石晓静｜郑州大学｜学者主页

2026

Overexpression of TFPI‐2 Suppresses Colorectal Cancer Progression by Inducing Ferroptosis via NF‐κB Signaling

Xiaojing Shi, Jing Zhang, Jian-Nan Lu, Zheng Xu

Journal of biochemical and molecular toxicology

2025

ROS-induced cytosolic release of mitochondrial PGAM5 promotes colorectal cancer progression by interacting with MST3

Shiyang Wang, Xi Wu, Wenxin Bi, Jiu-Zhi Xu, Liyuan Hou, Guilin Li, Yu-Wei Pan, Han-Fu Zhang, Mengzhen Li, Sujuan Du, Mingxin Zhang, Di Liu, Shuiling Jin, Xiaojing Shi, Yuhua Tian, Jian-Wei Shuai, M. Plikus, Mo-Shi Song, Zhao-Cai Zhou, Lu Yu, Cong Lv, Zheng-Quan Yu

Nature Communications

精选作品

期刊论文

Overexpression of TFPI‐2 Suppresses Colorectal Cancer Progression by Inducing Ferroptosis via NF‐κB Signaling

ROS-induced cytosolic release of mitochondrial PGAM5 promotes colorectal cancer progression by interacting with MST3

Correction to "Discovery of Novel 5-Cyano-3-phenylindole-Based LSD1/HDAC Dual Inhibitors for Colorectal Cancer Treatment".

DNA replication stress underpins the vulnerability to oxidative phosphorylation inhibition in colorectal cancer

Single-cell analysis reveals that GFAP+ dedifferentiated Schwann cells promote tumor progress in PNI-positive distal cholangiocarcinoma via lactate/HMGB1 axis

Inhibition of Skp2 enhances anti-tumor immunity of macrophages by regulating CD47 in gastric cancer

Estrogen Promotes the Proliferation and Migration of Endometrial Cancer Through the GPER‐Mediated NOTCH Pathway

IGFBP2 Promotes Proliferation and Glycolysis of Endometrial Cancer by Regulating PKM2 / HIF ‐1α Axis

Discovery of Novel [1,2,4]Triazolo[1,5-a]pyrimidine Derivatives as Novel Potent S-Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer.

Discovery of Novel 5-Cyano-3-phenylindole-Based LSD1/HDAC Dual Inhibitors for Colorectal Cancer Treatment.

HER2+ advanced gastric cancer: Current state and opportunities (Review)

Discovery of Novel 1,3-Diphenylpyrazine Derivatives as Potent S-Phase Kinase-Associated Protein 2 (Skp2) Inhibitors for the Treatment of Cancer

Discovery of novel, potent, and orally bioavailable HDACs inhibitors with LSD1 inhibitory activity for the treatment of solid tumors

Skp2 is a novel regulator of LSD1 expression and function in gastric cancer

A comprehensive review of SHP2 and its role in cancer

Discovery of the antitumor activities of a potent DCN1 inhibitor compound 383 targeting LSD1 in gastric cancer

Publisher Correction: Establishment of high-throughput screening HTRF assay for identification small molecule inhibitors of Skp2-Cks1

Establishment of high-throughput screening HTRF assay for identification small molecule inhibitors of Skp2-Cks1

Myofibroblast Deficiency of LSD1 Alleviates TAC-Induced Heart Failure

Research progress of dual inhibitors targeting crosstalk between histone epigenetic modulators for cancer therapy

Microbial profiling identifies potential key drivers in gastric cancer patients

Discovery of tofacitinib derivatives as orally active antitumor agents based on the scaffold hybridization strategy

Skp2 in the ubiquitin‐proteasome system: A comprehensive review

RICTOR/mTORC2 affects tumorigenesis and therapeutic efficacy of mTOR inhibitors in esophageal squamous cell carcinoma

Discovery of [1,2,3]triazolo[4,5-d]pyrimidine derivatives as highly potent, selective, and cellularly active USP28 inhibitors

The role of deubiquitinating enzymes in gastric cancer (Review)

Discovery of WS-157 as a highly potent, selective and orally active EGFR inhibitor

Development of Highly Potent, Selective, and Cellular Active Triazolo[1,5-a]pyrimidine-Based Inhibitors Targeting the DCN1–UBC12 Protein–Protein Interaction

A novel ent-kaurane diterpenoid analog, DN3, selectively kills human gastric cancer cells via acting directly on mitochondria

Pro-Apoptotic Effects of JDA-202, a Novel Natural Diterpenoid, on Esophageal Cancer Through Targeting Peroxiredoxin I

Design, synthesis, and preliminary evaluation of the biological activity of dithiocarbamate-3-epi-jaspine B hybrids

Structurally novel steroidal spirooxindole by241 potently inhibits tumor growth mainly through ROS-mediated mechanisms

Efficient synthesis of new antiproliferative steroidal hybrids using the molecular hybridization approach

六神丸抑制AOM/DSS诱导小鼠炎症相关性结直肠癌的作用

Efficient synthesis of novel antiproliferative steroidal spirooxindoles via the [3+2] cycloaddition reactions of azomethine ylides

A Systematic Review of Histone Lysine‐Specific Demethylase 1 and Its Inhibitors

Jaridonin-induced G2/M phase arrest in human esophageal cancer cells is caused by reactive oxygen species-dependent Cdc2-tyr15 phosphorylation via ATM–Chk1/2–Cdc25C pathway

Corrigendum to: “Design, synthesis and biological evaluation of novel steroidal spiro-oxindoles as potent antiproliferative agents” [J. Steroid Biochem. Mol. Biol. 141 (2014) 121–134]

Synthesis and preliminary biological evaluation of 1,2,3-triazole-Jaspine B hybrids as potential cytotoxic agents

新型对映-贝壳杉烷二萜化合物jaridonin体外抗肿瘤活性及其作用机制探讨

A novel [1,2,4] triazolo [1,5-a] pyrimidine-based phenyl-linked steroid dimer: Synthesis and its cytotoxic activity

Stereoselective synthesis of novel antiproliferative steroidal (E, E) dienamides through a cascade aldol/cyclization process

Design and synthesis of novel 1,2,3-triazole-dithiocarbamate hybrids as potential anticancer agents

会议论文

OP46诱导人胃癌细胞MGC-803 G2/M期阻滞及其机制的研究

血清饥饿法用于人食管癌细胞周期归一化的方法学研究

抗肿瘤新药JD27通过线粒体途径诱导食管癌EC9706细胞凋亡

抗肿瘤新药JYD207诱导人食管癌细胞自噬及其机制的研究

研究方向