百晓学者学者目录

丁立建

副教授、教授、研究员、硕士生导师,宁波大学

精选作品

期刊论文

2026

Unraveling Effects and Pharmacological Mechanisms of Phellodendrine on Inflammatory Bowel Disease

Yufeng Xie, Ziyi Zhou, Xuqianzi Wu, Jiayin Teng, Xiaorun Zhang, Yue Sun, Lixin Chen, Lijian Ding, Wei Yuan

Biomolecules

2026

Marine fungal-derived butyrolactone attenuates intestinal inflammation through MAPK/NF-κB and NLRP3 signaling pathway

Kuntian Tang, Jing-fei Lin, Lijian Ding, Chen Fen-Er

Bioorganic Chemistry

2026

A Comprehensive Insight of Mechanisms of Drugs Targeting Ion Channels: Exemplified by Marine Natural Products and Their Analogues

Dashuai Zhang, Shugeng Cao, Shan He, Shengjun Mao, Sulan Luo, Lijian Ding

Medicinal Research Reviews

2026

Design and synthesis of novel 1,2,4-triazolobenzene sulfonamide derivatives as selective CDK1 inhibitors with potent in vivo anticancer efficacy

Lingjie Wu, Ning Wang, Ning Wang, Yi Lu, Yang Wang, Lieen Ma, Gaojie Lou, Nan Wang, Nan Wang, Aili Jiang, Lijian Ding, Shan He, Bin Zhang

European Journal of Medicinal Chemistry

2025

Uncovering the therapeutic potentials of marine-derived natural compounds with small amounts for neurological disorders

Yirui Hong, Xinyu Zhang, Wenni Rong, Chenwei Hu, Yujie Jiang, Jiayi Xu, Huimin Wen, Fangjian Feng, C. Benjamin Naman, Haowei Shen, Shan He, Lijian Ding, Wei Cui

Gene

2025

SMART-assisted discovery of butenolides from the marine-derived Aspergillus sp. NBU4698 with multidrug resistance reversing and anti-inflammatory activity

Hang Zhao, Zhiyan Zhou, Fangjian Feng, Wei Yuan, Lixin Chen, C. Benjamin Naman, Zhiran Ju, Ziyi Zhou, Wenhan Lin, Shan He, Lijian Ding

Phytochemistry

2025

Discovery of Sesterdiaporate, an Antifungal Sesterterpene Lactone, against Penicillium italicum, Possibly via Inhibition of Glycosylphosphatidylinositol Biosynthesis from Diaporthe sp. HT-79

Liangliang Gao, Huiting Lin, Yan Liang, Mingnan You, Lijian Ding, Fangjian Feng, Qin Xiong, Yueming Jiang, Jun Zhang

Journal of Agricultural and Food Chemistry

2025

Chryxanthone A, an extracted substance from endophytic fungal Aspergillus versicolor, produces anti-oxidant neuroprotection possibly via the action on mTOR/CREB axis

Xinyu Zhang, Yirui Hong, Chenwei Hu, Yijie Zhai, N. Pan, Lijian Ding, Wenbo Han, Wei Cui

Gene

2025

Three New α-Pyrone Derivatives with Antiepileptic Activity from the Marine Actinomycete Nocardiopsis sp. NBUDK19

Jinling Li, Zhiyan Zhou, Fangjian Feng, Wei Yuan, Yawen Zhang, Jiaxing Wang, Bin Zhang, Haixiao Jin, Shan He, Lijian Ding

Marine Biotechnology

2024

Marine Staurosporine Analogues: Activity and Target Identification in Triple-Negative Breast Cancer

Ru-Yi Chen, Lijian Ding, Yan-Jun Liu, Jinjin Shi, Jing Xia Yu, Chang-Yun Li, Jianfei Lu, Guan‐Jun Yang, Jiong Chen

Marine Drugs

2024

Quinosumycin, a novel anti-MRSA thioether-linked quinolinone-quinazolinone heterodimer from a marine actinomycete Streptomyces diastaticus NBU2966

Shuangling Tan, Yang Liu, Haonan Fu, Yutong Xue, Fangjian Feng, Jinling Li, Xiaojun Yan, Sitong Wu, Shan He, Lijian Ding

Journal of Oceanology and Limnology

2024

The potential of marine natural products and their synthetic derivatives as drugs targeting ion channels

Da‐Shuai Zhang, Fangjian Feng, Yaoyao Chen, Jingyao Sui, Lijian Ding

European Journal of Medicinal Chemistry

2024

Antibiofilm Efficacy and Mechanism of the Marine Chlorinated Indole Sesquiterpene Against Methicillin-Resistant Staphylococcus aureus

Guobao Huang, Qiang Wang, Huimin Wen, Jinling Li, Shan He, Xiao Wang, Lijian Ding

Foodborne Pathogens and Disease

2024

Discovery of Antibacterial Compounds against Xanthomonas citri subsp. citri from a Marine Fungus Aspergillus terreus SCSIO 41202 and the Mode of Action

Jun Zhang, Liangliang Gao, Huiting Lin, Yan Liang, Mingnan You, Lijian Ding, Fangjian Feng, Bin Yang, Yonghong Liu

Journal of Agricultural and Food Chemistry

2024

Genomic Analysis of Kitasatospora setae to Explore Its Biosynthetic Potential Regarding Secondary Metabolites

Yutong Xue, Zhiyan Zhou, Fangjian Feng, Hang Zhao, Shuangling Tan, Jinling Li, Sitong Wu, Zhiran Ju, Shan He, Lijian Ding

Antibiotics

2024

Irpetones A and B, Anti-Osteoclastic Heptaketides from a Marine Mesophotic Zone Ircinia Sponge-Associated Fungus Irpex sp. NBUF088

Tingting Wang, Jiaxin Tian, Jian Huang, Ye Yuan, C. Benjamin Naman, Sitong Wu, Hong Wang, Wenhan Lin, Zhiwu Tong, Lijian Ding, Weiyi Wang, Shan He

Journal of Natural Products

2023

Asepterpenedol A, a novel indole sesquiterpene with a rare 7/6/5/5/6/6-hexacyclic scaffold from a marine-derived fungus Chloridium sp. NBU3282

Qiang Gao, Yutong Shi, Huimin Wen, Da‐Shuai Zhang, Xiaojun Yan, Shan He, Lijian Ding

Journal of Molecular Structure

2023

Antibacterial oxygenated ergostane-type steroids produced by the marine sponge-derived fungus Aspergillus sp.

Huimin Wen, Ya‐Wen Zhang, Fangjian Feng, Guobao Huang, Yu-Han Lv, Zou-Yan Zhang, Lijian Ding

Journal of Asian Natural Products Research

2023

Molecular networking-guided isolation of undescribed antifungal odoriferous sesquiterpenoids from a marine mesophotic zone sponge-associated Streptomyces sp. NBU3428

Huimin Wen, Da‐Shuai Zhang, Hang Zhao, Yawen Zhang, Xiaojun Yan, Wenhan Lin, Shan He, Lijian Ding

Phytochemistry

2023

Bresmycins A and B, potent anti-breast cancer indolocarbazole alkaloids from the sponge-associated Streptomyces sp. NBU3142

Lijian Ding, Wenhao Li, Xiao-Dan Zhong, Fangjian Feng, Xin Yi, Xiaojun Yan, J. Enrico H. Lazaro, Bin Zhang, Yutong Shi, Guan‐Jun Yang, Shan He

Journal of Molecular Structure

2023

A New Antibacterial Dihydroisocoumarin from the Marine Sponge-Associated Fungus Aspergillus sp.

Sixiao Lin, Juan Li, Weizhong Chen, Jiaxin He, Yutong Shi, Haixiao Jin, Lijian Ding

Chemistry of Natural Compounds

2023

Discovery of novel polysubstituted N -alkyl acridone analogues as histone deacetylase isoform-selective inhibitors for cancer therapy

Ze Wang, Zhao Li, Bo Zhang, Bo Zhang, Jiahe Feng, Yule Wang, Bin Zhang, Bin Zhang, Haixiao Jin, Lijian Ding, Ning Wang, Shan He

Journal of Enzyme Inhibition and Medicinal Chemistry

2022

Dibetanide, a new benzofuran derivative with the rare conjugated triene side chain from a sponge-associated fungus Aspergillus species

Wenhao Li, Qiang Gao, Yanjie Hu, Yutong Shi, Xiaojun Yan, Lijian Ding, Shan He

Journal of Molecular Structure

2022

Novel Antimycin Analogues with Agricultural Antifungal Activities from the Sponge-Associated Actinomycete Streptomyces sp. NBU3104

Wenhao Li, Lijian Ding, Juan Li, Huimin Wen, Yang Liu, Shuangling Tan, Xiaojun Yan, Yutong Shi, Wenhan Lin, Hou‐Wen Lin, Shan He

Journal of Agricultural and Food Chemistry

2022

Marine natural products and their synthetic analogs as promising antibiofilm agents for antibiotics discovery and development

Yueting Deng, Yang Liu, Juan Li, Xiao Rui Wang, Shan He, Xiaojun Yan, Yutong Shi, Weiyan Zhang, Lijian Ding

European Journal of Medicinal Chemistry

2022

Discovery of New Secondary Metabolites from Marine Bacteria Hahella Based on an Omics Strategy

Shufen He, Peishan Li, Jingxuan Wang, Yanzhu Zhang, Hongmei Lü, Liufei Shi, Tao Huang, Weiyan Zhang, Lijian Ding, Shan He, Liwei Liu

Marine Drugs

2022

Molecular Networking-Driven Discovery of Antibacterial Perinadines, New Tetracyclic Alkaloids from the Marine Sponge-Derived Fungus Aspergillus sp.

Yang Liu, Lijian Ding, Yutong Shi, Xiaojun Yan, Bin Wu, Shan He

ACS Omega

2022

Targeted Discovery of Amantamide B, an Ion Channel Modulating Nonapeptide from a South China Sea Oscillatoria Cyanobacterium

Te Li, Chuchu Xi, Yiyi Yu, Ning Wang, Xiao Wang, Arihiro Iwasaki, Fang Fang, Lijian Ding, Shuang Li, Weiyan Zhang, Ye Yuan, Tingting Wang, Xiaojun Yan, Shan He, Zhengyu Cao, C. Benjamin Naman

Journal of Natural Products

2022

Feature-based molecular networking-guided discovery of siderophores from a marine mesophotic zone Axinellida sponge-associated actinomycete Streptomyces diastaticus NBU2966

Yang Liu, Lijian Ding, Yueting Deng, Xiao Wang, Wei Cui, Shan He

Phytochemistry

2022

A state-of-the-art review on LSD1 and its inhibitors in breast cancer: Molecular mechanisms and therapeutic significance

Guan‐Jun Yang, Yanjun Liu, Lijian Ding, Fan Tao, Minghui Zhu, Zhen-Yuan Shi, Juan-Ming Wen, Meng-Yao Niu, Li Xiang, Zhan-Song Xu, Wan‐Jia Qin, Chen-Jie Fei, Jiong Chen

Frontiers in Pharmacology

2022

Front Cover: Guignardones Y–Z, Antiviral Meroterpenes from Penicillium sp. NBUF154 Associated with a Crella Sponge from the Marine Mesophotic Zone (Chem. Biodiversity 8/2022)

Jiabin Zou, Jialing Wu, Lijian Ding, Weiyi Wang, Yinghui Liu, Yunping Feng, Qiliang Lai, Wenhan Lin, Tingting Wang, Shan He

Chemistry & Biodiversity

2022

Guignardones Y–Z, Antiviral Meroterpenes from Penicillium sp. NBUF154 Associated with a Crella Sponge from the Marine Mesophotic Zone

Jiabin Zou, Jialing Wu, Lijian Ding, Weiyi Wang, Yinghui Liu, Yunping Feng, Qiliang Lai, Wenhan Lin, Tingting Wang, Shan He

Chemistry & Biodiversity

2021

A new antibacterial chromone from a marine sponge-associated fungus Aspergillus sp. LS57

Yang Liu, Lijian Ding, Jiaxin He, Ziming Zhang, Yueting Deng, Shan He, Xiaojun Yan

Fitoterapia

2021

Metabolomic Characterization of a cf. Neolyngbya Cyanobacterium from the South China Sea Reveals Wenchangamide A, a Lipopeptide with In Vitro Apoptotic Potential in Colon Cancer Cells

Lijian Ding, Rinat Bar‐Shalom, Dikla Aharonovich, Naoaki Kurisawa, Gaurav Patial, Shuang Li, Shan He, Xiaojun Yan, Arihiro Iwasaki, Kiyotake Suenaga, Cheng-Cong Zhu, Haixi Luo, Fuli Tian, Fuad Fares, C. Benjamin Naman, Tal Luzzatto‐Knaan

Marine Drugs

2021

Rapid separation and purification of two C25 steroids with bicyclic [4.4.1] A/B rings from the marine fungus Aspergillus sp. LS116 by high-speed counter-current chromatography in stepwise elution mode

Zhende Dou, Xiaoping He, Peng Xu, Bin Zhang, Lijian Ding

Natural Product Research

2020

Antiviral potential of natural products from marine microbes

Mengqi Yi, Sixiao Lin, Bin Zhang, Haixiao Jin, Lijian Ding

European Journal of Medicinal Chemistry

2020

Marine Sponge-Associated Fungi as Potential Novel Bioactive Natural Product Sources for Drug Discovery: A Review

Bin Zhang, Ting Zhang, Jianzhou Xu, Jian Qi Lu, Panpan Qiu, Tingting Wang, Lijian Ding

Mini-Reviews in Medicinal Chemistry

2020

New antifungal tetrahydrofuran derivatives from a marine sponge-associated fungus Aspergillus sp. LS78

Yang Liu, Lijian Ding, Ziming Zhang, Xiaojun Yan, Shan He

Fitoterapia

2020

Recent advances in chemistry and bioactivity of marine cyanobacteria Moorea species

Jianzhou Xu, Ting Zhang, Jiaxiao Yao, Jian Qi Lu, Zhiwen Liu, Lijian Ding

European Journal of Medicinal Chemistry

2020

Three New Diketopiperazines from the Previously Uncultivable Marine Bacterium Gallaecimonas mangrovi HK‐28 Cultivated by iChip

Lijian Ding, Peng Xu, Weiyan Zhang, Ye Yuan, Xiaoping He, Dengquan Su, Yutong Shi, C. Benjamin Naman, Xiaojun Yan, Bin Wu, J. Enrico H. Lazaro, Shengying Li, Shan He

Chemistry & Biodiversity

2020

A New Antibacterial Chlorinated Amino Acid Derivative from the Sponge-Derived Fungus Aspergillus sp. LS53

Lu Zhang, Panpan Qiu, Lijian Ding, Qiang Li, Jingjing Song, Zhiwen Han, Shan He

Chemistry of Natural Compounds

2019

海绵共附生真菌Aspergillus niger的分离鉴定及抗菌抗氧化活性物质研究

姚佳晓,张作艳,张云阳,符浩男,肖烨,丁立建,何山

《中药材》

2019

1株海南三亚红树林真菌Alternaria alternate次级代谢产物的研究

姚佳晓,贺小平,周培娟,张云阳,肖烨,伊梦麒,丁立建,何山

《中国海洋药物》

2019

Inhibition of acetylcholinesterase activity and β‑amyloid oligomer formation by 6‑bromotryptamine�A, a multi‑target anti‑Alzheimer's molecule

Xiaofeng Jin, Minjun Wang, Jieyi Shentu, Chunhui Huang, Yujing Bai, Hanbo Pan, Difan Zhang, Zhijun Yuan, Hui Zhang, Xiao Xiao, Xiang Wu, Lijian Ding, Qinwen Wang, Shan He, Wei Cui

Oncology Letters

2019

New Dihydroisocoumarin Root Growth Inhibitors From the Sponge-Derived Fungus Aspergillus sp. NBUF87

Liming Huang, Lijian Ding, Xiaohui Li, Ning Wang, Wei Cui, Xiao Dan Wang, C. Benjamin Naman, J. Enrico H. Lazaro, Xiaojun Yan, Shan He

Frontiers in Microbiology

2019

A Review of Anti-Inflammatory Compounds from Marine Fungi, 2000–2018

Jianzhou Xu, Mengqi Yi, Lijian Ding, Shan He

Marine Drugs

2019

A new aquatic pathogen inhibitor produced by the marine fungus Aspergillus sp. LS116

Peng Xu, Lijian Ding, Jiaxin Wei, Qiang� Li, Minjie Gui, Xiaoping He, Dengquan Su, Shan He, Haixiao Jin

Aquaculture

2019

Production of New Antibacterial 4-Hydroxy-α-Pyrones by a Marine Fungus Aspergillus niger Cultivated in Solid Medium

Lijian Ding, Lu Ren, Shuang Li, Jingjing Song, Zhiwen Han, Shan He, Shi‐Hai Xu

Marine Drugs

2019

Penichrypyrone A: A New γ-Pyrone Derivative from the Sponge-Derived Fungus Penicillium chrysogenum LS18

Xiaoping He, Lu Ren, Lijian Ding, Jianzhou Xu, Bin Zhang, Weiyan Zhang, Shan He

Natural Product Communications

2019

Separation of five diketopiperazines from the marine fungus Alternaria alternate HK‐25 by high‐speed counter‐current chromatography

Xiaoping He, Lijian Ding, Mengqi Yi, Jianzhou Xu, Xuezhen Zhou, Weiyan Zhang, Shan He

Journal of Separation Science

2019

Isolation and Characterization of Two New Metabolites from the Sponge-Derived Fungus Aspergillus sp. LS34 by OSMAC Approach

Wei Li, Lijian Ding, Ning Wang, Jianzhou Xu, Weiyan Zhang, Bin Zhang, Shan He, Bin Wu, Haixiao Jin

Marine Drugs

2019

A new lateral root growth inhibitor from the sponge-derived fungus Aspergillus sp. LS45

Liming Huang, Lijian Ding, Xiaohui Li, Ning Wang, Yushan Yan, Mengxiang Yang, Wei Cui, C. Benjamin Naman, Kejun Cheng, Weiyan Zhang, Bin Zhang, Haixiao Jin, Shan He

Bioorganic & Medicinal Chemistry Letters

2019

Isolation and Purification of a Neuroprotective Phlorotannin from the Marine Algae Ecklonia maxima by Size Exclusion and High-Speed Counter-Current Chromatography

Xuezhen Zhou, Mengqi Yi, Lijian Ding, Shan He, Xiaojun Yan

Marine Drugs

2019

Highly Oxidized Ergosterol Derivatives from the Fungus Nigrospora oryzae

Jiaxiao Yao, Yuanmei Shi, Yong Liu, Shan He, Lijian Ding, Fan Yang

Chemistry of Natural Compounds

2018

海洋真菌Alternaria alternate YX-25和放线菌Streptomyces exfoliates YX-32共培养的次级代谢产物研究

贺小平,粟登权,丁立建,何山

《中草药》

2018

Haliclona属海绵化学成分及生物活性研究新进展

田祥云,何山,丁立建

《天然产物研究与开发》

2018

未培养微生物原位培养技术研究进展

张作艳,丁立建,何山

《天然产物研究与开发》

2018

高速逆流色谱分离真菌Aspergullus versicolor中二苯醚类化合物

周珂昕,朱静轩,丁立建,何山

《天然产物研究与开发》

2018

Marine-derived Trichoderma Species as a Promising Source of Bioactive Secondary Metabolites

Dengquan Su, Lijian Ding, Shan He

Mini-Reviews in Medicinal Chemistry

2018

Asperitaconic acids A–C, antibacterial itaconic acid derivatives produced by a marine-derived fungus of the genus Aspergillus

Lijian Ding, Te Li, Xiao-Jian Liao, Shan He, Shi‐Hai Xu

The Journal of Antibiotics

2018

A New Cyclopentenone Derivative from the Sponge-Associated Fungus Hypocrea koningii

Panpan Qiu, Lijian Ding, Dengquan Su, Shan He

Chemistry of Natural Compounds

2018

Asperfurandiones A and B, two antifungal furandione analogs from a marine-derived fungus Aspergillus versicolor

Lijian Ding, Peng Xu, Te Li, Xiaojian Liao, Shan He, Shi‐Hai Xu

Natural Product Research

2018

Discovery of a new biphenyl derivative by epigenetic manipulation of marine-derived fungus Aspergillus versicolor

Jing Zhu, Lijian Ding, Shan He

Natural Product Research

2018

Penicillilactone A, a novel antibacterial 7-membered lactone derivative from the sponge-associated fungus Penicillium sp. LS54

Yong Liu, Lijian Ding, Fang Fang, Shan He

Natural Product Research

2018

Preparative Separation and Purification of Trichothecene Mycotoxins from the Marine Fungus Fusarium sp. LS68 by High-Speed Countercurrent Chromatography in Stepwise Elution Mode

Yong Liu, Xuezhen Zhou, C. Benjamin Naman, Yanbin Lu, Lijian Ding, Shan He

Marine Drugs

2017

蜂海绵共附生真菌Aspergillus sp. LS06次级代谢产物研究

斯远梅,张诗敏,姚佳晓,朱静轩,何山,丁立建

《中药材》

2017

表观遗传试剂诱导海洋真菌Aspergillus versicolor DJ013产生次级代谢产物的研究

朱静轩,王婷婷,周珂欣,丁立建,吴小凯,何山

《中国海洋药物》

2017

5-Hydroxycyclopenicillone, a New β-Amyloid Fibrillization Inhibitor from a Sponge-Derived Fungus Trichoderma sp. HPQJ-34

Fang Fang, Jiaying Zhao, Lijian Ding, Chunhui Huang, C. Benjamin Naman, Shan He, Bin Wu, Peng Zhu, Qijun Luo, William H. Gerwick, Xiaojun Yan, Qinwen Wang, Yifan Han, Wei Cui

Marine Drugs

2016

Efficient Preparation of Streptochlorin from Marine Streptomyces sp. SYYLWHS-1-4 by Combination of Response Surface Methodology and High-Speed Counter-Current Chromatography

Lin Li, Shan He, Lijian Ding, Ye Yuan, Peng Zhu, Slava S. Epstein, Jianzhong Fan, Xiaokai Wu, Xiaojun Yan

Molecules

2015

Discovery and Structure-Based Optimization of 6-Bromotryptamine Derivatives as Potential 5-HT2A Receptor Antagonists

Lijian Ding, Shan He, Wei Wu, Haixiao Jin, Peng Zhu, Jinrong Zhang, Tingting Wang, Ye Yuan, Xiaojun Yan

Molecules

2014

海洋交替假单胞菌QD1-2抗肿瘤活性辅酶Q衍生物的分离与结构鉴定

陈晓兰,丁立建,何山

《天然产物研究与开发》

2014

Efficient preparation of pseudoalteromone A from marine Pseudoalteromonas rubra QD1-2 by combination of response surface methodology and high-speed counter-current chromatography: a comparison with high-performance liquid chromatography

Lijian Ding, Shan He, Xiaojun Yan

Applied Microbiology and Biotechnology

2013

海洋交替假单胞菌活性物质的研究

丁立建,何山,严小军

《天然产物研究与开发》

会议论文

2018

海洋生物来源的活性小分子化合物

徐石海,赵冰心,廖小健,张军,丁立建,陈胜添

《中国化学会第十二届全国天然有机化学学术会议论文摘要集》

2017

南海海洋生物代谢产物及其活性

廖小建,赵冰心,张军,丁立建,徐石海

《中国化学会第十九届全国有机分析及生物分析学术研讨会》

2016

来源于海洋微生物的代谢产物及生物活性

廖小建,赵冰心,陈胜添,丁立建,鞠志冉,徐石海

《中国化学会第十一届全国天然有机化学学术会议论文集(第三册)》

2015

海洋生物活性成分多样性及构效关系

廖小健,白德发,张军,丁立建,鞠志冉,肖茜,徐石海

《第十二届海洋药物学术年会》

2015

南海海绵及相关微生物的环肽化学及活性研究

韩兵男,战凯璇,袁薇,丁立建,李玉山,林厚文

《全国第二届海洋与陆地多糖多肽及天然创新药物研发学术会议论文集》

2014

海绵共附生真菌Nigrospora oryzae次生代谢产物研究

丁立建,焦伟华,杨帆,徐石海,林厚文

《2014年中国药学大会暨第十四届中国药师周论文集》

预印本

2025

Chejuenolide D, an Anti-inflammatory 17-Membered Macrocyclic Polyketide from an iChip-Domesticated Marine Bacterium Hahella sp. NBU794

Fangjian Feng, Zhiran Ju, Guobao Huang, Dengquan Su, Bin Wu, Weiyan Zhang, Shan He, Lijian Ding

Research Square

研究方向

此主页由公开资料整理,尚未经学者本人认领。