‐Ratiometric SERS Probe Enables Raman Imaging of Neurological pH Fluctuations in Epilepsy

Jian Zhao, Yuncan Chen, Yurui Tang, Bohan Li, Qinyue Wang, Junfeng Wang, Xihui Gao, Yunle Zhang, Jing Wang, Zuhai Lei, Cong Li, Cong Wang

Angewandte Chemie

DOI

2025

Edaravone-Encapsulated Agonistic Micelles Rescue Ischemic Brain Tissue by Tuning Blood-Brain Barrier Permeability: Erratum

Qu Jin, Yu Chen Cai, Sihan Li, Haoran Liu, Xingyu Zhou, Chun‐Qiang Lu, Xihui Gao, Jun Qian, Jun Zhang, Shenghong Ju, Cong Li

Theranostics

DOI

2025

Tailoring imaging probes for defining glioma invasive margins: Tracing the molecular footprints of cancer cells

He Qian, Minghao Yang, Pengwei Wang, Luís Graça, Hongzan Sun, Cong Li

Biomaterials

DOI

2025

Adoptive macrophages suppress glioblastoma growth by reversing immunosuppressive microenvironment through programmed phenotype repolarization

Yang Fan, Hang Yin, Jing Zhao, Bolin Yao, Guangli Cheng, Yaqi Yang, Minghao Yang, Luo Chen, Jian Chen, Ji Zhou, Li Ren, Botao Zhao, Xiao‐Yong Zhang, Cong Wang, Xihui Gao, Cong Li

Cell Reports

DOI

2025

CRISPR/Cas9-Engineered Triple-Fusion Reporter Gene Imaging System for Monitoring Transplanted Neural Progenitor Cells in Ischemic Stroke

Xiaoyi Li, Yan Zhong, Chentao Jin, Xiang Chen, Xingyue Cui, Yangyang Xu, Yang Fan, Fahuan Song, Peili Cen, La Dong, Kaiwu Yu, Qinggang He, Jing Wang, Shijun Hu, Xiao‐Yong Zhang, Cong Li, Mei Tian, Hong Zhang

Radiology

DOI

2025

Ultrabright ratiometric Raman-guided epilepsy surgery by intraoperatively visualizing proinflammatory microglia

Cong Wang, Zhi Li, Xiao Zhu, Wanbing Sun, Yue Ding, Wenjia Duan, Difei Wang, Yiqing Jiang, Ming Chen, Yuncan Chen, Jiayi Hu, Zheping Cai, Jing Zhao, Junfeng Wang, Zhen Fan, Faming Zheng, Xingyu Zhou, Fang Xie, Jianping Zhang, Yihui Guan, Kui Yan, Zuhai Lei, Qinyue Wang, Luting Wang, Xiao Xiao, Hairong Zheng, Liang Chen, Cong Li, Ying Qing Mao

Cell Reports Medicine

DOI

2025

Artificial Intelligent‐Enhanced Metabolite Profiling for Intraoperative IDH1 Genotyping in Glioma Using an Orthogonally Responsive SERS Probe

Hang Yin, Xin Zhang, Zheng Feng Zhao, Chong Cao, Minhua Xu, Suhongrui Zhou, Tian Xuan, Ziyi Jin, Limei Han, Yang Fan, Cong Wang, Xiao Zhu, Ying Mao, Jinhua Yu, Cong Li

Advanced Science

DOI

2025

Imaging strategies for delineating glioma margins: Aiming at precise therapy

Jun Ming Tang, Liangpeng Chen, Ziyang Li, Cong Li, Deling Li

Fundamental Research

DOI

2025

Epilepsy therapy beyond neurons: Unveiling astrocytes as cellular targets

Yuncan Chen, Jiayi Hu, Ying Zhang, Lulu Peng, Xiaoyu Li, Cong Li, Xunyi Wu, Cong Wang

Neural Regeneration Research

DOI

2024

TriFNet: A triple-branch feature fusion network for pH determination by surface-enhanced Raman spectroscopy

Zheng Feng Zhao, Ziyi Jin, Guoqing Wu, Cong Li, Jinhua Yu

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy

DOI

2024

pH Mapping of Gliomas Using Quantitative Chemical Exchange Saturation Transfer MRI : Quasi‐Steady‐State, Spillover‐, and MT ‐Corrected Omega Plot Analysis

Ying Liu, Yin Wu, Yang Ji, Botao Zhao, Ziyi Jin, Shenghong Ju, Ying‐Hua Chu, Patrick Alexander Liebig, He Wang, Cong Li, Xiao‐Yong Zhang

Journal of Magnetic Resonance Imaging

DOI

2023

Visualizing Macrophage Phenotypes and Polarization in Diseases: From Biomarkers to Molecular Probes

Dan Ni, Heqing Zhou, Pengwei Wang, Fulin Xu, Cong Li

Phenomics

DOI

2023

A Ratiometric SERS Probe for Imaging the Macrophage Phenotypes in Live Mice with Epilepsy and Brain Tumor

Wenjia Duan, Cong Wang, Yiqing Jiang, An Sui, Zhi Li, Lu Wang, Zuhai Lei, Silvio Aime, Jinhua Yu, Cong Li

Advanced Healthcare Materials

DOI

2023

Intra‐Operative Definition of Glioma Infiltrative Margins by Visualizing Immunosuppressive Tumor‐Associated Macrophages

Chong Cao, Hang Yin, Biao Yang, Qi Yue, Guoqing Wu, Meng Gu, Yuwen Zhang, Fan Yang, Xiaoyan Dong, Ting Wang, Cong Wang, Xiao Zhu, Ying Qing Mao, Xiao‐Yong Zhang, Zuhai Lei, Cong Li

Advanced Science

DOI

2023

Fluorescence microscopic platforms imaging mitochondrial abnormalities in neurodegenerative diseases

Yicheng Wang, Pengwei Wang, Cong Li

Advanced Drug Delivery Reviews

DOI

2023

Forum on Materials for Brain Research

Ying Qing Mao, Cong Li, Chunhai Fan, Kirk S. Schanze, Laura E. Fernandez

ACS Applied Materials & Interfaces

DOI

2022

Tailoring Materials for Epilepsy Imaging: From Biomarkers to Imaging Probes

Jing Zhao, Cong Wang, Wanbing Sun, Cong Li

Advanced Materials

DOI

2022

Guiding Epilepsy Surgery with an LRP1-Targeted SPECT/SERRS Dual-Mode Imaging Probe

Zhi Li, Wanbing Sun, Wenjia Duan, Yiqing Jiang, Ming Chen, Guorong Lin, Qinyue Wang, Zhen Fan, Yusheng Tong, Luo Chen, Luo Chen, Jianing Li, Guangli Cheng, Cong Wang, Cong Li, Liang Chen, Liang Chen

ACS Applied Materials & Interfaces

DOI

2022

Emergence of Responsive Surface‐Enhanced Raman Scattering Probes for Imaging Tumor‐Associated Metabolites

Hang Hubert Yin, Ziyi Jin, Wenjia Duan, Bing Han, Limei Han, Cong Li

Advanced Healthcare Materials

DOI

2022

Intelligent SERS Navigation System Guiding Brain Tumor Surgery by Intraoperatively Delineating the Metabolic Acidosis

Ziyi Jin, Qi Yue, Wenjia Duan, An Sui, Botao Zhao, Yinhui Deng, Yuting Zhai, Yuwen Zhang, Tao Sun, Guang‐Ping Zhang, Limei Han, Ying Qing Mao, Jinhua Yu, Xiao‐Yong Zhang, Cong Li

Advanced Science

DOI

2021

Preliminary demonstration of in vivo quasi‐steady‐state CEST postprocessing—Correction of saturation time and relaxation delay for robust quantification of tumor MT and APT effects

Xiao‐Yong Zhang, Yuting Zhai, Ziyi Jin, Cong Li, Phillip Zhe Sun, Yin Wu

Magnetic Resonance in Medicine

DOI

2021

Reprogramming the immunosuppressive microenvironment of IDH1 wild-type glioblastoma by blocking Wnt signaling between microglia and cancer cells

Dandan Fan, Qi Yue, Jian Chen, Cong Wang, Ruilin Yu, Ziyi Jin, Shujie Yin, Qinyue Wang, Chen Luo, Luo Chen, Xueling Liao, Chengyuan Peng, Jianpin Zhang, Ying Qing Mao, Ying Mao, Ruimin Huang, Liang Chen, Liang Chen, Cong Li

OncoImmunology

DOI

2021

Unsymmetrical pentamethine cyanines for visualizing physiological acidities from the whole-animal to the cellular scale with pH-responsive deep-red fluorescence

Yicheng Wang, Zuhai Lei, Cong Wang, Chong Cao, Jiayi Hu, Ling Du, Limei Han, Cong Li

RSC Advances

DOI

2020

Imaging epileptic foci in mouse models via a low-density lipoprotein receptor-related protein-1 targeting strategy

Cong Wang, Jianping Zhang, Shaoli Song, Zhi Li, Shujie Yin, Wenjia Duan, Zixuan Wei, Ming Qi, Wanbing Sun, Lu Zhang, Chen Luo, Chen Luo, Xihui Gao, Ying Qing Mao, Hao Wang, Liang Chen, Liang Chen, Cong Li

EBioMedicine

DOI

2020

An electric-field-responsive paramagnetic contrast agent enhances the visualization of epileptic foci in mouse models of drug-resistant epilepsy

Cong Wang, Wanbing Sun, Jun Zhang, Jianping Zhang, Qinghua Guo, Xingyu Zhou, Dandan Fan, Haoran Liu, Ming Qi, Xihui Gao, Haiyan Xu, Zhaobing Gao, Mei Tian, Hong Zhang, Jianhong Wang, Zixuan Wei, Nicholas J. Long, Ying Qing Mao, Cong Li

Nature Biomedical Engineering

DOI

2020

A pH ratiometrically responsive surface enhanced resonance Raman scattering probe for tumor acidic margin delineation and image-guided surgery

Wenjia Duan, Qi Yue, Ying Liu, Yunfei Zhang, Qinghua Guo, Cong Wang, Shujie Yin, Dandan Fan, Wenjing Xu, Jiexian Zhuang, Jiachao Gong, Xinwei Li, Ruimin Huang, Liang Chen, Silvio Aime, Zhongliang Wang, Jianfeng Feng, Ying Mao, Xiao‐Yong Zhang, Cong Li

Chemical Science

DOI

2019

Surface-Enhanced Resonance Raman Scattering-Guided Brain Tumor Surgery Showing Prognostic Benefit in Rat Models

Limei Han, Wenjia Duan, Xinwei Li, Cong Wang, Ziyi Jin, Yuting Zhai, Chong Cao, Chen Luo, Wenjing Xu, Ying Liu, Yong‐Yan Bi, Jianfeng Feng, Ying Qing Mao, Qi Yue, Xiao‐Yong Zhang, Cong Li

ACS Applied Materials & Interfaces

DOI

2019

Photoacoustic Therapy for Precise Eradication of Glioblastoma with a Tumor Site Blood–Brain Barrier Permeability Upregulating Nanoparticle

Liming Liu, Qun Chen, Liewei Wen, Cong Li, Huan Qin, Da Xing

Advanced Functional Materials

DOI

2018

Custom‐Made Ceria Nanoparticles Show a Neuroprotective Effect by Modulating Phenotypic Polarization of the Microglia

Feng Zeng, Yingwei Wu, Xinwei Li, Xiaojiao Ge, Qinghua Guo, Xiaobing Lou, Zhonglian Cao, Bingwen Hu, Nicholas J. Long, Ying Qing Mao, Cong Li

Angewandte Chemie

DOI

2018

Image-guided chemotherapy with specifically tuned blood brain barrier permeability in glioma margins

Xihui Gao, Qi Yue, Yikang Liu, Dandan Fan, Kun Fan, Sihan Li, Jun Qian, Limei Han, Fang Fang, Fulin Xu, Daoying Geng, Liang Chen, Xin Hua Zhou, Ying Qing Mao, Cong Li

Theranostics

DOI

2018

Peptide-Functionalized Nanoinhibitor Restrains Brain Tumor Growth by Abrogating Mesenchymal-Epithelial Transition Factor (MET) Signaling

Yingwei Wu, Qi Wen Fan, Feng Zeng, Jinyu Zhu, Jian Chen, Dandan Fan, Xinwei Li, Wenjia Duan, Qinghua Guo, Zhonglian Cao, Karen C Briley-Saebo, Cong Li, Xiaofeng Tao

Nano Letters

DOI

2017

Guiding Brain‐Tumor Surgery via Blood–Brain‐Barrier‐Permeable Gold Nanoprobes with Acid‐Triggered MRI/SERRS Signals

Xihui Gao, Qi Yue, Zining Liu, Mengjing Ke, Xingyu Zhou, Sihan Li, Jianping Zhang, Ren Zhang, Liang Chen, Ying Qing Mao, Cong Li

Advanced Materials

DOI

2017

Edaravone-Encapsulated Agonistic Micelles Rescue Ischemic Brain Tissue by Tuning Blood-Brain Barrier Permeability

Qu Jin, Yu Chen Cai, Sihan Li, Haoran Liu, Xingyu Zhou, Chun‐Qiang Lu, Xihui Gao, Jun Qian, Jun Zhang, Shenghong Ju, Cong Li

Theranostics

DOI

2017

Single-wavelength excited photoacoustic-fluorescence microscopy for in vivo pH mapping

Baoyun Yan, Huan Qin, Cuiyun Huang, Cong Li, Qun Chen, Da Xing

Optics Letters

DOI

2017

An EGFRvIII targeted dual-modal gold nanoprobe for imaging-guided brain tumor surgery

Qi Yue, Xihui Gao, Yang Yu, Yang Li, Wei Hua, Kun Fan, Ren Zhang, Jun Qian, Liang Chen, Cong Li, Ying Mao

Nanoscale

DOI

2016

Nanoagonist-mediated endothelial tight junction opening: A strategy for safely increasing brain drug delivery in mice

Xihui Gao, Yuancheng Wang, Yikang Liu, Qi Yue, Zining Liu, Mengjing Ke, Shengyuan Zhao, Cong Li

Journal of Cerebral Blood Flow & Metabolism

DOI

2016

Enhancing sensitivity of SERRS nanoprobes by modifying heptamethine cyanine-based reporter molecules

Yunfei Zhang, Danqi Li, Xingyu Zhou, Xihui Gao, Shengyuan Zhao, Cong Li

Journal of Innovative Optical Health Sciences

DOI

2016

Selective imaging and cancer cell death via pH switchable near-infrared fluorescence and photothermal effects

Jingye Zhang, Zining Liu, Peng Lian, Jun Qian, Xinwei Li, Lu Wang, Wei Fu, Liang Chen, Xunbin Wei, Cong Li

Chemical Science

DOI

2016

Near-infrared asymmetrical heptamethine cyanines specifically imaging cancer cells by sensing their acidic lysosomal lumen

Rui Xi, Jing‐ye Zhang, Yunfei Zhang, Sihan Li, Yang Li, Xinwei Li, Liang Chen, Cong Li

RSC Advances

DOI

2015

Salvaging brain ischemia by increasing neuroprotectant uptake via nanoagonist mediated blood brain barrier permeability enhancement

Shuyan Zheng, Ying-Ying Bai, Yikang Liu, Xihui Gao, Yan Li, Yinzhi Changyi, Yuancheng Wang, Di Chang, Shenghong Ju, Cong Li

Biomaterials

DOI

2015

Multi-parametric imaging of the invasiveness-permissive acidic microenvironment in human glioma xenografts

Cuiyun Huang, Huan Qin, Jun Qian, Jingye Zhang, Shengyuan Zhao, Yinzhi Changyi, Bingbing Li, Jianping Zhang, Jianhua Zhu, Da Xing, Sihua Yang, Cong Li

RSC Advances

DOI

2014

Overcoming the Blood–Brain Barrier for Delivering Drugs into the Brain by Using Adenosine Receptor Nanoagonist

Xihui Gao, Jun Qian, Shuyan Zheng, Yinzhi Changyi, Jianping Zhang, Shenghong Ju, Jianhua Zhu, Cong Li

ACS Nano

DOI

2014

Evaluating tumor metastatic potential by imaging intratumoral acidosis via p H ‐activatable near‐infrared fluorescent probe

Lu Wang, Zhichao Fan, Jingye Zhang, Yinzhi Changyi, Cuiyun Huang, Yanjuan Gu, Ziyao Xu, Zhijia Tang, Weiyue Lu, Xunbin Wei, Cong Li

International Journal of Cancer

DOI

2014

Multimodal Nanoprobes Evaluating Physiological Pore Size of Brain Vasculatures in Ischemic Stroke Models

Shuyan Zheng, Yingying Bai, Yinzhi Changyi, Xihui Gao, Wenqing Zhang, Yuancheng Wang, Lu Zhou, Shenghong Ju, Cong Li

Advanced Healthcare Materials

DOI

2014

pH-responsive near-infrared nanoprobe imaging metastases by sensing acidic microenvironment

Zhan Si, Cuiyun Huang, Xihui Gao, Cong Li

RSC Advances

DOI

2013

Up-regulating Blood Brain Barrier Permeability of Nanoparticles via Multivalent Effect

Xihui Gao, Jun Qian, Shuyan Zheng, Ying Xiong, Jiahao Man, Binxin Cao, Lu Wang, Shenghong Ju, Cong Li

Pharmaceutical Research

DOI

2012

A cyanine based fluorophore emitting both single photon near-infrared fluorescence and two-photon deep red fluorescence in aqueous solution

Lu Wang, Jiefu Jin, Xishan Chen, Hai-Hua Fan, Billy King Fai Li, Kok‐Wai Cheah, Ning Ding, Shenghong Ju, Wing‐Tak Wong, Cong Li

Organic & Biomolecular Chemistry

DOI

2011

Two-Order Targeted Brain Tumor Imaging by Using an Optical/Paramagnetic Nanoprobe across the Blood Brain Barrier

Huihui Yan, Lu Wang, Jiyao Wang, Xiaofu Weng, Hao Chuan Lei, Xuxia Wang, Lu Jiang, Jianhua Zhu, Weiyue Lu, Xunbin Wei, Cong Li

ACS Nano

DOI

2011

Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier

Huihui Yan, Jiyao Wang, Peiwei Yi, Hao Chuan Lei, Changyou Zhan, Cao Xie, Linglin Feng, Jun Qian, Jianhua Zhu, Weiyue Lu, Cong Li

Chemical Communications

DOI

2011

pH responsive fluorescence nanoprobe imaging of tumors by sensing the acidic microenvironment

Lu Wang, Cong Li

Journal of Materials Chemistry

DOI

2010

pH‐Activated Near‐Infrared Fluorescence Nanoprobe Imaging Tumors by Sensing the Acidic Microenvironment

Cong Li, Jinsong Xia, Xunbin Wei, Huihui Yan, Zhan Si, Shenghong Ju

Advanced Functional Materials

DOI

2010

Dextran based pH-activated near-infrared fluorescence nanoprobe imaging the acidic compartments in cancer cells

Cong Li, Kai Li, Huihui Yan, Guanghui Li, Jinsong Xia, Xunbin Wei

Chemical Communications

DOI

精选作品

期刊论文

AI-Assisted SERS Decoding of Dual Enzymatic Activity for Intraoperative Chemical Mapping of Epilepsy

Cascade‐Amplified Ratiometric Fluorescent Probe for Time‐Locked Imaging Epilepsy

Adenosine 2A receptor drives microglial efferocytosis to accelerate white matter repair and functional recovery after stroke

An AI-assisted fluorescence microscopic system for screening mitophagy inducers by simultaneous analysis of mitophagic intermediates

Outside Back Cover: Tandem Dual‐Ratiometric SERS Probe Enables Raman Imaging of Neurological pH Fluctuations in Epilepsy (Angew. Chem. 25/2025)

Outside Back Cover: Tandem Dual‐Ratiometric SERS Probe Enables Raman Imaging of Neurological pH Fluctuations in Epilepsy (Angew. Chem. Int. Ed. 25/2025)

Tandem Dual‐Ratiometric SERS Probe Enables Raman Imaging of Neurological pH Fluctuations in Epilepsy

Edaravone-Encapsulated Agonistic Micelles Rescue Ischemic Brain Tissue by Tuning Blood-Brain Barrier Permeability: Erratum

Tailoring imaging probes for defining glioma invasive margins: Tracing the molecular footprints of cancer cells

Adoptive macrophages suppress glioblastoma growth by reversing immunosuppressive microenvironment through programmed phenotype repolarization

CRISPR/Cas9-Engineered Triple-Fusion Reporter Gene Imaging System for Monitoring Transplanted Neural Progenitor Cells in Ischemic Stroke

Ultrabright ratiometric Raman-guided epilepsy surgery by intraoperatively visualizing proinflammatory microglia

Artificial Intelligent‐Enhanced Metabolite Profiling for Intraoperative IDH1 Genotyping in Glioma Using an Orthogonally Responsive SERS Probe

Imaging strategies for delineating glioma margins: Aiming at precise therapy

Epilepsy therapy beyond neurons: Unveiling astrocytes as cellular targets

TriFNet: A triple-branch feature fusion network for pH determination by surface-enhanced Raman spectroscopy

pH Mapping of Gliomas Using Quantitative Chemical Exchange Saturation Transfer MRI : Quasi‐Steady‐State, Spillover‐, and MT ‐Corrected Omega Plot Analysis

Visualizing Macrophage Phenotypes and Polarization in Diseases: From Biomarkers to Molecular Probes

A Ratiometric SERS Probe for Imaging the Macrophage Phenotypes in Live Mice with Epilepsy and Brain Tumor

Intra‐Operative Definition of Glioma Infiltrative Margins by Visualizing Immunosuppressive Tumor‐Associated Macrophages

Fluorescence microscopic platforms imaging mitochondrial abnormalities in neurodegenerative diseases

Forum on Materials for Brain Research

Tailoring Materials for Epilepsy Imaging: From Biomarkers to Imaging Probes

Guiding Epilepsy Surgery with an LRP1-Targeted SPECT/SERRS Dual-Mode Imaging Probe

Emergence of Responsive Surface‐Enhanced Raman Scattering Probes for Imaging Tumor‐Associated Metabolites

Intelligent SERS Navigation System Guiding Brain Tumor Surgery by Intraoperatively Delineating the Metabolic Acidosis

Preliminary demonstration of in vivo quasi‐steady‐state CEST postprocessing—Correction of saturation time and relaxation delay for robust quantification of tumor MT and APT effects

Reprogramming the immunosuppressive microenvironment of IDH1 wild-type glioblastoma by blocking Wnt signaling between microglia and cancer cells

Unsymmetrical pentamethine cyanines for visualizing physiological acidities from the whole-animal to the cellular scale with pH-responsive deep-red fluorescence

Imaging epileptic foci in mouse models via a low-density lipoprotein receptor-related protein-1 targeting strategy

An electric-field-responsive paramagnetic contrast agent enhances the visualization of epileptic foci in mouse models of drug-resistant epilepsy

A pH ratiometrically responsive surface enhanced resonance Raman scattering probe for tumor acidic margin delineation and image-guided surgery

Surface-Enhanced Resonance Raman Scattering-Guided Brain Tumor Surgery Showing Prognostic Benefit in Rat Models

Photoacoustic Therapy for Precise Eradication of Glioblastoma with a Tumor Site Blood–Brain Barrier Permeability Upregulating Nanoparticle

Custom‐Made Ceria Nanoparticles Show a Neuroprotective Effect by Modulating Phenotypic Polarization of the Microglia

Image-guided chemotherapy with specifically tuned blood brain barrier permeability in glioma margins

Peptide-Functionalized Nanoinhibitor Restrains Brain Tumor Growth by Abrogating Mesenchymal-Epithelial Transition Factor (MET) Signaling

Guiding Brain‐Tumor Surgery via Blood–Brain‐Barrier‐Permeable Gold Nanoprobes with Acid‐Triggered MRI/SERRS Signals

Edaravone-Encapsulated Agonistic Micelles Rescue Ischemic Brain Tissue by Tuning Blood-Brain Barrier Permeability

Single-wavelength excited photoacoustic-fluorescence microscopy for in vivo pH mapping

An EGFRvIII targeted dual-modal gold nanoprobe for imaging-guided brain tumor surgery

Nanoagonist-mediated endothelial tight junction opening: A strategy for safely increasing brain drug delivery in mice

Enhancing sensitivity of SERRS nanoprobes by modifying heptamethine cyanine-based reporter molecules

Selective imaging and cancer cell death via pH switchable near-infrared fluorescence and photothermal effects

Near-infrared asymmetrical heptamethine cyanines specifically imaging cancer cells by sensing their acidic lysosomal lumen

Salvaging brain ischemia by increasing neuroprotectant uptake via nanoagonist mediated blood brain barrier permeability enhancement

Multi-parametric imaging of the invasiveness-permissive acidic microenvironment in human glioma xenografts

Overcoming the Blood–Brain Barrier for Delivering Drugs into the Brain by Using Adenosine Receptor Nanoagonist

Evaluating tumor metastatic potential by imaging intratumoral acidosis via p H ‐activatable near‐infrared fluorescent probe

Multimodal Nanoprobes Evaluating Physiological Pore Size of Brain Vasculatures in Ischemic Stroke Models

pH-responsive near-infrared nanoprobe imaging metastases by sensing acidic microenvironment

Up-regulating Blood Brain Barrier Permeability of Nanoparticles via Multivalent Effect

A cyanine based fluorophore emitting both single photon near-infrared fluorescence and two-photon deep red fluorescence in aqueous solution

Two-Order Targeted Brain Tumor Imaging by Using an Optical/Paramagnetic Nanoprobe across the Blood Brain Barrier

Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier

pH responsive fluorescence nanoprobe imaging of tumors by sensing the acidic microenvironment

pH‐Activated Near‐Infrared Fluorescence Nanoprobe Imaging Tumors by Sensing the Acidic Microenvironment

Dextran based pH-activated near-infrared fluorescence nanoprobe imaging the acidic compartments in cancer cells

会议论文

靶向调控血脑屏障通透性提高脑卒中神经保护疗效（英文）

预印本

Adoptive macrophages reverse the immunosuppressive microenvironment in glioblastoma via programmed phenotypic polarization

书籍章节

Tumor Diagnosis Patterns

Savaging brain ischemia by increasing brain uptake of neuroprotectants

研究方向