赵利｜苏州大学｜学者主页

2026

Ultrasmall-in-nano hybrid boron-gold architectures for enhanced boron delivery toward boron neutron capture therapy.

Federico Purificato, V. Frusca, Gloria Pizzoli, A. Ayub, E. Mugnaioli, P. Sarogni, Giuliana Drava, Yao-Yao Da, N. Komatsu, Li Zhao, Valerio Voliani

Chemical Communications

DOI

2026

Palladium‐Based Nanozymes: From Synthesis and Activity Modulation to Biomedical Applications

Yijun Fang, Yao Liu, Zhibing Tang, Ziyu Zhang, Xiaojun Yang, Xiangyi Li, Li Zhao, Yu Chong

Chemistry - A European Journal

DOI

2024

Targeted sonodynamic therapy induces tumor cell quasi-immunogenic ferroptosis and macrophage immunostimulatory autophagy in glioblastoma.

Meng-Fei Wang, Jie Guo, Shen-Jun Yuan, Ke Li, Quan Zhang, Hui-Mei Lei, Jia-Lin Wu, Li Zhao, Yonghong Xu, Xiao Chen

Biomaterials

DOI

2023

PD-L1 blockade TAM-dependently potentiates mild photothermal therapy against triple-negative breast cancer

Chao Wang, Yonghong Xu, Huazhen Xu, Ke Li, Quan Zhang, Lin Shi, Li Zhao, Xiao Chen

Journal of Nanobiotechnology

DOI

2023

Sonodynamic therapy of glioblastoma mediated by platelets with ultrasound-triggered drug release

Mei-Yao Wang, Huazhen Xu, Tongfei Li, Ke Li, Quan Zhang, Siyi Chen, Li Zhao, Jin-Cao Chen, Xiao Chen

Drug Delivery

DOI

2023

Laser-triggered intelligent drug delivery and anti-cancer photodynamic therapy using platelets as the vehicle

Qi-Rui Li, Huazhen Xu, Rong-Cheng Xiao, Bin Liu, Tian-Qi Ma, Tingting Yu, Liu-Gen Li, Mei-Fang Wang, Li Zhao, Xiao Chen, Tong-Fei Li

Platelets

DOI

2023

Tumor Eradication by Boron Neutron Capture Therapy with 10B‐enriched Hexagonal Boron Nitride Nanoparticles Grafted with Poly(Glycerol)

Yucai Zhang, H. Kang, Huazhen Xu, Hong Luo, Minoru Suzuki, Qing Lan, Xiao Chen, N. Komatsu, Li Zhao

Advances in Materials

DOI

2022

Platelets are highly efficient and efficacious carriers for tumor-targeted nano-drug delivery

Qi-Rui Li, Huazhen Xu, Rong-Cheng Xiao, Yang Liu, Jun-Ming Tang, J. Li, Tingting Yu, Bin Liu, Liu-Gen Li, Mei-Fang Wang, Ning Han, Yonghong Xu, Chao Wang, N. Komatsu, Li Zhao, Xing-Chun Peng, Tong-Fei Li, Xiao Chen

Drug Delivery

DOI

2022

Harnessing chlorin e6 loaded by functionalized iron oxide nanoparticles linked with glucose for target photodynamic therapy and improving of the immunogenicity of lung cancer

Tingting Yu, Xing-Chun Peng, Mei-Fang Wang, Ning Han, Huazhen Xu, Qi-Rui Li, Liu-Gen Li, Xiang Xu, Qian-Li Ma, Bin Liu, Jue Wang, Li Zhao, Xiao Chen, Tong-Fei Li

Journal of Cancer Research and Clinical Oncology

DOI

2022

Targeted photodynamic therapy of glioblastoma mediated by platelets with photo-controlled release property.

Huazhen Xu, Tong-Fei Li, Yan Ma, Ke Li, Quan Zhang, Yonghong Xu, Yucai Zhang, Li Zhao, Xiao Chen

Biomaterials

DOI

2022

Rational surface modification of gadolinium borate nanoparticles enhancing colloidal stability in physiological media for potential neutron capture therapy and magnetic resonance imaging.

Yucai Zhang, Cheng Qian, Daochang Li, Li Zhao

Colloids and Surfaces B: Biointerfaces

DOI

2021

Synergy of nanodiamond–doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells

Huazhen Xu, Tong-Fei Li, Chao Wang, Yan Ma, Yang Liu, M. Zheng, Zhang-Lin Liu, Jin-Bo Chen, Ke Li, Shibao Sun, N. Komatsu, Yonghong Xu, Li Zhao, Xiao Chen

Journal of Nanobiotechnology

DOI

2021

Efficient Delivery of Chlorin e6 by Polyglycerol-Coated Iron Oxide Nanoparticles with Conjugated Doxorubicin for Enhanced Photodynamic Therapy of Melanoma.

Tong-Fei Li, Huazhen Xu, Yonghong Xu, Tingli Yu, Jun-Ming Tang, Ke Li, Chao Wang, Xing-Chun Peng, Qi-Rui Li, Xue Sang, M. Zheng, Y. Liu, Li Zhao, Xiao Chen

Molecular Pharmaceutics

DOI

2021

Surface-engineered carbon nanohorns as a theranostic nanodevice for photoacoustic imaging and effective radiochemotherapy of cancer

Daochang Li, Yucai Zhang, Jing Xu, Fumi Yoshino, Huazhen Xu, Xiao Chen, Li Zhao

DOI

2021

SPECT imaging and highly efficient therapy of rheumatoid arthritis based on hyperbranched semiconducting polymer nanoparticles.

Qin Zhang, Daochang Li, Jing Zhong, Yanglin Wu, Yu-Cheng Shi, Hui-Lin Yang, Li Zhao, Kai Yang, Jun Lin

Biomaterials Science

DOI

2021

Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin.

Shen-Jun Yuan, Chao Wang, Huazhen Xu, Yan Liu, M. Zheng, Ke Li, Shiqi Sun, N. Komatsu, Li Zhao, Xiao Chen

International journal of pharmaceutics

DOI

2020

Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.

Zhuo Chen, Shen-Jun Yuan, Ke Li, Quan Zhang, Tong-Fei Li, Hui-Chao An, Huazhen Xu, Yuan Yue, Min Han, Yonghong Xu, N. Komatsu, Li Zhao, Xiao Chen

Journal of Controlled Release

DOI

2020

Real-time nanodiamond thermometry probing in vivo thermogenic responses

M. Fujiwara, Si-Mo Sun, Alexander Dohms, Y. Nishimura, K. Suto, Y. Takezawa, K. Oshimi, Li Zhao, N. Sadzak, Y. Umehara, Y. Teki, N. Komatsu, O. Benson, Yutaka Shikano, E. Kage-Nakadai

Science Advances

DOI

2019

Doxorubicin-polyglycerol-nanodiamond composites stimulate glioblastoma cell immunogenicity through activation of autophagy.

Tong-Fei Li, Yonghong Xu, Ke Li, Chao Wang, Xin Liu, Yuan Yue, Zhuo Chen, Shen-Jun Yuan, Yu Wen, Quan Zhang, Min Han, N. Komatsu, Li Zhao, Xiao Chen

Acta Biomaterialia

DOI

2019

Doxorubicin-polyglycerol-nanodiamond conjugate is a cytostatic agent that evades chemoresistance and reverses cancer-induced immunosuppression in triple-negative breast cancer

Shen-Jun Yuan, Yonghong Xu, Chao Wang, Hui-Chao An, Huazhen Xu, Ke Li, N. Komatsu, Li Zhao, Xiao Chen

Journal of Nanobiotechnology

DOI

2019

Tumor Imaging: Preferential Tumor Accumulation of Polyglycerol Functionalized Nanodiamond Conjugated with Cyanine Dye Leading to Near‐Infrared Fluorescence In Vivo Tumor Imaging (Small 48/2019)

Fumi Yoshino, T. Amano, Yajuan Zou, Jian Xu, F. Kimura, Yoshio Furusho, T. Chano, Takashi Murakami, Li Zhao, N. Komatsu

Small

DOI

2019

Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.

Zhuo Chen, Chao Wang, Tong-Fei Li, Ke Li, Yuan Yue, Xin Liu, Huazhen Xu, Yu Wen, Quan Zhang, Min Han, N. Komatsu, Yonghong Xu, Li Zhao, Xiao Chen

Nanomedicine

DOI

2019

Magnetofluorescent nanohybrid comprising polyglycerol grafted carbon dots and iron oxides: Colloidal synthesis and applications in cellular imaging and magnetically enhanced drug delivery.

Yu Wen, Mei-Yun Xu, Xin Liu, Xiaoya Jin, Jiaqian Kang, Di Xu, Ho Sang, Peng Gao, Xiao Chen, Li Zhao

Colloids and Surfaces B: Biointerfaces

DOI

2019

Preferential Tumor Accumulation of Polyglycerol Functionalized Nanodiamond Conjugated with Cyanine Dye Leading to Near-Infrared Fluorescence In Vivo Tumor Imaging.

Fumi Yoshino, T. Amano, Yajuan Zou, Jian Xu, F. Kimura, Yoshio Furusho, T. Chano, Takashi Murakami, Li Zhao, N. Komatsu

Small

DOI

2018

Dendritic cell-mediated delivery of doxorubicin-polyglycerol-nanodiamond composites elicits enhanced anti-cancer immune response in glioblastoma.

Tong-Fei Li, Ke Li, Quan Zhang, Chao Wang, Yuan Yue, Zhuo Chen, Shen-Jun Yuan, Xin Liu, Yu Wen, Min Han, N. Komatsu, Yonghong Xu, Li Zhao, Xiao Chen

Biomaterials

DOI

2018

Monocyte-mediated chemotherapy drug delivery in glioblastoma.

Chao Wang, Ke Li, Tong-Fei Li, Zhuo Chen, Yu Wen, Xin Liu, Xuemei Jia, Yichao Zhang, Yonghong Xu, Min Han, N. Komatsu, Li Zhao, Xiao Chen

Nanomedicine

DOI

2018

Ultrasmall Hyperbranched Semiconducting Polymer Nanoparticles with Different Radioisotopes Labeling for Cancer Theranostics.

Xuan Yi, Mei-Yun Xu, Hailin Zhou, Saisai Xiong, Rui Qian, Z. Chai, Li Zhao, Kai Yang

ACS Nano

DOI

2018

Polyglycerol grafting and RGD peptide conjugation on MnO nanoclusters for enhanced colloidal stability, selective cellular uptake and cytotoxicity.

Xiao-Xin Yang, Li Zhao, Lu-Yi Zheng, Mei-Yun Xu, Xiu-Lan Cai

Colloids and Surfaces B: Biointerfaces

DOI

2017

Cationic Polyarginine Conjugated Mesoporous Bioactive Glass Nanoparticles with Polyglycerol Coating for Efficient DNA Delivery.

Xian Li, Li Zhao, Qi-Ming Liang, Jian-Dong Ye, N. Komatsu, Qing Zhang, Wen-Dong Gao, Mei-Yun Xu, Xiao-Feng Chen

Journal of Biomedical Nanotechnology

DOI

2017

Harnessing the Cross-talk between Tumor Cells and Tumor-associated Macrophages with a Nano-drug for modulation of Glioblastoma Immune Microenvironment

Tong-Fei Li, Ke Li, Chao Wang, Xin Liu, Yu Wen, Yonghong Xu, Quan Zhang, Qiu-ya Zhao, Ming Shao, Yan-Ze Li, Min Han, N. Komatsu, Li Zhao, Xiao Chen

bioRxiv

DOI

2017

Polyglycerol mediated covalent construction of magnetic mesoporous silica nanohybrid with aqueous dispersibility for drug delivery.

Xiao-Xin Yang, Yu Wen, Anqing Wu, Mei-Yun Xu, T. Amano, Lu-Yi Zheng, Li Zhao

Materials Science and Engineering C: Materials for Biological Applications

DOI

2016

Efficient delivery of chlorin e6 into ovarian cancer cells with octalysine conjugated superparamagnetic iron oxide nanoparticles for effective photodynamic therapy.

Li Zhao, Hongkuan Yang, T. Amano, Hongmei Qin, Lu-Yi Zheng, Akimasa Takahashi, Shiguang Zhao, I. Tooyama, Takashi Murakami, N. Komatsu

Journal of materials chemistry. B

DOI

赵利

精选作品

期刊论文

Ultrasmall-in-nano hybrid boron-gold architectures for enhanced boron delivery toward boron neutron capture therapy.

Palladium‐Based Nanozymes: From Synthesis and Activity Modulation to Biomedical Applications

Targeted sonodynamic therapy induces tumor cell quasi-immunogenic ferroptosis and macrophage immunostimulatory autophagy in glioblastoma.

PD-L1 blockade TAM-dependently potentiates mild photothermal therapy against triple-negative breast cancer

Sonodynamic therapy of glioblastoma mediated by platelets with ultrasound-triggered drug release

Laser-triggered intelligent drug delivery and anti-cancer photodynamic therapy using platelets as the vehicle

Tumor Eradication by Boron Neutron Capture Therapy with 10B‐enriched Hexagonal Boron Nitride Nanoparticles Grafted with Poly(Glycerol)

Platelets are highly efficient and efficacious carriers for tumor-targeted nano-drug delivery

Harnessing chlorin e6 loaded by functionalized iron oxide nanoparticles linked with glucose for target photodynamic therapy and improving of the immunogenicity of lung cancer

Targeted photodynamic therapy of glioblastoma mediated by platelets with photo-controlled release property.

Rational surface modification of gadolinium borate nanoparticles enhancing colloidal stability in physiological media for potential neutron capture therapy and magnetic resonance imaging.

Synergy of nanodiamond–doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells

Efficient Delivery of Chlorin e6 by Polyglycerol-Coated Iron Oxide Nanoparticles with Conjugated Doxorubicin for Enhanced Photodynamic Therapy of Melanoma.

Surface-engineered carbon nanohorns as a theranostic nanodevice for photoacoustic imaging and effective radiochemotherapy of cancer

SPECT imaging and highly efficient therapy of rheumatoid arthritis based on hyperbranched semiconducting polymer nanoparticles.

Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin.

Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.

Real-time nanodiamond thermometry probing in vivo thermogenic responses

Doxorubicin-polyglycerol-nanodiamond composites stimulate glioblastoma cell immunogenicity through activation of autophagy.

Doxorubicin-polyglycerol-nanodiamond conjugate is a cytostatic agent that evades chemoresistance and reverses cancer-induced immunosuppression in triple-negative breast cancer

Tumor Imaging: Preferential Tumor Accumulation of Polyglycerol Functionalized Nanodiamond Conjugated with Cyanine Dye Leading to Near‐Infrared Fluorescence In Vivo Tumor Imaging (Small 48/2019)

Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.

Magnetofluorescent nanohybrid comprising polyglycerol grafted carbon dots and iron oxides: Colloidal synthesis and applications in cellular imaging and magnetically enhanced drug delivery.

Preferential Tumor Accumulation of Polyglycerol Functionalized Nanodiamond Conjugated with Cyanine Dye Leading to Near-Infrared Fluorescence In Vivo Tumor Imaging.

Dendritic cell-mediated delivery of doxorubicin-polyglycerol-nanodiamond composites elicits enhanced anti-cancer immune response in glioblastoma.

Monocyte-mediated chemotherapy drug delivery in glioblastoma.

Ultrasmall Hyperbranched Semiconducting Polymer Nanoparticles with Different Radioisotopes Labeling for Cancer Theranostics.

Polyglycerol grafting and RGD peptide conjugation on MnO nanoclusters for enhanced colloidal stability, selective cellular uptake and cytotoxicity.

Cationic Polyarginine Conjugated Mesoporous Bioactive Glass Nanoparticles with Polyglycerol Coating for Efficient DNA Delivery.

Harnessing the Cross-talk between Tumor Cells and Tumor-associated Macrophages with a Nano-drug for modulation of Glioblastoma Immune Microenvironment

Polyglycerol mediated covalent construction of magnetic mesoporous silica nanohybrid with aqueous dispersibility for drug delivery.

Efficient delivery of chlorin e6 into ovarian cancer cells with octalysine conjugated superparamagnetic iron oxide nanoparticles for effective photodynamic therapy.

研究方向