涂怡｜武汉轻工大学｜学者主页

2025

癌症免疫反应中的代谢调节

Qi Wu, Xin Yu, Juanjuan Li, Shengrong Sun, Yi Tu

《癌症》

2023

Macrolide antibiotics activate the integrated stress response and promote tumor proliferation

Xin Yu, Ai-Ling Tian, P. Wang, Juan-Juan Li, Juan Wu, Bei Li, Zhou Liu, Siqing Liu, Zhijie Gao, Si Sun, Shengrong Sun, Yi Tu, Qi Wu

Cell Stress

DOI

2023

In situ Injection of pH- and Temperature-Sensitive Nanomaterials Increases Chemo-Photothermal Efficacy by Alleviating the Tumor Immunosuppressive Microenvironment [Retraction]

Jianhua Liu, Lian-Tao Guo, Y. Rao, Weijie Zheng, Dongcheng Gao, Jing Zhang, Lan Luo, Xinwen Kuang, S. Sukumar, Yi Tu, Chuang Chen, Shengrong Sun

International Journal of Nanomedicine

DOI

2022

DDOST调控抗病毒cGAS-MITA信号通路的分子机制

涂怡

《武汉大学》

2022

TLR与PI3K-Akt通路交互调控的研究进展

尹秀娟，涂怡，刘昱

《生物化工》

2022

High Glucose Accelerates Tumor Progression by Regulating MEDAG-Mediated Autophagy Levels in Breast Cancer

Chen-Yuan Li, Si Sun, Yi Tu, Hanpu Zhang, Feng Yao, Shi-Chong Liao, Shengrong Sun, Zhi-Yu Li, Zhong Wang

International Journal on Biological Sciences

DOI

2022

PSMD12 promotes the activation of the MEK-ERK pathway by upregulating KIF15 to promote the malignant progression of liver cancer

Hanpu Zhang, Chen-Yuan Li, Shi-Chong Liao, Yi Tu, Shengrong Sun, Feng Yao, Zhi-Yu Li, Zhong Wang

Cancer Biology & Therapy

DOI

2022

In situ Injection of pH- and Temperature-Sensitive Nanomaterials Increases Chemo-Photothermal Efficacy by Alleviating the Tumor Immunosuppressive Microenvironment

Jianhua Liu, Lian-Tao Guo, Y. Rao, Weijie Zheng, Dongcheng Gao, Jing Zhang, Lan Luo, Xinwen Kuang, S. Sukumar, Yi Tu, Chuang Chen, Shengrong Sun

International Journal of Nanomedicine

DOI

2022

Clinical and prognosis value of the number of metastatic lymph nodes in patients with papillary thyroid carcinoma

Ling Zhan, Hong-fang Feng, Xi-Zi Yu, Ling-Rui Li, Jun-Long Song, Yi Tu, Jing-ping Yuan, Chuang Chen, Shengrong Sun

BMC Surgery

DOI

2022

Differentiate Thermal Property of Mammary Glands for Precise Photothermal Therapy

Yuxin Fang, Weijie Zheng, Yuxuan Peng, Jianhua Liu, Jian-Shu Gao, Yi Tu, Shengrong Sun, Xiaona Huang, Jinjuan She, Chuang Chen, S. Xu, Y. Yue

Advances in Therapy

DOI

2021

MEDAG enhances breast cancer progression and reduces epirubicin sensitivity through the AKT/AMPK/mTOR pathway

Zhi-Yu Li, Chen-Yuan Li, Qi Wu, Yi Tu, Changhua Wang, Xin Yu, Bei Li, Zhong Wang, Si Sun, Shengrong Sun

Cell Death and Disease

DOI

2021

Exosomal microRNAs in cancer-related sarcopenia: Tumor-derived exosomal microRNAs in muscle atrophy

Chen-Yuan Li, Qi Wu, Zhi-Yu Li, Zhong Wang, Yi Tu, Chuang Chen, Si Sun, Shengrong Sun

Experimental biology and medicine

DOI

2021

Metabolic regulation in the immune response to cancer

Qi Wu, Xin Yu, Juan-Juan Li, Shengrong Sun, Yi Tu

Cancer Communications

DOI

2021

IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms

Qi Wu, Ai-Ling Tian, Bei Li, Marion Leduc, S. Forveille, P. Hamley, W. Galloway, Wei Xie, P. Liu, Li-Wei Zhao, Shuai Zhang, Pan Hui, F. Madeo, Yi Tu, O. Kepp, G. Kroemer

Journal for ImmunoTherapy of Cancer

DOI

2021

An Albumin-Based Therapeutic Nanosystem for Photosensitizer/Protein Co-Delivery to Realize Synergistic Cancer Therapy.

Shu-Lun Ai, Cai-Xia Wang, Yan Peng, Yi Tu, Jin-Ju Lei, Chang Xu, Xiao-he Ren, Si-Xue Cheng

ACS Applied Bio Materials

DOI

2021

AKT as a therapeutic target for autophagy induction and cancer therapy

Qi Wu, Yi Tu, G. Kroemer, O. Kepp

Oncoscience

DOI

2021

Ceramide kinase mediates intrinsic resistance and inferior response to chemotherapy in triple‐negative breast cancer by upregulating Ras/ERK and PI3K/Akt pathways

Shan Zhu, Yulin Xu, Li-Jun Wang, Shi-Chong Liao, Yuan Wang, Manman Shi, Yi Tu, Yu-Rong Zhou, Wen Wei

Cancer Cell International

DOI

2021

PSMD8 Promotes Breast Cancer Progression and Attenuates Paclitaxel Sensitivity by Regulating the Expression of KIF10

Zhi-Yu Li, Chen-Yuan Li, Yi Tu, Feng Yao, Shengrong Sun, Shi-Chong Liao, Zhong Wang

DOI

2021

Intraductal administration of N-methyl-N-nitrosourea as a novel rodent mammary tumor model

Dongcheng Gao, Jian-Hua Liu, Jingping Yuan, Juan Wu, Xinwen Kuang, De-Guang Kong, Weijie Zheng, Guannan Wang, S. Sukumar, Yi Tu, Chuang Chen, Shengrong Sun

Annals of Translational Medicine

DOI

2021

More Aggressive Cancer Behaviour in Thyroid Cancer Patients in the Post-COVID-19 Pandemic Era: A Retrospective Study

Hanqing Liu, Ling Zhan, Lianghua Guo, Xi-Zi Yu, Ling-Rui Li, Hong-fang Feng, Dan Yang, Zhi-Liang Xu, Yi Tu, Chuang Chen, Shengrong Sun

International Journal of General Medicine

DOI

2020

Patient-reported Outcomes of Patients With Breast Cancer During the COVID-19 Outbreak in the Epicenter of China: A Cross-sectional Survey Study

Juan-Juan Li, C. Santa-Maria, Hong-fang Feng, Ling-Chen Wang, Peng-Cheng Zhang, Yuan-Bing Xu, Yu-Yan Tan, Zhongchun Liu, Bo Du, Meng Lan, Qingfeng Yang, Feng Yao, Yi Tu, Shengrong Sun, Xing-Rui Li, Chuang Chen

Clinical Breast Cancer

DOI

2020

Appraisal of radioiodine refractory thyroid cancer: advances and challenges.

Hanqing Liu, Dan Yang, Ling-Rui Li, Yi Tu, Chuang Chen, Shengrong Sun

American Journal of Cancer Research

2020

Quality Analysis of Chinese Popular Scientific Articles Pertaining to Novel Coronavirus Pneumonia

Shi-Chong Liao, Shi-Chong Liao, Xin-Yue Chen, Yi Tu, Shengrong Sun, Shan Zhu, Jin-Xin Li

DOI

2020

Galeterone sensitizes breast cancer to chemotherapy via targeting MNK/eIF4E and β-catenin

Yulin Xu, Shi-Chong Liao, Li-Jun Wang, Yuan Wang, Wen Wei, Ke Su, Yi Tu, Shan Zhu

Cancer Chemotherapy and Pharmacology

DOI

2020

Isobacachalcone induces autophagy and improves the outcome of immunogenic chemotherapy

Qi Wu, Ai-Ling Tian, S. Durand, Fanny Aprahamian, Nitharsshini Nirmalathasan, Wei Xie, Peng Liu, Li-Wei Zhao, Shuai Zhang, Hui Pan, D. Carmona-Gutierrez, F. Madeo, Yi Tu, O. Kepp, G. Kroemer

Cell Death and Disease

DOI

2020

Clinical Characteristics and Outcomes of Single Versus Double Hormone Receptor-Positive Breast Cancer in 2 Large Databases.

Zhi-Yu Li, Yi Tu, Qi Wu, Zhong Wang, Juan-Juan Li, Yimin Zhang, Shengrong Sun

Clinical Breast Cancer

DOI

2020

Endoplasmic reticulum stress‐induced exosomal miR‐27a‐3p promotes immune escape in breast cancer via regulating PD‐L1 expression in macrophages

Xiao-Li Yao, Yi Tu, Yulin Xu, Yue-Yue Guo, Feng Yao, Xing-Hua Zhang

Journal of Cellular and Molecular Medicine

DOI

2020

Abstract S07-02: Patient-reported outcomes of breast cancer patients during the COVID-19 outbreak in the epicenter of China: A cross-sectional survey study

Juan-Juan Li, C. Santa-Maria, Hong-fang Feng, Ling-Chen Wang, Peng-Cheng Zhang, Yuangbing Xu, Yu-Yan Tan, Zhongchun Liu, Bo Du, Meng Lan, Qingfeng Yang, Feng Yao, Yi Tu, Shengrong Sun, Xing-Rui Li, Chuang Chen

DOI

2020

Endoplasmic reticulum stress confers 5-fluorouracil resistance in breast cancer cell via the GRP78/OCT4/lncRNA MIAT/AKT pathway.

Xiao-Li Yao, Yi Tu, Yulin Xu, Yue-Yue Guo, Feng Yao, Xing-Hua Zhang

American Journal of Cancer Research

2020

Interleukin-6 knockout reverses macrophage differentiation imbalance and alleviates cardiac dysfunction in aging mice

Yuan Wang, Shan Zhu, Wen Wei, Yi Tu, Chuang Chen, Jun-Long Song, Juan-Juan Li, Changhua Wang, Zhi-Liang Xu, Shengrong Sun

Aging

DOI

2019

Thyroxine Alleviates Energy Failure, Prevents Myocardial Cell Apoptosis, and Protects against Doxorubicin-Induced Cardiac Injury and Cardiac Dysfunction via the LKB1/AMPK/mTOR Axis in Mice

Yuan Wang, Shan Zhu, Hongtao Liu, Wen Wei, Yi Tu, Chuang Chen, Jun-Long Song, Juan-Juan Li, Shengrong Sun, Changhua Wang, Zhi-Liang Xu

Disease Markers

DOI

2019

Simple prosthesis versus prosthesis plus titanium-coated polypropylene mesh for implant-based immediate breast reconstruction after total mastectomy for breast cancer.

Xiao-Li Yao, Yue-Yue Guo, Yi Tu, Feng Yao, Chuang Chen, Shengrong Sun, Xing-Hua Zhang

Gland surgery

DOI

2019

Thyroxine Affects Lipopolysaccharide-Induced Macrophage Differentiation and Myocardial Cell Apoptosis via the NF-κB p65 Pathway Both In Vitro and In Vivo

Shan Zhu, Yuan Wang, Hongtao Liu, Wen Wei, Yi Tu, Chuang Chen, Jun-Long Song, Zhi-Liang Xu, Juan-Juan Li, Changhua Wang, Shengrong Sun

Mediators of Inflammation

DOI

2019

Minimally invasive comprehensive treatment for granulomatous lobular mastitis

Yaohuai Wang, Jun-Long Song, Yi Tu, Chuang Chen, Shengrong Sun

BMC Surgery

DOI

2018

Knockdown of B7H6 inhibits tumor progression in triple-negative breast cancer

Bing Zhang, Jin-Zhong Sun, Xiao-Li Yao, Juan-Juan Li, Yi Tu, Feng Yao, Shengrong Sun

Oncology Letters

DOI

2016

Characteristics of breast cancer in Central China, literature review and comparison with USA.

Chuang Chen, Si Sun, Jing-ping Yuan, Yaohuai Wang, Tian-Ze Cao, Hong-Mei Zheng, Xueping Jiang, Yiping Gong, Yi Tu, Feng Yao, Ming-Bai Hu, Juan-Juan Li, Shengrong Sun, Wen Wei

Breast

DOI

2015

Associations and indications of Ki67 expression with clinicopathological parameters and molecular subtypes in invasive breast cancer: A population-based study.

Jin-Zhong Sun, Chuang Chen, Wen Wei, Hong-Mei Zheng, Jingping Yuan, Yi Tu, Feng Yao, Li-Jun Wang, Xiao-Li Yao, Juan-Juan Li, Yan Li, Shengrong Sun

Oncology Letters

DOI

2014

Subtype classification for prediction of prognosis of breast cancer from a biomarker panel: correlations and indications

Chuang Chen, Jing-ping Yuan, Wen Wei, Yi Tu, Feng Yao, Xue-Qin Yang, Jin-Zhong Sun, Shengrong Sun, Yan Li

International Journal of Nanomedicine

DOI

2014

The co-expression of human epidermal growth factor 2 and collagen IV in human breast cancer tissues detected by quantum dots-based immunofluorescence technique and its clinical significance

Jie Ma, Shengrong Sun, Chuang Chen, Jin-Zhong Sun, Yi Tu

DOI

2013

Carbon nanoparticles suspension used in the central group lymph node dissection of papillary thyroid carcinoma

Zhi-liang Xu, Guannan Wang, Feng Yao, Yi Tu, Shengrong Sun

DOI

2013

Lymph node ratio is more predictive than traditional lymph node stratification in lymph node positive invasive breast cancer.

Lian Bai, Chuang Chen, Yiping Gong, Wen Wei, Yi Tu, Feng Yao, Juan-Juan Li, Li-Jun Wang, Shengrong Sun

Asian Pacific Journal of Cancer Prevention

DOI

2012

Expression of Survivin mRNA and protein in hepatoblastoma tissue

Yi Tu, Juan-Juan Li, He-Xiang Tong, Shengrong Sun

DOI

2012

Sonographically Guided Vacuum‐Assisted Breast Biopsy for Complete Excision of Presumed Benign Breast Lesions

Feng Yao, Juan-Juan Li, Yi Wan, Yunping Zhong, Wen Wei, Yi Tu, He-Xiang Tong, Shengrong Sun

Journal of ultrasound in medicine

DOI

2012

Compare the postoperative complications incidence of benign multi-nodular goiter: A meta-analysis

Pi-Lei Si, Yulin Xu, Yi Tu, Yi Guo, Shengrong Sun

DOI

2011

An autophagy inhibitor enhances the inhibition of cell proliferation induced by a proteasome inhibitor in MCF-7 cells.

Feng Yao, Guannan Wang, Wen Wei, Yi Tu, He-Xiang Tong, Shengrong Sun

Molecular Medicine Reports

DOI

2011

Effect of CCL2 on the expression of CCL, mRNA and the chemotactic activity in MCF-7 cells

Zhi-liang Xu, Shan Zhu, Yanyan Meng, Yulin Xu, Yi Tu, Shengrong Sun

DOI

2011

硼替佐米和3-甲基腺嘌呤对人乳腺癌细胞株MCF-7的抑瘤效应

Feng Yao, Guannan Wang, Wen Wei, Yi Tu, He-Xiang Tong, Shengrong Sun

2011

Combination of Fructose-1,6-Diphosphate and Proteasome Inhibitor Enhances Inhibition of Cell Proliferation in Human MCF-7 Breast Cancer Cells

Feng Yao, Guannan Wang, Juan-Juan Li, Yi Tu, Wen Wei, He-Xiang Tong, Shengrong Sun

DOI

2010

Role for ezrin in breast cancer cell chemotaxis to CCL5.

Juan-Juan Li, Yi Tu, Jing Wen, Feng Yao, Wen Wei, Shengrong Sun

Oncology Report

DOI

2009

The influence of silencing Ezrin expression by RNA interference on the biological behaviors of breast cancer cell line MCF-7

Juan-Juan Li, Yi Tu, Shengrong Sun

DOI

2007

DP-015-4 Role of JA in ablation therapy for experimental rat breast cancer

Feng Yao, Shengrong Sun, Jin-Zhong Sun, Hua-min Jin, Xiao-Li Yao, Bin Zhang, Yi Tu, Wen Wei

2007

肉芽肿性乳腺炎18例临床分析

Wen Wei, Yi Tu, Feng Yao, He-Xiang Tong, Shengrong Sun

DOI

2006

胃癌中微血管密度及VEGF、NOS表达与肿瘤浸润、转移的相关性

Yi Tu, Feng Yao, Wen Wei, Shengrong Sun

精选作品

期刊论文

癌症免疫反应中的代谢调节

Macrolide antibiotics activate the integrated stress response and promote tumor proliferation

In situ Injection of pH- and Temperature-Sensitive Nanomaterials Increases Chemo-Photothermal Efficacy by Alleviating the Tumor Immunosuppressive Microenvironment [Retraction]

DDOST调控抗病毒cGAS-MITA信号通路的分子机制

TLR与PI3K-Akt通路交互调控的研究进展

High Glucose Accelerates Tumor Progression by Regulating MEDAG-Mediated Autophagy Levels in Breast Cancer

PSMD12 promotes the activation of the MEK-ERK pathway by upregulating KIF15 to promote the malignant progression of liver cancer

In situ Injection of pH- and Temperature-Sensitive Nanomaterials Increases Chemo-Photothermal Efficacy by Alleviating the Tumor Immunosuppressive Microenvironment

Clinical and prognosis value of the number of metastatic lymph nodes in patients with papillary thyroid carcinoma

Differentiate Thermal Property of Mammary Glands for Precise Photothermal Therapy

MEDAG enhances breast cancer progression and reduces epirubicin sensitivity through the AKT/AMPK/mTOR pathway

Exosomal microRNAs in cancer-related sarcopenia: Tumor-derived exosomal microRNAs in muscle atrophy

Metabolic regulation in the immune response to cancer

IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms

An Albumin-Based Therapeutic Nanosystem for Photosensitizer/Protein Co-Delivery to Realize Synergistic Cancer Therapy.

AKT as a therapeutic target for autophagy induction and cancer therapy

Ceramide kinase mediates intrinsic resistance and inferior response to chemotherapy in triple‐negative breast cancer by upregulating Ras/ERK and PI3K/Akt pathways

PSMD8 Promotes Breast Cancer Progression and Attenuates Paclitaxel Sensitivity by Regulating the Expression of KIF10

Intraductal administration of N-methyl-N-nitrosourea as a novel rodent mammary tumor model

More Aggressive Cancer Behaviour in Thyroid Cancer Patients in the Post-COVID-19 Pandemic Era: A Retrospective Study

Patient-reported Outcomes of Patients With Breast Cancer During the COVID-19 Outbreak in the Epicenter of China: A Cross-sectional Survey Study

Appraisal of radioiodine refractory thyroid cancer: advances and challenges.

Quality Analysis of Chinese Popular Scientific Articles Pertaining to Novel Coronavirus Pneumonia

Galeterone sensitizes breast cancer to chemotherapy via targeting MNK/eIF4E and β-catenin

Isobacachalcone induces autophagy and improves the outcome of immunogenic chemotherapy

Clinical Characteristics and Outcomes of Single Versus Double Hormone Receptor-Positive Breast Cancer in 2 Large Databases.

Endoplasmic reticulum stress‐induced exosomal miR‐27a‐3p promotes immune escape in breast cancer via regulating PD‐L1 expression in macrophages

Abstract S07-02: Patient-reported outcomes of breast cancer patients during the COVID-19 outbreak in the epicenter of China: A cross-sectional survey study

Endoplasmic reticulum stress confers 5-fluorouracil resistance in breast cancer cell via the GRP78/OCT4/lncRNA MIAT/AKT pathway.

Interleukin-6 knockout reverses macrophage differentiation imbalance and alleviates cardiac dysfunction in aging mice

Thyroxine Alleviates Energy Failure, Prevents Myocardial Cell Apoptosis, and Protects against Doxorubicin-Induced Cardiac Injury and Cardiac Dysfunction via the LKB1/AMPK/mTOR Axis in Mice

Simple prosthesis versus prosthesis plus titanium-coated polypropylene mesh for implant-based immediate breast reconstruction after total mastectomy for breast cancer.

Thyroxine Affects Lipopolysaccharide-Induced Macrophage Differentiation and Myocardial Cell Apoptosis via the NF-κB p65 Pathway Both In Vitro and In Vivo

Minimally invasive comprehensive treatment for granulomatous lobular mastitis

Knockdown of B7H6 inhibits tumor progression in triple-negative breast cancer

Characteristics of breast cancer in Central China, literature review and comparison with USA.

Associations and indications of Ki67 expression with clinicopathological parameters and molecular subtypes in invasive breast cancer: A population-based study.

Subtype classification for prediction of prognosis of breast cancer from a biomarker panel: correlations and indications

The co-expression of human epidermal growth factor 2 and collagen IV in human breast cancer tissues detected by quantum dots-based immunofluorescence technique and its clinical significance

Carbon nanoparticles suspension used in the central group lymph node dissection of papillary thyroid carcinoma

Lymph node ratio is more predictive than traditional lymph node stratification in lymph node positive invasive breast cancer.

Expression of Survivin mRNA and protein in hepatoblastoma tissue

Sonographically Guided Vacuum‐Assisted Breast Biopsy for Complete Excision of Presumed Benign Breast Lesions

Compare the postoperative complications incidence of benign multi-nodular goiter: A meta-analysis

An autophagy inhibitor enhances the inhibition of cell proliferation induced by a proteasome inhibitor in MCF-7 cells.

Effect of CCL2 on the expression of CCL, mRNA and the chemotactic activity in MCF-7 cells

硼替佐米和3-甲基腺嘌呤对人乳腺癌细胞株MCF-7的抑瘤效应

Combination of Fructose-1,6-Diphosphate and Proteasome Inhibitor Enhances Inhibition of Cell Proliferation in Human MCF-7 Breast Cancer Cells

Role for ezrin in breast cancer cell chemotaxis to CCL5.

The influence of silencing Ezrin expression by RNA interference on the biological behaviors of breast cancer cell line MCF-7

DP-015-4 Role of JA in ablation therapy for experimental rat breast cancer

肉芽肿性乳腺炎18例临床分析

胃癌中微血管密度及VEGF、NOS表达与肿瘤浸润、转移的相关性

研究方向